Matches 1 - 50 out of 149 1 2 3 >


Match Document Document Title
US20110293723 SYNTHETIC NANOCARRIER COMBINATION VACCINES  
Disclosed are dosage forms and related methods, that include a first population of synthetic nanocarriers that have one or more first antigens coupled to them, one or more second antigens that are...
US20150071879 Stabilization of Aqueous Compositions of Proteins with Displacement Buffers  
An aqueous composition having increased protein stability is obtained by: a. determining a pH at which the protein has stability at the desired temperature; b. adding to the composition at least...
US20140350483 Injections  
A syringe containing a compressible porous matrix, which compressible porous matrix has in it a pharmaceutical in a soluble glass, Methods of producing and using the syringe, and compressible...
US20110110979 METHOD AND VACCINE FOR OPTIMIZING THE SPECIFIC IMMUNE RESPONSES  
The present invention relates to a method for treating an infection or disease or lesion, in particular an HPV infection. Furthermore, it relates to a vaccine for treating a Human Papillomavirus...
US20140050763 MODIFIED VIRAL PARTICLES WITH IMMUNOGENIC PROPERTIES AND REDUCED LIPID CONTENT USEFUL FOR TREATING AND PREVENTING INFECTIOUS DISEASES  
The present invention relates to a method for reducing the occurrence and severity of infectious diseases, especially infectious diseases in which lipid-containing infectious viral organisms are...
US20140099339 VACCINE AGAINST STREPTOCOCCUS PNEUMONIAE  
The present invention relates to a combination of 2 or more S pneumoniae proteins, their manufacture and use in medicine as a vaccine. Such combinations are particularly useful for the protection...
US20140341974 Liposomal Vaccine Adjuvants and Methods of Making and Using Same  
A vaccine adjuvant composition comprising: a lipid selected from the group consisting of: dipalmitoyl phosphatidicholine (DPPC), dipalmitoyl phosphatidylglycerol (DPPG), dioleoyl...
US20140065100 Compositions and Methods for Cancer Immunotherapy  
The invention relates to immunotherapeutic compounds and to methods for stimulating an immune response in a subject individual at risk for developing cancer, diagnosed with a cancer, in treatment...
US20120003277 NANOEMULSION VACCINES  
The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides nanoemulsion compositions harboring one or more...
US20120045511 THERMOSENSITIVE HEPATITIS B VACCINE  
A thermosensitive hepatitis B vaccine is provided. The thermosensitive hepatitis B vaccine includes an aqueous phase solution comprising a biodegradable thermosensitive hydrogel copolymer; a...
US20110097362 Transmucosal Administration of Aggregated Antigens  
The present invention relates to modulation of the immune response in a mammal. In particular, the invention relates to methods of inducing oral tolerance and systemic immunity in a mammal. The...
US20140219954 DRY POWDER FORMULATIONS OF ORGANIC MACROMOLECULES  
The present invention relates to methods for making a stabilized powder formulation for inhalation comprising a macromolecule in lyophilized form, a crystalline carrier material, and magnesium...
US20140220076 Recombinant Mistletoe Lectin and use Thereof as an Adjuvant  
The invention relates to vaccines that comprise antigens and an adjuvant, and to the use of the adjuvant, wherein the adjuvant is selected from a recombinant mistletoe lectin.
US20120219589 FORMULATION OF DRUGS AND VACCINES IN THE FORM OF PERCUTANEOUS INJECTABLE NEEDLES  
The invention relates to percutaneous administration of drugs and vaccines in form of solid penetrating needles, “injectable needles”, comprising a polymeric matrix resulting from the...
US20140255446 ACELLULAR PERTUSSIS VACCINE  
Described are acellular pertussis (aP) vaccine compositions comprising Bordetella pertussis antigens pertussis toxoid (PT), filamentous hemagglutinin (FHA), and fimbriae types 2 and 3 (FIM), and...
US20120263755 METHODS AND COMPOSITIONS FOR ELICITING AN IMMUNE RESPONSE AGAINST HEPATITIS B VIRUS  
The present invention relates to immunization of hypo-responsive groups of individuals. In particular, the present invention provides methods and compositions for eliciting a potent immune...
US20130344106 Methods and Compositions for Improving Immune Response by a Nutraceutical Antioxidant  
The present invention provides a new means of restoring the immune system in aging and immunocompromised individuals using an antioxidant nutraceutical. The nutraceutical stimulates the aging...
US20120039842 COMPOSITIONS AND METHODS THAT ENHANCE AN IMMUNE RESPONSE  
Disclosed herein are isolated nucleic acids, compositions of isolated nucleic acids, and compositions of polypeptides that are useful for the generation, enhancement, or improvement of an immune...
US20120258137 IMMUNOGENIC COMPOSITIONS COMPRISING NANOEMULSION AND HEPATITIS B VIRUS IMMUNOGEN AND METHODS OF USING THE SAME  
The invention provides immunogenic compositions and methods of using the same to induce immune responses (e.g., humoral, mucosal, and/or cell-mediated immune responses) against Hepatitis B virus...
US20120308615 FORMULATION OF HEPATITIS B VIRUS ANTIGENS FOR CELLULAR STIMULATION FOLLOWED BY THERAPEUTIC IMMUNIZATION  
The present invention is related with the field of the therapeutic immunization, specifically with the employment of a new formulation of antigens of the Hepatitis B Virus (HBV) for the cellular...
US20110165194 HBV Vaccine and a Process of Preparing the Same  
The present invention relates to an HBV vaccine comprising an entire hepatitis B surface antigen of L protein, M protein and S protein, in which the produced antigens form virus-like particles,...
US20140112954 METHOD FOR PREPARING HBV VACCINE COMPRISING ALUMINUM ADJUVANT  
The present invention discloses a method for preparing HBV Vaccine comprising aluminum adjuvant, which belongs to biological technology field. The method, which is characterized in that aluminum...
US20140314739 Vaccine adjuvant composition comprising inulin particles  
The present invention provides a composition comprising or consisting of inulin particles for use in the reduction or inhibition of inflammation, and/or for treating or preventing inflammatory...
US20130095134 STABILIZED VIRUS LIKE PARTICLES HAVING ENHANCED MUCOSAL IMMUNOGENICITY  
This disclosure relates to compositions and methods for inducing immune response. Specifically, the disclosure relates to a composition comprising a subunit antigen stabilized by a...
US20150004194 FACILITATOR-DNA COMBINATION VACCINE  
Provided herein is a vaccine that combines a vaccine facilitator and a DNA construct encoding an antigen to elicit antigen-specific antibody responses, wherein the vaccine facilitator is a Na/K...
US20120258135 IMMUNOGENIC ANTI-INFLAMMATORY COMPOSITIONS  
The invention provides methods of formulating an anti-inflammatory composition for treating inflammatory conditions in a specific organ or tissue. The method involves selecting at least one...
US20150132258 AZEPANE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS  
Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV...
US20140322272 VACCINE  
The present invention provides immunogenic compositions comprising one or more antigens and an adjuvant for use in cutaneous immunisation wherein said adjuvant is an immunologically active saponin.
US20120045430 DENDRIMER-LIKE MODULAR DELIVERY VECTOR  
Various nucleic acid-based matrixes are provided, comprising nucleic acid monomers as building blocks, as well as nucleic acids encoding proteins, so as to produce novel biomaterials. The nucleic...
US20100266534 Human Lymphocyte Vaccine Adjuvant  
The present invention relates to an adjuvant derived from human lymphocytes. The adjuvant can be used in combination with traditional vaccines or cancer immunotherapy, to enhance the response of...
US20140178431 LIPID AND NITROUS OXIDE COMBINATION AS ADJUVANT FOR THE ENHANCEMENT OF THE EFFICACY OF VACCINES  
The invention provides for a method of enhancing immunological responses to an antigen in a vaccine formulation, and for a vaccine formulation that provides for an enhanced immunological response...
US20140112951 Vaccine and drug delivery by topical application of vectors and vector extracts  
Disclosed and claimed is a method of non-invasive immunization in an animal and/or a method of inducing a systemic immune response or systemic therapeutic response to a gene product. The skin of...
US20140322271 VACCINE COMPRISING A TLR-5 AGONIST AS ADJUVANT FOR USE IN CUTANEOUS IMMUNISATION  
The present invention provides immunogenic compositions comprising one or more antigens and an adjuvant for use in cutaneous immunisation wherein said adjuvant is a TLR-5 agonist.
US20110002961 Interleukin 12 paracrine gene delivery enhanced CTL immunotherapy  
A method of treating a patient with a disease wherein the patient contains diseased cells which cells contain antigens for identification and which cells are capable of presenting at least part of...
US20110293658 USE OF INKT OR TLR AGONISTS FOR PROTECTING AGAINST OR TREATING A DISEASE SUCH AS ACUTE INFECTION OR CANCER  
A method of protecting a mammalian subject against, or treating, a disease, wherein the mammalian subject has elevated numbers and/or activities of MDSC comprising administering to the subject a...
US20130115244 Immunogenic Substances Comprising a Polyinosinic Acid - Polycytidilic Acid Based Adjuvant  
The present invention provides a polynucleotide adjuvant (PICKCa) composition and methods of use in eliciting an immune response, in particular a mucosal immune response. The polynucleotide...
US20100040576 Modified Oligonucleotides For The Treatment Of Hepatitis C Infection  
The invention relates to compositions and methods related to the treatment of viral infection. In some embodiments, the invention relates to the treatment of hepatitis C viral infection. In...
US20120171244 MUCOSAL BOOSTING FOLLOWING PARENTERAL PRIMING  
Mucosal immunization using one or more antigens following parenteral administration of the same or different antigens is described.
US20140023613 Nucleic Acid Molecule Encoding Hepatitis B Virus Core Protein And Vaccine Comprising The Same  
Provided herein are nucleic acid sequences that encode novel consensus amino acid sequence of HBV core protein, as well as genetic constructs/vectors and vaccines that express said protein...
US20140186292 DEFECTIVE RIBOSOMAL PRODUCTS IN BLEBS (DRIBBLES) AND METHODS OF USE TO STIMULATE AN IMMUNE RESPONSE  
Methods are disclosed for producing defective ribosomal products (DRiPs) in blebs (DRibbles) by contacting cells with a proteasome inhibitor, and in some examples also an autophagy inducer,...
US20110091501 Recombinant Rhinovirus Vectors  
The invention provides rhinovirus vectors, which can be used in the delivery of immunogens, such as influenza virus immunogens, and corresponding compositions and methods.
US20140161826 NON-SELF T-CELL EPITOPE FUSED TO AN ANTIBODY THAT RECOGNISES A TUMOUR-SPECIFIC CELL-SURFACE RECEPTOR AND USES THEREOF  
A first composition comprising a ligand part being able to specifically bind to a target, the target being on a diseased cell of an organism, and an epitope part having a non-self epitope, or...
US20090214592 Adjuvant composition comprising aluminium phosphate and 3D-MPL  
An immunogenic composition comprising: (i) an antigen; (ii) an aluminum phosphate adjuvant; and (iii) a 3-O-deacylated monophosphoryl lipid A adjuvant. Components (ii) and (iii) can also be used...
US20150152154 TUMOR VACCINATION INVOLVING A HUMORAL IMMUNE RESPONSE AGAINST SELF-PROTEINS  
The present invention relates to tumor immunotherapy, in particular to tumor vaccination, using chimeric proteins comprising all or a portion of a hepatitis B virus core antigen protein and an...
US20130052217 TUMOR VACCINATION INVOLVING A HUMORAL IMMUNE RESPONSE AGAINST SELF-PROTEINS  
The present invention relates to tumor immunotherapy, in particular to tumor vaccination, using chimeric proteins comprising all or a portion of a hepatitis B virus core antigen protein and an...
US20130309268 COMPOSITIONS INCLUDING TRANSFER FACTOR DERIVED FROM EGGS  
A non-mammalian transfer factor, compositions including the non-mammalian transfer factor, and methods for generating and preparing the non-mammalian transfer factor. The non-mammalian transfer...
US20110059132 COMPOSITION FOR THERAPY AND/OR FOR PROPHYLAXIS OF HBV-INFECTIONS AND HBV-MEDIATED DISEASES  
The present invention relates to a composition, comprising: i) an HBcAg1-x, wherein x is a whole number from the range from 100 to 160, a fragment of this antigen, a variant of this antigen or of...
US20100247573 Stabilization of Vaccines by Lyophilization  
This invention provides pharmaceutical compositions, such as vaccines, and methods of making and using such compositions.
US20100316669 VACCINE FORMULATION POTENTIATED BY THE COMBINATION OF DNA AND AN ANTIGEN  
Formulation of vaccine antigens, containing as main components: a-) one or several DNA expressing one or several proteins in the immunized individuals and b-) a viral antigen, in appropriate...
US20090311288 IMIDAZOQUINOXALINE COMPOUNDS AS IMMUNOMODULATORS  
The invention proyides novel compositions comprising imidazoquinoxaline compounds of formula (I) and analogs thereof. Also provided are methods of administering the compositions in an effective...

Matches 1 - 50 out of 149 1 2 3 >