Matches 1 - 50 out of 79 1 2 >


Match Document Document Title
US20150132340 CATIONIC LIPID VACCINE COMPOSITIONS AND METHODS OF USE  
The present disclosure provides vaccine compositions comprising at least one adjuvant and at least one therapeutic factor. The disclosure also provides methods of reducing an immune suppressor...
US20120014987 DNA VACCINE FOR ALZHEIMER'S DISEASE  
The present invention aims to provide a DNA vaccine for Alzheimer's disease. The present invention provides a recombinant vector which comprises DNA encoding amyloid β and DNA encoding a Th2...
US20110064762 PROTEIN A COMPOSITIONS AND METHODS OF USE  
Methods and compositions for modulating an immune response in a subject are provided. Methods include administering to the subject a composition comprising an effective amount of a lymphocyte...
US20110274718 System for Modulating Expression of Hypothalmic Brain-Derived Neurotrophic Factor (BDNF)  
Methods for treating tumor associated diseases by administering a nucleic acid sequence encoding brain derived neurotrophic factor (BDNF) where the expression reduces the symptoms of the disease...
US20110274649 T-CELL VACCINATION WITH VIRAL VECTORS VIA MECHANICAL EPIDERMAL DISRUPTION  
Attenuated, replication-deficient viruses such as vaccinia viruses are used to deliver an exogenous viral, bacterial, parasitic or tumor antigen to an epidermal tissue such as the skin, lungs or...
US20140050741 SYNTHETIC LTA MIMETICS AND USE THEREOF AS VACCINE COMPONENT FOR THERAPY AND/OR PROPHYLAXIS AGAINST GRAM-POSITIVE INFECTIONS  
The present invention relates to synthetic lipoteicoic acid (LTA) mimetics which are useful as vaccine components for therapy and/or prophylaxis of bacterial infection.
US20150147388 Materials and Methods for Modulating immune Responses  
The present invention provides materials and methods for modulating an immune response. In one embodiment, the present invention provides an initial artificial lymph-node homing environment, and a...
US20140248211 METHOD OF TREATING CANCER  
The invention provides a method for treating cancer using a coadministration strategy that combines local codelivery of a therapeutic agent and an intracellular penetration enhancing agent, and...
US20110206680 METHODS FOR TREATING PSORIASIS  
The invention provides methods of treating psoriasis in a subject by administering to a subject an antibody capable of binding to the p40 subunit of IL-12 and/or IL-23.
US20150079026 Controlled Release Formulations for the Induction and Proliferation of Blood Cells  
The absence of regulatory T cells (Treg) may underlie disorders including but not limited to autoimmunity, dermatitis, periodontitis and even transplant rejection. Enhancing local numbers of Treg...
US20110195080 Compositions and Methods for Enhanced Somatostatin Immunogenicity in the Treatment of Growth Hormone and Insulin-Like Growth Factor One Deficiency  
Compositions and methods are provided for treatment growth hormone and/or insulin-like growth factor 1 deficiency in a patient in need of such treatment. Compositions and methods include novel...
US20110086061 Cancer Detection Methods and Reagents  
The present invention comprises methods and compositions for detecting cancer in an individual comprising autoantibodies to cancer-associated antigens. Specifically, the present invention...
US20110052576 VEGF-SPECIFIC ANTAGONISTS FOR ADJUVANT AND NEOADJUVANT THERAPY AND THE TREATMENT OF EARLY STAGE TUMORS  
Disclosed herein are methods of treating benign, pre-cancerous, or non-metastatic tumors using an anti-VEGF-specific antagonist. Also disclosed are methods of treating a subject at risk of...
US20100316603 Combination Immunogene Therapy  
The present invention provides to immunogene therapy protocols for the treatment of tumors. In particular, the present invention provides combinations of immune-modulating proteins that induce...
US20110236406 IMMUNOGENIC COMPOSITIONS COMPRISING HMGB1 POLYPEPTIDES  
The present invention relates to novel immunogenic compositions (e.g., vaccines), the production of such immunogenic compositions and methods of using such compositions. More specifically, this...
US20110044945 AGENTS FOR THE TREATMENT OF MULTIPLE SCLEROSIS AND METHODS OF USING SAME  
A method of treating Multiple Sclerosis is disclosed. The method comprises administering to the subject a therapeutically effective amount of SDF-1 alpha. An article of manufacture comprising...
US20150023910 GRANULYSIN IN IMMUNOTHERAPY  
Methods of stimulating or enhancing an immune response in a host are disclosed. The methods include contacting a monocyte with 15 kD granulysin thereby producing a monocyte-derived dendritic cell....
US20140234423 PROGRAMMING OF CELLS FOR TOLEROGENIC THERAPIES  
Biomaterial systems, e.g., gel scaffolds, are used in vivo to recruit immune cells and promote their activation towards a non-inflammatory phenotype, thereby leading suppression of inflammation....
US20110150824 Nutritional Composition for Improving the Mammalian Immune System  
The invention relates to a nutritional composition comprising (a) at least 18 en % of proteinaceous matter;(b) at least 12 wt % of leucine, based on total proteinaceous matter;(c) a lipid fraction...
US20150196636 IMMUNOREGULATORY VACCINE  
An immune-regulatory vaccine comprising—a directed adjuvant comprising at least an anti-CD32 moiety linked to a TLR9 ligand and a first peptidic alpha-helix, and—an immunogen with at least one...
US20110311536 PREVENTION OF TYPE 1 DIABETES BY TREG VACCINATION WITH AN INSULIN MIMETOPE  
The invention involves methods and products for inducing Treg cells for immune suppression in connection with autoimmune disease and transplant rejection.
US20140065184 HLA-G Isoform for use in the Treatment of a Disease Associated with Bone Resorption  
Novel use of HLA-G isoforms in the treatment or prevention of diseases in which bone resorption is observed.
US20130309267 CANCER IMMUNOTHERAPY COMPOSITIONS AND METHODS OF USE  
Cellular compositions and methods for inducing an immune response to tumor cells are described. The cellular compositions include a tumor antigen and cells that have been modified to express a...
US20120076831 COMPOSITIONS AND METHODS FOR INDUCTION OF ANTIGEN-SPECIFIC TOLERANCE  
The present invention utilizes carrier particles to present antigen peptides and proteins to the immune system in such a way as to induce antigen specific tolerance. The carrier particle is...
US20150140007 PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING TYPE I DIABETES AND APPLICATION THEREOF  
The present invention provides a composition for treating and/or preventing type I diabetes and an application thereof. The active ingredient of the composition is 1.) or 2.) or 3.), as follows:...
US20100136046 RECOMBINANT POLYPROTEIN VACCINES FOR THE TREATMENT AND DIAGNOSIS OF LEISHMANIASIS  
Compositions and methods for preventing, treating and detecting leishmaniasis are disclosed. The compositions generally comprise fusion polypeptides comprising multiple Leishmania antigens, in...
US20150110805 THERAPEUTIC STRATEGY FOR TREATING AUTOIMMUNE AND DEGENERATIVE DISEASES  
Numerous diseases have been linked to the production of effector cells. The present invention relates to the realization that effector cells are cycling in these diseases. In addition, the present...
US20090081157 Immunostimulatory Combinations for Vaccine Adjuvants  
This invention discloses immunostimulatory combinations of Tumor Necrosis Factor Receptor Superfamily (TN-FRSF) agonists, Toll-Like Receptor (TLR) agonists, “domain present in NAIP, CIITA, HET-E,...
US20070280959 Use Of Platelets Or Platelet Rich Plasma(Prp)  
A new use is disclosed for the content of platelets or platelet rich plasma (PRP) obtained by disruption of their membranes for the preparation of an agent for the treatment of bone, cartilage or...
US20140294889 USE OF THE PACAP AS A MOLECULAR ADJUVANT FOR VACCINES  
The present invention relates to the use of the pituitary adenylate cyclase activating peptide (PACAP) as a molecular adjuvant for vaccines. Among other applications, these vaccines may be used in...
US20140178334 Methods and compositions for liquidation of tumors  
This invention relates to compositions and methods for immunotherapy of cancer. Specifically, a method of cancer immunotherapy is described which results in the systemic liquidation of both solid...
US20110142887 Methods and compositions for liquidation of tumors  
This invention relates to compositions and methods for immunotherapy of cancer. Specifically, a method of cancer immunotherapy is described which results in the systemic liquidation of both solid...
US20090110693 MULTIMERIC COMPLEXES OF ANTIGENS AND AN ADJUVANT  
The invention relates to a product which comprises a C4bp domain of a non-mammalian origin, particularly SEQ ID NO:1, SEQ ID NO:23 or SEQ ID NO:37, or a variant thereof, and an antigen. The...
US20130273001 IMMUNOSTIMULATION BY CHEMICALLY MODIFIED RNA  
The present invention relates to an immunostimulating agent comprising at least one chemically modified RNA. The invention furthermore relates to a vaccine which comprises at least one antigen in...
US20120003225 AUTOANTIBODIES IN THE DETECTION AND TREATMENT OF CANCER  
Methods, kits, and compositions for detecting and/or treating cancer based on detecting and/or administering an antibody, which can optionally be a bispecific antibody, having the immunoreaction...
US20120128688 ANTI-CXCL13 AND ANTI-CXCR5 ANTIBODIES FOR THE PREVENTION AND TREATMENT OF CANCER AND CANCER CELL MIGRATION  
Methods for prevention or inhibition of the growth or metastasis of cancer cells in a subject are disclosed. One method comprises the step of administering to the subject a therapeutically...
US20080187536 Immunological modulation of insulin-like growth factor 1 for cancer prevention/treatment and prolonging longevity  
Provided is a simple and safe immunization procedure to reduce cancer incidence and increase longevity by modulating IGF-1 levels in the body. Described are cancer preventive vaccines and methods...
US20130101597 MODULATION OF NK CELL ANTIGEN SPECIFIC EFFECTOR ACTIVITY BY MODULATION OF CXCR6 (CD186)  
The instant invention is based, at least in part, on the discovery that CXCR6 plays a critical role in antigen-specific effector function of NK cells. Accordingly, the invention provides, among...
US20120171242 Modified Antibody  
Recombinant antibody-based molecules that trigger both T-cell and B-cell immune responses are disclosed. The recombinant molecules are comprised by at least one targeting unit and at least one...
US20110300104 HEPATITIS C VIRUS INHIBITORS  
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit RNA-containing virus, particularly the Hepatitis C Virus...
US20140178400 T-Helper Cell Type 17 Lineage-Specific Adjuvants, Compositions and Methods  
The present invention relates to compositions and methods for modulation of TH17 responses. The invention provides compositions for the induction of TH17 responses containing a TLR agonist and an...
US20120130144 TREATMENT OF LUNG CANCER WITH A NITROBENZAMIDE COMPOUND IN COMBINATION WITH A GROWTH FACTOR INHIBITOR  
In one aspect, the present invention provides a method of treating lung cancer, comprising administering to a subject at least one PARP inhibitor in combination with at least one growth factor...
US20130058970 INDUCED TOLEROGENIC DENDRITIC CELLS TO REDUCE SYSTEMIC INFLAMMATORY CYTOKINES  
Disclosed are induced tolerogenic dendritic cells (itDCs), as well as related compositions and methods, for reducing systemic inflammatory cytokines.
US20100021496 METHODS, KITS, AND ANTIBODIES FOR QUANTITATIVE DETERMINATION OF PARATHYROID HORMONE MOLECULES WITH INTACT C-TERMINUS  
The present invention relates to novel methods and compositions useful for detecting whole parathyroid hormone at a physiological level and C-terminal parathyroid fragments in a mammalian sample....
US20080220013 Diagnostic Method for Brain Damage-Related Disorders  
A brain damage-related disorder is diagnosed in a subject by detecting at least one polypeptide, or a variant or mutant thereof, in a sample of body fluid taken from the subject, wherein the...
US20100143401 VACCINE PREVENTING AND/OR TREATING AUTOIMMUNE DISEASES  
The present invention discloses a vaccine preventing and/or treating autoimmune diseases. Its active component is: the mixture consisting of a protein antigen causing an autoimmune disease or the...
US20070212372 Methods for the treatment and prophylaxis of demeyelinating disease  
The present invention relates to a method for the treatment and/or prophylaxis of a nervous system disease, demyelinating disease and/or an inflammatory disease of either the central or peripheral...
US20100330088 STRATEGIES TO PREVENT AND/OR TREAT IMMUNIE RESPONSES TO SOLUBLE ALLOFACTORS  
The present invention relates to the use of immunogenic peptides comprising a T-cell epitope derived from a soluble allofactor and a redox motif such as C-(X)2-[CST] or [CST]-(X)2-C in the...
US20080187543 Use of Myostatin (Gdf-8) Antagonists for Improving Wound Healing and Preventing Fibrotic Disease  
The present invention relates to a method of improving wound healing in a human or animal patient by inhibiting the activity of myostatin (GDF-8) using one or more myostatin antagonists. The...
US20060287227 Gonadal function improving agents  
Metastin, compounds that promote the activity of metastin or its receptors and the like are excellent gonadal function improving agents, ovulation inducers or promoters, gonadotropic hormone...

Matches 1 - 50 out of 79 1 2 >