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US20160002318 HUMAN BINDING MOLECULES CAPABLE OF BINDING TO AND NEUTRALIZING INFLUENZA B VIRUSES AND USES THEREOF  
Described are binding molecules, such as human monoclonal antibodies, that bind to hemagglutinin of influenza B viruses, and have a broad neutralizing activity against such influenza viruses....
US20140205614 NEUTRALIZING ANTIBODIES TO INFLUENZA VIRUSES  
The present invention concerns methods and means for identifying, producing, and engineering neutralizing antibodies against influenza A viruses, and to the neutralizing antibodies produced. In...
US20120107326 NEUTRALIZING ANTIBODIES TO INFLUENZA VIRUSES  
The present invention concerns methods and means for identifying, producing, and engineering neutralizing antibodies against influenza A viruses, and to the neutralizing antibodies produced. In...
US20110182857 Delivery of Drugs to Mucosal Surfaces  
Liquid pharmaceutical compositions for administration to a mucosal surface, including a therapeutic agent and a pectin with a low degree of esterification are described. Such compositions gel, or...
US20100316654 NEUTRALIZING ANTIBODIES TO INFLUENZA VIRUSES  
The present invention concerns methods and means for identifying, producing, and engineering neutralizing antibodies against influenza A viruses, and to the neutralizing antibodies produced. In...
US20080014205 Neutralizing Antibodies to Influenza Viruses  
The present invention concerns methods and means for identifying, producing, and engineering neutralizing antibodies against influenza A viruses, and to the neutralizing antibodies produced. In...
US20070082002 Neutralizing High Affinity Human Monoclonal Antibodies Specific to RSV F-Protein and Methods for their Manufacture and Therapeutic use thereof  
A highly efficient method for generating human antibodies in particular which are specific to be RSV fusion protein which combines in vitro primary of human spleen cells and antigen boosting in...
US20160193321 MAKING INFLUENZA VIRUS VACCINES WITHOUT USING EGGS  
Currently, the steps performed prior to release of influenza strains to vaccine manufacturers involve passaging influenza virus through eggs. The invention aims to provide procedures useful in...
US20160166692 RNA-CODED ANTIBODY  
The present application describes an antibody-coding, non-modified or modified RNA and the use thereof for expression of this antibody, for the preparation of a pharmaceutical composition, in...
US20100266614 ULTRA HIGH AFFINITY NEUTRALIZING ANTIBODIES  
Ultra high affinity antibodies with binding affinities in the range of 1010 M−1, and even 1011 M−1 are disclosed. Such antibodies include antibodies having novel high affinity complementarity...
US20070224205 Compositions that include hemagglutinin, methods of making and methods of use thereof  
Compositions comprise a flagellin component or a Toll-like Receptor agonist component that is at least a portion of a flagellin or a Toll-like Receptor agonist, wherein the flagellin component or...
US20170136118 NEUTRALIZING MOLECULES TO VIRAL ANTIGENS  
The present invention concerns methods and means for identifying, producing, and engineering neutralizing molecules against influenza A viruses, and to the neutralizing molecules produced. In...
US20110189171 RECOMBINANT ANTIBODIES FOR TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS INFECTIONS  
Disclosed are novel polyclonal antibodies, which target respiratory syncytial virus (RSV), as well as novel high affinity antibody molecules reactive with RSV. The polyclonal antibodies may...
US20110027294 Anti-Respiratory Syncytial Virus Antibodies, Antigens and Uses Thereof  
Anti-Respiratory Syncytial Virus (RSV) monoclonal antibodies, RSV F protein antigens and their uses are disclosed.
US20100172917 Binding molecules against SARS-coronavirus and uses thereof  
Described are binding molecules that specifically bind to SARS-CoV, nucleic acid molecules encoding the binding molecules, compositions comprising the binding molecules, and methods of identifying...
US20100040635 NEUTRALIZING ANTIBODIES TO INFLUENZA VIRUSES  
The present invention concerns methods and means for identifying, producing, and engineering neutralizing molecules against influenza A viruses, and to the neutralizing molecules produced. In...
US20090175883 Stabilized anti-respiratory syncytial virus (RSV) antibody formulations  
The present invention provides liquid formulations of antibodies or fragments thereof that immunospecifically bind to a respiratory syncytial virus (RSV) antigen, which formulations exhibit...
US20070009512 Recombinant bivalent monospecific immunoglobulin having at least two variable fragments of heavy chains of an immunoglobulin devoid of light chains  
The present invention relates to fragments, especially variable fragments of immunoglobulins which are by nature devoid of light chains, these fragments being nevertheless capable of exhibiting a...
US20140227290 METHOD FOR INCREASING N-GLYCOSYLATION SITE OCCUPANCY ON THERAPEUTIC GLYCOPROTEINS PRODUCED IN PICHIA PASTORIS  
Described is a method for increasing the N-glycosylation site occupancy of a therapeutic glycoprotein produced in recombinant host cells modified as described herein and genetically engineered to...
US20100266668 Manufacturing Dissolvable Dosage Forms  
A method of manufacturing a dosage form is described wherein a liquid solution of a biologically compatible polymer containing a suspension of particulate material that is insoluble in the polymer...
US20070110757 Antibody formulations having optimized aggregation and fragmentation profiles  
The present invention provides methods of optimizing the production and purification of antibody formulations that immunospecifically bind to antigens of interest and are suitable for parenteral...
US20120177650 THERAPY FOR ENTERIC INFECTIONS  
A method and composition for treating enteric pathogen infections in animals suffering from such infections or displaying diseases or conditions consistent with such infections or for preventing...
US20070224204 Combination therapy of respiratory diseases using antibodies and anti-inflammatory agents  
Therapeutically effective anti-viral compositions, useful especially against respiratory diseases caused or mediated by respiratory syncytial virus (RSV) are disclosed, wherein said compositions...
US20120135006 ULTRA HIGH AFFINITY NEUTRALIZING ANTIBODIES  
Ultra high affinity antibodies with binding affinities in the range of 1010 M−1, and even 1011 M−1 are disclosed. Such antibodies include antibodies having novel high affinity complementarity...
US20070092523 Combination Therapy Of Respiratory Diseases Using Antibodies  
Therapeutically effective anti-microbial compositions, useful especially against respiratory diseases caused or mediated by viruses, bacteria, and other respiratory parasites are disclosed,...
US20070065452 THERAPEUTIC ANTIBODIES FOR TREATMENT AND PROPHYLAXIS OF TRANSMITTABLE VIRAL DISEASES  
The invention provides methods and compositions for the treatment and prevention of a transmittable disease in a subject, such as avians and mammals. The methods and compositions of the invention...
US20050112130 Enhanced B cell cytotoxicity of CDIM binding antibody  
Formulations and methods of treating human patients suffering from a condition characterized by lymphoid cancer, autoimmune disease or B cell hyperproliferation are disclosed, the treatment...
US20130039926 HUMAN ANTIBODIES AGAINST RABIES AND USES THEREOF  
Human monoclonal antibodies that specifically bind to rabies virus, antigen binding portions thereof, and methods of making and using such antibodies and antigen binding portions thereof for...
US20060198848 Methods and compositions for treating herpes infections  
A method of treatment or prophylaxis of herpes infections and associated disease states by administration of compositions comprising immunoglobulins. Methods comprising intravenous and topical...
US20060002862 High pressure spray-dry of bioactive materials  
This invention provides compositions and methods providing, e.g., stable powder particles containing bioactive materials. The methods include, e.g., high pressure spraying of the bioactive...
US20130243773 RECOMBINANT PRODUCTION OF MIXTURES OF ANTIBODIES  
Provided is methods for producing mixtures of antibodies from a single host cell clone, wherein, a nucleic acid sequence encoding a light chain and nucleic acid sequences encoding different heavy...
US20130202617 HEMORRHAGIC FELINE CALICIVIRUS, CALICIVIRUS AND METHOD FOR PREVENTING CALICIVIRUS INFECTION OR DISEASE  
The present invention relates to a novel, isolated and purified hemorrhagic feline calicivirus FCV-DD1. The invention further embraces monovalent and multivalent vaccines containing the new...
US20120114664 ANTIBODIES AGAINST H5N1 STRAINS OF INFLUENZA A VIRUS  
Provided are human antibodies that can neutralize a H5N1 strain of influenza A virus. Also provided are antibodies that can neutralize a strain of influenza A virus in clade 2 of the H5 subtype,...
US20120082666 ANTIBODY COMPOSITIONS AND METHODS OF USE  
The invention provides compositions comprising anti-gH antibodies and anti-Complex I antibodies as well as methods of using the same.
US20110081347 Antibodies with Altered Binding to FcRn and Methods of Using Same  
This invention relates to antibodies with altered binding to FcRn, and particularly antibodies having enhanced binding to FcRn and/or enhanced serum half-lives. The invention also relates to...
US20100040606 Recombinant polyclonal antibody for treatment of respiratory syncytial virus infections  
Disclosed are novel polyclonal antibodies, which target respiratory syncyticilal virus (RSV), and novel high affinity antibody molecules reactive with RSV. The polyclonal antibodies may comprise...
US20160130275 PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT  
The invention provides compounds of Formula I or Formula II: or a pharmaceutically acceptable salt or ester, thereof, as described herein. The compounds and compositions thereof are useful for...
US20130034500 Cationic Steroid Antimicrobial Compositions and Methods of Use  
The invention provides methods for decreasing or inhibiting herpesviridae (HV) infection or pathogenesis of a cell in vitro, ex vivo or in vivo, a symptom or pathology associated with a...
US20120070447 METHODS OF ADMINISTERING / DOSING ANTI-RSV ANTIBODIES FOR PROPHYLAXIS AND TREATMENT  
The present invention encompasses novel antibodies and fragments thereof which immunospecifically bind to one or more RSV antigens and compositions comprising said antibodies and antibody...
US20100215667 METHODS AND COMPOSITIONS OF TREATMENT FOR MODULATING THE IMMUNE SYSTEM OF ANIMALS  
Methods and compositions are disclosed for the dietary modulation of the immune system and gut microbial response in animals. Applicant has identified that oral administration of a supplemental...
US20050281828 Method of treating autoimmune disease by inducing antigen presentation by tolerance inducing antigen presenting cells  
Antibodies to antigen presenting cells may be utilized to interfere with the interaction of the antigen presenting cell and immune cells, including T cells. Peptides may be linked to said...
US20120269811 HUMANIZED FC GAMMA RIIB-SPECIFIC ANTIBODIES AND METHODS OF USE THEREOF  
The present invention relates to humanized FcγRIIB antibodies, fragments, and variants thereof that bind human FcγRIIB with a greater affinity than said antibody binds FcγRIIA. The invention...
US20120128671 NEUTRALIZING MOLECULES TO INFLUENZA VIRUSES  
The present invention concerns methods and means for identifying, producing, and engineering neutralizing antibodies against influenza A viruses, and to the neutralizing antibodies produced. In...
US20120014972 INFLUENZA VIRUS COMPOSITIONS AND METHODS FOR UNIVERSAL VACCINES  
The disclosure relates at least in part to embodiments of compositions and methods including vaccines for protection against multiple serologically distinct strains of influenza virus. This...
US20080187546 Method for Replicating Influenza Virus in Culture  
The invention is related to a method for selecting an influenza virus for growth on tissue culture cells to produce a tissue-culture adapted viral isolate. The invention also includes vaccines...
US20080107652 Methods and compositions for control of disease in aquaculture  
The invention discloses paratransgenesis methods for prevention, amelioration or treatment of a disease or disorder in an aquatic animal. The method comprises providing a genetically modified...
US20080019979 HERV-K Antigens, Antibodies, and Methods  
Methods and compositions for cancer diagnostics and therapy are provided. More particular, methods and compositions for detecting, preventing, and treating HERV-K+ cancers are provided. One...
US20070196274 Immunoconjugates with improved efficacy for the treatment of diseases  
The invention provides therapeutic or diagnostic antibodies with modified N— or C-terminal sequences that are enriched with lysine or tyrosine residues. These lysine or tyfosine residues can be...
US20060257411 Compositions and methods for modulating cells via CD14 and toll-like receptor 4 signaling pathway  
Compositions and methods are provided for screening and identifying compounds which modulate signaling of toll-like receptor 4 (TLR4) pathway via CD14 and a ligand. Methods are provided for...
US20060115485 Methods of preventing and treating RSV infections and related conditions  
The present invention provides methods for preventing, managing, treating and/or ameliorating a Respiratory Syncytial Virus (RSV) infection (e.g., acute RSV disease, or a RSV upper respiratory...
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