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US20120046185 PANEL OF BIOMARKERS FOR OVARIAN CANCER  
The present invention provides a panel of protein-based biomarkers that are useful in diagnosing ovarian cancer in a subject. In particular, the panel of biomarkers of the invention are useful to...
US20110065130 Diagnosing and Grading Gliomas Using a Proteomics  
The present invention provides for a proteomic approach to grading gliomas, and for predicting patient survival. In addition to employing global protein expression patterns, such as by mass...
US20150097113 Modulation of Instrument Resolution Dependant upon the Complexity of a Previous Scan  
Systems and methods are used to analyze a sample using variable detection scan resolutions. A tandem mass spectrometer is instructed to perform at least two scans of a sample with different...
US20130020482 METHOD FOR ENHANCEMENT OF MASS RESOLUTION OVER A LIMITED MASS RANGE FOR TIME-OF-FLIGHT SPECTROMETRY  
Novel methods and instrumentation for mass spectrometry are described. Zoom-time of flight mass spectrometry (Zoom-TOF) allows increased mass resolution over a pre-determined specific range of...
US20110315866 Forward and Reverse Scanning for a Beam Instrument  
A quadrupole mass spectrometer alternates between increasing mass and decreasing mass scans for the purpose of decreasing inter-scan delays. By alternating increasing and decreasing mass scans,...
US20120145891 Using Plasma Proteomic Pattern For Diagnosis, Classification, Prediction Of Response To Therapy And Clinical Behavior, Stratification Of Therapy, And Monitoring Disease In Hematologic Malignancies  
The present invention demonstrates that the diagnosis and prediction of clinical behavior in patients with hematologic malignancies, such as leukemia, can be accomplished by analysis of proteins...
US20150153348 BIOMARKERS FOR OVARIAN CANCER: Beta 2 MICROGLOBULIN  
The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying ovarian cancer status in a patient. In particular, the biomarkers of this invention...
US20140020447 TRACE ANALYTE EXTRACTION USING ADSORPTIVE CARBIDE-DERIVED NANOPOROUS CARBON POWDERS  
In the method of latent print analysis, wherein the improvement comprises using an ultra-fine, nanoporous carbon material as an adsorptive powder to identify trace chemicals found within oils of a...
US20120295288 SEROLOGICAL MARKER FOR DETECTING PANCREATIC CANCER AND A METHOD FOR USING THE SEROLOGICAL MARKER  
UL16 binding protein 2 (ULBP2) is a protein overexpressed in pancreatic cancer tissues, and the ULBP2 levels are significantly higher in pancreatic cancer patients than those in healthy controls....
US20120087862 ORGAN-SPECIFIC PROTEINS AND METHODS OF THEIR USE  
The present invention relates generally to methods for identifying and using organ-specific proteins and transcripts. The present invention further provides compositions comprising organ-specific...
US20110226942 COMPOSITIONS, KITS, AND METHODS FOR CALIBRATION IN MASS SPECTROMETRY  
The invention provides compositions, kits, and methods for calibrating a mass spectrometer using two or more recombinant proteins and one or more energy-absorbing molecules. The recombinant...
US20110111512 QUANTITATION OF INSULIN-LIKE GROWTH FACTOR-I AND INSULIN-LIKE GROWTH FACTOR-II WITH HIGH-RESOLUTION MASS SPECTROMETRY  
Methods are provided for determining the amount of an IGF-I and/or IGF-II protein in a sample using high resolution/high accuracy mass spectrometry. The methods generally comprise enriching an...
US20150031048 CITRULLINATED BRAIN AND NEUROLOGICAL PROTEINS AS BIOMARKERS OF BRAIN INJURY OR NEURODEGENERATION  
The present invention relates to the field of biomarkers. More specifically, the present invention relates to biomarkers useful in diagnosing brain injury or neurodegeneration. In one embodiment,...
US20110300641 PROTEIN ISOFORMS FOR DIAGNOSIS  
Several aspects of this invention relate to diagnosis of diabetic states in a mammal using protein isoforms. In some aspects, it relates to a method for determining the diabetic state of a mammal....
US20140260974 CAPILLARY MICROEXTRACTOR OF VOLATILES (CMV)  
A capillary microextractor of volatiles (CMV) allows the sampling of diagnostic volatiles that can be an explosive, explosive taggant, drug, poison, decomposition products thereof, a mixture of...
US20130330746 BIOMARKERS USEFUL FOR DIAGNOSING PROSTATE CANCER, AND METHODS THEREOF  
The present invention describes a method for predicting a health-state indicative of the presence of prostate cancer. The method measures the intensities of specific small biochemicals, called...
US20130140452 MEANS AND METHODS FOR DIAGNOSING PANCREATIC CANCER IN A SUBJECT  
The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing pancreatic cancer in a subject, a method for identifying...
US20130037707 MEASUREMENT OF ISOTOPE RATIOS IN COMPLEX MATRICES  
The present techniques are directed to a method for microprobe analyses of isotope ratios in inhomogeneous matrices. The method includes selecting matrix standards that have matrices that resemble...
US20110127416 Mass Spectrometer  
A mass spectrometer is disclosed comprising a sampling cone (3) and a cone-gas cone (4) wherein, in use, sulphur hexa fluoride (‘SF6’) is supplied as a cone gas (5) to the annulus between the...
US20130161502 METHOD FOR ANALYSIS OF THE CHEMICAL COMPOSITION OF THE HEAVY FRACTION OF PETROLEUM  
The chemical composition of petroleum samples is measured using orbitrap mass spectrometry with electrospray ionization (ESI). The orbitrap measurement is used in a screening to determine if one...
US20140308687 Method and Use of Metabolites for the Diagnosis and Differentiation of Neonatal Encephalopathy  
Metabolites and signatures (panels) of metabolites are applicable as biomarkers in clinical diagnosis, in particular for neonatal encephalopathy. They are useful tools in differential clinical...
US20110001042 ASSESSING TREATMENT COMPLIANCE  
This document provides methods and materials related to determining whether or not a mammal is receiving a steroid treatment. For example, methods and materials involved in assessing a biological...
US20120164663 Methylated Arginine Metabolites as Risk Predictors of Cardiovascular Disease  
Methods for using methylated arginine metabolites and the arginine methylation index as markers for cardiovascular disease are described: The methods typically include determining the levels of...
US20110207627 EX VIVO THERAPEUTICS SCREENING OF LIVING BONE MARROW CELLS FOR MULTIPLE MYELOMA  
Methods of selecting a treatment for a patient with multiple myeloma are provided. Prior to commencing a treatment regime, bone marrow aspirates are isolated from a patient and incubated with one...
US20110297543 Autosomal-Dominant Polycystic Kidney Disease (ADPKD)  
The process for the diagnosis, early detection and prognosis of the clinical development of autosomal-dominant polycystic kidney disease (ADPKD) comprises the step of determining the presence or...
US20120089343 DETECTION OF ETHANOL EMISSION FROM A SPARK IGNITION ENGINE OPERATING ON GASOHOLS  
Ethanol emissions from a direct ignition spark ignition are measured using mass spectrometry. The method exploits specific fragment ions from ethanol. Ethanol contributes ions of mass number 31,...
US20110229983 MARKING FUEL FOR AUTHENTICATION  
A first fuel and a second fuel are marked with a marker that can be detected quantitatively in a predetermined concentration range. The second fuel is marked with a binary marker. Decreased...
US20130277550 Mass Spectrometer Sampling Cone With Coating  
A sampling cone of a mass spectrometer is disclosed having a metallic boride coating such as titanium diboride.
US20120037507 METHOD AND MARKER FOR DIAGNOSIS OF TUBULAR KIDNEY DAMAGE AND ILLNESSES  
A method for the diagnosis of tubular kidney diseases comprising the step of determining the presence or absence or amplitude of at least three polypeptide markers in a urine sample, the...
US20110036717 METHOD AND MARKER FOR DIAGNOSIS OF TUBULAR KIDNEY DAMAGE AND ILLNESS  
A method for the diagnosis of tubular kidney diseases comprising the step of determining the presence or absence or amplitude of at least three polypeptide markers in a urine sample, the...
US20110214990 KIDNEY CELL CARCINOMA  
The process for the diagnosis of a renal cell carcinoma comprises the step of determining the presence or absence or amplitude of at least three polypeptide markers in a urine sample, wherein said...
US20140274956 LIPIDOMICS OF FAMILIAL LONGEVITY  
The disclosure relates to method of typing a sample from an individual as a sample from an individual with an increased life expectancy, an average life expectancy or a reduced life expectancy....
US20140255983 METHOD OF CANCER DIAGNOSIS USING THE ANALYSIS OF ISOTOPES  
Disclosed is a method of diagnosing cancer on the basis of the quantitative analysis of blood or tissue isotopes, for example, such as 36S or 40K. The method can accurately diagnose cancer in a...
US20140255982 METHOD OF CANCER DIAGNOSIS USING THE ANALYSIS OF ISOTOPES  
Disclosed is a method of diagnosing cancer on the basis of the quantitative analysis of blood or tissue isotopes, for example, such as 36S or 40K. The method can accurately diagnose cancer in a...
US20140255981 METHOD OF CANCER DIAGNOSIS USING THE ANALYSIS OF ISOTOPES  
Disclosed is a method of diagnosing cancer on the basis of the quantitative analysis of blood or tissue isotopes, for example, such as 36S or 40K. The method can accurately diagnose cancer in a...
US20120331573 DYNACTIN SUBUNIT p62 BIOMARKER FOR NEUROLOGICAL CONDITIONS  
Methods and kits for identifying neurological conditions in a patient by determining a level of expression of dynactin subunit p62 are disclosed. The neurological conditions may include, for...
US20120118737 Method And Markers For Diagnosing Acute Renal Failure  
The invention relates to a method for diagnosing acute renal failure, comprising the step of determining a presence or absence or amplitude of at least three polypeptide markers in a sample,...
US20140175275 MASS SPECTROMETRY ASSAY FOR CONGENITAL ADRENAL HYPERPLASIA  
Methods are provided for detecting the amount of one or more CAH panel analytes (i.e., pregnenolone, 17-OH pregnenolone, progesterone, 17-OH progesterone, dehydroepiandrosterone (DHEA),...
US20140014832 MASS SPECTROMETRY ASSAY FOR CONGENITAL ADRENAL HYPERPLASIA  
Methods are provided for detecting the amount of one or more CAH panel analytes (i.e., pregnenolone, 17-OH pregnenolone, progesterone, 17-OH progesterone, dehydroepiandrosterone (DHEA),...
US20130206981 MASS SPECTROMETRY ASSAY FOR CONGENITAL ADRENAL HYPERPLASIA  
Methods are provided for detecting the amount of one or more CAH panel analytes (i.e., pregnenolone, 17-OH pregnenolone, progesterone, 17-OH progesterone, dehydroepiandrosterone (DHEA),...
US20120228487 MASS SPECTROMETRY ASSAY FOR CONGENITAL ADRENAL HYPERPLASIA  
Methods are provided for detecting the amount of one or more CAH panel analytes (i.e., pregnenolone, 17-OH pregnenolone, progesterone, 17-OH progesterone, dehydroepiandrosterone (DHEA),...
US20120018629 MECHANICAL HOLDER FOR SURFACE ANALYSIS  
A mechanical holder that provides for a confined sampling region for extraction and removal of chemical substances contained in a dried blood spot or other spot of sample is described herein.
US20120138784 Method for in Vivo Measurement of Reverse Cholesterol Transport  
Methods and compositions for the in vivo measurement of reverse cholesterol transport are provided.
US20120085903 MASS SPECTOMETRY USING LASERSPRAY IONIZATION  
Disclosed herein are systems and methods for mass spectrometry using laserspray ionization (LSI). LSI can create multiply-charged ions at atmospheric pressure for analysis and allows for analysis...
US20140103204 Biomarkers for the Diagnosis and Treatment of Pancreatic Cancer  
Compositions and methods which indicate an increased risk for pancreatic carcinoma are disclosed.
US20130280820 BIOMARKERS FOR PSORIASIS  
A group of polypeptides that are modulated in a psoriatic sample as compared to a normal sample is provided. These polypeptides can be used as biomarkers for diagnosis and monitoring treatment of...
US20140183350 Compact Mass Spectrometer  
Mass spectrometers and methods for measuring information about samples using mass spectrometry are disclosed.
US20120064091 DYSFUNCTION OF THE MITOCHONDRIAL RESPIRATORY CHAIN, METHODS FOR DIAGNOSIS, TREATMENT AND FOLLOW-UP  
The invention relates to a method, of assessing whether a subject is affected with or at risk for developing a dysfunction of the mitochondrial respiratory chain, the method comprising determining...
US20100301199 Ultrasound ionization mass spectrometer  
Methods and systems for ultrasound ionization mass spectrometry are provided. Analytes in a sample are ionized by subjecting them to ultrasound, facilitating their analysis by mass spectrometry....
US20120164671 METHODS FOR MONITORING IMMUNOSUPPRESSANT DRUG LEVELS, RENAL FUNCTION, AND HEPATIC FUNCTION USING SMALL VOLUME SAMPLES  
Systems and methods are provided for monitoring a immunosuppressant drug level and renal function, hepatic function, or a combination thereof in a patient, comprising obtaining a small volume...