Title:
3-naphthyloxy-2-hydroxypropylamines
United States Patent 3337628


Abstract:
(A) Cmpds. of the general formula R1 = H or opt. subst. alkyl, cycloalkyl, alkenyl, aralkyl or alkanoyl; R2 = H or opt. subst. alkyl, cycloalkyl, alkenyl, alkynyl or aralkyl or R1 and R2 may, together with the N atom, form an opt. subst. heterocyclic ring; R3, R4 and R5 = H or alkyl. (B) Esters of (I). (C) Salts of (I). Adrenergic blocking agent useful in the treatment of cardiac dysfunction (see Derwent 12,733).



Inventors:
Frederick, Crowther Albert
Harold, Smith Leslie
Application Number:
US32308963A
Publication Date:
08/22/1967
Filing Date:
11/12/1963
Assignee:
ICI LTD
Primary Class:
Other Classes:
544/174, 548/575, 549/551, 560/107, 560/221, 560/251, 560/252, 564/86, 564/219, 568/312, 568/328, 568/633
International Classes:
C07C51/60; C07C59/66; C07D295/092
View Patent Images:
Foreign References:
FR1198123A1959-12-04
GB622297A1949-04-29