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8110654 |
T cell epitope peptides of ovarian cancer anti-idiotypic antibody 6B11 and use thereof
The present invention provides two T-cell epitode peptides of anti-idiotype antibody 6B11 of ovarian cancer, the sequences of which are shown in SEQ ID NO:3 or 6. The present invention also...
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8110550 |
HDAC inhibitors and hormone targeted drugs for the treatment of cancer
The present invention relates to the methods of treating endocrine-regulated cancers, including hormone resistant cancers, for example. More specifically, the present invention relates to a method...
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8110544 |
RasGAP derived peptide for selectively killing cancer cells
The present invention relates to a peptide consisting in the N2 sequence of the RasGAP protein, a fragment thereof, or a variant thereof which enhances the ability of a drug to selectively kill...
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8110375 |
High throughput assay for cancer cell growth inhibition
A high-throughput, anchorage-independent assay is described, which screens compounds for inhibition of cancer cell growth. The assay utilizes a three-dimensional matrix or semi-solid media...
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8110370 |
IBC-1 (Invasive Breast Cancer-1), a putative oncogene amplified in breast cancer
This invention encompasses antibodies specific for IBC-1 (Invasive Breast Cancer-1), methods for diagnosis and prognosis of metastatic breast cancer and degenerative neural conditions, methods of...
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8110363 |
Expression profiles to predict relapse of prostate cancer
The present invention provides a method for preparing a reference model for cancer relapse prediction that provides higher resolution grading than Gleason score alone. The method encompasses...
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8110362 |
Method for determining a tongue cancer
An object is to provide: a method for determining a tongue cancer in which the malignancy of tongue cancer can be objectively and accurately determined; a method for analyzing a tongue cancer...
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8110361 |
DNA methylation markers associated with the CpG island methylator phenotype (CIMP) in human colorectal cancer
Particular aspects confirm the existence of a CpG island methylator phenotype (CIMP) in colorectal cancer, and provide novel validated DNA methylation markers associated with CIMP. Additional...
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8110358 |
Method of profiling gene expression in a subject having prostate cancer
The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and...
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8110352 |
Method of diagnosing and treating cancer using B-catenin splice variants
The invention relates to method of diagnosing and treating cancer, in particular β-catenin related cancers. The invention further relates to methods of identifying CTNNB1 related cancer CTNNB1 ...
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8110347 |
Diagnostic method for detecting cancer by measuring amount of cytokine like IL-6
The present invention relates to a diagnostic method for predicting the possible recurrence of tumors in cancer patients. The method comprises culturing blood cells from a patient suffering from...
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8106024 |
Method of treating cancer with an RPN2 gene expression inhibitor
The present invention uses an RPN2 gene expression inhibitor as a cancer cell growth inhibitor, which further includes a drug showing an anti-cancer action if desired, and is administered in...
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8106002 |
Anti-cancer agent comprising protein C inhibitor
The present invention provides anti-cancer agents comprising protein C inhibitor (PCI) or derivatives thereof as an active ingredient. The anti-cancer agents of the present invention have...
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8105777 |
Methods for diagnosis and/or prognosis of colon cancer
The present invention relates to genetic markers whose expression is correlated with colon cancer. In one aspect, the invention provides sets of markers whose expression can be used for classifying...
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8105773 |
Oligonucleotides for cancer diagnosis
The present invention provides sets of oligonucleotides corresponding to genes encoding proteins involved in protein synthesis and/or stability or genes encoding proteins involved in the regulation...
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8105769 |
Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments
The present invention is directed to a method for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) treatment. In a preferred embodiment, the presence of at...
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8105615 |
Lactoferrin as an adjuvant in cancer vaccines
The present invention relates to methods of treating cancer by administering a composition of lactoferrin (LF) in combination with cancer vaccines.
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8101773 |
Hydroxy methyl phenyl pyrazolyl urea compounds useful in the treatment of cancer
The compound 4-{4-[({3-tert-Butyl-1-[3-(hydroxymethyl)phenyl]-1H-pyrazol-
5-yl}carbamoyl)amino]-3-fluorophenoxy}-N-methylpyridine-2-ca
rboxamide and alternative forms thereof (e.g., salts,...
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8101713 |
Prostate cancer diagnosis and treatment
The present invention relates to novel antibodies and their use for detecting, imaging, staging, treating and monitoring of prostate cancer, and/or metastasis thereof. The present invention also...
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8101662 |
Treatment of cancer with specific RXR agonists
A method of treating cancer is disclosed comprising administering to a patient in need of such treatment a RXR agonist at a level below the RAR activating threshold and at or above the RXR...
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8101660 |
Use of 2,5-dihydroxybenzene compounds and derivatives for the treatment of skin cancer
The present invention relates to the use of a 2,5-dihydroxybenzene derivative of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the treatment and/or...
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8101628 |
Imidazolidinonyl aminopyrimidine compounds for the treatment of cancer
The present invention provides novel imidazolidinonyl aminopyrimidine compounds believed to have clinical use for treatment of cancer through inhibiting Plk1. wherein: R1 hydrogen, hydroxy, halo,...
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8101372 |
Diagnosis and therapy of cancer using SGP28-related molecules
The present invention relates to methods and compositions for the diagnosis and therapy of prostate cancer which utilize isolated polynucleotides corresponding to the human SGP28 gene, proteins...
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8101371 |
Methods for the diagnosis of genitourinary cancer
Methods for the diagnosis of genitourinary (GU) cancer are provided. In particular, urine has been found to contain significant levels of thromboxane receptor β (TPβ) methods for diagnosing GU c...
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8101359 |
Method for determining risk of relapse of breast cancer following tamoxifen adjuvant therapy
The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for...
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8101352 |
Detection of ESR1 amplification in breast cancer
The present invention relates to an in-vitro method of identifying a tumor resulting from a proliferative breast disease as responsive to anti-estrogen treatment. Further, the invention relates to...
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8101342 |
DNA vaccine for treating or preventing cervical cancer comprising a gene encoding HPV protein
Disclosed herein is a DNA vaccine for treating cervical cancer including an E5 gene of human papillomavirus (HPV). Also, disclosed is a combination DNA vaccine for preventing and treating cervical...
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8101195 |
Artificial lymph node for treating cancer
Provided is an artificial lymph node that is persistently effective in cancer treatment in vivo. A method of producing an artificial lymph node capable of inducing cancer antigen-specific immune...
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8101173 |
Method for treating urinary bladder cancer
The present invention discloses an immunotherapeutic method for treating a patient suffering from urinary bladder cancer by administering expanded tumour-reactive CD4+ helper and/or CD8+...
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8101159 |
In vivo methods of identifying compounds which target suppressed cancer cells
In vitro and in vivo methods for identifying compounds capable of targeting suppressed cancer cells such as micrometastatic cells. The in vitro method includes the steps of comparing the response...
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8100839 |
Acoustic monitoring of a breast and sound databases for improved detection of breast cancer
Provided are methods and devices that pertain to the acquisition of data related to breast vascularity associated with breast cancer, use of data, or both, that are associated with the generation...
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8097648 |
Methods and compositions for use in treating cancer
The invention provides methods and compositions for use in treating diseases associated with excessive cellular proliferation, such as cancer.
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8097595 |
Modulation of telomere length in telomerase positive cells and cancer therapy
Induction of telomere shortening, G2 arrest and apoptosis in telomerase positive cancer cells using acyclic nucleoside analogs has been disclosed. In addition, methods for impairment or prevention...
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8097591 |
Polysialic acid derivatives, methods of production, and uses in enhancing cancer antigen production and targeting
The present invention relates to compositions and methods of their production and use, including use in increasing de-N-acetyl sialic acid antigen of a mammalian cell and methods that exploit the...
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8097454 |
Model system for identifying anti-cancer agents
A model system for screening and identification of compounds that interfere with Gli2 dependent tumorigenesis and provide potential use as anticancer agents is provided. In particular, the...
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8097423 |
MN/CA IX and breast cancer therapy
Herein disclosed are methods that are predictive of resistance to endocrine therapy in an estrogen receptor-positive (ER-positive) breast cancer patient. An exemplary method comprises detecting the...
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8097417 |
Methods for detecting therapeutic effects of anti-cancer drugs by monitoring changes in gut flora
Non-invasive methods for monitoring the effect of an agent for treating colorectal cancer, comprising (1) collecting fecal samples from healthy subjects, subjects having precancerous lesions, and...
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8097256 |
Cancer vaccines and vaccination methods
Methods and compositions for treating cancers (e.g., neural cancers) by dendritic cell vaccination are provided herein.
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8097244 |
Human prostate cell lines in cancer treatment
Combinations of cell lines are provided for allogeneic immunotherapy agents in the treatment of cancer. Cancer vaccines generally have been limited to the use of cells that contain at least some...
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8097242 |
Target CA125 peptides for cancer immunotherapy
TADG-12 and CA125 are two proteins expressed with high specificity in ovarian cancer tumors. They thus would be potential antigens for immunotherapy in ovarian cancer. The invention is based on the...
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8097237 |
Non-invasive diagnostic agents of cancer and methods of diagnosing cancer, especially leukemia and lymphoma
The present invention is directed to novel non-invasive diagnostic tools to image cancers, especially, leukemia and non-Hodgkin's lymphomas (NHL) with minimal toxicity in vivo. The present...
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8097236 |
Devices and methods for the treatment of cancer
The invention relates to the treatment of cancer. In particular the invention relates to an internal therapeutic product comprising: (i) an anti-cancer component selected from one or both of: a...
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8095204 |
Apparatus and method for diagnosing breast cancer including examination table
A microwave breast cancer imaging method that includes an examination table that is both comfortable and reliable is provided that includes a support system and an orientation system such that...
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8093564 |
Ion beam focusing lens method and apparatus used in conjunction with a charged particle cancer therapy system
The invention comprises an ion beam focusing method and apparatus used as part of an ion beam injection system, which is used in conjunction with multi-axis charged particle or proton beam...
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8093393 |
Cationic ceramides, and analogs thereof, and their use for preventing or treating cancer
The present invention relates to cationic ceramides, their dihydro-analogs and aromatic analogs and their derivatives, comprising a pyridinium group. Also provided are methods for making cationic...
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8093246 |
O-linked pyrimidin-4-amine-based compounds, compositions comprising them, and methods of their use to treat cancer
O-linked pyrimidin-4-amine-based compounds, pharmaceutical compositions comprising them, and methods of their use are described. Particular compounds of the invention are of formula I:
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8093216 |
Method of treating cancer by inhibition of p95HER-2 production
There is disclosed an initial identification of an N-terminally truncated HER-2/neu product. This product is a 95 kDa polypeptide having in vitro kinase activity (as determined by western...
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8093208 |
Therapeutic peptides for the treatment of metastatic cancer
Interaction between MUC1 and β-catenin can be interrupted using polypeptides or antibodies that specifically bind to the binding site on MUC1. Interruption provides the beneficial effect of ...
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8093013 |
Claudins as markers for early detection, diagnosis, prognosis and as targets of therapy for breast and metastatic brain or bone cancer
Methods of diagnosis, prognosis, and treatment of breast cancer, and of metastatic brain cancer, are provided The diagnostic and prognostic methods involve the immunohistochemical detection of the...
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8093011 |
Biological markers predictive of anti-cancer response to epidermal growth factor receptor kinase inhibitors
The present invention provides diagnostic and prognostic methods for predicting the effectiveness of treatment of a cancer patient with an EGFR kinase inhibitor. Methods are provided for predicting...
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