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9816996 Antibody for detecting epithelial ovarian cancer marker and method for diagnosing epithelial ovarian cancer  
The present invention provides an antibody capable of specifically recognizing and detecting the highly specific cancer marker with respect to the epithelial ovarian cancer, or a fragment of the...
9816995 Biomarker for ovarian cancer CTAP3-related proteins  
The present invention provides a protein-based biomarker that is useful in qualifying ovarian cancer status in a patient. In particular, the biomarker of this invention is useful to classify a...
9816139 Mean DNA copy number of chromosomal regions is of prognostic significance in cancer  
Methods for predicting a disease free time interval (DFI) for a cancer patient under consideration for initial or further chemotherapy treatment are disclosed. The methods include obtaining a...
9816083 Genetically engineered bacterium for treatment of breast cancer, method for constructing the bacterium, and applications thereof  
The current invention discloses a genetically engineered bacterium used for the treatment of breast cancer. The said bacterium is attenuated Salmonella typhimurium VNP20009 with cloned...
9815906 Method of inhibiting or treating cancer metastasis  
The present invention relates to the diagnosis and treatment of cancer, and specifically to a method of diagnosing the presence, status or metastasis of cancer by detecting plasma Hsp90α having...
9815901 Treatment of cancer using a CD123 chimeric antigen receptor  
The invention provides compositions and methods for treating diseases associated with expression of CD123. The invention also relates to chimeric antigen receptor (CAR) specific to CD123, vectors...
9815845 Inhibitors of late SV40 factor (LSF) as cancer chemotherapeutics  
The present invention is directed to methods, compositions and kits for treatment of cancer, e.g. heptacellular carcinoma. In some embodiments, the present invention discloses the use of a...
9814767 Methods and materials for generating CD8+ T cells having the ability to recognize cancer cells expressing a HER2/neu polypeptide  
This document provides methods and materials for generating CD8+ T cells having the ability to recognize cancer cells expressing a HER2/neu polypeptide. For example, methods and materials for...
9814759 Pharmaceutical composition comprising recombinant hemoglobin protein or subunit-based therapeutic agent for cancer targeting treatment  
The present invention provides a pharmaceutical composition containing recombinant hemoglobin protein or tetramer or dimer or subunit for tissue oxygenation and treating cancer. The recombinant...
9814707 Cancer stem cell proliferation inhibitor and intracellular active oxygen accumulation inducer  
The present invention is directed to provide cancer stem cell proliferation inhibitors and inducers of intracellular accumulation of reactive oxygen species. To this end, provided are cancer stem...
9814703 Methods for treating cancer by activation of BMP signaling  
Methods for treating cancer by activation of the Bmp pathway are disclosed. In particular, the invention relates to methods of treating cancer using agents that activate BMP signaling, e.g., FK506...
9814694 Lipidic furan, pyrrole, and thiophene compounds for treatment of cancer, neurological disorders, and fibrotic disorders  
Compounds, methods, and compositions are provided for the treatment of cancer, neurological disorders, and fibrotic disorders. Specifically, the invention includes administering an effective...
9814449 Motorized optical imaging of prostate cancer  
A system, method, and storage device storing computer executable instructions for use in tissue analysis and therapy. A motorized optical probe for illuminating tissue generates light fluorescence...
9814448 Three-dimensional optical imaging and therapy of prostate cancer  
A system, method, and storage device storing computer executable instructions for use in tissue analysis and therapy. An optical probe array has at least two or more optical probes for...
9810691 Biomarker for detecting cancer  
Methods for detecting colorectal cancer in a subject by detection of a galactose-containing 40 kDa molecule in a serum sample from the subject. Methods for quantifying the amount of a...
9809859 Biomarkers for subtypes of cervical cancer  
The present invention relates to biomarkers for chemoradioresistant subtypes of cervical cancer. In particular the present invention relates to a method for predicting a predisposition to a...
9809858 O-glycan pathway ovarian cancer signature  
Biomarkers, methods, assays, and kits are provided for determining the prognosis of and treating a patient with ovarian cancer. Also disclosed are biomarkers, methods, assays, and kits for...
9809857 Methods and signatures for oropharyngeal cancer prognosis  
Methods for determining the prognosis of a subject with oropharyngeal squamous cell carcinoma are described, as well as miRNAs and panels of prognostic miRNAs that are used in the methods.
9809815 Methods and compositions for diagnosis and treatment of cancer  
The present invention relates to the identification of nucleic acid and amino acid sequences that are characteristic of tumor tissues such as ovarian tumor and lung tumor tissues and which...
9809810 Galvanotaxis assay for quantitative assessment of the metastatic potential of cancer cells  
An apparatus and method for accelerating and/or inhibiting the migration of cells by applying a time-varying magnetic field to induce eddy currents that promote electrotaxis (galvanotaxis) of...
9809651 Method of treating cancer with an EGFR targeted immunomodulatory fusion protein  
The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, to nucleotide sequences encoding the fusion proteins,...
9809631 Targeting of podoplanin with lectin for use in the prevention and treatment of cancer  
Lectin compositions and methods for reducing tumor cell growth and preventing or treating cancer are provided.
9809616 Pyrimidine nucleosides and their monophosphate prodrugs for the treatment of viral infections and cancer  
The compounds are of the class of N4-hydroxycytidine nucleosides, modified monophosphate and phosphonates prodrugs analogs, and pharmaceutically acceptable, salts, prodrugs, and other derivatives...
9809615 Anti-cancer compounds from invasive salvinias and methods of treating cancer  
Compositions and methods related to anti-cancer terpenoid compounds isolated from plants in the Salviniaceae family, pharmaceutical compositions comprising the same, and methods of treating cancer.
9809562 NAT10 modulators for treating or preventing laminopathies, aging and cancer  
The invention relates to compounds in the treatment or prevention of disorders associated with Lamin A and/or Lamin C depletion or LMNA mutations, such as laminopathy, premature ageing disorders,...
9809549 Malate salt of N-(4-{[6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-N′(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, and crystalline forms therof for the treatment of cancer  
Disclosed are malate salts of N-(4-{[6,7-bis(methyloxy)-quinolin-4-yl]oxy}phenyl)-N′-(4-fl uorophenyl)cyclopropane-1,1-dicarboxamide, including a (L)-malate salt, a (D)-malate salt, a (DL) malate...
9808543 Iron garnet nanoparticles for cancer radiotherapy and chemotherapy  
Iron garnet nanoparticles and or iron garnet particles containing various activatable nuclides, such as holmium-165 (165Ho) and dysprosium-164 (164Dy), are disclosed in this application. The iron...
9808526 Pharmaceutical kit and methods for cancer treatment via intracavity delivery and for preparing metal nanoparticle-antibody fragment conjugate  
The present invention provides a pharmaceutical kit, methods for cancer treatment and for preparing a metal nanoparticle-antibody fragment conjugate, which can reduce the recurrence rate of cancer...
9808524 Combination of local and systemic immunomodulative therapies for melanoma and liver cancer  
A method for the treatment of cancer comprising administration of a therapeutically effective amount of an intralesional chemoablative pharmaceutical composition, or variant of said composition,...
9808516 Immunogenic fusion proteins for the treatment of cancer  
Provided herein are compositions and methods for eliciting an immune response in a subject. In particular, the present disclosure is directed to immunogenic fusion proteins and methods of...
9808513 Method of treatment of cancer using guanosine 3′, 5′ cyclic monophosphate (cyclic GMP)  
A method of treating cancer through use of guanosine 3′,5′-cyclic monophosphate (cyclic GMP). Cyclic GMP decreases the number of human breast cancer and prostate adenocarcinoma as well as...
9808506 Compositions comprising semaphorins for the treatment of cancer and methods of selection thereof  
A method of selecting a semaphorin for treating cancer in a subject is disclosed. The method comprises determining an expression of a semaphorin receptor on tumor cells of a tumor sample of the...
9808504 Immunogenic epitopes as targets for universal cancer vaccines  
The present invention provides a peptide having an amino acid sequence as set forth in SEQ ID NOs: 1 through 95 and any combination thereof. The peptide or combination of peptides possess OCT4...
9808477 Use of nobiletin in cancer treatment  
The present invention discloses a pharmaceutical composition of treating multidrug resistance cancer, comprising a citrus methoxyflavone and a chemotherapeutic drug, in which the citrus...
9808469 Antitumor activity of multi-kinase inhibitors in triple negative breast cancer  
A composition comprising a) a compound of Formula (I), where R1, R2, and R3 are, each one and independently, hydrogen or a protector group, wherein said protector group may consist of an alkyl...
9808448 Pharmaceutical compounds and use of same in cancer and tauopathies  
Disclosed are compounds of formula (l)-(V): where the substituents are as provided herein. Further disclosed are methods of inhibiting tau aggregation, treating or ameliorating a tauopathy or...
9808440 Pharmaceutical combination comprising metformin and dihydroquercetin and its use for the treatment of cancer  
Provided is a novel medicament capable of reducing the side effects of metformin or a pharmaceutically acceptable salt thereof and useful as an anti-malignant tumor agent, in which metformin or a...
9808439 Use of tangeretin in cancer treatment  
The present invention discloses a pharmaceutical composition of treating multidrug resistance cancer, comprising a citrus methoxyflavone and a chemotherapeutic drug, in which the citrus...
9808434 Compound for treating cancer and diabetes  
One aspect of the disclosure relates to the use of derivatives of dichlorophenyl urea for treating cancers.
9808425 Targeted liposomes in cancer therapy  
The invention provides pharmaceutical compositions containing a vehicle for the targeted delivery of therapeutic and diagnostic agents for the treatment of hyperproliferative diseases. The...
9808217 Breast cancer detection system, breast cancer detection method, breast cancer detection program, and computer-readable recording medium having breast cancer detection program recorded thereon  
A model calculating device calculates a mammary gland normal architecture model that scatters in a fan shape from the nipple toward the greater pectoral muscle with respect to the X-ray image of...
9804166 Methods for single chain variable region ENOX2 antibodies for cancer detection and diagnosis  
Cancers of different cellular or tissue origins express different ENOX2 cancer isoforms or combinations of isoforms and shed these proteins into the circulation. Herein are disclosed methods both...
9804165 Methods and compositions for targeted two-dimensional western blot analysis for early cancer detection and cancer diagnosis up to ten years in advance of clinical symptoms of malignant disease  
The present invention includes methods for detecting benign to malignant transformation of a cancer in a subject, comprising the steps of: collecting a sample from the subject prior to...
9804163 Biomarkers for prostate cancer and methods for their detection  
The invention provides a method for predicting the clinical response to a cancer vaccine in a patient having cancer, a method for determining the immune response to a cancer vaccine in a patient...
9803246 Receptor gene for peptide cancer antigen-specific T cell  
The invention provides the nucleotide sequence and amino acid sequence of the CDR3 domain of the T cell receptor (TCR) gene of a WT1-specific cytotoxic T cell (CTL) against WT1 protein. Also...
9803245 Signature for predicting clinical outcome in human HER2+ breast cancer  
A method of predicting outcome in a subject with for example Her2+ (ERα−) breast cancer comprising: (a) determining a HTICs expression signature comprising determining an expression level of 2 or...
9803185 Method for cancer targeting treatment and detection of arginine using albumin-binding arginine deiminase fusion protein  
The present invention provides a pharmaceutical composition containing albumin-binding arginine deiminase (AAD) fusion protein for treating cancer or other arginine-dependent diseases. The AAD...
9803017 Soluble MIC neutralizing monoclonal antibody for treating cancer  
Disclosed are compositions and methods relating to antibodies that bind soluble Major Histocompatibility Complex class I chain-related (sMIC). Specifically, disclosed are antibodies designed or...
9803014 JAM-C antibodies and methods for treatment of cancer  
A novel method to reduce B-cell lymphoma cell migration to and engraftment of the spleen in patients with JAM-C positive B-cell lymphomas is described. In certain aspects, a method for identifying...
9802998 Short peptide-based therapeutic agent and medicinal composition including the same for inhibiting activities of cancer cells  
The present invention relates to a short peptide-based therapeutic agent and a medicinal composition including the same for inhibiting activities of cancer cells, which includes at least one short...