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D864395 Cover for cancer cell observation camera  
10452970 Methods and systems of evaluating a risk of a gastrointestinal cancer  
A method of evaluating gastrointestinal cancer risk. The method comprises generating a set of features comprising a plurality of current blood test results from a blood collected from a target...
10451626 Method for detecting a solid tumor cancer  
A method for indicating a presence or non-presence of a predefined solid tumor cancer in an individual, comprising the steps of: A. Providing at least one biological sample originating from said...
10451625 Methods of detecting cancer  
Method and kits for detecting cancer, and in particular breast cancer, in a subject by measuring the levels of at least one of a series of biomarkers, as compared to a control sample lacking...
10450357 Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC, SCLC and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10450289 Substituted β-lapachones for treating cancer  
Provided herein are compounds having the general formula compositions, and methods useful for treating cancer and neurodegeneration. The compounds comprise a mitochondria-targeting moiety linked...
10450281 Compounds and methods for treating cancer  
Provided are small molecule inhibitors of ubiquitin specific protease 2, 8 and 12 (USP2 and USP8 and USP12) activity and methods for their use in treating cancers. The small molecule inhibitors of...
10450278 Substituted 2-thioxo-imidazolidin-4-ones and spiro analogues thereof, active anticancer ingredient, pharmaceutical composition, medicinal preparation, method for treating prostate cancer  
Novel (R)-stereoisomers of substituted 2-thioxo-imidazolidin-4-ones of formula 1, or spiro analogues thereof, which exhibit androgen receptor antagonist properties. Also provided are variants of a...
10450275 Compounds and methods for treating cancer, neurological disorders, ethanol withdrawal, anxiety, depression, and neuropathic pain  
Provided herein, inter alia, are compounds and methods of treating diseases including cancer, neurological disease, alcohol withdrawal, depression and anxiety, and neuropathic pain.
10449239 Peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10449238 Peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10449202 Rationale-based design of a targeted therapy for cancer  
The methods, compositions, and kits of the invention are related to the discovery that lestaurtinib reduces levels and pathway activity of an SPOP substrate. Accordingly, described herein are...
10449200 Combined inhibition of the vitamin D receptor and poly(ADP) ribose polymerase (PARP) in the treatment of cancer  
Methods for treating tumors comprise contacting tumor cells expressing the vitamin D receptor with a vitamin D receptor ligand that inhibits homologous recombination in the tumor cells, and...
10449197 Systems and methods for treating cancer  
Embodiments of the invention provide a method of treating cancer, the method comprising providing a subject having cancer cells, and contacting the cancer cells with a therapeutically effective...
10449191 Treatment of prostate cancer  
Methods for treating prostate cancer, including advanced prostate cancer, in a subject in need thereof, include administering once-daily to the subject, at least 80 mg of...
10449186 Phenylethynyl-substituted benzenes and heterocycles for the treatment of cancer  
Halogenated phenylethynyl-substituted heterocycles that possess either an N-alkylamino or N,N-dialkylamino group attached to the heterocycle or halogenated phenylethynyl-substituted benzenes that...
10449178 Glucocorticoid receptor modulators to treat pancreatic cancer  
Methods and compositions for treating a subject hosting a non-ACTH-secreting pancreatic tumor are disclosed. The methods include administering to the subject a chemotherapeutic agent and a...
10449144 WT1 peptide cancer vaccine composition for transdermal administration  
The present invention provides a cancer vaccine composition for transdermal administration for inducing cellular immunity, comprising (i) a WT1 peptide and/or a modified WT1 peptide; and (ii) a...
10448989 High-frequency electroporation for cancer therapy  
The present invention relates to the field of biomedical engineering and medical treatment of diseases and disorders. Methods, devices, and systems for in vivo treatment of cell proliferative...
10448637 Inhibitors of GRB2-associated binding protein 1 (GAB1) and methods of treating cancer using the same  
Identification and evaluation of a set of first-in-class potent inhibitors targeting a new cancer target, Grb2-associated binder˜1 (GAB1), which integrates signals from different signaling...
10445619 Automatic glandular and tubule detection in histological grading of breast cancer  
Methods, systems, and apparatuses for automatically identifying glandular regions and tubule regions in a breast tissue sample are provided. An image of breast tissue is analyzed to detect nuclei...
10444238 Detection of ovarian cancer using antibody arrays  
Disclosed are antibody arrays for the detection of cancer in a human or animal subject, comprising a solid support having disposed thereon in a predetermined spatial configuration, a panel of...
10444237 Anti-pancreatic cancer monoclonal antibody and use thereof  
A hybridoma cell line NM002-1 secreting an anti-human pancreatic cancer monoclonal antibody and deposited under CCTCC Accession NO: C201173. Also, an anti-human pancreatic cancer monoclonal...
10444235 Systems and methods for treating, diagnosing and predicting the response to therapy of breast cancer  
This present invention systems and methods of accessing/monitoring the responsiveness of a breast cancer to a therapeutic compound.
10443105 Methods and compositions for correlating genetic markers with prostate cancer risk  
The present invention provides methods of assessing an individual subject's risk of developing prostate cancer, comprising: a) analyzing a nucleic acid sample obtained from the subject and...
10443104 Breast cancer susceptibility gene GT198 and uses thereof  
It has been discovered that the human GT198 gene (gene symbol PSMC3IP) at chromosome 17q21 acts as a tumor suppressor. The mutation of the GT198 gene causes the increased dominant negative splice...
10443102 Recurrent SPOP mutations in prostate cancer  
The invention relates generally to new prostate cancer markers, and particularly to a class of cancer marked by the presence of missense mutations in SPOP, an E3 ubiquitin ligase component. The...
10443055 Compounds that target MYC microRNA responsive elements for the treatment of MYC-associated cancer  
Novel mIR-330 agents and their methods of use are provided. Methods of treating MYC-associated cancers are provided.
10442867 Compositions and methods for treating cancer with anti-CD19/CD20 immunotherapy  
Chimeric antigen receptors containing CD19/CD20 or CD20/CD19 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and...
10442862 Use of EGFR biomarkers for the treatment of gastric cancer with anti-EGFR agents  
The present invention relates to methods for treating gastric neoplasias, in particular treating patients who have been previously determined to have an EGFR biomarker. Gastric carcinoma (GC) is...
10441813 Method and system for cancer treatment with radiation  
Embodiments generally relate to cancer treatment with radiation sources. The present technology discloses techniques that can enable an automatic generation of radiotherapy trajectories using...
10441810 X-ray psoralen activated cancer therapy (X-PACT)  
A system for treating a diseased site in a human or animal body. The system includes a pharmaceutical carrier including one or more phosphors which are capable of emitting light into the diseased...
10441663 Methods for treating cancer  
The present invention relates to a method of treating cancer in a subject.
10441654 SMC combination therapy for the treatment of cancer  
The present invention includes methods and compositions for enhancing the efficacy of SMCs in the treatment of cancer. In particular, the present invention includes methods and compositions for...
10441645 MSLN targeting DNA vaccine for cancer immunotherapy  
The present invention relates to an attenuated mutant strain of Salmonella comprising a recombinant DNA molecule encoding Mesothelin. In particular, the present invention relates to the use of...
10441643 Methods and materials for treating cancer  
This document provides methods and materials for treating cancer. For example, methods and materials for treating cancer using combinations of antigens are provided. For example, VSV vectors...
10441638 Cyclic acetylcholinesterase c-terminal peptide in the treatment or prevention of cancer or metastasis  
The invention relates to cyclic polypeptides derived from the C-terminus of acetylcholinesterase for use in treating or preventing cancer or metastatic disease.
10441613 Anti-cancer agent comprising HVJ-E and CXCL2  
The present invention provides, as a new anti-cancer agent obtained by combining HVJ-E and a molecule synergistically acting therewith, an anti-cancer agent containing the following (1) and (2):...
10441596 Methods and compositions related to glucocorticoid receptor antagonists and breast cancer  
Embodiments of the invention are directed to methods of determining the prognosis of a breast cancer patient by evaluating the activity of the glucocorticoid receptor in tumor cells. Other...
10441591 Applications for etonogestrel in preparing anti-prostate cancer products  
This invention discloses uses for etonogestrel in preparing anti-prostate cancer products. This invention provides uses for etonogestrel in preparing anti-prostate cancer products. From carrying...
10441587 Treatment of lung cancer with inhibitors of glutaminase  
The invention relates to methods of treating lung cancer using glutaminase inhibitors. In particular, results demonstrate that lung cancers characterized by an EGFR or KRAS mutation are treated by...
10441577 Medicament for treatment of liver cancer  
The invention provides a pharmaceutical composition comprising Sorafenib in combination with an inhibitor of a specific kinase inhibitor as a medicament for the treatment or prevention of liver...
10441564 Fructose analogs and their combinations as anti-cancer agents  
The present invention provides a fructose analogue and a composition thereof which can be used for cancer treatment, has a targeting effect and has little effect on normal cells, particularly when...
10441561 Method for treating benign prostatic hyperplasia (BPH), prostatitis, and prostate cancer  
A method for treating benign prostatic hyperplasia (BPH), prostatitis, and/or prostate cancer, including the step of administering an isothiocyanate functional surfactant to a patient affected by...
10441225 Predicting disease recurrence following trimodality therapy in non-small cell lung cancer using computed tomography derived radiomic features and clinico-pathologic features  
Embodiments include operations, apparatus, methods and other embodiments that access a baseline CT image of a region of tissue (ROT) demonstrating non-small cell lung cancer (NSCLC), segment a...
10441215 Predicting immunotherapy response in non-small cell lung cancer with serial quantitative vessel tortuosity  
One embodiment includes an image acquisition circuit that accesses a pre-treatment and a post-treatment image of a region of tissue demonstrating non-small cell lung cancer (NSCLC), a segmentation...
10438096 Identifying and excluding blurred areas of images of stained tissue to improve cancer scoring  
A method for identifying blurred areas in digital images of stained tissue involves artificially blurring a learning tile and then training a pixel classifier to correctly classify each pixel as...
10436788 Isolation, detection, diagnosis and/or characterization of circulating Trop-2-positive cancer cells  
Described herein are compositions and methods of use of anti-Trop-2 antibodies or antigen-binding fragment thereof to isolate, enrich, detect, diagnose and/or characterize circulating tumor cells...
10436787 Olfactomedin-4, neudesin and desmoplakin as biomarkers of breast cancer  
The present invention is in the technical field of breast cancer management, and more particularly relates to the diagnosis of breast cancer. The invention is more particularly based on the...
10435758 EML4-ALK translocations in lung cancer  
The present disclosure relates to methods for the diagnosis and evaluation of neoplastic disorders, particularly non-small cell lung cancer. Assays are described in which patient test samples are...