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10151760 Method for validating existence of urinary exosome, non-invasive method for identifying urothelial cancer, and method for predicting recurrence and progression of urothelial cancer patient after treatment  
The present disclosure relates to a method for validating an existence of a urinary exosome including steps as follows. A urine sample is obtained from a subject. The urine sample is performing a...
10151756 Predictive markers for polyamine inhibitor cancer therapies  
The present disclosure relates to therapeutic methods and medical uses comprising the identification and use of cancer marker surrogates for increased polyamine expression. These markers may be...
10151755 Method for biomarker and drug-target discovery for prostate cancer diagnosis and treatment as well as biomarker assays determined therewith  
The invention relates to biomarker assays based on protein/peptide biomarkers which show a pronounced differential behaviour between healthy and cancerous sample proteomes e.g. by mass...
10151754 Cell surface prostate cancer antigen for diagnosis  
The present invention provides compositions and methods of detecting prostate cancer in the body fluids or tissues of patients. Prostate cancer is detected by measuring the level of glypican-1 in...
10150815 Method of treating cancer with humanized anti-OX40 antibodies  
The disclosure provides humanized anti-OX40 antibodies. Also provided are methods of making such antibodies, and methods of use, e.g., treatment of cancer.
10150811 Methods for treating vascular leak syndrome and cancer  
Disclosed are methods for treating Vascular Leak Syndrome and preventing cancer metastasis. Further disclosed are methods for treating vascular leakage due to inflammatory diseases, sepsis, cancer...
10150804 Compositions and methods for imaging cancer  
Somatostatin derivative compounds of general formula (I) that may be readily labelled with the isotope fluorine-18 and that have affinity and selectivity for cellular somatostatin receptors are...
10150783 Heterocyclic ITK inhibitors for treating inflammation and cancer  
Disclosed herein are heterocyclic compounds and compositions useful in the treatment of ITK mediated diseases, such as inflammation, having the structure of Formula (I): wherein R1, R2, and X are...
10149889 Compositions for the treatment of cancer, and methods for testing and using the same  
The invention relates to pharmaceutical compositions comprising leukotoxin, including methods to treat lymphoma, and methods to diagnose lymphoma. The lymphoma includes lymphoma cells expressing...
10149887 Peptides and peptidomimetics in combination with t cell activating and/or checkpoint inhibiting agents for cancer treatment  
This invention provides compounds including peptides and peptidomimetics that can be used to treat cell proliferative disorders, such as those associated with benign and malignant tumor cells, and...
10149862 Method of making nanocomposites of metal oxide and reduced graphene oxide and use for cancer treatment  
A facile approach is described to prepare monodisperse Fe3O4 and Co3O4 nanoparticles on chemically reduced graphene oxide (rGO) to form nanocomposites by low temperature solution route and MWI...
10149848 Method for the treatment of bladder cancer  
Methods of treating bladder cancer using terconazole are disclosed herein. Terconazole can be administered as part of a comprehensive treatment program, which can also include chemotherapy,...
10145851 Discovery and validation of cancer biomarkers using a protein analysis methodology to analyze specimens  
Methods are provided for the analysis, including the serial analysis, of very small samples of tissue. The methods utilize a nanofluidic proteomic immunoassay (NIA) to quantify total and...
10144973 Method for determining whether or not aqueous solution contains cancer cells by using improved telomerase assay  
The present invention provides a method for determining whether or not an aqueous solution contains two or more cancer cells. The present method is characterized by the following three matters....
10144771 Lung cancer diagnosis marker, antibody and application thereof  
A human lung cancer marker N3G4, and use of the same as human lung cancer marker is disclosed. Hybridoma cells which produce anti-N3G4 monoclonal antibodies, and the secreted monoclonal antibody...
10144761 Chiral specific boron-containing compounds and their use in treating cancer or amyloidosis  
Useful chiral specific boron-containing compounds, such as boronate, boronate esters, boranamines, borane diamines, boranamine thioesters, and boronic mono/di-thioesters, have been prepared. These...
10144750 Dioxolane analogues of cytidine for the treatment of cancer  
The invention provides compounds of the formula: R1 is OR11, or NR5R5′;R2 is H or F;R5 is H, OH, C1-C6 alkyl, OH, C(═O)R6, O(C═O)R6 or O(C═O)OR6;R5′ is H or C1-C6 alkyl;R6 is C1-C6 alkyl or C3-C7...
10144726 Modulators of the p70S6 kinase for use in the treatment of brain disorders and triple-negative breast cancer  
The invention provides compounds for use in the treatment of a disease or condition selected from brain disorders and triple-negative breast cancer, the compounds being of the formula (1): or a...
10143750 Method for treating cancer  
The present invention relates to a method for the treatment of cancer in a subject which comprises the steps of: (i) administering electroporation to a tumour in the subject; and (ii)...
10143747 Breast cancer therapeutics  
The present invention relates to a method of treating or preventing cancer in a subject comprising administering a therapeutically effective amount of a RANKL inhibitor to said patient.
10143733 Peptides and combination of peptides for use in immunotherapy against breast cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10143732 Peptides and combination of peptides for use in immunotherapy against breast cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10143708 Extracellular matrix compositions for the treatment of cancer  
The present invention is directed to methods of inhibiting cancer cell growth or proliferation by contacting the cancer cell with an extracellular matrix (ECM) composition. Also provided are...
10143704 Methods for treating cancer  
The present invention relates to DOT1L inhibitors. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating disorders in which...
10143677 Taxane analogs for the treatment of brain cancer  
Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or...
10143669 Use of short chain fatty acids in cancer prevention  
The invention relates to compositions for preventing or delaying the onset of hepatocellular cancer. The compositions of the invention may comprise short chain fatty acids. The compositions of the...
10143657 Solid oral dosage form of irinotecan for the treatment of cancer  
The present invention relates to a composition, in particular a solid pharmaceutical composition comprising a compound having the formula I, as a free base or a salt thereof, and a mixture...
10143419 Systems and methods for treating cancer and/or augmenting organ function  
Systems, methods and devices for controlled sympathectomy procedures for neuromodulation in the treatment of subjects having neoplastic conditions are disclosed. Systems, methods, and devices for...
RE47141 Methods of treating fibrosis, cancer and vascular injuries  
This invention relates to use of inhibitors of the transforming growth factor-β (TGF-β) type I receptor (ALK5) and/or the activin type I receptor (ALK4) in treating, preventing, or reducing...
10141933 Self-repairing digital device with real-time circuit switching inspired by attractor-conversion characteristics of a cancer cell  
An electric device, which includes a first switch-unit providing a first internal circuit signal, a first delay circuit unit outputting a second internal circuit signal which is generated by...
10139413 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Means and methods for diagnosing pancreatic cancer in a subject based on a metabolite panel
 
The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing pancreas cancer in a subject and, preferably for...
10139412 Semaphorin 3A as a diagnostic marker for urothelial cancer  
The present invention is directed to methods and kits useful for diagnosis and/or prognosis of urothelial cancer in a subject. The present invention further relates to methods of assessing...
10139394 Method for controlling cancer metastasis or cancer cell migration by modulating the cellular level of lysyl tRNA synthetase  
The present invention relates to a novel function of lysyl tRNA synthetase, that is, lysyl tRNA synthetase interacts with 67LR through translocation of KRS into plasma membrane, and so enhances...
10139349 Diagnosis of cancer  
A method is provided including obtaining an infrared (IR) spectrum of a blood plasma sample by analyzing the blood plasma sample by infrared spectroscopy, and based on the infrared spectrum,...
10138523 Cancer biomarker and diagnostic  
The application discloses new biomarkers and methods useful in the diagnosis, prognosis and/or monitoring of, or as a therapeutic or research target for, solid tumor cancers, such as colorectal...
10138488 Cancer vaccine for dogs  
The present invention provides an immunogenic composition comprising a nucleic acid that comprises a sequence encoding a dog telomerase deprived of telomerase catalytic activity, or a fragment...
10138481 miRNAs useful for identifying targets associated with cancer  
Several miRNAs are described that are useful in diagnosing and treating prostate cancer, or pancreatic cancer. The miRNAs bind with targets that are associated with prostate cancer or pancreatic...
10138479 Targeting the glutamine to pyruvate pathway for treatment of oncogenic Kras-associated cancer  
Methods and kits for GPP-targeting, e.g., for the treatment of oncogenic Kras-associated cancers, and methods for determining the efficacy of those methods are provided.
10138299 Cancer immunotherapy by disrupting PD-1/PD-L1 signaling  
The disclosure provides a method for immunotherapy of a subject afflicted with cancer, comprises administering to the subject a composition comprising a therapeutically effective amount of an...
10138287 Uterine cancer treatments  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10138216 Highly selective anti-cancer agents targeting non-small cell lung cancer and other forms of cancer  
Described herein are analogues of 2-methyl-3-(2-ethynylthiazol-4-yl)cyclopent-2-enol and the corresponding ketone 3-(2-ethynylthiazol-4-yl)-2-methylcyclopent-2-enone, the analogues having terminal...
10137204 Anti-DLL3 antibody drug conjugates for treating cancer  
Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
10137203 HER2 aptamer-anticancer drug complex for cancer cell chemotherapy  
A method of manufacturing a complex for cancer cell chemotherapy comprises an aptamer preparation step of preparing a nucleic acid aptamer having an aptamer base sequence specifically binding to...
10137195 Therapy involving antibodies against Claudin 18.2 for treatment of cancer  
The present invention generally provides a therapy for effectively treating and/or preventing diseases associated with cells expressing CLDN18.2, in particular cancer diseases such as...
10137182 Cancer vaccines and vaccination methods  
Compositions of multipeptide vaccines comprising at least seven tumor associated antigens, compositions of antigen presenting cell (e.g., dendritic cell) based vaccines presenting epitopes from at...
10137149 Particles for the treatment of cancer in combination with radiotherapy  
The invention provides a particle comprising a metal oxide which is doped with at least one rare earth element, wherein the metal oxide is selected from titanium dioxide, zinc oxide, cerium oxide...
10137125 Benzenesulfonamide derivatives of quinoxaline, pharmaceutical compositions thereof, and their use in methods for treating cancer  
Benzenesulfonamide derivatives of quinoxaline that are kinase inhibitors, pharmaceutical compositions and methods of using these derivatives, e.g., for treatment of cancer are described.
10137121 Methods of treating cancer with farnesyltransferase inhibitors  
The present invention relates to the field of cancer therapy. Specifically, provided are methods of treating cancer, for example, peripheral T-cell lymphoma (“PTCL”), with a farnesyltransferase...
10136944 Systems and methods for treating cancer and/or augmenting organ function  
Systems, methods and devices for controlled sympathectomy procedures for neuromodulation in the treatment of subjects having neoplastic conditions are disclosed. Systems, methods, and devices for...
10134148 Method of assessing breast density for breast cancer risk applications  
Breast density is a significant breast cancer risk factor measured from mammograms. Disclosed is a methodology for converting continuous measurements of breast density and calibrated mammograms...