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10049770 Prediction of recurrence of non-small cell lung cancer  
Methods, apparatus, and other embodiments associated with predicting non-small cell lung cancer (NSCLC) patient response to adjuvant chemotherapy therapy using radiomic features extracted from...
10048266 Diagnostic biomarkers and therapeutic targets for pancreatic cancer  
We identified >40 proteins that elicited at least a 2-fold increase in antibody response post-pancreatic-cancer vaccination, from each of three patients' sera. The antibody responses detected...
10048264 Lung cancer biomarker  
The present invention relates to a lung cancer biomarker for diagnosing early stage lung cancers or predicting prognosis of lung cancers, which comprises a GM2AP protein. The present invention...
10047403 Diagnostic methods for determining prognosis of non-small cell lung cancer  
The present disclosure provides methods for identifying early stage non-small-cell lung cancer (NSCLC) patients who will have an unfavorable prognosis for the recurrence of lung cancer after...
10047402 RASAL1 is a major tumor suppressor gene in thyroid cancer  
The present invention relates to the field of cancer. More specifically, the present invention provides methods and compositions useful for treating thyroid cancer. In certain embodiments, the...
10047401 Expression protein-coding and noncoding genes as prognostic classifiers in early stage lung cancer  
The invention provides novel biomarkers (four genes BRCA1, HIF1A, DLC1, and XPO1 alone or in combination of miR-21) for early stage lung cancer.
10047399 ABCA1 downregulation in prostate cancer  
A method of providing a prognosis or diagnosis of prostate cancer in a subject is described. The method includes obtaining a urine or prostate sample from the subject; determining the level of...
10047398 Method for the diagnosis, prognosis and treatment of breast cancer metastasis  
The present invention relates to a method for the diagnosis or the prognosis of metastasis in breast cancer which comprises determining if the c-MAF gene is amplified in a primary tumor sample....
10047397 Breast cancer associated circulating nucleic acid biomarkers  
The invention provides methods and reagents for diagnosing breast cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
10047164 Methods and compositions for the treatment of pancreatic cancer  
A composition comprising a TLR2 antagonistic antibody or antigen binding fragment thereof for use in the treatment or prophylaxis of pancreatic cancer is provided. The antibody or antigen binding...
10047151 Methods for the treatment of cancer and inflammatory diseases using cereblon as a predictor  
Uses of the protein cereblon as a predictor of clinical sensitivity to cancer, inflammatory diseases, and patient response to drug treatment.
10047131 Peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10047116 Nanoparticles, process for preparation and use thereof as carrier for amphipatic and hydrophobic molecules in fields of medicine including cancer treatment and food related compounds  
The present invention regards nanoparticles comprising a sterol and a component derived from Quillaja saponaria Molina selected from quillaja acid and quillaja saponin, which nanoparticles do not...
10047115 Cyclic dinucleotides useful for the treatment of inter alia cancer  
A compound of formula (I) or a pharmaceutically acceptable salt and tautomers thereof, compositions, combinations and medicaments containing said compounds and processes for their preparation. The...
10046172 Controller and flexible coils for administering therapy, such as for cancer therapy  
Disclosed herein are systems and methods for providing a portable magnetic field therapy system for treatment of diseases and adverse health conditions, such as cancer.
10046067 Decorin gene delivery system and cancer treatment  
The present invention relates to a novel gene delivery system and recombinant adenovirus comprising the decorin-encoding sequence to enhance transduction efficiency of transgenes, a pharmaceutical...
10046002 Method for treating cancer using chemokine antagonists  
What is described is a method for treating cancer in a patient in need of such treatment through the use of an antagonist to CXCR1 and/or CXCR2 receptors by administering a therapeutically...
10045962 Uses of duloxetine HCL medicament in preparing pharmaceutical treatment of cancer  
Provided in the present invention are uses of duloxetine hydrochloride in preparing a pharmaceutical composition for treatment of cancer.
10045731 Device and apparatus to facilitate cervix cancer screening  
An apparatus for detecting cervical cancer comprising, a mechanical structure configured to expose cervical region comprising, a first duck-billed blade forming a hollow cylinder at one end and a...
10045698 Apparatus and method for detecting a presence of cancer  
A diagnostic apparatus (20) for detecting a presence of breast cancer in a patient disposed in a testing position. The diagnostic apparatus (20) includes a housing (44) and a camera assembly (58)...
10042983 Apparatus for cancer diagnosis  
The present invention provides an apparatus for screening cancer, which reads low-mass ion mass spectrum for diagnosing cancer based on biostatistical analysis with respect to low-mass ions...
10042977 Method utilizing repeat PSA screening for diagnosis of virulent prostate cancer  
A method for detecting aggressive prostate cancer is described, for instance for use in determination of the need for biopsy based. Disclosed methods recognize the difference in PSA rate of change...
10041948 Materials and methods for determining cancer risk  
This document relates to materials and methods involved in assessing inflammatory bowel disease patients at risk for developing cancer. For example, materials and methods for monitoring colorectal...
10041938 Measuring a level of a 5-hydroxymethylcytosine in a sample from a subject having a cancer or suspected of having cancer  
Provided herein are methods and kits for measuring a level of a 5-hydroxymethylcytosine in a nucleotide sequence from a subject, wherein the subject is a subject having a cancer or suspected of...
10041933 Modulators of the interaction of astrin and raptor, and uses thereof in cancer therapy  
The present invention relates to modulators of the interaction of astrin and raptor, and their uses in the treatment of mTOR related diseases, such as cancer.
10041129 Immune gene signatures in cancer  
This invention relates to methods for selecting a treatment, treating, and predicting survival time in subjects with cancer, such as colorectal cancer, based on tumor expression levels of...
10041126 Monocyte biomarkers for cancer detection  
The disclosure relates to the field of biomarkers to diagnose a disease, more particularly to the field of biomarkers to diagnose cancer, and most particularly to colorectal cancer. Specifically,...
10041124 Methylation biomarkers for ovarian cancer  
Different combinations of methylation status based biomarkers can be used to test for ovarian cancer with high sensitivity and high specificity.
10041123 Recurrent gene fusions in prostate cancer  
Recurrent gene fusions in prostate cancer of androgen regulated genes or housekeeping genes and ETS family member genes are described. Compositions and methods having utility in prostate cancer...
10040853 Methods and compositions involving NKG2D inhibitors and cancer  
Embodiments methods and compositions involving inhibitors of the immunoreceptor Natural Killer Group 2, Member D, (NKG2D) for inhibiting tumor progression and treating cancer.
10040846 Compositions and methods for generating a persisting population of T cells useful for the treatment of cancer  
The present invention provides compositions and methods for generating a genetically modified T cells comprising a chimeric antigen receptor (CAR) having an antigen binding domain, a transmembrane...
10040789 1,3,4-thiadiazole compounds and their use in treating cancer  
A compound of Formula (I): or a pharmaceutically acceptable salt thereof, is described. Q can be pyridazin-3-yl, 6-fluoropyridazin-3-yl; R1 can be H; R2 and R3 can each independently be C1-C6...
10040788 1,3,4-thiadiazole compounds and their use in treating cancer  
The specification relates to compounds of Formula (I), and pharmaceutically acceptable salts thereof, where Q, R, R1 and R2 have any of the meanings defined herein. The specification also relates...
10039846 Compositions targeting bradykinin receptor B1 for medical imaging of cancer and other disorders  
Bradykinin B1 receptor (B1R) targeting peptides and compounds are radiolabelled with radioisotopes that are suitable for imaging and/or radiotherapy. The radiolabelled peptides and compounds have...
10039796 Mutant herpes simplex virus-2 for cancer therapy  
The present invention is directed to the composition and use of a modified Herpes Simplex Virus Type 2 (HSV-2) as a medicament in the treatment of cancer. The modified HSV-2 has fusogenic...
10039771 Method for cancer cell reprogramming  
In one embodiment, the invention provides a method of inhibiting cAMP efflux and increasing intracellular cAMP in a subject who suffers from, or who is at risk of developing, a cancer by...
10039764 Treatment and diagnosis of cancer and precancerous conditions using PDE10A inhibitors and methods to measure PDE10A expression  
Disclosed are methods for treating cancer and precancerous conditions with PDE10A specific inhibitors and diagnosis of neoplastic diseases based on elevated levels of PDE10A.
10039752 Methazolamide for the treatment of cancer  
The present invention relates to methods of using methazolamide to treat pancreatic cancer. Pancreatic cancer can be treated by administering to a patient in need thereof an effective amount of...
10039731 Treatment of cancer with specific RXR agonists  
A method of treating cancer is disclosed comprising administering to a patient in need of such treatment a RXR agonist at a level below the RAR activating threshold and at or above the RXR...
10039725 Method for treating non-melanoma skin cancer by inducing UDP-glucuronosyltransferase activity using pterostilbene  
A method is provided for treating an individual for a cellular proliferative disorder, including administering to the individual in need of such treatment a therapeutically effective amount of the...
10039716 Liposomal cisplatin compositions for cancer therapy  
The present invention provides a composition for the treatment of cancer including zwitterionic liposomes consisting essentially of: 50-65 mol % of a phosphatidylcholine lipid, 30-45 mol % of...
10036752 Agents and methods for determining colorectal cancer status  
The invention provides a method of determining the colorectal cancer status of subject, comprising applying to a colon and/or rectal surface an agent which is able to distinguish between a) mature...
10035009 Systems and methods for treating pancreatic cancer  
A method of treating pancreatic cancer includes: inserting a device into a stomach or a duodenum; securing at least a portion of the device in position relative to the stomach or the duodenum; and...
10034939 Synergistic combination of immunologic inhibitors for the treatment of cancer  
In some embodiments, the methods involve the use of a combination of at least two of the following: an inhibitor of indoleamine-2,3-dioxygenase (IDO), an inhibitor of the PD-L1/PD-1 pathway, an...
10034926 Use of toll-like receptor agonist for treating cancer  
The present invention is directed to methods and agents used for treating cancer in Toll-Like Receptor 5-expressing tissues by providing a Toll-Like Receptor agonist such as flagellin. The present...
10034903 Bacterium-based microrobot capable of targeting cancer tissue  
To provide a bacterium-based microrobot which can be specifically targeted to cancer in vivo, the present invention provides a drug delivery system for cancer tissue, comprising a bacterium, and a...
10034901 Cancer immunotherapy  
Methods of providing populations of NKT and/or γδ T cells, and their use, e.g., in therapies such as cancer immunotherapy.
10034895 Local application of D-lactic acid dimer is selectively cytotoxic when applied to cancer cells  
At equimolar concentrations, D-lactic acid dimer is more cytotoxic than L-lactic acid when directly applied to human HeLa cells in culture. The cytotoxicity of D-lactic acid dimer is an...
10034860 Estrogen receptor modulator for the treatment of locally advanced or metastatic estrogen receptor positive breast cancer  
Described herein are methods of treating locally advanced or metastatic estrogen receptor positive breast cancer.
10030271 Gene expression profile associated with prostate cancer  
Using an RT-PCR platform, detection of gene transcripts highly expressed in prostate tissue and expressed in peripheral blood mononuclear cells (PBMC) from patients with mCRPC can provide a more...