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10426728 Synergistic liposomal formulation for the treatment of cancer  
The present disclosure relates to the synergistic liposomal formulation comprising, phophatidylcholine, stearylamine and anticancer drugs for the treatment of cancer. The PC:SA cationic liposome...
10424411 Biopsy-free detection and staging of cancer using a virtual staging score  
A method for predicting a cancer staging score from medical image data includes receiving patient data for a plurality of patients, where patient data for each of the plurality of patients...
10422005 Methods for treating colorectal cancer using prognostic genetic markers  
This invention relates to prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for colorectal cancer. Specifically, this invention...
10421968 Amphiphilic dendrimers complexed with siRNA for treatment of cancer  
The invention pertains to amphiphilic dendrimers complexed with Bcl3 siRNA. The amphiphilic dendriplexes described herein are biodegradable and exhibit enhanced siRNA delivery. The amphiphilic...
10421960 RNA engineered T cells for the treatment of cancer  
The present invention relates to compositions and methods for generating RNA Chimeric Antigen Receptor (CAR) transfected T cells. The RNA-engineered T cells can be used in adoptive therapy to...
10421820 Bruton's tyrosine kinase as anti-cancer drug target  
Receptor protein kinases (RPTKs) transmit extracellular signals across the plasma membrane to cytosolic proteins, stimulating formation of complexes that regulate key cellular functions. Over half...
10421797 Short peptide-based therapeutic agent and medicinal composition including the same for inhibiting activities of cancer cells  
The present invention relates to a short peptide-based therapeutic agent and a medicinal composition including the same for inhibiting activities of cancer cells, which includes at least one short...
10420838 Methods for treating cancer using iNOS-inhibitory compositions  
Disclosed are methods for treating one or more mammalian cancers, and in particular, methods for treating human melanoma, or a head or neck cancer, that employ therapeutically-effective amounts of...
10420816 Immunotherapy against several tumors including gastrointestinal and gastric cancer  
A method of treating a patient who has gastric cancer, gastrointestinal cancer, colorectal cancer, pancreatic cancer, lung cancer, and/or renal cancer includes administering to said patient a...
10420814 Composition for treating cancer stem cells  
The present invention relates to a composition for effectively treating cancer stem cells, and more specifically to a composition for treating cancer stem cells, which contains a glucose uptake...
10420808 Seaweed extract and composition useful against cancer cells  
The present invention provides a crude extract and fractions from the seaweeds Chaetomorpha Cannabina (CC) or Cladophora sericea (CS), method of preparation and its use for inhibiting the growth...
10420757 Pancreatic cancer therapy and diagnosis  
The current disclosure relates to methods for treating pancreatic cancer or chronic pancreatitis in a subject comprising administering an antagonist of a dopamine receptor to the subject wherein...
10420754 Use of maleimide derivatives for preventing and treating cancer  
The present invention is related to a compound of formula (I): a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, a metabolite thereof or a prodrug thereof; for use...
10420747 Cancer treatment method using ailanthone compounds  
A pharmaceutical composition comprising an ailanthone (AIL) compound or a derivative thereof, for the treatment of diseases or conditions caused by, dependent from, or associated with excessive...
10420734 Method of treating cancer using selective estrogen receptor modulators  
Disclosed herein are methods of treating subjects suffering from estrogen receptor positive cancer of the brain by administering a selective estrogen receptor degrader (SERM). Also disclosed are...
RE47609 System for detecting bone cancer metastases  
The invention relates to a detection system for automatic detection of bone cancer metastases from a set of isotope bone scan images of a patients skeleton, the system comprising a shape...
10416164 Methods for determining breast cancer risk  
The present disclosure relates generally to determining the risk of developing breast cancer. In particular, the present disclosure provides materials and methods for determining whether a subject...
10416163 Method and treatment of recurring endometrial cancer with an inhibitor of USP14  
USP14 is a biomarker for recurrent disease and inhibition of USP14 is of therapeutic benefit for women with endometrial or ovarian cancer.
10414798 Cancer stem cell targeting peptide and use thereof  
A synthetic peptide that targets cancer stem cells is provided. The peptide consists of the amino acid sequence of anyone of SEQ ID NO: 1 to SEQ ID NO: 15. Also provided is a composition...
10414778 Methods for treatment of resistant cancer  
The present disclosure describes a method to treat conditions, including cancer, using compounds that can target resistant cancer cells. The compounds of the invention can decrease the rate of...
10414771 Compounds useful for inhibiting metastasis from cancer and methods using same  
The present invention includes compositions that are useful in preventing or treating metastasis in a subject diagnosed with cancer. The present invention also includes methods of preventing or...
10414745 Phenol derivatives to treat cancer  
The present invention relates to compounds of general formula (I) wherein R1-R8 take various meanings, pharmaceutical compositions containing them and their use in medicine, particularly for the...
10413612 Method of treating cancer with a biomaterial and a toll-like receptor agonist  
Provided are drug delivery compositions and devices useful for the treatment and/or prevention of cancer and metastatic tumors. For example, a drug delivery device is provided that comprises a...
10413606 Methods for treating cancer with nanoparticle complexes of albumin-bound paclitaxel and anti-VEGF antibodies  
This document provides methods and materials for treating cancer (e.g., skin cancer) with nanoparticle complexes of albumin-bound paclitaxel and anti-VEGF antibodies.
10413558 Multi-ingredient pharmaceutical composition for use in cancer therapy  
A pharmaceutical composition or kit of parts comprising at least three ingredients from a HMG-CoA reductase inhibitor, a leukotriene antagonist, a proton pump inhibitor, melatonin or a melatonin...
10413545 Imidazolin-5-one derivative useful as FASN inhibitors for the treatment of cancer  
The present invention is directed to imidazolin-5-one derivatives, pharmaceutical compositions containing them, and their use as FASN inhibitors, in for example, the treatment of cancer, obesity...
10413540 Glucocorticoid receptor modulators to treat cervical cancer  
Methods for treating a subject having a cancerous tumor are disclosed. The methods comprise administering to the subject an effective amount of a non-steroidal selective glucocorticoid receptor...
10413539 Therapy for metastatic urothelial cancer with the antibody-drug conjugate, sacituzumab govitecan (IMMU-132)  
The present invention relates to therapeutic ADCs comprising SN-38 attached to an anti-Trop-2 antibody or antigen-binding antibody fragment. The ADC may be administered at a dosage of between 4...
10413538 Administration of karenitecin for the treatment of platinum and/or taxane chemotherapy-resistant or -refractory advanced ovarian cancer  
The present invention discloses and claims methods and compositions for the treatment of subjects having advanced ovarian cancer, including platinum and/or taxane chemotherapy resistant or...
10413531 Methods of treating bladder cancer  
The present invention provides methods and compositions for treating bladder cancer, including metastatic bladder cancer and non-muscle-invasive bladder cancer, by administering a composition...
10412939 Rodent model of prostate cancer  
This disclosure provides a rodent model of prostate cancer. The rodents disclosed herein comprise a transgene that provides prostate-specific expression of an oncogenic protein (e.g, an SV40 tumor...
10408839 Biomarker panel for diagnosing cancer  
An in vitro method for the diagnosis, prognosis, stratification and/or monitoring of colorectal cancer in a subject includes detecting the level of AREG, CEA, HGF-receptor, ErbB4-Her4, CD69, PSA,...
10407738 Markers for breast cancer  
Correlations between polymorphisms and breast cancer are provided. Methods of diagnosing, prognosing, and treating breast cancer are provided. Systems and kits for diagnosis, prognosis and...
10407737 Methods and kits for identifying pre-cancerous colorectal polyps and colorectal cancer  
Methods and kits for identifying a subject having pre-cancerous advanced polyps or colorectal cancer based on the expression profile(s) of specific mRNA biomarkers. Methods and kits for...
10407736 Expression of ETS related gene (ERG) and phosphatase and tensin homolog (PTEN) correlates with prostate cancer capsular penetration  
The disclosure provides methods for characterizing a prostate cancer sample by detecting expression of ERG, PTEN or both, changes in which relative to a normal control are shown herein to be...
10407731 Biomarker panels for predicting prostate cancer outcomes  
This document provides methods and materials related to assessing male mammals (e.g., humans) with prostate cancer. For example, methods and materials for predicting (1) which patients, at the...
10407446 Amino-triazolopyridine compounds and their use in treating cancer  
The specification generally relates to compounds of Formula (I): and pharmaceutically acceptable salts thereof, where R1 and R2 have any of the meanings defined herein. The specification also...
10406248 Molecular imaging of cancer cells in vivo  
Cellular targets on cancer cells have been identified that can be used with targeted molecular imaging to detect the cancer cells in vivo. Non-invasive methods for detecting cancer cells, such as...
10406228 Process for making iron oxide nanoparticle preparations for cancer hyperthermia  
Iron oxide nanoparticle compositions, methods of preparing the nanoparticles using high gravity controlled precipitation (HGCP), and methods of using the nanoparticles are disclosed.
10406216 In situ antigen-generating cancer vaccine  
The invention provides compositions and methods for utilizing scaffolds in cancer vaccines.
10406188 Method for inhibiting telomerase in cancer cell using luterion  
The present disclosure relates to a method for inhibiting telomerase in cancer cells by means of luterion and, more particularly, to a method for inhibiting telomerase activity in cancer tissues,...
10406185 Cancer therapy with a parvovirus combined with a BCL-2 inhibitor  
Described is a pharmaceutical composition comprising (a) a parvovirus and (b) an Bcl-2 inhibitor and the use of said composition for treatment of cancer, e.g., a solid tumor. Preferred inhibitors...
10406138 Pharmaceutical combinations for treating cancer  
The present invention is directed to a combination comprising a proteasome inhibitor and a compound of formula I or a pharmaceutically acceptable salt thereof: to a pharmaceutical composition and...
10406128 Treatment and diagnosis of colon cancer  
The present invention discloses novel agents and methods for diagnosis and treatment of colon cancer. Also disclosed are related arrays, kits, and screening methods.
10406125 Combination comprising an aminothiolester compound or a pharmaceutically acceptable salt thereof and a compound able to increase the H2O2 level in cancer cells of a subject  
The present invention relates to a combination comprising an aminothiolester compound or a pharmaceutically acceptable salt thereof, in particular the S-methyl...
10406124 Method of treatment of gynecological cancer with anti-RAGE antibodies  
A therapeutic agent comprising a cell binding agent which binds the Receptor for Advanced Glycation End (RAGE) products linked to an anti-cancer drug, for use in the treatment of gynaecological...
10401365 Inhibition of chemokine CCL7 or receptor CCR3 of same for the treatment and diagnosis of prostate cancer  
The invention concerns an inhibitor of the expression of chemokine CCL7 or an inhibitor of the expression of the receptor CCR3 or an inhibitor of CCL7/CCR3 interaction for the use of same to...
10401364 Drug selection for colorectal cancer therapy using receptor tyrosine kinase profiling  
The present invention provides methods for selecting a suitable anticancer drug therapy, and for identifying and predicting response, for the treatment of colorectal cancer. The present invention...
10401357 Treating cancer  
A method for treating cancer comprising applying peripheral blood from a patient or subject to an apheresis column loaded with a solid support comprising one or more binding reagents capable of...
10400290 Mitochondrial DNA deletion between about residues 12317-16254 for use in the detection of cancer  
The present invention relates to methods for predicting, diagnosing and monitoring cancer. The methods comprise obtaining biological samples, extracting mitochondrial DNA (mtDNA) from the samples,...