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7982015 Compositions and methods for treatment of cancer  
The present invention concerns compositions and methods for the treatment of disorders characterized by the overexpression of an LIV-1. More specifically, the compositions include DNA and amino...
7982004 Nucleic acid and corresponding protein entitled 161P5C5 useful in treatment and detection of cancer  
A novel gene (designated 161P5C5) and its encoded protein, and variants thereof, are described wherein 161P5C5 exhibits tissue specific expression in normal adult tissue, and is aberrantly...
7981939 Application of 2-bromide-isovanillin for the manufacture of a medicament for anti-cancer or/and radiation/chemotherapy sensitization  
Use of 2-bromo-isovanillin in the preparation of an anticancer medicament and/or radio- and chemotherapy sensitizing medicament is disclosed. The medicament for the treatment of cancers and/or for...
7981903 2-[2-{phenylamino}-1H-pyrrolo[2,3-D]pyrimidin-4-yl)amino] benzamide derivatives as IGF-1R inhibitors for the treatment of cancer  
Novel pyrrolopyrimidines as shown in formula (I): and pharmaceutically acceptable derivatives thereof. The compounds are useful in the inhibition of IGF-1R.
7981625 Prostate cancer glycan markers and autoantibody signatures  
Disclosed are methods for probing the immunogenic sugar moieties of prostate cancer cells. The methods detect a number of glyco-epitopes that are highly and differentially expressed among prostate...
7981618 Diagnostic and therapeutic methods and compositions involving PTEN and breast cancer  
Patients with ErbB2-overexpressing cancers can be given an ErbB2 targeting agent as a therapeutic regimen but not all patients are responsive. The present invention concerns the diagnostic,...
7981613 Diagnosis kits and method for detecting cancer using polymorphic minisatellite  
The present invention relates to a kit and a method for diagnosing cancer using polymorphic minisatellites (MS), more specifically, relates to a primer set for detecting polymorphic minisatellites...
7981603 Methods for identifying cancer risk  
The present invention provides methods and kits for identifying an increased risk of developing cancer in a subject. The methods include analyzing a first biological sample, such as a blood sample,...
7977372 Ortho aminoamides for the treatment of cancer  
Compounds of formula are HDAC inhibitors. These compounds are useful for the treatment of diseases such as cancer in humans or animals.
7977369 Medical compositions for intravesical treatment of bladder cancer  
Methods for treating bladder cancer comprising intravesicular administration of a stabilized pharmaceutical formulation comprising...
7977062 Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer  
A novel gene 0161P2F10B (also designated 161P2F10B) and its encoded protein, and variants thereof, are described wherein 161P2F10B exhibits tissue specific expression in normal adult tissue, and is...
7976854 Method of treating skin requiring skin cancer treatment  
A treatment regimen for treating skin subject to skin cancer treatments involves the application of supplemental composition(s) such as preparatory composition(s), protective composition(s), and...
7976852 Compositions and methods for cancer immunotherapy  
The invention relates to immunotherapeutic compounds and to methods for stimulating an immune response in a subject individual at risk for developing cancer, diagnosed with a cancer, in treatment...
7976846 Stress protein compositions and methods for prevention and treatment of cancer and infectious disease  
Pharmaceutical compositions comprising a stress protein complex and related molecules encoding or cells presenting such a complex are provided. The stress protein complex comprises an hsp110 or...
7976842 Treatment of metastatic breast cancer  
The present invention relates to the use of an anti-EpCAM antibody for the manufacture of a medicament for the treatment of metastatic breast cancer. The present invention further relates to a...
7976825 Cancer cell diagnosis by targeting delivery of nanodevices  
Macromolecular contrast agents for magnetic resonance imaging are described. Biomolecules and their modified derivatives form stable complexes with paramagnetic ions thus increasing the molecular...
7973135 Compositions and methods for targeting cancer-specific transcription complexes  
The invention provides molecules that target cancer-specific transcription complexes (CSTC), compositions and kits comprising CSTC-targeting molecules, and methods of using CSTC-targeting molecules...
7973017 Treatment of cancer by inhibition of IGFBP's and clusterin  
Agents that reduce the amount of IGFBP-2 and/or IGFBP-5 and that are known to be useful in the treatment of cancer result in increased expression of the protein clusterin. Since clusterin can...
7972817 Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer  
This invention relates to the use of extracellular ribonucleic acid (RNA) found circulating in the plasma or serum fraction of blood. Specifically, this invention enables the extraction of...
7972774 Methods of diagnosing cervical cancer  
The invention provides reagents and methods for detecting pathogen infections in human samples. This detection utilizes specific proteins to detect the presence of pathogen proteins or abnormal...
7972772 KIF11 and method for diagnosing non-small cell lung cancer  
Disclosed are methods for detecting non-small cell lung cancer (NSCLC) using differentially expressed genes KIF11, GHSR1b, NTSR1, and FOXM1. Also disclosed are methods of identifying compounds for...
7972770 Methods of detection of cancer using peptide profiles  
The disclosed methods address the identification and monitoring of cancer in a subject using serum peptide profiles. Such profiles allow the detection of the differential presence of certain serum...
7972609 Method of treating cancer  
Present invention relates to the method of treating cancer. According to present invention, a pharmaceutical composition made from ‘Mycobacterium w’ (Mw) is found to be useful in the management of ...
7972600 IGF-IR antagonists as adjuvants for treatment of prostate cancer  
The present invention relates to a method of treating prostate cancer with androgen deprivation therapy and an insulin-like growth factor receptor (IGF-IR) antagonist. Although the response rate of...
7968738 Compounds and methods for the treatment of cancer  
The present invention provides organic arsenicals. Many of these compounds have potent in vitro cytotoxic activity against numerous human tumor cell lines, both of solid and hematological origin,...
7968531 Use of 2,5-dihydroxybenzenesulphonic acid in the production of medicaments for the treatment of angiodependent diseases such as cancer and psoriasis  
The invention relates to the use of 2,5-dihydroxybenzenesulfonic acid in the production of medicaments for the treatment of angiodependent diseases. More specifically, the invention relates to the...
7968526 Antisense oligonucleotides directed to ribonucleotide reductase R2 and uses thereof in the treatment of cancer  
The present invention provides antisense oligonucleotides directed to a mammalian ribonucleotide reductase R2 gene and combinations of the antisense oligonucleotides with one or more...
7968514 Pharmaceutical composition for treating or preventing ovarian cancer  
The invention relates to therapeutic and prophylactic treatment of ovarian cancer and metastases thereof. More specifically, the invention relates to immunogenic polypeptides comprising at least a...
7968294 SLIT2 underexpression in metastatic prostate cancer  
This invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, this invention relates to SLIT2 cancer...
7968283 Gene expressed in prostate cancer  
A novel testis-specific gene expressed in human prostate cancer, designated 22P4F11, is described. Analysis of 22P4F11 mRNA expression in normal prostate, prostate tumor xenografts, and a variety...
7968281 Methods of modulating SMYD3 for treatment of cancer  
The present invention features a method for determining the methyltransferase activity of a polypeptide and screening for modulators of methyltransferase activity, more particularly for modulators...
7968115 Liposomal curcumin for treatment of cancer  
The present invention provides a compositions and methods for the treatment of cancer, including pancreatic cancer, breast cancer and melanoma, in a human patient. The methods and compositions of...
7968099 Nucleic acid and corresponding protein entitled 193P1E1B useful in treatment and detection of cancer  
A novel gene (designated 193P1E1B) and its encoded protein, and variants thereof, are described wherein 193P1E1B exhibits tissue specific expression in normal adult tissue, and is aberrantly...
7968090 Nucleic acids and corresponding proteins entitled 191P4D12(b) useful in treatment and detection of cancer  
A novel gene 191P4D12(b) and its encoded protein, and variants thereof, are described wherein 191P4D12(b) exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in...
7964717 RNAi probes targeting cancer-related proteins  
RNAi sequences that are useful as therapeutics in the treatment of cancers of various types, including prostate cancer, sarcomas such as osteosarcoma, renal cell carcinoma, breast cancer, bladder...
7964577 Targeting PAX2 for the induction of DEFB1-mediated tumor immunity and cancer therapy  
Provided is a method of treating cancer in a subject by inhibiting expression of PAX2. An example of a cancer treated by the present method is prostate cancer. In the cancer treatment methods...
7964575 Use of a galectin-1-targeted RNAi-based approach for the treatment of cancer  
The present invention relates to an RNAi molecule suitable for reducing the expression of galectin-1 containing any of the sequences of SEQ ID NOs: 1-33, and preferably the sequences of SEQ ID NO:...
7964571 Combination of immuno gene therapy and chemotherapy for treatment of cancer and hyperproliferative diseases  
Pharmaceutical compositions comprising a nucleic acid, a gene delivery polymer, and at least one adjunctive chemotherapeutic drug for the treatment of mammalian cancer or hyperproliferative...
7964408 Lysophospholipids as biomarkers of ovarian cancer  
A method of using a bioactive lysophospholipid (LL) as a biomarker for detecting the presence and recurrence of ovarian cancer. Subspecies of LL, such as lysophosphatidic acid (LPA),...
7964400 Immune potentiating compositions of cancer cells  
A composition of matter is disclosed, comprising an immunostimulatory molecule and animal cells cultured in the presence of at least one interferon (IFN) for a time and under conditions sufficient...
7964365 Methods for diagnosing and monitoring the progression of cancer  
Methods for measuring c-Met levels in urine and blood samples are provided. Methods for diagnosis and prognosis evaluation for cancer are also provided.
7964349 Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments  
The present invention is directed to a method for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) treatment. In a preferred embodiment, the presence of at...
7960548 Keratinocyte growth factor receptor—tyrosine specific inhibitors for the prevention of cancer metastatis  
Compounds and methods for treating, inhibiting, or delaying the onset of cancer in a subject by administering a therapeutically effective amount of a keratinocyte growth factor receptor tyrosine...
7960527 Nucleic acid and corresponding protein entitled 151P3D4 useful in treatment and detection of cancer  
A novel gene (designated 151P3D4) and its encoded protein, and variants thereof, are described wherein 151P3D4 exhibits tissue specific expression in normal adult tissue, and is aberrantly...
7960435 Anti-cancer agents and androgen inhibition activity compound  
A qualitative 3D pharmacophore model (a common feature based model or Catalyst HipHop algorithm) developed from well-known natural product androgen receptor down-regulating agents (ARDAs). The 3D...
7960361 Nucleic acid cancer immunotherapy  
A method for stimulating a immune response against IL-13Rα2 in a subject having or at risk for developing a disease having cells expressing IL-13Rα2 includes the steps of formulating the a...
7960352 Anti-cancer activity of Androsace umbellata Merr. extract and contained triterpene saponin  
The present invention relates to an Androsace umbellata Merr. extract having anticancer activity and a triterpene saponin compound isolated therefrom, more particularly to an Androsace umbellata...
7960138 Method for prognosing response to cancer therapy with 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine  
Presented is a method of prognosing a patient's response to a cancer therapy wherein prior to the therapy contacting a sample of cells from the patient's tissue or organ being treated for the...
7960126 Immunoregulation in cancer, chronic inflammatory and autoimmune diseases  
The present invention primarily relates to a method for analyzing the amount of immunoregulatory integrin binding factors and/or patient endogenous antibodies which are directed against such...
7960112 Gene methylation in cancer diagnosis  
The present invention provides DNA biomarker sequences that are differentially methylated in samples from normal individuals and individuals with cancer. The invention further provides methods of...