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7160865 |
Cancer treatment including glycolytic inhibitors
Glycolytic inhibitors are useful in the treatment of solid tumors by attacking anaerobic cells at the center on the tumor. 2-deoxyglucose, oxamate and various analogs thereof are identified as...
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7160716 |
Device for inducing an immune response in cancer therapy
A device for inducing an immune response in cancer therapy in which isolated living malignant tissue is enclosed in a space formed by a microporous membrane and a holder which is introduced into a...
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7160697 |
Use of novel cytokine receptors as biomarkers and therapeutic targets in human cancer
Nucleic acids encoding erythropoietin isoforms are described herein, as well as the encoded isoforms, methods of detecting the same, and methods of screening for and treating cancer.
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7160679 |
Method of diagnosing, monitoring, and staging lung cancer
The present invention provides a new method for detecting, diagnosing, monitoring, staging, and prognosticating lung cancer.
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7160239 |
Method of breaking cancer cell tissue by microelectromagnetic radiation and microelectromagnetic radiator
A means and apparatus for breaking non-cellular tissues such as cancer cells to be used in medical treatments for human or animal body wherein heat energy is generated due to electric field energy...
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7157551 |
Compositions and methods for the detection and treatment of methylthioadenosine phosphorylase deficient cancers
Compositions and methods involving agents that specifically bind to methylthioadenosine phosphorylase (MTAP) protein are disclosed. Illustrative compositions comprise binding agents that bind to...
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7157438 |
Rhob as a suppressor of cancer cell growth and cell transformation
The protein RhoB and its variants as a supressor of cancer cell growth, inhibitor of malignant cell transformation, and modulator of oncogenic signaling, wherein introducing RhoB directly, or...
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7153946 |
Molecular conjugates for use in treatment of cancer
A molecular conjugate is provided having the formula:
wherein R 1 is a de-hydroxyl or de-amino moiety respectively of a hydroxyl-bearing or amino-bearing biologically active molecule or an...
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7153940 |
C-type lectin transmembrane antigen expressed in human prostate cancer and uses thereof
A novel gene (designated PC-LECTIN) that is highly overexpressed in prostate cancer and its encoded protein is described. PC-LECTIN in normal human tissues is restricted to testis, but is highly...
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7153875 |
Heterocyclic derivatives for the treatment of cancer and other proliferative diseases
The invention relates to certain heterocyclic compounds useful for the treatment of cancer and other diseases, having the Formula (I):
wherein:
(a) m is an integer 0 or 1; (b) R 12 is...
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7153700 |
Methods and compositions for diagnosing and predicting the behavior of cancer
The present invention relates to methods for detecting the presence of SIX1 protein or nucleic acid in a biological sample in which a biological sample is contacted with an agent capable of...
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7153653 |
Differentially methylated sequences in pancreatic cancer
The present invention provides a method for detecting a cellular proliferative disorder in a subject. The method includes contacting a nucleic acid-containing specimen from the subject with an...
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7153506 |
Use of anti-ferritin monoclonal antibodies in the treatment of some cancers
The invention concerns the use, in the preparation of a medicine for treating cancer whereof the cells exhibit overexpression of a product of a gene of the myc-related family, of an anti-ferritin...
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7151100 |
Indole compounds useful for the treatment of cancer
The present invention provides novel indole derivatives useful to inhibit cancer or sensitize cancer cells to chemotherapeutic agents, radiation or other anti-cancer treatments.
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7151099 |
Use of taurolidine and/or taurultam for treatment of abdominal cancer and/or for the prevention of metastases
Taurolidine and/or taurultam is administered during and after surgical removal of a cancerous tumor to treat abdominal cancer.
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7150869 |
Modified cytokines for use in cancer therapy
Cytokine derivatives capable of homing the tumoral vessels and the antigen presenting cells and the use thereof as antitumoral agents.
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7148337 |
C-type LECTIN transmembrane antigen expressed in human prostate cancer and uses thereof
A novel gene (designated PC-LECTIN) that is highly overexpressed in prostate cancer and its encoded protein is described. PC-LECTIN in normal human tissues is restricted to testis, but is highly...
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7148252 |
Use of benzopyranones for treating or preventing a primary brain cancer or a brain metastasis
This invention relates to methods for using benzopyranones, or their pharmaceutically acceptable salts, for treating or preventing a primary brain cancer or a brain metastasis. The benzopyranones...
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7148201 |
Use of human plasma hyaluronidase in cancer treatment
The invention is based on the discovery of methods for purification of an acid active hyaluronidase found in human plasma (hpHAse), including both biochemical and immunoaffinity purification...
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7148200 |
Method for treating cancer
A method for treating a cancer. The cancer excluding an adenocarcinoma and being epithelioma, glioma, sarcoma, melanoma, lymphoma or leukemia; or the cancer is an adenocarcinoma cancer excluding...
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7148038 |
Antibodies that bind to cancer-associated antigen CD46 and methods of use thereof
Provided herein is disclosure about the development and characterization of an antibody (mPA7) which binds to antigen CD46 which is present on a variety of human cancers from ovary, breast, lung,...
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7148009 |
Cancer drug screen based on cell cycle uncoupling
Checkpoint gene-defective human cells are useful for screening potential anti-tumor agents. Potential therapeutic agents are screened for the ability to cause DNA accumulation or cell death in a...
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7147848 |
Recombinant poliovirus for the treatment of cancer
The present invention is directed to non-pathogenic, oncolytic, recombinant polioviruses for the treatment of various forms of malignant tumors. The recombinant polioviruses of the invention are...
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7144912 |
Pyrrole-type compounds, compositions, and methods for treating cancer, treating viral diseases and causing immunosuppression
The present invention relates to novel Pyrrole-Type compounds, compositions comprising Pyrrole-Type compounds, and methods useful for treating or preventing cancer or a neoplastic disorder...
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7141576 |
Cancer treatment method
A method of treating cancer is described including administration of a 4-quinazolineamine and at least one other anti-neoplastic agent as well as pharmaceutical combinations and compositions...
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7138428 |
Compounds isolated from gamboge resin having activity in inhibiting the growth of tumor/cancer cells and pharmaceutical compositions comprising the same
Disclosed herein are an acetone-extracted product obtained from gamboge resin and compounds further purified from said acetone-extracted product, including a new compound called formoxanthone A....
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7138383 |
Treating cancer using an oligonucleotide N3′->N5′ thiophosphoramidate
Oligonucleotides with a novel sugar-phosphate backbone containing at least one internucleoside 3′-NHP(O)(S − )O-5′ linkage, and methods of synthesizing and using the inventive...
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7135549 |
Nucleic acid and corresponding protein entitled 184P1E2 useful in treatment and detection of cancer
A novel gene (designated 184P1E2) and its encoded protein, and variants thereof, are described wherein 184P1E2 exhibits tissue specific expression in normal adult tissue, and is aberrantly...
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7135547 |
Peptide conjugated anti-cancer prodrugs
The present invention relates to pharmaceutical compositions that include a targeting peptide, a protease specific cleavable peptide, and a chemotherapeutic drug that when conjugated are...
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7135463 |
RHoB as a suppressor of cancer cell growth, cell transformation, and metastasis
The present invention concerns the use of the protein RhoB and its variants to inhibit cancer cell growth, migration, invasion, metastasis, malignant cell transformation, and/or to modulate...
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7135333 |
Compositions that specifically bind to colorectal cancer cells and methods of using the same
A unique transcription product, CRCA-1, and alternative translation products generated therefrom, are disclosed. The transcript and its translation products are markers for colorectal cells....
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7135301 |
Detection and treatment of prostate cancer
An antigen is shown to be associated with prostate cancer, and is useful for new methods and compositions for diagnosing or treating prostate cancer. This is particularly useful for individuals...
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7135188 |
Methods and compositions for immunotherapy of cancer
Methods and vaccines for suppressing formation of or inhibiting growth of tumors in a host are provided, via administration of a vaccine containing either a fusion protein of the tumor associated...
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7132554 |
Therapeutic synergy of anti-cancer compounds
This invention relates to a synergistic therapeutic combination of anti-cancer compounds which comprises a) a taxane, and b) a substance that binds to the epidermal growth factor receptor (EGFR)...
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7132510 |
Specific human antibodies for selective cancer therapy
The present invention is directed to novel peptides and polypeptides that specifically bind to target cells and may have anti-cancer activity, especially blood-related cancers. The present...
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7132507 |
Isolated cancer associated antigens NY-MEL 1 and NY-MEL 3, peptides based thereon, and their uses
The invention relates to isolated, cancer associated antigens, nucleic acid molecules, and various uses thereof.
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7129377 |
Irreversible non-steroidal antagonist compound and its use in the treatment of prostate cancer
The present invention relates to an androgen receptor alkylating compound, wherein the compound may include, inter alia, an active functional group, which permits the alkylation of the androgen...
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7129366 |
Group of a novel anti-cancer compounds with specific structure
Compounds containing a specific saturated or unsaturated branched chain terminal group; a polar leading group; and a long-chain aliphatic, non-cyclic, saturated or unsaturated, substituted or...
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7129262 |
Indole compounds useful for the treatment of cancer
The present invention provides novel indole derivatives useful to inhibit cancer or sensitize cancer cells to chemotherapeutic agents, radiation or other anti-cancer treatments.
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7129230 |
Method and product for treating cancer in pets
A pet food containing vitamin D analogs for use in treatment of cancer in pets, such as dogs and cats, is described. Also described is a method for treating pets, such as dogs and cats, for cancer...
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7128877 |
Methods and devices for obtaining and assaying mammary fluid samples for evaluating breast diseases, including cancer
Non-invasive methods are provided for obtaining biological samples of mammary fluid or mammary fluid components by administering oxytocin to a patient to stimulate expression of mammary fluid....
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7125969 |
ETS-related gene overexpressed in human breast and epithelial cancers
This invention provides for a cDNA that is a coding region of a previously unknown member of the ETS transcription regulator family. The gene described herein (designated ESX) is located at...
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7125902 |
Methods, compounds, and diagnostics for cancer treatment
Methods of treating cancer employing isoxazole derivatives are described. Compounds and methods of using these compounds for isolating and/or detecting binding proteins, which may be indicative of...
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7125858 |
Hyaluronic acid in the treatment of cancer
The present invention relates to a composition and method comprising purified HA, a second anti-neoplastic agent and a pharmaceutically acceptable carrier, wherein the purified HA and the second...
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7125836 |
Method of cancer screening; method of cancer treatment; and method of diabetes treatment
A method of cancer screening comprising the steps of administering the Blood CA 27,29 testing procedure; if the result is positive administering a mammogram; if the result is positive...
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7125663 |
Genes, compositions, kits and methods for identification, assessment, prevention, and therapy of cervical cancer
The invention relates to newly discovered nucleic acid molecules and proteins associated with cervical cancer including pre-malignant conditions such as dysplasia. Compositions, kits, and methods...
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7122714 |
Mouse models of human prostate cancer
The present invention provides an immune deficient mouse having a human prostate xenograft of locally advanced or metastatic prostate cancer and uses thereof.
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7122030 |
Ferroelectric hyperthermia system and method for cancer therapy
A method of localized cell heating introduces a plurality of ferroelectric comprising particles into a target region of a patient, and applies a time varying electrical field to the target region....
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7119074 |
Treatment of cancers, tumors and malignancies using amphiphilic prodrugs
The present invention provides amphiphilic prodrugs comprising a therapeutic compound conjugated to an PEG-oligomer/polymer and methods for using said prodrugs to enable oral drug delivery and/or...
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7118853 |
Methods of classifying, diagnosing, stratifying and treating cancer patients and their tumors
The invention provides a variety of reagents for use in the diagnosis and management of breast cancer. The invention utilizes cDNA microarray technology to identify genes whose expression profile...
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