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9752196 Detection of chromosomal abnormalities associated with prognosis of non small cell lung cancer  
The methods and compositions described herein address the need for a diagnostic method that can be provided to patients with early stage lung cancer, especially non-small cell lung cancer (NSCLC),...
9751934 Monoclonal antibodies against claudin-18 for treatment of cancer  
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric...
9751859 Process for preparing an anti-cancer agent, 1-((4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)methyl)cyclopropanamine, its crystalline form and its salts  
The present invention relates a new process to synthesize 1-((4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxyquinolin -7-yloxy)methyl)cyclopropanamine (AL3818). A stable crystalline form of...
9750954 Concurrent delivery of interstitial thermobrachytherapy (hyperthermia and brachytherapy) in the treatment of cancer  
A system combines hyperthermia and radiation treatments in a single treatment modality by using a radioactive seed having magnetic, ferromagnetic, or ferrimagnetic properties.
9750951 Liquid type plasma for preventing or treating cancer  
The present invention relates to a method for preparing a plasma for preventing or treating a cancer. Also, the present invention relates to a liquid type plasma for preventing or treating a...
9750823 Use of a truncated CCN1 promoter for cancer diagnostics, therapeutics and theranostics  
Recombinant vectors in which expression of one or more elements (e.g. genes required for viral replication, detectable imaging agents, therapeutic agents, etc.) is driven by a truncated CCN 1...
9750809 Cancer treatment  
A carborane-comprising porphyrin of Formula (1) is provided for use in cancer therapy that extends the period of time between the doses required while the patient is undergoing radiation therapy....
9750807 Combination of local and systemic immunomodulative therapies for melanoma and liver cancer  
A method for the treatment of cancer comprising administration of a therapeutically effective amount of an intralesional chemoablative pharmaceutical composition, or variant of said composition,...
9750758 Compositions and methods for treating cancer with aberrant lipogenic signaling  
The technology described herein relates to pinacolyl boronate substituted stilbenes for the treatment of cancers, e.g. cancers expressing abnormally high levels of SREBP1. Exemplary pinacolyl...
9750741 Targeted therapies for cancer  
Methods of selecting a chemotherapy regimen for treatment of cancer in a patient are disclosed. A patient genetic sample from a bilary cancer such as cholangiocarcinoma is analyzed for a mutation...
9746480 Human myeloid derived suppressor cell cancer markers  
Provided herein are methods for determining the presence of cancer (malignant versus benign), monitoring the progression of cancer, monitoring cancer relapse, monitoring the response to cancer...
9746477 Quantifying FR-α and GART proteins for optimal cancer therapy  
Improved methods are provided for treating cancer patients, particularly patients suffering from lung cancer. Methods are provided for identifying whether a lung tumor will be responsive to...
9746473 ELISA detection of urine DEK to predict and diagnose bladder cancer in humans  
The present invention is directed to a method of detecting a DEK protein in a human urine sample using an ELISA assay. Methods and compositions for detection of DEK using mAb 260-6F9F6 (as...
9746472 Methods and kits for the detection of cancer infiltration of the central nervous system  
This invention relates to methods to detect the presence of cancer infiltration of the Central Nervous System (CNS) based on the detection of soluble proteins, preferably, in cerebrospinal fluid...
9745635 Recurrent gene fusions in prostate cancer  
Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and...
9745634 Systems and methods for diagnosing and treating cancer  
This invention identifies and provides a recurrent translocation t(4;8) (p16.2; p23.1) associated with certain cancers and other abnormal cell growth disorders and diagnostic methods using the...
9745632 Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers  
Mitochondrial DNA deletions useful for the detection of cancers and sun exposure are provided. In particular, methods and kits for detecting mitochondrial DNA deletions for the early detection,...
9745631 Methods for diagnosing and treating oncogenic kras-associated cancer  
Methods for diagnosing and treating cancer associated with an oncogenic Kras mutation in a subject are provided.
9745630 MiRNA fingerprint in the diagnosis of prostate cancer  
MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in...
9745622 Method for detecting the methylation of colorectal-cancer-specific methylation marker genes for colorectal cancer diagnosis  
The present invention relates to a method for detecting the methylation of colorectal cancer-specific marker genes for colorectal cancer diagnosis, and more particularly to a method of detecting...
9745578 Targeting microRNA miR-409-3P to treat prostate cancer  
The present invention describes methods of treating cancer, cancer metastasis, and drug resistant cancers using miRNA inhibitors; for example, inhibitors of miR-409-5p, miR-409-3p, miR-154*. Also...
9745377 Immunological compositions as cancer therapeutics  
The present invention concerns antibodies that react immunologically with an epitope comprising VDKSRWQQG (SEQ ID NO: 1), including those that bind to cancer cells, and methods relating thereto....
9745348 Short designed peptides possessing selective actions against bacteria and cancer cells  
The present invention relates to amphiphilic peptides having antibacterial and/or antitumor activity, and to therapeutic and non-therapeutic compositions comprising these peptides. The peptides...
9745288 Compounds and methods for treating cancer by inhibiting the urokinase receptor  
Compounds and methods for treating or preventing cancer associated with binding to the urokinase receptor are provided. Biological processes affected by the compounds include cell migration, cell...
9745278 Group of STAT3 pathway inhibitors and cancer stem cell pathway inhibitors  
The present invention relates to the use of a novel class of cancer stem cell pathway (CSCP) inhibitors; to methods of using such compounds to treat refractory, recurrent, or metastatic cancers;...
9744380 Patient specific beam control assembly of a cancer therapy apparatus and method of use thereof  
The invention comprises a patient specific tray insert removably inserted into a tray frame to form a beam control tray assembly, which is removably inserted into a slot of a tray receiver...
9744224 Methods for treating cancer by administration of nucleic acids encoding FAP and cancer antigens  
A immunogenic composition is provided for use in methods for treating or preventing the development of a cancer, comprising a nucleic acid sequence encoding a cancer antigen and a nucleic acid...
9744223 Therapeutic cancer vaccine targeted to HAAH (aspartyl-[asparaginyl]-β-hydroxylase)  
The present invention encompasses a cancer vaccine therapy targeting Aspartyl-[Asparaginyl]-β-hydroxylase (HAAH). The present invention contemplate bacteriophage expressing HAAH peptide fragments...
9744212 Galectin-3C combination therapy for human cancer  
The present invention provides a novel composition of matter useful for the treatment of neoplastic diseases. The novel composition is synergistic and comprised of galectin-3C in combination with...
9744206 Pharmaceutical compositions for treating cancer of genital system and preparation method therefor  
A pharmaceutical composition for preventing and treating cancer of reproductive system and preparation method therefor. The pharmaceutical composition is prepared using one or more of the...
9744205 Alcohol extract of dehulled adlay seeds for treating breast cancer  
The present invention provides a method for treating breast cancer in a subject, which comprises administering to said subject an effective amount of an alcohol extract of dehulled adlay seeds....
9744175 Compositions of combinations of non-covalent DNA binding agents and anti-cancer and/or anti-inflammatory agents and their use in disease treatment  
The invention provides for compositions for treating a cancer or an inflammatory disorder comprising a combination of agents in a pharmaceutically acceptable carrier, wherein said agents comprise:...
9744172 Pyrazolopyrimidine compounds for the treatment of cancer  
Compound of Formula I: are described, along with pharmaceutically acceptable salts thereof, compositions containing the same, and methods of use thereof in the treatment of cancer.
9744145 Methods for treating lung cancer  
This invention provides a method of treating lung cancer including administering a therapeutically effective amount of a compound of 0089-0022 formula I to a subject in need thereof. The compound...
9743836 Excitation, detection, and projection system for visualizing target cancer tissue  
A system visually distinguishes diseased tissue from healthy tissue after a treatment is administered to a patient to provide different concentrations of a fluorescent marking substance between...
9739784 Giant obscurins and uses thereof in cancer prognosis and therapy  
Provided herein are methods and kits for evaluating potential for invasiveness, metastasis, or recurrence of an epithelial cell cancer. In the methods the expression profile of giant obscurins is...
9739783 Convolutional neural networks for cancer diagnosis  
The present disclosure provides devices and systems for diagnosing and characterizing cancer in a subject. Devices include microfilters and microfiltration systems useful for the isolation and...
9739782 Methods and compositions for single chain variable region ENOX2 antibodies for cancer detection and diagnosis  
Cancers of different cellular or tissue origins express different ENOX2 cancer isoforms or combinations of isoforms and shed these proteins into the circulation. Herein are disclosed methods both...
9739780 Metabolite biomarkers for the detection of liver cancer  
Methods for the detection and screening of hepatocellular carcinoma (HCC) patients and for the monitoring of HCC treatment using a panel or panels of small molecule metabolite biomarkers are...
9738936 Breast cancer susceptibility gene GT198 and uses thereof  
It has been discovered that the human GT198 gene (gene symbol PSMC3IP) at chromosome 17q21 acts as a tumor suppressor. The mutation of the GT198 gene causes the increased dominant negative splice...
9737596 Vaccine for the prevention of breast cancer recurrence  
Provided are methods to induce and maintain a protective cytotoxic T-lymphocyte response to a peptide of the HER2/neu oncogene, GP2, with the effect of inducing and maintaining protective or...
9737540 Combination treatment of cancer  
The present invention relates to a combination comprising AZD5363, or a pharmaceutically acceptable salt thereof, and at least one androgen receptor signalling modulator selected from MDV-3100...
9737535 Methods for treating cancer using TOR kinase inhibitor combination therapy comprising administering substituted pyrazino[2,3-b]pyrazines  
Provided herein are methods for treating or preventing a cancer, comprising administering an effective amount of a TOR kinase inhibitor and an effective amount a second active agent to a patient...
9737488 Pharmaceutical composition for the treatment of cancer  
The present invention pertains to a pharmaceutical composition comprising the compound of the formula (I) in a high concentration and at least one pharmaceutically acceptable excipient, the use of...
9737272 Charged particle cancer therapy beam state determination apparatus and method of use thereof  
The invention comprises an apparatus and method of use thereof for determining a charged particle beam state after passage through a final beam modification insert and prior to entering a patient,...
9733187 Method of detecting bladder cancer by optical analysis of bodily fluids  
The method of detecting bladder cancer by optical analysis of bodily fluids utilizes optical techniques to determine a concentration of porphyrin in a patient's bodily fluid sample. The patient is...
9732389 Methods and compositions for correlating genetic markers with prostate cancer risk  
The present invention provides methods of assessing an individual subject's risk of developing prostate cancer, comprising: a) analyzing a nucleic acid sample obtained from the subject and...
9732139 Methods of treating cancer by administering a soluble receptor comprising a human Fc domain and the Fri domain from human frizzled receptor  
The present invention relates to compositions and methods for characterizing, diagnosing, and treating cancer. In particular the invention provides the means and methods for the diagnosis,...
9732131 Identification and use of novopeptides for the treatment of cancer  
Compositions, methods, systems, apparatus and/or articles of manufacture are disclosed for reducing the susceptibility of a population and/or members thereof to cancer, which may include...
9732114 Compounds having anti-adhesive effects on cancer cells  
Compounds of the form O-(x-L)n, where O is an oligonucleoside having at least a plurality of N3′→P5′ thiophosphoramidate (NPS) internucleoside linkages, a conjugated lipid moiety L, and at least...