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7982015 |
Compositions and methods for treatment of cancer
The present invention concerns compositions and methods for the treatment of disorders characterized by the overexpression of an LIV-1. More specifically, the compositions include DNA and amino...
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7982004 |
Nucleic acid and corresponding protein entitled 161P5C5 useful in treatment and detection of cancer
A novel gene (designated 161P5C5) and its encoded protein, and variants thereof, are described wherein 161P5C5 exhibits tissue specific expression in normal adult tissue, and is aberrantly...
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7981939 |
Application of 2-bromide-isovanillin for the manufacture of a medicament for anti-cancer or/and radiation/chemotherapy sensitization
Use of 2-bromo-isovanillin in the preparation of an anticancer medicament and/or radio- and chemotherapy sensitizing medicament is disclosed. The medicament for the treatment of cancers and/or for...
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7981903 |
2-[2-{phenylamino}-1H-pyrrolo[2,3-D]pyrimidin-4-yl)amino] benzamide derivatives as IGF-1R inhibitors for the treatment of cancer
Novel pyrrolopyrimidines as shown in formula (I): and pharmaceutically acceptable derivatives thereof. The compounds are useful in the inhibition of IGF-1R.
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7981625 |
Prostate cancer glycan markers and autoantibody signatures
Disclosed are methods for probing the immunogenic sugar moieties of prostate cancer cells. The methods detect a number of glyco-epitopes that are highly and differentially expressed among prostate...
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7981618 |
Diagnostic and therapeutic methods and compositions involving PTEN and breast cancer
Patients with ErbB2-overexpressing cancers can be given an ErbB2 targeting agent as a therapeutic regimen but not all patients are responsive. The present invention concerns the diagnostic,...
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7981613 |
Diagnosis kits and method for detecting cancer using polymorphic minisatellite
The present invention relates to a kit and a method for diagnosing cancer using polymorphic minisatellites (MS), more specifically, relates to a primer set for detecting polymorphic minisatellites...
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7981603 |
Methods for identifying cancer risk
The present invention provides methods and kits for identifying an increased risk of developing cancer in a subject. The methods include analyzing a first biological sample, such as a blood sample,...
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7977372 |
Ortho aminoamides for the treatment of cancer
Compounds of formula are HDAC inhibitors. These compounds are useful for the treatment of diseases such as cancer in humans or animals.
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7977369 |
Medical compositions for intravesical treatment of bladder cancer
Methods for treating bladder cancer comprising intravesicular administration of a stabilized pharmaceutical formulation comprising...
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7977062 |
Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer
A novel gene 0161P2F10B (also designated 161P2F10B) and its encoded protein, and variants thereof, are described wherein 161P2F10B exhibits tissue specific expression in normal adult tissue, and is...
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7976854 |
Method of treating skin requiring skin cancer treatment
A treatment regimen for treating skin subject to skin cancer treatments involves the application of supplemental composition(s) such as preparatory composition(s), protective composition(s), and...
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7976852 |
Compositions and methods for cancer immunotherapy
The invention relates to immunotherapeutic compounds and to methods for stimulating an immune response in a subject individual at risk for developing cancer, diagnosed with a cancer, in treatment...
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7976846 |
Stress protein compositions and methods for prevention and treatment of cancer and infectious disease
Pharmaceutical compositions comprising a stress protein complex and related molecules encoding or cells presenting such a complex are provided. The stress protein complex comprises an hsp110 or...
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7976842 |
Treatment of metastatic breast cancer
The present invention relates to the use of an anti-EpCAM antibody for the manufacture of a medicament for the treatment of metastatic breast cancer. The present invention further relates to a...
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7976825 |
Cancer cell diagnosis by targeting delivery of nanodevices
Macromolecular contrast agents for magnetic resonance imaging are described. Biomolecules and their modified derivatives form stable complexes with paramagnetic ions thus increasing the molecular...
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7973135 |
Compositions and methods for targeting cancer-specific transcription complexes
The invention provides molecules that target cancer-specific transcription complexes (CSTC), compositions and kits comprising CSTC-targeting molecules, and methods of using CSTC-targeting molecules...
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7973017 |
Treatment of cancer by inhibition of IGFBP's and clusterin
Agents that reduce the amount of IGFBP-2 and/or IGFBP-5 and that are known to be useful in the treatment of cancer result in increased expression of the protein clusterin. Since clusterin can...
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7972817 |
Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer
This invention relates to the use of extracellular ribonucleic acid (RNA) found circulating in the plasma or serum fraction of blood. Specifically, this invention enables the extraction of...
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7972774 |
Methods of diagnosing cervical cancer
The invention provides reagents and methods for detecting pathogen infections in human samples. This detection utilizes specific proteins to detect the presence of pathogen proteins or abnormal...
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7972772 |
KIF11 and method for diagnosing non-small cell lung cancer
Disclosed are methods for detecting non-small cell lung cancer (NSCLC) using differentially expressed genes KIF11, GHSR1b, NTSR1, and FOXM1. Also disclosed are methods of identifying compounds for...
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7972770 |
Methods of detection of cancer using peptide profiles
The disclosed methods address the identification and monitoring of cancer in a subject using serum peptide profiles. Such profiles allow the detection of the differential presence of certain serum...
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7972609 |
Method of treating cancer
Present invention relates to the method of treating cancer. According to present invention, a pharmaceutical composition made from ‘Mycobacterium w’ (Mw) is found to be useful in the management of ...
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7972600 |
IGF-IR antagonists as adjuvants for treatment of prostate cancer
The present invention relates to a method of treating prostate cancer with androgen deprivation therapy and an insulin-like growth factor receptor (IGF-IR) antagonist. Although the response rate of...
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7968738 |
Compounds and methods for the treatment of cancer
The present invention provides organic arsenicals. Many of these compounds have potent in vitro cytotoxic activity against numerous human tumor cell lines, both of solid and hematological origin,...
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7968531 |
Use of 2,5-dihydroxybenzenesulphonic acid in the production of medicaments for the treatment of angiodependent diseases such as cancer and psoriasis
The invention relates to the use of 2,5-dihydroxybenzenesulfonic acid in the production of medicaments for the treatment of angiodependent diseases. More specifically, the invention relates to the...
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7968526 |
Antisense oligonucleotides directed to ribonucleotide reductase R2 and uses thereof in the treatment of cancer
The present invention provides antisense oligonucleotides directed to a mammalian ribonucleotide reductase R2 gene and combinations of the antisense oligonucleotides with one or more...
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7968514 |
Pharmaceutical composition for treating or preventing ovarian cancer
The invention relates to therapeutic and prophylactic treatment of ovarian cancer and metastases thereof. More specifically, the invention relates to immunogenic polypeptides comprising at least a...
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7968294 |
SLIT2 underexpression in metastatic prostate cancer
This invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, this invention relates to SLIT2 cancer...
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7968283 |
Gene expressed in prostate cancer
A novel testis-specific gene expressed in human prostate cancer, designated 22P4F11, is described. Analysis of 22P4F11 mRNA expression in normal prostate, prostate tumor xenografts, and a variety...
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7968281 |
Methods of modulating SMYD3 for treatment of cancer
The present invention features a method for determining the methyltransferase activity of a polypeptide and screening for modulators of methyltransferase activity, more particularly for modulators...
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7968115 |
Liposomal curcumin for treatment of cancer
The present invention provides a compositions and methods for the treatment of cancer, including pancreatic cancer, breast cancer and melanoma, in a human patient. The methods and compositions of...
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7968099 |
Nucleic acid and corresponding protein entitled 193P1E1B useful in treatment and detection of cancer
A novel gene (designated 193P1E1B) and its encoded protein, and variants thereof, are described wherein 193P1E1B exhibits tissue specific expression in normal adult tissue, and is aberrantly...
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7968090 |
Nucleic acids and corresponding proteins entitled 191P4D12(b) useful in treatment and detection of cancer
A novel gene 191P4D12(b) and its encoded protein, and variants thereof, are described wherein 191P4D12(b) exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in...
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7964717 |
RNAi probes targeting cancer-related proteins
RNAi sequences that are useful as therapeutics in the treatment of cancers of various types, including prostate cancer, sarcomas such as osteosarcoma, renal cell carcinoma, breast cancer, bladder...
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7964577 |
Targeting PAX2 for the induction of DEFB1-mediated tumor immunity and cancer therapy
Provided is a method of treating cancer in a subject by inhibiting expression of PAX2. An example of a cancer treated by the present method is prostate cancer. In the cancer treatment methods...
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7964575 |
Use of a galectin-1-targeted RNAi-based approach for the treatment of cancer
The present invention relates to an RNAi molecule suitable for reducing the expression of galectin-1 containing any of the sequences of SEQ ID NOs: 1-33, and preferably the sequences of SEQ ID NO:...
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7964571 |
Combination of immuno gene therapy and chemotherapy for treatment of cancer and hyperproliferative diseases
Pharmaceutical compositions comprising a nucleic acid, a gene delivery polymer, and at least one adjunctive chemotherapeutic drug for the treatment of mammalian cancer or hyperproliferative...
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7964408 |
Lysophospholipids as biomarkers of ovarian cancer
A method of using a bioactive lysophospholipid (LL) as a biomarker for detecting the presence and recurrence of ovarian cancer. Subspecies of LL, such as lysophosphatidic acid (LPA),...
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7964400 |
Immune potentiating compositions of cancer cells
A composition of matter is disclosed, comprising an immunostimulatory molecule and animal cells cultured in the presence of at least one interferon (IFN) for a time and under conditions sufficient...
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7964365 |
Methods for diagnosing and monitoring the progression of cancer
Methods for measuring c-Met levels in urine and blood samples are provided. Methods for diagnosis and prognosis evaluation for cancer are also provided.
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7964349 |
Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments
The present invention is directed to a method for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) treatment. In a preferred embodiment, the presence of at...
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7960548 |
Keratinocyte growth factor receptor—tyrosine specific inhibitors for the prevention of cancer metastatis
Compounds and methods for treating, inhibiting, or delaying the onset of cancer in a subject by administering a therapeutically effective amount of a keratinocyte growth factor receptor tyrosine...
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7960527 |
Nucleic acid and corresponding protein entitled 151P3D4 useful in treatment and detection of cancer
A novel gene (designated 151P3D4) and its encoded protein, and variants thereof, are described wherein 151P3D4 exhibits tissue specific expression in normal adult tissue, and is aberrantly...
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7960435 |
Anti-cancer agents and androgen inhibition activity compound
A qualitative 3D pharmacophore model (a common feature based model or Catalyst HipHop algorithm) developed from well-known natural product androgen receptor down-regulating agents (ARDAs). The 3D...
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7960361 |
Nucleic acid cancer immunotherapy
A method for stimulating a immune response against IL-13Rα2 in a subject having or at risk for developing a disease having cells expressing IL-13Rα2 includes the steps of formulating the a...
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7960352 |
Anti-cancer activity of Androsace umbellata Merr. extract and contained triterpene saponin
The present invention relates to an Androsace umbellata Merr. extract having anticancer activity and a triterpene saponin compound isolated therefrom, more particularly to an Androsace umbellata...
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7960138 |
Method for prognosing response to cancer therapy with 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine
Presented is a method of prognosing a patient's response to a cancer therapy wherein prior to the therapy contacting a sample of cells from the patient's tissue or organ being treated for the...
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7960126 |
Immunoregulation in cancer, chronic inflammatory and autoimmune diseases
The present invention primarily relates to a method for analyzing the amount of immunoregulatory integrin binding factors and/or patient endogenous antibodies which are directed against such...
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7960112 |
Gene methylation in cancer diagnosis
The present invention provides DNA biomarker sequences that are differentially methylated in samples from normal individuals and individuals with cancer. The invention further provides methods of...
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