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9771618 Methods for treating breast cancer  
Clinical tests for testing therapeutic sensitivity of cancerous breast tissue and methods and kits for performing the same are described herein. Embodiments of the present invention are directed...
9771411 Method of treating cancer by administering EGFR and EGFR/IGFIR binding molecules  
The present invention relates to bispecific molecules comprising an EGFR binding domain and a distinct IGFIR binding domain for use in diagnostic, research and therapeutic applications. The...
9771404 Multi-level specific targeting of cancer cells  
A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13Rα2 binding ligand; at least one effector molecule (e.g., one, two, three or more...
9771356 Inhibitors of beta-hydroxylase for treatment of cancer  
The present invention relates to compounds which modulate (e.g., inhibit) the activity of beta-hydroxylase (e.g., Asparatyl (asparaginyl) β-hydroxylase (ASPH)), including novel...
9771347 Process for making compounds for use in the treatment of cancer  
Disclosed herein is a process of making a compound of formula I The compound of formula I is an inhibitor of MEK and thus can be used to treat cancer.
9771330 Pyrimidine compounds for the treatment of cancer  
Compounds of Formula I or II: are described, along with pharmaceutical compositions containing the same and methods of using such compounds for the treatment of cancer.
9770499 MSI-specific frameshift peptides (FSP) for prevention and treatment of cancer  
Described is a vaccine for prevention and treatment of cancer characterized by microsatellite instability (MSI). The vaccine contains an MSI-specific frameshift peptide (FSP) generating humoral...
9770482 Targeting the EGFR-SGLT1 interaction for cancer therapy  
A compound can destabilize an epidermal growth factor receptor (EGFR) protein and a sodium/glucose co-transporter 1 (SGLT 1) protein. In one embodiment, the compound is a peptide derived from the...
9770467 Compositions and methods for cancer immunotherapy  
The present invention provides a combination therapy which relies on a small molecule immune stimulator—cyclic-di-nucleotide (CDN)—that activates DCs via a recently discovered cytoplasmic receptor...
9770462 Method of treating ovarian, tubal and peritoneal cancer  
A method of treating ovarian, tubal and peritoneal cancer is revealed. It comprises administering an effective amount of a pharmaceutical composition (including a copper chelator, a platinum-based...
9770458 Anti-cancer agent containing a diacylphosphatidylethanolamine as an active ingredient  
The present invention provides an anti-cancer agent, a cancer cell death inducing agent, a protein phosphatase 2A activation enhancing agent, a protein tyrosine phosphatase 1B activation enhancing...
9770442 Self-assembling amphiphilic polymers as anti-cancer agents  
The invention provides amphiphilic biocompatible copolymers which have a hydrophilic backbone and pendant hydrophobic groups. The polymers form nanoscale molecular aggregates in aqueous...
9770414 Sustained release formulation of methotrexate as a disease-modifying antirheumatic drug (DMARD) and an anti-cancer agent  
Disclosed is are formulations comprising a multivesicular liposome and MTX, the administration of which results in a Cmax of MTX between 5% and 50% of the Cmax of an immediate release dosage form...
9770175 Apparatus and method for detecting a presence of cancer  
A method of examining breasts of a patient in an examination room to detect for potential breast cancer includes sliding a camera assembly along a rail between a pair of rail ends on a horizontal...
9766245 Method of detecting cancer based on glycan biomarkers  
The present invention provides a method for labeling or detecting a protein with certain glycosyl groups. The methods are particularly useful for detecting cancer cells comprising the detected...
9766244 Diagnosis and monitoring treatment of prostate cancer  
Provided herein are assays and methods related to determining a ratio of expression levels of PSA/PSMA or determining the expression level of PSMA in circulating tumor cells for diagnosis and/or...
9765401 Frizzled 2 as a target for therapeutic antibodies in the treatment of cancer  
Disclosed herein are methods of treating cancer in a subject, and methods for inhibiting growth, migration and/or invasion of a cancer cell in the subject, comprising administering to the subject...
9765337 Phosphoribosyl pyrophosphate synthetase 2 (PRPS2) as a therapeutic target in cancer treatment  
The present invention provides methods of selectively killing a cell, comprising contacting the cell with an agent that inhibits phospho-ribosyl pyrophophosphate synthetase 2 (PRPS2). The present...
9765334 Compositions and methods for prognosis of gastric cancer  
Described herein are compositions and methods for survival prediction in gastric cancer patients after surgical operation. The compositions are microRNA molecules associated with the prognosis of...
9765187 MRI contrasting agent for contrasting cancer cell  
The present invention relates to MRI contrasting agent for contrasting cancer cell which contains ultrafine nanoparticles. More particularly, the present invention is directed to a self-assembled...
9765147 Anti-CSFR1 antibody and anti PD-1 antibody combination therapy for cancer  
Methods of treating cancer with antibodies that bind colony stimulating factor 1 receptor (CSF1R) in combination with PD-1/PD-L1 inhibitors are provided.
9765118 Pharmaceutical composition for cancer prevention and treatment containing peptide originated from C12orf59 protein as an active ingredient  
As explained hereinbefore, the C12orf59 gene of the present invention suppresses cancer cell invasion and inhibits cancer cell survivability, and the over expression of C12orf59 protein or a...
9765117 Peptides for treating cancer  
Provided are novel peptides having a human minute binding protein-2 (HDM-2) targeting sequence that target the human minute binding protein-2. Also provided are fusion proteins comprising an HDM-2...
9765114 Method for cancer immunotherapy  
A novel compound of the formula (1): wherein X is a tyrosine residue or a methionine residue; Y and Z each are a single bond or the like; R1 is a hydrogen atom or the like; R2 is a hydroxy group...
9765113 Methods and agents for the treatment of cancer  
There are disclosed methods for prophylaxis or treatment of cancer in a mammal. The methods comprise administering an effective amount of an agent to the mammal, which binds to a MAP kinase or an...
9765061 Trail enhancers for the selective killing of cancer cells  
The invention is directed to methods of inducing apoptosis, arresting cell cycle, or inhibiting cellular proliferation, or any combination thereof, in a tumor cell, by administration of an...
9764035 Methods and compositions for treating prostate cancer  
Treatment of prostate cancer by regional and prolonged release of one or more nucleotide-based RNAi agents is provided.
9764005 Suppression of cancer metastasis  
Methods of using fibrillar proteins are provided for suppressing cancer metastasis. Cancer metastasis is the most common cause of treatment failure and death in cancer patients. Tumor cell...
9763982 Depletion of cancer stem cells  
Compositions and methods are provided for killing of cancer stem cells, and for the transplantation of pluripotent stem cells and differentiated cells derived therefrom.
9763956 Diagnostic and treatment methods in subjects having or at risk of developing resistance to cancer therapy  
The invention relates to methods of treatment and diagnosis of subjects with cancer. In some aspects, the invention relates to methods of treatment and diagnosis of subjects with cancer, wherein...
9763946 Inhalation-type pharmaceutical composition for the treatment of lung cancer and preparation method thereof  
The present invention provides an inhalation-type pharmaceutical composition for lung cancer and preparation method thereof, comprising a first gas and an atomized medicine. The first gas...
9763915 Adjuvants in anti-cancer chemotherapy  
The present invention provides a 1,2,4-trioxane or a pharmaceutically acceptable salt, ester, solvate, tautomer or stereoisomer thereof for use as an adjuvant for a tyrosine kinase inhibitor to...
9763910 Combination therapy for treating cancer  
Disclosed is a method of treating a subject having non-small cell lung cancer. The method includes administering to the subject a therapeutically effective amount of a composition and the...
9763881 Rice bran-lipids based formulation and process for preparation thereof for selective delivery of genes to cancer cells  
The present invention relates to a formulation in which glycolipids and phospholipids, isolated from rice bran gum samples, were used in conjunction with gene carrying lipids to test its efficacy...
9760760 Histology recognition to automatically score and quantify cancer grades and individual user digital whole histological imaging device  
Digital pathology is the concept of capturing digital images from glass microscope slides in order to record, visualize, analyze, manage, report, share and diagnose pathology specimens. The...
9759725 Treatment-induced damage to the tumor micro-environment promotes cancer therapy resistance through extracellular proteins  
The present disclosure provides methods for determining the effectiveness of a cancer therapy, as well as methods for increasing the effectiveness of that therapy and determining a prognosis for a...
9758834 Compositions and methods for diagnosing cancer  
The application describes methods for diagnosing subjects with leukemia by detecting fusion genes associated with the onset of leukemia.
9758827 miRNA fingerprint in the diagnosis of lung cancer  
The present invention provides novel methods for diagnosing diseases based on the determination of specific miRNAs that have altered expression levels in disease states compared to healthy controls.
9758786 Compositions and methods for treating pancreatic cancer  
Provided herein are composition for sensitizing tumors to anti-tumor therapies. The compositions include antisense oligonucleotides against TGFβ2, wherein the compositions sensitize tumors to...
9758580 Uses of antibodies to interleukin-6 in cancer treatment  
The present disclosure provides antibodies that bind to human interleukin-6 (IL6). The antibodies can modulate IL6 signaling and thus used in treatment or prevention of IL6 associated diseases or...
9758495 Heteroaryl acid morpholinone compounds as MDM2 inhibitors for the treatment of cancer  
The present invention provides MDM2 inhibitor compounds of Formula (I), or the pharmaceutically acceptable salts thereof, wherein the variables are defined above, which compounds are useful as...
9757594 Rotatable targeting magnet apparatus and method of use thereof in conjunction with a charged particle cancer therapy system  
A rotatable targeting magnet apparatus and method of use thereof is described where the rotatable targeting magnet rotates independently of a beamline arc at the end of the beamline arc, where the...
9757458 Crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in hematopoietic cancer cells  
Extensive crosslinking of CD22 by plate-immobilized epratuzumab induced intracellular changes in Daudi cells similar to ligating B-cell antigen receptor (BCR) with a sufficiently high amount of...
9757457 Use of 2-deoxy-D-glucose to sensitize cancer cells to an agent that activates the extrinsic apoptotic pathway  
Methods for sensitizing a solid tumor cell to an agent that activates the extrinsic apoptotic pathway and treating a solid tumor using a combination of 2-deoxy-D-glucose and an agent that...
9757440 Method for treating cancer with Toxoplasma gondii vaccine  
The present invention provides attenuated Toxoplasma gondii mutants for use as vaccines in the prevention or treatment of cancer.
9757375 Compounds that inhibit human DNA ligases and methods of treating cancer  
Methods for treating cancer using compounds that inhibit human DNA ligases. Methods for using compounds that inhibit human DNA ligases to provide insights into the reaction mechanisms of human DNA...
9753043 Methods and algorithms for aiding in the detection of cancer  
A method of data interpretation from a multiplex cancer assay is described. The aggregate normalized score from the assay is transformed to a quantitative risk score quantifying a human subject's...
9753038 Method for detecting cancer via measurement of caprin-1 expression level  
This invention provides: a method for detecting a cancer, comprising measuring the expression of a polypeptide having binding reactivity through antigen-antibody reaction with an antibody against...
9753037 Biomarker panel for detecting lung cancer  
A method and a kit for assessing risk of lung cancer versus benign disease in a subject are provided. The method includes obtaining a biological sample from the subject and determining a...
9752197 Method for detecting methylation of colorectal cancer specific methylation marker gene for colorectal cancer diagnosis  
The present invention relates to a method for detecting methylation of the bowel-cancer-specific methylation marker GPM6A (NM_201591, glycoprotein M6A) gene in order to diagnose bowel cancer, and...