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9688665 Methods of treating cancer  
The present invention relates to methods of treating cancer by administering the EZH2 inhibitor compounds and pharmaceutical compositions to subjects in need thereof. The present invention also...
9688640 Methods of treating cancer with a pyrazole derivative  
There is provided a compound of formula (I): or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a...
9687668 Treatment of cancer in body cavities and parts that are cavity-like  
The Body Cavity Cancer Treatment System achieves extremely uniform temperatures inside the tissue of the body cavity thereby realizing optimal efficacy in enhancing operation of the chemotherapy...
9687500 Methods and compositions for treating cancer  
Treatment of cancer by regional and prolonged release of one or more nucleotide-based agents is provided.
9687469 Agent containing flavonoid derivatives for treating cancer and inflammation  
A pharmaceutical composition for the prevention and treatment of cancer with specific flavanoid-based compounds selected from among the groups of Flavone, Flavanone and Flavanol, a method for the...
9687464 Anti-cancer agent delivery vehicles capable of improved loading  
There is provided a conjugate of a delivery agent containing a chemical moiety and at least one flavonoid. The flavonoid exists in a monomeric form or dimeric form before conjugation and remains...
9687458 Trans-clomiphene for use in cancer therapy  
The present invention relates to the administration of compositions comprising an antiestrogen, preferably a selective estrogen receptor modulator (SERM) such as trans-clomiphene, for treating...
9683995 Method of treatment of SETDB1 expressing cancer  
Provided herein are methods for diagnosing cancer by determining the level of expression of SETDB1 in a biological sample. Also provided herein are methods for treating cancer by administering an...
9683987 Gastric cancer cell line derived from murine gastric adenocarcinoma lacking p53 and E-cadherin and use thereof  
Provided is a gastric cancer cell line derived from a mouse deficient in E-cadherin and p53, and a use thereof. The E-cadherin- and p53-deficient, murine-derived gastric cancer cell line of the...
9683986 Treatment of cancer by inhibition of the MYD88/ERK MAP kinase interaction  
A method for selecting in vitro compounds is capable of potentiating the effect of a DNA damage inducing chemotherapy agent for the treatment of cancer, and includes selecting compounds inhibiting...
9683039 Notch agonists for the treatment of cancer  
The present invention is directed to methods of treating and preventing acute myeloid leukemia and acute myeloid leukemia relapse disease in a subject that involve administering a Notch receptor...
9683025 Methods and compositions for treating cancer and inflammatory diseases  
The invention provides a peptide construct comprising a cell penetrating peptide and an inhibitory peptide that interferes with the interaction between E1A and CtBP. The invention also provides...
9682996 Alpha helix mimetic compositions for treating cancer and other CBP/catenin-mediated diseases and conditions  
Alpha-helix mimetic structures and compounds represented by the formula (I) wherein the general formula and the definition of each symbol are as defined in the specification, a compound relating...
9682947 Substituted lactones for treating cancer  
Novel heterocyclo compounds represented by Formula I wherein X, R1, R2, R3, R4, R5, R6 and n are as described herein are provided. The compounds may be prepared as pharmaceutical compositions, and...
9682926 Cancer chemotherapeutic agent/formulation, manufacture and use thereof  
A cancer chemotherapeutic agent that is particularly kinase suppressing and/or any other signaling pathway interfering agents and pharmaceutical formulations/compositions involving the same and...
9682254 Cancer surface searing apparatus and method of use thereof  
The invention comprises a charged particle cancer therapy system used to seal a periphery of a tumor, such as through use of a proton or carbon ion beam searing the outer edges of the tumor, which...
9682247 Apparatus for the generation of an energy field for the treatment of cancer in body cavities and parts that are cavity-like  
The body cavity cancer treatment apparatus generates the magnetic field for use in a combined “low temperature hyperthermia” and ionizing radiation and/or chemotherapy cancer treatment protocol....
9682090 Methods for treating and preventing prostate cancer bone metastases  
Methods for treating a subject having a prostate cancer bone metastasis are disclosed. Methods for prophylactically treating a subject at risk of developing a prostate cancer bone metastasis are...
9682063 HCD formulation for cancer treatment  
The present invention provides a novel formulation for cancer treatment and a method for enhancing the HCD's efficacy in cancer treatment. Specifically, the present invention provides...
9678077 ERG/TFF3/HMWCK triple immunostain for detection of prostate cancer  
This invention relates to a triple immunostaining assay (ERG/TFF3/HMWCK) for sensitive and specific detection of prostate cancer. Positive staining for at least one of ERG or TFF3 combined with...
9678075 Prediction of recurrence for bladder cancer by a protein signature in tissue samples  
The present invention pertains to the field of cancer prediction. Specifically, it relates to a method for predicting the risk of recurrence of bladder cancer in a subject after treatment of...
9677140 Molecular diagnostic test for cancer  
Methods and compositions are provided for the identification of a molecular diagnostic test for cancer. The test defines a novel DNA damage repair deficient molecular subtype and enables...
9677139 Genetic markers indicative of a cancer patient response to trastuzumab (herceptin)  
The invention relates to the fields of therapeutics and identifying candidates for therapy, in particular to a method of identifying candidates for trastuzumab (Herceptin®) therapy in a patient...
9677072 Methods of inhibiting proliferation of estrogen-independent cancer cells  
The invention relates to methods of inhibiting the growth or proliferation of a cell, the method comprising reducing the expression or activity of at least one gene in the cell selected from the...
9676862 Anti-CD40 antibodies and methods of treating cancer  
The present invention relates to antibodies (and fragments, variants, fusions and derivatives thereof) with multivalent binding specificity for CD40, which have a potency for dendritic cell...
9676828 Rearranged TT virus molecules for use in diagnosis, prevention and treatment of cancer and autoimmunity  
The present invention relates to rearranged molecules of (a) a specific TT virus sequence and (b) a nucleotide sequence encoding a polypeptide showing homology to mammalian proteins associated...
9676813 Certain steroids and methods for using the same in the treatment of cancer  
Chemical entities that are novel compounds, pharmaceutical compositions and methods of treatment of cancer are described.
9676788 Aza-epoxy-guaiane derivatives and treatment of cancer  
Disclosed is a compound of formula (I) or formula (II): (Formulas should be inserted here) wherein R1-R6 are as defined herein. Also disclosed are a pharmaceutical composition comprising such a...
9676774 Compounds and compositions for treatment of cancer  
Compounds and compositions for treating, preventing or managing cancer are disclosed. The compositions provided herein comprise SNS-595 and N-desmethyl-SNS-595. Also provided are pharmaceutical...
9676749 Compositions and methods for cancer detection and treatment  
Disclosed herein are compositions and methods for cancer detection and treatment. Compounds that inhibit PRMT5 are contemplated, as are pharmaceutical compositions comprising a therapeutically...
9675747 Methods and systems for improved cavitation efficiency and density, cancer cell destruction, and/or causing a target object to be a cavitation nucleus  
A method of causing an object to act as a cavitation nucleus comprising the steps of providing a sound energy source capable of generating a sound energy over a plurality of frequency ranges,...
9675673 Transluminal delivery of oncoltyic viruses for cancer therapy  
Methods, apparatus and compositions are provided for treatment of cancer of a selected organ by intraluminal delivery of oncolytic agents through a blood vessel or duct leading to the cancer...
9675654 Phytocannabinoids in the treatment of cancer  
This invention relates to the use of phytocannabinoids, either in an isolated form or in the form of a botanical drug substance (BDS) in the treatment of cancer. Preferably the cancer to be...
9675642 Engineered dendritic cells and uses for the treatment of cancer  
This invention provides the field of therapeutics. Most specifically present invention provides methods of generating in vitro engineered dendritic cells conditionally expressing interleukin-12...
9675633 miRNA for treating cancer and for use with adoptive immunotherapies  
In some aspects, miRNA for the treatment of cancer are provided. In some embodiments, a miRNA (e.g., miR-124, miR-142, and/or miR-138) may be used to promote or enhance immune destruction of a...
9675620 MAO inhibitors and their conjugates as therapeutics for the treatment of brain cancer  
A pharmaceutical composition and method for treating brain cancer are provided. The method includes administering to a patient in need thereof an effective amount of one or more compounds that...
9675596 1,2,4-thiazolidin-3-one derivatives and their use in the treatment of cancer  
According to the invention there is provided a compound of formula (I) wherein: A represents C(═N—W-D) or S; B represents S or C(—NH—W-D); when: A represents C(═N—W-D) and B represents S then the...
9675586 Estrogen receptor modulator for the treatment of locally advanced or metastatic estrogen receptor positive breast cancer  
Described herein are methods of treating locally advanced or metastatic estrogen receptor positive breast cancer.
9675578 Breast cancer therapy based on hormone receptor status with nanoparticles comprising taxane  
The present invention relates to methods and kits for the treatment of breast cancer based on hormone receptor status of progesterone receptor and estrogen receptor comprising the administration...
9675576 Polyenolic zinc-binding agents (pezbins) actively promote inactivation of cancer stem cells and potentiate cytotoxic anti-tumor drug substances  
The present invention provides a method of inhibiting the growth of or promoting differentiation and destruction of cancer stem cells (CSCs) comprising contacting the cancer stem cells with a...
9675563 Method for adjunctive treatment of cancer metastasis by using lycogen  
The present invention relates to a method for adjunctive treatment of cancer by using a Lycogen composition to inhibit metastasis, comprising administering a Lycogen composition to the subject,...
RE46423 Compositions of engineered human arginases and methods for treating cancer  
Compositions and methods for the treatment of cancer are described, and, more preferably, to the treatment of cancers that do not express, or are otherwise deficient in, argininosuccinate...
9672329 Methods and apparatuses for predicting risk of prostate cancer and prostate gland volume  
Methods and apparatuses for predicting risk of prostate cancer and/or prostate gland volume are provided. More particularly, this disclosure relates to methods and apparatuses for providing the...
9671413 Prostate cancer point of care diagnostics  
The invention relates to point of care diagnostic disposables, devices, methods, and systems for diagnosing or predicting prostate cancer. The present invention employs biomarker specific reagents...
9671405 Identifying taxane sensitivity in prostate cancer patients  
The invention relates to detection and/or treatment of a subset of prostate cancer patients who may benefit from taxane treatment. The method comprises testing whether an androgen receptor (AR)...
9671404 Use of myeloid cell biomarkers for the diagnosis of cancer  
The present invention relates to the use of myeloid cell biomarkers for the differential diagnosis, prognosis, and monitoring of renal cell carcinoma (RCC) or colorectal cancer (CRC). The present...
9670552 Diagnosis kit and chip for bladder cancer using bladder cancer specific methylation marker gene  
The present invention relates to a kit and nucleic acid chip for diagnosing bladder cancer using a bladder cancer-specific marker gene. More particularly, the invention relates to a kit and...
9670551 Diagnosis kit and chip for bladder cancer using bladder cancer specific methylation marker gene  
The present invention relates to a kit and nucleic acid chip for diagnosing bladder cancer using a bladder cancer-specific marker gene. More particularly, the invention relates to a kit and...
9670548 Methods of diagnosing colorectal cancer by detecting FADA expression  
A method of identifying a subject with increased risk of colorectal cancer includes obtaining a biological sample from the subject, measuring the level of Fusobacterium nucleatum in the biological...
9670547 Molecular diagnostic test for cancer  
Methods and compositions are provided for the identification of a molecular diagnostic test for cancer. The test defines a novel DNA damage repair deficient molecular subtype and enables...