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7205108 |
Trp8, Trp9 and Trp10, novel markers for cancer
The present invention relates to gene expression in normal cells and cells of malignant tumors and particularly to novel markers associated with cancer, Trp8, Trp9 and Trp10, and the genes encoding...
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7204996 |
Method of cancer treatment
This invention comprises a method of treating a subject having relapsed or refractory cancer such as leukemia with liposomal annamycin including the steps of
(a) evaluating the subject to...
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7204987 |
Biological compositions and methods for treatment of prostate cancer
The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with prostate cancer. The...
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7204982 |
Compositions and methods for treatment and detection of multiple cancers
The invention provides a method for inhibiting proliferation of cancer cells, as well as methods for detecting and treating various cancers, including cancer of the brain, lung, breast, prostate...
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7202342 |
Compositions and methods for the therapy and diagnosis of prostate cancer
Compositions and methods for the therapy and diagnosis of cancer, such as prostate cancer, are disclosed. Compositions may comprise one or more prostate-specific proteins, immunogenic portions...
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7202334 |
Compositions and methods for the therapy and diagnosis of ovarian cancer
Compositions and methods for the therapy and diagnosis of cancer, such as ovarian cancer, are disclosed. Compositions may comprise one or more ovarian carcinoma proteins, immunogenic portions...
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7202045 |
Detection and treatment of cancers of the lung
The present invention relates to compositions and methods for cancer therapies and diagnostics, including but not limited to, cancer markers. In particular, the present invention provides tumor...
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7201928 |
Extracts of orange peel for prevention and treatment of cancer
Compositions and methods of inhibiting tumor cell growth and treating and preventing cancer are provided based on administration of an orange peel extract either alone or in combination with other...
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7201924 |
Method for cancer therapy using herbal extracts
A new method is described for the treatment of cancer. In one alternative, the method utilizes two main compositions. The first composition is Soma, a healing herb described in the Rig Veda, the...
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7201905 |
Bi-functional cancer treatment agents
A novel fusion protein, comprising a receptor-antagonizing domain and a positive immunomodulator domain, characterized, for example, by its ability to block apoptosis and/or inhibit endocrine...
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7200203 |
Devices and methods for targeting interior cancers with ionizing radiation
Devices and related methods are provided for irradiating a portion of a body. A device according to one embodiment can include a radiation needle, a fluorescent target, and an x-ray transmitting...
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7199220 |
103P2D6: tissue specific protein highly expressed in various cancers
A novel gene (designated 103P2D6) and its encoded protein are described. 103P2D6 is not expressed in normal adult tissue, but is highly expressed in prostate tissue xenografts, providing evidence...
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7199218 |
ICBP90 polypeptide and its fragments and polynucleotides coding for said polypeptides and applications for diagnosing and treating cancer
The invention concerns a novel ICBP90 (Inverted CCAAT box binding protein 90) and its fragments, polynucleotides coding for said polypeptides and specific antibodies directed against said...
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7198899 |
Use of NRG4, or inhibitors thereof, in the treatment of colon and pancreatic cancers
This invention relates to compositions and uses of NRG4, and to variants thereof and to polynucleotides encoding NRG4, for therapeutic and diagnostic purposes, particularly related to colon and...
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7196070 |
Prophylactic and therapeutic treatment of the ductal epithelium of a mammary gland for cancer
The present invention provides prophylactic and therapeutic methods of treating the ductal epithelium of an exocrine gland, in particular a mammary gland, for disease, in particular cancer. The...
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7196068 |
Method for treating cancer using p38/JTV-1 and method for screening pharmaceutical composition for treating cancer
The present invention relates to a method for treating cancer using p38/JTV-1 and a method for screening pharmaceutical composition for treating cancer. More particularly, this invention relates to...
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7195868 |
Compositions and methods for the identification, assessment, prevention, and therapy of human cancers
The present invention is directed to the identification of markers that can be used to determine whether tumors are sensitive or resistant to a therapeutic agent. The present invention is also...
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7195764 |
Cancerous disease modifying antibodies
The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer...
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7193040 |
Polypeptide for the treatment of cancer and a method for preparation thereof
This invention characterizes the specific peptide fragment derived from specially prepared zinc charged fetuin and a method of preparation thereof, wherein the fragment was found to contain an...
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7192709 |
Methods for identification, assessment, prevention, and therapy of cancer
The present invention relates to the newly identified cancer therapeutic targets and biomarkers. These targets/biomarkers are overexpressed in carcinomas generally, and more specifically to...
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7192704 |
Methods for detection and treatment of neural cancers
The invention provides a method for inhibiting proliferation of neural cells. The neural cells can be tumor cells, glial cells, neuronal cells, and cells of the central or peripheral nervous...
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7192698 |
EphA2 as a diagnostic target for metastatic cancer
Method and kits are provided for the detection and diagnosis of metastatic disease. More particularly, the methods and kits employ compounds that can detect EphA2, a specific epithelial cell...
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7192612 |
Compositions and methods based on synergies between capsicum extracts and tea catechins for prevention and treatment of cancer
The invention described herein encompasses methods and compositions of preventing or treating cancer comprising the administration of a combination of therapeutically effective amount of catechins,...
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7189833 |
Prostate cancer gene
The present invention relates to PG1, a gene associated with prostate cancer. The invention provides polynucleotides including biallelic markers derived from PG1 and from flanking genomic regions....
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7189825 |
Cancerous disease modifying antibodies
The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer...
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7189712 |
1,3-Oxazole compounds for the treatment of cancer
Oxazole derivatives, which are useful as VEGFR2, CDK2, and CDK4 inhibitors are described herein. The described invention also includes methods of making such oxazole derivatives as well as methods...
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7189551 |
Human RPS6KA6-related gene variant associated with lung cancers
The invention relates to the nucleic acid and polypeptide sequences of a novel human RPS6KA6-related gene variant (RPS6KA6V). The invention also provides a process for producing the polypeptide of...
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7189507 |
Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
Described herein are genes whose expression are up-regulated or down-regulated in ovarian cancer. Related methods and compositions that can be used for diagnosis and treatment of ovarian cancer are...
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7186808 |
Cancerous disease modifying antibodies
The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer...
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7186713 |
Farnesyl dibenzodiazepinones and methods of treating cancer using same
This invention relates to methods of inhibiting growth of a cancer cell and methods of treating cancer using a novel farnesylated dibenzodiazepinone.
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7186699 |
Method for treating cancer by vector-mediated delivery of one or more anti-angiogenic or pro-apoptotic genes
The present invention provides therapeutic compositions and methods for vector-mediated delivery and in vivo expression of polynucleotides encoding anti-cancer compounds that are effective in the...
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7186537 |
Human GAK-related gene variants associated with lung cancer
The invention relates to the nucleic acid and polypeptide sequences of two novel human GAK-related gene variants. The invention also relates to the process for producing the polypeptides of the...
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7186517 |
Compositions and methods for monitoring breast cancer treatment
The present invention provides compositions and a method for monitoring breast cancer treatment.
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7186509 |
Detection of a genetic predisposition to cancers in cats
Methods are provided for the detection of susceptibility to cancer and non-cancerous pathologies in a mammal. Diagnostic kits are also provided.
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7183400 |
Use of ULIP proteins in the diagnosis and therapy of cancers and paraneoplastic neurological syndromes
The invention concerns a purified polypeptide, biologically active polypeptide derivative or fragment of said purified polypeptide, comprising an amino acid sequence selected among SEQ.ID. No. 2,...
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7183389 |
Monoclonal antibodies and cell surface antigens for the detection and treatment of small cell lung cancer (SCLC)
The invention provides new monoclonal antibodies and binding fragments thereof which recognize and immunoreact with cell surface antigens found on small cell lung cancer (SCLC) cells. The...
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7183384 |
Monoclonal antibody 7H11 reactive with human cancer
Novel monoclonal antibodies and binding fragments thereof specific to human breast cancer, lung cancer, colon cancer and other cancers. The monoclonal antibody does not bind to the cell surface of...
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7183258 |
Two synthetic peptides for treatment and prevention of cancers
Two synthetic peptides, Atroporin (AT) and Kaotree (KT), each consisting of ten amino acids and their use for the treatment and/or prevention of various types of cancers is disclosed. The amino...
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7183257 |
Use of RPL41 to treat infections and inhibit cancer
The present invention relates to peptides of RPL41 and their use in the treatment of cancer and microbial infections. It is contemplated that modified forms of RPL41, including substitutional...
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7183251 |
hCG therapy for the treatment of breast cancer
This invention relates to the field of cancer therapy. More particularly, the invention relates to the treatment of mammary tumor, clinically manifest mammary tumor (breast cancer) and metastatic...
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7183051 |
Diagnosis and treatment of cancer
The invention is based on the elucidation of a mechanism by which HPV promotes oncogenesis and provides a methods of diagnosing malignant tumors and methods of preventing the development of...
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7182962 |
Immunostimulator for animals and humans, and method of preventing animal and human infectious diseases and cancer
The goal of the present invention is to provide substances to prevent diseases by activating inherently possessed functions, for cultured fishes and shellfishes and livestock with tendency of...
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7179937 |
Cyclopentenone derivatives for cancer therapy
The invention relates to the use of derivatives of cyclopentenone for the inhibition or prevention of the growth or multiplication of cancer cells, and to therapeutic compositions containing such...
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7179912 |
Materials and methods to potentiate cancer treatment
Compounds that inhibit DNA-dependent protein kinase, compositions comprising the compounds, methods to inhibit the DNA-PK biological activity, methods to sensitize cells the agents that cause DNA...
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7179797 |
Methods and compositions for treating prostate cancer using DNA vaccines
A DNA vaccine for the treatment of prostate cancer, comprising a plasmid vector comprising a nucleotide sequence encoding prostatic acid phosphatase (PAP) operably linked to a transcription...
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7176315 |
Enantiomers of 6-[(4-chloro-phenyl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-methyl]-4-[3-(3-hydroxy-3-methyl-but-1-ynyl)-phenyl]-1-methyl-1H-quinolin-2-one and salts thereof, useful in the treatment of cancer
This invention relates to the enantiomers of 6-[(4-chloro-phenyl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-met
hyl]-4-[3-(3-hydroxy-3-methyl-but-1-ynyl)-phenyl]-1-methyl-1
H-quinolin-2-one, prodrugs...
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7176293 |
Compositions and methods to enhance sensitivity of cancer cells to mitotic stress
An isolated nucleic acid sequence of a mitotic checkpoint gene, chfr, encodes a Chfr protein having a Forkhead-associated domain and a Ring Finger. This protein is required for regulation of the...
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7176020 |
EBV-infected stomach cancer cell line
An EBV strain infecting epithelial cells and a stomach cancer cell line cancerated by EBV are established to clarify the mechanism of canceration of epithelial cells into stomach cancer by EBV and...
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7175981 |
Method of diagnosing stage or aggressiveness of breast and prostate cancer based on levels of fatty acid binding proteins
A method of diagnosing the stage or aggressiveness of cancer and particularly breast and prostate cancer by measuring the deviation of levels of fatty acid binding proteins in mammalian tissue or...
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7175846 |
Cancerous disease modifying antibodies
The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer...
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