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9987326 Klotho protein and related compounds for the treatment and diagnosis of cancer  
Disclosed is the use of a klotho protein or related compounds for the diagnosis and treatment of cancer, alone or together with other active pharmaceutical ingredients such as chemotherapeutic...
9987278 Pharmaceutical composition for treating FLT3 mutation-positive cancer, mutant FLT3 inhibitor and uses thereof  
Provided are a pharmaceutical composition for treating an FLT3 mutation-positive cancer; a mutant FLT3 inhibitor; and uses thereof. Disclosed are a pharmaceutical composition for treating an FLT3...
9987250 Compositions and methods for treating or preventing inflammatory bowel disease, familial adenomatous polyposis and colon cancer  
The present invention provides methods for preventing colon cancer by administering, to a patient in need thereof, a polymeric proanthocyanidin composition from a Croton species or Calophyllum...
9987241 Enzyme conjugate and prodrug cancer therapy  
A method and composition for treating a cancerous tumor in a subject by targeting the tumor's vasculature using an enzyme conjugate comprising a ligand which binds to endothelial cells in the...
9987089 Device and a method for imaging-guided photothermal laser therapy for cancer treatment  
This invention relates to a device and a method for monitoring and optimizing photothermal therapy, using a high-power continuous-wave laser beam and a pulsed laser beam, both transmitted through...
9984201 Method and system for determining cancer status  
Disclosed herein are methods, systems, platforms, non-transitory computer-readable medium, services, and kits for determining a cancer type in an individual. Also described herein include methods,...
9983209 Method of diagnosing, treating and determining progression and survival of cancer cells using BCL-2 antagonist of cell death (BAD) pathway gene signature  
The present invention relates to the BAD pathway's influence on development, progression, chemo-sensitivity, and overall survival for multiple human cancers and its potential as a therapeutic...
9983208 Composition for diagnosing pancreatic cancer and method for diagnosing pancreatic cancer using the same  
The present invention relates to: a composition for diagnosing pancreatic cancer, containing a preparation for measuring the expression level of a protein or a gene thereof, and capable of being...
9983194 Cancer diagnostics, therapeutics, and drug discovery associated with macropinocytosis  
The present invention is directed to methods of inhibiting both proliferation and survival of cancer cells and for treating a subject having cancer. The present invention is further directed to...
9982307 Methylation biomarkers for breast cancer  
Different combinations of methylation status based biomarkers can be used to test for breast cancer with high sensitivity and high specificity.
9982306 Somatic mutations in ATRX in brain cancer  
We determined the sequence of ATRX and DAXX in 447 cancers from various sites. We found mutations most commonly in pediatric glioblastoma multiformae (GBM) (11.1%), adult GBM (6.5%),...
9982305 Polymerase chain reaction test kits for detecting markers of bladder cancer  
This invention relates to the use of human neutrophil marker interleukin 8 receptor B (IL8Rb) for detection of bladder cancer, and more particularly to the use of EL8Rb for discriminating between...
9982304 ARID1A and PPP2R1A mutations in cancer  
Two genes, ARID1A (AT-rich interactive domain-containing protein 1A) and PPP2R1A (protein-phosphatase 2, regulatory subunit 1, alpha), can be used in methods which are useful for detecting cancer,...
9982043 Use of IL-20 antagonists for treating pancreatic cancer  
Methods for treating pancreatic cancer using an IL-20 antagonist, which can be an antibody that binds IL-20 or an IL-20 receptor, thereby blocking the signaling pathway mediated by IL-20.
9981974 Small molecules targeting androgen receptor nuclear localization and/or level in prostate cancer  
A method for treating prostate cancer in a subject, comprising administering a therapeutically effective amount of at least one agent to the subject, wherein the agent is selected from: (a) a...
9981968 Substituted pyrrolo[2,3-d]pyrimidines for the treatment of cancer and proliferative disorders  
Disclosed are substituted pyrrolo[2,3-d]pyrimidine compounds. The disclosed compounds are shown to be useful in inhibiting the growth of cancer cell lines and treating cancer and cell...
9981936 Isoflavonoid compositions and methods for the treatment of cancer  
Provided herein is a pharmaceutical composition comprising an isoflavonoid derivative and a cyclodextrin. Also provided herein are methods of treating cancer, sensitizing cancer cells, and...
9981915 Compounds for treatment of cancer  
The present invention relates to colchicine-binding site compounds having anti-cancer activity, compositions comprising the same, and their use for treating various forms of cancer.
9981042 Carbon nanotube-based anti-cancer agent capable of suppressing drug resistance  
The present invention provides an anticancer agent comprising a multi-walled carbon nanotube and an anticancer drug covalently attached to the surface of the multi-walled carbon nanotube, in order...
9980994 Myxoma virus mutants for cancer treatment  
Myxoma viruses that are deficient in the activity of a Myxoma virus protein selected from the group consisting of M11L, M063, M 136, M-T4 and M-T7 are useful for treating cancer.
9980966 Combinations of cancer therapeutics  
The invention relates to combinations of 4-[(S)-2-Azetidin-1-yl-1-(4-chloro-3-trifluoromethyl-phenyl) -ethylamino]-quinazoline-8-carboxylic acid amide and/or its physiologically acceptable salts...
9980963 Treatment of cancer with dihydropyrazino-pyrazines  
Provided herein are methods for treating or preventing chronic lymphocytic leukemia, comprising administering an effective amount of a Dihydropyrazino-Pyrazine Compound to a patient having chronic...
9980957 Histone deacetylase (HDAC) inhibitors for the treatment of cancer  
The present invention relates generally to methods for treating cancer. In one respect, the present invention relates to a method of treating a hematological cancer (e.g., multiple myeloma,...
9980953 Combined composition for preventing or treating cancer comprising a benzophenone thiazole derivatives as a VDA and topoisomerase inhibitor  
The present invention relates to a pharmaceutical combined composition for preventing or treating cancer comprising a compound of formula 1 or a pharmaceutically acceptable salt thereof and...
9980951 Image guided therapy for cancer  
The invention provides a method to treat cancer in an animal comprising administering a tetra-arylethylene cation to the animal.
9977033 Methods for assessing cancer recurrence  
Certain embodiments are directed to methods of identifying a subject having a higher risk of prostate cancer recurrence. The methods can include the step of measuring levels of one or more of...
9976188 Cancer biomarkers  
Biomarkers and methods using the biomarkers for the prediction of the recurrence risk of cancer in a patient are provided.
9976187 Methylation biomarkers for prostate cancer  
Different combinations of methylation status based biomarkers can be used to test for prostate cancer with high sensitivity and high specificity.
9974844 Cancer vaccine compositions and methods of using the same  
The present invention provides methods and compositions for the stimulation of immune responses. In particular, the present invention provides nanoemulsion compositions and methods of using the...
9974830 Molecular signature of cancer  
The present invention provides compounds, compositions, and methods for detecting, diagnosing and treating cancers such as glioblastoma multiforme.
9974766 Prenylated isoflavones for treatment of subjects with multidrug-resistant cancer  
Prenylated isoflavones are suitable to specifically inhibit P-glycoprotein in multidrug-resistant cancer cells leading to an accumulation of cytotoxic compounds or therapeutic compounds in the...
9974760 Compositions and methods for treating cancer  
The present invention provides, in part, compositions and methods for treating cancer using a combination of C6-ceramide and other anti-cancer agents.
9970937 Composition and method for diagnosis and immunotherapy of prostate cancer  
A method and composition for the diagnosis of and treatment of prostate cancer including a recombinant AKAP-4 tumor-associated antigen loaded antigen presenting cell that generates an AKAP-4...
9970012 Replication factor C-40 (RFC40/RFC2) as a prognostic marker and target in estrogen positive and negative and triple negative breast cancer  
The present disclosure relates generally to cancer and particularly to breast cancer including estrogen sensitive, estrogen resistant and triple negative breast cancer (TNBC), and to methods of...
9969781 Compositions and methods to treat cancer with CpG rich DNA and cupredoxins  
The present invention relates to compositions comprising CpG rich DNA from Pseudomonas aeruginosa. The compositions optionally comprise a cupredoxin. The present invention includes specific CpG...
9969715 Compounds useful for treating cancer  
The present invention relates to a compound of formula (I): wherein A and A′ independently represent a phenylene group or a pyridylene group; R2 is a hydrogen atom or a (C1-C4)alkyl group; R3 is a...
9969699 Cancer cell growth inhibitor, anticancer agent, and method for screening same, as well as novel compound  
A cancer cell proliferation inhibitor including at least one selected from compounds represented by Structural Formulae (1) to (8), wherein the cancer cell is at least one of a cancer cell...
9968685 Methods to treat cancer with cupredoxins  
The present invention discloses methods and materials for killing and/or inhibiting the growth of a cancer cell via preferential entry of a cytotoxic compound. Preferential entry of the cytotoxic...
9968619 Method of treating triple-negative breast cancer using thienotriazolodiazepine compounds  
A method of treating triple-negative breast cancer in a mammal comprising the step of: administering to a patient a pharmaceutical acceptable amount of a compound being a thienotriazolodiazepine...
9968606 Deuterated compounds for treating cancer and related diseases and conditions, and compositions and methods thereof  
The invention provides novel chemical compounds useful for treating cancer or a related disease or disorder thereof, and pharmaceutical composition and methods of preparation and use thereof.
9968570 Compositions and methods for treating cancer  
The present invention provides, in part, compositions and methods for treating cancer using a combination of C6-ceramide and other anti-cancer agents in certain vesicles.
9965585 Detection of genetic or molecular aberrations associated with cancer  
Systems, apparatus, and methods are provided for determining genetic or molecular aberrations in a biological sample. Biological samples including cell-free DNA fragments are analyzed to identify...
9964542 Bladder cancer detection composition, kit, and associated methods  
Compositions, kits, and methods for the diagnosis, prognosis, and monitoring of bladder cancer in a subject are provided by detecting in a urine sample a combination of biomarkers. In one...
9963747 Methods for the identification, assessment, and treatment of patients with cancer therapy  
The present invention is directed to the identification of predictive markers that can be used to determine whether patients with cancer are clinically responsive or non-responsive to a...
9963746 Composition or kit for making a prognosis of liver cancer, and method for making a prognosis of liver cancer  
The present disclosure provides a marker for predicting prognosis of liver cancer, a composition or kit for predicting prognosis of liver cancer, preferably, a composition or kit for predicting...
9963703 Compositions and methods for treating pancreatic cancer  
Provided herein are composition for sensitizing tumors to anti-tumor therapies. The compositions include antisense oligonucleotides against TGFβ2, wherein the compositions sensitize tumors to...
9963701 Pharmaceutical composition for treatment of radiation- or drug-resistant cancer comprising HRP-3 inhibitor  
The present invention relates to a pharmaceutical composition for treating a radiation- or drug-resistant cancer, containing an agent capable of inhibiting the expression of hepatoma-derived...
9963695 Diagnosis of prostate cancer  
The invention provides methods for isolating RNA from whole urine and urine fractions for the diagnosis of prostate cancer and/or benign prostate hyperplasia. An exemplary method for diagnosing...
9963486 Peptidomimetics for treating HER2-overexpressed cancer  
Novel peptidomimetic compounds are disclosed, compounds that inhibit protein-protein interactions (PPI) of epidermal growth factor receptors (EGFR), also called human epidermal growth factor...
9963485 Cycloheptapeptide agents for treatment of cancer and obesity diseases  
New anticancer and anti-obesity agents based on cyclic peptide compounds are isolated from the stem barks of Maytenus variabilis (Loes.) C. Y. Cheng (Celastraceae). The invention also includes its...