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7257437 |
Autofluorescence detection and imaging of bladder cancer realized through a cystoscope
Near infrared imaging using elastic light scattering and tissue autofluorescence and utilizing interior examination techniques and equipment are explored for medical applications. The approach...
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7256272 |
Individualized anti-cancer antibodies
The present invention relates to a method for producing patient specific anti-cancer antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell...
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7256271 |
Cancerous disease modifying antibodies
The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer...
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7256037 |
Modified vaccinia Ankara expressing p53 in cancer immunotherapy
Mutations to the tumor suppressor protein p53 have been observed in 40-60% of all human cancers. These mutations are often associated with high nuclear and cytoplasmic concentrations of p53. Since...
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7253209 |
Remedies for cisplatin-tolerant cancer
Preparation of a lipophilic platinum complex being dissolved or suspended in an iodized poppyseed oil fatty acid ethyl ester is useful as an agent for treatment of cisplatin-resistant cancers.
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7252976 |
Quantitative RT-PCR to AC133 to diagnose cancer and monitor angiogenic activity in a cell sample
The present invention involves the use of quantitative RT-PCR to identify AC133 as a marker. AC133 is prevalent on endothelial progenitor cells (EPCs), which are important cells in angiogenesis....
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7252955 |
Method of detecting colon cancer
An immunological assay and kit for colon cancer screening is disclosed. Fecal glycoproteins are extracted from individual samples such that immunogenicity is maintained. The purified fecal...
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7252935 |
Method of detection of prostate cancer
The present invention provides methods and kits useful for detecting neplasia by measuring the methylation level of biomarkers, especially the promoter region of GSTP1 for the detection of prostate...
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7252824 |
Anti-neovasculature preparations for cancer
Disclosed herein are immunogenic compositions, methods of designing immunogenic compositions, methods of treatment using immunogenic compositions, methods of evaluating cell-mediated immunity...
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7252821 |
Cancerous disease modifying antibodies
The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer...
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7250498 |
Nucleic acids and corresponding proteins entitled 273P4B7 useful in treatment and detection of cancer
A novel gene 273P4B7 and its encoded protein, and variants thereof, are described wherein 273P4B7 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the...
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7250492 |
Compositions and methods for inhibition of cancer invasion and angiogenesis
The invention provides antibodies that specifically bind a membrane protease complex, the complex consisting of two homodimers of seprase and dipeptidyl peptidase IV (DPPIV), obtained from...
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7250438 |
Anti-bacterial and anti-cancer spiro beta-lactone/gamma-lactams
Disclosed herein are novel spiro beta-lactone/gamma lactams for use in treating bacterial infections and cancer. The compounds are characterized by a terminal electron-withdrawing group such as a...
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7250435 |
Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents
The present invention relates to the synthesis of a new class of indeno[1,2-c]pyrazol-4-ones of formula (I):
that are potent inhibitors of the class of enzymes known as cyclin dependent...
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7250432 |
Pharmaceutical compositions of diaryl-isoxazole derivatives for the prevention and treatment of cancers
The present invention relates to a pharmaceutical composition for the prevention and the treatment of cancers containing diaryl-isoxazole derivatives as an effective ingredient. Diaryl-isoxazole...
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7250423 |
Methods for synthesizing heterocycles and therapeutic use of the heterocycles for cancers
The present invention provides methods for synthesizing novel tetrahydroquinoline derivatives that are useful for cancer chemotherapy and anti-viral applications. The present invention provides...
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7250180 |
Anti-prostate cancer composition and therapeutic uses therefor
Disclosed are methods and compositions useful in treating prostate cancer. The invention is based on BIRM, an extract of the plant Solanaceae - Dulcamara and its previously unrecognized...
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7247734 |
3,4-diarylpyrazoles and their use in the therapy of cancer
The present invention pertains to the use of certain 3,4-diarylpyazoles of formula (I), both in vitro and in vivo, to inhibit heat shock protein 90 (HSP90), and in the treatment of conditions...
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7247715 |
Ricin-like toxin variants for treatment of cancer, viral or parasitic infections
The present invention provides a protein having an A chain of a ricin-like toxin, a B chain of a ricin-like toxin and a heterologous linker amino acid sequence, linking the A and B chains. The...
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7247610 |
Use of glutamate antagonists for the treatment of cancer
Disclosed are methods for treating cancer by administering an inhibitor of the interaction of glutamate with the KA receptor complex.
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7247476 |
Individualized anti-cancer antibodies
The present invention relates to a method for producing patient specific anti-cancer antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell...
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7247444 |
Use of interleukin-19 to treat cervical cancer
The present invention relates to the anti-cancer activity of IL-19 polypeptide molecules. IL-19 is a cytokine involved in inflammatory processes and human disease. The present invention includes...
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7247426 |
Classifying cancers
The overexpression of certain marker genes including Wnt5a has been found useful in the identification of more aggressive forms of malignant melanoma. Therefore, the overexpression of these genes...
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7244827 |
Nucleic acid and corresponding protein entitled 24P4C12 useful in treatment and detection of cancer
A novel gene 024P4C12 (also designated 24P4C12) and its encoded protein, and variants thereof, are described wherein 24P4C12 exhibits tissue specific expression in normal adult tissue, and is...
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7244232 |
Process for identifying cancerous and/or metastatic cells of a living organism
A process for identifying and treating cells in a living organism. The cells are labeled, circulated within the organism, detected with an implanted detector, and then either isolated or ablated.
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7241876 |
Compositions and methods for the therapy and diagnosis of breast cancer
Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic...
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7241753 |
Method of treatment of prostate cancer
The present invention relates to the field of cancer, and in particular hormone dependent cancers including, but not limited to prostate, breast, endometrial, ovarian, thyroid, bone, and testis....
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7238662 |
Alpha 2HS glycoprotein for treatment of cancer and a method for preparation thereof
This invention characterizes the selective apoptotic activity of specially prepared Alpha 2-HS glycoprotein and fragments thereof. Specifically, Alpha 2-HS glycoprotein which has been overloaded...
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7238524 |
Prostate cancer cell lines
Novel human prostate cancer-associated neuroendocrine (NE)-like cell lines are provided that were derived via a process that resembles clinical androgen ablation therapy for advanced prostate cancer.
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7238471 |
Method of diagnosing, monitoring, staging, imaging and treating breast cancer
Diagnostic markers for breast cancer referred to herein breast cancer specific genes or BCSGs are provided. Also provided are methods for using BCSGs to detect, diagnose, monitor, stage,...
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7235695 |
Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
Conformationally restricted polyamine compounds useful in treatment of cancer and other diseases marked by abnormal cell proliferation are disclosed. Improved methods of synthesizing such compounds...
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7235403 |
Reagents and methods for identifying gene targets for treating cancer
The invention provides methods and reagents for identifying mammalian genes necessary for tumor cell growth as targets for developing drugs that inhibit expression of said genes and inhibit tumor...
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7235262 |
Use of bioactive fraction from cow urine distillate (‘Go-mutra’) as a bio-enhancer of anti-infective, anti-cancer agents and nutrients
The invention relates to a novel pharmaceutical composition comprising an effective amount of bio-active fraction from cow urine distillate as a bioavailability facilitator and pharmaceutically...
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7232655 |
Method and probe set for detecting cancer
Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset...
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7232653 |
Cancer cells from body fluids containing cells, isolation thereof and agents containing the same
The present invention relates to a method for isolating cancer cells from body fluids containing cells. The invention also relates to sets for carrying out said method, cancer cells isolated from...
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7232578 |
Pharmaceutical composition inducing cancer cell differentiation and the use for treatment and prevention of cancer thereof
The present invention relates to a pharmaceutical composition for the treatment and prevention of cancer and the preparation method thereof, especially to a cell differentiation agent named CDA-II...
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7231074 |
Method for determining the efficacy of an anti-cancer treatment using image analysis
An apparatus, system, method, and computer readable medium containing computer-executable code for implementing image analysis uses multivariate statistical analysis of sample images, and allows...
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7230139 |
Diterpenoid compounds, compositions thereof and their use as anti-cancer or anti-fungal agents
The present invention relates to Diterpenoid Compounds, compositions comprising an effective amount of a Diterpenoid Compound, and methods useful for treating or preventing cancer or a neoplastic...
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7229774 |
Expression profile of prostate cancer
The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides gene expression...
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7229770 |
YKL-40 as a marker and prognostic indicator for cancers
This invention provides methods for detecting cancers and for evaluating the prognosis of cancer patients. In particular, the methods of this invention utilize YKL-40 as a marker for the presence...
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7229617 |
Methods and compositions for inducing apoptosis in cancer cells
Anti-DR4 or Anti-DR5 antibody agonists, combined with apoptosis-inducing agents, synergistically induce apoptosis in cancer cells.
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7227008 |
13-transmembrane protein expressed in prostate cancer
A novel prostate tumor associated gene (designated 24P4C12) and its encoded protein is described. 24P4C12 is highly expressed in prostate tissue xenografts, providing evidence that it is turned on...
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7226750 |
Ovarian cancer cell and myeloma cell surface glycoproteins, antibodies thereto, and uses thereof
The present invention is directed to cell surface antigenes found on myeloma cells and on ovarian cancer cells that are recognized by monoclonal antibodies, and antibody binding fragments thereof,...
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7226731 |
PB 39, a gene dysregulated in prostate cancer, and uses thereof
A novel gene, PB39, that is up-regulated, or over-expressed, in prostate cancer has been identified. The gene has been identified by means of its cDNA obtained by reverse transcription of the...
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7226606 |
Cancer-associated antigens and methods of their identification and use
The present invention provides novel, isolated, tumor-associated antigens, and methods for identifying such antigens in a biological sample, and of screening for the presence of such an antigen in...
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7226594 |
Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer
A novel gene 0161P2F10B (also designated 161P2F10B) and its encoded protein, and variants thereof, are described wherein 161P2F10B exhibits tissue specific expression in normal adult tissue, and is...
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7225080 |
Diagnosis method of inflammatory, fibrotic or cancerous disease using biochemical markers
The present invention is drawn to a new diagnosis method for detecting the extend of a inflammatory, fibrotic or cancerous disease in a patient, in particular liver fibrosis, in particular in a...
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7223580 |
N-acetylglucosamine transferase, nucleic acid encoding the same and use thereof in diagnosing cancer and/or tumor
An enzyme having an activity of transferring N-acetylglucosamine to the non-reducing end of a Galβ1-4Glc or Galβ1-4GlcNAc-group via a β-1,3 bond; a nucleic acid encoding the same; and a method...
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7223393 |
Amphiregulin antibodies and their use to treat cancer and psoriasis
The present invention is directed to anti-AR antibodies, preferably humanized monoclonal antibodies having the amino acid sequences disclosed herein. The present invention includes a pharmaceutical...
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7223389 |
Compositions and methods for treatment of cancer
The present invention discloses lentogenic viral strains useful in the treatment of cancer. A preferred viral strain of Newcastle Disease Virus (NDV) is specifically characterized in terms of...
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