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9724350 N,6-bis(aryl or heteroaryl)-1,3,5-triazine-2,4-diamine compounds as IDH2 mutants inhibitors for the treatment of cancer  
Provided are compounds of formula (I), Wherein: ring A and ring B are each independently an optionally substituted 5-6 membered monocyclic aryl or heteroaryl. The compounds are inhibitors of...
9724349 Methods for the treatment of HER2 amplified cancer  
Described herein are methods and compositions for treating HER2-amplified cancer. The methods include administering to an individual in need thereof ibrutinib.
9724337 AG-205 for the treatment of breast cancer  
Compositions, methods, and combination therapies for the treatment of cancers, including lymphomas, leukemias, melanomas, lung cancer, and metastatic disease, are provided. Specifically,...
9724323 Breast cancer therapy based on hormone receptor status with nanoparticles comprising taxane  
The present invention relates to methods and kits for the treatment of breast cancer based on hormone receptor status of progesterone receptor and estrogen receptor comprising the administration...
9719995 Drug selection for colorectal cancer therapy using receptor tyrosine kinase profiling  
The present invention provides methods for selecting a suitable anticancer drug therapy, and for identifying and predicting response, for the treatment of colorectal cancer. The present invention...
9719937 Diagnosis of cancer  
A method is provided including obtaining an infrared (IR) spectrum of a blood plasma sample by analyzing the blood plasma sample by infrared spectroscopy, and based on the infrared spectrum,...
9719093 Composition for treating cancer associated with HPV infection  
The present invention relates to a composition for preventing or treating diseases associated with human papillomavirus (HPV), and more specifically, cancer associated with HPV, and even more...
9718887 Methods and products for preventing and/or treating metastatic cancer  
The present disclosure relates to the prevention and/or treatment of metastatic cancer. Certain example embodiments of the present disclosure provide a method for preventing and/or treating a...
9718886 Cancer therapy using CLDN6 target-directed antibodies in vivo  
The invention relates to the treatment and/or prevention of tumor diseases associated with cells expressing CLDN6, in particular cancer and cancer metastasis using antibodies which bind to CLDN6....
9718866 Colon and pancreas cancer peptidomimetics  
The invention relates to a peptidomimetic of an NPC-1 epitope on the MUC5AC protein which is differentially expressed in pancreatic and colorectal cancer, and diagnostic and therapeutic usages....
9718813 Imidazolin-5-one derivative useful as FASN inhibitors for the treatment of cancer  
The present invention is directed to imidazolin-5-one derivatives, pharmaceutical compositions containing them, and their use as FASN inhibitors, in for example, the treatment of cancer, obesity...
9718809 Bisarylsulfonamides useful in the treatment of inflammation and cancer  
A compound of formula (I), useful for the treatment of cancer, inflammation and inflammatory disorders, and a pharmaceutical composition containing the compound.
9718799 3-aryl-4H-chromene-4-ones as antineoplastic agents for the treatment of cancer  
Isoflavonoids or pharmaceutically acceptable salts thereof or pharmaceutically acceptable compositions thereof for the treatment of prostate cancer or for the treatment or inhibition of prostate...
9717806 Method for detecting cancer using ICG fluorescence method  
A method of detecting an accessory cancer lesion, comprising an administration step wherein indocyanine green is administered to a living body, an irradiation step wherein a target organ suspected...
9717794 Compositions and methods for treating and diagnosing cancer  
The present invention relates to compositions and methods for characterizing, diagnosing and treating cancer. In particular, the present invention identifies LGR5 as a protein over-expressed in...
9717792 Combination therapy for cancer using HSP27 inhibitor and EGFR tyrosine kinase inhibitors or anti-folates  
Combination therapy for cancer makes use of HSP27 inhibitors and EGFR tyrosine kinase inhibitors or etiolates.
9717781 Methods and compositions relating to P62 for the treatment and prophylaxis of cancer  
Provided herein are novel p62 compositions for the prophylaxis and treatment of cancer and related methods. The invention also provides modified p62 compositions that increase the anti-cancer...
9717774 Immunotherapy against several tumors including gastrointestinal and gastric cancer  
The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present...
9717745 Pharmaceutical compositions and their use for treatment of cancer and autoimmune diseases  
Described herein are combination therapies for cancer (such as lymphoid malignancies) and immune diseases (such as autoimmune diseases and inflammatory diseases). The therapies comprise the...
9717724 Methods for treating pancreatic cancer using combination therapies  
Provided are methods for treating pancreatic cancer in a patient by administering liposomal irinotecan (MM-398) alone or in combination with additional therapeutic agents. In one embodiment, the...
9717717 Methods of treating cancer through the inhibition of USP7 and immune system modulation  
Methods and compounds for treating cancer by, for example, modulating immune system activity, are provided.
9717702 Treatment of cancer with specific RXR agonists  
A method of treating cancer is disclosed comprising administering to a patient in need of such treatment a RXR agonist at a level below the RAR activating threshold and at or above the RXR...
9717695 Constructs for diagnosing and treating inflammatory bowel diseases and colon cancer  
The present invention features, inter alia, constructs for the delivery of therapeutic and diagnostic agents to a patient. The constructs can include a nanoparticle, a targeting agent that...
9717686 Combinational liposome compositions for cancer therapy  
The present invention provides methods for delivery of therapeutic agents to a subject using multi-component liposomal systems. The methods include administration of a therapeutic liposome...
9714298 Anti-FGFR2 antibodies and methods of use thereof for treating cancer  
The present invention provides an antibody which binds to a fibroblast growth factor receptor.
9714275 Cancer antigen  
Cancer cells when treated with cisplatin, paclitaxel, gemcitabine, Mycobacterium w or combination there of shows altered protein profile. Thus altered protein profile has at least one protein...
9713625 MicroRNAs useful for treating ovarian cancer  
Described herein are methods for diagnosing ovarian cancer. In particular, certain microRNAs are useful to the response to chemotherapy of ovarian cancer patients.
9713613 Methods and compositions for the treatment of cancer and related hyperproliferative disorders  
The present invention relates to methods of treating a disease related to cell hyper-proliferation via administration of a therapeutically effective amount of a compound having a general...
9713612 Compounds for treatment of cancer  
The present invention relates to compounds as inhibitor of WNT signal transduction pathway, as well as a composition comprising the same. Further, the present invention relates to the use of the...
9713601 Ingenol derivative compounds and methods useful for inhibiting cancer cell viability and treating cancer  
The present invention relates to new ingenol derivative compounds for inhibiting cancer cell viability and treating cancer. In other aspects, the invention relates to a pharmaceutical composition,...
9709556 Devices and methods for determining and/or isolating circulating cancer cells  
The present invention generally relates to devices and methods for determining and/or isolating cells. One aspect is generally directed to methods and devices for detecting, identifying, counting,...
9708612 Methods and compositions using miR-3151 in the diagnosis and treatment of thyroid cancer  
Compositions comprising therapeutic oligonucleotide miR-3151 compounds that target the expression of genes associated with tumorigenesis or cell transformation are provided.
9708283 Isoflavonoid compositions and methods for the treatment of cancer  
Provided herein is a pharmaceutical composition comprising an isoflavonoid derivative and a cyclodextrin. Also provided herein are methods of treating cancer, sensitizing cancer cells, and...
9708279 2-acylaminothiazoles for the treatment of cancer  
The present invention relates to inhibitors of the oncogenic protein kinase ALK of formula (I): as herein described and pharmaceutical compositions thereof. The compounds of formula (I) are useful...
9708276 Small molecules targeting androgen receptor nuclear localization and/or level in prostate cancer  
A method for treating prostate cancer in a subject, comprising administering a therapeutically effective amount of at least one agent to the subject, wherein the agent is selected from: (a) a...
9707302 Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer  
The present invention relates to combination therapy with drugs, such as microtubule inhibitors, PARP inhibitors, Bruton kinase inhibitors or PI3K inhibitors, with antibodies or immunoconjugates...
9707254 Method for prevention and treatment of cancer, tuberculosis and related diseases  
A method for preventing and treating one or more disease states including the steps of altering the diet of an individual and then administering a drug to the individual. Plasma vitamin C level is...
9707248 Use of thiopyrimidinecarboxamide for treating cancer  
There is disclosed is a method of treating cancer using compound having formula SX-682 alone or in combination with an antineoplastic agent, microtubule affecting agents, antineoplastic agents,...
9707221 Methods of treating cancer patients with farnesyltransferase inhibitors  
The present invention relates to the field of molecular biology and cancer biology. Specifically, the present invention relates to methods of treating a subject with a farnesyltransferase...
9707204 Treatment of breast cancer  
The present invention relates to the use of a liposomal preparation for the manufacture of a pharmaceutical composition and the use of such a composition for the treatment of “triple receptor...
9707196 Treatment agent and/or prophylactic agent for side effects of cancer drugs  
A method for treating side effects of anticancer agent includes administering to a subject in need thereof a prophylactic and/or therapeutic agent containing a therapeutically effective amount of...
9702880 Antisense RNA for treating cancer and inhibition of metastasis and vectors for antisense sequestration  
Provided is the use of antisense RNA and methods for the treatment, diagnosis and prophylaxis of cancer comprising administering said antisense RNA, particularly miRs 15 and 16 to a patient in...
9702878 Method for the prognosis and treatment of cancer metastasis  
The present invention relates to a method for the prognosis of bone metastasis in triple negative (including basal-like) breast cancer or, alternatively, ER+ breast cancer (including luminal A and...
9702876 Method for predicting the risk of getting cancer or diagnosing cancer in a female subject  
Subject matter of the present invention is a method for predicting the risk of getting cancer in a female subject that does not suffer from cancer or alternatively diagnosing cancer in a female...
9702875 Expression of isoform 202 of ERCC1 for predicting response to cancer chemotherapy  
An in vitro method for detecting the susceptibility of a tumor cell to a chemotherapy is disclosed. The method includes the step of measuring the expression level of the isoform 202 of the ERCC1...
9702011 Markers for breast cancer  
Correlations between polymorphisms and breast cancer are provided. Methods of diagnosing, prognosing, and treating breast cancer are provided. Systems and kits for diagnosis, prognosis and...
9702010 Therapy with Clostridium perfringens enterotoxin to treat ovarian and uterine cancer  
The invention discloses high levels of receptors for Clostridium perfringens enterotoxin (CPE) have been found in ovarian cancer and uterine cancer tissue samples. In addition, successful in vivo...
9702009 Urine gene expression ratios for detection of cancer  
This invention relates to methods for determining the presence of cancer in a subject based on the analysis of the expression levels of an under-expressed tumor marker (TM) and at least one other...
9701985 mda-9/syntenin promoter to image and treat metastatic cancer cells  
Recombinant vectors in which expression of one or more elements (e.g. gene required for viral replication, detectable imaging agents, therapeutic agents, etc.) is driven by an mda-9/syntenin...
9701755 Membrane transporter NaPi2b (SCL34A2) epitope for antibody therapy, antibodies directed thereto, and target for cancer therapy  
The present invention relates generally to the membrane transporter NaPi2b (SLC34A2) as a target for therapy, including immunotherapy, and particularly cancer therapy. The SLC34A2 epitope peptide...