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9856536 Method for treating castration-resistant prostate cancer  
Methods and kits for characterizing a subject having a steroid-dependent disease such as prostate cancer are described. A method of treating a steroid-dependent disease in a subject by obtaining a...
9856533 Predicting breast cancer treatment outcome  
Methods and compositions are provided for the identification of expression signatures in ER+ breast cancer cases, where the signatures correlate with responsiveness, or lack thereof, to treatment...
9856320 Cancer immunotherapy by disrupting PD-1/PD-L1 signaling  
The disclosure provides a method for immunotherapy of a cancer patient, comprises administering to the patient an Ab that inhibits signaling from the PD-1/PD-L1 signaling pathway, or a combination...
9856291 Cancer stem cell targeting peptide and use thereof  
A synthetic peptide that targets cancer stem cells is provided. The peptide consists of the amino acid sequence of anyone of SEQ ID NO: 1 to SEQ ID NO: 15. Also provided is a composition...
9856260 Compounds useful for inhibiting metastasis from cancer and methods using same  
The present invention includes compositions that are useful in preventing or treating metastasis in a subject diagnosed with cancer. The present invention also includes methods of preventing or...
9856255 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer  
The specification generally relates to compounds of Formula (I): and pharmaceutically acceptable salts thereof, where R1, R2, R3, R4 and R5 have any of the meanings defined herein. The...
9855349 Selectin ligands useful in the diagnosis and treatment of cancer  
The present invention provides methods and compositions useful in the diagnosis and treatment of cancer. More specifically, the present invention provides compositions and methods of use...
9855348 Radio-labelled antibody fragments for use in the prevention and/or treatment of cancer  
The application provides polypeptides comprising or essentially consisting of at least one heavy chain variable domain of a heavy chain antibody (VHH) or functional fragments thereof, wherein said...
9855347 Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells  
The invention relates to methods for producing papilloma-derived nanosphere particles that contain therapeutic, diagnostic, or other agents. The invention also provides nanosphere particle...
9855342 Targeting ABCB5 for cancer therapy  
The invention relates to methods for treating a subject by manipulating ABCB5 on a cell as well as related products. The methods include methods of treating cancer using ABCB5 binding molecules...
9855316 Granulocyte-macrophage colony stimulating factor for enhancing pulmonary host defense in acute and chronic radiation syndrome, therapeutic radiation intervention and cancer therapy  
Methods and compositions for treating and alleviating symptoms of irradiation injuries, therapeutic radiation intervention and/or anti-cancer therapies in a subject via pulmonary airway...
9855302 Treatment of cancer by manipulation of commensal microflora  
Provided herein are methods of treatment and/or prevention of cancer by manipulation of commensal microflora. In particular, the amount, identity, presence, and/or ratio of microflora (e.g., gut...
9855265 Methods for treating cancer with TrkA receptor tyrosine kinase antagonists  
The present disclosure relates to novel synthetic substituted heterocyclic compounds and pharmaceutical compositions containing the same, said compounds being capable of inhibiting or antagonizing...
9855261 Polymeric compound having camptothecin compound and anti-cancer effect enhancer bound thereto, and use of same  
The purpose of the present invention is to provide a polymeric compound in which a camptothecin compound and an anti-cancer effect enhancer, particularly a PARP inhibitor, are bound to a single...
9855255 Substituted naphthyridinyl hydrazines as anti-liver cancer agents  
The substituted naphthyridinyl hydrazine compounds as anti-liver cancer agents are anti-liver cancer agents that inhibit proliferative pathways of cancer cells, thereby exhibiting potent in vitro...
9855250 Method to treat lung cancer  
One example embodiment relates to a method of treating lung cancer by administering a compound of formula I to a subject in need thereof. Another embodiment relates to a method to treat Non-Small...
9855220 Methods of treating pancreatic cancer  
Provided herein are methods for the treatment of metastatic pancreatic cancer comprising administration of a composition comprising nanoparticles comprising a taxane (such as paclitaxel) and a...
9855216 Targeted nano-liposome co-entrapping anti-cancer drugs  
A liposomal composition includes at least two anti-tumor herbal drugs that are simultaneously co-encapsulated. Optionally, the liposomal composition is targeted by adding a monoclonal antibody is...
9851421 Differential atlas for cancer assessment  
Methods and apparatus associated with producing a quantification of differences associated with biochemical recurrence (BcR) in a region of tissue demonstrating prostate cancer (PCa) are...
9851363 Method for monitoring cancer and/or inflammatory reaction based on RelB phosphorylation  
The present Inventors demonstrated that the RelB subunit of NFκB plays a crucial role in promoting cell migration. More precisely, they identified that this pro-migratory activity is mediated by...
9851357 Method for the prognosis of survival time of a patient suffering from a solid cancer  
The present invention relates to an in vitro method for the prognosis of survival of a patient suffering from a solid cancer, comprising the quantification of the cell density of CD8+ cells and...
9850544 Genetic amplification of IQGAP1 in cancer  
We examined IQGAP1 copy gain and its relationship with clinicopathologic outcomes of thyroid cancer and investigated its role in cell invasion and molecules involved in the process. We found...
9850542 Gene signature to predict homologous recombination (HR) deficient cancer  
Methods for identifying and treating cancers that are homologous recombination (HR)-repair defective. In some aspects, HR defective cancers are treated with a PARP inhibitor therapy. Methods for...
9850541 Methods and kits for detecting subjects at risk of having cancer  
The present invention relates to agents and methods for screening, diagnosis and surveillance of cancer, in particular pancreatic cancer.
9850540 Method for detecting lung cancer using lung cancer-specific methylation marker gene  
The present invention relates to a method for detecting lung cancer using a lung cancer-specific biomarker, and more particularly to a biomarker for lung cancer diagnosis, which can detect...
9850313 Cancer biomarkers and methods of use thereof  
Methods and compositions for treating cancer, particularly breast cancer, are disclosed.
9850311 Compositions and methods for diagnosing and treating cancer  
An isolated antibody that specifically binds to an extracellular domain of two or more human FZD receptors and inhibits growth of tumor cells is described. Also described is a method of treating...
9850300 Compositions and methods relating to inhibiting cancer cell growth and/or proliferation  
The present invention determined that EGFL6 functions as a tumor vascular regulator of ovarian cancer stem cells (CSC). In addition, the present invention determined that a novel EGFL6 blocking...
9850293 Targeting trastuzumab-resistant HER2+ breast cancer with a HER3-targeting nanoparticle  
Disclosed herein are methods of treating cancer in a patient, the method comprising identifying a patient who is resistant to treatment with an anti-HER2 therapy; and administering to the patient...
9850273 Combination of estrogens plus antiprogestins with significant partial agonistic effect as an effective treatment of menopausal symptoms and for prevention of the occurrence of breast cancer  
Described herein are compositions and methods for hormone replacement therapy that address the shortcomings of the existing methods. Described herein are pharmaceutically effective partial...
9850221 Sulfated and unsulfated flavonoid oligomers as cancer therapeutics  
Sulfated and unsulfated flavonoid oligomers as inhibitors of cancer stem cells (CSCs) are provided. In particular, sulfated flavonoid dimers are shown to selectively inhibit CSCs growth and...
9849190 Peptide having cancer selective translocation function and use thereof  
A method of treating breast cancer is described, in which a peptide having cancer selective translocation function-doxoribicin conjugate is administered. The conjugate includes doxorubicin...
9849160 Methods and systems for treating or preventing cancer  
The present invention generally relates to compositions and methods for treatment of subjects having or at risk of cancer or other conditions. In some cases, the composition may include nitric...
9849127 Means and methods for treating cancer  
The present invention relates to a pharmaceutical composition comprising a compound of formula (I) and methods of treating or preventing cell proliferation disorders comprising administering to a...
9849103 Compositions and methods for the treatment of cancer  
The present invention discloses anti-cancer compositions, and associated methods, including an anti-cancer composition comprising: a cellular energy inhibitor having the structure according to...
9849092 Early cancer detection and enhanced immunotherapy  
A method of therapy for a tumor or other pathology by administering a combination of thermotherapy and immunotherapy optionally combined with gene delivery. The combination therapy beneficially...
9848598 Cryoprotected, frozen recombinant cancer cells  
This invention provides compositions and methods for cryoprotection of recombinant live cancer cells. Specifically, an improved cryoprotective medium is provided which includes a hydroxyethyl...
9846162 Immune biomarkers and assays predictive of clinical response to immunotherapy for cancer  
The present invention relates to predictors of a cancer patient's responsiveness to immunotherapy for cancer.
9846160 Ganglioside GD2 as a marker and target on cancer stem cells  
Methods for determining the presence of cancer stem cells by detecting GD2 expression. Also provided are methods for reducing proliferation of cancer stem cells by contacting the cells with a GD2...
9846159 BIN1 expression as a marker of cancer  
Provided are methods for screening a subject for cancer. The methods involve obtaining a blood sample from the subject and determining a level of Bridging Integrator 1 (BIN1) isoforms comprising...
9846158 Predictive biomarkers for ovarian cancer  
Methods are provided for predicting the presence, subtype and stage of ovarian cancer, as well as for assessing the therapeutic efficacy of a cancer treatment and determining whether a subject...
9845506 Method for determining prognosis of prostate cancer in a subject  
A method for determining the prognosis of prostate cancer in a subject is provided which comprises the assessment of the methylation status of the HSPB1 gene in a prostate cancer sample.
9845472 Methods of using PVT1 exon 9 to diagnose and treat prostate cancer  
PVT1 exon 9 is overexpressed in aggressively tumorigenic prostate cancer cell lines and prostate tumor tissues. This exon provides a diagnostic tool for the detection and monitoring of aggressive...
9845471 Compositions and methods for treating pancreatic cancer  
The present disclosure provides compositions and methods for treating or reducing the risk of pancreatic cancer by administering compounds capable of inhibiting the expression or activity of RUNX3.
9845470 Targeting microRNAS for the treatment of liver cancer  
Provided herein are methods for the treatment of liver cancer. These methods encompass the administration of a compound comprising a modified oligonucleotide, wherein the modified oligonucleotide...
9845364 Anti-ADAM28 antibody for treating cancer  
The present invention provides an antibody that specifically binds to human ADAM28, inhibits enzyme activity of human ADAM28, and has an activity to suppress metastasis of a cancer cell that...
9845283 Methods of producing cancer targeting compounds  
Provided herein are methods of making the compound of Formula I: and certain intermediates involved in such process.
9844595 Composition comprising a complex of (+)-catechin and amino acid for the treatment and prevention of cancer  
The invention relates to a gastroenteric therapeutic composition for oral administration, comprising a compound of monomeric (+)-catechin and at least one basic amino acid, said composition being...
9844574 Cancer treatment using viruses and camptothecins  
Mammalian subjects having a neoplasm are treated with a virus and a camptothecin compound, for example irinotecan or topotecan. The virus is selected from the group consisting of a Newcastle...
9844547 Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases  
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed...