|
Match
|
Document |
Document Title |
|
|
7279307 |
Metastatic breast and colon cancer regulated genes
Gene sequences as shown in SEQ ID NO:1-18 have been discovered and isolated, and found to be significantly associated with metastatic spread of breast and colon cancer cells to other organs....
|
|
|
7279294 |
Tumor markers in ovarian cancer
The present invention features methods of diagnosing and prognosticating ovarian tumors by detecting increased expression of an ovarian tumor marker gene in a subject or in a sample from a subject....
|
|
|
7274809 |
Computerized methods and systems related to the detection of malignancy-associated changes (MAC) to detect cancer
Computer programs, systems and the like related to processing, segmenting and feature normalizing digital images. The images are of cells and the methods are useful for the detection of...
|
|
|
7273855 |
Use of prohibitin RNA in treatment of cancer
It has now been found that the introduction of single stranded oligonucleotides of DNA or RNA, particularly RNA transcribed from portions of wild type prohibitin 3′UTR, into tumors leads to...
|
|
|
7273852 |
Synthetic C-glycolipid and its use for treating cancer, infectious diseases and autoimmune diseases
The invention is directed to compounds of formula (I)
wherein X is O or NH; R′ is a hydrocarbon chain; R 3 and R 4 are hydrogen, OH or a monosaccharide; R 5 is hydrogen or a...
|
|
|
7273625 |
Minari extract for preventing the induction and metastasis of cancer by carcinogens contained in cigarette smoke, fermented foods or alcoholic drinks
An extract of the Minari plant containing a component which prevents cancer and cancer metastasis. A Minari extract which is useful for the prevention of cancer and cancer metastasis induced by...
|
|
|
7271240 |
125P5C8: a tissue specific protein highly expressed in various cancers
A novel gene (designated 125P5C8) and its encoded protein are described. While 125P5C8 exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed multiple cancers...
|
|
|
7270980 |
Compounds for immunodiagnosis of prostate cancer and methods for their use
Compounds and methods for diagnosing prostate cancer are provided. The inventive compounds include polypeptides containing at least a portion of a prostate tumor protein. The inventive polypeptides...
|
|
|
7270812 |
Pharmaceutical composition for treatment of cancers
The present invention relates to a pharmaceutical composition for treatment of cancers containing Sindbis virus as an active ingredient, a method for treatment of cancers, which comprises...
|
|
|
7268207 |
Gene differentially expressed in breast and bladder cancer, and encoded polypeptides
The present invention relates to a novel human gene that is differentially expressed in human carcinoma. More specifically, the present invention relates to a polynucleotide encoding a novel human...
|
|
|
7268120 |
Methods for treating cancer using cytokine-expressing polynucleotides
The present invention provides a pharmaceutical composition, comprising a non-infectious, non-integrating polynucleotide construct comprising a polynucleotide encoding an interferon ω and one or...
|
|
|
7267977 |
Peripheral-type benzodiazepine receptor: a tool for detection, diagnosis, prognosis, and treatment of cancer
The expression and subcellular localization of peripheral-type benzodiazepine receptors (PBR) is shown in this application to correlate with the metastatic potential of cells, and increased cell...
|
|
|
7267961 |
Peptides from the E7 protein of human papilloma viruses 16 and 18 for detecting and/or diagnosing cervical and other human papilloma virus associated cancers
An isolated protein sequence or peptide from the E2, E6 or E7 early coding region of human papillomavirus (HPV) that is soluble in an aqueous medium, and characterized by a relative paucity of...
|
|
|
7267956 |
Nucleic acid sequences for detecting genetic markers for cancer in a biological sample
Nucleic acid sequences for detecting the presence of nucleic acids, particularly mRNA, encoding human prostate-associated genetic markers encoding prostate-specific antigen (PSA), prostate specific...
|
|
|
7267821 |
Binding member which binds to both Lewisy and Lewisb haptens, and its use for treating cancer
The invention relates to the use of a binding member which binds to Lewis y and Lewis b haptens in the treatment of tumours and leukaemia. The binding member may be an antibody which binds to...
|
|
|
7264928 |
Method for the prediction of the risk potential for cancerous diseases and inflammatory intestinal diseases and corresponding tests
The invention relates to a method for the prediction of the risk potential and/or diagnosis of cancerous diseases or inflammatory intestinal diseases, whereby a DNA sample is tested for the...
|
|
|
7264820 |
Cancer immunotherapy using autologous tumor cells combined with cells expressing a membrane cytokline
This invention comprises cellular vaccines and methods of using them in cancer immunotherapy, particularly in humans. The vaccines comprise a source of tumor-associated antigen, and a...
|
|
|
7264814 |
Composition and method for treating cancer using herpes virus
The present invention provides a herpes virus in which a non-essential gene for replication is inactivated More particularly, the present invention provides a herpes virus in which a non-essential...
|
|
|
7264800 |
Method and composition for inhibiting cancer cell growth
Improvements in methods of treating cancer with weakly basic anti-cancer compounds are provided. In one aspect, the invention provides an improvement in a method of treating cancer cells whose...
|
|
|
7262276 |
Anti human ovarian cancer-anti CD3 bispecific antibody
The present invention provides an anti-ovarian cancer bispecific antibody. Said antibody includes two polypeptide domains connected by a polypeptide linker, one is anti-ovarian cancer antibody, or...
|
|
|
7262269 |
Method for screening combinational bead library; ligands for cancer cells
The invention includes a cell-growth-on-bead assay for screening a one-bead-one-compound combinatorial bead library to identify synthetic ligands for cell attachment and growth or proliferation of...
|
|
|
7262213 |
Compounds and methods for the treatment of cancer
(−)-(2S,4S)-1-(2-Hydroxymethyl-1,3-dioxolan-4-yl)cytosine (also referred to as (−)-OddC) or its derivative and its use to treat cancer in animals, including humans.
|
|
|
7262202 |
Inhibitors of cyclin dependent kinases as anti-cancer agent
The present invention relates to 2-substituted 4-heteroaryl-pyrimidines, their preparation, pharmaceutical compositions containing them and their use as inhibitors of cyclin-dependent kinases...
|
|
|
7261906 |
Anti-cancer therapy agent of arsenic hexoxide (As4O6) of a natural chemical substance and its pharmaceutical composition
A process for preparing As 4 O 6 comprises successively heating and cooling a mixture of natural Sinsuk and 40% alcohol in a ratio of about 1: about 1 for about 1 to about 2 hour(s) resulting in a...
|
|
|
7261892 |
Methods for diagnosis and treatment of epithelial-derived cancers
The present invention relates to the use of a polypeptide (CD27L) for diagnosis of epithelial-related cancers, in particular kidney cancer e.g. renal cell cancer and colorectal cancer, e.g. colon...
|
|
|
7259188 |
Methods and pharmaceutical compositions for treatment of anti-estrogen resistant breast cancer using RXR modulators
Methods and compositions for the treatment of anti-estrogen resistant breast cancer using retinoid compounds which are modulators of Retinoid X Receptors.
|
|
|
7258991 |
Antibody to bladder cancer nuclear matrix protein and its use
Nuclear matrix proteins (NMP) which are characterized by a defined expression in tissue are provided. These NMPs are useful markers in diagnosing and monitoring the stage of malignancy of a cell...
|
|
|
7258860 |
Compositions and methods for the therapy and diagnosis of lung cancer
Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic...
|
|
|
7257437 |
Autofluorescence detection and imaging of bladder cancer realized through a cystoscope
Near infrared imaging using elastic light scattering and tissue autofluorescence and utilizing interior examination techniques and equipment are explored for medical applications. The approach...
|
|
|
7256272 |
Individualized anti-cancer antibodies
The present invention relates to a method for producing patient specific anti-cancer antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell...
|
|
|
7256271 |
Cancerous disease modifying antibodies
The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer...
|
|
|
7256037 |
Modified vaccinia Ankara expressing p53 in cancer immunotherapy
Mutations to the tumor suppressor protein p53 have been observed in 40-60% of all human cancers. These mutations are often associated with high nuclear and cytoplasmic concentrations of p53. Since...
|
|
|
7253209 |
Remedies for cisplatin-tolerant cancer
Preparation of a lipophilic platinum complex being dissolved or suspended in an iodized poppyseed oil fatty acid ethyl ester is useful as an agent for treatment of cisplatin-resistant cancers.
|
|
|
7252976 |
Quantitative RT-PCR to AC133 to diagnose cancer and monitor angiogenic activity in a cell sample
The present invention involves the use of quantitative RT-PCR to identify AC133 as a marker. AC133 is prevalent on endothelial progenitor cells (EPCs), which are important cells in angiogenesis....
|
|
|
7252955 |
Method of detecting colon cancer
An immunological assay and kit for colon cancer screening is disclosed. Fecal glycoproteins are extracted from individual samples such that immunogenicity is maintained. The purified fecal...
|
|
|
7252935 |
Method of detection of prostate cancer
The present invention provides methods and kits useful for detecting neplasia by measuring the methylation level of biomarkers, especially the promoter region of GSTP1 for the detection of prostate...
|
|
|
7252824 |
Anti-neovasculature preparations for cancer
Disclosed herein are immunogenic compositions, methods of designing immunogenic compositions, methods of treatment using immunogenic compositions, methods of evaluating cell-mediated immunity...
|
|
|
7252821 |
Cancerous disease modifying antibodies
The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer...
|
|
|
7250498 |
Nucleic acids and corresponding proteins entitled 273P4B7 useful in treatment and detection of cancer
A novel gene 273P4B7 and its encoded protein, and variants thereof, are described wherein 273P4B7 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the...
|
|
|
7250492 |
Compositions and methods for inhibition of cancer invasion and angiogenesis
The invention provides antibodies that specifically bind a membrane protease complex, the complex consisting of two homodimers of seprase and dipeptidyl peptidase IV (DPPIV), obtained from...
|
|
|
7250438 |
Anti-bacterial and anti-cancer spiro beta-lactone/gamma-lactams
Disclosed herein are novel spiro beta-lactone/gamma lactams for use in treating bacterial infections and cancer. The compounds are characterized by a terminal electron-withdrawing group such as a...
|
|
|
7250435 |
Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents
The present invention relates to the synthesis of a new class of indeno[1,2-c]pyrazol-4-ones of formula (I):
that are potent inhibitors of the class of enzymes known as cyclin dependent...
|
|
|
7250432 |
Pharmaceutical compositions of diaryl-isoxazole derivatives for the prevention and treatment of cancers
The present invention relates to a pharmaceutical composition for the prevention and the treatment of cancers containing diaryl-isoxazole derivatives as an effective ingredient. Diaryl-isoxazole...
|
|
|
7250423 |
Methods for synthesizing heterocycles and therapeutic use of the heterocycles for cancers
The present invention provides methods for synthesizing novel tetrahydroquinoline derivatives that are useful for cancer chemotherapy and anti-viral applications. The present invention provides...
|
|
|
7250180 |
Anti-prostate cancer composition and therapeutic uses therefor
Disclosed are methods and compositions useful in treating prostate cancer. The invention is based on BIRM, an extract of the plant Solanaceae - Dulcamara and its previously unrecognized...
|
|
|
7247734 |
3,4-diarylpyrazoles and their use in the therapy of cancer
The present invention pertains to the use of certain 3,4-diarylpyazoles of formula (I), both in vitro and in vivo, to inhibit heat shock protein 90 (HSP90), and in the treatment of conditions...
|
|
|
7247715 |
Ricin-like toxin variants for treatment of cancer, viral or parasitic infections
The present invention provides a protein having an A chain of a ricin-like toxin, a B chain of a ricin-like toxin and a heterologous linker amino acid sequence, linking the A and B chains. The...
|
|
|
7247610 |
Use of glutamate antagonists for the treatment of cancer
Disclosed are methods for treating cancer by administering an inhibitor of the interaction of glutamate with the KA receptor complex.
|
|
|
7247476 |
Individualized anti-cancer antibodies
The present invention relates to a method for producing patient specific anti-cancer antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell...
|
|
|
7247444 |
Use of interleukin-19 to treat cervical cancer
The present invention relates to the anti-cancer activity of IL-19 polypeptide molecules. IL-19 is a cytokine involved in inflammatory processes and human disease. The present invention includes...
|