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9745348 Short designed peptides possessing selective actions against bacteria and cancer cells  
The present invention relates to amphiphilic peptides having antibacterial and/or antitumor activity, and to therapeutic and non-therapeutic compositions comprising these peptides. The peptides...
9745288 Compounds and methods for treating cancer by inhibiting the urokinase receptor  
Compounds and methods for treating or preventing cancer associated with binding to the urokinase receptor are provided. Biological processes affected by the compounds include cell migration, cell...
9745278 Group of STAT3 pathway inhibitors and cancer stem cell pathway inhibitors  
The present invention relates to the use of a novel class of cancer stem cell pathway (CSCP) inhibitors; to methods of using such compounds to treat refractory, recurrent, or metastatic cancers;...
9744380 Patient specific beam control assembly of a cancer therapy apparatus and method of use thereof  
The invention comprises a patient specific tray insert removably inserted into a tray frame to form a beam control tray assembly, which is removably inserted into a slot of a tray receiver...
9744224 Methods for treating cancer by administration of nucleic acids encoding FAP and cancer antigens  
A immunogenic composition is provided for use in methods for treating or preventing the development of a cancer, comprising a nucleic acid sequence encoding a cancer antigen and a nucleic acid...
9744223 Therapeutic cancer vaccine targeted to HAAH (aspartyl-[asparaginyl]-β-hydroxylase)  
The present invention encompasses a cancer vaccine therapy targeting Aspartyl-[Asparaginyl]-β-hydroxylase (HAAH). The present invention contemplate bacteriophage expressing HAAH peptide fragments...
9744212 Galectin-3C combination therapy for human cancer  
The present invention provides a novel composition of matter useful for the treatment of neoplastic diseases. The novel composition is synergistic and comprised of galectin-3C in combination with...
9744206 Pharmaceutical compositions for treating cancer of genital system and preparation method therefor  
A pharmaceutical composition for preventing and treating cancer of reproductive system and preparation method therefor. The pharmaceutical composition is prepared using one or more of the...
9744205 Alcohol extract of dehulled adlay seeds for treating breast cancer  
The present invention provides a method for treating breast cancer in a subject, which comprises administering to said subject an effective amount of an alcohol extract of dehulled adlay seeds....
9744175 Compositions of combinations of non-covalent DNA binding agents and anti-cancer and/or anti-inflammatory agents and their use in disease treatment  
The invention provides for compositions for treating a cancer or an inflammatory disorder comprising a combination of agents in a pharmaceutically acceptable carrier, wherein said agents comprise:...
9744172 Pyrazolopyrimidine compounds for the treatment of cancer  
Compound of Formula I: are described, along with pharmaceutically acceptable salts thereof, compositions containing the same, and methods of use thereof in the treatment of cancer.
9744145 Methods for treating lung cancer  
This invention provides a method of treating lung cancer including administering a therapeutically effective amount of a compound of 0089-0022 formula I to a subject in need thereof. The compound...
9743836 Excitation, detection, and projection system for visualizing target cancer tissue  
A system visually distinguishes diseased tissue from healthy tissue after a treatment is administered to a patient to provide different concentrations of a fluorescent marking substance between...
9739784 Giant obscurins and uses thereof in cancer prognosis and therapy  
Provided herein are methods and kits for evaluating potential for invasiveness, metastasis, or recurrence of an epithelial cell cancer. In the methods the expression profile of giant obscurins is...
9739783 Convolutional neural networks for cancer diagnosis  
The present disclosure provides devices and systems for diagnosing and characterizing cancer in a subject. Devices include microfilters and microfiltration systems useful for the isolation and...
9739782 Methods and compositions for single chain variable region ENOX2 antibodies for cancer detection and diagnosis  
Cancers of different cellular or tissue origins express different ENOX2 cancer isoforms or combinations of isoforms and shed these proteins into the circulation. Herein are disclosed methods both...
9739780 Metabolite biomarkers for the detection of liver cancer  
Methods for the detection and screening of hepatocellular carcinoma (HCC) patients and for the monitoring of HCC treatment using a panel or panels of small molecule metabolite biomarkers are...
9738936 Breast cancer susceptibility gene GT198 and uses thereof  
It has been discovered that the human GT198 gene (gene symbol PSMC3IP) at chromosome 17q21 acts as a tumor suppressor. The mutation of the GT198 gene causes the increased dominant negative splice...
9737596 Vaccine for the prevention of breast cancer recurrence  
Provided are methods to induce and maintain a protective cytotoxic T-lymphocyte response to a peptide of the HER2/neu oncogene, GP2, with the effect of inducing and maintaining protective or...
9737540 Combination treatment of cancer  
The present invention relates to a combination comprising AZD5363, or a pharmaceutically acceptable salt thereof, and at least one androgen receptor signalling modulator selected from MDV-3100...
9737535 Methods for treating cancer using TOR kinase inhibitor combination therapy comprising administering substituted pyrazino[2,3-b]pyrazines  
Provided herein are methods for treating or preventing a cancer, comprising administering an effective amount of a TOR kinase inhibitor and an effective amount a second active agent to a patient...
9737488 Pharmaceutical composition for the treatment of cancer  
The present invention pertains to a pharmaceutical composition comprising the compound of the formula (I) in a high concentration and at least one pharmaceutically acceptable excipient, the use of...
9737272 Charged particle cancer therapy beam state determination apparatus and method of use thereof  
The invention comprises an apparatus and method of use thereof for determining a charged particle beam state after passage through a final beam modification insert and prior to entering a patient,...
9733187 Method of detecting bladder cancer by optical analysis of bodily fluids  
The method of detecting bladder cancer by optical analysis of bodily fluids utilizes optical techniques to determine a concentration of porphyrin in a patient's bodily fluid sample. The patient is...
9732389 Methods and compositions for correlating genetic markers with prostate cancer risk  
The present invention provides methods of assessing an individual subject's risk of developing prostate cancer, comprising: a) analyzing a nucleic acid sample obtained from the subject and...
9732139 Methods of treating cancer by administering a soluble receptor comprising a human Fc domain and the Fri domain from human frizzled receptor  
The present invention relates to compositions and methods for characterizing, diagnosing, and treating cancer. In particular the invention provides the means and methods for the diagnosis,...
9732131 Identification and use of novopeptides for the treatment of cancer  
Compositions, methods, systems, apparatus and/or articles of manufacture are disclosed for reducing the susceptibility of a population and/or members thereof to cancer, which may include...
9732114 Compounds having anti-adhesive effects on cancer cells  
Compounds of the form O-(x-L)n, where O is an oligonucleoside having at least a plurality of N3′→P5′ thiophosphoramidate (NPS) internucleoside linkages, a conjugated lipid moiety L, and at least...
9732055 Compositions and methods for cancer treatment  
The present invention relates to the composition and methods of use of Stat3 pathway inhibitors or cancer stem cell inhibitors in combination treatment of cancer.
9731023 Somatostatin receptor-based cancer therapy  
Methods and composition for cell-based therapy as well as somatostatin receptor-based therapy are described. For example, in certain aspects methods for administering an anti-tumor therapy using a...
9731022 Pharmaceutical composition comprising amide derivative inhibiting the growth of cancer cells and non-metallic salt lubricant  
Disclosed is a pharmaceutical composition comprising an amide derivative or a pharmaceutically acceptable salt thereof and a non-metallic salt lubricant, which can be used as an effective cancer...
9730967 Method and system for treating cancer cachexia  
Various embodiments of the present invention are directed to the field of Oncology, and in particular embodiments directed to a method of ameliorating, treating, or preventing a malignancy in a...
9730935 Targeting a non-canonical notch signaling pathway for cancer treatment  
Methods and compositions are provided for treating an individual having cancer. Aspects of the methods include administering to the individual an inhibitor of a non-canonical Notch signaling...
9730925 Methods of treating cancer  
This invention relates to methods of treating cancer in a subject such as a human and determining at least one of the following in a sample from the subject, such as a human: (a) the presence or...
9730909 Methods for targeting cancer stem cells  
The invention provides naphthofuran compounds, polymorphs of naphthofuran compounds, naphthofuran compounds in particle form, purified compositions that contain one or more naphthofuran compounds,...
9726676 Means and methods for the prediction of treatment response of a cancer patient  
The present invention relates to the field of treatment efficacy prediction in patients with malignant diseases. More precisely, this invention relates to the prediction of the efficacy of a...
9726670 Method for the assay of liver fatty acid binding protein, ACE and CA 19-9 for the in vitro diagnosis of colorectal cancer  
A method for the in vitro diagnosis of colorectal cancer by determining the presence of Liver Fatty Acid-Binding Protein, ACE and CA19-9 tumor markers in a biological sample taken from a patient...
9726669 Biomarkers for determining sensitivity of breast cancer cells to HER2-targeted therapy  
The present invention provides compositions and methods for detecting the expression and/or activation states of components of signal transduction pathways in cells such as tumor cells....
9726661 Simultaneous detection of cannibalism and senescence as prognostic marker for cancer  
The present inventors show that cannibal cells can undergo senescence after entosis in vivo and that the tumor suppressive protein p53 act as a repressor of this phenomenon. They therefore propose...
9725769 Methods for predicting drug responsiveness in cancer patients  
The present invention features methods, devices, and kits for detecting expression in a patient having cancer or determining responsive of a patient having cancer to a treatment, such as...
9725475 Arsenoplatin anti-cancer agents  
Disclosed herein are conjugates that include a ligand, and a compound having the structure of formula (I) M is Pt, Pd or Ni; Q is As, Sb or Bi; Z1 is N; Z2 is O or S; L1 and L2 are independently...
9725471 Method to prevent cancer metastasis to bone  
A method for treating osteoporosis and related methods are disclosed. The methods generally comprise administering to a patient in need of treatment an effective amount of...
9725447 1-(5-tert-butyl-2-aryl-pyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea derivatives as RAF inhibitors for the treatment of cancer  
The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain...
9725444 Compositions of kinase inhibitors and their use for treatment of cancer and other diseases related to kinases  
Compounds as inhibitors of CSCPK and related kinases. The compounds are thiazole-substituted indolin-2-ones and are prepared from indolin-2-ones. They are included in pharmaceutical compositions...
9725425 Compounds and methods for treating cancer  
Provided are small molecule inhibitors of ubiquitin specific protease 2, 8 and 12 (USP2 and USP8 and USP12) activity and methods for their use in treating cancers. The small molecule inhibitors of...
9724489 Self-referencing optical measurement for breast cancer detection  
Optical data is obtained from a pair of breasts, employing a simultaneous bilateral referencing protocol, and is subsequently analyzed employing a self-referencing data analysis method. Optical...
9724413 Methods of treating cancer using PD-1 axis binding antagonists and MEK inhibitors  
The present invention describes combination treatment comprising a PD-1 axis binding antagonist and a MEK inhibitor and methods for use thereof, including methods of treating conditions where...
9724403 Therapeutic agent for cancer  
The present invention provides an adjuvant for cancer antigen peptide vaccines and virus antigen peptides, containing a pertussis vaccine as a primary ingredient. The present invention also...
9724395 Treatment of cancer with immune stimulators  
The present invention provides compositions and methods for treating cancer or a metastasis thereof in a subject. In some embodiments, the methods involve administering a composition comprising...
9724366 CD11 B[low] macrophages and conditioned media thereof for treating cancer and/or fibrosis  
A conditioned medium of CD11blow macrophages and methods for preparing it are provided. Pharmaceutical compositions comprising the CD11blow macrophages conditioned medium or a culture of CD11blow...