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10143419 Systems and methods for treating cancer and/or augmenting organ function  
Systems, methods and devices for controlled sympathectomy procedures for neuromodulation in the treatment of subjects having neoplastic conditions are disclosed. Systems, methods, and devices for...
RE47141 Methods of treating fibrosis, cancer and vascular injuries  
This invention relates to use of inhibitors of the transforming growth factor-β (TGF-β) type I receptor (ALK5) and/or the activin type I receptor (ALK4) in treating, preventing, or reducing...
10141933 Self-repairing digital device with real-time circuit switching inspired by attractor-conversion characteristics of a cancer cell  
An electric device, which includes a first switch-unit providing a first internal circuit signal, a first delay circuit unit outputting a second internal circuit signal which is generated by...
10139413 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Means and methods for diagnosing pancreatic cancer in a subject based on a metabolite panel
 
The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing pancreas cancer in a subject and, preferably for...
10139412 Semaphorin 3A as a diagnostic marker for urothelial cancer  
The present invention is directed to methods and kits useful for diagnosis and/or prognosis of urothelial cancer in a subject. The present invention further relates to methods of assessing...
10139394 Method for controlling cancer metastasis or cancer cell migration by modulating the cellular level of lysyl tRNA synthetase  
The present invention relates to a novel function of lysyl tRNA synthetase, that is, lysyl tRNA synthetase interacts with 67LR through translocation of KRS into plasma membrane, and so enhances...
10139349 Diagnosis of cancer  
A method is provided including obtaining an infrared (IR) spectrum of a blood plasma sample by analyzing the blood plasma sample by infrared spectroscopy, and based on the infrared spectrum,...
10138523 Cancer biomarker and diagnostic  
The application discloses new biomarkers and methods useful in the diagnosis, prognosis and/or monitoring of, or as a therapeutic or research target for, solid tumor cancers, such as colorectal...
10138488 Cancer vaccine for dogs  
The present invention provides an immunogenic composition comprising a nucleic acid that comprises a sequence encoding a dog telomerase deprived of telomerase catalytic activity, or a fragment...
10138481 miRNAs useful for identifying targets associated with cancer  
Several miRNAs are described that are useful in diagnosing and treating prostate cancer, or pancreatic cancer. The miRNAs bind with targets that are associated with prostate cancer or pancreatic...
10138479 Targeting the glutamine to pyruvate pathway for treatment of oncogenic Kras-associated cancer  
Methods and kits for GPP-targeting, e.g., for the treatment of oncogenic Kras-associated cancers, and methods for determining the efficacy of those methods are provided.
10138299 Cancer immunotherapy by disrupting PD-1/PD-L1 signaling  
The disclosure provides a method for immunotherapy of a subject afflicted with cancer, comprises administering to the subject a composition comprising a therapeutically effective amount of an...
10138287 Uterine cancer treatments  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10138216 Highly selective anti-cancer agents targeting non-small cell lung cancer and other forms of cancer  
Described herein are analogues of 2-methyl-3-(2-ethynylthiazol-4-yl)cyclopent-2-enol and the corresponding ketone 3-(2-ethynylthiazol-4-yl)-2-methylcyclopent-2-enone, the analogues having terminal...
10137204 Anti-DLL3 antibody drug conjugates for treating cancer  
Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
10137203 HER2 aptamer-anticancer drug complex for cancer cell chemotherapy  
A method of manufacturing a complex for cancer cell chemotherapy comprises an aptamer preparation step of preparing a nucleic acid aptamer having an aptamer base sequence specifically binding to...
10137195 Therapy involving antibodies against Claudin 18.2 for treatment of cancer  
The present invention generally provides a therapy for effectively treating and/or preventing diseases associated with cells expressing CLDN18.2, in particular cancer diseases such as...
10137182 Cancer vaccines and vaccination methods  
Compositions of multipeptide vaccines comprising at least seven tumor associated antigens, compositions of antigen presenting cell (e.g., dendritic cell) based vaccines presenting epitopes from at...
10137149 Particles for the treatment of cancer in combination with radiotherapy  
The invention provides a particle comprising a metal oxide which is doped with at least one rare earth element, wherein the metal oxide is selected from titanium dioxide, zinc oxide, cerium oxide...
10137125 Benzenesulfonamide derivatives of quinoxaline, pharmaceutical compositions thereof, and their use in methods for treating cancer  
Benzenesulfonamide derivatives of quinoxaline that are kinase inhibitors, pharmaceutical compositions and methods of using these derivatives, e.g., for treatment of cancer are described.
10137121 Methods of treating cancer with farnesyltransferase inhibitors  
The present invention relates to the field of cancer therapy. Specifically, provided are methods of treating cancer, for example, peripheral T-cell lymphoma (“PTCL”), with a farnesyltransferase...
10136944 Systems and methods for treating cancer and/or augmenting organ function  
Systems, methods and devices for controlled sympathectomy procedures for neuromodulation in the treatment of subjects having neoplastic conditions are disclosed. Systems, methods, and devices for...
10134148 Method of assessing breast density for breast cancer risk applications  
Breast density is a significant breast cancer risk factor measured from mammograms. Disclosed is a methodology for converting continuous measurements of breast density and calibrated mammograms...
10132811 Salivary transcriptomic and microbial biomarkers for pancreatic cancer  
The present invention relates to the identification of pancreatic cancer biomarkers for the detection of early pancreatic cancer. The present invention also provides methods of diagnosing...
10132810 Method for assessing and predicting efficacy of breast cancer treatment with a long-acting topoisomerase I inhibitor  
Provided is a method of treating an individual suffering from a cancer such as breast cancer by administering to the individual a long-acting topoisomerase I inhibitor such as SN-38 or irinotecan,...
10131957 Breast cancer biomarkers and methods of using same  
The present invention provides breast cancer markers based on RECQL mutations, and related methods, uses, agents, and kits. The invention includes methods for determining the susceptibility of a...
10131956 Marker used for detection of colon cancer, and application thereof  
The present invention provides a marker used for detecting colon cancer, and also provides application of said marker in the detection of colon cancer, as well as an associated kit and detection...
10131953 Unbiased DNA methylation markers define an extensive field defect in histologically normal prostate tissues associated with prostate cancer: new biomarkers for men with prostate cancer  
A method of detecting the presence of a prostate cancer field defect in a human subject comprising the step of (a) obtaining genomic DNA from the human subject and (b) quantitating methylation in...
10130680 Methods for treating cancer with EGFR nanobodies linked to DR5 binding moieties  
The technology described herein is directed to methods and compositions directed to the treatment of cancer, e.g. using multifunctional receptor targeted cancer therapeutics.
10130679 SRPX for treatment of cancer  
Methods of treating a tumor in a subject include identifying a subject having, at risk for, or suspected of having a tumor, and administering to the subject an effective amount of an SRPX.
10130658 Method of ex vivo enhancement of immune cell activity for cancer immunotherapy with a small molecule ablative compound  
A cancer immunotherapy method is disclosed in which “induced immune anticancer agents” are isolated after being induced in an animal host by intralesional (IL) administration of a halogenated...
10130645 Use of thiopyrimidinecarboxamide for treating cancer  
There is disclosed is a method of treating disease using compound having formula SX-682 alone or in combination with an antineoplastic agent, microtubule affecting agents, antineoplastic agents,...
10130611 Use of benzo-heterocycle derivatives for preventing and treating cancer or for inhibiting cancer metastasis  
This application relates to a novel benzo-heterocycle derivative and more particularly, it relates a composition for preventing and treating cancer or for inhibiting metastasis comprising...
10130598 Methods and compositions for administration of 3-halopyruvate and related compounds for the treatment of cancer  
The present disclosure relates to the discovery that compounds of the invention, particularly 3-bromopyruvate and related compounds, can be safely administered at concentrations effective for the...
10130590 Methods of treating cancer with atovaquone-related compounds  
Described herein are, inter alia, methods for decreasing the growth of a cancer cell, the method comprising delivering to a target cancer cell a growth-inhibitory amount of an atovaquone-related...
10126311 Methods and compositions for detecting endometrial or ovarian cancer  
Some embodiments of the present invention relate to methods and compositions for assessing the absence, presence, progression, or stage of cancer. In particular, methods and compositions for...
10125196 Monoclonal antibodies for treatment of cancer  
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing GT468, including tumor-related diseases such as breast...
10125160 Method of making cobalt and platinum based surfactants and using for cancer therapy  
A method of making benzidine hydrogen selenite complex with Cobalt and Platinum as surfactants is discussed. The resultant benzidine hydrogen selenite complex with either Cobalt or Platinum was...
10125099 MAO inhibitors and their conjugates as therapeutics for the treatment of brain cancer  
A pharmaceutical composition and method for treating brain cancer are provided. The method includes administering to a patient in need thereof an effective amount of one or more compounds that...
10124079 Imaging of metastatic or recurrent cancer  
The present disclosure relates to methods of administering [18F]-FACBC. The present disclosure also relates to use of [18F]-FACBC in methods for imaging, diagnosing and monitoring metastasis or...
10124022 Compositions and methods for enhancing the effectiveness of systemic, HIPEC, IP, and related cancer treatments  
Methods for treating cancers, tumors, and neoplasms using a composition comprising one or more generally regarded as safe (GRAS) compounds selected from the group of components consisting of...
10124003 Therapeutic agent for FGFR inhibitor-resistant cancer  
The problem to be solved by the present invention is to provide an anticancer agent for treating tumors resistant to other antitumor agents that inhibit FGFR, and a method for treating such...
10123982 Receptor subtype and function selective retinoid and rexinoid compounds in combination with immune modulators for cancer immunotherapy  
Disclosed herein are methods for treating cancer comprising administering at least one immune checkpoint inhibitor and at least one Retinoic Acid Receptor or Retinoid X Receptor active agent.
10123973 Liposome composition for cancer treatment  
Disclosed is a liposomal composition for treatment of cancer, which includes at least one PEG-Phospholipid conjugated molecule, cholesterol, and at least one phospholipid.
10119960 Method of screening cancer cells using wrinkle patterns on a thin membrane  
Systems and methods for performing cancer screening assays are disclosed. The disclosed systems and methods use a thin film comprising cross-linked polysiloxane. At least a portion of a biological...
10119171 Method for the diagnosis, prognosis and treatment of prostate cancer metastasis  
The present invention relates to a method for the diagnosis or the prognosis of metastasis, relapse or recurrence in prostate cancer which comprises determining if the c-MAF gene is amplified in a...
10119137 Methods used to treat cancer  
The invention encompasses methods used in the sensitization and treatment of cancer based upon the expression of SGEF.
10118966 Anti-EGFR monoclonal antibody, methods of making, and uses thereof in the treatment of cancer  
The present invention provides a method for producing an anti-EGFR monoclonal antibody and the applications thereof. The method comprises the steps of: designing and synthesizing the light chain...
10118938 Arsenoplatin anti-cancer agents  
Disclosed herein are methods of treating a cancer cell that include contacting a cancer cell with a compound having the structure of formula (I) M is Pt, Pd or Ni; Q is As, Sb or Bi; Z1 is N; Z2...
10118052 Charged particle cancer therapy installation system  
The invention comprises a method for installing a proton based cancer therapy system in a hospital related brownfield building, comprising the steps of: (1) transporting gantry system elements to...