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10000539 Peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10000505 Anti-cancer agents and preparation thereof  
Embodiments of the present invention provide, among other compounds, a family of spliceosome-inhibiting compounds that can be used as therapeutic anti-cancer agents. The compounds are synthesized...
10000449 Bisarylsulfonamides useful in the treatment of inflammation and cancer  
A compound of formula (I) useful for the treatment of cancer, inflammation and inflammatory disorders, and a pharmaceutical composition containing the compound.
9999760 DVDMS sensitizer for cancer sonodynamic therapy  
A method for treatment of hyperproliferative tissue by injection of and subsequently exposing the hyperproliferative tissue to a frequency of ultrasound. The invention further includes purified...
9999669 Pharmaceutical composition for intestinal cancer treatment and/or prevention  
A method for treatment and/or prevention of intestinal cancer is provided, and the method includes: administering a composition to a subject in need thereof, the composition comprising a...
9999655 Use of MKS inhibitor peptide-containing compositions for treating non-small cell lung cancer with same  
Pharmaceutical compositions, systems and methods for treating a non-small cell lung cancer (NSCLC) solid tumor comprising a population of tumor cells are described. In some aspects, administering...
9999620 CaMKK-β as a target for treating cancer  
Provided herein are compounds, compositions, including pharmaceutical compositions, having anti-cancer activity. Also provided are methods for diagnosing, detecting, and treating cancer in a...
9999603 Compositions and methods including leelamine and arachidonyl trifluoromethyl ketone relating to treatment of cancer  
The present invention relates to compositions and methods for treatment of proliferative disease. In specific aspects, the present invention relates to compositions including...
9999598 Pharmaceutical composition for gastric cancer treatment and/or prevention  
A method for treatment and/or prevention of gastric cancer is provided, and the method includes: administering a composition to a subject in need thereof, the composition comprising a carbonaceous...
9995748 Biomarkers for prostate cancer comprising interleukin-8 (IL-8), tumor necrosis factor alpha and soluble tumor necrosis factor-alpha receptor 1  
The disclosure provides methods of using biomarkers to improve diagnosis of forms of prostate. The method includes testing a biological sample from an individual for a interleukin-8 (IL-8), Tumor...
9994912 Materials and methods for assessing progression of prostate cancer  
Methods of distinguishing and identifying a patient with aggressive/indolent, prostatic adenocarcinoma comprising contacting a sample from the patient with a set of detectably labeled probes under...
9994909 Diagnostic methods for determining prognosis of non-small cell lung cancer  
The invention provides methods for identifying early stage non-small cell lung cancer (NSCLC) patients who will have a favorable prognosis for the recurrence of lung cancer after surgical...
9994907 Thyroid cancer diagnostics  
Disclosed herein, in certain instances, are methods for the diagnosis, prognosis and determination of cancer progression of a cancer in a subject. Further disclosed herein, in certain instances,...
9994900 Composite biomarkers for non-invasive screening, diagnosis and prognosis of colorectal cancer  
The present invention concerns particular biomarkers for diagnosing and/or prognosticating colorectal cancer, in particular in a non-invasive manner. The methods and compositions concern analysis...
9994843 Method for assaying microRNA, cancer therapeutic agent, and medicinal composition containing same for cancer therapy  
The present inventors have found microRNAs which are strongly associated with stabilization of NRF2 in tumors, and an object of the present invention is to provide means for utilizing such miRNAs...
9994554 Barbiturate and thiobarbiturate compounds for use in cancer therapy  
Provided are methods and compositions for use in therapy, and in particular for treating cancer, preferably drug-resistant cancer, and/or radiation resistant cancer. The compounds may be used for...
9994550 Heterocyclic modulators of lipid synthesis for use against cancer and viral infections  
Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating...
9993567 Composition of anti-ENDO180 antibodies and methods of use for the treatment of cancer and fibrotic diseases  
The present invention provides antibodies or antigen-binding fragments thereof that specifically bind the ENDO180 polypeptide and are internalized thereby, to conjugates comprising the molecules,...
9993539 Peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers  
A method of treating a patient who has liver cancer (HCC), breast cancer (BRCA), melanoma, and/or uterine cancer includes administering to said patient a composition containing a population of...
9993523 Immunotherapy against several tumors including gastrointestinal and gastric cancer  
A method of treating a patient who has gastric cancer, gastrointestinal cancer, colorectal cancer, pancreatic cancer, lung cancer, and/or renal cancer includes administering to said patient a...
9993519 Anticancer peptide for inhibiting proliferation of cancer stem cells and use thereof  
The present invention relates to an anticancer composition comprising a peptide that inhibits the proliferation of cancer stem cells present in tumor tissue and that induces apoptosis of such...
9993495 Intrapulmonary administration of polynucleotide toll-like receptor 9 agonists for treating cancer of the lung  
The present disclosure relates to methods for treating cancer by intrapulmonary administration of a polynucleotide Toll-like receptor 9 agonist. The methods of the present disclosure are suitable...
9993482 Pharmaceutical combination comprising a class III receptor tyrosine kinase inhibitor and the alkylating histone-deacetylase inhibitor fusion molecule EDO-S101 together with its use in the treatment of cancer  
The present invention is directed to a combination comprising a class III receptor tyrosine kinase inhibitor and a compound of formula I or a pharmaceutically acceptable salt thereof: to a...
9993463 Use of maleimide derivatives for preventing and treating cancer  
The present invention is related to a compound of formula (I) a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, a metabolite thereof or a prodrug thereof; for use...
9988694 Effect of HBV on clinical outcome of hepatocellular carcinoma cancer patients  
A method for predicting prognosis (clinical outcome) of hepatocellular carcinoma patients based on the detection of a Hepatitis B virus, determination of the HBV genotype, identification of the...
9988690 Compositions and methods for prognosis of ovarian cancer  
Described herein are compositions and methods for the prediction of the prognosis of ovarian cancer subjects. The present invention further provides methods for distinguishing between histological...
9988688 Compositions for detecting mutant anaplastic lymphoma kinase in lung cancer  
Novel gene deletions and translocations involving chromosome 2 resulting in fusion proteins combining part of Anaplastic Lymphoma Kinase (ALK) kinase with part of a secondary protein have been...
9988687 Companion diagnostics for cancer and screening methods to identify companion diagnostics for cancer based on splicing variants  
A method of classifying a patient for eligibility for cancer therapy based on the presence or absence of splicing variants in a sample of the patient's cancer tissue. Also, a method of screening...
9988685 Methods and kits for diagnosing, prognosticating risk/outcome, and/or treating breast cancer  
Methods and kits for diagnosing, prognosticating risk of, and selecting and/or administering a therapy for breast cancer based upon detection of methylated glucocorticoid receptor gene or...
9988631 Pharmaceutical composition comprising Nanog shRNA, and method of using Nanog shRNA to treat cancer  
The present description relates to an inhibitory RNA molecule, comprising an oligonucleotide that selectively knocks down expression a Nanog pseudogene expressed in many human cancers, a...
9988403 Compositions and methods for treating cancer with aberrant lipogenic signaling  
The technology described herein relates to dimethyl boronate esters of the following formula for the treatment of cancers expressing abnormally high levels of SREBP1:
9987501 Extracting protobeams for cancer radiation therapy  
A method and system are provided. The method includes condensing, by a processor, an original voxel-beamlet matrix stored in a memory device into a reduced dataset for proton beam simulation and...
9987326 Klotho protein and related compounds for the treatment and diagnosis of cancer  
Disclosed is the use of a klotho protein or related compounds for the diagnosis and treatment of cancer, alone or together with other active pharmaceutical ingredients such as chemotherapeutic...
9987278 Pharmaceutical composition for treating FLT3 mutation-positive cancer, mutant FLT3 inhibitor and uses thereof  
Provided are a pharmaceutical composition for treating an FLT3 mutation-positive cancer; a mutant FLT3 inhibitor; and uses thereof. Disclosed are a pharmaceutical composition for treating an FLT3...
9987250 Compositions and methods for treating or preventing inflammatory bowel disease, familial adenomatous polyposis and colon cancer  
The present invention provides methods for preventing colon cancer by administering, to a patient in need thereof, a polymeric proanthocyanidin composition from a Croton species or Calophyllum...
9987241 Enzyme conjugate and prodrug cancer therapy  
A method and composition for treating a cancerous tumor in a subject by targeting the tumor's vasculature using an enzyme conjugate comprising a ligand which binds to endothelial cells in the...
9987089 Device and a method for imaging-guided photothermal laser therapy for cancer treatment  
This invention relates to a device and a method for monitoring and optimizing photothermal therapy, using a high-power continuous-wave laser beam and a pulsed laser beam, both transmitted through...
9984201 Method and system for determining cancer status  
Disclosed herein are methods, systems, platforms, non-transitory computer-readable medium, services, and kits for determining a cancer type in an individual. Also described herein include methods,...
9983209 Method of diagnosing, treating and determining progression and survival of cancer cells using BCL-2 antagonist of cell death (BAD) pathway gene signature  
The present invention relates to the BAD pathway's influence on development, progression, chemo-sensitivity, and overall survival for multiple human cancers and its potential as a therapeutic...
9983208 Composition for diagnosing pancreatic cancer and method for diagnosing pancreatic cancer using the same  
The present invention relates to: a composition for diagnosing pancreatic cancer, containing a preparation for measuring the expression level of a protein or a gene thereof, and capable of being...
9983194 Cancer diagnostics, therapeutics, and drug discovery associated with macropinocytosis  
The present invention is directed to methods of inhibiting both proliferation and survival of cancer cells and for treating a subject having cancer. The present invention is further directed to...
9982307 Methylation biomarkers for breast cancer  
Different combinations of methylation status based biomarkers can be used to test for breast cancer with high sensitivity and high specificity.
9982306 Somatic mutations in ATRX in brain cancer  
We determined the sequence of ATRX and DAXX in 447 cancers from various sites. We found mutations most commonly in pediatric glioblastoma multiformae (GBM) (11.1%), adult GBM (6.5%),...
9982305 Polymerase chain reaction test kits for detecting markers of bladder cancer  
This invention relates to the use of human neutrophil marker interleukin 8 receptor B (IL8Rb) for detection of bladder cancer, and more particularly to the use of EL8Rb for discriminating between...
9982304 ARID1A and PPP2R1A mutations in cancer  
Two genes, ARID1A (AT-rich interactive domain-containing protein 1A) and PPP2R1A (protein-phosphatase 2, regulatory subunit 1, alpha), can be used in methods which are useful for detecting cancer,...
9982043 Use of IL-20 antagonists for treating pancreatic cancer  
Methods for treating pancreatic cancer using an IL-20 antagonist, which can be an antibody that binds IL-20 or an IL-20 receptor, thereby blocking the signaling pathway mediated by IL-20.
9981974 Small molecules targeting androgen receptor nuclear localization and/or level in prostate cancer  
A method for treating prostate cancer in a subject, comprising administering a therapeutically effective amount of at least one agent to the subject, wherein the agent is selected from: (a) a...
9981968 Substituted pyrrolo[2,3-d]pyrimidines for the treatment of cancer and proliferative disorders  
Disclosed are substituted pyrrolo[2,3-d]pyrimidine compounds. The disclosed compounds are shown to be useful in inhibiting the growth of cancer cell lines and treating cancer and cell...
9981936 Isoflavonoid compositions and methods for the treatment of cancer  
Provided herein is a pharmaceutical composition comprising an isoflavonoid derivative and a cyclodextrin. Also provided herein are methods of treating cancer, sensitizing cancer cells, and...
9981915 Compounds for treatment of cancer  
The present invention relates to colchicine-binding site compounds having anti-cancer activity, compositions comprising the same, and their use for treating various forms of cancer.