Match Document Document Title
7575928 Genes for diagnosing colorectal cancer  
This invention relates to provide the genes for diagnosing colorectal cancer, the gene sequences searching comprise the steps of: (1) deriving epithelium cells from normal intestines, polypus of...
7575926 Method of identification of compounds effective against suppressed cancer cells  
A method for identifying compounds capable of targeting suppressed cancer cells, the method including the steps of comparing the response to a test compound of cancer cells grown on a suppressing...
7575749 Serpentine transmembrane antigens expressed in human cancers and uses thereof  
Described is a novel family of cell surface serpentine transmembrane antigens. Two of the proteins in this family are exclusively or predominantly expressed in the prostate, as well as in prostate...
7572923 Indirubin derivatives having anticancer property against human cancer cell line  
The present invention relates to an indirubin derivative having anticancer property by inhibiting cell proliferation as to human cancer cell line. More particularly, this invention provides the...
7572887 Gene expressed in prostate cancer, methods and use thereof  
A polypeptide is disclosed that is specifically detected in the cells of the prostate, termed Splice Variant-Novel Gene Expressed in Prostate (SV-NGEP). Polynucleotides encoding SV-NGEP are also...
7572816 Therapeutic agents for the treatment of cancer, metabolic diseases and skin disorders  
The present invention is directed to compounds having the structure wherein R 1 , R 2 , R 3 , R 4 , R 5 and m are as defined herein. The compounds of this invention are novel therapeutic agents...
7572814 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds  
Certain 3,5-dibenzoyl-4-phenyl-piperidine compounds and salts thereof are provided herein. The compounds and salts may be useful in causing mitotic arrest and cell death. Also provided herein are...
7572448 Combined cancer treatment methods using selected antibodies to aminophospholipids  
Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and compositions and methods for...
7570063 Space-time microwave imaging for cancer detection  
Microwave imaging via space-time beamforming is carried out by transmitting microwave signals from multiple antenna locations into an individual to be examined and receiving the backscattered...
7569711 Enone cancer therapeutics  
Described herein are new enone derivatives and conjugates. Additionally, methods for synthesizing these new enones are also disclosed. These compounds can be employed in cancer therapy.
7569662 Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of lung cancer  
Novel markers for lung cancer that are both sensitive and accurate. These markers are overexpressed in lung cancer specifically, as opposed to normal lung tissue. The measurement of these markers,...
7569554 Synergistic treatment of cancer using immunomers in conjunction with therapeutic agents  
The invention relates to the therapeutic use of immunostimulatory oligonucleotides and/or immunomers in combination with chemotherapeutic agents to provide a synergistic therapeutic effect.
7569551 Chemo- and radiation-sensitization of cancer by antisense TRPM-2 oligodeoxynucleotides  
Administration of antisense oligodeoxynucleotides (ODN) targeted against the testosterone-repressed prostate message-2 (TRPM-2) gene can reduce the amount of TRPM-2 in renal cell cancer (RCC) cells...
7569356 Diagnosis and therapy of cancer using SGP28-related molecules  
The present invention relates to methods and compositions for the diagnosis and therapy of prostate cancer which utilize isolated polynucleotides corresponding to the human SGP28 gene, proteins...
7569350 Methods for selecting cancer vaccine therapies using extracellular DNA  
This invention relates to detection of specific extracellular nucleic acid in plasma or serum fractions of human or animal blood associated with neoplastic or proliferative disease. Specifically,...
7569345 Gene expression markers for breast cancer prognosis  
The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer.
7569234 Herb composition for treating lung cancer and preparation method thereof  
The present invention provides a composition for treating cancers, which comprises (a) pharmaceutically acceptable carriers and (b) an effective amount of an aqueous or aqueous organic solvent...
7566542 Use of protein ASC as a marker for breast cancer  
The present invention relates to the diagnosis of breast cancer. It discloses the use of protein ASC in the diagnosis of breast cancer. It relates to a method for diagnosis of breast cancer from a...
7566452 Cancer treatment with endothelin receptor antagonists  
The present invention relates to therapeutic protocols and pharmaceutical compositions designed to treat and prevent cancer. More specifically, the present invention relates to a novel method of...
7563880 Compositions and methods for the therapy and diagnosis of breast cancer  
Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic...
7563570 Method of determining a chemotherapeutic regimen for non small cell lung cancer based on BRCA1 expression  
The present invention relates to a screening method for classifying patients and for selecting an effective chemotherapy for the treatment of a patient suffering from non-small-cell lung cancer...
7563448 Modified vaccinia ankara expressing P53 in cancer immunotherapy  
Mutations to the tumor suppressor protein p53 have been observed in 40-60% of all human cancers. These mutations are often associated with high nuclear and cytoplasmic concentrations of p53. Since...
7563446 Methods and compositions for inducing autoimmunity in the treatment of cancers  
Disclosed are methods and compositions for the prevention and treatment of cancers using lipid-carrier protein conjugate compositions for generating lipid-specific immune responses in an animal....
7563444 Nucleic acid and corresponding protein entitled 213P1F11 useful in treatment and detection of cancer  
A novel gene (designated 213P1F11) and its encoded protein, and variants thereof, are described wherein 213P1F11 exhibits tissue specific expression in normal adult tissue, and is aberrantly...
7563442 Antibodies to CD40 and methods of treating cancer and enhancing immune responses  
The present invention relates to antibodies and antigen-binding portions thereof that specifically bind to CD40, preferably human CD40, and that function as CD40 agonists. The invention also...
RE40862 Gossypolone for the treatment of cancer  
A method for treating cancer in a human, which comprises administering to the human subject an anti-cancer effective amount of a compound selected from gossypol, gossypol acetic acid, gossypolone,...
7560531 Cln101 antibody compositions and methods of use alone and in combination with prostate specific antigen and other cancer markers  
This invention relates to a method for assessing risk of prostate and/or ovarian cancer. Specifically, in one embodiment it relates to utilizing both Cln101 and Prostate Specific Antigen (PSA) in...
7560263 Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof  
The present invention is directed to phenylalanine ammonia-lyase (PAL) variants produced by prokaryotes, wherein such prokaryotic PAL variant has a greater phenylalanine-converting activity and/or...
7560095 Cancer specific monoclonal antibodies  
Novel monoclonal antibodies and binding fragments thereof specific to human breast cancer, lung cancer, colon cancer and other cancers. The monoclonal antibody does not bind to the cell surface of...
7557215 Anthraquinone compounds as anti cancer compounds  
Anthraquinone compounds of the general formula (I) or a salt thereof (Formula I) in which R 1 to R 4 are each selected from the group consisting of H, C 1-4 alkyl, X 1 , —NHR 0 N (R 5 ) 2 in...
7557204 CUDR as biomarker for cancer progression and therapeutic response  
Disclosed is a novel human gene designated CUDR. Provides is also a CUDR gene as a biomarker in the diagnosis of human cancers and a cancer therapy.
7557129 Cyanopyridine derivatives useful in the treatment of cancer and other disorders  
This invention relates to novel diaryl ureas, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and angiogenesis...
7557090 Anthracycline antibiotics and methods of treating cancer using the same  
The present invention discloses new and novel substituted anthracyclines with modified alkyl-aromatic ring substitutions on the C-3′ of the sugar moiety or modified or unmodified alkyl-aromatic...
7556929 Compositions and methods for screening anti-cancer agents in yeast  
Methods and kits for identifying novel anti-tumor agents are provided.
7556602 Breast cancer screening with adjunctive ultrasound mammography  
Ultrasound mammography in which an automated transducer scans the patient's breast to generate many images of thin slices that are processed into few images of thick slices that can be displayed...
RE40839 Taxol treatment of cancer  
The present invention is a method of treatment for a patient with cancer. In particular, it is a method of treating patients having lymphomas and breast cancer using the microtubule agent,...
7553948 Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of ovarian cancer  
Novel markers for ovarian cancer that are both sensitive and accurate. These markers are overexpressed and/or differentially expressed in ovarian cancer specifically, as opposed to normal ovarian...
7553859 Macrocycles for the treatment of cancer  
The present invention relates to new Macro-cycles of Formula (I), and their use for the treatment of cancer.
7550580 Compositions and methods for treatment of prostate and other cancers  
Therapeutic agents which target heat shock protein (hsp) 27 in vivo are used to provide treatment to individuals, particularly human individuals, suffering from prostate cancer and other cancers...
7550496 Compositions and methods for treating cancer  
Hypoxia-activated prodrugs can be used to treat cancer when administered alone or in combination with one or more anti-neoplastic agents.
7550450 Prostate cancer treatment  
The instant invention provides potent antiandrogen compounds, such as 3β-acetoxyandrost-1,5-diene-17-ethylene ketal and 3β-hydroxyandrost-1,5-diene-17-ethylene ketal, and methods for their use in...
7550262 PTPN11 (SHP-2) mutations and cancer  
Diagnostic and therapeutic applications for certain types of cancer and precancerous conditions, including those deriving from hematologic cells, are described. Of particular interest are those...
7550160 Composition for treating cancer cells and preparation method for the same  
A composition for treating cancer cells and a preparation method therefor are provided. The novel flavonoid compounds are obtained from natural plants, and more particularly the compounds have a...
7547691 [4-(Benzo[B]thiophen-2-yl) Pyrimidin-2-yl]-amine derivatives as IKK-beta inhibitors for the treatment of cancer and inflammatory diseases  
The present invention provides compounds of Formula I: useful in the treatment of cancer and inflammatory diseases.
7547673 Therapeutics for cancer using 3-bromopyruvate and other selective inhibitors of ATP production  
The present invention relates to methods of treating a cancerous tumor using selective inhibitors of ATP production. The present invention also relates to pharmaceutical preparations comprising...
7547455 Cancer and inflammatory disorder treatment  
Disclosed are extracts, compositions, and methods for treating cancer and inflammatory disorders. Also disclosed are methods for preparing extracts or compounds for treating the disorders.
7547441 PAI-2 conjugates for the treatment and imaging of cancer  
A method is described for detecting, visualizing, or treating cells, particularly cancerous cells, that express a uPA/uPAR complex. The method employs a PAI-2 conjugate molecule that comprises...
7544476 Identifying cancers sensitive to treatment with inhibitors of notch signaling  
The disclosure provides a method for identifying cancer tissue sensitive to treatment with an inhibitor of Notch receptor activation. The method comprises determining the level of HeyL gene...
7541437 Breast cancer resistance protein (BCRP) and the DNA which encode it  
The Breast Cancer Resistance Protein is described, as well as the cDNA encoding said protein. This protein has been found to confer resistance to cancer chemotherapeutic drugs.
7541196 Planar optical waveguide based sandwich assay sensors and processes for the detection of biological targets including early detection of cancers  
An assay element is described including recognition ligands adapted for binding to carcinoembryonic antigen (CEA) bound to a film on a single mode planar optical waveguide, the film from the group...