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10604481 (Thio, oxo and seleno) semicarbazone complexes with zinc and their use for treating cancer  
The invention provides organic complexes of Zn2+ that are useful for treating cancer, as well as compositions and kits comprising such complexes, and intermediate monomer compounds that are useful...
10604480 (Thio, oxo, and seleno) semicarbazone derivatives and their use for treating cancer  
The invention provides compounds of formula I and II and salts thereof, wherein R1, R2, Y, R3, and R4 have any of the meanings described in the specification, as well as compositions comprising...
10603381 Synthesis of nanocompounds comprising anatase-phase titanium oxide and compositions containing same for the treatment of cancer  
This invention relates to novel nanocompounds that are cytotoxic to tumor cells when combined with ultraviolet light, the nanocompounds comprising multilayered carbon nanotubes with anatase-phase...
10603335 Cancer treatment combination compositions, methods and uses  
The invention provides combinations and formulations including a luteinizing hormone-releasing hormone (LHRH) or a LHRH analog; and curcumin or a curcumin analog. LHRH or LHRH analog can be fused...
10603328 Methods of treating advanced prostate cancer  
Provided herein are methods for treating metastatic prostate cancer using anti-androgen compounds and radionuclide-labeled androgens.
10603322 Therapeutic targeting of casein kinase 1δ in breast cancer  
The invention provides a method of inhibiting casein kinase 1δ (CK1δ), comprising contacting the CK1δ with a compound of formula (I), as defined herein; such as compound SR-3029. We demonstrate...
10603314 Method for treating gefitinib resistant cancer  
The present invention is directed to methods for the treatment of gefitinib and/or erlotinib resistant cancer. An individual with cancer is monitored for cancer progression following treatment...
10598664 Epithelial quantitation of histologically normal prostate tissue predicts the presence of cancer in tissue biopsies  
A method of detecting the presence of a prostate cancer in a human subject comprising the steps of (a) obtaining a histologically normal prostate tissue sample from the patient and (b) quantifying...
10598663 Methods and biomarkers for analysis of colorectal cancer  
The present invention relates to methods and biomarkers (e.g., protein biomarkers) for detection of colorectal cancer in biological samples (e.g., tissue samples, biopsy samples, stool samples,...
10598653 Methods of blocking cancer stem cell growth  
Disclosed herein are antibodies against GPR49 and uses of such antibodies. The antibodies can be monoclonal, humanized, or fully human antibodies against GPR49, hybridomas or other cell lines...
10597730 Method of diagnosing cancer  
A method of diagnosing cancer in a mammal is provided. The method includes the steps of determining in a nucleic acid-containing sample from the mammal the degree of DNA methylation of a target...
10597729 Use of gene expression profiling to predict survival in cancer patient  
Gene expression profiling in multiple myeloma patients identifies genes that distinguish between patients with subsequent early death or long survival after treatment. Poor survival is linked to...
10597727 Stomach cancer detection kit or device, and detection method  
This invention relates to a kit or a device for the detection of stomach cancer and a method for detecting stomach cancer, and provides a kit or a device for the detection of stomach cancer,...
10597726 Breast cancer detection kit or device, and detection method  
It is intended to provide a kit or a device for the detection of breast cancer and a method for detecting breast cancer. The present invention provides a kit or a device for the detection of...
10597451 Methods of treating cancer with a P2X7 peptide  
The invention relates to purinergic (P2X) receptors, more specifically to P2X7 receptors, the generation of antibodies and the use of antibodies and immunogens that are capable of selectively...
10597434 Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC, SCLC and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10597433 Peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10597432 Peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10597398 Suppression and regeneration promoting effect of low molecular weight compound on cancer and fibrosis  
To obtain a novel therapeutic drug for a malignant tumor or fibrosis. Used is a compound represented by formula (1), a salt thereof, or a solvate thereof. Also used is a therapeutic drug for a...
10596275 Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells  
The invention relates to methods for producing papilloma-derived nanosphere particles that contain therapeutic, diagnostic, or other agents. The invention also provides nanosphere particle...
10596256 Monoclonal anti-GT 468 antibodies for treatment of cancer  
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing GT468, including tumor-related diseases such as breast...
10596243 Peptides and combination of peptides for use in immunotherapy against breast cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10596183 Pharmaceutical compositions and their use for treatment of cancer and autoimmune diseases  
Described herein are combination therapies for cancer (such as lymphoid malignancies) and immune diseases (such as autoimmune diseases and inflammatory diseases). The therapies comprise the...
10596169 Cancer treatment with combination of plinabulin and taxane  
This invention provides a novel cancer treatment method in which plinabulin (t-butyl-dehydrophenylahistin or NPI-2358) and a taxane compound (such as docetaxel) are used in combination. Our study...
10596162 Method for treating gefitinib resistant cancer  
The present invention is directed to methods for the treatment of gefitinib and/or erlotinib resistant cancer. An individual with cancer is monitored for cancer progression following treatment...
10596133 Treatment of cancer with specific RXR agonists  
A method of treating cancer is disclosed comprising administering to a patient in need of such treatment a RXR agonist at a level below the RAR activating threshold and at or above the RXR...
10596116 Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders  
Metal-bisphosphonate nanoparticles are disclosed. Also disclosed are pharmaceutical compositions including the metal-bisphosphonate nanoparticles, methods of preparing the metal-bisphosphonate...
10596112 Methods of using albumin-antibody nanoparticle complex compositions for treating cancer  
Described herein are compositions of antibodies and carrier proteins and methods of making and using the same, in particular, as a cancer therapeutic. Also described are lyophilized compositions...
10593529 Mass-spectral method for selection, and de-selection, of cancer patients for treatment with immune response generating therapies  
A method and system for predicting in advance of treatment whether a cancer patient is likely, or not likely, to obtain benefit from administration of a yeast-based immune response generating...
10591482 Method of assaying Apolipoprotein AI for the in vitro diagnosis of colorectal cancer  
A method assaying the levels of expression Apolipoprotein AI, Apolipoprotein AII, E-Cadherin, and Galectin-3 in a biological sample from a person having or suspected of having colorectal cancer....
10590487 Liver cancer detection kit or device, and detection method  
It is intended to provide a kit or device for the detection of liver cancer and a method for detecting liver cancer. The present invention relates to a kit or device for the detection of liver...
10590463 Diagnostic methods and kits for monitoring response to chemotherapy in ovarian cancer  
Provided are methods of determining a response to a chemotherapeutic agent in a subject with ovarian cancer, comprising: determining a RNA integrity value of a sample comprising ovarian cancer...
10590385 Method of producing natural killer cells and composition for treating cancer  
A method for producing natural killer cells is disclosed. The method comprises isolating peripheral blood mononuclear cells (PBMCs) from a blood sample; isolating at least one of CD56+ cells...
10590204 Recombinant human IgM-antibody effective against cancer cells  
A recombinant human monoclonal pentameric IgM antibody comprising the capability of oligospecific binding to purified ganglioside epitopes GD3, GM3, GD2 and GM1 and the capability of specific...
10590179 Peptide derived from GPC3, pharmaceutical composition for treatment or prevention of cancer using same, immunity inducer, and method for producing antigen-presenting cells  
The present invention provides a peptide containing 8 or more consecutive amino acid residues in an amino acid sequence of any of SEQ ID NOS: 1 to 11 and consisting of 11 or less amino acid residues.
10590166 Peptides useable for treating cancer  
Compounds comprising R-G-Cysteic Acid (i.e., R-G-NH—CH(CH2—SO3H)COOH or Arg-Gly-NH—CH(CH2—SO3H)COOH) and derivatives thereof, including pharmaceutically acceptable salts, hydrates, stereoisomers,...
10590163 Natural and synthetic compounds for treating cancer and other diseases  
This invention provides a method of synthesizing new active compounds for pharmaceutical uses including cancer treatment, wherein the cancers comprise breast, leukocytic, liver, ovarian, bladder,...
10590108 Benzimidazoles for use in the treatment of cancer and inflammatory diseases  
Provided herein are methods for treating, preventing, or ameliorating one or more symptoms of a condition, disorder, or disease mediated by a lipid kinase or a protein kinase with benzimidazoles,...
10589128 Treatment beam path verification in a cancer therapy apparatus and method of use thereof  
The invention comprises a method and apparatus for treating a tumor of a patient using positively charged particles, comprising the steps of: (1) providing an approved current version of a...
10588939 Method of treating a bladder cancer using a chimeric EGF-targeted bacterial toxin  
Provided is a method of treating a bladder cancer in an animal or human comprising: administering to an animal or human patient a therapeutic composition comprising a first fusion protein capable...
10588912 Methods of reducing mammographic breast density and/or breast cancer risk  
The present disclosure is directed to generally methods for treating mammographic breast density and/or breast stiffness in a patient in need thereof, such as a premenopausal or perimenopausal...
10588540 Portable apparatus for detecting breast cancer  
An apparatus for detecting abnormal masses such as breast cancer includes a measurement sensor configured to obtain a voltage at a first area of a first breast of a subject; a reference sensor...
10585102 Characterization of cancer using detection of activated leukocyte cell adhesion molecule (ALCAM) shedding  
The presently-disclosed subject matter includes labels for use in the identification of shed ALCAM in s sample from a subject. Further included are methods for characterizing, monitoring,...
10585101 Prostatic liquid biopsy for the detection of prostate cancer and benign prostatic hyperplasia  
Disclosed are methods to induce dislodgement of target prostatic cells from the prostate organ, collecting said cells, and subsequently examining the cell population. Such methods comprise the...
10585099 SRM/MRM assays for cancer  
Methods are provided for quantifying specific proteins directly in biological samples that have been fixed in formalin by SRM/MRM assay. Such biological samples are chemically preserved and fixed...
10584389 Cancer screening by detection of ultrastructural and molecular markers  
The present invention relates to detection of cancer, or assessment of risk of development thereof. In particular, the present invention provides compositions and methods detection of field...
10584388 Detection of chromosomal abnormalities associated with endometrial cancer  
The methods and compositions described herein address the need for diagnostic method that could be offered to women during yearly checkups to allow for early detection, diagnosis and...
10584341 Antagonistic PDL1 aptamers and their applications in cancer therapy  
Aptamers that bind to and antagonize PDL1 and uses thereof in enhancing immune activity (e.g., promoting T cell proliferation), treating cancer, and/or infectious diseases such as infections...
10584339 Tumor associated vaccines and compositions for disrupting tumor-derived immunosuppression for use in combination cancer immunotherapy  
In one embodiment, a single modality cancer immunotherapy regimen that includes a therapeutic composition is provided. Such a therapeutic composition may include a Salmonella strain comprising a...
10584170 Cancer immunotherapy by disrupting PD-1/PD-L1 signaling  
The disclosure provides a method for immunotherapy of a subject afflicted with cancer, comprises administering to the subject a composition comprising a therapeutically effective amount of an...