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9863953 Method for determining prognosis of cancer  
The present invention relates to a method for determining prognosis of cancer in a subject, which comprises the step of detecting phosphorylation of a tyrosine residue at position 2681 of TRIO in...
9863949 Method for predicting and evaluating responsiveness to cancer treatment with DNA-damaging chemotherapeutic agents  
Provided herein are methods directed to the prediction and early assessment of the efficacy of cancer treatment regimens, in particular in patients undergoing therapy with a DNA-damaging...
9863005 Endometrial phase or endometrial cancer biomarkers  
Methods for detecting endometrial diseases or an endometrium phase in a subject are described comprising measuring endometrial markers or polynucleotides encoding the markers in a sample from the...
9863002 Genetic determinants of prostate cancer risk  
Described are methods of determining if a subject has a genetic predisposition to developing prostate cancer (PCa), e.g., an American or Caribbean subject of African descent and of reducing their...
9862944 Antisense oligonucleotides for treatment of cancer stem cells  
The invention provides oligonucleotides complementary to a non-coding chimeric mitochondrial RNA as well as compositions and kits comprising the same, and their use in treating and preventing...
9862774 Pharmaceutical composition for treatment and/or prevention of cancer  
It is intended to provide a CAPRIN-1-targeting antibody superior in antitumor activity to conventional antibodies, and use thereof as a therapeutic and/or preventive agent for a cancer. The...
9862714 Methods and compositions useful in treating cancer and reducing Wnt mediated effects in a cell  
Provided herein are novel compounds, pharmaceutical compositions for use, inter alia, in methods of reducing Wnt-mediated effects and treating cancer.
9862693 Compounds and methods of treating cancer  
Presented herein inter alia are novel compounds and methods of using the same for the treatment of cancers.
9862692 Highly selective anti-cancer agents targeting non-small cell lung cancer and other forms of cancer  
Described herein are analogs of 2-methyl-3-(2-ethynylthiazol-4-yl)cyclopent-2-enol and the corresponding ketone 3-(2-ethynylthiazol-4-yl)-2-methylcyclopent-2-enone, the analogs having terminal...
9861679 Method of treating cancer  
The present invention provides a method of treating cancer in a subject wherein the method comprising administering to the subject an IAP antagonist and a p38 and/or a MK2 inhibitor.
9861653 Synergistic anti-cancer composition and a process for the preparation thereof  
The present invention provides an anti-cancer lipid-based composition that kills very aggressive pancreatic cancer cells and breast cancer stem cell (CSC)-like cells. This composition is a...
9861625 Methods and compositions for treating cancer through inhibition of PI3K  
Provided herein are methods for treating cancer relating to inhibition of PI3K, as pharmaceutical compositions comprising a PI3K inhibitor and a PAK1 inhibitor.
9861624 Method of treating cancer  
This invention is directed to the treatment of cancer, particularly castration-resistant prostate cancer and osteolytic bone metastases, with a dual inhibitor of MET and VEGF.
9861342 Adjunctive ultrasound processing and display for breast cancer screening  
An adjunctive ultrasound mammography system and associated methods use an adjunctive ultrasound display configured for quick, intuitive, interactive viewing of volumetric ultrasound scans,...
9858665 Medical imaging device rendering predictive prostate cancer visualizations using quantitative multiparametric MRI models  
A user-independent, quantitative, multiparametric MRI model is developed and validated on co-registered correlative histopathology, yielding improved performance for cancer detection over single...
9858389 Method and system for determining the risk of occurrence of prostate cancer  
Clinical information, molecular information and/or computer-generated morphometric information is used in a predictive model for predicting the occurrence of a medical condition. In an embodiment,...
9857375 Cancer marker and utilization thereof  
The present invention provides a novel cancer marker that is useful in the diagnosis of urothelial cancer. The present invention uses ubiquilin 2 as a cancer marker for urothelial cancer (renal...
9857374 Biomarkers for the early detection of breast cancer  
The present invention provides reagents and methods for breast cancer detection.
9857360 Cancer analysis system  
The invention provides for detecting target subpopulations of cells that have high proliferative and renewal properties in animals, including circulating tumor cells, cancer stem cells,...
9856536 Method for treating castration-resistant prostate cancer  
Methods and kits for characterizing a subject having a steroid-dependent disease such as prostate cancer are described. A method of treating a steroid-dependent disease in a subject by obtaining a...
9856533 Predicting breast cancer treatment outcome  
Methods and compositions are provided for the identification of expression signatures in ER+ breast cancer cases, where the signatures correlate with responsiveness, or lack thereof, to treatment...
9856320 Cancer immunotherapy by disrupting PD-1/PD-L1 signaling  
The disclosure provides a method for immunotherapy of a cancer patient, comprises administering to the patient an Ab that inhibits signaling from the PD-1/PD-L1 signaling pathway, or a combination...
9856291 Cancer stem cell targeting peptide and use thereof  
A synthetic peptide that targets cancer stem cells is provided. The peptide consists of the amino acid sequence of anyone of SEQ ID NO: 1 to SEQ ID NO: 15. Also provided is a composition...
9856260 Compounds useful for inhibiting metastasis from cancer and methods using same  
The present invention includes compositions that are useful in preventing or treating metastasis in a subject diagnosed with cancer. The present invention also includes methods of preventing or...
9856255 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer  
The specification generally relates to compounds of Formula (I): and pharmaceutically acceptable salts thereof, where R1, R2, R3, R4 and R5 have any of the meanings defined herein. The...
9855349 Selectin ligands useful in the diagnosis and treatment of cancer  
The present invention provides methods and compositions useful in the diagnosis and treatment of cancer. More specifically, the present invention provides compositions and methods of use...
9855348 Radio-labelled antibody fragments for use in the prevention and/or treatment of cancer  
The application provides polypeptides comprising or essentially consisting of at least one heavy chain variable domain of a heavy chain antibody (VHH) or functional fragments thereof, wherein said...
9855347 Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells  
The invention relates to methods for producing papilloma-derived nanosphere particles that contain therapeutic, diagnostic, or other agents. The invention also provides nanosphere particle...
9855342 Targeting ABCB5 for cancer therapy  
The invention relates to methods for treating a subject by manipulating ABCB5 on a cell as well as related products. The methods include methods of treating cancer using ABCB5 binding molecules...
9855316 Granulocyte-macrophage colony stimulating factor for enhancing pulmonary host defense in acute and chronic radiation syndrome, therapeutic radiation intervention and cancer therapy  
Methods and compositions for treating and alleviating symptoms of irradiation injuries, therapeutic radiation intervention and/or anti-cancer therapies in a subject via pulmonary airway...
9855302 Treatment of cancer by manipulation of commensal microflora  
Provided herein are methods of treatment and/or prevention of cancer by manipulation of commensal microflora. In particular, the amount, identity, presence, and/or ratio of microflora (e.g., gut...
9855265 Methods for treating cancer with TrkA receptor tyrosine kinase antagonists  
The present disclosure relates to novel synthetic substituted heterocyclic compounds and pharmaceutical compositions containing the same, said compounds being capable of inhibiting or antagonizing...
9855261 Polymeric compound having camptothecin compound and anti-cancer effect enhancer bound thereto, and use of same  
The purpose of the present invention is to provide a polymeric compound in which a camptothecin compound and an anti-cancer effect enhancer, particularly a PARP inhibitor, are bound to a single...
9855255 Substituted naphthyridinyl hydrazines as anti-liver cancer agents  
The substituted naphthyridinyl hydrazine compounds as anti-liver cancer agents are anti-liver cancer agents that inhibit proliferative pathways of cancer cells, thereby exhibiting potent in vitro...
9855250 Method to treat lung cancer  
One example embodiment relates to a method of treating lung cancer by administering a compound of formula I to a subject in need thereof. Another embodiment relates to a method to treat Non-Small...
9855220 Methods of treating pancreatic cancer  
Provided herein are methods for the treatment of metastatic pancreatic cancer comprising administration of a composition comprising nanoparticles comprising a taxane (such as paclitaxel) and a...
9855216 Targeted nano-liposome co-entrapping anti-cancer drugs  
A liposomal composition includes at least two anti-tumor herbal drugs that are simultaneously co-encapsulated. Optionally, the liposomal composition is targeted by adding a monoclonal antibody is...
9851421 Differential atlas for cancer assessment  
Methods and apparatus associated with producing a quantification of differences associated with biochemical recurrence (BcR) in a region of tissue demonstrating prostate cancer (PCa) are...
9851363 Method for monitoring cancer and/or inflammatory reaction based on RelB phosphorylation  
The present Inventors demonstrated that the RelB subunit of NFκB plays a crucial role in promoting cell migration. More precisely, they identified that this pro-migratory activity is mediated by...
9851357 Method for the prognosis of survival time of a patient suffering from a solid cancer  
The present invention relates to an in vitro method for the prognosis of survival of a patient suffering from a solid cancer, comprising the quantification of the cell density of CD8+ cells and...
9850544 Genetic amplification of IQGAP1 in cancer  
We examined IQGAP1 copy gain and its relationship with clinicopathologic outcomes of thyroid cancer and investigated its role in cell invasion and molecules involved in the process. We found...
9850542 Gene signature to predict homologous recombination (HR) deficient cancer  
Methods for identifying and treating cancers that are homologous recombination (HR)-repair defective. In some aspects, HR defective cancers are treated with a PARP inhibitor therapy. Methods for...
9850541 Methods and kits for detecting subjects at risk of having cancer  
The present invention relates to agents and methods for screening, diagnosis and surveillance of cancer, in particular pancreatic cancer.
9850540 Method for detecting lung cancer using lung cancer-specific methylation marker gene  
The present invention relates to a method for detecting lung cancer using a lung cancer-specific biomarker, and more particularly to a biomarker for lung cancer diagnosis, which can detect...
9850313 Cancer biomarkers and methods of use thereof  
Methods and compositions for treating cancer, particularly breast cancer, are disclosed.
9850311 Compositions and methods for diagnosing and treating cancer  
An isolated antibody that specifically binds to an extracellular domain of two or more human FZD receptors and inhibits growth of tumor cells is described. Also described is a method of treating...
9850300 Compositions and methods relating to inhibiting cancer cell growth and/or proliferation  
The present invention determined that EGFL6 functions as a tumor vascular regulator of ovarian cancer stem cells (CSC). In addition, the present invention determined that a novel EGFL6 blocking...
9850293 Targeting trastuzumab-resistant HER2+ breast cancer with a HER3-targeting nanoparticle  
Disclosed herein are methods of treating cancer in a patient, the method comprising identifying a patient who is resistant to treatment with an anti-HER2 therapy; and administering to the patient...
9850273 Combination of estrogens plus antiprogestins with significant partial agonistic effect as an effective treatment of menopausal symptoms and for prevention of the occurrence of breast cancer  
Described herein are compositions and methods for hormone replacement therapy that address the shortcomings of the existing methods. Described herein are pharmaceutically effective partial...
9850221 Sulfated and unsulfated flavonoid oligomers as cancer therapeutics  
Sulfated and unsulfated flavonoid oligomers as inhibitors of cancer stem cells (CSCs) are provided. In particular, sulfated flavonoid dimers are shown to selectively inhibit CSCs growth and...