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9790507 Aptamers and use of the aptamers in the diagnosis and treatment of cancer  
The present invention relates to an aptamer comprising a nucleotide sequence SEQ ID NO: 1, a composition comprising an aptamer, and the use of the aptamer in the diagnosis and treatment of cancer,...
9790503 VHZ for diagnosis and treatment of cancer  
We provide VHZ for use in a method of treatment, prophylaxis or alleviation of a cancer, such as breast cancer, in an individual. We provide an anti-VHZ agent for the treatment, prophylaxis or...
9790500 Dual targeting antisense oligonucleotides as apoptotic inhibtor therapeutic compostions and methods for their use in the treatment of cancer  
Provided herein are compositions, method and uses for modulating IAP activity or for the treatment of cancer. The compositions comprise dual-targeting antisense oligonucleotides (dASO) for...
9790492 Agent for treating cancer  
[Problem] To provide the following: an agent for treating cancer, particularly an agent for inhibiting cancer cell proliferation or an agent for inhibiting or preventing cancer metastasis; drug...
9790274 Monoclonal antibodies targeting EpCAM for detection of prostate cancer lymph node metastases  
Embodiments of the invention provide high affinity recombinant EpCAM-binding antibodies. Methods of using a such antibodies as imaging agents, diagnostics and therapeutics are also provided....
9789202 Method for treating cancer using an interferon alpha conjugate  
A method for preventing or treating a cancer includes administering an anti-cancer pharmaceutical composition including an interferon alpha or a polymer conjugate thereof. The pharmaceutical...
9789193 Compositions for treating cancer and methods for making the same  
Described herein are compositions and methods relating to chemotherapeutic agent conjugates and the treatment of cancer.
9789182 Combination of anti-KIR and anti-CTLA-4 antibodies to treat cancer  
Provided are methods for clinical treatment of cancer (e.g., solid tumors or hematological malignancies) using an anti-KIR antibody in combination with an anti-CTLA-4 antibody.
9789173 Vaccine immunotherapy for treating cervical cancer in immune suppressed patients  
A method for overcoming mild to moderate immune suppression includes the steps of inducing production of naive T-cells and restoring T-cell immunity. A method of vaccine immunotherapy includes the...
9789171 Anti-fugetactic agents for the treatment of ovarian cancer  
This invention provides methods and compositions for modulating movement of eukaryotic cells with migratory capacity. More specifically, the invention provides anti-fugetactic agents and methods...
9789170 Arginine deiminase with reduced cross-reactivity toward ADI-PEG 20 antibodies for cancer treatment  
The present invention relates generally to isolated to arginine deiminase (ADI) proteins that have reduced cross-reactivity with anti-ADI-PEG 20 antibodies as compared to ADI-PEG 20, but which can...
9789159 Diagnosis and treatment of prostate cancer  
The methods of the present disclosure are directed toward methods of diagnosis and treatment of cancer in a subject. The present disclosure provides methods of diagnosing abnormal cells in a...
9789156 Combination anti-human epidermal growth factor receptor 2 (anti-HER2) cancer therapy using mucin 1 (MUC1) peptides and hemotherapeutics  
The treatment of human epidermal growth factor receptor 2-positive (HER2+) cancers using a combination of anti-mucin 1 (anti-MUC1) therapy and anti-human epidermal growth factor receptor 2...
9789153 Composition for preventing cancer and treating cancer and intensifying the effects of other anticancer drugs  
This invention relates to a composition derived from Chinese herbal medicines, medicinal plants and extracts thereof, and to its use for preventing cancer and treating cancer and intensifying the...
9789096 Methods and compositions for selective and targeted cancer therapy  
Provided herein are methods and compositions for selective and targeted cancer therapy, in particular certain benzothiophenes, benzothiazoles, oxalamides, N-acyl ureas and chromones, and their use...
9784743 Collagens as markers for breast cancer treatment  
The specification provides methods of determining whether a subject suffering from ER+/HER2+ breast cancer is likely to respond to adjuvant and neoadjuvant chemotherapy and methods of treating a...
9784666 Methods for assessing cancer cells using granulometry  
A method of measuring a characteristic optionally a clinical characteristic of a cancer test cell sample comprising: characterizing nuclear organization of DNA of the test cell sample: obtaining...
9783857 Diagnosis kit and chip for bladder cancer using bladder cancer specific methylation marker gene  
The present invention relates to a kit and nucleic acid chip for diagnosing bladder cancer using a bladder cancer-specific marker gene. More particularly, the invention relates to a kit and...
9783855 Cancer screening by detection of ultrastructural and molecular markers  
The present invention relates to detection of cancer, or assessment of risk of development thereof. In particular, the present invention provides compositions and methods detection of field...
9783853 Recurrent gene fusions in cancer  
The present disclosure relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present disclosure relates...
9783808 Ovarian cancer-specific aptamers and applications thereof  
The present invention provides ovarian cancer-specific aptamers, which are selected in vitro using SELEX and a microfluidic chip system. The aptamers can also bind to different...
9783795 Multi-epitope peptide-loaded dendritic cell immunotherapy for cancer  
Peptides of from about 7 to about 50 amino acid residues in length that have epitopes that bind to more than one HLA class II protein and stimulate CD4+ T cells for treatment of cancer from one of...
9783615 Combination treatment of cancer  
The present invention provides MT4-MMP inhibitor and EGFR inhibitor for use in the treatment of cancer, wherein said MT4-MMP inhibitor and EGFR inhibitor are different from each other. MT4-MMP...
9783608 Humanized antibodies to LIV-1 and use of same to treat cancer  
The invention provides humanized antibodies that specifically bind to LIV-1. The antibodies are useful for treatment and diagnoses of various cancers as well as detecting LIV-1.
9783519 Palladium/silver co-catalyzed tandem reactions synthesis of phenylacetophenone derivatives by oxabenzonorbornadienes with terminal alkynes and their anti-tumor or anti-cancer activities  
This invention relates to the quick and efficient synthesis of anti-tumor or anti-cancer compounds. More particularly, it relates to the quick and efficient synthesis of anti-tumor or anti-cancer...
9782427 Methods for treating cancer using TOR kinase inhibitor combination therapy  
Provided herein are methods for treating or preventing a cancer, comprising administering an effective amount of a TOR kinase inhibitor having the following formula (I): and an effective amount of...
9782418 Rationale-based design of a targeted therapy for cancer  
The methods, compositions, and kits of the invention are related to the discovery that lestaurtinib reduces levels and pathway activity of an SPOP substrate. Accordingly, described herein are...
9782409 Treatment of cancer and benign proliferative disorders  
Disclosed herein are compositions comprising lopinavir alone or in combination with ritonavir for use as a medicament in the treatment of cancer or benign proliferative disorders (warts) or in the...
9782393 Pharmaceutical compositions and methods for treating cancer and biomarkers for drug screening  
A pharmaceutical composition comprising sorafenib and GW5074. Said combination therapy inhibits cancer cell growth via c-Raf-PP2A-DAPK signaling transduction pathway in either in vitro or in...
9782380 Method for treating ovarian cancer and/or Hodgkin lymphomia with a gold(III) complex  
A method for treating cancer and gold(III) complexes with diaminocyclohexane ligand as anticancer agents. Also described are a pharmaceutical composition incorporating the gold(III) complexes and...
9779499 Grading of glandular tissue cancer by detailed image analysis of stained tissue slices  
An improved histopathological score is obtained by identifying objects in images of glandular tissue from cancer patients. The objects are identified based on staining by a biomarker. The score...
9779283 Automated prostate tissue referencing for cancer detection and diagnosis  
This application provides to a method for identifying one or more prostate tissue samples in a database that are closest to a test prostate sample, which can be used to aid pathologists when...
9779213 System for evaluating a pathological stage of prostate cancer  
Clinical information, molecular information and/or computer-generated morphometric information is used in a predictive model for predicting the occurrence of a medical condition. In an embodiment,...
9779204 Predictive test for aggressiveness or indolence of prostate cancer from mass spectrometry of blood-based sample  
A programmed computer functioning as a classifier operates on mass spectral data obtained from a blood-based patient sample to predict indolence or aggressiveness of prostate cancer. Methods of...
9777334 Cancer blood test using BC200 RNA isolated from peripheral blood for diagnosis and treatment of invasive breast cancer  
Compositions and methods for diagnosing an increased risk for the development of aggressive, invasive breast cancer are provided.
9777068 Method for treating a GD2 positive cancer  
The present invention relates to a method for treating a GD2 positive cancer by administering a preparation comprising an anti-GD2 antibody to a patient as a continuous intravenous infusion over...
9777061 Treatment of cancer using a CD33 chimeric antigen receptor  
The invention provides compositions and methods for treating diseases associated with expression of CD33. The invention also relates to chimeric antigen receptor (CAR) specific to CD33, vectors...
9776989 Chromone alkaloid dysoline for the treatment of cancer and inflammatory disorders  
The present invention relates to novel chromone alkaloid of formula 1 isolated from the plant Dysoxylum binectariferum. The compound...
9775916 Anti-DLL3 antibody drug conjugates for treating cancer  
Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
9772286 Method for detection of urothelial cancer  
It is to provide a method for detecting urothelial cancer simply and with high accuracy. It is a method for detecting urothelial cancer comprising administering 5-aminolevulinic acid (ALA), a...
9771625 Monoamine oxidase inhibitors and methods for treatment and diagnosis of prostate cancer  
A mechanism of monoamine oxidases (MAOs) driven epithelium-to-mesenchymal transition (EMT) is disclosed. Also disclosed are methods for treating cancer by inhibiting or suppressing MAOs in cancer...
9771621 Method and kit for performing a colorectal cancer assay  
The present invention relates to method and kit for performing a colorectal cancer assay. Especially a method including extracting total RNA from a peripheral blood sample obtained from a patient...
9771618 Methods for treating breast cancer  
Clinical tests for testing therapeutic sensitivity of cancerous breast tissue and methods and kits for performing the same are described herein. Embodiments of the present invention are directed...
9771411 Method of treating cancer by administering EGFR and EGFR/IGFIR binding molecules  
The present invention relates to bispecific molecules comprising an EGFR binding domain and a distinct IGFIR binding domain for use in diagnostic, research and therapeutic applications. The...
9771404 Multi-level specific targeting of cancer cells  
A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13Rα2 binding ligand; at least one effector molecule (e.g., one, two, three or more...
9771356 Inhibitors of beta-hydroxylase for treatment of cancer  
The present invention relates to compounds which modulate (e.g., inhibit) the activity of beta-hydroxylase (e.g., Asparatyl (asparaginyl) β-hydroxylase (ASPH)), including novel...
9771347 Process for making compounds for use in the treatment of cancer  
Disclosed herein is a process of making a compound of formula I The compound of formula I is an inhibitor of MEK and thus can be used to treat cancer.
9771330 Pyrimidine compounds for the treatment of cancer  
Compounds of Formula I or II: are described, along with pharmaceutical compositions containing the same and methods of using such compounds for the treatment of cancer.
9770499 MSI-specific frameshift peptides (FSP) for prevention and treatment of cancer  
Described is a vaccine for prevention and treatment of cancer characterized by microsatellite instability (MSI). The vaccine contains an MSI-specific frameshift peptide (FSP) generating humoral...
9770482 Targeting the EGFR-SGLT1 interaction for cancer therapy  
A compound can destabilize an epidermal growth factor receptor (EGFR) protein and a sodium/glucose co-transporter 1 (SGLT 1) protein. In one embodiment, the compound is a peptide derived from the...