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10220033 Substituted benzoxazepine for cancer therapy  
Implementations of the present invention include a compound and methods for inhibiting karyopherin beta 1 activity by administering to a patient in need thereof a therapeutically effective amount...
10220026 Micelle containing epirubicin-complexed block copolymer and anti-cancer agent, and pharmaceutical composition containing said micelle applicable to treatment of cancer, resistant cancer or metastatic cancer  
The problem addressed by the present invention is to develop a pharmaceutical having therapeutic efficacy against epirubicin-resistant tumors. The present invention provides a micelle having an...
10220024 Method of inhibiting cancer cell, method for detecting cancer cell, and system for detecting cancer cell  
An object of the present invention is to provide a cancer cell inhibitory drug, particularly a cancer stem-cell inhibitory drug, or a cancer stem-cell detection probe. A cancer cell inhibitory...
10220016 Methods and materials for assessing chemotherapy responsiveness and treating cancer  
This document provides methods and materials involved in assessing chemotherapy responsiveness and treating cancer (e.g., breast cancer). For example, methods and materials for determining whether...
10219997 Radiation sensitizer or anti-cancer chemotherapy sensitizer  
The present invention provides a novel radiosensitizer or anti-cancer chemotherapy sensitizer. In particular, the invention provides a radiosensitizer or anti-cancer chemotherapy sensitizer that...
10215830 Automated cancer detection using MRI  
Methods and systems for diagnosing cancer in the prostate and other organs are disclosed. Exemplary methods comprises extracting texture information from MRI imaging data for a target organ,...
10215756 Composition for diagnosing pancreatic cancer and method for diagnosing pancreatic cancer using the same  
The present invention relates to: a composition for diagnosing pancreatic cancer, containing a preparation for measuring the expression level of a protein or a gene thereof, and capable of being...
10215700 Plasmonic chip for observing cancer related substances by localized surface plasmon resonace  
A cancer-related substance in blood or a biological sample can be detected in a selective manner, so it becomes possible to determine the occurrence of cancer by observation of fluorescent image...
10214777 Molecular diagnostic test for cancer  
Methods and compositions are provided for the identification of a molecular diagnostic test for cancer. The test defines a novel DNA damage repair deficient molecular subtype and enables...
10214775 Prostate cancer associated circulating nucleic acid biomarkers  
The invention provides methods and reagents for diagnosing prostate cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated.
10214743 Colorectal cancer drug, and method for predicting prognosis of colorectal cancer patient  
The purpose of the present invention is to provide a colorectal cancer drug that uses microRNA exhibiting outstanding effectiveness in colorectal cancer patients, particularly colorectal cancer...
10214577 Peptides and combination of peptides for use in immunotherapy against esophageal cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10214558 Natural and synthetic compounds for treating cancer and other diseases  
This invention provides a method of synthesizing new active compounds for pharmaceutical uses including cancer treatment, wherein the cancers comprise breast, leukocytic, liver, ovarian, bladder,...
10214529 Small molecules for the treatment of primary cancer and cancer metastasis  
Certain embodiments and compounds are of the class of non-hydrolysable ATP analogs and adenosine receptor antagonists, useful for inhibiting the migration and growth of cancer cells.
10213515 Glycopeptide for contrast agent targeting cancer cells and contrast agent kit containing the same  
The present disclosure relates to a glycopeptide targeting cancer cells and a contrast agent kit containing the same. The glycopeptide is one wherein an azide reporting monosaccharide is bound to...
10213499 Peptides and combination of peptides for use in immunotherapy against breast cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10213454 Methods of inhibiting cancer stem cells with HMGA1 inhibitors  
The presently disclosed subject matter relates to methods of inhibiting cancer stem cells and growth of aggressive and/or poorly differentiated metastatic tumors comprising the cancer stem cells...
10213445 Compositions and methods of diazeniumdiolate-based prodrugs for treating cancer  
The present disclosure provides methods utilizing the diazeniumdiolate-based prodrugs for the treatment of cancer via various mechanisms and procedures. The disclosure also provides kits...
10213436 Methods of treating cancer using aurora kinase inhibitors  
Disclosed are methods for the treatment of various cell proliferative disorders. Disclosed in particular are methods for treatment of various cell proliferative disorders by administering a...
10213414 Glucocorticoid receptor modulators to treat pancreatic cancer  
Methods and compositions for treating a subject hosting a non-ACTH-secreting pancreatic tumor are disclosed. The methods include administering to the subject a chemotherapeutic agent and a...
10213401 Immunomodulatory and differentiating function selective retinoid and rexinoid compounds in combination with immune modulators for cancer immunotherapy  
Disclosed herein are methods for treating cancer comprising administering CAR-modified immune cells and at least one Retinoic Acid Receptor and/or Retinoid X Receptor active agent.
10213385 Combinational liposome compositions for cancer therapy  
The present invention provides methods for delivery of therapeutic agents to a subject using multi-component liposomal systems. The methods include administration of a therapeutic liposome...
10213128 UWB microwave imaging system with a novel calibration approach for breast cancer detection  
An apparatus and method for imaging a tissue. The method includes transmitting a first microwave frequency signal to and receiving a first total signal from the tissue at a first position. A...
10208354 NRG1 fusion genes in cancer  
The present invention relates to novel fusion genes comprising NRG1 and a further fusion partner, like CD74. The present invention provides for the use of these fusion genes in diagnosis as well...
10208353 Biomarkers useful for detection of types, grades and stages of human breast cancer  
The present invention relates to biomarkers useful for detection of types, grades and stages of human breast cancer. The present invention particularly relates to the development of these...
10208130 Quantifying Her2 protein for optimal cancer therapy  
Improved methods of treatment are provided for patients suffering from cancer. The methods identify whether a tumor will be responsive to treatment with a therapeutic regime that includes...
10208086 Cyclin A1-targeted T-cell immunotherapy for cancer  
Compositions and methods are provided for eliciting antigen-specific T-cell responses against human cyclin A1 (CCNA1), which is herein identified as a leukemia-associated antigen based on its...
10208028 Methods of treating cancer  
One embodiment is a method of treating cancer. The method includes administering a therapeutically effective amount of a compound to a patient. The compound is represented by Formula I:
10207988 Methods and compositions for treatment of cancer and autoimmune disease  
The technology described herein relates to methods of inducing cell death. The technology described herein further relates to treating conditions including cancers and autoimmune diseases...
10206990 Cytotoxic T lymphocyte inducing immunogens for prevention treatment and diagnosis of cancer  
The present invention relates to compositions and methods for the prevention, treatment, and diagnosis of cancer, especially carcinomas, such as pancreatic carcinoma. The invention discloses...
10206988 Xenoantigen-displaying anti-cancer vaccines and method of making  
Compositions, methods of making, and methods of using, xenoantigen-displaying anti-cancer vaccines are described.
10206987 Protein nanoparticle linked with cancer specific epitope and composition for cancer immunotherapy comprising the same  
The present invention relates to a protein nanoparticle having a surface on which a cancer-specific epitope is fused and expressed, a method for producing the same, and a composition for cancer...
10206985 WT1 peptide cancer vaccine composition for mucosal administration  
The present invention provides a cancer vaccine composition for mucosal administration for inducing cellular immunity, comprising (i) a WT1 peptide and/or a modified WT1 peptide; and (ii) a...
10206920 Pharmaceutical composition for treating cancer and a method of using the same  
The invention provides a pharmaceutical composition and a method for treating cancer, and the composition comprises a proteasome inhibitor and a nuclear export inhibitor. The composition has...
10206916 Cabozantinib salts and their use as anti-cancer agents  
The present invention relates to crystalline forms of cabozantinib succinate (Form A) and cabozantinib acetate (Form A-1) and to pharmaceutical compositions comprising said crystalline forms and...
10206910 Apilimod for use in the treatment of renal cancer  
The present disclosure relates to methods for treating renal cancer with apilimod and related compositions and methods.
10206875 Nanoemulsion compositions of taxoid drugs, and methods for the use thereof to target cancer cells and cancer stem cells  
A composition of an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate encapsulated in an oil-in-water nanoemulsion (NE) drug delivery system. A method of treating cancer by administering...
10203343 Diagnosis of cancer by detecting auto-antibodies against epidermal growth factor (EGF)  
The present invention relates to a method for diagnosis of a cancer, comprising the steps of (i) determining the level of antibodies against epidermal growth factor (EGF) in a sample from a...
10203329 Biofilm formation to define risk for colon cancer  
Methods of identifying subjects at increased risk of cancer, based upon detection of biofilms and/or biofilm-associated microbes within a subject, are disclosed. Therapies designed to prevent...
10202653 Compositions and methods for detecting markers associated with bladder cancer  
Compositions and methods for detecting bladder cancer are provided. In some embodiments, methods of monitoring recurrence of bladder cancer are provided. In some embodiments, the methods comprise...
10202463 Cell-based anti-cancer compositions with reduced toxicity and methods of making and using the same  
Isolated pluralities of T cells which recognize at least one epitope of an intestinal cancer antigen or CNS cancer antigen and pharmaceutical compositions comprising the same are disclosed....
10202458 IGF-1R antibody and its use as addressing vehicle for the treatment of cancer  
The present invention relates to an antibody, in particular a monoclonal antibody, capable of binding to IGF-1R, as well as the amino and nucleic acid sequences coding for said antibody. From one...
10202457 Anti-DEspR monoclonal antibody targeted therapy and imaging for cancer and stroke  
Provided herein are novel compositions comprising anti-DEspR antibodies and fragments thereof derived from 6G8G7 and 7C5B2 anti-DEspR variant antibodies, including fully human, composite...
10202437 Peptides and combination of peptides for use in immunotherapy against esophageal cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10202398 Benzimidazole derivatives as ERBB tyrosine kinase inhibitors for the treatment of cancer  
Provided herein are benzimidazole derivatives, for example, of Formula (I), and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or...
10202397 Anti-cancer compounds targeting Ral GTPases and methods of using the same  
Methods of inhibiting the growth or metastasis of a cancer in a subject by inhibiting a Ral GTPase in the subject, and small molecule inhibitors of Ral GTPases useful in the methods of the...
10202357 Class of quinolone heterocyclic aromatic molecules for cancer treatment  
The invention is directed to new class of quinolone heterocyclic aromatic molecules (Renotinibs) and their use in the treatment of cancer, in particular, cancer that harbor abnormal human...
10201651 Systems and methods for destroying cancer cells in blood  
An apparatus for destroying cancer cells in blood includes a vessel for accepting a flow of blood of a patient through the vessel, and a sound energy source coupled with the vessel for generating...
10201611 Pharmaceutical composition comprising estetrol derivatives for use in cancer therapy  
The present invention relates to a method of treating or preventing estrogen-sensitive tumours in a mammal, said method comprising the administration of a therapeutically effective amount of an...
10201530 Treatment of BRCA1-defective cancer or resistant cancers  
Provided herein are methods of treating cancer in a subject by administering COH29 ((N-(4-(3,4-dihydroxyphenyl)-5-phenylthiazol-2-yl)-3,4-dihyd roxybenzamide)). The methods of treating include...