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10132811 Salivary transcriptomic and microbial biomarkers for pancreatic cancer  
The present invention relates to the identification of pancreatic cancer biomarkers for the detection of early pancreatic cancer. The present invention also provides methods of diagnosing...
10132810 Method for assessing and predicting efficacy of breast cancer treatment with a long-acting topoisomerase I inhibitor  
Provided is a method of treating an individual suffering from a cancer such as breast cancer by administering to the individual a long-acting topoisomerase I inhibitor such as SN-38 or irinotecan,...
10131957 Breast cancer biomarkers and methods of using same  
The present invention provides breast cancer markers based on RECQL mutations, and related methods, uses, agents, and kits. The invention includes methods for determining the susceptibility of a...
10131956 Marker used for detection of colon cancer, and application thereof  
The present invention provides a marker used for detecting colon cancer, and also provides application of said marker in the detection of colon cancer, as well as an associated kit and detection...
10131953 Unbiased DNA methylation markers define an extensive field defect in histologically normal prostate tissues associated with prostate cancer: new biomarkers for men with prostate cancer  
A method of detecting the presence of a prostate cancer field defect in a human subject comprising the step of (a) obtaining genomic DNA from the human subject and (b) quantitating methylation in...
10130680 Methods for treating cancer with EGFR nanobodies linked to DR5 binding moieties  
The technology described herein is directed to methods and compositions directed to the treatment of cancer, e.g. using multifunctional receptor targeted cancer therapeutics.
10130679 SRPX for treatment of cancer  
Methods of treating a tumor in a subject include identifying a subject having, at risk for, or suspected of having a tumor, and administering to the subject an effective amount of an SRPX.
10130658 Method of ex vivo enhancement of immune cell activity for cancer immunotherapy with a small molecule ablative compound  
A cancer immunotherapy method is disclosed in which “induced immune anticancer agents” are isolated after being induced in an animal host by intralesional (IL) administration of a halogenated...
10130645 Use of thiopyrimidinecarboxamide for treating cancer  
There is disclosed is a method of treating disease using compound having formula SX-682 alone or in combination with an antineoplastic agent, microtubule affecting agents, antineoplastic agents,...
10130611 Use of benzo-heterocycle derivatives for preventing and treating cancer or for inhibiting cancer metastasis  
This application relates to a novel benzo-heterocycle derivative and more particularly, it relates a composition for preventing and treating cancer or for inhibiting metastasis comprising...
10130598 Methods and compositions for administration of 3-halopyruvate and related compounds for the treatment of cancer  
The present disclosure relates to the discovery that compounds of the invention, particularly 3-bromopyruvate and related compounds, can be safely administered at concentrations effective for the...
10130590 Methods of treating cancer with atovaquone-related compounds  
Described herein are, inter alia, methods for decreasing the growth of a cancer cell, the method comprising delivering to a target cancer cell a growth-inhibitory amount of an atovaquone-related...
10126311 Methods and compositions for detecting endometrial or ovarian cancer  
Some embodiments of the present invention relate to methods and compositions for assessing the absence, presence, progression, or stage of cancer. In particular, methods and compositions for...
10125196 Monoclonal antibodies for treatment of cancer  
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing GT468, including tumor-related diseases such as breast...
10125160 Method of making cobalt and platinum based surfactants and using for cancer therapy  
A method of making benzidine hydrogen selenite complex with Cobalt and Platinum as surfactants is discussed. The resultant benzidine hydrogen selenite complex with either Cobalt or Platinum was...
10125099 MAO inhibitors and their conjugates as therapeutics for the treatment of brain cancer  
A pharmaceutical composition and method for treating brain cancer are provided. The method includes administering to a patient in need thereof an effective amount of one or more compounds that...
10124079 Imaging of metastatic or recurrent cancer  
The present disclosure relates to methods of administering [18F]-FACBC. The present disclosure also relates to use of [18F]-FACBC in methods for imaging, diagnosing and monitoring metastasis or...
10124022 Compositions and methods for enhancing the effectiveness of systemic, HIPEC, IP, and related cancer treatments  
Methods for treating cancers, tumors, and neoplasms using a composition comprising one or more generally regarded as safe (GRAS) compounds selected from the group of components consisting of...
10124003 Therapeutic agent for FGFR inhibitor-resistant cancer  
The problem to be solved by the present invention is to provide an anticancer agent for treating tumors resistant to other antitumor agents that inhibit FGFR, and a method for treating such...
10123982 Receptor subtype and function selective retinoid and rexinoid compounds in combination with immune modulators for cancer immunotherapy  
Disclosed herein are methods for treating cancer comprising administering at least one immune checkpoint inhibitor and at least one Retinoic Acid Receptor or Retinoid X Receptor active agent.
10123973 Liposome composition for cancer treatment  
Disclosed is a liposomal composition for treatment of cancer, which includes at least one PEG-Phospholipid conjugated molecule, cholesterol, and at least one phospholipid.
10119960 Method of screening cancer cells using wrinkle patterns on a thin membrane  
Systems and methods for performing cancer screening assays are disclosed. The disclosed systems and methods use a thin film comprising cross-linked polysiloxane. At least a portion of a biological...
10119171 Method for the diagnosis, prognosis and treatment of prostate cancer metastasis  
The present invention relates to a method for the diagnosis or the prognosis of metastasis, relapse or recurrence in prostate cancer which comprises determining if the c-MAF gene is amplified in a...
10119137 Methods used to treat cancer  
The invention encompasses methods used in the sensitization and treatment of cancer based upon the expression of SGEF.
10118966 Anti-EGFR monoclonal antibody, methods of making, and uses thereof in the treatment of cancer  
The present invention provides a method for producing an anti-EGFR monoclonal antibody and the applications thereof. The method comprises the steps of: designing and synthesizing the light chain...
10118938 Arsenoplatin anti-cancer agents  
Disclosed herein are methods of treating a cancer cell that include contacting a cancer cell with a compound having the structure of formula (I) M is Pt, Pd or Ni; Q is As, Sb or Bi; Z1 is N; Z2...
10118052 Charged particle cancer therapy installation system  
The invention comprises a method for installing a proton based cancer therapy system in a hospital related brownfield building, comprising the steps of: (1) transporting gantry system elements to...
10117943 Synthetic antibody mimetic compounds (SYAMS) targeting cancer, especially prostate cancer  
The present invention relates to compounds which function as antibody mimetic compounds. These compounds are bifunctional/multifunctional compounds which contain at least one cancer cell binding...
10117919 Methods and materials for generating CD8+ T cells having the ability to recognize cancer cells expressing a HER2/neu polypeptide  
This document provides methods and materials for generating CD8− T cells having the ability to recognize cancer cells expressing a HER2/neu polypeptide. For example, methods and materials for...
10117905 Compositions and methods to prevent cancer with cupredoxins  
The present invention relates to compositions comprising peptides that may be variants, derivatives and structural equivalents of cupredoxins that inhibit the development of premalignant lesions...
10117903 Method for regulating cancer stem cell growth by inhibiting phosphorylation of 120th threonine residue of TSPYL5 protein, a composition containing the peptide sequence functioning to inhibit the phosphorylation and a use thereof  
The present invention relates to a peptide suppressing the phosphorylation of threonine (T120), the 120th residue of TSPYL5 (testis-specific Y-like protein 5), which is specifically as follows....
10117872 Tyrosine kinase inhibitors for use in a method of treating cancer in association with a reduced caloric intake  
A tyrosine kinase inhibitor (TKI) for use in a method for the treatment of cancer in a patient, wherein the method comprises subjecting the patient to reduced caloric intake, i.e a daily caloric...
10117852 Glucocorticoid receptor modulators to treat pancreatic cancer  
Methods and compositions for treating a subject hosting a non-ACTH-secreting pancreatic tumor are disclosed. The methods include administering to the subject a chemotherapeutic agent and a...
10114023 Method of enhancing the efficacy of anti-hepatocyte growth factor receptor breast cancer therapy by administering an inhibitor of menaINV  
Methods and compositions are provided for diagnosing or inhibiting invasion or metastasis of a cancer in a subject based on MenaINV.
10114022 Method for the diagnosis, prognosis and treatment of prostate cancer metastasis  
The present invention relates to a method for the diagnosis or the prognosis of metastasis in prostate cancer which comprises determining if the c-MAF gene is amplified in a primary tumor sample....
10113203 Diagnosis kit and chip for bladder cancer using bladder cancer specific methylation marker gene  
The present invention relates to a kit and nucleic acid chip for diagnosing bladder cancer using a bladder cancer-specific marker gene. More particularly, the invention relates to a kit and...
10113169 Methods and compositions for treating cancer using peptide nucleic acid-based agents  
The present invention provides compositions and methods for treating cancer with peptide nucleic acid agents. In some embodiments, the present invention provides methods and compositions relating...
10113159 Suppression of cancer  
The present invention relates to polypeptides for use in suppressing cancer and cancer disorders. The treatment employs use of a non-cytotoxic protease, which is targeted to the cancer cell, and,...
10111969 uPAR targeting peptide for use in peroperative optical imaging of invasive cancer  
There is provided a novel conjugate that binds to the cell surface receptor uPA (uPAR). The conjugate is based on a fluorescence-labeled peptide useful as a diagnostic probe to the surfaces of...
10111940 Prostate cancer vaccine  
Androgen receptor-based vaccines for eliciting an immune reaction in vivo against cells expressing androgen receptor are disclosed. The vaccines are useful in the treatment of prostate cancer....
10111913 Method of reducing the likelihood of skin cancer in an individual human being  
Compositions, systems and methods of improving the health of the microbiome of an individual's skin relate to the provision of skin contacting formulations containing beneficial bacteria and other...
10111901 Beta-glucan in combination with anti-cancer agents affecting the tumor microenvironment  
The present invention relates to the combination of soluble β-glucan and anti-cancer agents that affect the tumor microenvironment. Soluble β-glucan promotes an immunostimulatory environment,...
10111899 Intrapulmonary administration of polynucleotide toll-like receptor 9 agonists for treating cancer of the lung  
The present disclosure relates to methods for treating cancer by intrapulmonary administration of a polynucleotide Toll-like receptor 9 agonist. The methods of the present disclosure are suitable...
10111897 Compositions and methods for treating cancer with JAK2 activity  
Methods and compositions for diagnosing and treating JAK2 inhibitor resistant cancers are disclosed. In the disclosed methods, AKT and/or PI3K inhibitors, ERK/MEK inhibitors, BCL-XL protein...
10111896 Composition comprising a combination of DNA methylation inhibitor and a vitamin D receptor agonist for the treatment of drug resistant cancer or for the prevention of tumor relapse  
The present invention concerns a combination of (i) a DNA methylation inhibitor, and (ii) a Vitamin D receptor agonist, for simultaneous or sequential use in the treatment of a drug resistant...
10111892 Anti-cancer agent  
The anti-cancer agent of the present invention contains at least one kind of phosphine transition metal complex selected from a group of compounds represented by the following Formulae (1a) to...
10111878 N,6-bis(aryl or heteroaryl)-1,3,5-triazine-2,4-diamine compounds as IDH2 mutants inhibitors for the treatment of cancer  
Provided are compounds of formula (I), Wherein: ring A and ring B are each independently an optionally substituted 5-6 membered monocyclic aryl or heteroaryl. The compounds are inhibitors of...
10111874 Combination therapies for treatment of cancer  
Combination therapies for treatment of cancers associated with mutations in the KRAS gene are provided. Compositions comprising therapeutic agents for treatment of cancers associated with...
10111871 Nanoparticle drug delivery system and method of treating cancer and neurotrauma  
The invention provides pharmaceutical formulations of inhibitors for poly (ADP-ribose) polymerase (PARP) enzyme. The formulations can be used in the treatment and prevention of cancer as well as...
10111861 Treatment of breast cancer  
This disclosure describes the use of one or more compounds that fall within the scope of one or more structural formula I, II, III, IV, V, or VI for treating triple negative breast cancer....