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10077296 Methods and compositions for the treatment and prevention of cancer  
The instant invention provides compositions for the treatment of cancer. Specifically, the invention provides polypeptides and nucleic acid molecules comprising tumor-associated embryonic...
10077280 Mixed ligand gold(I) complexes as anti-cancer agents  
Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a...
10077261 Imidazolin-5-one derivative useful as FASN inhibitors for the treatment of cancer  
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including those mediated by inhibition of fatty acid synthase (FASN) enzyme,...
10076569 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Smallpox vaccine for cancer treatment
 
Disclosed herein are methods and compositions related to therapy for cancer. More specifically, the disclosed methods and compositions are related to the use of smallpox vaccine to induce an...
10076560 Peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10076534 Effective treatment of ovarian cancer using triciribine and related compounds  
The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat ovarian cancer by one or a combination of (i) administering triciribine only...
10076520 Use of tyrosine kinase inhibitor in cancer treatment  
The present invention provides methods for reducing apoptosis of non-cancerous cells during a cancer treatment and beneficial effects associated with reducing such apoptosis. In particular,...
D828218 Cancer pin  
10073100 Methods and compositions for the diagnosis and treatment of cancer  
The present invention relates to methods, kits, and compositions for detecting and/or diagnosing metastatic potential of cancer cells or for evaluating prognosis in a patient with cancer by...
10073099 Methods and diagnostics for cancer detection and treatment monitoring  
Methods and diagnostic compositions for monitoring ER− breast cancer are disclosed. In some aspects, a method for detecting ER− breast cancer in a subject comprises obtaining a subject sample from...
10072303 Methods and materials for treating endometrial cancer  
This document provides methods and materials for treating endometrial cancer. For example, methods and materials for identifying a female mammal as having endometrial cancer and surgically...
10072302 Cervical cancer diagnosing method and diagnostic kit for same  
There are provided an improved cervical cancer diagnosing method and a diagnostic kit for same. According to the present invention, it is possible to more rapidly and accurately provide a patient...
10072301 Means and methods for molecular classification of breast cancer  
The invention relates to a method of typing a sample from a breast cancer patient. More specifically, the invention relates to a method for classification of breast cancer according to the...
10072300 Kit for the prognosis of colorectal cancer  
A kit for the prognosis of colorectal cancer, which includes reagents related in detecting the expression level of any one or more genes of the following five genes: BST1, as shown in SEQ ID NO:1;...
10072298 Gene fusions and gene variants associated with cancer  
The disclosure provides gene fusions, gene variants, and novel associations with disease states, as well as kits, probes, and methods of using the same.
10072082 Cancer immunotherapy by disrupting PD-1/PD-L1 signaling  
The disclosure provides a method for immunotherapy of a subject afflicted with cancer, comprises administering to the subject a composition comprising a therapeutically effective amount of an...
10072073 Glycans as functional cancer targets and antibodies thereto  
A glycan having the structure galβ1-3GLcNacβ1-3Galβ1-4(Fucα1-3)GlcNAc (LecLex) which is attached to a lipid or protein backbone, and isolated binding members capable of binding thereto.
10072049 Transport agents for crossing the blood-brain barrier and into brain cancer cells, and methods of use thereof  
The present invention discloses methods and materials for delivering a cargo compound into a brain cancer cell and/or across the blood-brain barrier. Delivery of the cargo compound is accomplished...
10072021 Compound for inhibiting binding between DX2 protein and P14/ARF protein, and pharmaceutical composition for treating or preventing cancer disease containing same as effective ingredient  
Disclosed is a new compound that inhibits binding between a DX2 protein and a p14/ARF protein, a pharmaceutical composition including the new compound as an effective component for treating or...
10071954 Hydrogen peroxide-activated compounds as selective anti-cancer therapeutics  
Provided are compounds according to the following Formula I: The Formula I compounds are activated in the presence of hydrogen peroxide and are therefore selective anti-cancer therapeutics for...
10071945 Nuclear receptor modulators and their use for the treatment and prevention of cancer  
Disclosed are compounds which are nuclear receptor modulators that can act as antagonists to the androgen receptor, for example, a compound of Formula I: wherein R1 to R5 and X1 to X5 are as...
10071148 Immunotherapy against several tumors, such as lung cancer, including NSCLC  
The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present...
10071130 Methods and compositions related to Hsp90 inhibitors and breast cancer  
Embodiments of the invention are directed to methods of treating cancer cells, particularly breast cancer cells, such as chemo-resistant cells, with an Hsp90 inhibitor and an anticancer agent or...
10071076 Methods of treating cancer and other disorders  
Active compounds useful for inhibiting fatty acid synthase in a subject in need thereof are described. The active compounds are, in general, a 5-mercapto-1H-Indazole-4,7-dione or an analog...
10071066 Method of treating cancer using selective estrogen receptor modulators  
Disclosed herein are methods of treating subjects suffering from estrogen receptor positive cancer of the brain by administering a selective estrogen receptor degrader (SERM). Also disclosed are...
10071056 Cancer cell targeting using nanoparticles  
The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of...
10071051 WT1 peptide cancer vaccine composition for transdermal administration  
The present invention provides a cancer vaccine composition for transdermal administration for cellular immunity induction, comprising (i) a WT1 peptide and/or a modified WT1 peptide; and (ii) a...
10070831 Integrated cancer therapy—imaging apparatus and method of use thereof  
The invention comprises a positively charged particle based cancer therapy system integrated with at least one off-axis imaging system, where elements of the off-axis imaging system and the cancer...
10066268 Methods of diagnosing or treating prostate cancer using the ERG gene, alone or in combination with other over or under expressed genes in prostate cancer  
The present invention relates to oncogenes or tumor suppressor genes, as well as other genes, involved in prostate cancer and their expression products, as well as derivatives and analogs thereof....
10066026 Chimeric small molecules for the recruitment of antibodies to cancer cells  
The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The...
10066020 Methods of detecting cancer  
A method of detecting the presence of glioblastomas and/or recurrent glioblastomas in a subject in need thereof includes isolating CD14+ cells from a blood sample of the subject and determining...
10064929 Peptides and combination of peptides for use in immunotherapy against breast cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10064923 Therapeutic cancer vaccines derived from a novel dendritic cell line  
The invention is in the field of medical sciences. It provides means and methods for the treatment of cancer. More in particular, it provides cells and cell lines that can be developed into fully...
10064913 Immunotherapy against several tumors including gastrointestinal and gastric cancer  
The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present...
10064911 Peptides for treating cancer  
The present invention relates to peptides for inhibiting angiogenesis. The present invention also relates to methods of inhibiting angiogenesis and methods of treating disorders associated with...
10064885 Metabolic gene, enzyme, and flux targets for cancer therapy  
A novel pathway in cancer cell metabolism is identified. Targeting of any gene, protein, or enzyme that modulates activity or flux through this pathway, including, but not limited to IDH1,...
10064883 Lipiodol-based anti-tumour emulsion for treating cancer  
The present invention relates to a pharmaceutical composition including Lipiodol and a molecule with anti-tumor activity and secondarily a hydroxyethyl starch. The present invention also relates...
10064874 Methods of reducing mammographic breast density and/or breast cancer risk  
The present disclosure is directed to generally methods and/or compositions for treating mammographic breast density and/or breast stiffness in a patient in need thereof, such as a pre-menopausal,...
10064834 Carbidopa for the treatment of cancer  
The present invention includes a method of inhibiting or reducing mTOR signaling or inhibition of indoleamine dioxygenase-1 (IDO1) in a subject with a proliferative disease, which comprises...
10064823 Nanoparticulate compositions for targeted delivery of acid labile, lipophilic prodrugs of cancer chemotherapeutics and their preparation  
In one embodiment, the present application discloses synthetic LDL nanoparticles comprising mixtures of components selected from the group consisting of phospholipids, triglycerides, cholesterol...
10060926 Method for diagnosing and treating ovarian cancer  
Provided are a composition, a kit, and a method of predicting prognosis of ovarian cancer or a risk of recurrence of ovarian cancer. Provided are a composition for treating ovarian cancer or...
10059998 Microrna signature as an indicator of the risk of early recurrence in patients with breast cancer  
The invention relates to the field of oncology and cancer treatment. The invention relates to methods for predicting the risk of recurrence of breast tumors using the expression signature of...
10059740 Integrin interaction inhibitors for the treatment of cancer  
Integrin interaction inhibitors using a beta-turn promoter are described herein. These peptides are useful in treating cancer, such as multiple myeloma, by administering a therapeutically...
10059721 Substituted thieno[3,2-b]pyrazines for inhibiting cancer cell proliferation and inducing cancer cell apoptosis  
The present invention relates to a novel 4-(aryl)-N-(2-alkoxythieno[3,2-b]pyrazin-3-yl)-piperazin-1-c arboxamide derivative compound useful in the prevention or treatment of cancer; a preparation...
10059702 Inhibitors of LC3/ATG3 interaction and their use in the treatment of cancer  
The present inventors discovered that the molecule pyridinylthiazolamine (PTA) specifically prevents the protein-protein interaction of hLC3 with hAtg3 in vitro and in cell based assays. The...
10058688 Medicament, method, and drug delivery device for treatment of ovarian cancer  
Drug delivery devices, medicaments, and methods are provided for the intraperitoneal treatment of ovarian cancer. An implantable device for drug delivery includes an elongated, flexible device...
10058610 Methods for treating cancer by administering humanized pan-HER antibody compositions  
The invention relates to humanized recombinant antibodies targeting the EGFR family receptors EGFR, HER2 and HER3, compositions comprising at least one humanized anti-EGFR antibody, at least one...
10058591 Co-administration of a parvovirus and a cytokine for therapy of pancreatic cancer  
The present invention relates to a combination of a parvovirus and a cytokine, preferably IFNy, for use in treating pancreatic cancer, in particular a terminal stage of this disease.
10058587 Peptide composition for cancer treatment by inhibiting TRPV6 calcium channel activity  
The invention includes an isolated peptide comprising all or part of the amino acid sequence: EGKLSSNDTE GGLCKEFLHP SKVDLPR (SEQ ID NO: 1), wherein the peptide inhibits calcium channel activity....
10058527 Composition containing monoacetyldiacylglycerol compound as active ingredient for inhibiting blood cancer or metastasis  
The present invention relates to a composition containing a monoacetyldiglyceride compound as an active ingredient, for inhibiting blood cancer or metastasis, and a use thereof. The...