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8703211 Agent and method for treating cancer comprising strontium, amino acid(s) and mineral agent(s)  
The invention relates to the treatment and prophylaxis of cancer. In particular, the invention relates to a pharmaceutical agent comprising strontium, amino acid(s) and mineral element(s), and its...
8703120 Use of oncolytic herpes viruses for killing cancer stem cells  
The invention, in some aspects, relates to the selective killing of cancer stem cells by oncolytic Herpes virus mediated oncolysis. In some aspects, the invention relates to methods for treating a...
8697855 Anti-CD151 antibodies and their use in the treatment of cancer  
The present invention relates to new antibodies capable of binding specifically to the human CD151 protein, especially monoclonal antibodies of murine origin, which are chimeric and humanized, and...
8697668 Compositions and methods for preventing and treating cancer via modulating UBE1L, ISG215 and/or UBP43  
Compositions and methods of using compositions that induce UBE1L or a ubiquitin-like protein ISG15, or inhibit a deconjugase UBP43 to degrade oncogenic proteins and enhance apoptosis of cancer...
8697666 Anti-cancer oligodeoxynucleotides  
It is disclosed herein that suppressive OD Ns are of use for preventing or delaying the formation of a tumor, reducing the risk of developing a tumor, treating a tumor, preventing conversion of a...
8697373 Reagents and methods for use in cancer diagnosis, classification and therapy  
Methods and reagents for classifying HER2+ breast tumors and for identifying new HER2+ breast tumor classes and subclasses. Methods for correlating tumor class or subclass with therapeutic regimen...
8697368 Diagnostic marker for lung cancer comprising HPαR as active ingredient  
Disclosed is a diagnostic marker for lung cancer comprising HpαR as an active ingredient. Because blood, which is relatively easy to sample, is employed as a specimen, the diagnostic kit and...
8697366 Anti-cancer drug screening method using RORα  
The present invention relates to a method for screening an anticancer agent using RORα, the method comprising the steps of: culturing cells; bringing a potential substance into contact with the...
8697360 Genetic variants on CHR 11Q and 6Q as markers for prostate and colorectal cancer predisposition  
It has been discovered that certain polymorphic markers on chromosome 6 and chromosome 11 are indicative of a susceptibility to prostate cancer and colon cancer. The invention describes diagnostic...
8697358 Non-invasive method for diagnosis of prostate cancer  
The present invention relates on a non-invasive method for diagnosing prostate cancer and/or assessing the risk of a subject acquiring prostate cancer comprising the analysis of the expression of...
8697350 Biomarker combinations for colorectal cancer  
The present invention relates to methods and kits for the detection of predetermined biomarkers for early diagnosis and management of cancer, and in particular, colorectal cancer.
8697181 Multifunctional Fe3O4 cored magnetic-quantum dot fluorescent nanocomposites for RF nano-hyperthermia of cancer cells  
A magnetic oxide-quantum dot nanocomposite and methods of synthesizing it. In one embodiment, the magnetic oxide-quantum dot nanocomposite has at least one magnetic oxide nanoparticle coated with...
8697079 IgE antibodies for the treatment of cancer  
The present invention provides monoclonal IgE antibodies comprising Fc epsilon (ε) constant regions and variable regions comprising at least one antigen binding region specific for binding a...
8697075 Cancer specific antibody and cell surface proteins  
The present invention provides the amino acid and nucleic acid sequences of heavy chain and light chain complementarity determining regions of a cancer specific antibody. In addition, the...
8697072 Targeting ABCB5 for cancer therapy  
The invention related to methods for treating a subject by manipulating ABCB5 on a cell as well as related products. The methods include methods of treating cancer using ABCB5 binding molecules...
8691870 Use of isothiocyanates for treating cancer  
Novel Uses of small molecules, particularly, 6-methylsulfinylhexyl isothiocyanate and 6-methylsulfonylhexyl isothiocyanate, are disclosed herein. The two isothiocyanates are useful as lead...
8691851 Lanthanide metal complexes useful in treating cancer  
The present invention relates to a compound of formula (I). Provided is also a method of killing a cell that comprises administering the compound of formula (I). Provided is also a method of...
8691819 Alpha helix mimetic compositions for treating cancer and other CBP/catenin-mediated diseases and conditions  
Alpha-helix mimetic structures and compounds represented by the formula (I) wherein the general formula and the definition of each symbol are as defined in the specification, a compound relating...
8691801 Use of manzamine compounds in anti-cancer therapeutic regimens  
Manzamine compounds have been discovered to decrease cell dissociation and cell migration associated with the metastatic potential of cancer cells and a restoration of cancer cell susceptibility...
8691799 Materials and methods for treatment of cancer and identification of anti-cancer compounds  
The subject invention pertains to the treatment of tumors and cancerous tissues and the prevention of tumorigenesis and malignant transformation through the modulation of JAK/STAT3 intracellular...
8691232 Extending time to disease progression or survival in cancer patients  
The present application describes extending time to disease progression or survival in a cancer patient, where the patient's cancer displays HER activation, by treating the patient with a HER...
8691229 Method of PLSCR inhibition for cancer therapy  
The present invention relates to a method of using inhibitors of phospholipid scramblases (PLSCRs) for the prophylactic or therapeutic treatment of cancers. The PLSCR-inhibitors of the invention...
8691212 Therapeutic/prophylactic agent for prostate cancer  
Provided are a novel therapeutic agent and therapeutic method for prostatic cancers. More specifically, a prostatic cancer therapeutic/prophylactic agent having a viral envelope vector,...
8691189 Method of colorectal cancer detection by using radiolabeled anti-GRP78 peptide  
The present disclosure describes techniques used for colorectal cancer detection. Position and distribution of colorectal cancer tumor are detected through nuclear imaging. Alternatively, stage of...
8688197 Charged particle cancer therapy patient positioning method and apparatus  
The invention comprises a patient positioning and/or repositioning system, such as a laying, semi-vertical, or seated patient positioning, alignment, and/or control method and apparatus used in...
8686178 Derivative of 18β-glycyrrhetinic acid apt to suppress cancer cells  
The present invention is correlated with a derivative of 18β-glycyrrhetinic acid apt to suppressing cancer cells, which is selected from a group comprising of structure I and structure II: wherein...
8686112 Methods and compositions for the detection of cancer  
A molecular probe for use in detection of cancer cells expressing an Ig superfamily cell adhesion molecule that binds in a homophilic fashion in a subject includes a targeting agent that...
8686052 Targeting agent for cancer cell or cancer-associated fibroblast  
Disclosed are a novel therapeutic agent and a novel treatment method for cancer. Specifically disclosed are: a targeting agent for a cell selected from the group consisting of a cancer cell and a...
8686030 Anti-cancer extract and compounds  
The preset invention relates to a new approach for treating a cancer or fibrosis, such as Hepatocellular carcinoma, or liver fibrosis using an extract from a plant of Graptopetalum sp., Rhodiola...
8685983 Method of treating cancer with substituted amide derivatives  
Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically...
8685954 Methods and compositions for treating cancer using proteasome inhibitors  
The present invention relates to therapeutic compositions for treating cancer or preventing the growth of cancer cells, e.g., tumor growth, in a subject. The present invention also relates to...
8685941 Drug composition cytotoxic for pancreatic cancer cells  
Disclosed herein are compositions comprising a drug combination that comprises ZD and S3I-201, Das and S3I-201, ZD and AG490, or Das and AG490. The disclosed drug combinations target two or more...
8685929 Detecting CYP24 expression level as a marker for predisposition to cancer  
This invention pertains to the discovery that an amplification of the CYP24 gene or an increase in CYP24 activity is a marker for the presence of, progression of, or predisposition to, a cancer...
8685923 Fibrillar albumin for use in inhibiting cancer growth  
A method for inhibiting survival of cancer cells in a subject is disclosed. The method comprises administering to a subject in need thereof a therapeutically effective amount of fibrillar albumin....
8685641 Method of screening compounds for treating bladder cancer  
Objective methods for detecting and diagnosing bladder cancer (BLC) are described herein. In one embodiment, the diagnostic method involves determining the expression level of a BLC-associated...
8685416 Compositions and methods for the treatment of cancer  
Methods for inducing an immune response to a tumor in a subject are disclosed herein. These methods include selecting a subject with a tumor and administering a therapeutically effective amount of...
8685398 Chemokine binding polypeptides capable of inhibiting the course of autoimmunity, inflammation and cancer  
Novel polypeptides comprising a chemokine-binding peptide and an Fc fragment are disclosed. The polypeptides are capable of binding to certain chemokines so as to modulate their activity. These...
8685384 Recombinant cancer cell secreting modified heat shock protein-antigenic peptide complex  
The present invention relates to methods for purifying immunogenic, prophylactically and therapeutically effective complexes of modified heat shock proteins noncovalently associated with antigenic...
8684901 Electromagnetic radiation treatment for cancer and pathological genetic regulations  
An electromagnetic radiation treatment regime includes identifying a target area of a patient that comprises at least some cancer cells, or other cells amenable to pathological genetic...
8682693 Patient data mining for lung cancer screening  
A system and method for lung cancer screening is provided. The system includes a database including structured patient information for a patient population and a domain knowledge base including...
8682591 Biomarkers for ovarian cancer  
The present invention relates to a method of qualifying ovarian cancer status in a subject comprising: (a) measuring at least one biomarker in a sample from the subject and (b) correlating the...
8680282 Cyclic inhibitors of carnitine palmitoyltransferase and treating cancer  
A CPT1 inhibitor compound is represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof: or a pharmaceutically acceptable salt thereof. A pharmaceutical composition...
8680243 Diagnosis and treatment of cancer using anti-GPR49 antibody  
Antibodies that bind to a GPR49 protein and have cell proliferation inhibitory activity against cells expressing the GPR49 protein are disclosed. Cell proliferation inhibitory activities are...
8680152 Cathepsin inhibitors for the treatment of bone cancer and bone cancer pain  
The present invention is directed to methods of using compounds that are inhibitors of cysteine proteases, in particular, of both cathepsins S and K and optionally further cathepsins B and/or L in...
8680142 Ascorbate, vitamin K3 and hydroxytolans in the treatment of cancer  
The combination of compounds of the hydroxytolan family with ascorbate plus naphthoquinone (Vitamin K3; VK3), or a quinone or semiquinone analogue of VK3, kill tumor cells, inhibit tumor growth...
8680129 Compounds, composition, methods, targets for cancer therapy  
This invention describes methods and pharmaceutical compositions for combinational cancer treatments that are capable of inducing JNK phosphorylation and induce programmed cell death. It also...
8680126 Fluorinated thiazoles for use in treating cancer  
Compounds of formula (I) or their pharmaceutically acceptable salts, or their stereoisomers or mixtures of stereoisomers, where: R1 is selected from the group consisting of: phenyl, and phenyl...
8680067 Targeting microRNAs for the treatment of liver cancer  
Provided herein are methods for the treatment of liver cancer. These methods encompass the administration of a compound comprising a modified oligonucleotide, wherein the modified oligonucleotide...
8680055 Methods for decreasing steroidogenesis in prostate cancer cells  
The present invention discloses compositions and methods for treating diseases such as cancer by targeting luteinizing hormone (LH) or its receptor (LHR) involved in androgen synthesis or...
8680045 Compositions of a peptide targeting system for treating cancer  
This invention describes a protein nanoparticle system for targeting siRNA or other drugs into tumors. The basis of the protein system is elastin-like peptides that self-assemble once exposed to...