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9422303 Formulations of water-insoluble chemical compounds and methods of using a formulation of compound FL118 for cancer therapy  
Provided are compositions, methods of making the compositions, and methods of using the compositions. The compositions can be provided as pharmaceutical preparations for use in disease treatment,...
9422241 Demethylpenclomedine analogs and their use as anti-cancer agents  
This disclosure concerns novel demethylpenclomedine analogs. Also disclosed are pharmaceutical compositions and methods for using such compositions to treat hyperproliferative disorders. In one...
9422234 Prostate specific membrane antigen (PSMA) targeted nanoparticles for therapy of prostate cancer  
The invention provides a nanoparticle composition that is decorated with a urea-based small-molecule peptidomimetic inhibitor of prostate specific membrane antigen (PSMA), which is expressed by...
9421282 Method of preparing iodine seed for treating eye disease or cancer, and iodine seed prepared thereby  
The present invention provides a technique for adsorbing I-125 on a support for treating cancer and a method of preparing an I-125 seed using the same. Since a method of preparing iodine according...
9421264 Method of treating cancer using selective estrogen receptor modulators  
Disclosed herein are methods of treating subjects suffering from estrogen receptor positive cancer of the brain by administering a selective estrogen receptor degrader (SERM). Also disclosed are...
9421220 Anti-cancer composition comprising alginate  
Biologically acceptable composition for the prophylaxis and/or treatment of colorectal cancer. The composition contains an iron chelator, and the composition is adapted for the selective targeting...
9421203 Sensitization of cancer cells to DNA damage by inhibiting kinases essential for DNA damage checkpoint control  
The invention provides methods for overriding cell cycle arrest in a tumor cell, which comprise inducing DNA damage in the cell, and contacting the cell with an amount of bosutinib or a bosutinib...
9421193 Benzothiazole derivatives and a use thereof for the treatment of cancer  
Provided are a compound represented by Formula I, a pharmaceutically acceptable salt thereof, or a solvate thereof; and a pharmaceutical composition for cancer treatment and a pharmaceutical...
9417244 Cadherins as cancer biomarkers  
Methods of isolating, enriching, capturing, identifying, or detecting the presence of, cancerous cells in a sample, e.g., a blood sample from a subject, by detecting the presence of one or more...
9417242 Method and system for detecting and differentiating cancer and sepsis in mammals using biomarkers  
The invention provides a method and system for developing and using diagnoses of cancer and sepsis in canine subjects using thymidine kinase (TK), c-reactive protein (CRP), and C-type natriuretic...
9417241 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine (TCPP) and kit for use with detecting cancer  
Presented is a kit containing TCPP for use in prognosing a patient's response to a cancer therapy wherein prior to the therapy contacting a sample of cells from the patient's tissue or organ being...
9416410 Cutoff point delta Ct. method for HER2 PCR testing in breast cancer  
The present invention is related to an improved method for HER2 gene test by using quantitative real-time PCR (Polymerase Chain Reaction) technique. Our invention streamlines test process, and...
9416391 Method for identifying cancer drug candidates in Drosophila  
A process for preparing information that identifies a compound as capable of perturbing the epithelium in a D. melanogaster comprising the steps of: i) obtaining a D. melanogaster which is...
9416193 Pharmaceutical composition for treatment and/or prevention of liver cancer  
Provided is an antibody effective for treatment and/or prevention of liver cancer. A pharmaceutical composition for treatment and/or prevention of liver cancer contains as an active ingredient an...
9416191 Pharmaceutical composition for treatment and/or prevention of cancer  
According to the present invention, a cancer antigen protein to be specifically expressed on the surfaces of cancer cells is identified and thus the use of an antibody targeting the cancer antigen...
9416176 RBM3 protein in colorectal cancer prognostics  
The present invention provides means, such as a method, for determining whether a mammalian subject having a colorectal cancer belongs to a first or a second group, wherein the prognosis of...
9416125 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Substituted cycloalkenopyrazoles as BUB1 inhibitors for the treatment of cancer
 
Compounds of formula (I), processes for their production and their use as Bub1 kinase inhibitors for the treatment of hyperproliferative diseases and/or disorders responsive to induction of cell...
9416123 Kinase modulators for the treatment of cancer  
Compounds of the substituted pyrazole class as treatments for cancer are reported. A method of treating cancer in which a compound that inhibits the activity of receptor kinases. Said method is...
9416101 Methods and compositions useful in treating cancer and reducing WNT mediated effects in a cell  
Provided herein are novel compounds, pharmaceutical compositions for use, inter alia, in methods of reducing Wnt-mediated effects and treating cancer.
9415238 Pharmaceutical kit and methods for cancer treatment via intracavity delivery and for preparing metal nanoparticle-antibody fragment conjugate  
The present invention provides a pharmaceutical kit, methods for cancer treatment and for preparing a metal nanoparticle-antibody fragment conjugate, which can reduce the recurrence rate of cancer...
9415122 Methods and compositions for the detection of cancer cells  
A molecular probe for use in detecting, monitoring, and/or imaging cancer cells and/or cancer cell metastasis, migration, dispersal, and/or invasion includes a targeting agent and a detectable...
9415103 Combination therapy to prevent DCIS formation and progression to breast cancer  
A method of treating a ductal carcinoma in situ (DCIS) lesion in a subject in need thereof is disclosed. The method comprises administering to the subject a therapeutically effective amount of a...
9415098 DNA vaccine for use in pancreatic cancer patients  
The present invention relates to an attenuated mutant strain of Salmonella comprising a recombinant DNA molecule encoding a VEGF receptor protein. In particular, the present invention relate to...
9415088 Use of AGR3 for treating cancer  
Embodiments are related to processes for using an Anterior Gradient Homolog 3 (AGR3) therapeutic to treat an enhanced AGR2 expressing cancer, or its premalignant precursor, comprising...
9415085 Method of treating prostate cancer with GnRH antagonist  
The invention provides methods and dosing regimens for safely and effectively treating androgen-dependent prostate cancer with a gonadotrophin releasing hormone (GnRH) antagonist without causing a...
9415078 Method of treating desmocollin-3 expressing cancer with Mycobacterium w  
The present invention relates to increase in survival of mammals suffering from desmocollin 3 expressing cancers. Mycobacterium w is administered to mammals suffering from desmocollin-3 expressing...
9415050 Methods for the treatment of HER2 amplified cancer  
Described herein are methods and compositions for treating HER2-amplified cancer. The methods include administering to an individual in need thereof ibrutinib.
9415011 Method for treatment of liver cancer and inhibition of metastasis with CXC-chemokine-receptor 4-targeted nanoparticle  
Provided is a method for treatment of liver cancer and inhibition of metastasis with CXCR4-targeted nanoparticle. A CXCR4 antagonist is used as a targeting molecule to modify a lipid carrier for...
9410956 Micro-RNA profiling in ovarian cancer  
MicroRNAs (miRNAs) represent a novel class of genes that function as negative regulators of gene expression and have recently been implicated in several cancers. However, aberrant miRNA expression...
9410954 Human papilloma virus as predictor of cancer prognosis  
Methods of treating a head and neck cancer are disclosed.
9410949 Label-free detection of renal cancer  
Natural and/or synthetic antibodies for specific proteins are adhered to nanoparticles. The nanoparticles are adhered to a substrate and the substrate is exposed to a sample that may contain the...
9410944 Methods of assaying sensitivity of cancer stem cells to therapeutic modalities  
The present invention is directed to methods of measuring the proliferative ability of individual patient cancer stem cells. The present invention provides a method for treating a cancer patient...
9410207 Method and compositions for detecting epidermal growth factor receptor variant forms in cancer cells  
Method and compositions for screening for the presence of Epidermal Growth Factor Receptor variant 3 (EGFR(v3)) in a sample are described. The method comprises obtaining a sample containing a...
9410206 Long noncoding RNA (lncRNA) as a biomarker and therapeutic marker in cancer  
Long noncoding RNAs (lncRNAs) that may be used as cancer biomarkers and methods of diagnosing, prognosing and monitoring cancer including, but not limited to, cutaneous melanoma using said lncRNAs...
9410188 Method and kit for discriminating between breast cancer and benign breast disease  
A method and kit are related to discriminating between breast cancer and benign breast disease by the determination of the expression level of at least one target gene including a nucleic acid...
9409993 Pharmaceutical composition for treatment and/or prevention of pancreatic cancer  
This invention relates to a pharmaceutical composition for treatment and/or prevention of pancreatic cancer, comprising as an active ingredient an antibody or a fragment thereof which has...
9409987 Polypeptides and polynucleotides, and uses thereof for treatment of immune related disorders and cancer  
This invention relates to LY6G6F, VSIG10, TMEM25 and LSR proteins, which are suitable targets for immunotherapy, treatment of cancer, infectious disorders, and/or immune related disorders, and...
9408888 High affinity bivalent helically constrained peptide against cancer  
The present invention describes a novel bivalent helically constrained peptide targeted against S100B that is an effective anti-cancer drug against cancers that over-express S100B. This helix...
9408887 Intermittent dosing regimen for treating breast cancer  
Diagnostic and therapeutic methods pertaining to diseases and disorders of the breast, uterus and ovary are encompassed herein. More particularly, diagnostic methods for early detection of...
9408859 Pharmaceutical compositions useful for preventing and treating cancer  
Disclosed is a method of treating a cancer on a mammal, comprising administering to the mammal in need thereof a therapeutically effective amount of a compound
9408853 Iridium/rhodium anti-cancer compounds  
The present invention relates to novel iridium and/or rhodium containing complexes for use as a cytotoxic, such as an anti-cancer agent. There is also provided a method of preparing said compounds.
9408848 Fluorescent CDK inhibitors for treatment of cancer  
Disclosed are molecules and their synthesis. The fluorescent moiety also facilitates screening, tracking, and pharmacodynamic studies of the drug in a biological system both in vitro and in vivo.
9408811 Pharmaceutical composition comprising guttiferone F for the treatment of prostate cancer  
Prostate cancer is the most commonly diagnosed cancer in males and one of the leading causes of cancer death. Although treatment options have increased for some patients, overall progress has been...
9404927 Systems and methods for diagnosing and treating cancer  
Embodiments of the invention provide a method detecting and treating cancer, such as lung cancer. In some aspects, the method may include detecting cancer in a subject, which may comprise...
9404926 Immune gene signatures in cancer  
This invention relates to methods for selecting a treatment, treating, and predicting survival time in subjects with cancer, such as colorectal cancer, based on tumor expression levels of...
9404925 Cancer antigen and use thereof  
An object of the present invention to provide: a human pancreatic cancer antigen and/or a human colon cancer antigen that can be applied to the diagnosis and/or treatment of various types of...
9403911 Compositions and methods for detection and treatment of cancer  
Novel antibodies for the detection and/or treatment of a cancer (e.g., a pancreatic cancer or an ovarian cancer) are provided. In certain embodiments the antibodies bind a region of the MUC4...
9403889 Diagnostic lung cancer panel and methods for its use  
Disclosed herein are novel diagnostic lung cancer panels and the use of these panels to diagnose, predict, and characterize lung cancer and to monitor or predict treatment efficacy.
9403877 Peptide agents for cancer therapy  
There is provided peptides for inhibiting growth of cancer cells, the peptides comprising the amino acid sequence RxKxKxxxxR wherein K and R are respectively lysine and arginine amino acid...
9403822 Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases  
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic...