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8465917 Methods for determining heptocellular carcinoma subtype and detecting hepatic cancer stem cells  
The invention provides a method of determining an HCC subtype in a subject comprising a) obtaining a sample from the subject, b) assaying the sample to detect the expression of 1 or more...
8465916 Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments  
The present invention is directed to a method for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) treatment. In a preferred embodiment, the presence of at...
8465756 Immunogenic peptides of tumor associated antigen L6 and uses thereof in cancer therapy  
An immunopeptide containing a T cell epitope from the tumor associated antigen L6 (TAL6) and a nucleic acid encoding the immunopeptide are described herein. The immunopeptide or its encoding...
8465743 Anti-vascular endothelial growth factor receptor-2 chimeric antigen receptors and use of same for the treatment of cancer  
The invention provides chimeric antigen receptors (CARs) comprising an antigen binding domain of a KDR-1121 or DC101 antibody, an extracellular hinge domain, a T cell receptor transmembrane domain,...
8465738 Use of vascular endothelial growth factor receptor 1+ cells in treating and monitoring cancer and in screening for chemotherapeutics  
The present invention is directed to a method of inhibiting tumor formation in a cancer patient at a site remote from sites of prior tumor formation and to a method of preventing metastases. These...
8465533 Treating cancer using electromagnetic fields in combination with photodynamic therapy  
A light generating circuit is implanted in a subject's body and aimed at a target region such as a tumor. A photosensitizer is introduced into the target region, and an AC electric field is induced...
8461158 Pyrimidinyl and 1,3,5-triazinyl benzimidazole sulfonamides and their use in cancer therapy  
Provided herein are pyrimidinyl and 1,3,5-triazinyl benzimidazole sulfonamides, e.g., compounds of Formulae IA, IB, and IC, and their pharmaceutical compositions, preparation, and use as agents or...
8461136 Compositions and methods for protecting cells during cancer chemotherapy and radiotherapy  
Compositions, pharmaceutical preparations and methods are disclosed for protecting non-neoplastic cells from damage caused by cancer chemotherapeutic agents or radiation therapy, during the course...
8461124 Five- and six-membered conformationally locked 2′,4′-carbocyclic ribo-thymidines for the treatment of infections and cancer  
Conformationally locked 2′,4′-carbocylic nucleosides with improved thermal and nuclease stability are disclosed. Oligonucleotides incorporating the locked nucleosides, and methods of treating dis...
8461118 Lytic peptides having anti-proliferative activity against prostate cancer cells  
Lytic peptides, including fusion peptides of lytic peptides conjugated with luteinizing hormone-releasing hormone or modified versions thereof to target luteinizing hormone-releasing hormone...
8461101 Targeting PAX2 for the treatment of breast cancer  
The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of...
8460882 Cancer biomarkers  
Provided is a biomarker for detecting cancer, in particular prostate cancer in a male subject, the biomarker comprising at least one homeodomain containing transcription factor, such as a HOX...
8460881 Nucleic acids and corresponding proteins entitled 254P1D6B useful in treatment and detection of cancer  
A novel gene 254P1D6B and its encoded protein, and variants thereof, are described wherein 254P1D6B exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the...
8460873 Pancreatic cancer genes  
The present invention provides the art with the DNA coding sequences of polynucleotides that are up-or-down-regulated in cancer and dysplasia. These polynucleotides and encoded proteins or...
8460658 Method of treating cancer and/or cellular proliferative conditions and agents targeting hyaluronan anabolism useful for same  
The present invention relates generally to the modulation of hyaluronan (HA) synthesis and degradation. The present invention further contemplates modulation of cellular proliferation, useful in...
8455624 Methods and compositions for detecting endometrial or ovarian cancer  
Some embodiments of the present invention relate to methods and compositions for assessing the absence, presence, progression, or stage of cancer. In particular, methods and compositions for...
8455623 Compositions and methods for diagnosing and treating cancer  
Isolated antibodies that specifically bind the human MET Receptor and inhibit MET signaling are described. Also described are methods of treating cancer, the methods comprising administering a...
8455615 Methods and compositions for prostate cancer immunotherapy  
The present invention features methods and compositions (e.g., immune response stimulating peptides (e.g., ERG or SIM2 peptides), activated immune cells, antigen-presenting cells, and antibodies or...
8455200 Measurement of PKA for cancer detection  
The present invention relates to a method of detecting the presence of cancer by measuring the level of enzyme activity and autoantibodies in the blood of an individual. In particular the present...
8455029 Method for reducing cancer stimulating compounds in cow's milk  
A decrease in the biological activity of the proteins and hormones present in milk, which have been implicated in certain cancers, is accomplished by exposing the hormones and proteins to...
8450283 Composition for treating cancer and use thereof  
The present invention provides a cyclic peptide containing RRXR motif. The present invention also provides a composition comprising the said cyclic peptide and a pharmaceutical acceptable carrier....
8450062 SOCS-3 promoter methylation in cancer  
This invention provides compositions and methods for the diagnosis and treatment of cancers that exhibit decreased SOCS-3 expression.
8449929 Herbal medicinal composition and extract thereof for inhibiting growth of cancer cells  
The present invention relates to herbal medicinal compositions and extracts thereof for inhibiting growth of cancer cells. One of the examples described in the present invention comprises...
8449441 Methods to arrest cancer cell growth and proliferation using electromagnetic energy delivered via electromagnetic coil systems  
A non-invasive method of using electromagnetic field energies to reduce or arrest the growth rate and proliferation of cancer cells, and induce apoptosis in cancer cells, relatively without...
8447379 Detection, measurement, and imaging of cells such as cancer and other biologic substances using targeted nanoparticles and magnetic properties thereof  
The present invention can provide a method of determining the presence, location, quantity, or a combination thereof, of a biological substance, comprising: (a) exposing a sample to a plurality of...
8445722 Method for screening anti-cancer compounds inhibiting function of TM4SF5 and anti-cancer composition containing chalcone compounds  
The present invention relates to a method for screening an anticancer compound and an anticancer compound screened using the method, and more particularly, to a method for screening an anticancer...
8445638 Use of a truncated eIF-5A1 polynucleotide to induce apoptosis in cancer cells  
The present invention relates to the combinatorial use of an siRNA targeted against an endogenous gene to knock out or knock down expression of the endogenous gene in a host and a delivery of a...
8445537 Compounds that inhibit human DNA ligases and methods of treating cancer  
Methods for treating cancer using compounds that inhibit human DNA ligases. Methods for using compounds that inhibit human DNA ligases to provide insights into the reaction mechanisms of human DNA...
8445507 Androgen receptor modulator for the treatment of prostate cancer and androgen receptor-associated diseases  
A hydantoin compound useful for the prevention or treatment of hyperproliferative diseases or disorders.
8445492 Method for inhibiting growth of cancer cells and cell telomere and diseases of cell proliferation by using heteroannelated anthraquinone derivative compounds  
A heteroannelated anthraquinone derivative compound is provided. The heteroannelated anthraquinone derivative compound is represented by a formula (I): wherein R1 is a substituent being one...
8445442 CCL18 and CCL3 methods and compositions for detecting and treating cancer  
The invention relates to methods of treating cancer by administering one or more chemokines that are downregulated in cancerous cells. More specifically, the invention provides methods for treating...
8445268 Her-2/neu DNA vaccine having anti-cancer activity  
The present invention relates to human Her-2/neu expressing plasmid constructs having anti-cancer activity and a DNA vaccine comprising same for preventing and/or treating cancer. The Her-2/neu DNA...
8445211 I-Plastin assay method for the in vitro diagnosis of colorectal cancer  
A method for the in vitro diagnosis of colorectal cancer by determining the presence of the I-Plastin tumor marker in a biological sample taken from a patient suspected of having colorectal cancer....
8445202 Method of detecting colon cancer marker  
It is intended to provide a non-invasive and convenient method of detecting a tumor marker for diagnosing colon cancer which is superior in sensitivity and specificity to the existing fecal occult...
8444988 Cancer treatment method  
A method of treating cancer is described including administration of a 4-quinazolineamine and at least one other anti-neoplastic agent as well as a pharmaceutical combination including the...
8444983 Composition of anti-ENDO180 antibodies and methods of use for the treatment of cancer and fibrotic diseases  
The present invention provides antibodies or antigen-binding fragments thereof that specifically bind the ENDO180 polypeptide and are internalized thereby, to conjugates comprising the molecules,...
8444974 Use of antibodies for the vaccination against cancer  
Described is the use of antibodies which are directed against human cellular membrane antigens for the vaccination against cancer diseases.
8444965 Tumor cells from immune privileged sites as base cells for cell-based cancer vaccines  
The present invention relates to tumor cell-based vaccines and methods of using same, wherein the vaccines are based on naturally immune privileged tumor cells that have been genetically modified...
8442629 Iontophoresis preparation for treating breast cancer and/or mastitis  
Provided is to enhance the therapeutic effect of an iontophoretic preparation for treatment of breast cancer or mastitis. An iontophoretic preparation for treatment of breast cancer and/or mastitis...
8440798 Generation of a cancer-specific immune response toward MUC1 and cancer specific MUC1 antibodies  
The present invention provides a method for inducing a cancer specific immune response against MUC1 using an immunogenic glycopeptide. Other aspects of the invention are a pharmaceutical...
8440714 Acid-labile lipophilic prodrugs of cancer chemotherapeutic agents  
The present application discloses an acid labile lipophilic molecular conjugate of cancer chemotherapeutic agents and methods for reducing or substantially eliminating the side effects of...
8440410 Reagents and methods for use in cancer diagnosis, classification and therapy  
Methods and reagents for classifying tumors and for identifying new tumor classes and subclasses. Methods for correlating tumor class or subclass with therapeutic regimen or outcome, for...
8440409 Protein C inhibitor as a biomarker for prostate cancer  
The present invention provides a protein-based biomarker, Protein C Inhibitor (PCI) that is useful in qualifying prostate cancer status in a patient. In particular, the biomarker of this invention...
8440407 Gene expression profiles to predict relapse of prostate cancer  
The present disclosure provides a method for cancer relapse prediction that provides higher resolution grading than Gleason score alone. In particular, the method provides for prediction of...
8440402 Gene detection assay for improving the likelihood of an effective response to a HER2 antibody cancer therapy  
The invention provides a method for more effective treatment of patients susceptible to or diagnosed with tumors overexpressing HER2, as determined by a gene amplification assay, with a HER2...
8440396 Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer  
This invention relates to the use of tumor-derived or associated extracellular ribonucleic acid (RNA) found circulating in the plasma or serum fraction of blood for the detection, monitoring, or...
8440184 Compositions of engineered human arginases and methods for treating cancer  
Compositions and methods for the treatment of cancer are described, and, more preferably, to the treatment of cancers that do not express, or are otherwise deficient in, argininosuccinate...
8440180 Anti-cancer composition comprising aquatic microbial extract  
There is provided an anti-cancer composition comprising an aquatic microbial extract, and there is more particularly provided an anti-cancer composition comprising a Bacillus sp. strain extract.
8436327 Multi-field charged particle cancer therapy method and apparatus  
The invention relates to treatment of solid cancers. More particularly, the invention relates to a combined rotation/raster method, referred to as multi-field charged particle cancer therapy. The...
8436145 Compositions and methods for diagnosing and treating cancer and neurodegenerative diseases related to Beclin-1  
The present invention relates to antibodies specific for human Beclin-1 protein phosphorylated at position Thr 119 and uses thereof. In particular, these antibodies are useful in diagnosing...