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9006184 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Cancer vaccine composition
 
A cancer vaccine composition for human leukocyte antigen (HLA)-A*0206-positive persons, comprising a protein product of the tumor suppressor gene WT1 or a partial peptide thereof.
9006173 Microcystins as agents for treatment of cancer  
This invention relates to the use of microcystins as agents for treatment of cancer. Also provided are methods of screening for microcystins with improved cytotoxicity.
9005678 Pharmaceutical composition for treating cancer and use thereof  
The present invention discloses a pharmaceutical composition for treating cancer, comprising: (1) a herbal composition generated from Astragali membranaceus radix, Cinnamomi cortex, Paeonia alba...
9005670 Use of histone acetyltransferase inhibitors as novel anti-cancer therapies  
The present invention provides methods for treating cancer comprising inhibiting the activity of p300/CBP histone acetyltransferase (HAT). Also provided are p300/CBP HAT inhibitors for treating a...
9005629 Method for treating cancer with an antibody to CD223 protein  
Mammals with cancer are treated with an antibody which specifically binds to CD223 protein and inhibits negative T cell regulatory function of CD223. The mammal may be a human. The antibody may be...
9005613 Anti-mucin antibodies for early detection and treatment of pancreatic cancer  
Described herein are compositions and methods of use of anti-pancreatic cancer antibodies or fragments thereof, such as murine, chimeric, humanized or human PAM4 antibodies. The antibodies show...
9005600 Compounds useful for multi-level specific targeting of cancer cells  
A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13Rα2 binding ligand; at least one effector molecule (e.g., one, two, three or more...
9002653 Methods for assembling panels of cancer cell lines for use in testing the efficacy of one or more pharmaceutical compositions  
The present invention relates to algorithms for use in defining genomic subgroups of tumors and cancer cell lines. The present invention also relates to methods for assembling panels of tumors and...
9000139 Composition for preventing or treating cervical cancer having human papillomavirus plasmodium and immunity enhancer  
A composition for preventing or treating cervical cancer comprising a human papillomavirus plasmodium and an immunity enhancer is provided. A fusion protein including a fusion polypeptide...
9000031 Thioxanthone-based autophagy inhibitor therapies to treat cancer  
The present specification provides compositions comprising a thioxanthone-based autophagy inhibitor and/or a cancer therapeutic autophagy inducing compound, pharmaceutical kits comprising these...
8999968 Kinase inhibitors and method of treating cancer with same  
The invention is directed to a compound represented by the following structural formula and pharmaceutically acceptable salts thereof: Compounds represented by this structural formula are kinase...
8999657 Reagents, methods, and kits for the classification of cancer  
Reagents, methods, and kits for the classification of cancer that comprise or employ antibodies that bind specific regions of CD43. One method includes contacting tissue with an antibody capable...
8999656 PODXL protein in colorectal cancer  
The present disclosure provides a method for determining whether a mammalian subject having a colorectal cancer belongs to a first or a second group, wherein the prognosis of subjects of the first...
8999396 Breast cancer therapy based on hormone receptor status with nanoparticles comprising taxane  
The present invention relates to methods and kits for the treatment of breast cancer based on hormone receptor status of progesterone receptor and estrogen receptor comprising the administration...
8999296 Method of detecting bladder cancer  
Provided is a sensitizing detection agent of an oral or intravenous administration type which enables the detection of bladder cancer with a higher sensitivity without causing pain to the patient....
8995736 System and method for prostate visualization and cancer detection  
A method, system, and computer-readable medium for detecting a disease of a prostate. Exemplary embodiments of the present disclosure can include receiving an image dataset acquired with at least...
8995608 Compact microbeam radiation therapy systems and methods for cancer treatment and research  
The present subject matter relates to compact, non-synchrotron microbeam radiation therapy (MRT) systems and methods for cancer research and treatment based on a carbon nanotube distributed x-ray...
8993612 Modulators of calcium release-activated calcium channel and methods for treatment of non-small cell lung cancer  
Disclosed are novel calcium release-activated calcium (CRAC) channel inhibitors, methods for preparing them, pharmaceutical compositions containing them, and methods of treatment using them. The...
8993587 Combination of syrosingopine and mitochondrial inhibitors for the treatment of cancer and immunosuppression  
The invention relates to a combination of syrosingopine and a mitochondrial inhibitor, e.g. metformin or oligomycin, and the use of the combination of syrosingopine and a mitochondrial inhibitor...
8993333 Method of evaluating cancer risk in human  
Disclosed is a method of providing a risk evaluation and diagnosis of human cancer, by examining the presence, in the volatile fraction of a human saliva sample, of a combination of particulate...
8993278 Conjugates for cancer therapy and diagnosis  
The present invention relates to conjugates of a drug and an amino acid or an amino acid derivative or analog, pharmaceutical compositions that include the conjugates and methods of use thereof....
8993227 Cancer prognosis by determining phosphorylation of a Xom polypeptide  
Disclosed are composition and methods for treating development-related disorders. Also disclosed are diagnosis methods, prognosis methods, and drug screening methods.
8992990 Magnetic nanocomposite for inhibiting/treating cancer and method for fabricating the same  
The present invention discloses a magnetic nanocomposite for inhibiting/treating cancer and a method for fabricating the same. The magnetic nanocomposite comprises a core formed of a plurality of...
8992984 Protocells and their use for targeted delivery of multicomponent cargos to cancer cells  
Various embodiments provide materials and methods for synthesizing protocells for use in targeted delivery of cargo components to cancer cells. In one embodiment, the lipid bilayer can be fused to...
8992958 Ultrasonic cancer treatment enhancer and cell killer  
There is provided an ultrasonic cancer treatment enhancer and cell killer that can significantly improve the effect of treating cancer by ultrasonic irradiation while ensuring a high level of...
8992947 Method for predicting therapeutic effect of chemotherapy on renal cell cancer  
The present invention developed a novel antitumor agent for renal cell carcinoma that cannot be fully treated by the existing therapies. The present invention provides an antitumor agent...
8992931 Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy  
Described herein are compositions and methods of use of radionuclide-antibody conjugates (for RAIT) and drug-antibody conjugates (ADC). The combination of RAIT and ADC was more efficacious than...
8992231 Prostate phantom, system for planning a focal therapy of a prostate cancer comprising such prostate phantom and method for planning a focal therapy of a prostate cancer implementing such system  
Prostate phantom comprising an artificial prostate (1) and an artificial lesion arranged within the artificial prostate (1), wherein the artificial prostate (1) comprises: a first part (1a)...
8987425 Pharmaceutical composition for preventing or treating cancer  
The invention provides a fusion protein comprising (a) a first protein comprising a polypeptide which specifically binds to Annexin A1 and (b) a second protein comprising a polypeptide which...
8987316 Isocyanate and isothiocyanate compounds for cancer treatment  
The present invention relates to novel isocyanate and isothiocyanate compounds, to pharmaceutical compositions comprising them, and to the use thereof in the treatment of cancer diseases in humans...
8987281 Methods of treating cancer  
Described are methods and compositions for treating epithelial tumors with a folate-vinca conjugate in combination with at least one other chemotherapeutic agent in which the tumors include...
8987240 Pharmaceutical compositions comprising estetrol derivatives for use in cancer therapy  
The present invention relates to a method of treating or preventing estrogen-suppressed tumors in a mammal, said method comprising the administration of a therapeutically effective amount of an...
8987224 MicroRNA-198 as a tumor suppressor in pancreatic cancer  
A novel network of tumorigenic prognostic factors is identified that plays a critical role in advanced pancreatic cancer (PC) pathogenesis. This interactome is interconnected through a central...
8986701 Enzyme prodrug cancer therapy selectively targeted to tumor vasculature and methods of production and use thereof  
Methods of treating cancer by targeting tumor vasculature using an enzyme prodrug cancer therapy treatment are provided.
8986687 Compounds inhibiting CD95 signaling for the treatment of pancreatic cancer  
The present invention is concerned with compounds inhibiting CD95 signaling in pancreatic cancer cells. Furthermore, contemplated by the current invention are medicaments comprising such a...
8986674 Methods and compositions concerning poxviruses and cancer  
The present invention concerns methods and compositions for the treatment of cancer and cancer cells using altered poxviruses, including a vaccinia virus that has been altered to generate a more...
8986672 Use of mutant Herpes Simplex Virus-2 for cancer therapy  
The present invention is directed to the composition and use of a modified Herpes Simplex Virus Type 2 (HSV-2) as a medicament in the treatment of cancer. The modified HSV-2 has fusogenic...
8981075 PSA binding aptamer and method for diagnosis of prostate cancer  
The present invention provides an aptamer that binds to prostate-specific antigen (PSA), the aptamer including: a preceding region having a random polynucleotide sequence consisting of from 1 to...
8980934 Kinase inhibitors and method of treating cancer with same  
The present teachings provide a compound represented by structural formula (I): or a pharmaceutically acceptable salt thereof. Also described are pharmaceutical compositions and methods of use...
8980933 Combretastatin analogs for use in the treatment of cancer  
The present invention relates to specific analogs of combretastatin, in particular the compounds of formula (I) as described and defined herein, and pharmaceutical compositions comprising the...
8980932 Cancer targeting using carbonic anhydrase isoform IX inhibitors  
The present invention concerns novel carbonic anhydrase IX inhibitors comprising a nitroimidazole moiety and their use in therapy of hypoxic conditions, in particular cancer treatment, especially...
8980638 Use of IMP3 as a prognostic marker for cancer  
Provided herein are methods and compositions for the prognostic evaluation of a patient suspected of having, or having, cancer by assessing the expression of IMP3 in a biological sample of a...
8980637 Breast cancer biomarkers and identification methods using NMR and gas chromatography-mass spectrometry  
A method for the parallel identification of one or more metabolite species within a biological sample is provided. The method comprises producing a first spectrum by subjecting the sample to a...
8980573 Method for providing diagnosis of cancer using seprase as a marker  
The present invention relates to a method aiding in the assessment of cancer. It discloses the use of the human fibroblast activation protein (FAP/seprase) as a universal marker of different...
8980571 Method of identifying a candidate compound which may inhibit α9-nAchR overexpression or estrogen receptor-dependent transcription in nicotine-derived-compound-induced breast cancer cells  
The invention relates to methods of identifying a candidate compound which may inhibit estrogen receptor-dependent transcription or α9-nAChR overexpression and proliferation of...
8980570 Composition for cancer prognosis prediction comprising anti-TMAP/CKAP2 antibodies  
The present invention relates to an antibody which specifically binds to TMAP (tumor associated microtubule associated protein)/CKAP2 (cytoskeleton associated protein 2) or a fragment thereof, and...
8980557 Marker for determination of sensitivity to triplet combination anti-cancer agent  
To provide a marker for determining sensitivity of a patient to an anti-cancer agent, which marker can determine whether or not the patient has a therapeutic response to the anti-cancer agent, and...
8980554 Genetic make-up modifies cancer outcome  
A frequent SNP A259G (K87E) genotype switch in the MMP8 gene in has been found to modify the clinical behavior of cancers. The modification varies based on the patient's genotype for the SNP, and...
8980269 G-protein coupled receptor-associated sorting protein 1 as a cancer biomarker  
A method for determining whether early stage cancer is present in a subject comprises detecting the expression level of GASP-1 in the subject by detecting the amount of GASP-1 peptide fragments...
8980268 Methods for treating cancer by administering an anti-Ang-2 antibody  
The present invention provides antibodies that bind to angiopoietin-2 (Ang-2) and methods of using same. According to certain embodiments of the invention, the antibodies are fully human...