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9089556 Method for treating cancer using an antibody that inhibits notch4 signaling  
The invention provides methods for treating cancer via administering to a patient having a solid tumor a therapeutically effective amount of an antibody against Delta-like ligand 4(Dll4) or other...
9089540 Method for determination of sensitivity to anti-cancer agent  
Provided are an marker for determining sensitivity to an anticancer agent capable of distinguishing a therapeutic response of an individual patient and a novel means for a cancer therapy using the...
9089513 De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy  
The present invention generally provides compositions methods and composition relating to the diagnosis and/or treatment of cancers having a cell surface de-N-acetylated sialic acid antigen, e.g.,...
9086414 Phosphorylated C-ErbB2 as a superior predictive theranostic marker for the diagnosis and treatment of cancer  
The present invention provides reliable methods to identify subsets of subjects with a cancer of epithelial origin characterized by a high level of phosphorylated c-erbB2 which does not correlate...
9086412 Extracellular vesicle-associated protein markers of cancer  
Extracellular vesicle-associated protein biomarkers for use in diagnosing and staging carcinomas, e.g., lung and ovarian cancers.
9085772 Method for suppressing receptor tyrosine kinase-mediated pro-survival signaling in cancer cell  
In order to provide a screening method for a compound capable of suppressing a mechanism of ROR1 by targeting ROR1 and to provide a drug comprising as an active ingredient a compound capable of...
9085539 Cyclic N,N′-diarylthiourea—androgen receptor antagonist, anti breast cancer composition and use thereof  
The present invention relates to novel cyclic N,N′-diarylurea—androgen receptor antagonist, anti-cancer agent, pharmaceutical composition, medicament, and method for treatment of breast cancer...
9084812 Composition useful for the prevention or reduction of the progression of prostate cancer  
It is described a composition comprising as active ingredients green tea extract and pomegranate extract for the prevention or reduction of the progression of prostate cancer.
9084790 Compositions and methods for treating skin cancer associated diseases  
The invention provides compositions and methods for treating skin cancer associated diseases. Specifically, the invention relates to topically administering a signaling pathway inhibitor or a...
9084776 Methods for treating cancer using anti-PD-1 antibodies  
The present invention provides isolated monoclonal antibodies, particularly human monoclonal antibodies, that specifically bind to PD-1 with high affinity. Nucleic acid molecules encoding the...
9084775 Methods for diagnosing and treating neuroendocrine cancer  
The present invention relates to a method for diagnosing neuroendocrine cancers via detecting the presence of N-methyl D-asparate-associated (NMDA) glutamate receptors type 1 and/or type 2....
9084771 Methods and compositions for treating cancer  
This disclosure provides compositions and method useful for treating cell proliferative disorders including cancer. The disclosure provides cannabidiol derivatives and compositions thereof either...
9084770 Modulation of insulin like growth factor I receptor expression in cancer  
Provided herein are methods, compounds, and compositions for reducing expression of an IGF-IR mRNA and protein in an animal. Also provided herein are methods, compounds, and compositions that...
9084766 Compounds and compositions for targeting cancer stem cells  
The invention provides naphthofuran compounds, polymorphs of naphthofuran compounds, naphthofuran compounds in particle form, purified compositions that contain one or more naphthofuran compounds,...
D734483 Tissue cell block for cancer detection  
9081998 Method for utilizing soft X-ray microimaging for cancer cell image recognition  
This invention discloses a method for utilizing soft X-ray microimaging for cancer cell image recognition. The method comprises the steps of 1) sample preparation; 2) pathological examination; 3)...
9081878 Bio-medical unit and applications for cancer treatment  
An in vivo cancer treatment system includes a plurality of bio-medical units, a communication control device, and a wireless power source device. A bio-medical unit of the plurality of bio-medical...
9081013 Marker for detecting gastric cancer and method for detecting gastric cancer  
It is intended to provide a method for detecting gastric cancer, which is low invasive to a human test subject and has high detection sensitivity and accuracy. The present invention provides a...
9080216 Genetic changes in ATM and ATR/CHEK1 as prognostic indicators in cancer  
The present invention relates to the discovery that, in human cancer, an 11q deletion of ATM together with an increase in ATR and CHEK1 expression correlates with resistance to ionizing radiation...
9080215 MicroRNAs differentially expressed in cervical cancer and uses thereof  
The present invention concerns methods and compositions for identifying a miRNA profile for a particular condition, such as cervical disease, and using the profile in assessing the condition of a...
9080203 Method and system for automated image analysis in cancer cells  
A method of screening for the presence and/or extent of a pathology in a subject, the pathology characterized by an abnormal chromosomal component in a cell of the subject, comprising the steps...
9080173 Methods and compositions for RNAi-based cancer treatment  
The present invention generally concerns methods and compositions for treating mutated K-ras expressing cancers.
9080154 Cancer stem cell survivor lines  
A method of determining the relative effectiveness of potential chemotherapeutic agents designed to inhibit neoplasm, growth or metastasis is described. The chemotherapeutic agent may be curcumin....
9079957 Diagnosis and treatment of cancer using anti-TMPRSS11E antibody  
[Problem to be Solved] An object of the present invention is to provide novel means for the treatment and diagnosis of cancer.[Solution]The present inventors have obtained a monoclonal antibody...
9078901 Pharmacological modulation of telomere length in cancer cells for prevention and treatment of cancer  
Acyclic nucleoside analogs such as acyclovir, ganciclovir, penciclovir and the corresponding pro-drugs, i.e., valacyclovir, valganciclovir and famciclovir, respectively have been identified as...
9078895 Method for treating ocular cancer  
It has now been found that the p53 pathway is inactivated in ocular cancers such as retinoblastoma. As such, the present invention is a method for inducing ocular cancer cell death using a p53...
9078856 Improving efficacy of cancer therapy  
Embodiments of the invention provide a method of improving the efficacy of an anti-cancer therapy and a method of treatment of cancer by normalizing angiogenesis in cancer. By enhancing the cell...
9075071 Methods for diagnosis and treatment of cancer  
Methods for diagnosis and treatment of a cancer treatable with a c-Abl inhibitor are provided. Methods for diagnosing a cancer treatable with a c-Abl inhibitor include providing a biological...
9075067 Marker for the diagnosis of cancer  
The present invention relates to a method for diagnosing peritoneal carcinoses or metastatic primary tumors in a subject, as well as to a method for providing a prognosis to a subject diagnosed...
9075066 CST1, DCC1, IFITM1 or MELK as markers for diagnosing stomach cancer  
The present invention relates to a biomarker for gastric cancer, CST1 (cysteine proteinase inhibitor, type 2 family), DCC1 (Defective in sister chromatid cohesion homolog 1), IFITM1 (interferon...
9075065 Prostate cancer biomarker  
The present invention relates to the field of prostate cancer. Particularly the invention relates to villin as a novel prostate biomarker. The invention further relates to compositions comprising...
9075064 Method for decreasing radioresistance and growth, metastasis and infiltration of cancer cells through regulating expression or activity of TM4SF4 in non-small cell lung cancer  
The present invention relates to a pharmaceutical composition or an anticancer agent for preventing and treating non-small cell lung cancer, containing a substance for regulating the expression or...
9075063 Methylation analysis to determine the presence of cancer cells  
The present invention relates to a method for determination of the presence or absence of cancer cells in a biological sample or a method for determination of the prognosis of a colorectal cancer...
9075061 Method for determining the estrogen receptor status of breast cancer  
The present invention relates to a method for determining the estrogen receptor status of patients suffering from breast cancer. The present invention also aims to provide methods and devices for...
9075060 Methods for diagnosing oral or oral-pharyngeal cancer  
A method of diagnosing oral cancer or oral pharyngeal cancer in a subject in need thereof is provided. The method comprising determining a level or activity of at least one marker in a saliva...
9075059 Compositions and methods for detecting plectin-1 as a biomarker for cancer  
The present invention provides compositions and methods useful for diagnostic and imaging techniques for detecting and localizing the biomarker Plectin-1. The present invention provides multimeric...
9074253 Methods for diagnosis, prognosis and treatment of primary and metastatic basal-like breast cancer and other cancer types  
In one embodiment, a method of theranostic classification of a breast cancer tumor is provided, comprising obtaining a breast cancer tumor sample from a subject, detecting an expression level of...
9074206 Compositions and methods for micro-RNA expression profiling of colorectal cancer  
The present invention relates compositions and methods for microRNA (miRNA) expression profiling of colorectal cancer. In particular, the invention relates to a diagnostic kit of molecular markers...
9073995 Bladder cancer tumor marker, antibody and use thereof  
Provided in the present invention are an aberrantly glycosylated integrin, AG-α3β1, and use thereof as a bladder cancer marker. Also provided in the present invention are a hybridoma cell...
9073917 Anti-cancer compound and pharmaceutical composition containing the same  
The invention relates to a compound of formula (I), more specifically in the levorotatory form (1a) thereof, in particular the form having a rotatory power [α]D=−38.6+0.7 at a concentration of...
9073896 Compounds that inhibit human DNA ligases and methods of treating cancer  
Methods for treating cancer using compounds that inhibit human DNA ligases. Methods for using compounds that inhibit human DNA ligases to provide insights into the reaction mechanisms of human DNA...
9073880 2-(2-phenylethenyl) 1,3-benzodiazepine derivatives useful for the treatment of cancer  
The present invention provides compounds of formula (1) acting as protein kinase (PK) and receptor kinase (RK) signaling modulators. The invention further provides methods of their preparation,...
9073855 BCL-2 selective apoptosis-inducing agents for the treatment of cancer and immune diseases  
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 or Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which are expressed...
9073851 Compositions and methods for treating cancer  
Provided herein are methods and compositions inter alia for treating diseases, including hyperproliferative diseases, migraine headaches, and depression.
9072776 Anti-cancer combination treatment and kit-of-parts  
In one aspect the present invention relates to pharmaceutical kits of parts suitable for treating neoplastic diseases such as cancer comprising an anti-cancer medicament, a Basidiomycete bioactive...
9072748 BCL-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases  
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 or Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which are expressed...
9072735 Proteinases destroy cancer tumor's solid structure and kill cancer cells locally  
A proteinase therapy has been invented to eliminate solid tumors by destroying tumors' solid structure and killing cancer cells by cleaving vital extracellular matrix proteins C-terminally,...
9072729 Method for treating fibrosis and cancer with imidazolium and imidazolinium compounds  
There is presently provided methods for delivering an anti-fibrotic or anti-cancer agent to a cell. The methods comprise contacting a cell with an effective amount of imidazolium and imidazolinium...
9072698 Method for screening anti-cancer compounds inhibiting function of TM4SF5 and anti-cancer composition containing chalcone compounds  
The present invention relates to a method for screening an anticancer compound and an anticancer compound screened using the method, and more particularly, to a method for screening an anticancer...
9068231 Method for screening cancer therapeutic agent using galectin-3, GSK-3β, and fascin-1  
Disclosed is a method for screening a novel cancer therapeutic agent. The cancer therapeutic agent exhibits down-regulation of galectin-3 and fascin-1 or interferes with the interaction between...