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9060993 Compositions and methods for treating cancer  
Methods of treating individuals identified as having cancer using ATP citrate lyase inhibitor and/or tricarboxylate transporter inhibitor are disclosed. Methods of inducing apoptosis in cancer...
9060974 Prostate cancer therapy using an engineered respiratory syncytial virus  
The present invention is within the field of oncolytic virotherapy. Oncolytic virotherapy is a strategy using viruses, naturally occurring or genetically modified, to selectively target and...
9060961 Molecules and methods for treatment and detection of cancer  
The invention provides a method for inhibiting proliferation of cancer cells, as well as methods for detecting and treating various cancers, including cancer of the ovary, breast, prostate and...
9058910 Charged particle beam acceleration method and apparatus as part of a charged particle cancer therapy system  
The invention comprises a charged particle beam acceleration method and apparatus used as part of multi-axis charged particle radiation therapy of cancerous tumors. The accelerator includes a...
9057729 Vitro method of detecting and/or diagnosing cancer using UV light based DNA image cytometry  
The invention relates to a method of determining in vitro the amount of nuclear DNA within a human or animal cell using UV absorption measurement with UV light. The invention also relates to a...
9057107 Molecular biomarker set for early detection of ovarian cancer  
Embodiments of the present invention concern methods and compositions related to detection of ovarian cancer, including detection of the stage of ovarian cancer, in some cases. In particular, the...
9057068 Methods and compositions using miR-3151 in the diagnosis and treatment of cancer  
Compositions comprising therapeutic oligonucleotide compounds that target the expression of genes associated with tumorigenesis or cell transformation are provided. Methods are described to...
9057055 Method of obtaining circulating cancer cell populations  
It is herewith provided methods of obtaining circulating cancer cells (CCCs)-enriched cellular populations based on the removal of CD45-positive cells from an apheresis product. It is also...
9056857 Methods for treating or preventing cancer and neurodegenerative diseases  
Provided are methods of treating or preventing a neurodegenerative disease comprising administering to a subject having a neurodegenerative disease an effective amount of a compound of Formula I:...
9056135 MicroRNA biomarkers for human breast and lung cancer  
The present invention relates to novel molecular markers for diagnosis and classification of human breast cancer and lung cancer.
9056133 Pharmaceutical kit and method for treating cancer  
This invention is related to the field of cancer treatment, more specifically to gene therapy in combination with a suitable chemotherapeutic agent. The present invention is related to a new...
9056128 Adjuvant used in dielectric heating-assisted cancer treatment, and cancer treatment method  
There is provided an adjuvant capable of enlarging an ablation area and reducing ablation unevenness in a dielectric heating-assisted cancer treatment such as radiofrequency ablation used for...
9056098 Hemoglobin-based oxygen carrier-containing pharmaceutical composition for cancer targeting treatment and prevention of cancer recurrence  
The present invention provides a pharmaceutical composition containing a hemoglobin-based oxygen carrier for treating cancer, preventing recurrence and metastasis of cancerous tumor. The...
9056070 Autologous biological cancer vaccine  
The present disclosure relates to an autologous biological cancer vaccine and to a method for preparing the same. The vaccine of the present application is a biological vaccine obtained from...
9056069 Cancer therapy based on tumor associated antigens derived from cyclin D1  
The present invention relates to cyclin D1-derived peptides for use in the improved treatment of cancer in a patient, particularly in the form of a combination therapy using a vaccine. Other...
9052318 Absorbent paper and use thereof for breast cancer detection  
Biological samples of mammary fluid or components thereof are obtained using a breast pump device coupled with an absorbent paper or membrane, optionally facilitated by administering oxytocin to...
9051619 Methods and compositions for prostate cancer metastasis  
Provided are methods and compositions for determining an increased likelihood of prostate cancer cells in a subject to metastasize.
9051618 Methods for diagnosing lung cancer using MicroRNA signatures  
The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis.
9051617 Markers for breast cancer  
Correlations between polymorphisms and breast cancer are provided. Methods of diagnosing, prognosing, and treating breast cancer are provided. Systems and kits for diagnosis, prognosis and...
9051562 Polypeptides isolated from brevibacterium aurantiacum and their use for the treatment of cancer  
The present invention relates to methods and pharmaceutical compositions for treating cancer. More specifically, the invention relates to a polypeptide isolated from Brevibacterium aurantiacum...
9051385 Compositions employing alternative reading frame polypeptides for the treatment of cancer and infectious disease  
Provided are alternative reading frame (ARF) polypeptides as well as antigen presenting cell (APC) and dendritic cell (DC) based compositions that comprise ARF polypeptides. ARF polypeptides and...
9051377 Method for treating breast cancer using antibody binding to MMP-14  
Proteins that bind to matrix metalloproteinase 14 and methods of using such proteins are described.
9051372 Anti-CD70 antibody and its use for the treatment of cancer and immune disorders  
Disclosed are CD70 binding agents, such as anti-CD70 antibodies and derivatives, that induce a cytotoxic, cytostatic or immunosuppressive without conjugation to a therapeutic agents, as well as...
9051348 Ginsenoside with anti-cancer activity and the preparation method thereof  
The present invention relates to a novel compound derived from ginsenoside Rh2, the preparation methods and the use thereof in treating cancers.
9051271 Substituted pyridine derivatives useful in the treatment of cancer  
The present invention describes compounds of formula (I) Wherein: R1 is selected from C1-C6 alkyl, CF3, Phenyl & 2-thienylR2 is selected from C1-C6 alkyl, phenyl & CF3 R3 is selected from H, C1-C6...
9050340 Compositions of engineered human arginases and methods for treating cancer  
Compositions and methods for the treatment of cancer are described, and, more preferably, to the treatment of cancers that do not express, or are otherwise deficient in, argininosuccinate...
9046589 Dynamic MR imaging of patients with breast cancer—establishment and comparison of different analytical methods for tissue perfusion and capillary permeability  
The present invention encompasses methods, apparatus, and computer based systems for identifying benign and malignant tumors in tissues such as soft tissues and particularly breast tissue using...
9046522 Markers for endometrial cancer  
The invention relates to the surprising finding that biomarkers corresponding to ACAA1, AP1M2, CGN, DDR1, EPS8L2, FASTKD1, GMIP, IKBKE, P2RX4, P4HB, PHKG2, PPFIBP2, PPP1 R16A, RASSF7, RNF183,...
9046521 Cancer evaluation method using haptoglobin β chain defined by antibody RM2  
The object of the present invention is to identify a molecule that is specifically recognized by antibody RM2 in tissue or serum of a cancer patient, and provide a method for diagnosing cancer in...
9045802 Method and probe set for detecting cancer  
Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected...
9045756 Compositions and methods for treating cancer and other diseases  
Aptamers and improved aptamers are provided with enhanced efficacy for binding to target molecules in vivo or for treating cancer or other diseases. Such improvements in aptamers are provided that...
9045556 Therapeutic agent for cancer  
The present invention provides an adjuvant for cancer antigen peptide vaccines and virus antigen peptides, containing a pertussis vaccine as a primary ingredient. The present invention also...
9045545 Precision medicine by targeting PD-L1 variants for treatment of cancer  
The invention relates to human targets of interest (TOI), anti-TOI ligands, kits compositions and method.
9045475 Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases  
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic...
9045450 Method for chemical synthesis of antrocin and use thereof for suppressing non-small cell lung cancer  
The present invention provides a method for preparing antrocin of pharmaceutically acceptable salts thereof via a series of gold-catalyzed cyclization to construct the (6-6-5) tricyclic core...
9045420 Bcl-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases  
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 or Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which are expressed...
9044506 MIR-21 promoter driven targeted cancer therapy  
The invention provides a nucleic acid construct comprising a promoter sequence derived from microRNA-21 (miR-21) linked to a nucleic acid sequence encoding an anti-cancer agent, an example of...
9044474 Compositions and methods for increasing drug efficacy in cancer  
A method of (a) treating a lymphoproliferative disease in a subject in need thereof; (b) slowing the progression of lymphoproliferative disease in a subject who has been diagnosed with a...
9044467 Methods for assisting anti-cancer drugs  
A method for assisting an anti-cancer drug comprising administrating an effective amount of Antrodia camphorata fermentation solution to improve life quality of patient suffering from cancers...
9044464 No-releasing guanidine-coxib anti-cancer agents  
The present disclosure provides NO-releasing guanidine-coxib anti-cancer agents, having the structure of Formula (I): wherein R1, R11, Z and L are as defined in the detailed description;...
9044461 Transcobalamin receptor polypeptides, nucleic acids, and modulators thereof, and related methods of use in modulating cell growth and treating cancer and cobalamin deficiency  
The present invention provides the amino acid and polynucleotide sequences of the transcobalamin receptor, as well as modulators of the transcobalamin receptor. Accordingly, the present invention...
9044432 Compositions and methods for cancer detection and treatment  
Disclosed herein are compositions and methods for cancer detection and treatment. Compounds that inhibit PRMT5 are contemplated, as are pharmaceutical compositions comprising a therapeutically...
9040671 Methods for cancer management targeting Co-029  
The present disclosure relates to a Co-029 inhibitor for inhibiting the migration of cancer cells which express Co-029. The disclosure relates to a Co-029 inhibitor for the treatment of cancer...
9040574 Method of treating androgen independent prostate cancer  
The present invention is directed to a method treating prostate cancer. The method comprises administering to a patient in need thereof at least one compound selected from...
9040505 Benzoquinone derivative E3330 in combination with chemotherapeutic agents for the treatment of cancer and angiogenesis  
Disclosed are novel methods for the therapeutic treatment of cancer and angiogenesis. The enzyme Ape1/Ref-1, via its redox function, enhances the DNA binding activity of transcription factors that...
9040501 Compositions and methods for treating cancer  
Provided herein are compounds used to inhibit the deamination enzyme responsible for the inactivation of therapeutic compounds, and methods of using them.
9040497 Treatment and diagnosis of colon cancer  
The present invention discloses novel agents and methods for diagnosis and treatment of colon cancer. Also disclosed are related arrays, kits, and screening methods.
9040286 Diagnosis and treatment of cancer  
Provided herein are methods for diagnosing cancer by determining the level of expression of SETDB1 in a biological sample. Also provided herein are methods for treating cancer by administering an...
9040100 Methods for inhibiting prostate cancer by kinases and angiogenesis inhibitory mechanisms of ball moss extract  
A method of treating prostate cancer by administering a pharmaceutically-acceptable amount of a crude extract of the indigenous Jamaican plant Ball Moss (Tillandsia Recurvata) comprising one or...
9040081 Use of lipid containing particles comprising Quillaja saponins for the treatment of cancer  
The present invention relates to the use of lipid containing particles, such as liposomes, iscom and/or iscom matrix and posintros, comprising at least one lipid and at least one saponin for the...