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8058243 |
Method for treating a brain cancer with ifenprodil
A clonogenic neurosphere assay is described that carries out high throughput screens (HTS) to identify potent and/or selective modulators of proliferation, differentiation and/or renewal of neural...
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8058020 |
Method of detecting cancer using delta-catenin
The present invention provides a method for detecting or screening for the presence of cancer in a subject. The method comprises obtaining, providing or collecting a tissue or fluid sample (such as...
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8058003 |
ADRB2 cancer markers
The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to...
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8057996 |
Nucleic acids and corresponding proteins entitled 202P5A5 useful in treatment and detection of cancer
A novel gene 202P5A5 and its encoded protein, and variants thereof, are described wherein 202P5A5 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the...
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8053583 |
Anti-cancer compound and manufacturing method thereof
Anti-cancer compounds and manufacturing methods thereof are disclosed. The anti-cancer compounds are 1,8-diamidoanthraquinone derivatives with amino compounds. The manufacturing method includes the...
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8053552 |
Neopeptides and methods useful for detection and treatment of cancer
The present invention relates to compounds and methods useful for the detection and treatment of disorders associated with frameshift mutations in coding microsatellite regions. The compounds and...
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8053477 |
Inhibitors of the S100-p53 protein-protein interaction and method of inhibiting cancer employing the same
Compounds that bind S100 and inhibit the S100-p53 protein-protein interaction and activate the tumor suppressor activity of p53, and thus which have an antineoplastic effect are disclosed, as well...
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8053422 |
Anti-cancer oligodeoxynucleotides
It is disclosed herein that suppressive ODNs are of use for preventing or delaying the formation of a tumor, reducing the risk of developing a tumor, treating a tumor, preventing conversion of a...
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8053406 |
Compositions for the treatment of cancer, and methods for testing and using the same
A composition comprising leukotoxin proteins isolated from a bacterium is provided. In this composition, greater than 85% of the leukotoxin proteins are chemically modified at a basic amino acid...
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8053207 |
Cancer diagnosis by measuring polyisoprenylated methylated protein methyl esterase activity
Methods for cancer diagnosis and treatment; in particular, methods for diagnosis and treatment of triple negative breast cancer by measuring the activity of PMPMEase.
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8053196 |
Clinical assays for thrombospondin fragments in the detection, diagnosis, and evaluation of cancer
The invention relates to thrombospondin fragments found in plasma, their use or use of portions thereof in diagnostic methods, as method calibrators, method indicators, and as immunogens, and as...
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8053193 |
Method and apparatus for judging the presence or absence of cancer cell
The invention provides a method for judging whether cancer cells are present or not in a sample, comprising a obtaining step of obtaining values related to an expression level of a caner marker...
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8053189 |
Method for the diagnosis of colorectal cancer
The object of the present invention refers to an in vitro method for diagnosing colorectal cancer based on the determination from a biological sample obtained from a subject, of promoter...
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8053183 |
Method of diagnosing esophageal cancer
In order to identify the molecules involved in esophageal carcinogenesis and those to be useful for diagnostic markers as well as targets for new drugs and immunotherapy, a cDNA microarray...
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8052966 |
Methods and compositions for treating metastatic cancer
Methods and compositions for producing targeted delivery vectors are provided. Such vectors are useful for treating neoplastic disorders. Also provided are protocols for administering targeted...
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8048676 |
Systems of diagnosing cervical cancer
The invention provides reagents and methods for detecting pathogen infections in human samples. This detection utilizes specific proteins to detect the presence of pathogen proteins or abnormal...
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8048634 |
Cancer screening method
A method for screening cancer comprises the following steps: (1) providing a test specimen; (2) detecting the methylation rate of the CpG sequence in at least one target gene of the test specimen,...
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8048621 |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
The present invention provides diagnostic and prognostic methods for predicting the effectiveness of treatment of a cancer patient with an IGF-1R kinase inhibitor. Methods are provided for...
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8048455 |
Treatment of cancer and inflammatory disorder
Disclosed are extracts, compositions, and methods for treating cancer and inflammatory disorders. Also disclosed are methods for preparing extracts or compounds for treating the disorders.
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8045679 |
Charged particle cancer therapy X-ray method and apparatus
The invention comprises an X-ray method and apparatus used in conjunction with charged particle or proton beam radiation therapy of cancerous tumors. The system uses an X-ray beam that lies in...
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8044095 |
Mixture of catechins or rather polyphenols extracted from chinese green tea or other vegetables for the prevention of prostate cancer and for the treatment of prostate hypertrophy (BPH)
The formulation and modality of use of a pharmaceutical preparation having the properties described below is described. This preparation is a product comprising a mixture of catechins or...
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8044033 |
Fluorocytidine derivatives and COX-2 inhibitors for the treatment of cancer
The present invention provides, in certain embodiments, methods for the treatment of colorectal cancer comprising administering a COX-2 inhibitor and fluorocytidine derivative to a human patient....
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8043835 |
Methods for detecting and monitoring cancer using extracellular RNA
The invention provides methods, reagents and kits for using extracellular RNA in bodily fluids including plasma and serum to detect, infer, or monitor diseases such as cancer and other neoplasia.
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8043815 |
Methods for analysis of PDEF and survivin as interconnected cancer biomarkers and targets for personalized medicine
Provided are methods for determining whether an individual is a candidate to receive treatment with a DNA methylation inhibitor. The method can be performed a biological sample of cancerous tissue...
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8043807 |
Methods and kits for determining a risk to develop cancer, for evaluating an effectiveness and dosage of cancer therapy and for correlating between an activity of a DNA repair enzyme and a cancer
Methods and kits for (i) determining a risk of a subject to develop cancer; (ii) evaluating an effectiveness and dosage of cancer therapy administered to a cancer patient; and (iii) determining a...
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8043623 |
Immunogenic peptides for the treatment of prostate and breast cancer
Immunogenic T-cell receptor gamma Alternate Reading Frame Protein (TARP) polypeptides are disclosed herein. These immunogenic TARP polypeptides include nine consecutive amino acids of the amino...
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8039603 |
Nucleic acid and corresponding protein entitled 121P1F1 useful in treatment and detection of cancer
A novel gene (designated 121P1F1) and its encoded protein, and variants thereof, are described wherein 121P1F1 exhibits tissue specific expression in normal adult tissue, and is aberrantly...
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8039511 |
Use of isothiocyanates compounds in treating prostatic diseases and skin cancer
A method for preventing and treating prostatic diseases and skin cancer using naturally or artificially synthesized isothiocyanates compounds or the derivatives or metabolites thereof.
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8039218 |
Detection of cancer cells in body fluids
A method of detecting circulating melanoma or carcinoma cells in a subject. The method comprises obtaining a body fluid from a subject and detecting the expression of a panel of genes in the body...
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8039000 |
Nucleic acid and corresponding protein entitled 158P3D2 useful in treatment and detection of cancer
A novel gene (designated 158P3D2) and its encoded protein, and variants thereof, are described wherein 158P3D2 exhibits tissue specific expression in normal adult tissue, and is aberrantly...
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8038999 |
Breast cancer eradication program
A method of treating breast cancer that is at least partially ER+ is disclosed. The method comprises administering at a tumor site in a mammalian subject a pharmaceutically acceptable form of...
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8038998 |
Methods of cancer therapy targeted against a cancer stemline
Improved methods for treatment of cancer which involve the targeting of slow-growing, relatively mutationally-spared cancer stem line are provided. These methods are an improvement over previous...
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8038996 |
Composition and method for cancer treatment
Anti-CEACAM6 antibodies and antibody fragments, nucleic acids encoding them, methods of their manufacture, and methods to treat cancer using these compounds are provided.
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8036435 |
Cancer detection, diagnosis, staging, treatment planning, delivery, and monitoring using X-ray attenuation coefficient distributions
A method of analyzing a volumetric data set obtained by an imaging system from an object is provided includes defining a first region of interest comprising a population of voxels of a first tissue...
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8034959 |
Methods of treating cancer with an antibody-drug conjugate
The present invention provides analogues of duocarmycins that are potent cytotoxins. Also provided are peptidyl and disulfide linkers that are cleaved in vivo. The linkers are of use in forming...
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8034914 |
Nucleic acid constructs, pharmaceutical compositions and methods of using same for treating cancer
A nucleic acid construct that includes (i) a first nucleic acid sequence encoding TNF alpha; (ii) a second nucleic acid sequence encoding a Diphtheria toxin; and (iii) at least one additional...
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8034824 |
Iontophoretic preparation for treatment of breast cancer and/or mastitis
The present invention is to provide means to treat breast cancer and/or mastitis by topically administering a non-steroidal antiinflammatory analgetic agent and/or an anticancer agent and allowing...
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8034815 |
Compounds and method for treatment of cancer
The present invention is directed to a compound of Formula I: and/or a pharmaceutically-acceptable salt, hydrate, solvate, tautomer, optical isomer, or combination thereof, a composition comprising...
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8034797 |
Triazene compounds for the treatment of cancer
The present invention relates to novel triazene compounds, to a process for their preparation, to pharmaceutical compositions comprising them, and to the use thereof in the treatment of cancer...
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8034792 |
Insulin-like growth factor binding protein 7 for treatment of cancer
Methods of treating a tumor in a subject include identifying a subject having, at risk for, or suspected of having a tumor, and administering to the subject an effective amount of an IGFBP7 agent...
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8034782 |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a...
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8034781 |
Angiotensin-(1-7) and angiotensin-(1-7) agonists for inhibition of cancer cell growth
The present invention describes the use of angiotensin-(1-7) peptide as an anti-cancer therapeutic. Thus, in one embodiment, the present invention comprises a composition to inhibit the growth of...
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8034578 |
PKP3 oncogene as a prognostic indicator for lung cancer
The present invention provides the method of predicting an non-small cell lung cancer (NSCLC) prognosis.
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8034577 |
Methods and probes for detecting esophageal cancer
Probe sets and methods of using probes and probe sets for selectively detecting high grade dysplasia and esophageal adenocarcinoma or low grade dysplasia from biologic samples are described....
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8034565 |
Gene expression markers for breast cancer prognosis
The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer.
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8034549 |
Detection of cancer by elevated levels of BCL-2
The present invention relates to a method for the diagnosis, prognosis, and monitoring of cancer, such as early or late stage ovarian cancer, in a subject by detecting Bcl-2 in a biological sample...
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8034548 |
Methods and materials for assessing prostate cancer therapies
Using microarray-based profiling of isogenic prostate cancer xenograft models, we found that a modest (2-5 fold) increase in androgen receptor (AR) mRNA was the only expression change consistently...
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8034388 |
Anthocyanin-rich compositions and methods for inhibiting cancer cell growth
The present invention provides compositions and methods for inhibiting the growth and cell cycle progression in carcinoma cells comprising the step of contacting the cells with an anthocyanin rich...
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8034386 |
Extract from Agaricus blazei Murill capable of suppressing breast cancer
A food material capable of suppressing the genesis of breast cancer or proliferation of terminal breast cancer. An extract of Agaricus Blazei Murill comprising an ingredient capable of suppressing...
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8034360 |
Use of human prostate cell lines in cancer treatment
The invention here relates to a product comprised of a cell line or lines intended for use as an allogeneic immunotherapy agent for the treatment of cancer in mammals and humans. All of the studies...
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