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9980951 Image guided therapy for cancer  
The invention provides a method to treat cancer in an animal comprising administering a tetra-arylethylene cation to the animal.
9977033 Methods for assessing cancer recurrence  
Certain embodiments are directed to methods of identifying a subject having a higher risk of prostate cancer recurrence. The methods can include the step of measuring levels of one or more of...
9976188 Cancer biomarkers  
Biomarkers and methods using the biomarkers for the prediction of the recurrence risk of cancer in a patient are provided.
9976187 Methylation biomarkers for prostate cancer  
Different combinations of methylation status based biomarkers can be used to test for prostate cancer with high sensitivity and high specificity.
9974844 Cancer vaccine compositions and methods of using the same  
The present invention provides methods and compositions for the stimulation of immune responses. In particular, the present invention provides nanoemulsion compositions and methods of using the...
9974830 Molecular signature of cancer  
The present invention provides compounds, compositions, and methods for detecting, diagnosing and treating cancers such as glioblastoma multiforme.
9974766 Prenylated isoflavones for treatment of subjects with multidrug-resistant cancer  
Prenylated isoflavones are suitable to specifically inhibit P-glycoprotein in multidrug-resistant cancer cells leading to an accumulation of cytotoxic compounds or therapeutic compounds in the...
9974760 Compositions and methods for treating cancer  
The present invention provides, in part, compositions and methods for treating cancer using a combination of C6-ceramide and other anti-cancer agents.
9970937 Composition and method for diagnosis and immunotherapy of prostate cancer  
A method and composition for the diagnosis of and treatment of prostate cancer including a recombinant AKAP-4 tumor-associated antigen loaded antigen presenting cell that generates an AKAP-4...
9970012 Replication factor C-40 (RFC40/RFC2) as a prognostic marker and target in estrogen positive and negative and triple negative breast cancer  
The present disclosure relates generally to cancer and particularly to breast cancer including estrogen sensitive, estrogen resistant and triple negative breast cancer (TNBC), and to methods of...
9969781 Compositions and methods to treat cancer with CpG rich DNA and cupredoxins  
The present invention relates to compositions comprising CpG rich DNA from Pseudomonas aeruginosa. The compositions optionally comprise a cupredoxin. The present invention includes specific CpG...
9969715 Compounds useful for treating cancer  
The present invention relates to a compound of formula (I): wherein A and A′ independently represent a phenylene group or a pyridylene group; R2 is a hydrogen atom or a (C1-C4)alkyl group; R3 is a...
9969699 Cancer cell growth inhibitor, anticancer agent, and method for screening same, as well as novel compound  
A cancer cell proliferation inhibitor including at least one selected from compounds represented by Structural Formulae (1) to (8), wherein the cancer cell is at least one of a cancer cell...
9968685 Methods to treat cancer with cupredoxins  
The present invention discloses methods and materials for killing and/or inhibiting the growth of a cancer cell via preferential entry of a cytotoxic compound. Preferential entry of the cytotoxic...
9968619 Method of treating triple-negative breast cancer using thienotriazolodiazepine compounds  
A method of treating triple-negative breast cancer in a mammal comprising the step of: administering to a patient a pharmaceutical acceptable amount of a compound being a thienotriazolodiazepine...
9968606 Deuterated compounds for treating cancer and related diseases and conditions, and compositions and methods thereof  
The invention provides novel chemical compounds useful for treating cancer or a related disease or disorder thereof, and pharmaceutical composition and methods of preparation and use thereof.
9968570 Compositions and methods for treating cancer  
The present invention provides, in part, compositions and methods for treating cancer using a combination of C6-ceramide and other anti-cancer agents in certain vesicles.
9965585 Detection of genetic or molecular aberrations associated with cancer  
Systems, apparatus, and methods are provided for determining genetic or molecular aberrations in a biological sample. Biological samples including cell-free DNA fragments are analyzed to identify...
9964542 Bladder cancer detection composition, kit, and associated methods  
Compositions, kits, and methods for the diagnosis, prognosis, and monitoring of bladder cancer in a subject are provided by detecting in a urine sample a combination of biomarkers. In one...
9963747 Methods for the identification, assessment, and treatment of patients with cancer therapy  
The present invention is directed to the identification of predictive markers that can be used to determine whether patients with cancer are clinically responsive or non-responsive to a...
9963746 Composition or kit for making a prognosis of liver cancer, and method for making a prognosis of liver cancer  
The present disclosure provides a marker for predicting prognosis of liver cancer, a composition or kit for predicting prognosis of liver cancer, preferably, a composition or kit for predicting...
9963703 Compositions and methods for treating pancreatic cancer  
Provided herein are composition for sensitizing tumors to anti-tumor therapies. The compositions include antisense oligonucleotides against TGFβ2, wherein the compositions sensitize tumors to...
9963701 Pharmaceutical composition for treatment of radiation- or drug-resistant cancer comprising HRP-3 inhibitor  
The present invention relates to a pharmaceutical composition for treating a radiation- or drug-resistant cancer, containing an agent capable of inhibiting the expression of hepatoma-derived...
9963695 Diagnosis of prostate cancer  
The invention provides methods for isolating RNA from whole urine and urine fractions for the diagnosis of prostate cancer and/or benign prostate hyperplasia. An exemplary method for diagnosing...
9963486 Peptidomimetics for treating HER2-overexpressed cancer  
Novel peptidomimetic compounds are disclosed, compounds that inhibit protein-protein interactions (PPI) of epidermal growth factor receptors (EGFR), also called human epidermal growth factor...
9963485 Cycloheptapeptide agents for treatment of cancer and obesity diseases  
New anticancer and anti-obesity agents based on cyclic peptide compounds are isolated from the stem barks of Maytenus variabilis (Loes.) C. Y. Cheng (Celastraceae). The invention also includes its...
9962403 Formulation drug of sodium ion and calcium ion for treating cancer, tumor and nonmalignancy  
The invention relates to a formulation cancer drug termed the “medicinal ion bomb” and its treatment methods. A mouse carcinoma, at 13mm x 13mm in size was killed by a single intratumoral...
9962373 Methods of treating bladder cancer  
The present invention provides methods and compositions for treating bladder cancer, including metastatic bladder cancer and non-muscle-invasive bladder cancer, by administering a composition...
9962341 Active pharmaceutical ingredient (API) comprising cannabinoids for use in the treatment of cancer  
The present invention relates to an active pharmaceutical ingredient (API) which comprises or consists essentially of cannabidiol (CBD) and one other cannabinoid selected from cannabigerol (CBG),...
9962225 Method and apparatus for skin cancer thermal therapy  
An apparatus for treatment of soft tissue includes a source of radiation, a handpiece which is adapted to transmit radiation emitted from the source of radiation to a region of soft tissue,...
9958663 Light-trapping cancer cell stage testing method  
A light-trapping cancer cell stage testing method includes: measuring a first average escape velocity or range of first cancer cells and a second average escape velocity or range of second cancer...
9958447 Immunoassay of S-adenosylmethionine in personalized medicine and health or cancer evaluation  
The invention provides a method of detecting the presence or absence of a disease in a patient wherein said disease is accompanied by deficient levels of S-adenosylmethionine comprising:...
9957575 Methods for detecting CpG methylation and for diagnosing cancer  
The present invention relates to the field of pharmacogenomics and in particular to detecting the presence or absence of hypermethylated DNA. The detection of CpG methylation in marker DNA is...
9957573 EML4-ALK translocations in lung cancer  
The present disclosure relates to methods for the diagnosis and evaluation of neoplastic disorders, particularly non-small cell lung cancer. Assays are described in which patient test samples are...
9957570 DNA hypermethylation diagnostic biomarkers for colorectal cancer  
The present invention relates to the field of cancer. More specifically, the present invention relates to the use of biomarkers to detect colorectal cancer. In one aspect, the present invention...
9957569 Recurrent gene fusions in prostate cancer  
Recurrent gene fusions in prostate cancer of androgen regulated genes or housekeeping genes and ETS family member genes are described. Compositions and methods having utility in prostate cancer...
9957302 Treating cancer with viral nucleic acid  
This document provides methods and materials related to the use of nucleic acid coding for viruses to reduce the number of viable cancer cells within a mammal. For example, methods for using...
9957301 Therapy of cancer based on targeting adaptive, innate and/or regulatory component of the immune response  
The invention relates to a kit of parts, suitable for use in a therapy of cancer, wherein said kit comprises: (i) a recombinant protein comprising one or several polypeptides bearing one or...
9957236 Selective inhibitors interfering with fibroblast growth factor receptor and FRS2 interaction for the prevention and treatment of cancer and other diseases  
The present technology relates to medicine and includes the use of inhibitors which selectively interfere with the interaction between a fibroblast growth factor receptor and FRS2, and with the...
9956305 Organ protection in PSMA-targeted radionuclide therapy of prostate cancer  
A method of reducing radiation exposure of a non-cancerous tissue of a patient diagnosed with a cancer includes administering to the patient an agent capable of competing for binding sites on a...
9956303 Anti-met therapy for previously diagnosed cancer patients  
The present invention relates to methods useful in the selection of cancer patients suitable for treatment with therapies directed at c-Met. The method employs imaging agents which comprise...
9956215 Methods of treating cancer with farnesyltransferase inhibitors  
The present invention relates to the field of cancer therapy. Specifically, provided are methods of treating cancer, for example, peripheral T-cell lymphoma (“PTCL”), with a farnesyltransferase...
9956208 Compounds for the treatment of cancer and inflammatory diseases  
The present invention relates to novel compounds and pharmaceutical compositions thereof which may be useful in the treatment and/or prevention of various conditions. The present invention also...
9955898 Cancer diagnosis method using respiratory gas  
A method for diagnosing cancer, comprises detecting volatile organic compounds (VOCs) contained specifically in exhaled breath of cancer patients, and more particularly, to a method for providing...
9953129 Patient stratification and determining clinical outcome for cancer patients  
In a first aspect the present invention is directed to a method of generating a scheme allowing classification of a cancer of an individual patient for estimating a clinical outcome for said...
9952221 Methods for screening, predicting and monitoring prostate cancer  
Biomarkers are identified by analyzing gene expression data using support vector machines (SVM) to rank genes according to their ability to separate prostate cancer from normal tissue. Expression...
9951390 Prostate cancer prognostic compositions and kits  
Described herein are method, compositions and kits for prognosis of prostate cancer. The methods include determining the ratio of PCA3 and of a prostate-specific marker expression in a urine...
9951388 Spectral imaging for measurement of nuclear pathology features in cancer cells prepared for in situ analysis  
In general, the presently disclosed technology relates to identification of cancer subtypes. More specifically, the technology relates to methods for determining molecular drivers of cancer and/or...
9951114 Recombinant cancer therapeutic cytokine  
Recombinant therapeutic cytokines (“therakines”) for the treatment of cancer are provided. The recombinant therakines include a truncated region of MDA-7/TL-24 (“M4”) not normally found in nature...
9951111 Type I interferon mimetics as therapeutics for cancer, viral infections, and multiple sclerosis  
The subject invention pertains to agonist peptides of type I interferons and methods of using the peptides. These peptides are based on the amino acid sequence of the C-terminus region of the type...