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9700588 Use of parvovirus for eliminating cancer stem cells (CSCs)  
Described is the use of a parvovirus, preferably H-1PV, for the therapeutical elimination of cancer stem cells (CSCs), preferably neuroblastoma stem cells and glioblastoma stem cells.
9700580 Method for cancer treatment  
A method of treating humans with cancer by intravenously administering a single dose of arsenic trioxide in a phosphate buffered saline solution having a pH less than 8.0 in a dosage amount of...
9700572 Anti-cancer agent  
The present invention is intended to provide a novel anticancer agent which is effective to a cancer. After administering an agent prepared using burdock fruit extract to a pancreas cancer patient...
9696320 Lung cancer differential marker  
An object of the present invention is to develop and provide a lung cancer differential marker with which lung cancer can be diagnosed conveniently and highly sensitively without depending only on...
9696312 Diagnosis and treatment of cancer expressing ILT3 or ILT3 ligand  
The present invention relates to methods of using the expression of ILTL3 ligand or ILT3 on certain types of cancer cells as a diagnostic tool. Methods are provided for treating ILT3-ligand...
9696311 Detection of cancer through breath comprising a sensor array comprising capped conductive nanoparticles  
Sensor array for detecting biomarkers for cancer in breath samples. The sensor array is based on 2D films or 3D assemblies of conductive nanoparticles capped with an organic coating wherein the...
9695200 Heterocyclic ITK inhibitors for treating inflammation and cancer  
Disclosed herein are heterocyclic compounds and compositions useful in the treatment of ITK mediated diseases, such as inflammation, having the structure of Formula (I): wherein R1, R2, and X are...
9695174 Inhibitor of breast cancer resistance protein (BCRP)  
Disclosed are compounds that inhibit breast cancer resistance protein (BCRP), of which compound (I-1),...
9694128 Device and method for administering an anti-cancer substance  
An anti-cancer substance is administered via the patient's blood ex vivo and in line by establishing a connection between the patient and a device having a chamber containing the anti-cancer...
9694088 Pro-drug form (P2PDox) of the highly potent 2-pyrrolinodoxorubicin conjugated to antibodies for targeted therapy of cancer  
Disclosed are methods, compositions and uses of conjugates of prodrug forms of 2-pyrrolinodoxorubicin (P2PDox) with antibodies or antigen-binding fragments thereof (ADCs), with targetable...
9694083 Methods and systems for treating or preventing cancer  
The present invention generally relates to compositions and methods for treatment of subjects having or at risk of cancer or other conditions. In some cases, the composition may include nitric...
9694072 Methods for diagnosing and treating neuroendocrine cancer  
The present invention relates to a method for diagnosing neuroendocrine cancers via detecting the presence of N-methyl D-asparate-associated (NMDA) glutamate receptors type 1 and/or type 2....
9694059 Ex vivo, fast and efficient process to obtain activated antigen-presenting cells that are useful for therapies against cancer and immune system-related diseases  
The present invention relates to an ex vivo, fast and efficient process to obtain activated antigen-presenting cells that are useful for therapies against cancer and immune system-related...
9694033 IL-9 secreting CD8+ Tc9 cells and methods of treating cancer  
A method of producing a population of CD8+ Tc9 lymphocytes is provided including priming a population of naïve CD8+ T cells by contacting the population of naïve CD8+ T cells with an immunogenic...
9694015 Methods for the treatment of locally advanced breast cancer  
Provided herein are methods of treating, preventing and/or managing locally advanced breast cancer, including inflammatory breast cancer, which comprise administering to a patient one or more...
9694005 Nonsteroidal and steroidal compounds with potent androgen receptor down-regulation and anti prostate cancer activity  
Nonsteroid and steroid compounds that cause down-regulation of the androgen receptor (AR), both full length and splice variant, induce apoptosis and inhibit proliferation of inhibiting...
9694001 Combination therapy using azabicyclo compound for cancer  
Provided is a novel method for treating cancer using an HSP90 inhibitor which exhibits a markedly superior antitumor effect and has a reduced side effect. An antitumor agent is characterized in...
9694000 ITE for cancer intervention and eradication  
A method of cancer intervention or eradication by administering an effective amount of an endogenous ligand for the aryl hydrocarbon (Ah) receptor (AhR) named ITE or one of its analogs (the active...
9693957 Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders  
Metal-bisphosphonate nanoparticles are disclosed. Also disclosed are pharmaceutical compositions including the metal-bisphosphonate nanoparticles, methods of preparing the metal-bisphosphonate...
9693694 Cancer cell detection using dielectrophoretic dynamic light scattering (DDLS) spectroscopy  
Non-invasive apparatus and method for determining and monitoring glucose concentrations in human subjects. Glucose level is estimated through the effect of glucose on biological cells with glucose...
RE46453 Compositions comprising HPV polypeptides and immunoenhancement peptides for the treatment and prevention of cervical cancer  
The present invention relates to a fusion protein comprising a fusion polypeptide of E6 and E7 of a human papilloma virus, a signal peptide for secreting the polypeptide out of the cell, and an...
9689876 Methods related to cancer treatment  
The present invention relates to method for predicting a subject's relative response to cancer immunotherapy treatment. The methods involve providing a sample comprising a tumor cell or a...
9689874 Protein biomarker panels for detecting colorectal cancer and advanced adenoma  
Disclosed herein are panels related to the diagnosis or recognition of colon and colorectal cancer in a subject. The disclosed panels and related methods are used to predict or assess colon tumor...
9689862 Antigen binding protein and its use as addressing product for the treatment of cancer  
The present invention relates to an antigen binding protein, in particular a monoclonal antibody, capable of binding specifically to the protein Axl as well as the amino and nucleic acid sequences...
9689043 Method for treating muscle-invasive bladder cancer, containing S100A9 and EGFR inhibitors and cisplatin as active ingredients  
The present invention relates to a method for predicting the probability of muscle-invasive bladder cancer (MIBC) recurrence or metastasis, a method for providing information on a personalized...
9689041 Method and kit for determining in vitro the probability for an individual to suffer from colorectal cancer  
The present invention provides a method for determining in vitro, in a peripheral blood sample, the probability for an individual to suffer from a colorectal cancer, using the comparison of the...
9689039 Salivary biomarkers for lung cancer detection  
Presented herein are biomarkers related to lung cancer. The presently identified salivary biomarkers create the basis for a lung cancer detection bioassay with sensitivity and specificity. Means...
9688982 Methods and compositions for the treatment of cancer or other diseases  
The present invention relates to methods and compositions for the treatment of diseases, including cancer, infectious diseases and autoimmune diseases. The present invention also relates to...
9688764 Methods of treating breast cancer by administering anti-human prolactin receptor (PRLR) antibodies  
The present invention provides antibodies that bind to prolactin receptor (PRLR) and methods of using the same. According to certain embodiments, the antibodies of the invention bind human PRLR...
9688761 Biomarker profiles for predicting outcomes of cancer therapy with ERBB3 inhibitors and/or chemotherapies  
Provided are methods for optimizing therapy of, treating a patient having, or selecting (identifying) patients who will benefit from treatment for, a cancer (e.g., a non-hematological cancer;...
9688746 Immunoregulation in cancer, chronic inflammatory and autoimmune diseases  
The present invention primarily relates to a method for analyzing the amount of immunoregulatory integrin binding factors and/or patient endogenous antibodies which are directed against such...
9688674 Selective EP4 receptor antagonistic substance for treatment of cancer  
This invention provides a medicament for the treatment of cancer, which cause a reduction of cancer. This invention relates to use of a compound which has inhibitory activities against...
9688665 Methods of treating cancer  
The present invention relates to methods of treating cancer by administering the EZH2 inhibitor compounds and pharmaceutical compositions to subjects in need thereof. The present invention also...
9688640 Methods of treating cancer with a pyrazole derivative  
There is provided a compound of formula (I): or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a...
9687668 Treatment of cancer in body cavities and parts that are cavity-like  
The Body Cavity Cancer Treatment System achieves extremely uniform temperatures inside the tissue of the body cavity thereby realizing optimal efficacy in enhancing operation of the chemotherapy...
9687500 Methods and compositions for treating cancer  
Treatment of cancer by regional and prolonged release of one or more nucleotide-based agents is provided.
9687469 Agent containing flavonoid derivatives for treating cancer and inflammation  
A pharmaceutical composition for the prevention and treatment of cancer with specific flavanoid-based compounds selected from among the groups of Flavone, Flavanone and Flavanol, a method for the...
9687464 Anti-cancer agent delivery vehicles capable of improved loading  
There is provided a conjugate of a delivery agent containing a chemical moiety and at least one flavonoid. The flavonoid exists in a monomeric form or dimeric form before conjugation and remains...
9687458 Trans-clomiphene for use in cancer therapy  
The present invention relates to the administration of compositions comprising an antiestrogen, preferably a selective estrogen receptor modulator (SERM) such as trans-clomiphene, for treating...
9683995 Method of treatment of SETDB1 expressing cancer  
Provided herein are methods for diagnosing cancer by determining the level of expression of SETDB1 in a biological sample. Also provided herein are methods for treating cancer by administering an...
9683987 Gastric cancer cell line derived from murine gastric adenocarcinoma lacking p53 and E-cadherin and use thereof  
Provided is a gastric cancer cell line derived from a mouse deficient in E-cadherin and p53, and a use thereof. The E-cadherin- and p53-deficient, murine-derived gastric cancer cell line of the...
9683986 Treatment of cancer by inhibition of the MYD88/ERK MAP kinase interaction  
A method for selecting in vitro compounds is capable of potentiating the effect of a DNA damage inducing chemotherapy agent for the treatment of cancer, and includes selecting compounds inhibiting...
9683039 Notch agonists for the treatment of cancer  
The present invention is directed to methods of treating and preventing acute myeloid leukemia and acute myeloid leukemia relapse disease in a subject that involve administering a Notch receptor...
9683025 Methods and compositions for treating cancer and inflammatory diseases  
The invention provides a peptide construct comprising a cell penetrating peptide and an inhibitory peptide that interferes with the interaction between E1A and CtBP. The invention also provides...
9682996 Alpha helix mimetic compositions for treating cancer and other CBP/catenin-mediated diseases and conditions  
Alpha-helix mimetic structures and compounds represented by the formula (I) wherein the general formula and the definition of each symbol are as defined in the specification, a compound relating...
9682947 Substituted lactones for treating cancer  
Novel heterocyclo compounds represented by Formula I wherein X, R1, R2, R3, R4, R5, R6 and n are as described herein are provided. The compounds may be prepared as pharmaceutical compositions, and...
9682926 Cancer chemotherapeutic agent/formulation, manufacture and use thereof  
A cancer chemotherapeutic agent that is particularly kinase suppressing and/or any other signaling pathway interfering agents and pharmaceutical formulations/compositions involving the same and...
9682254 Cancer surface searing apparatus and method of use thereof  
The invention comprises a charged particle cancer therapy system used to seal a periphery of a tumor, such as through use of a proton or carbon ion beam searing the outer edges of the tumor, which...
9682247 Apparatus for the generation of an energy field for the treatment of cancer in body cavities and parts that are cavity-like  
The body cavity cancer treatment apparatus generates the magnetic field for use in a combined “low temperature hyperthermia” and ionizing radiation and/or chemotherapy cancer treatment protocol....
9682090 Methods for treating and preventing prostate cancer bone metastases  
Methods for treating a subject having a prostate cancer bone metastasis are disclosed. Methods for prophylactically treating a subject at risk of developing a prostate cancer bone metastasis are...