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9528982 Bad phosphorylation determines ovarian cancer chemo-sensitivity and patient survival  
Despite initial sensitivity BAD-protein phosphorylation were evaluated in patient samples and cell lines as determinants of chemo-sensitivity and/or clinical outcome, and as therapeutic targets....
9527922 Humanized alpha-enolase specific antibodies and methods of uses in cancer therapy  
A humanized antibody, or a binding fragment thereof, wherein the humanized antibody binds human ENO1 (GenBank: AAH50642.1), wherein the antibody comprises a light chain variable region (VL) domain...
9527919 High affinity anti-prostate stem cell antigen (PSCA) antibodies for cancer targeting and detection  
The present invention provides novel high affinity antibodies and fragments thereof that bind to the cancer antigen PSCA. The antibodies of the present invention may be used for cancer diagnosis,...
9527895 CAPCNA peptide therapeutics for cancer  
Administration of compositions comprising cell-permeable cancer-specific proliferating cell nuclear antigen derived peptides and their variants reduces the proliferation of cancer cells and also...
9526911 Immune mediated cancer cell destruction, systems and methods  
Systems and methods for delivering electric fields to a target tissue of a patient for destruction of cancerous cells so as to elicit or induce a specific anti-cancerous cell immune response in...
9526800 Cancer-related extracellular matrix signatures and related methods and products  
Proteomic methods for identifying cancer related proteins and related products and kits are provided. The cancer specific proteins are extracellular matrix proteins that are associated with...
9526779 Method for cancer immunotherapy and pharmaceutical compositions based on oncolytic non-pathogenic Sendai virus  
The invention relates to the field of immunology and medicine, more specifically, oncology, and can be useful for the treatment of patients with carcinomas and sarcomas. A pharmaceutical...
9526768 Compositions for the treatment of cancer  
The present invention relates to novel compositions comprising proteolytic enzymes and fining agents as well as methods for the treatment and/or prevention of cancer using these compositions.
9526759 Activin-actriia antagonists and uses for treating or preventing breast cancer  
In certain aspects, the present invention provides compositions and methods for treating or preventing breast cancer in humans.
9526709 Compositions and methods for treating cancer  
The present invention provides, in part, compositions and methods for treating cancer using a combination of C6-ceramide and other anti-cancer agents.
9523691 Use of the olfactomedin-4 protein (OLFM4) in colorectal cancer diagnosis  
The present invention provides a method for diagnosing KRAS mutations in colorectal cancers by measuring the level of OLFM4. In another aspect, the present invention relates a method of predicting...
9523689 Treating bladder cancer patients and identifying bladder cancer patients responsive to treatment  
This documents provided methods and materials involved in treating bladder cancer. This document also provides methods and materials involved in identifying bladder cancer patients likely or...
9523688 Diagnosis method and treatment for cancer using liv21 proteins and E2F1/E2F4 biomarkers  
The invention concerns a novel diagnostic and/or prognostic test for cancer. More particularly, the invention concerns the human LIV21 protein, its use as cancer diagnostic and prognostic markers....
9522958 Cancer targeted innate immunity  
Provided is a cancer therapeutic agent comprising a cancer targeting molecule linked to a CpG oligodeoxynucleotide. Also provided are methods of reducing the size of a tumor or inhibiting the...
9522955 Anti-vascular endothelial growth factor receptor-2 chimeric antigen receptors and use of same for the treatment of cancer  
The invention provides chimeric antigen receptors (CARs) comprising an antigen binding domain of a KDR-1121 or DC101 antibody, an extracellular hinge domain, a T cell receptor transmembrane...
9522935 Commands and method of treating cancer via RHO pathway  
Lanosterol derivatives useful as anti-cancer agent, which can inhibit the growth of lung cancer cells, liver cancer cells, mammary cancer cells, brain cancer cells and pancreatic cancer cells,...
9522925 Selective cancer tracking eradicator and the uses thereof  
The present invention discloses a new modality of photodynamic therapy (PDT) through the design of the present invention's truly dual-functional—PDT and imaging—gadolinium complex (Gd—N) with a...
9522909 Thiazolidinedione derivatives, preparation thereof and use thereof in cancer treatment  
The present invention relates to thiazolidinedione derivatives, to the processes for preparing same and to the therapeutic use thereof for preventing or treating cancer, and more specifically...
9522187 Cancer therapy using beta glucan and antibodies  
The present invention relates to methods of using neutral soluble glucan and monoclonal antibodies for antitumor therapy. Neutral soluble Beta (1,3; 1,6) glucan (NSG) enhances the tumoricidal...
9522185 Human antibodies to GFR α3 and methods of treating pain associated with osteoarthritis or bone cancer  
The present invention provides antibodies that bind to human GFRα3 and methods of using same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind...
9522139 Fructose 1, 6-biphosphatases as new targets for diagnosing and treating breast cancer brain metastasis  
A method and composition for treating cancer cells that targets fructose-1,6-biphosphatase (EC:3.1.3.11) enzymes (FBPs, type 1 and type 2) and/or their respective pathways. In one embodiment,...
9522125 Method of treating cancer  
The present invention discloses that a method of treating cancer, preferably non-small cell lung cancer, comprises administrating mitoxantrone. The present invention also discloses a method of...
9521994 System and method for image guided prostate cancer needle biopsy  
In a method for image guided prostate cancer needle biopsy, a first registration is performed to match a first image of a prostate to a second image of the prostate. Third images of the prostate...
9518990 Secernin-1 as a marker for cancer  
Disclosed is a method aiding in the assessment of cancer. It involves the use of the secernin-1 protein (SCRN1) as a universal marker of different cancer types. More specifically disclosed is a...
9518989 Composition and method for diagnosis and immunotherapy of lung cancer  
The present invention includes compositions and methods for the diagnosis and treatment of lung cancer with a recombinant tumor-associated antigen loaded antigen presenting cell that generates a...
9518125 Composition for diagnosing liver cancer and methods of diagnosing liver cancer and obtaining information for diagnosing liver cancer  
Provided is method of diagnosing liver cancer in a subject, the method comprising contacting a sample from a subject with a substance that specifically binds to transmembrane emp24 domain...
9518123 Compositions and methods for treatment of cancer  
The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the...
9518120 Anti-CXCR4 antibody and its use for the detection and diagnosis of cancer  
The present invention provides a novel, isolated anti-CXCR4 antibody for use in the diagnosis of cancer. In particular, the antibody of the invention recognizes monomeric and homodimeric CXCR4,...
9518079 Effective treatment of tumors and cancer with triciribine and related compounds  
The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat tumors and cancer by one or a combination of (i) administering triciribine...
9517258 Methods and materials for treating cancer  
This document provides methods and materials for treating cancer. For example, methods and materials for identifying antigens and combinations of antigens that can be used to treat cancer as well...
9517245 Sorafenib-microRNA combination therapy for liver cancer  
A method of treating a subject having liver cancer can include administering a synthetic oligonucleotide to a subject having liver cancer, the oligonucleotide comprising a sequence that is at...
9517240 Methods and compositions for cancer prevention and treatment  
The present invention provides methods of preventing or delaying the development of cancer (e.g., breast cancer) in BRCA1 mutation positive patients by beginning progesterone receptor antagonist...
9517229 Treatment of breast cancer  
The disclosure describes the use of one or more compounds that fall within the scope of one or more of structural formulae I, II, III, IV, V, or VI for treating triple negative breast Compounds...
9513292 Method for diagnosing cancer by detecting GPC3  
Provided is a method for diagnosing cancer by detecting a novel cancer marker. Cancer can be diagnosed by detecting soluble glypican 3 in a test sample.
9512491 Detection of digestive organ cancer, gastric cancer, colorectal cancer, pancreatic cancer, and biliary tract cancer by gene expression profiling  
The present invention provides a method and a reagent for detecting a digestive organ cancer, gastric cancer, colorectal cancer, pancreatic cancer, or biliary tract cancer patient by analyzing...
9512490 Detection of digestive organ cancer, gastric cancer, colorectal cancer, pancreatic cancer, and biliary tract cancer by gene expression profiling  
The present invention provides a method and a reagent for detecting a digestive organ cancer, gastric cancer, colorectal cancer, pancreatic cancer, or biliary tract cancer patient by analyzing...
9512486 Materials, methods, and systems for treating cancer  
Aspects of the invention relate to methods of treatment, and to kits and systems for the same including materials for determining that an individual is susceptible to cancer and if warranted...
9512485 Methods for predicting anti-cancer response  
The present invention is based, in part, on the identification of novel methods for defining predictive biomarkers of response to anti-cancer drugs.
9512484 Methods for determining a prognosis for survival for a patient with breast cancer  
A method for determining a prognosis for survival for a patient with breast cancer is described. Also described is a method for monitoring the effectiveness of a course of treatment for a patient...
9512464 System and method for detecting of alpha-methylacyl-CoA racemase (AMACR) and prostate cancer  
A detection system for determining alpha-methylacyl-CoA (AMACR) levels in a bodily sample includes at least one reaction solution for generating H2O2 upon combination with AMACR in the bodily...
9512429 Pharmaceutical composition comprising Nanog shRNA, and method of using Nanog shRNA to treat cancer  
The present description relates to an inhibitory RNA molecule, comprising an oligonucleotide that selectively knocks down expression a Nanog pseudogene expressed in many human cancers, a...
9512425 Inhibiting migration of cancer cells  
As described herein, increased expression of microRNA-708 reduces migration and metastasis of cancer cells.
9512234 Methods for treating colon cancer and inflammation associated with overexpression of human signal peptide-containing proteins  
The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies,...
9512232 Antibodies against Claudin 18.2 useful in cancer diagnosis  
The invention relates to antibodies directed against an epitope located within the C-terminal portion of CLDN18.2 which are useful, for example, in diagnosing cancer and/or in determining whether...
9512223 Methods for treatment of gastric cancer  
The application provides methods of detection, diagnosis, prognosis, prophylaxis and treatment of folate receptor-alpha-expressing gastric cancer using antibodies that specifically bind to folate...
9512207 Anti-NPC2 monoclonal antibodies and a method of detecting fatty liver tissue, cancer cells or cancer tissue by using them  
The present invention is related to anti-NPC2 monoclonal antibodies, which against NPC2 or glycosylated-NPC2; and is related to a method of detecting fatty liver tissues, cancer cells or cancer...
9512193 P15 protein variant and use thereof for preventing or treating cancer  
A p15 protein variant; a polynucleotide encoding the p15 protein variant; a method for preparing the p15 protein variant; a pharmaceutical composition comprising the p15 protein variant; and a...
9512138 Compositions and methods for treating cancer  
Provided herein, inter alia, are compositions and methods useful for treating hyperproliferative diseases, including cancer and non-malignant hyperproliferative diseases.
9512086 Compound for promoting apoptosis of cancer cells and a pharmaceutical composition containing the same and uses thereof  
The present invention provides a compound of Formula (I) and a salt thereof, wherein, m is an integer of 2 to 7, and R is independently at least one selected from the group consisting of hydrogen...
9511151 Compositions and methods for the prevention and treatment of cancer  
Conventional cancer immunotherapy falls short at efficiently expanding T cells that specifically target cancerous cells in numbers sufficient to significantly reduce the tumor size or cancerous...