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10392442 Use of anti-PD-1 antibody in combination with anti-CD27 antibody in cancer treatment  
This invention provides methods for treating cancer in a subject comprising administering to the subject an anti-PD-1 antibody and an anti-CD27 antibody. In some embodiments, the cancer is...
10392427 Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC, SCLC and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10392398 Inhibitors of Late SV40 Factor (LSF) as cancer chemotherapeutics  
The present invention is directed to methods, compositions and kits for treatment of cancer, e.g. heptacellular carcinoma. In some embodiments, the present invention discloses the use of a...
10392354 Highly selective anti-cancer agents targeting non-small cell lung cancer and other forms of cancer  
Described herein are analogs of 2-methyl-3-(2-ethynylthiazol-4-yl)cyclopent-2-enol and the corresponding ketone 3-(2-ethynylthiazol-4-yl)-2-methylcyclopent-2-enone, the analogs having terminal...
10391333 Treatment apparatus using proton and ultrasound and method of treating cancer using the same  
Provided are a treatment apparatus using proton and ultrasound and a method for treating cancer using the same. The treatment apparatus includes a proton generator configured to emit a proton beam...
10391177 Methods for treating cancer using 6,8-bis (benzylthio) octanonic acid  
Pharmaceutical formulations containing lipoic acid derivatives and ion pairs thereof are described. The pharmaceutical formulations are useful in the treatment of medical disorders, such as cancer.
10391173 Anti-ar agent and radiation therapy for androgen receptor positive cancer  
Provided herein are compositions, systems, kits, and methods for treating cancer in a subject with androgen receptor positive cancer cells by sensitizing such cancer cells with anti-androgen...
10391159 Methods and materials for treating cancer  
This document provides methods and materials for treating cancer. For example, methods and materials for identifying antigens and combinations of antigens that can be used to treat cancer as well...
10391138 Multidimensional approach for Cancer treatment  
Method of treating/managing Cancer is disclosed in various embodiments herein. The disclosed method includes the use of a combination of formulations and therapies that provide a holistic approach...
10391123 Anticancer nano-silver composition for treatment and prevention of cervical cancer, and preparation method and use thereof  
The present invention provided an anticancer nano-silver composition for the treatment and prevention of cervical cancer. The composition contains nano-silver powder 3-200 mg/kg, carbomer 700-1000...
10391111 Composition for preventing or treating cervical cancer including gypenoside LXXV  
Provided are a pharmaceutical composition for preventing or treating cervical cancer including gypenoside LXXV or a pharmaceutically acceptable salt thereof as an active ingredient, a method of...
10391092 Methods for treating cancer using dihydropyrazino-pyrazine compound combination therapy  
Provided herein are methods for treating or preventing a cancer, comprising administering an effective amount of a Dihydropyrazino-Pyrazine Compound and an effective amount of an androgen receptor...
10391084 Methods and compositions to treat cancer  
Embodiments provided herein relate to methods and compositions for treating cancer. Some embodiments include treating lung cancers and renal cancers.
10391080 Ketorolac for the treatment of cancer  
Methods of treating cancer, including PAR-4 implicated cancers or renal cell carcinoma, using ketorolac are disclosed herein. Ketorolac can be administered as a monotherapy or as part of a...
10391076 Anti-cancer agent comprising aminoacetonitrile compound as active ingredient  
The present invention relates to an anticancer agent having a high safety and a superior anticancer activity, and anticancer agent containing, as an active ingredient, an aminoacetonitrile...
10388403 Analyzing copy number variation in the detection of cancer  
The invention provides a method for determining copy number variations (CNV) of a sequence of interest in a test sample that comprises a mixture of nucleic acids that are known or are suspected to...
10386378 Method of diagnosing prostate cancer by detecting chemical elements  
A method of diagnosing a prostate condition in a subject comprises determining, in a sample obtained from a subject, levels of a plurality of constituents selected from the group consisting of Ca,...
10386370 Use of facilitates chromatin transcription complex (FACT) in cancer  
The present invention relates to, inter alia, measuring of at least one component of the facilitates chromatin transcription complex (FACT) for evaluating a tumor, including, for example,...
10385403 DDR2 mutations in squamous cell lung cancer  
Methods for treating patients with squamous cell lung cancer, including detecting the presence of mutations in the discoidin domain receptor 2 (DDR2) gene.
10385400 Methods and kits for monitoring response to radiation therapies in cancer  
A method of evaluating a cancer cell sample, the method comprising: a. obtaining a cancer cell sample, optionally a breast cancer cell sample or an ovarian cancer cell sample, after the cancer...
10385399 Method for determining clinically relevant hypoxia in cancer  
The present invention provides a method for determining the oxygen status of a cancer of an individual. The method comprise determining the transcriptional expression level of ADM (SEQ ID No:1),...
10385343 Methods and compositions for the treatment of cancer  
Described herein are methods and compositions relating to the treatment of cancer, e.g., breast cancer, using, e.g., aptamer-siRNA chimera molecules.
10385138 Antibodies directed to membrane transporter NaP12b (SLC34A2) and uses thereof in cancer therapy  
The present invention relates generally to the membrane transporter NaPi2b (SLC34A2) as a target for therapy, including immunotherapy, and particularly cancer therapy. The SLC34A2 epitope peptide...
10385129 JAM-C antibodies and methods for treatment of cancer  
A novel method to reduce B-cell lymphoma cell migration to and engraftment of the spleen in patients with JAM-C positive B-cell lymphomas is described. In certain aspects, a method for identifying...
10385109 Peptides and combination of peptides for use in immunotherapy and methods for generating scaffolds for the use against pancreatic cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10385105 Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC, SCLC and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10385072 Gold(III) complexes as anticancer agents and a method of treating cancer  
Gold(III) complexes containing mixed ligands. A method of treating cancer with these complexes is disclosed. The complexes are cytotoxic to prostate, breast, ovarian, and Hodgkin lymphoma cancer...
10383943 Compositions and related methods for the treatment of cancer  
Compositions and methods for the use thereof for the treatment of cancer in a subject in need thereof comprising administering to the subject an effective amount of a composition comprising an...
10383930 Peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers  
A method of treating a patient who has prostate cancer includes administering to said patient a composition containing a population of activated T cells that selectively recognize cells in the...
10383928 Telomerase polypeptide vaccine for treating cancer  
A polypeptide comprising the sequence of SEQ. ID NO. 2, 3, 4, 7 or 8. The polypeptide may have the sequence of an immunogenic fragment thereof comprising at least eight amino acids, wherein the...
10383926 Biological markers useful in cancer immunotherapy  
Methods are disclosed that are based on the finding that serum and plasma levels of eotaxin, MIP1α, and CRP act as important biomarkers that are useful for determining the feasibility in...
10383925 Cancer antigen EEF2  
The present invention provides a method for detecting cancer using a protein expressed in various cancers, and a pharmaceutical composition for the treatment or prevention of such cancer using the...
10383924 Combination immunotherapy compositions against cancer and methods  
Disclosed are immunotherapeutic compositions and the concurrent use of combinations of such compositions for the improved induction of therapeutic immune responses and/or for the prevention,...
10383873 Method and kits for identifying of CDK9 inhibitors for the treatment of cancer  
A method of determining sensitivity to cancer treatment includes the step of determining the presence of overexpression of MYC in a biological sample from a patient suffering from cancer, wherein...
10383823 Liposomal cisplatin compositions for cancer therapy  
The present invention provides a composition for the treatment of cancer including zwitterionic liposomes consisting essentially of: 50-65 mol % of a phosphatidylcholine lipid, 30-45 mol % of...
10380739 Breast cancer detection  
A hybrid detection model may be used for breast cancer detection. A system can identify a region of interest on a received mammogram. The region of interest may have a particular level of grey at...
10380736 MIP determination of solid cancer size and size changes based on contrast enhanced MRI and CT imaging  
Methods of obtaining a suspect nodules' sizes and/or growth rate are provided. In one embodiment, the method begins with at a first time: (i) obtaining a first three dimensional (3D) data set cube...
10380491 System for predicting the recurrence of cancer in a cancer patient  
A system predicts the recurrence of cancer. A first slice of a prostate tissue sample is stained so that luminal epithelial cells and basal epithelial cells are stained different colors. A first...
10379124 Tumor suppressor VSTM2A as a biomarker for colorectal cancer  
The present invention provides a method for diagnosing and determining prognosis of colorectal cancer in a subject by detecting suppressed expression of the VSTM2A gene, which in some cases is due...
10379123 Peptide, antibody thereof, and method of assessing risk of oral cancer by using peptide  
The present application discloses a THLW peptide, an amino acid sequence of which is represented by SEQ ID No. 1. The THLW peptide can be used as a biomarker for diseases, such as oral cancer and...
10379056 Diagnosis of cancer  
A method is provided including obtaining an infrared (IR) spectrum of a blood plasma sample by analyzing the blood plasma sample by infrared spectroscopy, and based on the infrared spectrum,...
10378068 Point mutations in TRK inhibitor-resistant cancer and methods relating to the same  
Provided herein are methods of treating a subject having a cancer, methods of selecting a treatment for a subject having a cancer, methods of selecting a subject having a cancer for a treatment...
10378067 Kit for cancer detection  
The present invention provides a primer set and a kit containing same for analyzing a sequence of an MLH1 DNA, an MLH1 mRNA, and/or a cDNA sequence derived from said MLH1 mRNA of a subject to...
10378066 Molecular diagnostic test for cancer  
Methods and compositions are provided for the identification of a molecular diagnostic test for cancer. The test defines a novel DNA damage repair deficient molecular subtype and enables...
10378064 Analyzing circulating nucleic acids to identify a biomarker representative of cancer presented by a patient population  
CNA biomarkers can include nucleic acid sequences that are present in circulating nucleic acids obtained from circulatory systems of a population known to have cancer, but that are rarely present,...
10378060 ZNF365/ZFP365 biomarker predictive of anti-cancer response  
The present invention is based on the identification of novel biomarkers predictive of response to anti-cancer therapies.
10378058 Diagnostic and therapeutic methods and compositions involving PTEN and breast cancer  
Patients with ErbB2-overexpressing cancers can be given an ErbB2 targeting agent as a therapeutic regimen but not all patients are responsive. The present invention concerns the diagnostic,...
10377811 Peptides, combination of peptides as targets and for use in immunotherapy against gallbladder cancer and cholangiocarcinoma and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10377810 Soluble CD80 as a therapeutic to reverse immune suppression in cancer patients  
The present invention provides for a therapeutic cancer treatment using a soluble CD80 fusion protein that binds to PDL1 and inhibits PDL1-PD1 interactions thereby overcoming PDL1-induced immune...
10377803 Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC, SCLC and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...