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9844574 Cancer treatment using viruses and camptothecins  
Mammalian subjects having a neoplasm are treated with a virus and a camptothecin compound, for example irinotecan or topotecan. The virus is selected from the group consisting of a Newcastle...
9844547 Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases  
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed...
9844540 Combination therapies for treating cancer  
Provided are methods for treating cancer in a patient by administering at least antibiotic selected from the group consisting of clofazimine, rifabutin and clarithromycin, in combination with an...
9844529 Combination therapy for ovarian cancer  
The present invention provides a method of treating ovarian cancer in a mammal in need of such treatment comprising administering an effective amount of a combination of gemcitabine, cisplatin or...
9844334 System and method for intraoperative detection of cancer margins using conformal filters in a dual polarization configuration  
Devices, systems, and methods for distinguishing tissue types are described herein. Such devices and systems may use dual polarization, conformal filters to acquire image data from target tissues...
9840728 SRM assay to indicate cancer therapy  
The current disclosure provides for specific peptides, and derived ionization characteristics of the peptides, from the ALK, Ros, Ron, Ret, TS, and/or FGFR1 proteins that are particularly...
9840712 CD133 aptamers for detection of cancer stem cells  
The present disclosure relates to RNA aptamers and uses thereof, in particular, aptamers which specifically bind to CD133 and which demonstrate superior tumor penetration.
9840711 Methods of treating cancer  
A method of treating cancer is disclosed. The method comprises administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising an agent which induces a...
9840566 Preparations and methods for treating a GD2 positive cancer  
The present invention relates to preparations and methods for treating a GD2 positive cancer by administering a preparation comprising a chimeric or humanized anti-GD2 antibody to a patient,...
9840522 Multi-modal bioprobe for bladder cancer imaging and photodynamic therapy  
The present invention relates to a new generation of PDT agents based on porphyrin-lanthanide complexes with specific functional groups which can specifically localize on particular tumors, and...
9840474 Pyrimidine compounds and use as anti-cervical cancer thereof  
Provided is use of a pyrimidine compound or a pharmaceutically acceptable salt thereof in preparation of an anti-cervical cancer medicament. Research of the present invention has found that the...
9840470 Targeting GLI proteins in human cancer by small molecules  
The present disclosure provides compositions, pharmaceutical preparations and methods for the diagnosis and treatment of cancers expressing a GLI polypeptide. The disclosed compositions and...
9839703 Radiolabeled GRPR-antagonists for diagnostic imaging and treatment of GRPR-positive cancer  
The present invention relates to probes for use in the detection, imaging, diagnosis, targeting, treatment, etc. of cancers expressing the gastrin releasing peptide receptor (GRPR). For example,...
9839688 Combination of rose bengal and systemic immunomodulative therapies for enhanced treatment of cancer  
A method for the treatment of cancer comprising administration of a therapeutically effective amount of an intralesional chemoablative pharmaceutical composition, or variant of said composition,...
9839681 Size tunable microbial mimetics for immunotherapy of cancer  
This invention describes novel immunogenic complexes, which are designed to trigger a robust host immune response against cancer cells by co-opting the immune system's natural ability to eliminate...
9839676 Methods of treating cancer using angiogenin or an angiogenin agonist  
The invention provides a method for treating cancer in a subject or a method of inducing an anti-tumour effect including reducing tumour volume, inhibiting or slowing tumour growth, inhibiting...
9839646 Small molecule enhancer for dendritic cell cancer vaccines  
Disclosed is a method of treating cancer, comprising administering to a mammal in need thereof a therapeutically effective amount of a compound that inhibits a plurality of mammalian DASH serine...
9839638 Compositions and methods for protecting cells during cancer chemotherapy and radiotherapy  
Compositions, pharmaceutical preparations and methods are disclosed for protecting non-neoplastic cells from damage caused by cancer chemotherapeutic agents or radiation therapy, during the course...
9839625 Inhibition of cancer cell motility  
Provided herein are compositions and methods for inhibiting cancer cell motility and/or metastasis. In particular embodiments, KBU2046 (or an analog thereof) and one or more additional therapies...
9839621 Method for treating bladder cancer  
A method for treating bladder cancer including the steps of administering an isothiocyanate functional surfactant to an area affected by bladder cancer, wherein the isothiocyanate functional...
9835636 Serological markers for detecting colorectal cancer and their application for inhibiting colorectal cancer cells  
Embodiments relate to serological markers for detecting the colorectal cancer and applications of the serological markers. A phospholipid scramblase1 (PLSCR1), a stomatin-like protein 2 (STOML2)...
9834575 Cancer therapy  
The present application relates to compositions and methods for treating a proliferative disorder by administering to a subject a pharmaceutical composition of a dual kinase inhibitor metabolite....
9834532 Stat3 pathway inhibitors and cancer stem cell inhibitors  
The present invention relates to a novel naphtho class of compounds as Stat3 pathway inhibitors and as cancer stem cell inhibitors; to methods of using such compounds to treat cancer; to methods...
9833514 Use of pegylated IL-10 to treat cancer  
Provided are methods of treatment for tumors. In particular, methods are provided for use of a chemically modified IL-10 to treat tumors.
9833512 Blocking IL-9 signaling in conjunction with chemotherapy to treat cancer  
This document provides methods and materials related to using inhibitors of IL-9 signaling in conjunction with chemotherapy to treat cancer (e.g., solid tumors). For example, methods and materials...
9833508 Cancer therapeutics  
The invention relates to the treatment of cancer. In one embodiment, the present invention provides a composition comprising a micelle construct attached to a glut-1 antibody and a curcumin...
9833496 Method for identifying, expanding, and removing adult stem cells and cancer stem cells  
The invention relates to the fields of biochemistry, pharmacy and oncology. The invention particularly relates to the use of novel stem cell markers for the isolation of stem cells. The invention...
9833464 Target-aiming drug delivery system for diagnosis and treatment of cancer containing liposome labeled with peptides which specifically targets interleukin-4 receptors, and manufacturing method thereof  
The present invention relates to a target-aiming drug delivery system for diagnosis and treatment of cancer containing liposome labeled with peptides which specifically targets interleukin-4...
9833431 Pharmaceutical combinations for the treatment of cancer  
The present invention relates to pharmaceutical combinations comprising aminoacetonitrile derivatives and anticancer compounds. Further, the present invention relates to these pharmaceutical...
9833422 Anti-cancer activity of (E)-1-(3′,4′-dimethoxyphenyl)butadiene  
The present invention provides a method of using (E)-1-(3′, 4′-dimethoxyphenyl) butadiene to induce anti-tumorigenic effects in pancreatic carcinoma, ovarian carcinoma and prostate carcinoma. The...
9828645 Composition and kit for diagnosing breast cancer including polynucleotide within vesicle, and method of diagnosing breast cancer using the same  
A breast cancer diagnostic composition and kit, and methods of diagnosing breast cancer or acquiring information for breast cancer diagnosis by using the composition or kit are provided. The...
9828604 Phosphodiesterase 9A as prostate cancer marker  
The present invention relates to phosphodiesterase 9A (PDE9A) for use as a marker for prostate cancer, and the use of PDE9A as a marker for diagnosing, detecting, monitoring or prognosticating...
9828432 Cancer treatment and monitoring methods using OX40 agonists  
OX40 is a potent immune stimulating target. Provided herein are methods for the treatment of cancer patients using (3X40 agonists methods to predict clinical outcome of the treatment by...
9828393 Silylalkyloxyaryl compounds and methods for treating cancer  
Silylalkyloxyaryl compounds useful as anti-cancer agents. The compounds and pharmaceutical compositions containing them are particularly useful for the treatment of melanoma, colon, neuroblastoma,...
9827338 GRP-R agonistic 177-lutetium-labeled bombesin derivatives for diagnosis and treatment of prostate cancer  
Provided is a novel compound capable of being usefully used to diagnose and treat prostate cancer by labeling a radioisotope on a bombesin derivatives capable of selectively targeting a target...
9827328 Combination therapy for treatment of cancer  
The present invention relates to methods and compositions for the treatment of cancer. Some embodiments include methods of treating cancer comprising administering a chemotherapeutic agent...
9827325 Drug delivery of temozolomide for systemic based treatment of cancer  
The present invention relates to methods of drug delivery for the treatment of a condition or disease, such as cancer. In one embodiment, the invention provides a method of preparing a...
9827309 Treating cancer with a combination of a PD-1 antagonist and dinaciclib  
The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and the CDK inhibitor dincaciclib, and the use of the combination therapies...
9827288 Method for treating a refractory or relapsed lung cancer  
The present invention relates to a method for treating a refractory or relapsed lung cancer. Particularly, the invention provides a method and a formulation of using an immunomodulatory protein...
9827261 Etoposide and prodrugs thereof for use in targeting cancer stem cells  
The present invention pertains to the use of podophyllotox in derivatives, such as CAP7.1, in methods for inhibition of and/or prevention of the growth and/or survival of cancer stem cells. The...
9827224 Methods and compositions for ameliorating pancreatic cancer  
Embodiments of the present invention include methods and compositions for ameliorating cancer. Some embodiments include methods and compositions for ameliorating pancreatic cancer targeting the...
9822417 Methods and biomarkers for analysis of colorectal cancer  
The present invention relates to methods and biomarkers (e.g., gene expression biomarkers) for detection of colorectal cancer in biological samples (e.g., tissue samples, biopsy samples, stool...
9822416 miRNA in the diagnosis of ovarian cancer  
The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g....
9822363 Replication factor C-40 (RFC40/RFC2) as a prognostic marker and target in estrogen positive and negative and triple negative breast cancer  
The present disclosure relates generally to cancer and particularly to breast cancer including estrogen sensitive, estrogen resistant and triple negative breast cancer (TNBC), and to methods of...
9822202 Polymer/copper combination for targeted cancer therapy  
Polymer/copper combination that can selectively target and kill cancer cells are described. Materials can include the reaction product of a biocompatible hydrophilic polymer and pyridine-2-thiol...
9822174 Anti-VEGF antibody, and pharmaceutical composition for preventing, diagnosing or treating cancer or angiogenesis-related diseases, containing same  
A novel anti-vascular endothelial growth factor (VEGF) antibody having a strong binding affinity for VEGF and capable of inhibiting in vivo tumor growth and a composition for the treatment of...
9822170 Co-use of a clusterin inhibitor with an EGFR inhibitor to treat cancer  
Epidermal growth factor receptor (EGFR) expression and phosphorylation is increased in cancer cells treated with anti-clusterin antibodies. Such treatment is also accompanied with the reappearance...
9822139 Pharmaceutical composition containing cyclometalated N-heterocyclic carbene complexes for cancer treatment  
The present disclosure is related to a pharmaceutical composition for treatment of cancer comprising a cyclometalated N-heterocyclic carbene complex. The cyclometalated N-heterocyclic carbene...
9822111 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer  
The specification generally relates to compounds of Formula (I): and pharmaceutically acceptable salts thereof, where Q, R1, R2, R3, R4 and R5 have any of the meanings defined herein. The...
9822064 Methods of producing cancer treating compounds  
Provided herein are methods of making the compound of Formula I: and certain intermediates involved in such process.