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9642918 Combination of inotuzumab ozogamicin and torisel for the treatment of cancer  
The present invention relates to a therapeutic method for the treatment of cancer that comprises the use of a combination of inotuzumab ozogamicin (CMC-544) and temsirolimus. The enhanced...
9642859 Use of capsazepine and analogs thereof to treat cancer  
Disclosed are methods and compositions for treating cancer, particularly for reducing cancerous cell growth, for example, in solid tumors. Disclosed methods and compositions include capsazepine...
9642856 Treatment for pancreatic cancer  
The invention is related to a method of treating a subject with pancreatic cancer with administration of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt...
9642847 Combinational compositions and methods for treatment of cancer  
The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a...
9642843 Pharmaceutical compounds and use of same in cancer and tauopathies  
Disclosed are compounds of formula (1)-(V): where the substituents are as provided herein. Further disclosed are methods of inhibiting tau aggregation, treating or ameliorating a tauopathy or...
9642827 Method for treating skin cancer  
A method for treating skin cancer including the steps of applying an isothiocyanate functional surfactant to an area affected by skin cancer, wherein the isothiocyanate functional surfactant...
9642821 MiR-182 in the diagnosis and treatment of cancer  
The present disclosure provides methods of determining the levels of BRCA1 in a cell, altering the levels of BRCA1 in a cell, determining the likelihood of developing cancer, and determining the...
9642805 Aptamer-loaded, biocompatible nanoconstructs for nuclear-targeted cancer therapy  
Disclosed herein is a nanoconstruct comprising an aptamer and a gold nanostar. The nanoconstruct can be used in a method of inducing changes to a nuclear phenotype of a cell comprising...
9640375 Method for crystallizing low mass ions for diagnosing colorectal cancer and method for diagnosing colorectal cancer using same  
The present invention provides a method for determining low mass ions for diagnosing colorectal cancer by using a MALDI-TOF mass spectrometer to biostatistically analyze low mass ions, which are...
9638695 Noninvasive detection of lung cancer using exhaled breath  
A non-invasive method of detecting or screening for lung cancer in a subject specimen is provided. The method includes detecting elevated levels of one or more carbonyl-containing volatile organic...
9637798 Genetic signature of vulnerability to inhibitors of base excision repair (BER) in cancer  
The invention relates to the identification of genetic signatures and expression profiles that are a part of the Base Excision Repair (BER) pathway, a major DNA repair pathway that modifies base...
9637793 Pancreatic cancer markers, and detecting methods, kits, biochips thereof  
The present invention provides microRNAs for assessing the status of pancreatic cancer in a subject, and provides methods, kits, and biochips for detecting said microRNAs.
9637740 Cancer treatment and immune system regulation through FAT10 pathway inhibition  
Described herein are methods of inhibiting mitosis, treating cancer and/or treating immune disorders through the use of agents that inhibit FAT 10 and/or the FAT 10 pathway.
9637722 Production method of polyurethane porous membrane to be used for at least one of applications of cell culture and cancer cell growth inhibition  
A polyurethane porous membrane is produced by a simple method to be used for at least one of applications of cell culture and cancer cell growth inhibition. The production method of the...
9637554 Bruton's tyrosine kinase as anti-cancer drug target  
Receptor protein kinases (RPTKs) transmit extracellular signals across the plasma membrane to cytosolic proteins, stimulating formation of complexes that regulate key cellular functions. Over half...
9637548 Methods and compositions for diagnosis and treatment of cancer  
The present invention relates to the identification of nucleic acid and amino acid sequences that are characteristic of colorectal, in particular colonic, and gastric tumor tissues and colorectal,...
9637475 Compounds for treating cancer  
A method of preventing, inhibiting, or treating cancer that includes contacting a cell with at least one compound of formula (Ia) or a pharmaceutically acceptable salt thereof: where: R...
9637448 Resveratrol selenide preparation for treating cancer  
A trans-resveratrol selenide for treating cancer has such a structure as: wherein hydroxyls at position 3, 4 and 5 are replaceable, at least one hydroxyl at position 3, 4, 5 is replaced with R, R...
9636406 Method of treating cancer  
The invention provides a method for treating cancer using a coadministration strategy that combines local codelivery of a therapeutic agent and an intracellular penetration enhancing agent, and...
9636404 Pharmaceutical composition comprising modified hemoglobin-based therapeutic agent for cancer targeting treatment and diagnostic imaging  
The present invention provides a pharmaceutical composition containing hemoglobin-based therapeutic agent for treating cancer. The hemoglobin moiety can target cancer cells and the therapeutic...
9636388 Multi-indication mRNA cancer immunotherapy  
Synthetic bacterial messenger RNA can be used to prepare autologous, allogenic or direct nucleic acid cancer vaccines. Cancer cells are transfected either in vitro or in vivo with mRNA obtained...
9636359 Pharmaceutical composition for treating cancer comprising trypsinogen and/or chymotrypsinogen and an active agent selected from a selenium compound, a vanilloid compound and a cytoplasmic glycolysis reduction agent  
The present invention generally relates to pharmaceutical compositions containing a protease proenzyme and use thereof for treating cancer. The pharmaceutical compositions are directed to...
9636342 Method for treating prostate cancer  
The invention provides a method for treating prostate cancer in a subject comprising administering to the subject an effective amount of a selective inhibitor of one or more of CDK8 and CDK19. In...
9636329 Methods of treating cancer with glut inhibitors and oxidative phosphorylation inhibitors  
Disclosed herein are methods of treating, diagnosing, and prognosing GLUT-dependent cancers and OXPHOS-dependent cancers. In some embodiments, the methods comprise administering to a patient in...
9636323 Method of treating cancer that overexpresses TopBP1  
The present invention provides a method of treating cancer that overexpresses TopBP1 by administering to a patient suffering from the cancer with an effective amount of a small molecule inhibitor...
9636320 Method for treating skin cancer  
A method for treating skin cancer including the steps of applying an isothiocyanate functional surfactant to an area affected by skin cancer, wherein the isothiocyanate functional surfactant...
9636075 Simulation-based estimation of elasticity parameters and use of same for non-invasive cancer detection and cancer staging  
Simulation-based estimation of elasticity parameters and use of same for non-invasive cancer detection and cancer staging are disclosed. According to one aspect, a method for simulation-based...
RE46379 Functional immunohistochemical cell cycle analysis as a prognostic indicator for cancer  
The present invention relates to a method of determining the presence of a retinoblastoma protein (Rb)-mediated cancerous or pre-cancerous condition in a sample of fixed cells that involves...
9632091 Compositions and methods for prostate cancer analysis  
The invention provides methods for diagnosing prostate cancer. The invention also provides novel anti-STEAP-1 antibodies and uses thereof.
9632074 Compositions and methods for treating cancer and diseases and conditions responsive to cell growth inhibition  
In alternative embodiments, the invention provides compositions and methods for overcoming or diminishing or preventing Growth Factor Inhibitor resistance in a cell, or, a method for increasing...
9631241 Complex sets of miRNAs as non-invasive biomarkers for colon cancer  
Described herein are non-invasive methods, kits and means for diagnosing and/or prognosing of colon cancer a body fluid sample from a subject. Further described herein are sets of polynucleotides...
9631239 Method of classifying a breast cancer instrinsic subtype  
Methods for classifying and for evaluating the prognosis of a subject having breast cancer are provided. The methods include prediction of breast cancer subtype using a supervised algorithm...
9631013 Therapeutic method for pancreatic cancer  
The present invention relates to methods and medicarnents useful for treating locally advanced pancreatic cancer (LAPC). Improved therapeutic methods and regimens comprising anti-connective tissue...
9630966 Treatment of cancer with dihydropyrazino-pyrazines  
Provided herein are methods for treating or preventing glioblastoma multiforme (GBM) characterized by O6-methylguanine-DNA methyltransferase (MGMT) expression and/or promoter methylation status,...
9629919 Drug delivery of temozolomide for systemic based treatment of cancer  
The present invention relates to methods of drug delivery for the treatment of a condition or disease, such as cancer. In one embodiment, the invention provides a method of preparing a...
9629385 Dietary composition containing cistanche deserticola polysaccharide with inhibitory effects on colon cancer  
The use of a Cistanche deserticola polysaccharide in the preparation of food supplement having the efficacy of inhibiting colon cancer, wherein Cistanche deserticola polysaccharide is prepared by...
9625461 Method of detecting cancer using delta-catenin  
The present invention provides a method for detecting or screening for the presence of cancer in a subject. The method comprises obtaining, providing or collecting a tissue or fluid sample (such...
9624549 Stable gene targets in breast cancer and use thereof for optimizing therapy  
A method for determining genes in breast cancer that are stable in copy number, expression and sequence in tumors from nearly all patients. Certain stable genes are targets of standard...
9624548 Methods for diagnosing cancer  
Described are bladder cancer specific biomarkers and lung cancer specific biomarkers comprising the nucleic acid sequence of the Engrailed-2 (EN2) gene or the amino acid sequence of the encoded...
9624547 Salivary transcriptomic and proteomic biomarkers for breast cancer detection  
Presented herein are biomarkers related to breast cancer. The presently identified salivary biomarkers create the basis for a breast cancer detection bioassay with sensitivity and specificity....
9624511 Specific TT virus sequences and chimeric TT virus host cell DNA molecules for use in diagnosis, prevention and treatment of cancer and autoimmunity  
Described are single-stranded new sequences of TT viruses, rearranged TTV sequences and hybrid molecules of a specific TT virus sequence and host cell DNA that are capable of replicating...
9624491 Methods and compositions for the detection and treatment of cancer involving miRNAs and miRNA inhibitors and targets  
The present invention relates to microRNAs (miRNAs) which are associated with cancer, particularly including hematologic malignancies, and particularly T-cell acute lymphoblastic leukemia (T-ALL),...
9624306 Anti-epidermal growth factor receptor variant III chimeric antigen receptors and use of same for the treatment of cancer  
The invention provides chimeric antigen receptors (CARs) comprising an antigen binding domain of human antibody 139, an extracellular hinge domain, a transmembrane domain, and an intracellular...
9624284 Cytotoxic T lymphocyte inducing immunogens for prevention treatment and diagnosis of cancer  
The present invention relates to compositions and methods for the prevention, treatment, and diagnosis of cancer, especially carcinomas, such as pancreatic carcinoma. The invention discloses...
9624211 Anti-cancer compounds  
Provided are methods and compositions for the treatment of diseases such as cancer. In certain aspects, compounds which can inhibit Skp2 are provided. Specifically chromenone derivatives are...
9623128 Compositions and methods for detecting plectin-1 as a biomarker for cancer  
The present invention provides compositions and methods useful for diagnostic and imaging techniques for detecting and localizing the biomarker Plectin-1. The present invention provides multimeric...
9623124 Multimodal diagnostic technology for early stage cancer lesions  
Disclosed herein are compositions of a multimodal detection agent and methods of fabricating the same. The multimodal detection agent comprises a plurality of metallic nanoparticles attached to a...
9623116 Antibody-light fusion products for cancer therapeutics  
Antibody-LIGHT fusion products or conjugates stimulate immunity against tumors and eradicate metastases. Tumor-specific antibodies coupled with LIGHT effectively target metastatic tumors and...
9623109 Methods of killing cells and use of same in prevention and treatment of cancer  
A method of killing a cell having a mutation in an Adenomatous polyposis coli (APC) gene is disclosed. The method comprises contacting the cell with an inhibitor of Casein kinase I (CKI), the CKI...
9623079 Methods for achieving therapeutically effective doses of anti-CD47 agents for treating cancer  
Methods are provided for treating a subject with a therapeutic dose of anti-CD47 agent by administering a primer agent prior to administering a therapeutically effective dose of an anti-CD47 agent...