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9803017 Soluble MIC neutralizing monoclonal antibody for treating cancer  
Disclosed are compositions and methods relating to antibodies that bind soluble Major Histocompatibility Complex class I chain-related (sMIC). Specifically, disclosed are antibodies designed or...
9803014 JAM-C antibodies and methods for treatment of cancer  
A novel method to reduce B-cell lymphoma cell migration to and engraftment of the spleen in patients with JAM-C positive B-cell lymphomas is described. In certain aspects, a method for identifying...
9802998 Short peptide-based therapeutic agent and medicinal composition including the same for inhibiting activities of cancer cells  
The present invention relates to a short peptide-based therapeutic agent and a medicinal composition including the same for inhibiting activities of cancer cells, which includes at least one short...
9802948 Inhibitors of late SV40 factor (LSF) as cancer chemotherapeutics  
The present invention is directed to methods, compositions and kits for treatment of cancer, e.g. heptacellular carcinoma. In some embodiments, the present invention discloses the use of a...
9801922 Compositions and methods of treating cancer  
The invention provides compositions and methods to treat cancer with an agent that increases reactive oxygen species (ROS) levels in cancer cell mitochondria (“an XTPP agent”) or a...
9801903 Targeting cancer with metabolic therapy and hyperbaric oxygen  
A method of treating cancer using ketogenic diet, while concurrently subjecting the patient to a hyperbaric, oxygen-enriched environment. Optionally, the hyperbaric, oxygen-enriched environment is...
9801898 Glutamate dehydrogenase 1 inhibitors and methods of treating cancer  
This disclosure relates to methods of treating or preventing cancer comprising administering an effective amount of a glutamate dehydrogenase 1 inhibitor to a subject in need thereof. In certain...
9801893 Method of treatment for prostate cancer with androgen receptor antagonists and glucocorticoid receptor antagonists  
Methods are directed to the treatment of subjects with prostate cancer, in particular those with castration resistant prostate cancer, with glucocorticoid receptor antagonists. The prostate cancer...
9801873 Methods for treating humans having brain cancer  
Among other things, a method of treating a human having brain cancer is, the method comprising administering via a non-continuous dosing regimen to the human having brain cancer, a therapeutically...
9801854 Slow release formulations of cell cycle regulators and anti-cancer agents for local treatment of solid cancer  
Provided herein are methods for treating cancer of a body cavity, including specifically urinary tract cancer, by way of at least one cell cycle regulator, and at least one anti-cancer drug for...
9801844 Methods and compositions for the treatment of cancer  
The invention provides compositions with low toxicity and high bioavailability for treating cancer or for inhibiting the development of cancer.
9797907 Isolation, detection, diagnosis and/or characterization of circulating Trop-2-positive cancer cells  
Described herein are compositions and methods of use of anti-Trop-2 antibodies or antigen-binding fragment thereof to isolate, enrich, detect, diagnose and/or characterize circulating tumor cells...
9797906 Detectors of serum biomarkers for predicting ovarian cancer recurrence  
Polypeptide marker antigens for detecting the presence of autoantibody biomarkers associated with ovarian cancer recurrence, each of the polypeptide marker antigens binding specifically to at...
9797905 Use of markers in the diagnosis and treatment of prostate cancer  
The invention provides method for diagnosis, monitoring, and prognosis of prostate cancer using one or more of keratin 4, keratin 7, keratin 8, keratin 15, keratin 18, keratin 19, tubulin-beta 3,...
9797020 Assay for the detection of avian leukosis/sarcoma viruses (ALSV)-induced cancer or infection in DNA from human and animal biological specimens  
A method of testing a subject for a propensity to develop, diagnose, or treat ALSV-induced infection or cancer, comprising the steps of obtaining a cell, tissue, or fluid sample from the subject,...
9797017 Diagnosis kit and chip for bladder cancer using bladder cancer specific methylation marker gene  
The present invention relates to a kit and nucleic acid chip for diagnosing bladder cancer using a bladder cancer-specific marker gene. More particularly, the invention relates to a kit and...
9797016 Methods and biomarkers for detection of bladder cancer  
The invention relates to methods and biomarkers (e.g., epigenetic biomarkers) for detection of bladder cancer in biological samples (e.g., tissue samples, urine samples, urine sediments). In some...
9796775 Method for detecting pancreatic cancer  
This invention relates to a method for detecting pancreatic cancer using novel tumor markers. Specifically, the invention provides a method for detecting pancreatic cancer comprising measuring the...
9796734 Gold(III) anti-cancer agents  
A method for treating cancer and gold(III) complexes with diaminocyclohexane ligand as anticancer agents. Also described are a pharmaceutical composition incorporating the gold(III) complexes and...
9795696 CEACAM1 based cancer therapy and diagnosis  
The present invention provides methods for detecting CEACAM1 expression in a cancer patient. In particular, methods according to the present invention include contacting a biological sample having...
9795641 Salmonella strains for use in the treatment and/or prevention of cancer  
The present invention relates to a pharmaceutical composition comprising a live attenuated non-recombinant mutant of Salmonella enterica serovar typhi strain and/or a non-viable attenuated...
9795634 Drug delivery systems and methods for treating cancer using gold nanoparticles coated with citrate ions, frankincense and myrrh  
The present disclosure generally pertains to systems and methods for the treatment of cancer. Disclosed herein are compositions for the treatment of cancer, such compositions comprising a...
9795632 Cancer treatments and compositions for use thereof  
The present invention generally relates to compositions and methods for treatment of subjects having or at risk of cancer or other conditions. In some cases, the composition may include nitric...
9795626 Cancer therapy using miRNAs  
The present invention relates generally to methods and compositions for the treatment of cancers expressing the type 1 insulin-like growth factor receptor (IGF1R) or a constituent of an IGF1R...
9795606 Pyrrolopyrimidine compounds for the treatment of cancer  
Compounds of Formula I: wherein: one of X and X′ is N and the other of X and X′ is C, are described, along with compositions containing the same and methods of use thereof in the treatment of cancer.
9795601 Compositions and methods for cancer treatment  
The invention described herein pertains to the use of oxazolidinone antibiotics, alone or in combination, in the treatment of cancer. In particular, the invention pertains to the treatment of...
9795595 Methods for treating cancer  
The invention provides thiazole-substituted indolin-2-ones as inhibitors of cancer stem cell pathway kinases (CSCPK) and related kinases, and methods of using these compounds, to treat subjects in...
RE46572 Plasma biomarker tool for the diagnosis of liver cancer comprising liver carboxylesterase 1 and liver cancer screening method  
The present invention relates to a plasma biomarker for diagnosing hepatocellular carcinoma (HCC), in particular to the discovery of a protein in plasma using 2-D fluorescence differential gel...
9791449 Ovarian cancer stem cells and methods of isolation and uses thereof  
The present invention generally relates to methods, assays, compositions and kits related to a subpopulation of ovarian cancer stem cells which are selected or enriched by chemotherapeutic agents...
9791448 Breast cancer assay  
The application describes a method of screening for breast cancer by testing fro the amount of HAGE (Helicase antigen) in a sample of breast tissue. Methods of prognosis of samples of breast...
9791444 Method for differentially quantifying naturally processed HLA-restricted peptides for cancer, autoimmune and infectious diseases immunotherapy development  
The invention relates to a method for quantitatively identifying relevant HLA-bound peptide antigens from primary tissue specimens on a large scale without labeling approaches. This method can not...
9791443 Method for differentially quantifying naturally processed HLA-restricted peptides for cancer, autoimmune and infectious diseases immunotherapy development  
The invention relates to a method for quantitatively identifying relevant HLA-bound peptide antigens from primary tissue specimens on a large scale without labeling approaches. This method can not...
9790563 Method for treating liver cancer  
The invention discloses a method for evaluating therapeutic effects of lapatinib on liver cancer comprising: obtaining a liver cancer biopsy from a patient; determining level of a biomarker in the...
9790558 Method and probe set for detecting cancer  
Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected...
9790557 Methods and systems for determining a likelihood of adverse prostate cancer pathology  
The present disclosure provides methods that find use in determining a likelihood of adverse prostate cancer pathology in a subject. The methods generally involve detection of one or more...
9790556 Signature for the diagnosis of lung cancer aggressiveness and genetic instability  
The present invention relates to a method for diagnosing aggressiveness of a lung cancer in a patient from a lung cancer sample of the patient, comprising: a) detecting in vitro an expression...
9790555 Marker genes for prostate cancer classification  
The present invention relates to a method for classifying a prostate cancer in a subject, the method comprising the steps of a) determining a gene expression level or gene expression pattern of...
9790554 Complex sets of miRNAs as non-invasive biomarkers for kidney cancer  
The present invention relates to non-invasive methods, kits and means for diagnosing and/or prognosing of kidney cancer in a body fluid sample from a subject. Further, the present invention...
9790518 Furin-knockdown and GM-CSF-augmented (FANG) cancer vaccine  
Compositions and methods for cancer treatment are disclosed herein. More specifically, the present invention describes an autologous cancer vaccine genetically modified for Furin knockdown and...
9790507 Aptamers and use of the aptamers in the diagnosis and treatment of cancer  
The present invention relates to an aptamer comprising a nucleotide sequence SEQ ID NO: 1, a composition comprising an aptamer, and the use of the aptamer in the diagnosis and treatment of cancer,...
9790503 VHZ for diagnosis and treatment of cancer  
We provide VHZ for use in a method of treatment, prophylaxis or alleviation of a cancer, such as breast cancer, in an individual. We provide an anti-VHZ agent for the treatment, prophylaxis or...
9790500 Dual targeting antisense oligonucleotides as apoptotic inhibtor therapeutic compostions and methods for their use in the treatment of cancer  
Provided herein are compositions, method and uses for modulating IAP activity or for the treatment of cancer. The compositions comprise dual-targeting antisense oligonucleotides (dASO) for...
9790492 Agent for treating cancer  
[Problem] To provide the following: an agent for treating cancer, particularly an agent for inhibiting cancer cell proliferation or an agent for inhibiting or preventing cancer metastasis; drug...
9790274 Monoclonal antibodies targeting EpCAM for detection of prostate cancer lymph node metastases  
Embodiments of the invention provide high affinity recombinant EpCAM-binding antibodies. Methods of using a such antibodies as imaging agents, diagnostics and therapeutics are also provided....
9789202 Method for treating cancer using an interferon alpha conjugate  
A method for preventing or treating a cancer includes administering an anti-cancer pharmaceutical composition including an interferon alpha or a polymer conjugate thereof. The pharmaceutical...
9789193 Compositions for treating cancer and methods for making the same  
Described herein are compositions and methods relating to chemotherapeutic agent conjugates and the treatment of cancer.
9789182 Combination of anti-KIR and anti-CTLA-4 antibodies to treat cancer  
Provided are methods for clinical treatment of cancer (e.g., solid tumors or hematological malignancies) using an anti-KIR antibody in combination with an anti-CTLA-4 antibody.
9789173 Vaccine immunotherapy for treating cervical cancer in immune suppressed patients  
A method for overcoming mild to moderate immune suppression includes the steps of inducing production of naive T-cells and restoring T-cell immunity. A method of vaccine immunotherapy includes the...
9789171 Anti-fugetactic agents for the treatment of ovarian cancer  
This invention provides methods and compositions for modulating movement of eukaryotic cells with migratory capacity. More specifically, the invention provides anti-fugetactic agents and methods...
9789170 Arginine deiminase with reduced cross-reactivity toward ADI-PEG 20 antibodies for cancer treatment  
The present invention relates generally to isolated to arginine deiminase (ADI) proteins that have reduced cross-reactivity with anti-ADI-PEG 20 antibodies as compared to ADI-PEG 20, but which can...