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9889159 Peptides and combination of peptides for use in immunotherapy against epithelial ovarian cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
9889155 Enhancer of anti-tumor effect of anti-cancer agent  
An object of the present invention is to provide an agent that potentiates the antitumor effect of an anticancer agent by allowing efficient accumulation of the anticancer agent in tumor tissue....
9889141 Combined inhibition of the vitamin D receptor and poly(ADP) ribose polymerase (PARP) in the treatment of cancer  
Methods for treating tumors comprise contacting tumor cells expressing the vitamin D receptor with a vitamin D receptor ligand that inhibits homologous recombination in the tumor cells, and...
9889138 Method for treating cancer  
The present invention provides a method for treating or alleviating a symptom of a disorder, e.g., immune evasion, cancer-cell induced immune dysfunction, reduced immune response, lowered...
9889120 Combination drug therapies for cancer and methods of making and using them  
In alternative embodiments, provided are therapeutic combinations, pharmaceutical compositions, formulations, kits and devices for treating, preventing or ameliorating a tumor or a cancer, and...
9889105 In vivo method for treating, inhibiting, and/or prophylaxis of cancer, such as pancreatic cancer  
An in vivo method of inhibiting tumor growth, specifically pancreatic cancer, includes administering to a subject in need thereof an effective amount of a compound, composition, and/or a...
9889101 Therapeutic treatment of cancer and dysplasia of the cervix or vagina using estrogen antagonists  
A method for treatment of cervical or vaginal cancer and their associated dysplasia, including the steps of identifying a human cervical or vaginal cancer and/or dysplasia patient, administering...
9889092 Low density lipoprotein nanocarriers for targeted delivery of omega-3 polyunsaturated fatty acids to cancer  
An LDL nanocarrier is an effective and appropriate transporter for DHA in biological systems. The LDL-DHA nanoparticle was shown to be preferentially cytotoxic to malignant liver cells. These...
9889082 Methods and compositions for inhibiting or reducing hair loss, acne, rosacea, prostate cancer, and BPH  
This invention provides methods of treating androgenetic alopecia (AGA), acne, rosacea, prostate cancer, and benign prostatic hypertrophy (BPH), comprising the step of contacting a subject with a...
9885720 Methods for detecting and treating cancer  
The invention generally features compositions and methods for the diagnosis, treatment, and monitoring of neoplasia in a subject, as well as methods of treatment selection.
9885719 Composition comprising lysophosphatidylcholine and homocysteic acid for ovarian cancer diagnosis and method using the same  
Provided are methods of treating a subject for of ovarian cancer, the method including using lysophosphatidylcholine (16:0) and homocysteic acid, which are low-mass ions present in biological...
9885718 Specific biomarker set for non-invasive diagnosis of liver cancer  
Cells within liver tumour mass comprise a unique set of proteins/tumour antigens when compared to the normal liver tissues epithelial cells juxtaposed to the tumour. The presence of tumour...
9885704 Reagents and methods for cancer treatment and prevention  
The invention generally relates to the prevention and/or treatment of cancer, and, more specifically, to the treatment of tumors, including solid tumors and their metastases, without radiation or...
9885044 Polynucleotides and methods for inhibiting cancer cells  
The present invention provides methods of inhibiting or reducing the growth of cancer cells in a subject, by administering a therapeutic effective amount of Puf-A inhibitor, whereby the symptoms...
9885031 Galvanotaxis assay for quantitative assessment of the metastatic potential of cancer cells  
An apparatus and method for accelerating and/or inhibiting the migration of cells by applying a time-varying magnetic field to induce eddy currents that promote electrotaxis (galvanotaxis) of...
9884874 Bromodomain-inhibiting compounds and pharmaceutical composition comprising same for preventing or treating a cancer  
Provided is a novel compound having bromodomain and extra terminal domain (BET) protein inhibiting activities, and a pharmaceutical composition comprising the same which can be useful for...
9884098 Multivalent breast cancer vaccine  
Compositions and methods for immunization against human breast cancer are disclosed. In one embodiment the multivalent antigenic composition is provided comprising immunogenic polypeptides...
9884054 Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer  
Described herein are methods of treating non-metastatic castrate-resistant prostate cancer with anti-androgens.
9884051 Demethylpenclomedine analogs and their use as anti-cancer agents  
This disclosure concerns novel demethylpenclomedine analogs. Also disclosed are pharmaceutical compositions and methods for using such compositions to treat hyperproliferative disorders. In one...
9884047 Method of treating lung cancer  
One example embodiment relates to a method of treating non-small cell lung cancer by administering a compound of formula (I) to a patient. Another example embodiment relates to a method of...
9884046 Method of treating lung cancer  
One embodiment relates to a method of treating lung cancer by administering a compound of formula I to a patient. Another embodiment relates to a method of treating cancer with a KRAS mutation...
9884040 Desethylamiodarone for use in cancer treatment  
The invention relates to a compound selected from the group consisting of desethylamiodarone and pharmaceutically acceptable salts, hydrates and solvates thereof, as well as pharmaceutical...
9884028 Methods for treatment of bladder cancer  
Apparatus and methods for treatment of an internal cavity are provided. The internal cavity is coated with a treatment solution. The treatment solution can include a solidifiable matrix with or...
9881371 System for visualization of a cancer diagnosis  
Certain aspects of an apparatus and method for automatic ER/PR scoring of tissue samples may include for determining a cancer diagnosis score comprising identifying a positive stained nucleus in a...
9879324 Genetic determinants of prostate and breast cancer risk  
Described are methods of determining if a subject has a genetic predisposition to developing prostate cancer (PCa) or aggressive PCa, or to developing breast cancer (BrCa).
9879227 Diffusible factors and cancer cells  
The present invention relates to modified cancer cells that are defective in the production of diffusible factors (e.g., growth factors), and to the use of such cells for impairing the growth of a...
9878998 Barbiturate and thiobarbiturate compounds for use in cancer therapy  
Provided are methods and compositions for use in therapy, and in particular for treating cancer, preferably drug-resistant cancer, and/or radiation resistant cancer. The compounds may be used for...
9878993 DNA-PK inhibitors for treatment of cancer  
The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the...
9878984 Anti-cancer compounds  
The present invention relates to anti-cancer compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides analogs of the known anti-cancer...
9878174 High frequency cancer thermotherapy apparatus  
A high frequency cancer thermotherapy apparatus treats by generating a high frequency electric field between a pair of electrode parts which sandwich a patient and are disposed so as to be...
9878049 High drug loading system to co-deliver anticancer drugs and nucleic acids for cancer therapy  
A high drug loading system is described comprising of at least one anticancer drug; at least one peptide; and at least one nucleic acid.
9878015 Pharmaceutical compositions and methods for the treatment of metastatic cancer  
The invention provides isolated peptides, fragments and derivatives thereof and pharmaceutical compositions comprising same that are useful for the prevention or treatment of cancer metastasis.
9877999 Methods for treating metastatic stage prostate cancer  
The invention provides methods and dosing regimens for eating metastatic stage prostate cancer in a subject using degarelix, as well as related methods of using degarelix in a subject identified...
9877981 NAD biosynthesis and precursors for the treatment and prevention of cancer and proliferation  
Disclosed herein are novel compositions and methods for the treatment of age-related diseases, mitochondrial diseases, the improvement of stress resistance, the improvement of resistance to...
9877978 Compositions comprising NDGA derivatives and sorafenib and their use in treatment of cancer  
The present invention provides pharmaceutical compositions comprising derivatives of NDGA, including M4N (tetra-O-methyl nordihydroguaiaretic acid) and sorafenib and their use in the inhibition...
9877962 Piperazinyl derivatives for the treatment of cancer  
Piperazinyl derivatives of formula (I) and their use as a drug, particularly for the treatment of cancer, are disclosed. Also disclosed are pharmaceutical compositions comprising the piperazinyl...
9877958 Apoptosis-induced agents for the treatment of cancer and immune and autoimmune diseases  
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed...
9877944 Use of a composition comprising fish oil and juice for the treatment and/or post treatment of cancer  
Disclosed is a composition including a fish oil and a juice in an oil-in-water emulsion for use in treatment and post-treatment of cancer.
9873916 Method for predicting response to trastuzumab therapy in breast cancer patients  
This invention relates to a composition and a method for prediction of a response to Trastuzumab therapy in a breast cancer patient, and more specifically, a composition, a kit, a DNA chip, and a...
9873915 Grading, staging and prognosing cancer using osteopontin-C  
The present disclosure provides methods and kits that can be used to determine the grade or stage of a breast or other cancer, such as a ductal carcinoma in situ (DCIS). By determining the grade,...
9873878 Compositions and methods for use in treating silicosis and lung cancer  
A method for treating an inflammatory disease is provided. The method comprises administering an effective amount of a BLT1 inhibitor to a subject in need thereof. The BLT1 inhibitor is selected...
9873876 Cancer treatment  
In certain embodiments, methods, compounds, and compositions for treating B-cell lymphoma or hepatocellular carcinoma by inhibiting expression of ST AT3 mRNA or protein in an animal are provided...
9873747 Fusion proteins that facilitate cancer cell destruction  
Provided is a fusion protein comprising a polypeptide component that blocks binding of CD47 to SIRP alpha and a polypeptide that binds to and triggers a TRAIL receptor or Fas. Also provided is a...
9873740 Methods of treating cancer using PD-1 axis binding antagonists and TIGIT inhibitors  
The present invention describes combination treatment comprising a PD-1 axis binding antagonist and an agent that decreases or inhibits TIGIT expression and/or activity and methods for use...
9873718 Structure-based peptide inhibitors of P53 aggregation as a new approach to cancer therapeutics  
This invention relates, e.g., to an inhibitory peptide or CPP inhibitor which specifically binds to p53 having an aberrant conformation (e.g., is aggregated or misfolded) and inhibits p53...
9873711 Multimeric dual-modality breast cancer diagnostic agents  
The present invention describes dual-modality probes. In particular, the present invention discloses hydroxyapatite specific multimeric bisphosphonate dual-modality MRI and optical probes.
9873699 Anti-cancer agents  
An anti-cancer agent having the formula: wherein Ph is a phenyl group and Ar is an aromatic group independently selected from the group consisting of phenyl, 2-bromophenyl, 4-bromophenyl,...
9873670 Arylquinoline and analog compounds and use thereof to treat cancer  
The subject technology relates to arylquinoline compounds and their use for treating cancer or cancer metastasis. The compounds of the subject technology promote cells to secrete a pro-apoptotic...
9872928 Diagnostic agent for therapeutic effect on cancer  
The present invention provides a diagnostic agent for a therapeutic effect on cancer, containing a compound represented by formula (1-0). (In formula (1-0), R represents ā€”O(CH2)nā€”, ā€”O(CH2)nOC2H4ā€”,...
9872925 Vitamin B6-coupled poly(ester amine) as gene carrier and application in cancer gene therapy  
The present invention relates to a vitamin B6-coupled poly(ester amine) (VBPEA) as a gene carrier and a method for preparing the gene carrier. Moreover, the present invention relates to a gene...