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9551035 Means and methods for diagnosing pancreatic cancer  
The present invention pertains to the field of cancer diagnosis. Specifically, it relates to a method for diagnosing pancreas cancer in a subject comprising the steps of determining in a sample of...
9551034 Method to use gene expression to determine likelihood of clinical outcome of renal cancer  
The present disclosure provides gene and gene sets, the expression of which is important in the classification and/or prognosis of cancer, in particular of renal cell carcinoma.
9550828 Oncostatin M (OSM) antagonists for preventing cancer metastasis and IL-6 related disorders  
A method of treating cancer or metastasis is provided involving administering at least one oncostatin M (OSM) antagonist to a subject, wherein the subject has been diagnosed with cancer....
9550816 Syndecan peptides and polypeptides as inhibitors of cancer  
The invention provides for peptides from syndecan 4 and methods of use therefor. These peptides can inhibit α6β4 integrin interaction with EGFR, thereby preventing tumor cell growth and tissue...
9549922 Use of eribulin and lenvatinib as combination therapy for treatment of cancer  
The invention provides methods and compositions for use in treating diseases associated with excessive cellular proliferation, such as cancer.
9546367 siRNA compositions and methods for inhibiting gene expression in tumor initiating cells of breast cancer  
Disclosed are methods and compositions for siRNA-mediated therapy of mammalian diseases. In particular, compositions and methods are disclosed for treatment of therapy-resistant human breast...
9546366 Replication factor C-40 (RFC40/RFC2) as a prognostic marker and target in estrogen positive and negative and triple negative breast cancer  
The present disclosure relates generally to cancer and particularly to breast cancer including estrogen sensitive, estrogen resistant and triple negative breast cancer (TNBC), and to methods of...
9546365 MicroRNA-198 as a tumor suppressor in ovarian cancer  
A novel network of tumorigenic prognostic factors is identified that plays a critical role in advanced pancreatic cancer (PC) pathogenesis. This interactome is interconnected through a central...
9546354 Z cells activated by zinc finger-like protein and uses thereof in cancer treatment  
Immune cells (Z cells) activated by zinc finger-like protein that regulates apoptosis (Zfra) and uses thereof in cancer treatment.
9546201 MUC-1 cytoplasmic domain peptides as inhibitors of cancer  
Peptides from the Mucin 1 (MUC1) cytoplasmic domain and methods of use therefor are described. These peptides can inhibit MUC1 oligomerization, thereby preventing tumor cell growth, inducing tumor...
9546186 Non-invasive diagnostic agents of cancer and methods of diagnosing cancer, especially leukemia and lymphoma  
The present invention is directed to novel non-invasive diagnostic tools to image cancers, especially, leukemia and non-Hodgkin's lymphomas (NHL) with minimal toxicity in vivo. The present...
9546159 N-substituted 3,4-bis (catechol) pyrrole compounds, and the preparation and use thereof in the treatment of cancer  
The present invention relates to a compound of formula (I) in which: -m is an integer from 0 to 3, preferably from 0 to 2; n is an integer from 0 to 3, preferably from 0 to 2; m+n≧1; EAG is an...
9545449 Site-specific labeling and targeted delivery of proteins for the treatment of cancer  
The present invention relates to the formation of protein conjugates from proteins chemically modified for linkage to (1) anticancer drug pharmacophores, (2) ligands to biomarkers on cancer cell...
9545417 Methods of inhibiting cancer stem cells with HMGA1 inhibitors  
The presently disclosed subject matter relates to methods of inhibiting cancer stem cells and growth of aggressive and/or poorly differentiated metastatic tumors comprising the cancer stem cells...
9540697 Prostate cancer markers  
The invention relates to the identification and selection of novel genomic regions (biomarker) and the identification and selection of novel genomic region combinations which are hypermethylated...
9540695 Compositions and methods for prognosis of ovarian cancer  
Described herein are compositions and methods for the prediction of the prognosis of ovarian cancer subjects. The present invention further provides methods for distinguishing between histological...
9540647 Methods and compositions for the treatment of cancer  
Some embodiments of the present invention relate to methods and compositions for treating cancer. More embodiments include methods and compositions for modulating the activity of the Hedgehog pathway.
9540641 Cancer treatment  
In certain embodiments, methods, compounds, and compositions for treating B-cell lymphoma or hepatocellular carcinoma by inhibiting expression of STAT3 mRNA or protein in an animal are provided...
9540619 MELK regulation for the treatment of breast cancer  
Methods for inhibiting growth or proliferation of breast cancer cells are provided. The methods include administering to a subject in need thereof in an amount that is effective to inhibit growth...
9540614 Method for generating cancer stem cells from immortalized cell lines  
A method is described for generating a novel cancer stem cell line that possesses characteristics associated with stem cells, by co-culturing a human immortalized cell line and bone marrow-derived...
9540450 Methods and antibodies for treating cancer  
The invention relates to novel methods for the treatment of tumors, comprising administration of a bispecific antibody or a combination of two or more non-cross-blocking antibodies that recognize...
9540445 Compositions and methods for treatment of cancer  
The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the...
9539340 Bladder cancer specific ligand peptides  
The present invention is directed to bladder cancer specific ligand peptides, comprising the amino acid sequence X1DGRX5GF (SEQ ID NO:1), and methods of their use, e.g., for imaging detection for...
9539327 Small molecule cancer treatments that cause necrosis in cancer cells but do not affect normal cells  
A method of treating cancer in a subject, including: providing a subject having a plurality of cancer cells; and administering to the subject, a therapeutically effective amount of a composition...
9539325 Combination therapy for treating breast cancer  
The invention provides compositions and methods for treating breast cancer. Specifically, the invention relates to administering a Transforming Growth Factor beta (TGFβ) antagonist in combination...
9539323 Methods and compositions for malic enzyme 2 (ME2) as a target for cancer therapy  
The present invention relates to methods, compositions, and diagnostic tests for treating and diagnosing cancer and other related diseases that result in dysregulation of malic enzyme 2. In...
9539290 Individualized bacterial treatment of pancreatic cancer  
An individualized bacterial treatment of cancer is provided. The treatment includes a strain of bacteria modified by in-vivo passage through tumor grafts in experimental animals, where the...
9539272 HDAC 6 inhibitor-based methods for treating cancer  
This invention provides methods for treating a subject afflicted with cancer, comprising concurrently administering (i) an HDAC 6-selective inhibitor and (ii) a suitable cytotoxic agent such as...
9539258 Quinazoline derivatives for the treatment of cancer diseases  
The present invention relates to the use of quinazolines of formula (I), wherein the groups Ra to Rd have the meanings given in the claims and specification, in cancer therapy.
9539257 Method of treating cancer  
Methods are provided of treating a human for cancer comprising administering at least one dose of lapatinib, or a pharmaceutically acceptable salt or composition thereof, to a patient, wherein...
9539254 Mutant ROS expression in human cancer  
The invention provides the identification of the presence of mutant ROS protein in human cancer. In some embodiments, the mutant ROS are FIG-ROS fusion proteins comprising part of the FIG protein...
9539237 Compositions and methods for drug-sensitization or inhibition of a cancer cell  
The disclosure provides rifamycin and rifamycin derivative compositions, including rifabutin and rifabutin derivative compositions able to cause drug-sensitization in a cancer cell or inhibition...
9539236 Pharmaceutical composition for preventing or treating cancer  
Exemplary embodiments relate to a novel anticancer composition including a compound represented by chemical formula 1 or pharmaceutically acceptable salt thereof as an active ingredient:
9539231 Method for treating triple-negative breast cancer using AMPI-109  
A targeted approach toward the treatment of TN breast cancer by using AMPI-109 is disclosed. AMPI-109 is a compound with remarkable “cancer-specific” characteristics. In particular, AMPI-109...
9539225 Anemia of cancer improving/prophylactic agent  
A method for ameliorating and/or preventing cancerous anemia includes administering to a subject in need thereof an agent containing 5-aminolevulinic acid (ALA) or a derivative thereof, or a salt...
9535069 Method of measuring cancer related substances by raman spectroscopy  
A method for measuring cancer related substances including cancer cell-derived free DNA by Raman spectroscopy, involving steps for preparing a biochip having a meso-crystal region of silver oxides...
9535068 Oral cancer point of care diagnostics  
A point of care diagnostic test, device and disposables for determining a patient risk for oral cancer in the same visit that a sample is collected.
9534999 Nanostructured biomimetic device for detecting a cancer cell or cancer cells  
The present invention provides a single cancer direct detection device comprises an electrode having a nanopore biomimetic membrane inducing a bio-communication signal by cancer cells selectively...
9534258 Devices and methods for prognosis prediction for melanoma cancer  
The invention relates to prognostic markers and prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for melanoma. Specifically,...
9534256 Methods and compositions for correlating genetic markers with risk of aggressive prostate cancer  
The present invention provides a method of identifying a subject as having an increased risk of having or developing aggressive prostate cancer, comprising detecting in the subject the presence of...
9534254 Patient stratification for cancer therapy based on genomic DNA microarray analysis  
The method of the invention comprises the stratification of a cancer patient population into various cancer therapy groups based on analysis by genomic DNA microarray of multiple gene...
9534249 Predicting cancer outcome  
This document provides methods and materials related to assessing prostate cancer in mammals. For example, this document provides nucleic acids and polypeptides that can be analyzed to determine...
9534248 Tumor-specific minicircles for cancer screening  
The present disclosure encompasses embodiments of nucleic acid minicircle vectors most advantageous for the detection of tumor cells. In particular, the minicircles of the disclosure incorporate a...
9533978 Pyrimidine derivatives and their use in the treatment of cancer and further diseases  
The invention concerns compounds of Formula (I): wherein L1, R1, R2, R3, R4 and X are as defined in the description. The present invention also relates to processes for the preparation of such...
9533054 Amphiphilic drug-drug conjugates for cancer therapy, compositions and methods of preparation and uses thereof  
The invention provides novel amphiphilic drug-drug conjugates useful as cancer therapeutics, and compositions and methods thereof.
9532984 Therapeutic combination for cancer treatment  
This invention relates to a synergistic pharmaceutical combination of glucose lowering drugs and autophagy inhibitors, kits containing such combinations, and methods of using such combinations to...
9532972 Increasing taxane sensitivity in cancer cells  
Disclosed herein are combinatorial therapies for treating or preventing reoccurrence of cancer. The therapies involve inhibition of LIMK1 in conjunction with taxane therapy. Specifically...
9532960 Pharmaceutical composition and kit for applying metformin and sodium butyrate in Kras mutation cancer treatment  
A method for using metformin and sodium butyrate in combination to treat a cancer patient with K-ras mutation is disclosed. When administering the pharmaceutical composition to a cancer patient,...
9532765 Ultrasound scanning assistance apparatus for breast cancer diagnosis and method of ultrasound scanning  
An ultrasound scanning assistance apparatus for diagnosis of a breast cancer is provided. The ultrasound scanning assistance apparatus includes a fixing container including a scan surface to scan...
9528991 Individualized cancer therapy  
In certain embodiments, the invention provides methods for treating cancer, comprising: obtaining a specimen of cancer tissue and normal tissue from a patient; extracting total protein; obtaining...