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6911471 |
S-dimethylarsino-thiosuccinic acid s-dimethylarsino-2-thiobenzoic acid s-(dimethylarsino) glutathione as treatments for cancer
Arsenic trioxide, an inorganic compound, is commercially available anti-cancer agent but it carries significant toxicity. Organic arsenicals, on the other hand, are much less toxic, to the extent...
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6908907 |
Prevention and treatment of tumor growth, metastasis, and thromboembolic complications in cancer patients
This invention provides for the prevention and treatment of tumor growth, metastasis, and cancer-mediated thrombosis through the administration, in combination, of a short or long acting GPIIb/IIIa...
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6908755 |
Human megakaryocyte-associated tyrosine kinase (MATK)-related gene variant associated with lung cancers
The invention relates to the nucleic acid of a novel human MATK-related gene variant (MATKV) and the polypeptide encoded thereby. The invention also provides a process for producing the polypeptide...
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6906091 |
Method of cancer treatment
Methods of treating and inhibiting cancer in animals by administering a therapeutically effective amount of a pharmaceutical composition having benzimidazole of the general formula:
wherein X...
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6905844 |
Human cervical cancer 2 protooncogene and protein encoded therein
A human cervical cancer 2 protooncogene having a base sequence of SEQ ID: 1 or a fragment thereof is overexpressed in various cancer tissues and can be used in diagnosing various cancers and an...
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6905833 |
Method of diagnosing breast cancer using nipple fluid
Methods and kits for detecting breast cancer or a high risk of breast cancer by measuring bFGF in nipple fluid from subjects compare the levels of bFGF in samples from test subjects with the levels...
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6903116 |
Methods of treating cancer using a heat shock factor activity inhibitor
A disease treatment is provided by controlling the expression of a protein induced by a heat shock factor. The novel compound benzo-1,3-dioxole provides an inhibitor of HSF activity or an...
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6902892 |
Method of diagnosing, monitoring, staging, imaging and treating prostate cancer
The present invention provides new methods for detecting, diagnosing, monitoring, staging, prognosticating, imaging and treating prostate cancer.
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6902890 |
Method of diagnosing monitoring, staging, imaging and treating cancer
The present invention provides new methods for detecting, diagnosing, monitoring, staging, prognosticating, imaging and treating cancer.
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6901296 |
Methods and systems for direct electrical current stimulation as a therapy for cancer and other neoplastic diseases
A small implantable stimulator(s) includes at least two electrodes for delivering electrical stimulation to surrounding tissue. The small stimulator provides means of stimulating a neoplasm with...
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6901278 |
Methods for reducing the risk of breast cancer in and improving the health of women
The subject invention provides methods for evaluating women in designing appropriate menopausal and postmenopausal therapies to match the particular needs of the individual. In one embodiment, the...
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6900240 |
Method of preparing and using compositions extracted from vegetable matter for the treatment of cancer
A composition is prepared by extracting and isolating phytochemical fractions from plant matter for treatment of cancer and especially for breast, prostate, skin, colon, urinary and bladder cancer....
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6900191 |
1α-Hydroxyvitamin D5, its synthesis and use in cancer prevention
A compound of formula I:
wherein R1 is hydrogen, R2 is —CH 3 , R3 is —CH 3 , and R4 is hydrogen, useful in cancer prevention and therapy.
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6900022 |
Prostate cancer-specific marker
This invention provides cDNA encoding a prostate-cancer specific marker, Repro-PC-1.0, Repro-PC-1.0 polypeptides and methods for use in diagnosis and therapy.
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6897018 |
DLC-1 gene deleted in cancers
A cDNA molecule corresponding to a newly discovered human gene is disclosed. The new gene, which is frequently deleted in liver cancer cells and cell lines, is called the DLC-1 gene. Because the...
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6896907 |
Use of bioactive fraction from cow urine distillate (‘go-mutra’) as a bio-enhancer of anti-infective, anti-cancer agents and nutrients
The invention relates to a novel pharmaceutical composition comprising an effective amount of bio-active fraction from cow urine distillate as a bioavailability facilitator and pharmaceutically...
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6896879 |
Method of pre-sensitizing cancer prior to treatment with radiation and/or chemotherapy and a novel cytokine mixture
This invention relates to a breakthrough method for pre-sensitizing cancer prior to a therapeutic treatment such as chemotherapy, radiation therapy or immuno-therapy and a novel cytokine mixture...
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6894146 |
Compositions and methods for the therapy and diagnosis of prostate cancer
Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides,...
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6894075 |
4′-demethyl-4′-O-substituted-1-deoxypodophyllotoxin derivative and geometric isomer thereof, process for the preparation thereof and anti-cancer composition comprising the same
The present invention provides a novel 4′-demethyl-4′-O-substituted-1-deoxypodophyllotoxin derivative, a geometric isomer thereof, a process for the preparation thereof, and an anticancer...
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6894073 |
Use of diterpene compound as a therapeutic agent of inflammation, immune disease or cancer
The disclosure concerns novel use of diterpene compound as a therapeutic agent of inlfammation, immune disease or cancer. More particularly, the present invention relates to novel use of diterpene...
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6894071 |
Medical compositions for intravesical treatment of bladder cancer
Anti-cancer coating compositions comprising 3-hydroxymethyl-5-aziridinyl-1-1-methyl-2-[1H-indole-4,7-dio
ne]propenol (E09) are disclosed. More specifically, the coating compositions comprise EO9...
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6894026 |
Long-acting oxytocin analogues for the treatment and prevention of breast cancer and psychiatric disorders
Methods and compositions are provided for prophylaxis and treatment of breast cancer involving administration of a therapeutically effective amount of carbetocin and/or other long-acting oxytocin...
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6893818 |
Gene upregulated in cancers of the prostate
The present invention relates to a novel protein designated 20P2H8 which shares homology with several heterogenous nuclear ribonucleoproteins (hnRNPs). A full length approximately 3600 bp 20P2H8...
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6892140 |
Immunogenic cancer peptides and uses thereof
This invention relates to novel general methods and compositions that provide cancer-specific or highly cancer-associated antigens useful for diagnosis and treatment of cancer.
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6890946 |
Use of parthenolide to inhibit cancer
The invention provides a method comprising the use of parthenolide, including its analogs, to treat cancer or conditions characterized by abnormal angiogenesis.
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6890917 |
Geldanamycin derivative and method of treating cancer using same
A geldanamycin derivative exhibiting significant preliminary in vivo activity, particularly significant oral in vivo activity, and a method of treating or preventing cancer in a host comprising...
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6890514 |
Methods for determining risk of developing cervical cancer
The present invention relates generally to a method of identifying a subject having an increased risk of developing cervical cancer based on levels of IGF-II in serum and levels of EGF-R and...
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6888014 |
Dammarane sapogenins, their use as anti-cancer agents, and a process for producing same
This invention relates to a group of novel sapogenins, their use in anti-cancer applications, and to a process for their production. More particularly, this invention pertains to a novel group of...
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6887660 |
Compounds for immunodiagnosis of prostate cancer and methods for their use
Compounds and methods for diagnosing prostate cancer are provided. The inventive compounds include polypeptides containing at least a portion of a prostate tumor protein. The inventive polypeptides...
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6887210 |
Devices and methods for obtaining mammary fluid samples for evaluating breast diseases, including cancer
Biological samples of mammary fluid or components thereof are obtained using a breast pump device coupled with a solid phase sample collection medium, alternatively facilitated by administering...
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6884605 |
Compositions, methods and products comprising human papillomavirus for detecting and treating a cancer
Methods for screening a patient for a cancer wherein the methods comprise detecting an HPV in a biopsy from a patient are disclosed. Also disclosed are compositions and products for screening and...
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6884581 |
Method for identifying a test compound that modulates expression of a Fra-1 gene in a brain cancer cell
Fra-1 serves as a target for diagnosing and treating glioblastoma multiforme and related brain cancers. Cancer in a brain tissue sample is detected by analyzing expression of Fra-1 in the sample....
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6884439 |
Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol
The invention relates to the use of arsenic compounds to treat a variety of leukemia, lymphoma and solid tumors. Further, the arsenic compounds may be used in combination with other therapeutic...
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6884418 |
Use of ligand-mimicking agents and anti-neoplastic drugs in cancer therapy
This invention is directed toward novel synergistic combinations of ligand-mimicking agents specific to the c-erbB-2 protein and anti-neoplastic drugs or agents, which can be used to treat a...
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6881574 |
Noninvasive detection of colorectal cancer and other gastrointestinal pathology
A method for isolating viable, biologically substantially pure exfoliated fecal colonocytes at normal ambient temperature is described. Immunocoprocytes and inflammatory cells indicative of certain...
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6881420 |
Compositions and dosage forms for gastric delivery of irinotecan and methods of treatment that use it to inhibit cancer cell proliferation
The present invention provides oral dosage forms and compositions for administering antineoplastic agents, such as irinotecan, etoposide, paclitaxel, doxorubicin and vincristine, whose oral...
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6878526 |
Treating cancer
Provided is a method for the diagnosis of a cancerous or pre-cancerous state in a subject, comprising testing a sample comprising cells or an extract therefrom for the co-elevation of CDK1 and...
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6875745 |
Method and composition for the treatment of cancer
We have discovered that the administration of a G1 and/or S phase drug such as β-lapachone in combination with a G2/M drug such as a taxane derivative such as paclitaxel resulted in a greater than...
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6875609 |
Methods for the early diagnosis of ovarian cancer
The disclosed nucleic acid primer sets, used in combination with quantitative amplification (PCR) of tissue cDNA, can indicate the presence of specific proteases in a tissue sample. Specifically,...
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6872533 |
STK15 (STK6) gene polymorphism and methods of determining cancer risk
The present invention provides methods for determining cancer susceptibility in a human subject by identifying in a nucleic acid sample from the subject, a nucleotide occurrence of a single...
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6872517 |
Early diagnosis of cancerous and precancerous conditions by leakage of signature peptides and carbohydrates into the bloodstream
The present invention involves the early diagnosis of cancerous or precancerous conditions in the gastrointestinal tract by detection of a backleak of signature proteins or carbohydrates in a...
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6870027 |
Methods for the early diagnosis of ovarian cancer
The disclosed nucleic acid primer sets, used in combination with quantitative amplification (PCR) of tissue cDNA, can indicate the presence of specific proteases in a tissue sample. Specifically,...
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6869795 |
Antisense compositions and cancer-treatment methods
A composition antisense oligomer directed to an mRNA preferentially expressed together with methods for treating stem cells with such a composition to increase the number of lineage committed...
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6869760 |
Use of prostate tumor inducing gene for detection of cancer cells
This invention provides a method for detecting cancer cells in a sample comprising detection of the expression of a Prostate Tumor Inducing Gene in the sample, wherein a positive detection of the...
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6869592 |
Method and antibody for imaging lung cancer
The present invention provides new methods for detecting, diagnosing, monitoring, staging, prognosticating, imaging and treating lung cancer.
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6867238 |
Compositions for the treatment and prevention of cancer
Compositions are provided for the topical treatment of cancer consisting of lotions, creams, sprays, suppositories or slow-release transdermal patches containing lipid-soluble, skin-penetrating...
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6867235 |
Helianthrone derivatives as anti-cancer agents
Hypericin, helianthrone and derivatives thereof of general formula (I)
wherein the dotted line between positions 11 and 12 represent an optional C11-C12 bond; R is independently selected from...
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6867034 |
Methods of screening novel agents for use in cancer therapy and prevention
The present invention provides for methods of screening agents for cancer therapeutic and prophylactic activity. In particular embodiments, cells of the cellular slime mold Dictyostelium...
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6864275 |
Compounds and methods for use thereof in the treatment of cancer
Benzimidazole derivatives and salts and prodrugs thereof are disclosed, together with methods for the treatment of cancers or viral infections in warm blooded animals by administration of these...
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6864272 |
Method and composition for treating cancer using cellular organelle crystallizing agents
This invention provides a method for treating cancer in mammals through cellular-organelle-crystallization-induced-death (herein defined as “Cocid”), a method for treating cancer using cellular...
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