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10214743 Colorectal cancer drug, and method for predicting prognosis of colorectal cancer patient  
The purpose of the present invention is to provide a colorectal cancer drug that uses microRNA exhibiting outstanding effectiveness in colorectal cancer patients, particularly colorectal cancer...
10214577 Peptides and combination of peptides for use in immunotherapy against esophageal cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10214558 Natural and synthetic compounds for treating cancer and other diseases  
This invention provides a method of synthesizing new active compounds for pharmaceutical uses including cancer treatment, wherein the cancers comprise breast, leukocytic, liver, ovarian, bladder,...
10214529 Small molecules for the treatment of primary cancer and cancer metastasis  
Certain embodiments and compounds are of the class of non-hydrolysable ATP analogs and adenosine receptor antagonists, useful for inhibiting the migration and growth of cancer cells.
10213515 Glycopeptide for contrast agent targeting cancer cells and contrast agent kit containing the same  
The present disclosure relates to a glycopeptide targeting cancer cells and a contrast agent kit containing the same. The glycopeptide is one wherein an azide reporting monosaccharide is bound to...
10213499 Peptides and combination of peptides for use in immunotherapy against breast cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10213454 Methods of inhibiting cancer stem cells with HMGA1 inhibitors  
The presently disclosed subject matter relates to methods of inhibiting cancer stem cells and growth of aggressive and/or poorly differentiated metastatic tumors comprising the cancer stem cells...
10213445 Compositions and methods of diazeniumdiolate-based prodrugs for treating cancer  
The present disclosure provides methods utilizing the diazeniumdiolate-based prodrugs for the treatment of cancer via various mechanisms and procedures. The disclosure also provides kits...
10213436 Methods of treating cancer using aurora kinase inhibitors  
Disclosed are methods for the treatment of various cell proliferative disorders. Disclosed in particular are methods for treatment of various cell proliferative disorders by administering a...
10213414 Glucocorticoid receptor modulators to treat pancreatic cancer  
Methods and compositions for treating a subject hosting a non-ACTH-secreting pancreatic tumor are disclosed. The methods include administering to the subject a chemotherapeutic agent and a...
10213401 Immunomodulatory and differentiating function selective retinoid and rexinoid compounds in combination with immune modulators for cancer immunotherapy  
Disclosed herein are methods for treating cancer comprising administering CAR-modified immune cells and at least one Retinoic Acid Receptor and/or Retinoid X Receptor active agent.
10213385 Combinational liposome compositions for cancer therapy  
The present invention provides methods for delivery of therapeutic agents to a subject using multi-component liposomal systems. The methods include administration of a therapeutic liposome...
10213128 UWB microwave imaging system with a novel calibration approach for breast cancer detection  
An apparatus and method for imaging a tissue. The method includes transmitting a first microwave frequency signal to and receiving a first total signal from the tissue at a first position. A...
10208354 NRG1 fusion genes in cancer  
The present invention relates to novel fusion genes comprising NRG1 and a further fusion partner, like CD74. The present invention provides for the use of these fusion genes in diagnosis as well...
10208353 Biomarkers useful for detection of types, grades and stages of human breast cancer  
The present invention relates to biomarkers useful for detection of types, grades and stages of human breast cancer. The present invention particularly relates to the development of these...
10208130 Quantifying Her2 protein for optimal cancer therapy  
Improved methods of treatment are provided for patients suffering from cancer. The methods identify whether a tumor will be responsive to treatment with a therapeutic regime that includes...
10208086 Cyclin A1-targeted T-cell immunotherapy for cancer  
Compositions and methods are provided for eliciting antigen-specific T-cell responses against human cyclin A1 (CCNA1), which is herein identified as a leukemia-associated antigen based on its...
10208028 Methods of treating cancer  
One embodiment is a method of treating cancer. The method includes administering a therapeutically effective amount of a compound to a patient. The compound is represented by Formula I:
10207988 Methods and compositions for treatment of cancer and autoimmune disease  
The technology described herein relates to methods of inducing cell death. The technology described herein further relates to treating conditions including cancers and autoimmune diseases...
10206990 Cytotoxic T lymphocyte inducing immunogens for prevention treatment and diagnosis of cancer  
The present invention relates to compositions and methods for the prevention, treatment, and diagnosis of cancer, especially carcinomas, such as pancreatic carcinoma. The invention discloses...
10206988 Xenoantigen-displaying anti-cancer vaccines and method of making  
Compositions, methods of making, and methods of using, xenoantigen-displaying anti-cancer vaccines are described.
10206987 Protein nanoparticle linked with cancer specific epitope and composition for cancer immunotherapy comprising the same  
The present invention relates to a protein nanoparticle having a surface on which a cancer-specific epitope is fused and expressed, a method for producing the same, and a composition for cancer...
10206985 WT1 peptide cancer vaccine composition for mucosal administration  
The present invention provides a cancer vaccine composition for mucosal administration for inducing cellular immunity, comprising (i) a WT1 peptide and/or a modified WT1 peptide; and (ii) a...
10206920 Pharmaceutical composition for treating cancer and a method of using the same  
The invention provides a pharmaceutical composition and a method for treating cancer, and the composition comprises a proteasome inhibitor and a nuclear export inhibitor. The composition has...
10206916 Cabozantinib salts and their use as anti-cancer agents  
The present invention relates to crystalline forms of cabozantinib succinate (Form A) and cabozantinib acetate (Form A-1) and to pharmaceutical compositions comprising said crystalline forms and...
10206910 Apilimod for use in the treatment of renal cancer  
The present disclosure relates to methods for treating renal cancer with apilimod and related compositions and methods.
10206875 Nanoemulsion compositions of taxoid drugs, and methods for the use thereof to target cancer cells and cancer stem cells  
A composition of an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate encapsulated in an oil-in-water nanoemulsion (NE) drug delivery system. A method of treating cancer by administering...
10203343 Diagnosis of cancer by detecting auto-antibodies against epidermal growth factor (EGF)  
The present invention relates to a method for diagnosis of a cancer, comprising the steps of (i) determining the level of antibodies against epidermal growth factor (EGF) in a sample from a...
10203329 Biofilm formation to define risk for colon cancer  
Methods of identifying subjects at increased risk of cancer, based upon detection of biofilms and/or biofilm-associated microbes within a subject, are disclosed. Therapies designed to prevent...
10202653 Compositions and methods for detecting markers associated with bladder cancer  
Compositions and methods for detecting bladder cancer are provided. In some embodiments, methods of monitoring recurrence of bladder cancer are provided. In some embodiments, the methods comprise...
10202463 Cell-based anti-cancer compositions with reduced toxicity and methods of making and using the same  
Isolated pluralities of T cells which recognize at least one epitope of an intestinal cancer antigen or CNS cancer antigen and pharmaceutical compositions comprising the same are disclosed....
10202458 IGF-1R antibody and its use as addressing vehicle for the treatment of cancer  
The present invention relates to an antibody, in particular a monoclonal antibody, capable of binding to IGF-1R, as well as the amino and nucleic acid sequences coding for said antibody. From one...
10202457 Anti-DEspR monoclonal antibody targeted therapy and imaging for cancer and stroke  
Provided herein are novel compositions comprising anti-DEspR antibodies and fragments thereof derived from 6G8G7 and 7C5B2 anti-DEspR variant antibodies, including fully human, composite...
10202437 Peptides and combination of peptides for use in immunotherapy against esophageal cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10202398 Benzimidazole derivatives as ERBB tyrosine kinase inhibitors for the treatment of cancer  
Provided herein are benzimidazole derivatives, for example, of Formula (I), and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or...
10202397 Anti-cancer compounds targeting Ral GTPases and methods of using the same  
Methods of inhibiting the growth or metastasis of a cancer in a subject by inhibiting a Ral GTPase in the subject, and small molecule inhibitors of Ral GTPases useful in the methods of the...
10202357 Class of quinolone heterocyclic aromatic molecules for cancer treatment  
The invention is directed to new class of quinolone heterocyclic aromatic molecules (Renotinibs) and their use in the treatment of cancer, in particular, cancer that harbor abnormal human...
10201651 Systems and methods for destroying cancer cells in blood  
An apparatus for destroying cancer cells in blood includes a vessel for accepting a flow of blood of a patient through the vessel, and a sound energy source coupled with the vessel for generating...
10201611 Pharmaceutical composition comprising estetrol derivatives for use in cancer therapy  
The present invention relates to a method of treating or preventing estrogen-sensitive tumours in a mammal, said method comprising the administration of a therapeutically effective amount of an...
10201530 Treatment of BRCA1-defective cancer or resistant cancers  
Provided herein are methods of treating cancer in a subject by administering COH29 ((N-(4-(3,4-dihydroxyphenyl)-5-phenylthiazol-2-yl)-3,4-dihyd roxybenzamide)). The methods of treating include...
10201521 Use of substituted hexitols including dianhydrogalactitol and analogs to treat neoplastic disease and cancer stem and cancer stem cells including glioblastoma multiforme and medulloblastoma  
The use of dianhydrogalactitol provides a novel therapeutic modality for the treatment of glioblastoma multiforme and medulloblastoma. Dianhydrogalactitol acts as an alkylating agent on DNA that...
10197563 3-D in vitro model for breast cancer dormancy  
Disclosed is a three-dimensional (3-D) in vitro model for studying and subsequently treating cancer dormancy. The model is specifically useful in studying breast cancer and may be used for drug...
10196698 DNA methylation markers for metastatic prostate cancer  
The present invention relates to the field of cancer. More specifically, the present invention provides methods and compositions useful for assessing prostate cancer. In a specific embodiment,...
10196697 Prostate cancer classification  
A method is provided for characterizing and/or prognosing prostate cancer in a subject comprising determining the expression level of at least one of CREM, ERRFI1, SRSF5, PDK4, HJURP, PDRG1,...
10196696 RNA-biomarkers for diagnosis of prostate cancer  
The invention relates to the identification and selection of differentially expressed transcripts (biomarker) in tumour cells. Specific determination of the level of these biomarkers can be used...
10196695 RNA-biomarkers for diagnosis of prostate cancer  
The invention relates to the identification and selection of differentially expressed transcripts (biomarker) in tumour cells. Specific determination of the level of these biomarkers can be used...
10196694 Method for analyzing PSA, and a method for distinguishing prostate cancer from prostatic hypertrophy using that method for analyzing PSA  
A method for distinguishing prostate cancer from prostatic hypertrophy using the method for analyzing PSA and an analysis kit of PSA are provided. An object of the present invention can be solved...
10196693 Method for predicting response to breast cancer therapeutic agents and method of treatment of breast cancer  
Methods for treating triple negative breast cancer with an androgen receptor inhibitor are provided, as well as methods for screening for the likelihood of the effectiveness of such treatment.
10196691 Colon cancer gene expression signatures and methods of use  
A gene expression signature of colon cancer, microarrays including them and methods of using the colon gene expression signature are provided. The gene expression signature is especially useful...
10196687 Molecular diagnosis and typing of lung cancer variants  
Compositions and methods useful in determining the major morphological types of lung cancer are provided. The methods include detecting expression of at least one gene or biomarker in a sample at...