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7008778 |
Breast cancer specific gene 1
The present invention relates to a novel BCSG1 protein. In particular, isolated nucleic acid molecules are provided encoding the human BCSG1 protein. BCSG1 polypeptides are also provided as are...
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7008772 |
Compounds for immunodiagnosis of prostate cancer and methods for their use
Compounds and methods for diagnosing prostate cancer are provided. The inventive compounds include polypeptides containing at least a portion of a prostate tumor protein. The inventive polypeptides...
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7008649 |
Cancer treatment composition and method using natural plant essential oils with signal transduction modulators
Pharmaceutical compositions containing plant essential oil compounds, natural or synthetic, or mixtures or derivatives thereof, with one or more signal transduction modulators, for the prevention...
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7005424 |
Nucleic acid encoding an E1A gene product sensitizes HER-2/neu overexpressing cancer cells to chemotherapy
The present invention relates to methods for the inhibition, of the gene product of the neu oncogene, p185neu tyrosine kinase. Over-expression of the neu oncogene leads to chemoresistance. The...
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7005146 |
Complex prescription of chinese medicine for the treatment of extensive cancer
A complex prescription of Chinese medicine for the treatment of extensive cancer, or cancer of relation type of the lymph node. The ingredients of this complex prescription are Pilose asiabell...
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7005139 |
Compositions and methods for the targeted delivery of agents to treat liver cancer
The invention provides compositions containing an effective amount of a therapeutic agent encapsulated in a liposome coupled to a desialyated glycoprotein, e.g., desialyated glycoprotein-α1. This...
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7001991 |
Targeted delivery of bioaffecting compounds for the treatment of cancer
A homogeneous conjugate for targeting and treating diseased cells wherein the conjugate comprises an anti-cancer drug and a targeting protein, wherein said anti-cancer drug is selected from the...
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7001925 |
Compounds and method for enhancing the efficacy of anti-cancer drugs
Polyamine compounds, method of synthesis and method of use for anti-cancer purposes, and for enhancing the activity of existing anti-cancer drugs are provided. This disclosure has identified...
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7001888 |
Compositions and methods for treating cancer
Methods and compositions are provided for the treatment of cancer that take advantage of the increased uptake of glucose-anti-neoplastic agent conjugates in cancer cells relative to normal cells.
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7001616 |
Microspheres for use in the treatment of cancer
The subject invention pertains to novel materials and methods for use in treating patients afflicted with oncological disorders, such as tumors. One aspect of the invention concerns methods for...
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6998384 |
Surfactant prevention of lung complications from cancer chemotherapy
A means and method for treating pulmonary fibrosis in animals is described. The compositions include surfactant lipids in a pharmaceutically acceptable carrier. Surfactant lipids have been found to...
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6998234 |
Methods for cancer prognosis and diagnosis relating to tumor vascular endothelial cells
The invention provides methods for prognosis, diagnosis, staging and disease progression in human cancer patients related to expression levels of a plurality of genes that are differentially...
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6998232 |
Methods of diagnosing bladder cancer
There is provided a method of diagnosing the presence of bladder cancer in a patient by analyzing a tissue sample from the patient for the presence of a least one expressed gene wherein the...
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6998141 |
Medication combination for hepatoma and pancreatic cancer and preparation protocol
This invention discloses a medication combination, consisting of Baizhu, Danggui, Hanxincao, Huotanmucao, Ainaxiang, Shuodiao, Malan, Ludou, Canger, Daqinggen, Banbianlian, Xingren, Nuzhenzi,...
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6998125 |
Synergistic composition and methods for treating neoplastic or cancerous growths and for restoring or boosting hematopoiesis
The present invention provides a synergistic composition and methods for treating neoplastic or cancerous growths as well as for treating such patients in order to restore or boost hematopoiesis....
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6998117 |
Cancer treatment with retroviral vectors comprising wild-type p53
Disclosed are methods and compositions for the selective manipulation of gene expression through the preparation of retroviral expression vectors for expressing antisense sequences, such as K-ras...
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6995188 |
S-dimethylarsino-thiosuccinic acid s-dimethylarsino-2-thiobenzoic acid s-(dimethylarsino) glutathione as treatments for cancer
Arsenic trioxide, an inorganic compound, is commercially available anti-cancer agent but it carries significant toxicity. Organic arsenicals, on the other hand, are much less toxic, to the extent...
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6992207 |
Melphalan derivatives and their use as cancer chemotherapeutic drugs
The invention refers to new alkylating di- and tripeptides based on a melphalan unit, and one or two additional amino acids or amino acid derivatives, which can be used in the treatment of...
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6992176 |
Antibody having a T-cell receptor-like specificity, yet higher affinity, and the use of same in the detection and treatment of cancer, viral infection and autoimmune disease
An isolated molecule which comprises an antibody specifically bindable with a binding affinity below 20 nanomolar, preferably below 10 nanomolar, to a human major histocompatibility complex (MHC)...
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6989383 |
Method of treating cancer
The present invention relates to methods of treating cancer using a combination of a compound which is an antineoplastic agent and a compound which is a inhibitor of prenyl-protein transferase,...
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6989371 |
Bombesin analogs for treatment of cancer
The present invention encompasses novel peptides that are antagonists to bombesin and bombesin like peptides and are useful in the treatment of cancer. The invention particularly relates to the...
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6989253 |
Biological compositions and methods for treatment of testicular cancer
The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with testicular cancer. The...
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6989140 |
Methods for cancer imaging
Methods are provided for cancer and pre-cancer detection by increased uptake of fluorophore glucose or deoxyglucose conjugates in cancerous and pre-cancerous cells relative to normal cells.
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6987012 |
Biological compositions and methods for treatment of colorectal cancer
The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with colorectal cancer. The...
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6986891 |
Myeloma cell and ovarian cancer cell surface glycoproteins, antibodies thereto, and uses thereof
The present invention is directed to cell surface antigens found on myeloma cells and on ovarian cancer cells, and monoclonal antibodies, and antibody binding fragments thereof, capable of being...
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6984654 |
Cancer treatments and pharmaceutical compositions therefor
A pharmaceutical composition that inhibits the growth of tumors and cancers in mammals and can be used to treat viral infections that comprises a fungicide is disclosed. The particular fungicide...
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6984508 |
Biological compositions and methods for treatment of cervical cancer
The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with cervical cancer. The...
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6984507 |
Biological compositions and methods for treatment of lung cancer
The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with lung cancer. The...
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6984498 |
Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques
A cancer screening method is provided, wherein the method is characterized by administering a compound to a patient, the compound being a complex of a fluorescent marker and a radioactive marker,...
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6984384 |
Stress protein compositions and methods for prevention and treatment of cancer and infectious disease
Pharmaceutical compositions comprising a stress protein complex and related molecules encoding or cells presenting such a complex are provided. The stress protein complex comprises an hsp110 or...
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6982351 |
Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
Conformationally restricted polyamine compounds useful in treatment of cancer and other diseases marked by abnormal cell proliferation are disclosed. Improved methods of synthesizing such compounds...
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6982316 |
Isolated nucleic acid molecules associated with colon cancer and methods for diagnosing and treating colon cancer
Various molecules associated with disorders such as cancer are disclosed. The invention also discloses diagnostic aid therapeutic methods based upon these molecules, as well as compositions for...
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6982168 |
Immortal human prostate epithelial cell lines and clones and their applications in the research and therapy of prostate cancer
The present invention relates to immortalized, malignant, human, adult prostate epithelial cell lines or cell lines derived therefrom useful in the diagnosis and treatment of prostate cancer. More...
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6982148 |
Progressive elevated gene-3 (PEG-3) induces aggressive cancer phenotype and regulates angiogenesis
The present invention provides a method for identifying a gene which is expressed at a modulated level in an aggressive cancer by: (a) measuring baseline expression levels of genes in cancer cells;...
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6982096 |
Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol
The invention relates to the use of arsenic compounds to treat a variety of leukemia, lymphoma and solid tumors. Further, the arsenic compounds may be used in combination with other therapeutic...
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6982091 |
Vaginal delivery of chemotherapeutic agents and inhibitors of membrane efflux systems for cancer therapy
Devices, methods, and compositions for cancer therapy by administration of chemotherapeutic agents and/or inhibitors of membrane efflux systems to the vagina for topical and systemic tumor targets.
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6979681 |
Half-sandwich ruthenium (II) compounds comprising nitrogen containing ligands for treatment of cancer
Ruthenium (II) compounds of the formula:
wherein: R 1 is —CO 2 CH 3 ; R 2 , R 3 , R 4 , R 5 and R 6 independently represent H, alkyl, cylcoalkyl, —CO 2 R′, aryl or alkylaryl, which...
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6979675 |
Treatment of cancer with 2-deoxyglucose
The compound 2-deoxyglucose can be used to treat cancer and to improve patient outcome when administered at a therapeutically effective dose, and, optionally, co-administered with other anti-cancer...
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6978788 |
Minimally invasive treatment for breast cancer
The present invention provides a minimally invasive, comprehensive same-day diagnosis and treatment method to remove tumor and ablate margins in breast cancer patients, comprising disease diagnosis...
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6977296 |
HUMAN CERVICAL CANCER SUPPRESSOR PROTEIN, POLYNUCLEOTIDE ENCODING THE PROTEIN, CELL TRANSFORMED WITH THE POLYNUCLEOTIDE AND METHOD FOR SUPPRESSING PROLIFERATION OF CANCER CELL USING THE EXPRESSION VECTOR
The present invention provides a human tumor suppressor protein having the amino acid sequence of SEQ ID NO: 2; a polynucleotide encoding the tumor suppressor protein; an expression vector...
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6977250 |
Prevention of ovarian cancer by administration of progestin products
The present invention relates to methods for preventing the development of epithelial ovarian cancer by administering progestin products, either alone or in combination with other agents such as...
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6975702 |
Method for inactivating cancer cells in a human body and apparatus
An X-ray apparatus for inactivating cancer cells in a human body is disclosed. The X-ray apparatus has four X-ray guns. Each of the four X-ray guns generating a separate frequency of an X-ray...
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6974672 |
Gene amplification in cancer
There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing the CTSZ and CD24 genes, which are...
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6974667 |
Gene expression profiles in liver cancer
The present invention identifies the global changes in gene expression associated with liver cancer by examining gene expression in tissue from normal liver, metastatic malignant liver and...
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6974664 |
Screening method for cancer therapeutics and stable antitumor drug
Screening methods and methods of treatment taking advantage of the mode of action of apoptolidin and its analogs are described.
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6972181 |
Differential diagnosis of cancer and other conditions based on expression of p63
This invention relates to methods of distinguishing among various types of differentiated and undifferentiated epithelial carcinomas, and non-epithelial carcinomas, by detecting the presence of p63...
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6972170 |
Markers for prostate cancer
This invention provides a method for determining the aggressiveness of a prostate carcinoma comprising: (a) obtaining a sample of the prostate carcinoma; and (b) detecting the presence of p27...
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6972128 |
Use of human prostrate cell lines in prostate cancer treatment
The invention here relates to a product comprised of a cell line or lines intended for use as an allogeneic immunotherapy agent for the treatment of cancer in mammals and humans. All of the studies...
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6969518 |
Compositions and methods for the therapy and diagnosis of breast cancer
Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic...
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6964846 |
Methods for detecting nucleic acids indicative of cancer
The invention provides methods for screening tissue or body fluid samples for nucleic acid indicia of cancer or precancer. Method are provided for screening a patient for cancer or precancer by...
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