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9926607 Breast cancer biomarkers and methods of using same  
The present invention provides breast cancer markers based on RECQL mutations, and related methods, uses, agents, and kits. The invention includes methods for determining the susceptibility of a...
9926605 Functional genomics screening platform for head and neck cancer  
The present invention relates to HPV-positive as well as HPV-negative screening platforms that are highly serum-dependent, for use as HNSCC models. These HNSCC models die reproducibly in...
9926602 Recurrent gene fusions in prostate cancer  
The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to...
9926601 Alternatively spliced mRNA isoforms as prognostic indicators for metastatic cancer  
The present invention provides a method for identifying a tumor as likely to metastasize, or likely to have metastasized, comprising obtaining a sample of the tumor and quantitating alternatively...
9926374 Human immune therapies using a CD27 agonist in combination with another immune agonist to treat cancer  
Methods of inducing T cell proliferation and expansion in vivo for treating conditions wherein antigen-specific T cell immune response are therapeutically desirable such as cancer, infection,...
9926369 Methods for treating hepatocellular cancer by administering an anti-Ang-2 antibody  
The present invention provides antibodies that bind to angiopoietin-2 (Ang-2) and methods of using same. According to certain embodiments of the invention, the antibodies are fully human...
9926334 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Compositions to detect remnant cancer cells
 
Disclosed are compounds, compositions and methods for detecting remnant cancer cells in a tissue sample.
9925269 Phospholipid ether analogs as cancer-targeting drug vehicles  
The present invention is directed to therapeutic compounds capable of targeting cancer cells and cancer stem cells. The present invention is further directed to compositions comprising these...
9925240 Methods of treating and preventing cancer drug resistance  
Provided herein are combination therapies for the treatment of pathological conditions, such as cancer, using an antagonist of FGFR signaling.
9925192 Method for treating cancer  
A method for the treatment of cancer by administering a therapeutically effective amount of a cyclin-dependent kinase (CDK) inhibitor with a therapeutically effective amount of a B cell chronic...
9925142 Use of liposomes in a carrier comprising a continuous hydrophobic phase as a vehicle for cancer treatment  
The invention compositions comprising a continuous hydrophobic phase and liposomes as a vehicle for delivery of an antigen capable of inducing a cytotoxic T lymphocyte (CTL) response and methods...
9921224 Use of CD36 to identify cancer subjects for treatment  
Provided herein are methods for identifying a subject with cancer for treatment with a Psap peptides. The subject is identified based on a level of CD36. Also provided herein are compositions and...
9920377 FALZ for use as a target for therapies to treat cancer  
The disclosure provides methods for predicting and/or determining whether a subject has cancer based on the level of expression of BPTF. The disclosure also provides methods for determining...
9920376 Method for determining lymph node metastasis in cancer or risk thereof and rapid determination kit for the same  
The objective of the present invention is to provide a method and a means of rapidly and reliably detecting lymph node metastasis in cancer or the risk of lymph node metastasis. Specifically, the...
9920297 Salmonella-based vectors for cancer immunotherapy targeting wilms' tumor gene WT1  
The present invention relates to an attenuated mutant strain of Salmonella comprising a recombinant DNA molecule encoding Wilms' tumor Protein 1. In particular, the present invention relates to...
9920130 Recombinant human IgM-antibody effective against cancer cells  
A recombinant human monoclonal pentameric IgM antibody comprising the capability of oligospecific binding to purified ganglioside epitopes GD3, GM3, GD2 and GM1 and the capability of specific...
9920129 Diagnosis and treatment of cancer using anti-ITM2A antibody  
Disclosed is a monoclonal antibody binding to an ITM2A protein. This antibody is useful in the diagnosis, prevention, and treatment of cancer such as Ewing's sarcoma, T cell leukemia, T cell...
9920099 Anti-cancer compositions containing Wnt decoy receptor  
The present invention relates to a composition for preventing or treating cancer comprising Wnt decoy receptor. The composition of the present invention or the expression product thereof inhibits...
9920095 Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders  
The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorder, inflammation or cancer (e.g., a...
9919062 Oncolytic vaccinia virus cancer therapy  
Embodiments of the invention are directed methods that include a thymidine kinase deficient vaccinia virus. The methods include administering the vaccinia virus at increased viral concentrations....
9919058 Polyketal particles including a CpG oligodeoxynucleotide for the treatment of lung cancer  
Methods are disclosed herein for treating a subject with a lung cancer. The lung cancer can be small cell carcinoma of the lung or non-small cell carcinoma of the lung. The methods include locally...
9919023 Anti-androgen peptides and uses thereof in cancer therapy  
The present invention relates to isolated or purified or partially purified peptide derived molecules having the following general formula (S1): X-[(Pro)n-His-Pro-His-Ala-Arg-Ile-Lys]m-Y. The...
9919016 Product and method of deploying kale derivatives for anti-cancer effects  
The present disclosure describes chemopreventative and/or chemotherapeutic compositions for inducing apoptosis in cancer cells which include kale and methods of inducing apoptosis in cancer cells...
9919000 Altering cancer cellular functions through proton mopping  
Proton mopping is a new anti-cancer therapeutic approach that disrupts cancer's immunologic balance. It results in the alteration of the pHi/pHe ratio (intracellular-extracellular) of the cancer...
9918983 Suicidal LSD1 inhibitors targeting SOX2-expressing cancer cells  
Disclosed are inhibitors of lysine-specific demethylase I (LSD1); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating cancers...
9918968 Rapamycin analogs targeting proteasome function in the treatment of cancer  
The invention provides for treatment of cancers using a rapamycin analog, optionally including bortezomib. In particular, the invention addresses the treatment of bortezomib-resistant cancers...
9918966 Anti-cancer compositions and methods  
Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present invention. Methods of treating a subject...
9918950 Targeted treatment of anerobic cancer  
The present invention relates to a pharmaceutical cocktail and methods of treatment involving said cocktail, in particular, a combination of effective amounts of a carbonic anhydrase inhibitor, in...
9915661 Composition, kit, and method for diagnosing and treating ovarian cancer  
Provided are a composition, a kit, and a method of predicting prognosis of ovarian cancer or a risk of recurrence of ovarian cancer. Provided are a composition for treating ovarian cancer or...
9915660 Methods for determining prognosis of colorectal cancer  
Provided herein are methods for determining the risk that a subject diagnosed with colorectal cancer will develop a recurrence of colorectal cancer and methods of predicting clinical outcome for a...
9914977 Individualized cancer therapy  
In certain preferred embodiments, the invention provides methods for treating cancer, which comprise (a) obtaining a specimen of cancer tissue from a patient; (b) obtaining a specimen of normal...
9914976 Methods and compositions for prostate cancer metastasis  
Provided are methods and compositions for determining an increased likelihood of prostate cancer cells in a subject to metastasize.
9914974 Molecular biomarker set for early detection of ovarian cancer  
Embodiments of the present invention concern methods and compositions related to detection of ovarian cancer, including detection of the stage of ovarian cancer, in some cases. In particular, the...
9914972 Methods for lung cancer classification  
The present invention provides specific nucleic acid sequences for use in the identification, classification and diagnosis of various sub-types of lung cancers. The present invention permits one...
9914775 Methods for treating inflammatory disorders or cancer metastasis by administering antibodies to connexin 43 (Cx43) hemichannels  
Methods for identifying compounds that positively regulate connexin 43 hemichannels.
9914768 Anti-S100A7 antibodies for the treatment and diagnosis of cancer  
The present invention relates to the use of antibodies against S100A7 protein for the prevention and/or treatment of cancer or a disease associated to an undesired angiogenesis or a disease...
9914752 Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders  
The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a...
9913846 Combination of a PI3 kinase inhibitor with pacitaxel for use in the treatment or prevention of a cancer of the head and neck  
A pharmaceutical combination comprising (a) a phosphatidylinositol-3-kinase (PI3K) inhibitor compound of formula (I), as defined herein, or a pharmaceutically acceptable salt thereof and (b)...
9913838 Methods of treating cancer using compositions comprising perillyl alcohol derivative  
A method for treating brain metastases of a cancer in a mammal includes administering to the mammal a therapeutically effective amount of a perillyl alcohol carbamate, such as TMZ-POH. The brain...
9913816 Method for applying metformin and sodium butyrate in K-ras mutation cancer treatment  
A method for using metformin and sodium butyrate in combination to treat a cancer patient with K-ras mutation is disclosed. When administering the pharmaceutical composition to a cancer patient,...
9913811 Hydroxynaphthoquinone compounds for treatment of non-small cell lung cancer  
A compound suitable for treating EGFR-dependent non-small cell lung cancer exceptionally inhibits activity of the EGFR kinase, in particular in EGFR-dependent non-small cell lung cancer with...
9913809 Anti-cancer activity of (E)-1-(3′,4′-dimethoxyphenyl) butadiene  
The present invention provides a method of using (E)-1-(3′, 4′-dimethoxyphenyl) butadiene to induce anti-tumorigenic effects in pancreatic carcinoma, ovarian carcinoma, prostate carcinoma, colon...
9909190 Method for assisting detection of pancreatic cancer  
Disclosed is the provision of a method for assisting the detection of pancreatic cancer, the method assisting the detection of pancreatic cancer with high accuracy. In the method for assisting the...
9909186 Personalized biomarkers for cancer  
The invention provides methods and reagents for identifying personalized tumor biomarkers for a patient that has a solid tumor and methods of using such biomarkers to monitor patient responses to...
9909185 Diagnosis and prognosis of breast cancer patients  
The present invention relates to genetic markers whose expression is correlated with breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to...
9909128 Splice modulating oligonucleotides that inhibit cancer  
A method of treating cancer in a subject is provided. The method includes administering a splice modulating oligonucleotide to the subject in an amount effective to provide a therapeutic benefit...
9908922 Peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
9908920 Peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
9907849 Combination of a PD-1 antagonist and a listeria-based vaccine for treating prostate cancer  
The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and a Listeria based strain that expresses prostate-tissue specific antigen...
9907842 Cytotoxic T lymphocyte inducing immunogens for prevention treatment and diagnosis of cancer  
The present invention relates to compositions and methods for the prevention, treatment, and diagnosis of cancer, especially carcinomas, such as lung carcinoma. The invention discloses peptides,...