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9605074 Multifunctional nanobodies for treating cancer  
The technology described herein is directed to methods and compositions directed to the treatment of cancer, e.g. using multifunctional receptor targeted cancer therapeutics.
9605043 Fusion protein for suppressing cancer cell growth and suppressing vasculogenesis, and anticancer composition comprising same  
The present invention relates to a fusion protein resulting from the fusion of a cancer-specific antibody and an angiogenesis inhibitor, and relates to an anti-cancer composition including the...
9604973 Anti-cancer polyketide compounds  
Provided herein, inter alia, are anticancer polyketides. The uses of the polyketides described herein include treatment of cancer, for example, through regulation of the spliceosome and detection...
9604950 Trail enhancers for the selective killing of cancer cells  
The invention is directed to methods of inducing apoptosis, arresting cell cycle, or inhibiting cellular proliferation, or any combination thereof, in a tumor cell, by administration of an...
9604937 Pyrimidine-2,4-diamine derivatives for treatment of cancer  
A compound of formula (I), or a pharmaceutically-acceptable salt thereof. The compound is useful in the treatment of cancer or other diseases that may benefit from inhibition of MTH1.
9603926 Histone deacetylase (HDAC) inhibitors for the treatment of cancer  
The present invention relates generally to methods for treating cancer. In one respect, the present invention relates to a method of treating a hematological cancer (e.g., multiple myeloma,...
9603913 Globo H and related anti-cancer vaccines with novel glycolipid adjuvants  
An immunogenic composition containing a glycan conjugate including a carrier protein, and a glycan including Globo H, an immunogenic fragment thereof, or stage-specific embryonic antigen-4...
9603912 Cancer therapy  
An agent that stimulates antiviral immunity may be used, for the treatment of cancer. A product comprising an immunostimulant and a vector comprising a transgene that promotes death of neoplastic...
9603873 Activation of innate immunity by miRNA for cancer and infection treatment  
Methods and compositions involving miR-122, miR-15b, miR-21, and miR-155, which are useful for the treatment of various diseases, such as cancers, are described. Further described are methods and...
9603835 Use of 3-(R)-[3-(2-methoxyphenylthio)-2-(S)-methylpropyl]amino-3,4-dihydro-2H-1,5-benzoxathiepine for treating cancer and in particular for preventing and/or treating cancer metastases  
The present invention relates to the use of 3-(R)-[3-(2-methoxyphenylthio)-2-(S)-methyl-propyl]amino-3,4 -dihydro-2H-1,5-benzoxathiepine or one of the pharmaceutically acceptable salts thereof for...
9599624 BARD1 isoforms in lung and colorectal cancer and use thereof  
The present invention relates to new BARD1 isoforms specific to lung cancer and colorectal cancer, a method for detecting thereof and a method for treating and/or preventing lung cancer and...
9599619 Anti-pancreatic cancer antibodies  
Described herein are compositions and methods of use of anti-pancreatic cancer antibodies or fragments thereof, such as murine, chimeric, humanized or human PAM4 antibodies. The subject antibodies...
9599618 Method, apparatus, system, program, and computer-readable recording medium for evaluating colorectal cancer  
According to the method of evaluating colorectal cancer of the present invention, amino acid concentration data on the concentration value of amino acid in blood collected from a subject to be...
9598470 Compositions and methods to prevent cancer by stabilizing P53 through non MDM2-mediated pathways  
The present invention relates to compositions and methods comprising chemopreventive agents that may be cupredoxin(s) or variants, derivatives and structural equivalents of cupredoxins, and at...
9598448 Osmium (II) arene imino anti-cancer complexes  
The present invention relates to the use of certain osmium containing complexes such as cytotoxic agents particularly for the treatment of cancer. There is also provided novel osmium containing...
9598416 Substituted benzothienyl-pyrrolotriazines and uses thereof in the treatment cancer  
This invention relates to novel substituted 5-(1-benzothiophen-2-yl)pyrrolo[2,1-fJ[1,2,4]triazin-4-amine derivatives having protein tyrosine kinase inhibitory activities, to processes for the...
9598351 Polyamine transporter selective compounds as anti-cancer agents  
Several aromatic hydrocarbons di-substituted with a polyamine are described according to formulas selected from compounds 4, 7, 10, 15 and pharmaceutically acceptable salts thereof. The novel...
9597409 Methods of treating cancer  
The present invention provides methods and compositions for treating non-small-cell lung cancer (NSCLC) by administering a) a composition comprising nanoparticles that comprise paclitaxel and an...
9597325 Inhibitors of late SV40 factor (LSF) as cancer chemotherapeutics  
The present invention is directed to methods, compositions and kits for treatment of cancer, e.g. heptacellular carcinoma. In some embodiments, the present invention discloses the use of a...
9597316 Indole compounds for use in treating inflammation and cancer  
Provided herein are compounds, comprising Formula (I) or Formula (II), and their pharmaceutically acceptable salts. Also provided are pharmaceutical compositions comprising a pharmaceutically...
9597299 Method for treating gefitinib-resistant non-small-cell lung cancer  
The present invention relates to a method for treating gefitinib-resistant non-small-cell lung cancer (NSCLC) comprising administering an effective amount of a resveratrol analog,...
9596834 Steatohepatitis-liver cancer model animal  
Fatty liver was induced by administering agents for inducing organ inflammation to experimental animals to evoke insulin resistance and by rearing them with high-fat diets. As a result,...
9594086 Biomarkers for aggressive prostate cancer  
The present invention relates to the field of biomarkers and, more specifically, to biomarkers useful in diagnosing aggressive prostate cancer. In specific embodiments, a method for diagnosing...
9593379 Composition and kit for diagnosing breast cancer including polynucleotide within vesicle, and method of diagnosing breast cancer using the same  
A breast cancer diagnostic composition and kit, and methods of diagnosing breast cancer or acquiring information for breast cancer diagnosis by using the composition or kit are provided. The...
9593377 Signatures and determinants associated with cancer and methods of use thereof  
The present invention provides methods of detecting cancer using biomarkers.
9593336 Compositions and methods for treating cancer and other diseases  
Aptamers and improved aptamers are provided with enhanced efficacy for binding to target molecules in vivo or for treating cancer or other diseases. Such improvements in aptamers are provided that...
9593162 Internalizing human monoclonal antibodies targeting prostate cancer cells in situ  
This invention provides a method that allows selection of antibodies against cells (e.g., tumor cells) in situ using laser capture microdissection. By restricting antibody selection to binders of...
9593146 CD44v6-derived peptides for treating metastasizing cancer  
The present invention relates to compounds, pharmaceutical compositions and methods for treating different forms of pancreatic cancer.
9593129 Piperidinone derivatives as MDM2 inhibitors for the treatment of cancer  
The present invention provides MDM2 inhibitor compounds of Formula I, wherein the variables are defined above, which compounds are useful as therapeutic agents, particularly for the treatment of...
9593062 Means and methods for treating and/or preventing natural AHR ligand-dependent cancer  
The present invention relates to the field of cancer therapeutics and treatment of cancer. In particular, it relates to a method for treating and/or preventing a natural AHR ligand-dependent...
9592292 Silicon nanoparticle for photodynamic cancer treatment utilizing quantum dot optical properties  
Quantum active sized silicon nanoparticles with a silicon core covered by a thin 0.5-1.5 nm oxide/nitride shell are described for light exposure in the 300-600 nm range for transforming...
9592290 Monoclonal antibody therapy for pancreas cancer  
The present invention relates to the use of binding equivalents of monoclonal antibody 31.1, including chimerized and/or humanized versions thereof, antibody fragments as well as competitively...
9592260 Cancer therapy with a parvovirus combined with an HDAC inhibitor  
Described is a pharmaceutical composition comprising (a) a parvovirus and (b) a histone deacetylase inhibitor (HDACI) and the use of said composition for treatment of cancer, e.g., brain tumor,...
9588127 Compositions, methods and kits for diagnosis of lung cancer  
Methods are provided for identifying biomarker proteins that exhibit differential expression in subjects with a first lung condition versus healthy subjects or subjects with a second lung...
9588122 Methods of treating cancer sensitive to anti-EGFR therapy and modifying treatment using peroxiredoxin 6 biomarker  
The present disclosure provides methods of treating cancer and modifying a cancer treatment for a cancer with an anti-EGFR drug by creating PRDX6 expression profiles and using the profiles to...
9588121 Method for early detection of cancer  
The present inventors have demonstrated that circulating auto-antibodies to cancer antigens hold promise as specific and sensitive biomarkers for the early detection of cancer. The present...
9588119 In vitro method of inhibiting the growth of radioresistant laryngeal cancer cells  
Disclosed are increased expression of ERp57, ERp57-STAT3 complex, and ERp57-STAT3-Mcl-1 in laryngeal cancer, especially in radioresistant laryngeal cancer and their regulations on radioresistance...
9587019 CD33 antibodies and use of same to treat cancer  
The invention provides murine, chimeric, and humanized antibodies that specifically bind to CD33. The antibodies are useful for treatment and diagnoses of various cancers as well as detecting CD33.
9586994 CD44V6-derived peptides for treating breast cancer  
The present invention relates to compounds, pharmaceutical compositions and methods for treating different forms of breast cancer.
9586993 CD44v6-derived peptides for treating pancreatic cancer  
Compounds, pharmaceutical compositions and methods for treating different forms of pancreatic cancer.
9586989 Non-toxic skin cancer therapy with copper peptides  
Methods are provided for administering compositions for topical dermatological treatment and resolution of skin cancer lesions in humans and domestic animals, including especially light skinned...
9586940 Methods for treatment of breast cancer nonresponsive to trastuzumab  
The present invention provides a method of treating breast cancer that is nonresponsive to treatment with trastuzumab, comprising administering to a subject in need of such treatment a...
9586056 Combination therapy for treating cancer and method for treating cancer using a combination therapy  
A combination therapy for treating cancer including a DNA damaging agent deliverable to cancer cells and operatively arranged to activate only under a low oxygen condition and a non-thermal plasma...
9585927 Herbal composition for treating metastatic breast cancer  
The invention provides a composition comprising a mixture of extracts obtained from Atractylodes macrocephala, Astragalus membranaceus, Taraxacum mongolicum, Poria cocos, Ligusticum chuanxiong,...
9585920 Method and system for treating cancer cachexia  
Various embodiments of the present invention are directed to the field of Oncology, and in particular, embodiments directed to a method of ameliorating, treating, or preventing a malignancy in a...
9585861 Method for treating a cancer with a mixed ligand gold(III) complexes as anti-cancer agents  
Gold(III) complexes with mixed ligands as anticancer agents. The gold(III) cations are coordinated to bidentate ligands having diamino functional groups: a diaminocyclohexane ligand and a...
9580756 Stratification of left-side and right-side colon cancer  
Compositions/methods for employing fresh-frozen or FFPE colon cancer tissue in left side colon cancer (LCC) and right-side colon cancer (RCC) disease patients for risk of relapse...
9580750 P13K pathway mutations in cancer  
Given the important role of protein kinases in pathways affecting cellular growth and invasion, we have analyzed 340 serine/threonine kinases for genetic mutations in colorectal cancers. Mutations...
9580438 Bifluorodioxalane-amino-benzimidazole kinase inhibitors for the treatment of cancer, autoimmuneinflammation and CNS disorders  
The invention relates to a compound of the general formula (I) or a physiologically functional derivative, solvate or salt thereof, wherein A, X, L, Y, R, and RN are as defined herein. The...
9580399 Geranyl flavonoid derivative with improved water solubility, a method for preparing the same, and a method for treating cancer using the same  
The present invention relates to a novel geranyl flavonoid derivative with improved water-solubility or a pharmaceutically acceptable salt thereof, a method for preparing the same, and a method...