|
Match
|
Document |
Document Title |
|
|
8183297 |
Medium and device for proliferation of stem cells and treatment of cancer-related stem cell with resveratrol
The invention relates to a device for selecting stem cells with a serum free medium for amplification of stem cells. The invention also relates to a method of treating or preventing diseases caused...
|
|
|
8183207 |
Treatment of osteolytic disorders and cancer using CSF1R extracellular domain fusion molecules
Methods of using colony stimulating factor receptor (CSF1R) extracellular domain (ECD) fusion molecules for treating osteolytic bone loss, cancer metastasis, cancer metastasis-induced osteolytic...
|
|
|
8183008 |
Evaluating MMP expression in patient stratification and other therapeutic, diagnostic and prognostic methods for cancer
Provided are compositions, methods and kits for quantifying the expression and/or activity of MMP-14 and other biomarkers of cancer, which may be used diagnostically and prognostically, e.g., in...
|
|
|
8182997 |
Prostate cancer related gene STYK1
The present invention provides methods for detecting and diagnosing cancer, which method involves the determination of the expression level of the STYK1 gene. The gene was discovered to...
|
|
|
8182823 |
Compositions and methods for the therapy and diagnosis of breast cancer
Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic...
|
|
|
8182816 |
Methods of treating cancer
Disclosed are methods of treating subjects having cancers including administering an effective amount of an early activation molecule agonist, antagonist or depletor, to the subject. Human...
|
|
|
8182809 |
Methods for treating cancer by inhibiting MIC shedding
Described herein are compositions and methods for treating cancer, comprising administering to an individual having cancer an agent to prevent MIC shedding (initiated at the alpha-3 ectodomain of...
|
|
|
8178859 |
Proton beam positioning verification method and apparatus used in conjunction with a charged particle cancer therapy system
The invention comprises a proton beam positioning method and apparatus used in conjunction with multi-axis charged particle radiation therapy of cancerous tumors. The proton beam verification...
|
|
|
8178727 |
Bis(arylmethylidene)acetone compound, anti-cancer agent, carcinogenesis-preventive agent, inhibitor of expression of Ki-Ras, ErbB2, c-Myc and Cycline D1, β-catenin-degrading agent, and p53 expression enhancer
It has been demanded to improve the poor solubility of curcumin to develop an anti-tumor compound capable of inhibiting the growth of various cancer cells at a low concentration. Thus, disclosed is...
|
|
|
8178564 |
Use of picoplatin to treat colorectal cancer
The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment...
|
|
|
8178545 |
Dual small molecule inhibitors of cancer and angiogenesis
The present invention provides analogs and derivatives of thalidomide which inhibit cancer and angiogenesis. The present invention further provides compounds which disrupt microtubule...
|
|
|
8178505 |
Method of predicting and reducing risk of metastasis of breast cancer to lung
A signature for breast cancer tissue derived from a patient is established that is indicative of the virulence and risk of lung metastasis by determining the expression levels to define a sample...
|
|
|
8178102 |
Emulsified composition for dilution and cancer vaccine composition
Provided is an emulsified composition for diluting a cancer antigen peptide or a dimer thereof. Also provided is a novel cancer vaccine composition or specific CTL inducer that efficiently induces...
|
|
|
8178096 |
Use of an anti-CD151 antibody in the treatment of cancer
The present invention relates to the use of at least one antibody, or a functional fragment thereof, which is capable of binding to the CD151 protein and thereby inhibiting tumor growth, in the...
|
|
|
8173789 |
Peptide having ability to activate cancer-related gene
To provide a cancer diagnostic reagent for determining malignancy of a cancer patient or a cancer cell and a tendency of canceration of a healthy subject, the reagent including a peptide having an...
|
|
|
8173788 |
Peptide having ability to activate cancer-related gene
To provide a cancer diagnostic reagent for determining malignancy of a cancer patient or a cancer cell and a tendency of canceration of a healthy subject, the reagent including a peptide having an...
|
|
|
8173780 |
Peptide having ability to activate cancer-related gene
To provide a cancer diagnostic reagent for determining malignancy of a cancer patient or a cancer cell and a tendency of canceration of a healthy subject, the reagent including a peptide having an...
|
|
|
8173686 |
Use of picoplatin to treat colorectal cancer
The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment...
|
|
|
8173619 |
***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Phosphoramidate derivatives of nucleoside compounds for use in the treatment of cancer
The compounds are phosphoramidate derivatives of nucleoside compounds such as cladribine, isocladribine, fludarabine and clofarabine useful in the treatment of cancer.
|
|
|
8173602 |
Detecting CYP24 expression level as a marker for predisposition to cancer
This invention pertains to the discovery that an amplification of the CYP24 gene or an increase in CYP24 activity is a marker for the presence of, progression of, or predisposition to, a cancer...
|
|
|
8173433 |
Platelet biomarkers for cancer
The present invention relates to the fields of immunology and biochemistry. Particularly, the present invention describes methods, devices and kits for early detection of clinical conditions having...
|
|
|
8173428 |
LNA oligonucleotides and the treatment of cancer
The present disclosure concerns LNA oligonucleotides having a (sub)sequence of the general formula 5′-(MeCx)(Tx)MeCxAsAstscscsastsgsgsMeCxAx(Gx)(c)-3′, and preferably of the general formula 5′-...
|
|
|
8173381 |
Nucleic acid and corresponding protein entitled 85P1B3 useful in treatment and detection of cancer
A novel gene (designated 85P1B3) and its encoded protein are described. While 85P1B3 exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in multiple cancers...
|
|
|
8173366 |
Genetic changes in ATM and ATR/CHEK1 as prognostic indicators in cancer
The present invention relates to the discovery that, in human cancer, an 11q deletion of ATM together with an increase in ATR and CHEK1 expression correlates with resistance to ionizing radiation...
|
|
|
8173177 |
Compositions of botanical extracts for cancer therapy
Methods and compositions for prevention and therapy of cancer are provided. Compositions comprising therapeutically effective amounts of two or more of an extract of Ganoderma lucidum, an extract...
|
|
|
8173132 |
Nucleic acid and corresponding protein entitled 213P1F11 useful in treatment and detection of cancer
A novel gene (designated 213P1F11) and its encoded protein, and variants thereof, are described wherein 213P1F11 exhibits tissue specific expression in normal adult tissue, and is aberrantly...
|
|
|
8173128 |
Methods and compositions for inducing apoptosis in cancer cells with an anti-DR5 antibody
Anti-DR5 antibody agonists, combined with apoptosis-inducing agents, synergistically induce apoptosis in cancer cells.
|
|
|
8173103 |
Inhibition of cancer metastasis
P-Selectin on platelets and endothelium binds cell surface chondroitin sulfate (CS) proteoglycans, which are abundantly and stably expressed on the surface many cancer cells. Binding of the cancer...
|
|
|
8168662 |
Use of picoplatin to treat colorectal cancer
The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment...
|
|
|
8168661 |
Use of picoplatin to treat colorectal cancer
The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment...
|
|
|
8168602 |
Compositions, kits and methods for identification, assessment, prevention and therapy of cancer
The invention relates to compositions, kits, and methods for detecting, characterizing, preventing, and treating human cancer. A variety of chromosomal regions (MCRs) and markers corresponding...
|
|
|
8168586 |
Cancer targets and uses thereof
Methods and compositions are provided for assessing, treating, and preventing diseases, especially cancer, using cancer-associated targets (“CAT”). Methods and compositions are also provided for...
|
|
|
8168427 |
Monoclonal antibodies against claudin-18 for treatment of cancer
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric...
|
|
|
8168404 |
Methods to treat cancer with 10-propargyl-10-deazaaminopterin and methods for assessing cancer for increased sensitivity to 10-propargyl-10-deazaaminopterin
The present invention relates to a method for assessing the sensitivity of a patient's cancer to treatment with 10-propargyl-10-deazaminopterin and a method for selecting a patient for treatment of...
|
|
|
8168238 |
Extracts of Aquilaria hulls and use thereof in the treatment of cancer
The invention discloses an ethyl acetate layer of methanol extract of Aquilaria hulls for killing cancer cells and treating/preventing cancers and its uses. The extracts of Aquilaria hulls has an...
|
|
|
8168232 |
Formulations and methods of using nitric oxide mimetics in cancer treatment
The present invention relates to methods and formulations for inhibiting, treating and preventing a malignant cell phenotype, cell, tumor and/or disease. Administration of nitric oxide mimetics,...
|
|
|
8168216 |
Treatment of triple receptor negative breast cancer
The present invention relates to the use of a liposomal preparation for the manufacture of a pharmaceutical composition and the use of such a composition for the treatment of ‘triple receptor n...
|
|
|
8168187 |
Nucleic acid and corresponding protein entitled 184P1E2 useful in treatment and detection of cancer
A novel gene (designated 184P1E2) and its encoded protein, and variants thereof, are described wherein 184P1E2 exhibits tissue specific expression in normal adult tissue, and is aberrantly...
|
|
|
8163883 |
Gene encoding labyrinthin, a marker for cancer
A cDNA molecule that encodes a protein designated Labyrinthin (Lab) isolated and its nucleotide sequence is determined. The protein, or peptides derived from the protein, are markers useful to...
|
|
|
8163796 |
Treatment of cancer by oxidation-reduction potentiation of cancerostatic dicarbonyls
A novel treatment regimen is described for the control and elimination of cancer cell populations including cancer stem cells. The disclosed protocol consists of a pretreatment step followed by a...
|
|
|
8163744 |
Tetrahydro-isoquinolin-1-ones for the treatment of cancer
The present invention provides a compound selected from compounds of formula I as ligand binding to the HDM2 protein, inducing apoptosis and inhibiting proliferation, and having therapeutic utility...
|
|
|
8163709 |
TAK1-D mediated induction of cell death in human cancer cells by specific sequence short double-stranded RNAS
The splicing variant D of the TAK1 gene is activated by short double-stranded RNAs in a sequence specific manner. Activation of TAK1-D leads to the downstream activation of the p38 MAPK and of...
|
|
|
8163509 |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
The present invention provides diagnostic methods for predicting the effectiveness of treatment of a cancer patient with an IGF-1R kinase inhibitor. Methods are provided for predicting the...
|
|
|
8163499 |
Drug selection for breast cancer therapy using antibody-based arrays
The present invention provides compositions and methods for detecting the activation states of components of signal transduction pathways in tumor cells. Information on the activation states of...
|
|
|
8163494 |
Method for assessing metastatic properties of breast cancer
Methods and compositions suitable for modulating angiogenesis in a mammalian tissue are provided. Further provided are methods suitable for inhibiting metastasis and fibrosis in a mammalian tissue...
|
|
|
8163493 |
Targets for use in diagnosis, prognosis and therapy of cancer
Provided herein are targets that can be used for the diagnosis, prognosis and therapy of a variety of cancers.
|
|
|
8163476 |
CUDR as biomarker for cancer progression and therapeutic response
Disclosed is a novel human gene designated CUDR. Provides is also a CUDR gene as a biomarker in the diagnosis of human cancers and a cancer therapy.
|
|
|
8163473 |
Method for using DNA repair capacity as a biomarker of breast cancer risk in women
The present invention presents a method for using DNA repair capacity (DRC) as a blood biomarker to calculate the risk of a female subject developing breast cancer obtained from a blood sample by...
|
|
|
8158761 |
Wnt proteins and detection and treatment of cancer
The present specification provides, inter alia, methods of using Wnt and FZD proteins, genes, FZD and Wnt-specific antibodies and probes in diagnosis and treatment of cancer and for screening test...
|
|
|
8158758 |
Compositions and methods for treating and diagnosing cancer
The present invention relates to compositions and methods for characterizing, diagnosing and treating cancer. In particular, the present invention identifies LGR5 as a protein over-expressed in...
|