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9884051 Demethylpenclomedine analogs and their use as anti-cancer agents  
This disclosure concerns novel demethylpenclomedine analogs. Also disclosed are pharmaceutical compositions and methods for using such compositions to treat hyperproliferative disorders. In one...
9884047 Method of treating lung cancer  
One example embodiment relates to a method of treating non-small cell lung cancer by administering a compound of formula (I) to a patient. Another example embodiment relates to a method of...
9884046 Method of treating lung cancer  
One embodiment relates to a method of treating lung cancer by administering a compound of formula I to a patient. Another embodiment relates to a method of treating cancer with a KRAS mutation...
9884040 Desethylamiodarone for use in cancer treatment  
The invention relates to a compound selected from the group consisting of desethylamiodarone and pharmaceutically acceptable salts, hydrates and solvates thereof, as well as pharmaceutical...
9884028 Methods for treatment of bladder cancer  
Apparatus and methods for treatment of an internal cavity are provided. The internal cavity is coated with a treatment solution. The treatment solution can include a solidifiable matrix with or...
9881371 System for visualization of a cancer diagnosis  
Certain aspects of an apparatus and method for automatic ER/PR scoring of tissue samples may include for determining a cancer diagnosis score comprising identifying a positive stained nucleus in a...
9879324 Genetic determinants of prostate and breast cancer risk  
Described are methods of determining if a subject has a genetic predisposition to developing prostate cancer (PCa) or aggressive PCa, or to developing breast cancer (BrCa).
9879227 Diffusible factors and cancer cells  
The present invention relates to modified cancer cells that are defective in the production of diffusible factors (e.g., growth factors), and to the use of such cells for impairing the growth of a...
9878998 Barbiturate and thiobarbiturate compounds for use in cancer therapy  
Provided are methods and compositions for use in therapy, and in particular for treating cancer, preferably drug-resistant cancer, and/or radiation resistant cancer. The compounds may be used for...
9878993 DNA-PK inhibitors for treatment of cancer  
The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the...
9878984 Anti-cancer compounds  
The present invention relates to anti-cancer compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides analogs of the known anti-cancer...
9878174 High frequency cancer thermotherapy apparatus  
A high frequency cancer thermotherapy apparatus treats by generating a high frequency electric field between a pair of electrode parts which sandwich a patient and are disposed so as to be...
9878049 High drug loading system to co-deliver anticancer drugs and nucleic acids for cancer therapy  
A high drug loading system is described comprising of at least one anticancer drug; at least one peptide; and at least one nucleic acid.
9878015 Pharmaceutical compositions and methods for the treatment of metastatic cancer  
The invention provides isolated peptides, fragments and derivatives thereof and pharmaceutical compositions comprising same that are useful for the prevention or treatment of cancer metastasis.
9877999 Methods for treating metastatic stage prostate cancer  
The invention provides methods and dosing regimens for eating metastatic stage prostate cancer in a subject using degarelix, as well as related methods of using degarelix in a subject identified...
9877981 NAD biosynthesis and precursors for the treatment and prevention of cancer and proliferation  
Disclosed herein are novel compositions and methods for the treatment of age-related diseases, mitochondrial diseases, the improvement of stress resistance, the improvement of resistance to...
9877978 Compositions comprising NDGA derivatives and sorafenib and their use in treatment of cancer  
The present invention provides pharmaceutical compositions comprising derivatives of NDGA, including M4N (tetra-O-methyl nordihydroguaiaretic acid) and sorafenib and their use in the inhibition...
9877962 Piperazinyl derivatives for the treatment of cancer  
Piperazinyl derivatives of formula (I) and their use as a drug, particularly for the treatment of cancer, are disclosed. Also disclosed are pharmaceutical compositions comprising the piperazinyl...
9877958 Apoptosis-induced agents for the treatment of cancer and immune and autoimmune diseases  
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed...
9877944 Use of a composition comprising fish oil and juice for the treatment and/or post treatment of cancer  
Disclosed is a composition including a fish oil and a juice in an oil-in-water emulsion for use in treatment and post-treatment of cancer.
9873916 Method for predicting response to trastuzumab therapy in breast cancer patients  
This invention relates to a composition and a method for prediction of a response to Trastuzumab therapy in a breast cancer patient, and more specifically, a composition, a kit, a DNA chip, and a...
9873915 Grading, staging and prognosing cancer using osteopontin-C  
The present disclosure provides methods and kits that can be used to determine the grade or stage of a breast or other cancer, such as a ductal carcinoma in situ (DCIS). By determining the grade,...
9873878 Compositions and methods for use in treating silicosis and lung cancer  
A method for treating an inflammatory disease is provided. The method comprises administering an effective amount of a BLT1 inhibitor to a subject in need thereof. The BLT1 inhibitor is selected...
9873876 Cancer treatment  
In certain embodiments, methods, compounds, and compositions for treating B-cell lymphoma or hepatocellular carcinoma by inhibiting expression of ST AT3 mRNA or protein in an animal are provided...
9873747 Fusion proteins that facilitate cancer cell destruction  
Provided is a fusion protein comprising a polypeptide component that blocks binding of CD47 to SIRP alpha and a polypeptide that binds to and triggers a TRAIL receptor or Fas. Also provided is a...
9873740 Methods of treating cancer using PD-1 axis binding antagonists and TIGIT inhibitors  
The present invention describes combination treatment comprising a PD-1 axis binding antagonist and an agent that decreases or inhibits TIGIT expression and/or activity and methods for use...
9873718 Structure-based peptide inhibitors of P53 aggregation as a new approach to cancer therapeutics  
This invention relates, e.g., to an inhibitory peptide or CPP inhibitor which specifically binds to p53 having an aberrant conformation (e.g., is aggregated or misfolded) and inhibits p53...
9873711 Multimeric dual-modality breast cancer diagnostic agents  
The present invention describes dual-modality probes. In particular, the present invention discloses hydroxyapatite specific multimeric bisphosphonate dual-modality MRI and optical probes.
9873699 Anti-cancer agents  
An anti-cancer agent having the formula: wherein Ph is a phenyl group and Ar is an aromatic group independently selected from the group consisting of phenyl, 2-bromophenyl, 4-bromophenyl,...
9873670 Arylquinoline and analog compounds and use thereof to treat cancer  
The subject technology relates to arylquinoline compounds and their use for treating cancer or cancer metastasis. The compounds of the subject technology promote cells to secrete a pro-apoptotic...
9872928 Diagnostic agent for therapeutic effect on cancer  
The present invention provides a diagnostic agent for a therapeutic effect on cancer, containing a compound represented by formula (1-0). (In formula (1-0), R represents —O(CH2)n—, —O(CH2)nOC2H4—,...
9872925 Vitamin B6-coupled poly(ester amine) as gene carrier and application in cancer gene therapy  
The present invention relates to a vitamin B6-coupled poly(ester amine) (VBPEA) as a gene carrier and a method for preparing the gene carrier. Moreover, the present invention relates to a gene...
9872921 DE-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy  
The present invention generally provides compositions methods and composition relating to the diagnosis and/or treatment of cancers having a cell surface de-N-acetylated sialic acid antigen, e.g.,...
9872912 Method for treating pancreatic cancer  
A method for treating pancreatic cancer is provided. The method comprises administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical formulation, wherein the...
9872909 Method for enhancing specific immunotherapies in cancer treatment  
Methods and compositions of the invention relate to the enhancement of specific immunotherapies in cancer treatment. In particular, aspects of the invention relate to novel approaches to boost...
9872903 Targeting thymidine kinase photosensitizer and pharmaceutical composition and use for cancer treatment thereof  
A targeting thymidine kinase photosensitizer and pharmaceutical composition and use for cancer treatment thereof is provided, which improves the selectivity of photosensitizers to tumor cells, has...
9872891 Peptides for the treatment of cancer  
The present invention relates to an isolated peptide for use in the treatment of cancer consisting of 12 to 50 amino acid residues comprising: at least two beta-strands, or at least two...
9872868 Mitochondrially-targeted electrophilic compounds and methods of use for the treatment of cancer  
The present invention provides methods, compounds, compositions and kits including mitochondrially-targeted electrophilic (MTE) compounds that are useful for treating cancer.
9869677 Methods of developing a prognosis for pancreatic cancer and predicting responsiveness to cancer therapeutics  
Methods of predicting responsiveness of a cancer in a subject to a cancer therapy including a VEGF targeting agent are provided herein. The methods include detecting the expression level of at...
9868993 Methods of diagnosing or treating prostate cancer using the ERG gene, alone or in combination with other over or under expressed genes in prostate cancer  
The present invention relates to oncogenes or tumor suppressor genes, as well as other genes, involved in prostate cancer and their expression products, as well as derivatives and analogs thereof....
9868992 Tissue and blood-based miRNA biomarkers for the diagnosis, prognosis and metastasis-predictive potential in colorectal cancer  
Methods and compositions for the diagnosis, prognosis and classification of cancer, especially colorectal cancer, are provided. For example, in certain aspects methods for cancer prognosis using...
9868954 Reduction of TGFβ signaling in myeloid cells in the treatment of cancer  
Methods of inhibiting metastasis in cancer patients are provided, wherein the methods comprise reducing TGFβ signaling, for example, by reducing TGFβ receptor II expression in myeloid cells....
9868784 Antibodies against the S100P protein for the treatment and diagnosis of cancer  
The present invention relates to the use of antibodies against the S100P protein for the prevention and/or treatment of cancer; and to methods and kits for diagnosing cancer in vitro by means of...
9868705 Tetra-aryl cyclobutane inhibitors of androgen receptor action for the treatment of hormone refractory cancer  
The present disclosure provides tetra-substituted cyclobutane inhibitors of Androgen Receptor Action, and methods of using such inhibitors, for the treatment of hormone-refractory cancers.
9867865 Mesalamine for the treatment of cancer  
Methods of treating renal cancer, including renal cell carcinoma, using mesalamine are disclosed herein. Mesalamine can be administered as a monotherapy or as part of a comprehensive treatment...
9867807 Compositions and methods for drug-sensitization or inhibition of a cancer cell  
The disclosure provides rifamycin and rifamycin derivative compositions, including rifabutin and rifabutin derivative compositions able to cause drug-sensitization in a cancer cell or inhibition...
9863960 Method, array and use for determining the presence of pancreatic cancer  
The present invention relates to a method for determining the presence of pancreatic cancer in an individual comprising or consisting of the steps of: (a) providing a sample to be tested from the...
9863953 Method for determining prognosis of cancer  
The present invention relates to a method for determining prognosis of cancer in a subject, which comprises the step of detecting phosphorylation of a tyrosine residue at position 2681 of TRIO in...
9863949 Method for predicting and evaluating responsiveness to cancer treatment with DNA-damaging chemotherapeutic agents  
Provided herein are methods directed to the prediction and early assessment of the efficacy of cancer treatment regimens, in particular in patients undergoing therapy with a DNA-damaging...
9863005 Endometrial phase or endometrial cancer biomarkers  
Methods for detecting endometrial diseases or an endometrium phase in a subject are described comprising measuring endometrial markers or polynucleotides encoding the markers in a sample from the...