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9624547 Salivary transcriptomic and proteomic biomarkers for breast cancer detection  
Presented herein are biomarkers related to breast cancer. The presently identified salivary biomarkers create the basis for a breast cancer detection bioassay with sensitivity and specificity....
9624511 Specific TT virus sequences and chimeric TT virus host cell DNA molecules for use in diagnosis, prevention and treatment of cancer and autoimmunity  
Described are single-stranded new sequences of TT viruses, rearranged TTV sequences and hybrid molecules of a specific TT virus sequence and host cell DNA that are capable of replicating...
9624491 Methods and compositions for the detection and treatment of cancer involving miRNAs and miRNA inhibitors and targets  
The present invention relates to microRNAs (miRNAs) which are associated with cancer, particularly including hematologic malignancies, and particularly T-cell acute lymphoblastic leukemia (T-ALL),...
9624306 Anti-epidermal growth factor receptor variant III chimeric antigen receptors and use of same for the treatment of cancer  
The invention provides chimeric antigen receptors (CARs) comprising an antigen binding domain of human antibody 139, an extracellular hinge domain, a transmembrane domain, and an intracellular...
9624284 Cytotoxic T lymphocyte inducing immunogens for prevention treatment and diagnosis of cancer  
The present invention relates to compositions and methods for the prevention, treatment, and diagnosis of cancer, especially carcinomas, such as pancreatic carcinoma. The invention discloses...
9624211 Anti-cancer compounds  
Provided are methods and compositions for the treatment of diseases such as cancer. In certain aspects, compounds which can inhibit Skp2 are provided. Specifically chromenone derivatives are...
9623128 Compositions and methods for detecting plectin-1 as a biomarker for cancer  
The present invention provides compositions and methods useful for diagnostic and imaging techniques for detecting and localizing the biomarker Plectin-1. The present invention provides multimeric...
9623124 Multimodal diagnostic technology for early stage cancer lesions  
Disclosed herein are compositions of a multimodal detection agent and methods of fabricating the same. The multimodal detection agent comprises a plurality of metallic nanoparticles attached to a...
9623116 Antibody-light fusion products for cancer therapeutics  
Antibody-LIGHT fusion products or conjugates stimulate immunity against tumors and eradicate metastases. Tumor-specific antibodies coupled with LIGHT effectively target metastatic tumors and...
9623109 Methods of killing cells and use of same in prevention and treatment of cancer  
A method of killing a cell having a mutation in an Adenomatous polyposis coli (APC) gene is disclosed. The method comprises contacting the cell with an inhibitor of Casein kinase I (CKI), the CKI...
9623079 Methods for achieving therapeutically effective doses of anti-CD47 agents for treating cancer  
Methods are provided for treating a subject with a therapeutic dose of anti-CD47 agent by administering a primer agent prior to administering a therapeutically effective dose of an anti-CD47 agent...
9623032 Methods and compositions related to glucocorticoid receptor antagonists and breast cancer  
Embodiments of the invention are directed to methods of determining the prognosis of a breast cancer patient by evaluating the activity of the glucocorticoid receptor in tumor cells. Other...
9623031 Compositions, methods and kits for treating cancer  
Compositions, kits and methods for treating leukemia in a subject (e.g., human) include a first anti-cancer drug consisting of: Δ12-prostaglandin J3 or a derivative thereof, or a prostaglandin D...
9623028 Methods of treating a cancer using substituted pyrrolopyrimidine compounds, compositions thereof  
Provided herein are methods for treating or preventing a cancer, in particular solid tumors and hematological cancers, comprising administering to a subject in need thereof an effective amount of...
9623015 Combination of an anti-cancer agent such as a tyrosinekinase inhibitor and a STAT5 antagonist, preferably a thiazolidinedione, for eliminating hematologic cancer stem cells in vivo and for preventing hematologic cancer relapse  
Provided are methods for eliminating hematologic cancer stem cells in vivo, and thus preventing cancer relapse. The methods comprise a Signal Transducer and Activator of Transcription 5 (STAT5)...
9623009 Veliparib in combination with carboplatin and paclitaxel for the treatment of non-small cell lung cancer in smokers  
This invention pertains to a method for the treatment of non-small cell lung cancer in a subject who is a smoker, comprising administering to the subject an effective amount of...
9623004 Administration of a therapeutic amount of genistein to mitigate erectile dysfunction resulting from radiation therapy for prostate cancer only throughout a defined administration period commencing shortly before and concluding after radiation therapy  
A method for mitigating erectile dysfunction as an adverse side effect of radiation therapy for prostate cancer, comprising administration of a therapeutic dosage of genistein to a patient...
9622996 Use of adrenergic beta-E-receptor blockers in cancer treatment  
A method for treating an cancer disease is disclosed comprising administering to a subject a pharmaceutical composition comprising an adrenergic beta-3-receptor blocker.
9622990 Method for inhibiting cancer cell growth  
Disclosed is a method for inhibiting cancer cell growth in a subject in need thereof, comprising administering to the subject an effective amount of a compound from Antrodia camphorata, wherein...
9622987 Synergistic pharmaceutical composition useful for the treatment of lung cancer  
The present invention relates to a synergistic pharmaceutical composition comprising Compound C2 (Neo-isopulegol), C3 (Iso-pulegol) and C4 (Citronellol) derived from herbal seed extract of Litsea...
9622982 Cancer drug and uses  
A pharmaceutical composition comprising a cancer therapeutic that is capable of inhibiting and/or reducing the ability of a cancer cell to take up and utilize glucose or other energy source, a...
9618513 Compositions and methods for detecting and treating colorectal cancer  
The present invention relates to compositions and methods for the detecting, treating, and empirically investigating the interaction between a subject's immune system and cancer stem cells. In...
9618512 Biomarker for breast cancer  
A method for the diagnosis of breast cancer using an anti-LAT1 monoclonal antibody. Among intraductal breast neoplastic lesions, duct carcinoma in situ, which is malignant, expresses LAT1 at a...
9617603 Method for the urinary detection of bladder cancer  
The invention relates to the diagnosis of bladder cancer and more specifically to the detection in urine samples of bladder carcinomas of the transitional type. The detection method according to...
9617601 Materials and methods for diagnosis, prognosis and assessment of therapeutic/prophylactic treatment of prostate cancer  
A method to detect prostate cancer comprising contacting a sample of prostate cells from the patient with a set of detectably labeled probes under hybridization conditions and determining the...
9617599 Method for detection of cancer based on spatial genome organization  
The invention provides methods of detecting abnormal cells in a sample using the radial position of one or more genes within the nucleus of a cell, as well as a kit for detecting abnormal cells...
9617545 Method for treating breast cancer by targeting breast cancer stem cell  
The present invention relates to a composition for inhibiting growth of cancer stem cells, which includes an EXT1, LDHB, CD109, EFEMP2, RASIP1 or SERPINE1 gene expression inhibitor as an active...
9617349 Anti-cancer antibodies with reduced complement fixation  
The invention provides modified antibodies directed against GD2 that have diminished complement fixation relative to antibody-dependent, cell-mediated cytotoxicity, which is maintained. The...
9617340 Compositions and methods for diagnosing and treating cancer  
Isolated antibodies that specifically binds to an extracellular conserved ligand binding region of a human Notch receptor and inhibits growth of a tumor are described. Also described are methods...
9617336 C10RF32 antibodies, and uses thereof for treatment of cancer  
This invention relates to C1ORF32-specific antibodies, antibody fragments, alternative scaffolds, conjugates and compositions comprising same, for treatment of cancer.
9617304 Pharmaceutical composition containing an endocytic motif and protein transduction domains for preventing or treating cancer  
The present invention relates to a novel endocytic motif, and in particular, to a fusion polypeptide including the motif represented by an amino acid sequence of SEQ ID NO. 1 and a protein...
9617221 Kinase modulators for the treatment of cancer  
A method of treating cancer in which a compound that inhibits the expression, production or release of IL-10 by immune cells is combined with a compound that stimulates the production of IL-12...
9616252 Multi-field cancer therapy apparatus and method of use thereof  
A multi-field cancer therapy apparatus and method of use thereof is described increasing dimensionality of incident tumor treatment angles while minimizing distance between a final beamline...
9616072 Reduction of side effects from aromatase inhibitors used for treating breast cancer  
The present invention is directed generally to pharmaceutical compositions, methods, and kits for improving side effects associated with aromatase inhibitor treatment in a subject diagnosed with...
9616047 Inhibitors of beta-catenin in treatment of colorectal cancer  
Compounds are disclosed which are effective for inhibiting β-catenin or disrupting a β-catenin/Tcf-4 complex, and for causing effective attenuation of colon carcinogenesis. The compounds may be...
9616043 Taxane analogs for the treatment of brain cancer  
Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or...
9612243 Methods and compositions for targeted two-dimensional western blot analysis for early cancer detection and cancer diagnosis up to ten years in advance of clinical symptoms of malignant disease  
The present invention includes methods for detecting benign to malignant transformation of a cancer in a subject, comprising the steps of: collecting a sample from the subject prior to...
9611514 Method for selection of hDIS3 PIN domain inhibitors and use of hDIS3 PIN domain inhibitors for cancer treatment  
The present invention relates to a method for selection or screening of hDIS3 PIN domain inhibitors, yeast strain and cell line used in such methods It also relates to new therapeutic agents...
9611476 Cancer treatment methods using remote conditioning  
Cancer treatment methods comprising a step of applying remote conditioning to the cancer subject, for example remote ischemic conditioning via several episodes of short-term limb occlusion....
9611330 Compositions and methods for cancer and cancer stem cell detection and elimination  
In alternative embodiments, the invention provides compositions and methods for inhibiting or ablating cancer stem cells. In alternative embodiments, the invention provides compositions and...
9610366 Method for diagnosing cancer  
Methods for identifying the presence of cancerous cells or tissue by: applying a compound of formula (I), or salts thereof, to a living body, wherein R1 represents hydrogen or the same or...
9610348 Compositions and methods for treating and diagnosing cancer  
The present invention relates to compositions and methods for characterizing, diagnosing and treating cancer. In particular, the present invention identifies LGR5 as a protein over-expressed in...
9610319 Method of treating cancer  
A method of treating liver cancer using a peptide based on venom from a terebrid snail, terebrid variegata, is described. The venom has a general formula of TRX3CCGCYWNGSKDVCSQSCC (SEQ ID NO: 1)...
9610316 Medical composition for inhibiting the growth of cancer stem cells  
A medical composition for inhibiting the growth of cancer stem cells is disclosed. The medical composition is prepared by mixing herbal medicines with water or alcohol, followed by heating and...
9610256 Methods of use for 2,5-dihydroxybenzene sulfonic acid compounds for the treatment of cancer  
The invention describes compositions and methods of use for 2,5-dihydroxybenzene sulfonic acid compounds and pharmaceutically acceptable salts thereof. The invention provides methods for (a)...
9606123 Compositions and methods for diagnosing and monitoring ovarian cancer progression and treatment  
The present invention provides compositions and methods useful for diagnosing, monitoring the progression, identifying the location, and monitoring the treatment response in ovarian cancer based...
9606122 Prognosis of oesophageal and gastro-oesophageal junctional cancer  
The present invention relates to a method of aiding in the prognosis of a subject with oesophageal and/or gastro-oesophageal junctional (GOJ) adenocarcinoma, the method comprising the steps of:...
9606107 Crk—a novel target for cancer therapy  
The invention features a method of identifying a therapeutically active compound that inhibits apoptotic compensatory signaling complex (ACSC)-induced cell proliferation.
9605319 Gene signatures for cancer diagnosis and prognosis  
Biomarkers and methods using the biomarkers for molecular detection and classification of disease and, particularly, molecular markers for cancer diagnosis and prognosis and methods of use thereof...
9605317 Biomarkers for assessing peripheral neuropathy response to cancer treatment  
The present invention provides methods for identifying patients at increased risk of developing an adverse neurological event in response to a cancer treatment. Methods also include modifying the...