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9783855 Cancer screening by detection of ultrastructural and molecular markers  
The present invention relates to detection of cancer, or assessment of risk of development thereof. In particular, the present invention provides compositions and methods detection of field...
9783853 Recurrent gene fusions in cancer  
The present disclosure relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present disclosure relates...
9783808 Ovarian cancer-specific aptamers and applications thereof  
The present invention provides ovarian cancer-specific aptamers, which are selected in vitro using SELEX and a microfluidic chip system. The aptamers can also bind to different...
9783795 Multi-epitope peptide-loaded dendritic cell immunotherapy for cancer  
Peptides of from about 7 to about 50 amino acid residues in length that have epitopes that bind to more than one HLA class II protein and stimulate CD4+ T cells for treatment of cancer from one of...
9783615 Combination treatment of cancer  
The present invention provides MT4-MMP inhibitor and EGFR inhibitor for use in the treatment of cancer, wherein said MT4-MMP inhibitor and EGFR inhibitor are different from each other. MT4-MMP...
9783608 Humanized antibodies to LIV-1 and use of same to treat cancer  
The invention provides humanized antibodies that specifically bind to LIV-1. The antibodies are useful for treatment and diagnoses of various cancers as well as detecting LIV-1.
9783519 Palladium/silver co-catalyzed tandem reactions synthesis of phenylacetophenone derivatives by oxabenzonorbornadienes with terminal alkynes and their anti-tumor or anti-cancer activities  
This invention relates to the quick and efficient synthesis of anti-tumor or anti-cancer compounds. More particularly, it relates to the quick and efficient synthesis of anti-tumor or anti-cancer...
9782427 Methods for treating cancer using TOR kinase inhibitor combination therapy  
Provided herein are methods for treating or preventing a cancer, comprising administering an effective amount of a TOR kinase inhibitor having the following formula (I): and an effective amount of...
9782418 Rationale-based design of a targeted therapy for cancer  
The methods, compositions, and kits of the invention are related to the discovery that lestaurtinib reduces levels and pathway activity of an SPOP substrate. Accordingly, described herein are...
9782409 Treatment of cancer and benign proliferative disorders  
Disclosed herein are compositions comprising lopinavir alone or in combination with ritonavir for use as a medicament in the treatment of cancer or benign proliferative disorders (warts) or in the...
9782393 Pharmaceutical compositions and methods for treating cancer and biomarkers for drug screening  
A pharmaceutical composition comprising sorafenib and GW5074. Said combination therapy inhibits cancer cell growth via c-Raf-PP2A-DAPK signaling transduction pathway in either in vitro or in...
9782380 Method for treating ovarian cancer and/or Hodgkin lymphomia with a gold(III) complex  
A method for treating cancer and gold(III) complexes with diaminocyclohexane ligand as anticancer agents. Also described are a pharmaceutical composition incorporating the gold(III) complexes and...
9779499 Grading of glandular tissue cancer by detailed image analysis of stained tissue slices  
An improved histopathological score is obtained by identifying objects in images of glandular tissue from cancer patients. The objects are identified based on staining by a biomarker. The score...
9779283 Automated prostate tissue referencing for cancer detection and diagnosis  
This application provides to a method for identifying one or more prostate tissue samples in a database that are closest to a test prostate sample, which can be used to aid pathologists when...
9779213 System for evaluating a pathological stage of prostate cancer  
Clinical information, molecular information and/or computer-generated morphometric information is used in a predictive model for predicting the occurrence of a medical condition. In an embodiment,...
9779204 Predictive test for aggressiveness or indolence of prostate cancer from mass spectrometry of blood-based sample  
A programmed computer functioning as a classifier operates on mass spectral data obtained from a blood-based patient sample to predict indolence or aggressiveness of prostate cancer. Methods of...
9777334 Cancer blood test using BC200 RNA isolated from peripheral blood for diagnosis and treatment of invasive breast cancer  
Compositions and methods for diagnosing an increased risk for the development of aggressive, invasive breast cancer are provided.
9777068 Method for treating a GD2 positive cancer  
The present invention relates to a method for treating a GD2 positive cancer by administering a preparation comprising an anti-GD2 antibody to a patient as a continuous intravenous infusion over...
9777061 Treatment of cancer using a CD33 chimeric antigen receptor  
The invention provides compositions and methods for treating diseases associated with expression of CD33. The invention also relates to chimeric antigen receptor (CAR) specific to CD33, vectors...
9776989 Chromone alkaloid dysoline for the treatment of cancer and inflammatory disorders  
The present invention relates to novel chromone alkaloid of formula 1 isolated from the plant Dysoxylum binectariferum. The compound...
9775916 Anti-DLL3 antibody drug conjugates for treating cancer  
Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
9772286 Method for detection of urothelial cancer  
It is to provide a method for detecting urothelial cancer simply and with high accuracy. It is a method for detecting urothelial cancer comprising administering 5-aminolevulinic acid (ALA), a...
9771625 Monoamine oxidase inhibitors and methods for treatment and diagnosis of prostate cancer  
A mechanism of monoamine oxidases (MAOs) driven epithelium-to-mesenchymal transition (EMT) is disclosed. Also disclosed are methods for treating cancer by inhibiting or suppressing MAOs in cancer...
9771621 Method and kit for performing a colorectal cancer assay  
The present invention relates to method and kit for performing a colorectal cancer assay. Especially a method including extracting total RNA from a peripheral blood sample obtained from a patient...
9771618 Methods for treating breast cancer  
Clinical tests for testing therapeutic sensitivity of cancerous breast tissue and methods and kits for performing the same are described herein. Embodiments of the present invention are directed...
9771411 Method of treating cancer by administering EGFR and EGFR/IGFIR binding molecules  
The present invention relates to bispecific molecules comprising an EGFR binding domain and a distinct IGFIR binding domain for use in diagnostic, research and therapeutic applications. The...
9771404 Multi-level specific targeting of cancer cells  
A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13Rα2 binding ligand; at least one effector molecule (e.g., one, two, three or more...
9771356 Inhibitors of beta-hydroxylase for treatment of cancer  
The present invention relates to compounds which modulate (e.g., inhibit) the activity of beta-hydroxylase (e.g., Asparatyl (asparaginyl) β-hydroxylase (ASPH)), including novel...
9771347 Process for making compounds for use in the treatment of cancer  
Disclosed herein is a process of making a compound of formula I The compound of formula I is an inhibitor of MEK and thus can be used to treat cancer.
9771330 Pyrimidine compounds for the treatment of cancer  
Compounds of Formula I or II: are described, along with pharmaceutical compositions containing the same and methods of using such compounds for the treatment of cancer.
9770499 MSI-specific frameshift peptides (FSP) for prevention and treatment of cancer  
Described is a vaccine for prevention and treatment of cancer characterized by microsatellite instability (MSI). The vaccine contains an MSI-specific frameshift peptide (FSP) generating humoral...
9770482 Targeting the EGFR-SGLT1 interaction for cancer therapy  
A compound can destabilize an epidermal growth factor receptor (EGFR) protein and a sodium/glucose co-transporter 1 (SGLT 1) protein. In one embodiment, the compound is a peptide derived from the...
9770467 Compositions and methods for cancer immunotherapy  
The present invention provides a combination therapy which relies on a small molecule immune stimulator—cyclic-di-nucleotide (CDN)—that activates DCs via a recently discovered cytoplasmic receptor...
9770462 Method of treating ovarian, tubal and peritoneal cancer  
A method of treating ovarian, tubal and peritoneal cancer is revealed. It comprises administering an effective amount of a pharmaceutical composition (including a copper chelator, a platinum-based...
9770458 Anti-cancer agent containing a diacylphosphatidylethanolamine as an active ingredient  
The present invention provides an anti-cancer agent, a cancer cell death inducing agent, a protein phosphatase 2A activation enhancing agent, a protein tyrosine phosphatase 1B activation enhancing...
9770442 Self-assembling amphiphilic polymers as anti-cancer agents  
The invention provides amphiphilic biocompatible copolymers which have a hydrophilic backbone and pendant hydrophobic groups. The polymers form nanoscale molecular aggregates in aqueous...
9770414 Sustained release formulation of methotrexate as a disease-modifying antirheumatic drug (DMARD) and an anti-cancer agent  
Disclosed is are formulations comprising a multivesicular liposome and MTX, the administration of which results in a Cmax of MTX between 5% and 50% of the Cmax of an immediate release dosage form...
9770175 Apparatus and method for detecting a presence of cancer  
A method of examining breasts of a patient in an examination room to detect for potential breast cancer includes sliding a camera assembly along a rail between a pair of rail ends on a horizontal...
9766245 Method of detecting cancer based on glycan biomarkers  
The present invention provides a method for labeling or detecting a protein with certain glycosyl groups. The methods are particularly useful for detecting cancer cells comprising the detected...
9766244 Diagnosis and monitoring treatment of prostate cancer  
Provided herein are assays and methods related to determining a ratio of expression levels of PSA/PSMA or determining the expression level of PSMA in circulating tumor cells for diagnosis and/or...
9765401 Frizzled 2 as a target for therapeutic antibodies in the treatment of cancer  
Disclosed herein are methods of treating cancer in a subject, and methods for inhibiting growth, migration and/or invasion of a cancer cell in the subject, comprising administering to the subject...
9765337 Phosphoribosyl pyrophosphate synthetase 2 (PRPS2) as a therapeutic target in cancer treatment  
The present invention provides methods of selectively killing a cell, comprising contacting the cell with an agent that inhibits phospho-ribosyl pyrophophosphate synthetase 2 (PRPS2). The present...
9765334 Compositions and methods for prognosis of gastric cancer  
Described herein are compositions and methods for survival prediction in gastric cancer patients after surgical operation. The compositions are microRNA molecules associated with the prognosis of...
9765187 MRI contrasting agent for contrasting cancer cell  
The present invention relates to MRI contrasting agent for contrasting cancer cell which contains ultrafine nanoparticles. More particularly, the present invention is directed to a self-assembled...
9765147 Anti-CSFR1 antibody and anti PD-1 antibody combination therapy for cancer  
Methods of treating cancer with antibodies that bind colony stimulating factor 1 receptor (CSF1R) in combination with PD-1/PD-L1 inhibitors are provided.
9765118 Pharmaceutical composition for cancer prevention and treatment containing peptide originated from C12orf59 protein as an active ingredient  
As explained hereinbefore, the C12orf59 gene of the present invention suppresses cancer cell invasion and inhibits cancer cell survivability, and the over expression of C12orf59 protein or a...
9765117 Peptides for treating cancer  
Provided are novel peptides having a human minute binding protein-2 (HDM-2) targeting sequence that target the human minute binding protein-2. Also provided are fusion proteins comprising an HDM-2...
9765114 Method for cancer immunotherapy  
A novel compound of the formula (1): wherein X is a tyrosine residue or a methionine residue; Y and Z each are a single bond or the like; R1 is a hydrogen atom or the like; R2 is a hydroxy group...
9765113 Methods and agents for the treatment of cancer  
There are disclosed methods for prophylaxis or treatment of cancer in a mammal. The methods comprise administering an effective amount of an agent to the mammal, which binds to a MAP kinase or an...
9765061 Trail enhancers for the selective killing of cancer cells  
The invention is directed to methods of inducing apoptosis, arresting cell cycle, or inhibiting cellular proliferation, or any combination thereof, in a tumor cell, by administration of an...