Match Document Document Title
10471030 Immunomodulatory and differentiating function selective retinoid and rexinoid compounds in combination with immune modulators for cancer immunotherapy  
Disclosed herein are methods for treating cancer comprising administering CAR-modified immune cells and at least one Retinoic Acid Receptor and/or Retinoid X Receptor active agent.
10467755 Methods of cancer detection  
The present invention provides, among other things, methods of identifying cancerous or pre-cancerous tissue including providing a first region of tissue from a subject, calculating a roughness...
10467523 Methods and systems for predicting DNA accessibility in the pan-cancer genome  
Techniques are provided for predicting DNA accessibility. DNase-seq data files and RNA-seq data files for a plurality of cell types are paired by assigning DNase-seq data files to RNA-seq data...
10465251 lincRNA for the detection of esophageal cancer  
A method of analyzing tissue in a subject having or suspected of having cancer includes obtaining an expression profile from a sample of tissue obtained from the subject, wherein the expression...
10465250 Method for determining the survival prognosis of a patient suffering from pancreatic cancer  
The present invention relates to pancreatic cancer, and more particularly to the survival prognosis of a patient suffering from pancreatic cancer. The invention also aims to determine the...
10465004 Frizzled receptor antibodies for treatment of cancer  
The invention provides antibodies or an antigen-binding portion thereof, which recognize the human Frizzled 7 receptor. Further, the invention provides methods of using these antibodies for the...
10464990 Peptides, combination of peptides as targets and for use in immunotherapy against gallbladder cancer and cholangiocarcinoma and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10464978 Peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10464897 Compounds and methods for treating cancer  
The present application relates to compounds comprising an ester, a thioester, or a hydrazide moiety and methods of synthesizing these compounds. The present application also relates to...
10463743 Amphiphilic drug-drug conjugates for cancer therapy, compositions and methods of preparation and uses thereof  
The invention provides novel amphiphilic drug-drug conjugates useful as cancer therapeutics, and compositions and methods thereof.
10463734 Nanoparticle therapy in cancer  
Nanoparticles comprising a metal oxide and a platinum cluster having a height to base ratio greater than 1 and compositions containing the same are disclosed. Methods of using the nanoparticles in...
10463726 Method of inhibiting cancer in a mammal by administering an antibody to PTHrP  
The present disclosure is directed to a method for treating cancer in a mammal by administering a PTHrP inhibitor to the mammal to inhibit expression of the PTHrP1-173 isoform of PTHrP in the...
10463724 Breast cancer vaccine  
Compositions and methods for immunization against human breast cancer are disclosed. A breast cancer vaccine comprises an immunogenic polypeptide comprising human α-lactalbumin.
10463696 Peptides and combination of peptides for use in immunotherapy against epithelial ovarian cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10463695 Methods and compositions for use in the prevention, treatment and/or alleviation of cancer  
The ratio of zinc and cadmium is of significance for error-free proliferation and differentiation of cells. An understanding of the role of cadmium in the etiology of cancer offers possibilities...
10463686 Immune modulation with TLR9 agonists for cancer treatment  
The present invention relates to methods for treating a tumor, including a metastatic tumor, with TLR9 agonist in combination with an immune checkpoint inhibitor therapy.
10463671 Combination therapy for treating cancer  
The present invention relates to compositions comprising inhibitors of human histone methyltransferase EZH2 and one or more other therapeutic agents, particularly anticancer agents such as...
10463670 Use of non-peptide NK1 antagonists in a predetermined dose for the treatment of cancer  
Use of the non-peptide NK1 receptor antagonist, preferably Aprepitant, for the treatment of cancer in predetermined doses. The present invention also describes pharmaceutical compositions...
10463669 Composition for treating or preventing liver cancer  
The present application relates to a pharmaceutical composition containing compound 5-fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]-4-3H )-quinazolinone, and a pharmaceutically acceptable...
10463662 Non-platinum-based anti-cancer compounds for use in targeted chemotherapy  
Disclosed herein are non-platinum-based (NPB) anti-cancer compounds useful for targeted chemotherapy, e.g., to generate anti-cancer effects for the treatment of cancer and other disorders while...
10463654 Combination therapies for treating cancer  
Provided are methods for treating cancer in a patient by administering at least one antibiotic selected from the group consisting of clofazimine, rifabutin and clarithromycin, in combination with...
10463298 Device, method and system for implementing a physical area network for cancer immunotherapy  
A physical area network described herein enables significantly improved health monitoring and treatment by utilizing internal (in-body) mechanisms and information and external mechanisms and...
10463229 Endoscopic observation method and composition for improving diagnostic performance involving applying useful white opaque substance to diagnosis of gastric epithelial tumors (adenoma or gastric cancer)  
To develop a clinically useful composition and an endoscopic observation method that utilizes WOS properties. The composition for improving diagnostic performance, containing lipids as a component...
10458911 Method for searching candidate material for anti-cancer drug using localized surface plasmon resonance  
A method for screening an anticancer candidate is disclosed. The method includes immobilizing gold nanoparticles onto a substrate; binding a protein involved in carcinogenesis and metastasis to...
10458895 Predicting response to pemetrexed chemotherapy in non-small cell lung cancer (NSCLC) with baseline computed tomography (CT) shape and texture features  
Methods, apparatus, and other embodiments predict response to pemetrexed based chemotherapy. One example apparatus includes an image acquisition circuit that acquires a radiological image of a...
10457993 Biomarker RNF6 for colorectal cancer  
The present invention provides a method for diagnosing of colorectal cancer in a subject and a method for determining risk of recurrence of colorectal cancer among colorectal cancer patients by...
10457992 Hypermethylation biomarkers associated with poor survival outcomes for head and neck squamous cell cancer  
In accordance with one or more embodiments, the inventors have conducted the first comprehensive integrated genomic and epigenomic analysis in HNSCC, focusing on identifying genes that have...
10457947 Targeting of human glucocorticoid receptor beta in cancer  
A peptide nucleic acid (PNA) referred to herein as Sweet-P, compositions comprising the methods of making the same, mid methods of using the same, are described.
10457946 Methods for overcoming glucocorticoid resistance and for determining glucocorticoid resistance potential in cancer  
The invention provides methods for overcoming glucocorticoid resistance of cancers by inhibition of CASP1. Also disclosed are diagnostic methods for determining glucocorticoid resistance potential...
10457943 Antisense oligonucleotides for treatment of cancer stem cells  
The invention provides oligonucleotides complementary to a non-coding chimeric mitochondrial RNA as well as compositions and kits comprising the same, and their use in treating and preventing...
10457938 TTV miRNA sequences as an early marker for the future development of cancer and as a target for cancer treatment and prevention  
Described are TTV miRNAs and probes and primers comprising part of said TTV miRNA polynucleic acid. The use of said compounds for diagnosis of cancer or predisposition of cancer is also described.
10457740 Methods and compositions for treating cancer using P2RX2 inhibitors  
The present invention provides methods for treating cancer using P2RX2 inhibitors, such as P2RX2 inhibitory antibodies, among others. The invention also features compositions containing P2RX2...
10457734 IGF-1R antibody and its use for the diagnosis of cancer  
The present disclosure relates to a novel antibody, in particular a monoclonal antibody, capable of binding to IGF-1R, as well as the amino and nucleic acid sequences coding for said antibody.
10457729 Compositions and methods for treating cancer  
The invention provides compositions and methods for treating ovarian cancer. Specifically, the invention relates to administering a genetically modified T cell having α-folate receptor (FRα)...
10457725 Methods of treating skin cancer by administering a PD-1 inhibitor  
The present invention provides methods for treating, reducing the severity, or inhibiting the growth of cancer (e.g., skin cancer). The methods of the present invention comprise administering to a...
10457718 Compounds for the treatment of cancer  
The technology provided herein relates to novel isolated polypeptides and peptides having a growth inhibitory effect on human cancer cells. Nucleic acid molecules encoding said...
10457679 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer  
The specification generally relates to compounds of Formula (I): and pharmaceutically acceptable salts thereof, where R1, R2, R3, R4 and R5 have any of the meanings defined herein. The...
10457676 Capsazepine analogs for the treatment of cancer and other proliferative diseases  
The present disclosure relates generally to derivatives of capsazepine and methods of use thereof In some aspects, the present disclosure relates to using capsazepine derivatives to treat cancer...
10457662 Substituted amides for treating and preventing cancer  
This invention is in the field of medicinal chemistry. In particular, the invention relates to novel small molecule compounds having a quinolin-8-yl-nicotinamide structure (e.g., a compound having...
10457642 211-astatine containing radiotherapeutics for the treatment of cancer  
Described herein is an alpha-emitting radionuclide, 211At, which has been incorporated into a selective sigma-2 ligand moiety to provide cytotoxic capabilities to a chemical compound. As described...
10457639 Fluorescent regulators of RASSF1A expression and human cancer cell proliferation  
The invention provides methods for the treatment of cancer in a subject comprising administering a dansyl-carbazole compound.
10456469 Glutamine-high Z element compounds for treating cancer  
The present invention is a glutamine compound having a non-radioisotope high Z element attached via a linker, which enters the mitochondrion and is subsequently exposed to ionizing radiation. When...
10456420 Genetically modified NK-92 cells and monoclonal antibodies for the treatment of cancer  
This invention is directed to treatment of a subject having or suspected of having a cancer comprising administering to the subject a monoclonal antibody and NK-92 expressing Fc receptor.
10456407 Combination therapy for treating cancer  
The present disclosure relates to compositions comprising inhibitors of human histone methyltransferase EZH2 and one or more other therapeutic agents (such as tyrosine kinase inhibitors or...
10456399 Method for treating cancer patients with severe renal impairment  
A method for treating cancer in patients with creatinine clearance of 15 mL/min or more and less than 30 mL/min, including dividing a combination drug containing α,α,α-trifluorothymidine (FTD) and...
10456388 Antihistamine for use in treatment of breast cancer  
Disclosed herein is desloratadine or ebastin for use in treatment of a patient diagnosed with breast cancer. Also disclosed is desloratadine or ebastin for use in treatment of a patient diagnosed...
D864395 Cover for cancer cell observation camera  
10452970 Methods and systems of evaluating a risk of a gastrointestinal cancer  
A method of evaluating gastrointestinal cancer risk. The method comprises generating a set of features comprising a plurality of current blood test results from a blood collected from a target...
10451626 Method for detecting a solid tumor cancer  
A method for indicating a presence or non-presence of a predefined solid tumor cancer in an individual, comprising the steps of: A. Providing at least one biological sample originating from said...
10451625 Methods of detecting cancer  
Method and kits for detecting cancer, and in particular breast cancer, in a subject by measuring the levels of at least one of a series of biomarkers, as compared to a control sample lacking...