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9545417 Methods of inhibiting cancer stem cells with HMGA1 inhibitors  
The presently disclosed subject matter relates to methods of inhibiting cancer stem cells and growth of aggressive and/or poorly differentiated metastatic tumors comprising the cancer stem cells...
9540697 Prostate cancer markers  
The invention relates to the identification and selection of novel genomic regions (biomarker) and the identification and selection of novel genomic region combinations which are hypermethylated...
9540695 Compositions and methods for prognosis of ovarian cancer  
Described herein are compositions and methods for the prediction of the prognosis of ovarian cancer subjects. The present invention further provides methods for distinguishing between histological...
9540647 Methods and compositions for the treatment of cancer  
Some embodiments of the present invention relate to methods and compositions for treating cancer. More embodiments include methods and compositions for modulating the activity of the Hedgehog pathway.
9540641 Cancer treatment  
In certain embodiments, methods, compounds, and compositions for treating B-cell lymphoma or hepatocellular carcinoma by inhibiting expression of STAT3 mRNA or protein in an animal are provided...
9540619 MELK regulation for the treatment of breast cancer  
Methods for inhibiting growth or proliferation of breast cancer cells are provided. The methods include administering to a subject in need thereof in an amount that is effective to inhibit growth...
9540614 Method for generating cancer stem cells from immortalized cell lines  
A method is described for generating a novel cancer stem cell line that possesses characteristics associated with stem cells, by co-culturing a human immortalized cell line and bone marrow-derived...
9540450 Methods and antibodies for treating cancer  
The invention relates to novel methods for the treatment of tumors, comprising administration of a bispecific antibody or a combination of two or more non-cross-blocking antibodies that recognize...
9540445 Compositions and methods for treatment of cancer  
The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the...
9539340 Bladder cancer specific ligand peptides  
The present invention is directed to bladder cancer specific ligand peptides, comprising the amino acid sequence X1DGRX5GF (SEQ ID NO:1), and methods of their use, e.g., for imaging detection for...
9539327 Small molecule cancer treatments that cause necrosis in cancer cells but do not affect normal cells  
A method of treating cancer in a subject, including: providing a subject having a plurality of cancer cells; and administering to the subject, a therapeutically effective amount of a composition...
9539325 Combination therapy for treating breast cancer  
The invention provides compositions and methods for treating breast cancer. Specifically, the invention relates to administering a Transforming Growth Factor beta (TGFβ) antagonist in combination...
9539323 Methods and compositions for malic enzyme 2 (ME2) as a target for cancer therapy  
The present invention relates to methods, compositions, and diagnostic tests for treating and diagnosing cancer and other related diseases that result in dysregulation of malic enzyme 2. In...
9539290 Individualized bacterial treatment of pancreatic cancer  
An individualized bacterial treatment of cancer is provided. The treatment includes a strain of bacteria modified by in-vivo passage through tumor grafts in experimental animals, where the...
9539272 HDAC 6 inhibitor-based methods for treating cancer  
This invention provides methods for treating a subject afflicted with cancer, comprising concurrently administering (i) an HDAC 6-selective inhibitor and (ii) a suitable cytotoxic agent such as...
9539258 Quinazoline derivatives for the treatment of cancer diseases  
The present invention relates to the use of quinazolines of formula (I), wherein the groups Ra to Rd have the meanings given in the claims and specification, in cancer therapy.
9539257 Method of treating cancer  
Methods are provided of treating a human for cancer comprising administering at least one dose of lapatinib, or a pharmaceutically acceptable salt or composition thereof, to a patient, wherein...
9539254 Mutant ROS expression in human cancer  
The invention provides the identification of the presence of mutant ROS protein in human cancer. In some embodiments, the mutant ROS are FIG-ROS fusion proteins comprising part of the FIG protein...
9539237 Compositions and methods for drug-sensitization or inhibition of a cancer cell  
The disclosure provides rifamycin and rifamycin derivative compositions, including rifabutin and rifabutin derivative compositions able to cause drug-sensitization in a cancer cell or inhibition...
9539236 Pharmaceutical composition for preventing or treating cancer  
Exemplary embodiments relate to a novel anticancer composition including a compound represented by chemical formula 1 or pharmaceutically acceptable salt thereof as an active ingredient:
9539231 Method for treating triple-negative breast cancer using AMPI-109  
A targeted approach toward the treatment of TN breast cancer by using AMPI-109 is disclosed. AMPI-109 is a compound with remarkable “cancer-specific” characteristics. In particular, AMPI-109...
9539225 Anemia of cancer improving/prophylactic agent  
A method for ameliorating and/or preventing cancerous anemia includes administering to a subject in need thereof an agent containing 5-aminolevulinic acid (ALA) or a derivative thereof, or a salt...
9535069 Method of measuring cancer related substances by raman spectroscopy  
A method for measuring cancer related substances including cancer cell-derived free DNA by Raman spectroscopy, involving steps for preparing a biochip having a meso-crystal region of silver oxides...
9535068 Oral cancer point of care diagnostics  
A point of care diagnostic test, device and disposables for determining a patient risk for oral cancer in the same visit that a sample is collected.
9534999 Nanostructured biomimetic device for detecting a cancer cell or cancer cells  
The present invention provides a single cancer direct detection device comprises an electrode having a nanopore biomimetic membrane inducing a bio-communication signal by cancer cells selectively...
9534258 Devices and methods for prognosis prediction for melanoma cancer  
The invention relates to prognostic markers and prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for melanoma. Specifically,...
9534256 Methods and compositions for correlating genetic markers with risk of aggressive prostate cancer  
The present invention provides a method of identifying a subject as having an increased risk of having or developing aggressive prostate cancer, comprising detecting in the subject the presence of...
9534254 Patient stratification for cancer therapy based on genomic DNA microarray analysis  
The method of the invention comprises the stratification of a cancer patient population into various cancer therapy groups based on analysis by genomic DNA microarray of multiple gene...
9534249 Predicting cancer outcome  
This document provides methods and materials related to assessing prostate cancer in mammals. For example, this document provides nucleic acids and polypeptides that can be analyzed to determine...
9534248 Tumor-specific minicircles for cancer screening  
The present disclosure encompasses embodiments of nucleic acid minicircle vectors most advantageous for the detection of tumor cells. In particular, the minicircles of the disclosure incorporate a...
9533978 Pyrimidine derivatives and their use in the treatment of cancer and further diseases  
The invention concerns compounds of Formula (I): wherein L1, R1, R2, R3, R4 and X are as defined in the description. The present invention also relates to processes for the preparation of such...
9533054 Amphiphilic drug-drug conjugates for cancer therapy, compositions and methods of preparation and uses thereof  
The invention provides novel amphiphilic drug-drug conjugates useful as cancer therapeutics, and compositions and methods thereof.
9532984 Therapeutic combination for cancer treatment  
This invention relates to a synergistic pharmaceutical combination of glucose lowering drugs and autophagy inhibitors, kits containing such combinations, and methods of using such combinations to...
9532972 Increasing taxane sensitivity in cancer cells  
Disclosed herein are combinatorial therapies for treating or preventing reoccurrence of cancer. The therapies involve inhibition of LIMK1 in conjunction with taxane therapy. Specifically...
9532960 Pharmaceutical composition and kit for applying metformin and sodium butyrate in Kras mutation cancer treatment  
A method for using metformin and sodium butyrate in combination to treat a cancer patient with K-ras mutation is disclosed. When administering the pharmaceutical composition to a cancer patient,...
9532765 Ultrasound scanning assistance apparatus for breast cancer diagnosis and method of ultrasound scanning  
An ultrasound scanning assistance apparatus for diagnosis of a breast cancer is provided. The ultrasound scanning assistance apparatus includes a fixing container including a scan surface to scan...
9528991 Individualized cancer therapy  
In certain embodiments, the invention provides methods for treating cancer, comprising: obtaining a specimen of cancer tissue and normal tissue from a patient; extracting total protein; obtaining...
9528982 Bad phosphorylation determines ovarian cancer chemo-sensitivity and patient survival  
Despite initial sensitivity BAD-protein phosphorylation were evaluated in patient samples and cell lines as determinants of chemo-sensitivity and/or clinical outcome, and as therapeutic targets....
9527922 Humanized alpha-enolase specific antibodies and methods of uses in cancer therapy  
A humanized antibody, or a binding fragment thereof, wherein the humanized antibody binds human ENO1 (GenBank: AAH50642.1), wherein the antibody comprises a light chain variable region (VL) domain...
9527919 High affinity anti-prostate stem cell antigen (PSCA) antibodies for cancer targeting and detection  
The present invention provides novel high affinity antibodies and fragments thereof that bind to the cancer antigen PSCA. The antibodies of the present invention may be used for cancer diagnosis,...
9527895 CAPCNA peptide therapeutics for cancer  
Administration of compositions comprising cell-permeable cancer-specific proliferating cell nuclear antigen derived peptides and their variants reduces the proliferation of cancer cells and also...
9526911 Immune mediated cancer cell destruction, systems and methods  
Systems and methods for delivering electric fields to a target tissue of a patient for destruction of cancerous cells so as to elicit or induce a specific anti-cancerous cell immune response in...
9526800 Cancer-related extracellular matrix signatures and related methods and products  
Proteomic methods for identifying cancer related proteins and related products and kits are provided. The cancer specific proteins are extracellular matrix proteins that are associated with...
9526779 Method for cancer immunotherapy and pharmaceutical compositions based on oncolytic non-pathogenic Sendai virus  
The invention relates to the field of immunology and medicine, more specifically, oncology, and can be useful for the treatment of patients with carcinomas and sarcomas. A pharmaceutical...
9526768 Compositions for the treatment of cancer  
The present invention relates to novel compositions comprising proteolytic enzymes and fining agents as well as methods for the treatment and/or prevention of cancer using these compositions.
9526759 Activin-actriia antagonists and uses for treating or preventing breast cancer  
In certain aspects, the present invention provides compositions and methods for treating or preventing breast cancer in humans.
9526709 Compositions and methods for treating cancer  
The present invention provides, in part, compositions and methods for treating cancer using a combination of C6-ceramide and other anti-cancer agents.
9523691 Use of the olfactomedin-4 protein (OLFM4) in colorectal cancer diagnosis  
The present invention provides a method for diagnosing KRAS mutations in colorectal cancers by measuring the level of OLFM4. In another aspect, the present invention relates a method of predicting...
9523689 Treating bladder cancer patients and identifying bladder cancer patients responsive to treatment  
This documents provided methods and materials involved in treating bladder cancer. This document also provides methods and materials involved in identifying bladder cancer patients likely or...
9523688 Diagnosis method and treatment for cancer using liv21 proteins and E2F1/E2F4 biomarkers  
The invention concerns a novel diagnostic and/or prognostic test for cancer. More particularly, the invention concerns the human LIV21 protein, its use as cancer diagnostic and prognostic markers....