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9222089 Aging marker, method for evaluating aging inhibitor, and cancer inhibitor  
The present invention aims to elucidate a miRNA involved in cellular senescence and to provide a method of use thereof. The senescence marker of the present invention comprises a gene transcript...
9222086 Compositions and methods for silencing genes expressed in cancer  
The present invention provides therapeutic nucleic acids such as interfering RNA (e.g., siRNA) that target the expression of genes associated with tumorigenesis and/or cell transformation, lipid...
9221872 Peptides and peptidomimetics in combination uses and treatments for cancer patient subpopulations  
This invention provides compounds including peptides and peptidomimetics that can be used to treat cell proliferative disorders, such as those associated with benign and malignant tumor cells....
9221866 Phosphoramidate derivatives of 5-fluoro-2′-deoxyuridine for use in the treatment of cancer  
Phosphoramidate derivatives of 5-fluoro-2′-deoxyuridine are disclosed for use in the treatment of cancer, especially in the treatment of cancer where the patient shows resistance, for example, in...
9221817 Anti-cancer compound and pharmaceutical composition containing the same  
The invention relates to a compound of formula (I), more specifically in the levorotatory form (1a) thereof, in particular the form having a rotatory power [α]D=−38.6+0.7 at a concentration of...
9221799 Anti-cancer agents  
The present invention provides a compound of Formula (I), or a pharmaceutical acceptable derivative, salt or prodrug thereof. Further provided is a method of treatment of cancer in a subject...
9220793 Methods for in vivo identification of cancer initiating cells by multimodality reporter gene imaging  
The present invention relates to a method for detecting cancer initiating cells in living animal body by multimodality reporter gene imaging. In the method of this invention, cells escaping from...
9220774 Methods of treating cancer by administering anti-GPR49 antibodies  
Described herein are antibodies against GPR49 and uses of such antibodies. Various aspects relate to monoclonal, humanized, or fully human antibodies against GPR49, hybridomas or other cell lines...
9220771 Peptide for use in the treatment of breast cancer and/or bone metastases  
The invention relates to the use of the Peptide of the formula Cyclo-(Arg-Gly-Asp-DPhe-NMe-Val) and/or the pharmaceutically acceptable derivatives, solvates and/or salts thereof, for the...
9220763 Nano-vehicle derived from tumor tissue, and cancer vaccine using same  
The present invention relates to a cancer vaccine, and specifically, to a pharmaceutical composition for treating cancer containing a nano-vehicle derived from tumor tissue, and a method for...
9220723 Cancer therapy  
The present invention provides agents useful in the treatment of cancer, as well as systems for identifying and/or characterizing such agents, and systems for identifying and/or characterizing...
9220714 Nitrofuran compounds for the treatment of cancer and angiogenesis  
The invention is directed to the synthesis and use of nitrofuran compounds, especially Nifurtimox, as medicaments to treat cancer, especially neuroblastoma, and to inhibit angiogenesis. The...
9220705 Method of treating colorectal cancer  
The present invention relates to the use of certain platinum compounds including [PtCl2(cis-1,4-diaminocyclohexane)], or combinations of these compounds with a variety of other agents for treating...
9220695 Polyenolic zinc-binding agents (pezbins) actively promote inactivation of cancer stem cells and potentiate cytotoxic anti-tumor drug substances  
The present invention provides a method of inhibiting the growth of or promoting differentiation and destruction of cancer stem cells (CSCs) comprising contacting the cancer stem cells with a...
9217741 Bioactive compounds from phytoplankton containing glycosidic residue for apoptosis and cancer treatment  
Phytoplankton represent a potential source of bioactive compounds. The present disclosure provides, inter alia, methods for identifying glycerolipids and apoptosis-inducing sphingosine-like lipids...
9217149 Pharmaceutical composition for treating cancer  
The present invention provides a pharmaceutical composition for treating cancer, comprising at least one selected from deoxyribonucleic acids (DNA) for encoding small interfering RNA (siRNA) which...
9217032 Methods for treating colorectal cancer  
The present disclosure is directed to methods of treating and preventing colorectal cancer metastasis or recurrence of colorectal cancer with compositions comprising anti-progastrin antibodies.
9216980 Methods of use of diazacarbazoles for treating cancer  
Methods of use of compounds of formula (I) for treating cancer: wherein X, Y, X, R3, R5 and R6 are as defined herein.
9216218 Monoclonal antibodies for treatment of cancer  
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing GT468, including tumor-related diseases such as breast...
9216172 Method for determining effectiveness of cancer treatment by assessing the presence of a KIF5B-RET chimeric gene  
In order to identify a gene that can serve as an indicator for predicting the effectiveness of a drug treatment of cancer and to provide a novel method for predicting the effectiveness of a drug...
9216165 Combination of a statin and a taxane for the treatment of gastric cancer  
The present invention relates to a combination of (i) a statin, and (ii) a taxane, for simultaneous or sequential use in the treatment of a patient suffering from solid tumor, e.g. a gastric...
9213029 Method for diagnosing breast cancer by detection of polymeric immunoglobulin receptor in vesicles isolated from patients  
A composition for breast cancer diagnosis using a material specifically binding to a polymeric immunoglobulin receptor (PIGR) or a fragment thereof, and a method for detecting breast cancer or...
9212228 Monoclonal antibodies against claudin-18 for treatment of cancer  
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric...
9212221 Form-specific antibodies for NAG-1 (MIC-1, GDF-15), H6D and other TGF-β subfamily and heart disease and cancer diagnoses  
A method of producing form-specific anti-peptide antibodies for a wild type protein and its one amino acid mutated protein using a peptide antigen, by obtaining a protein sequence of the wild type...
9212138 Use of derivatives of indoles for the treatment of cancer  
The present invention relates to the use of derivatives of indoles having a general formula (I) as follow: for the manufacture of a pharmaceutical composition intended for the treatment of cancer.
9211333 Anti-cancer agents synthesized based on miliusane compounds  
The present invention is in the field of pharmaceuticals and chemical industries. In particular, the present invention relates to new anticancer agents based on miliusane compounds. The present...
9211322 Immunotherapeutical method for treating cancer  
Pharmaceutical compositions useful as vaccines are described containing a purified surface or excreted protein qualitatively or quantitatively associated with a type of cancer, at least one...
9211314 Treatment selection for lung cancer patients using mass spectrum of blood-based sample  
A test for predicting whether a non-small-cell lung cancer patient is more likely to benefit from an EGFR-I as compared to chemotherapy uses a computer-implemented classifier operating on a mass...
9211291 Treatment regimen utilizing neratinib for breast cancer  
An extended regimen for treatment of HER-2/neu overexpressed/amplified cancer is described, with involves delivering a course of neratinib therapy to HER-2/neu overexpressed/amplified cancer...
9207242 Cadherin-17 as diagnostic marker and therapeutic target for liver cancer  
Compositions and methods for diagnosing, treating and/or preventing cancers characterized by CDH17 overexpression based on the detection of CDH17 or the use of CDH17 as a target for therapeutic...
9207205 Method and apparatus for cancer screening  
A method and apparatus for detection of pteridine levels in a biological sample using CE-LIF which is useful for early cancer screening involving fully oxidizing pteridine compounds in a sample...
9206481 Prostate cancer-specific alterations in ERG gene expression and detection and treatment methods based on those alterations  
Alterations in ERG gene expression can be observed in patients with prostate cancer. Specific ERG isoforms are associated with, or involved in, prostate cancer. Compositions comprising these...
9206258 Anti-prostate cancer antibodies and methods of detection and treatment of prostate cancer using the same  
Disclosed herein are antibodies that detect a lipid-like antigen on prostate cancer cells and methods of detecting and treating prostate cancer using the same.
9206245 Immunogenic peptides and methods of use for treating and preventing cancer  
Disclosed are immunogenic peptides, related fusion proteins, nucleic acids encoding the peptides or fusion proteins, conjugates, expression vectors, host cells, and antibodies. Also, disclosed are...
9206236 Peptides for treating cancer  
The present invention relates to peptide from 4 to 50 amino acids comprising a phosphorylated pYX1X2X1 motif (SEQ ID NO: 1), wherein each X1 independently is M or Nle and X2 is any amino acid,...
9206192 Trolox derivative-modified fat-soluble anti-cancer pharmaceutical compounds, preparations, preparing methods and use thereof  
Disclosed is a trolox derivative-modified fat-soluble anti-cancer pharmaceutical compound having a structure as represented by formula I or II. An active moiety of the anti-cancer pharmaceutical...
9206165 Tetrazolo hydrazine derivatives and pharmaceutical composition comprising same as active ingredient for preventing or treating cancer  
Provided are novel tetrazolo hydrazone derivatives or pharmaceutically acceptable salts thereof. The derivatives and the salts may inhibit the proliferation of cancer cells in a low molar...
9206132 Use of a novel aminopyridine derivative to prevent or treat cancer  
An aminopyridine derivative of Formula 1 and a method of preventing or treating cancer using the same. Formula 1: In Formula 1: X1 and X2 are each independently selected from the group consisting...
9206124 Treatment of drug-resistant cancer with 2-aryl-2-(3-indolyl) acetohydroxamates  
A pharmaceutical composition, a method of producing same, and a method of providing cancer therapy therein comprising a pharmaceutically acceptable excipient or carrier and a compound Formula 3 as...
9205140 MSI-specific frameshift peptides (FSP) for prevention and treatment of cancer  
Described is a vaccine for prevention and treatment of cancer characterized by microsatellite instability (MSI). The vaccine contains an MSI-specific frameshift peptide (FSP) generating humoral...
9205102 Method for treatment of castration-resistant prostate cancer  
Castrate resistant prostate cancer cell lines exhibiting resistance to the androgen-receptor antagonist enzaluatamide overexpress one or both of IGFBP-2 or IGFBP-5 when compared to non-resistant...
9205101 Cancer treatment by combining DNA molecules mimicking double strand breaks with hyperthermia  
The present invention relates to a method for treating a cancer including a combination of a treatment by a nucleic acid molecule mimicking double strand breaks with hyperthermia.
9205098 Anti-cancer therapies  
Methods for the treatment of cancer are described. In particular, methods for treatment of cancer comprising administration of glufosfamide alone or in combination with another anticancer agent...
9205091 Diazeniumdiolated compounds, pharmaceutical compositions, and method of treating cancer  
Disclosed is a method of treating cancer in a patient comprising administering to the patient an effective amount of a diazeniumdiolated (N2O2-containing) compound or a pharmaceutically acceptable...
9205086 Cancer therapy using a combination of a Hsp90 inhibitory compounds and a EGFR inhibitor  
A pharmaceutical combination comprising an EGFR inhibitor and an Hsp90 inhibitor according to the following formulae (I) or (Ia) a tautomer, or a pharmaceutically acceptable salt thereof, wherein...
9201044 Compositions, methods and kits for diagnosis of lung cancer  
Methods are provided for identifying biomarker proteins that exhibit differential expression in subjects with a first lung condition versus healthy subjects or subjects with a second lung...
9200328 Methods and kits for diagnosing the prognosis of cancer patients  
The prognosis of a cancer patient can be determined by analyzing the modulation of expression of specified genes in the tumor tissue. Genes uniquely up-regulated in adult stem cells that can...
9200325 Diagnostic methods and kit for detecting cancer  
The present disclosure is directed to compositions and methods for detecting elevated microRNA U6 concentrations in serum relative to a standard microRNA (e.g. SNORD44) as a diagnostic indicator...
9200285 Clusterin antisense therapy for treatment of cancer  
A method for providing antisense therapy which reduces the expression of clusterin to provide therapeutic benefits in the treatment of cancer comprising administering from 40 to 640 mg...
9200280 Methods and compositions for the treatment of cancer or other diseases  
The present invention relates to methods and compositions for the treatment of diseases, including cancer, infectious diseases and autoimmune diseases. The present invention also relates to...