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8920789 Use of polymer D-lactic acid (PDLA) or equivalents thereof to inhibit growth of cancer cells and diagnose cancers  
The invention provides method for sequestering or trapping L-lactate in or near a tumor cell comprising contacting an isolated polymer of D-lactic acid (PDLA) or an equivalent, derivative or...
8920777 Toxins and radionuclides coupled to IGF-1 receptor ligands for treatment of cancer  
The invention provides an insulin-like growth factor-1 (IGF-1) receptor ligand carrying a therapeutic radionuclide for treatment of cancer is provided. A method of treating cancer using the IGF-1...
8916679 Peptides binding to the dimer interface of thymidylate synthase for the treatment of cancer  
Provided are peptides that bind to the thymidylate synthase protein, in particular to human thymidylate synthase (hTS) protein, for the treatment of cancer. Further provided are peptides that can...
8916605 Compounds and methods for treating cancer and viral infections  
The present application relates to the use of one or more compounds of Formula (I) or pharmaceutically acceptable solvates or prodrugs thereof, for treating cancer or for treating or preventing a...
8916571 Methods of treating cancer using inhibitors of 5′-methylthioadenosine phosphorylase  
The invention relates to the treatment of cancer using an inhibitor of 5′-methylthioadenosine phosphorylase (MTAP). The invention particularly relates to the treatment of prostate cancer and head...
8916541 Synergistic combination of honokiol and modified citrus pectin in cancer therapy  
The invention comprises the administration of an amount of honokiol (HNK) and Modified Citrus Pectin (MCP) or similar pectin or alginate in amounts synergistic to inhibit cancer. The inhibition...
8916530 Individualized cancer therapy  
In certain embodiments, the invention provides methods for treating cancer, comprising: (a) obtaining a specimen of cancer tissue and normal tissue from a patient; (b) extracting total protein and...
8916381 Methods for treatment of cancer  
The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the...
8916354 Bladder cancer diagnosis composition containing APE1/Ref-1 and bladder cancer diagnostic kit using same  
Provided are a bladder cancer diagnosis composition containing APE1/Ref-1, a bladder cancer diagnostic kit containing an antibody which specifically binds to the APE1/Ref-1, and a method of...
8916199 Inhibition of angiogenesis associated with ovarian cancer by nanoparticles of cerium oxide  
The invention provides a method of treating ovarian cancer in a mammal, the method inhibits angiogenesis associated with the cancer and comprises the parenteral administration to the mammal of an...
8915911 Device and method for destruction of cancer cells  
The present invention provides devices and systems, as well as methods, of electric field delivery and non-thermal or selective ablation of target tissue regions, including selective ablation of...
8914238 Method for predicting breast cancer patient response to endocrine therapy  
A mass-spectral method is disclosed for determining whether a breast cancer patient is likely to benefit from administration of a combination treatment in the form of a targeted anti-cancer drug...
8912311 Generation of a cancer-specific immune response toward MUC1 and cancer specific MUC1 antibodies  
The present invention provides a method for inducing a cancer specific immune response against MUC1 using an immunogenic glycopeptide. Other aspects of the invention are a pharmaceutical...
8912214 Use of Chk2 kinase inhibitors for cancer treatment  
Described herein are Chk2-inhibitor compounds and derivatives thereof, and methods of treating or preventing disease and disease symptoms using the compounds and compositions thereof.
8912171 Methods of use for 2,5-dihydroxybenzene sulfonic acid compounds for the treatment of cancer, rosacea and psoriasis  
The invention describes compositions and methods of use for 2,5-dihydroxybenzene sulfonic acid compounds and pharmaceutically acceptable salts thereof. The invention provides methods for (a)...
8912159 Analyzing semaphorin7a (Sema7A) levels for assessing cancer metastatic potential and methods of treatment  
Methods, assays, and kits for determining a cancer's (e.g., breast cancer) metastatic potential and tumor aggressiveness in a subject (e.g., a human patient) and for measuring a subject's response...
8912155 Method for analyzing secretome, biomarker for lung cancer metastasis, and siRNA compound for inhibiting lung cancer metastasis  
A method for analyzing secretome, a biomarker for lung cancer metastasis, and a siRNA compound for inhibiting lung cancer metastasis are disclosed. The method for analyzing secretome of the...
8911993 Compositions for treatment of cancer  
The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the...
8911940 Methods of assessing a risk of cancer progression  
Methods and kits that use miRNA expression to predict the development of brain metastases in non-small cell lung cancer patients are disclosed.
8911740 Pharmaceutical composition for treating and/or preventing cancer  
According to the present invention, a cancer antigen protein to be specifically expressed on the surfaces of cancer cells is identified and thus the use of an antibody targeting the cancer antigen...
8911736 Combination therapy for treating breast cancer  
The invention provides compositions and methods for treating breast cancer. Specifically, the invention relates to administering a Transforming Growth Factor beta (TGFβ) antagonist in combination...
8911725 Co-targeting of aurora A kinase and LIM kinase 1 for cancer therapy  
Disclosed herein are therapies for treating or preventing reoccurrence of cancer. The therapies involved inhibition of LIMK1 in conjunction with AurKA inhibition. Specifically exemplified herein...
8906932 Methods of treating cancer using 3-(5-amino-2-methyl-4-oxo-4Hquinazolin-3-yl)-piperidine-2,6-dione  
Provided herein are methods of treating, preventing and/or managing cancers, which comprise administering to a patient 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6 -dione, or an...
8906896 Platinum acridine anti-cancer compounds and methods thereof  
Acridine containing cisplatin compounds are disclosed that show greater efficacy than other cisplatin compounds for treating cancer. The compounds are compounds of Formula I wherein the variables...
8906885 Treating cancer with HSP90 inhibitory compounds  
Methods of treating cancer with a compound of formulae (I) or (1a) are disclosed. Also provided are methods of treating a cancer with a mutation in ALK or a c-MET mutation with a compound of...
8906879 Combination for the treatment of cancer  
The present invention relates to a method of treating cancer in a human and to pharmaceutical combinations useful in such treatment. In particular, the method relates to a cancer treatment method...
8906869 Effective treatment of ovarian cancer using triciribine and related compounds  
The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat ovarian cancer by one or a combination of (i) administering triciribine only...
8906682 Methods for treatment of cancer  
The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the...
8906631 Method for identifying, expanding and removing adult stem cells and cancer stem cells  
Described are the use of stem cell markers for the isolation of stem cells and the use of the obtained stem cells in, for example, research or treatment, such as for the preparation of a...
8906606 Method of predicting and reducing risk of metastasis of breast cancer to lung  
A signature for breast cancer tissue derived from a patient is established that is indicative of the virulence and risk of lung metastasis by determining the expression levels to define a sample...
8906422 Method for inhibiting cancer using arsenic trioxide  
The invention provides a method for treating cancers that are dependent on cyclin D1 for proliferation, survival, metastasis and differentiation, involving administering a composition containing...
8906376 Drug conjugates and their use for treating cancer, an autoimmune disease or an infectious disease  
Drug-Linker-Ligand Conjugates are disclosed in which a Drug is linked to a Ligand via a peptide-based Linker unit. In one embodiment, the Ligand is an Antibody. Drug-Linker compounds and Drug...
8906342 Compositions against cancer antigen LIV-1 and uses thereof  
Described herein are methods and compositions that can be used for diagnosis and treatment of cancer.
8901509 Multi-axis charged particle cancer therapy method and apparatus  
The invention comprises a multi-axis charged particle irradiation method and apparatus. The multi-axis controls includes separate or independent control of one or more of horizontal position,...
8901306 Methods and compositions useful in treating cancer and reducing Wnt mediated effects in a cell  
Provided herein are novel compounds, pharmaceutical compositions for use, inter alia, in methods of reducing Wnt-mediated effects and treating cancer.
8901175 Use of opioids or opioid mimetics for the treatment of resistant cancer patients  
The use of opioids or opioid mimetics is suggested for the manufacture of a medicament for the treatment of resistant cancer patients.
8901171 Compounds for suppressing a peripheral nerve disorder induced by an anti-cancer agent  
The present invention provides a medicament that suppresses (or mitigates) various neurological symptoms caused by a peripheral nerve disorder induced by an anti-cancer agent.
8901137 Methods of treating cancer using pyridopyrimidinone inhibitors of PI3K and mTOR in combination with autophagy inhibitors  
The invention provides compounds of Formula I: that inhibit the PI3Ks and mTOR that are useful in the treatment of cancer in humans when used in combination with autophagy inhibitors.
8901096 Method for identifying compounds for cancer therapy  
The present invention relates to an in vitro method for identifying and evaluating compounds useful in the treatment of different types of cancer, especially lung, breast, colorectal and bladder...
8901093 Custom vectors for treating and preventing pancreatic cancer  
The present invention is directed to a system for treating individuals at risk of developing or suffering from pancreatic cancer. The system comprises administering to the individual a recombinant...
8901082 Immunity-inducing agent and method for detection of cancer  
An immunity-inducing agent comprising as an effective ingredient(s) at least one polypeptide selected from the following polypeptides, the polypeptide(s) having an immunity-inducing...
8901075 Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders  
The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a...
8900819 ADRB2 cancer markers  
The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to...
8900813 CIP2A as a biomarker in detection of cervical cancer  
The present invention provides methods and compositions for detecting cervical cancer in a human. The present invention provides CIP2A as a biomarker detectable in a biological sample from cervix...
8900588 Methods for treating breast cancer  
The present disclosure is directed to methods of treating and preventing breast cancer or recurrence of breast cancer with compositions comprising anti-progastrin antibodies.
8896239 Charged particle beam injection method and apparatus used in conjunction with a charged particle cancer therapy system  
The invention comprises a charged particle beam injection method and apparatus used in conjunction with multi-axis charged particle radiation therapy of cancerous tumors. The negative ion beam...
8895746 Compounds that suppress cancer cells and exhibit antitumor activity  
The present invention provides compounds S3I-201.1066 (Formula 1) and S3I-201.2096 (Formula 2) as selective Stat3 binding agents that block Stat3 association with cognate receptor pTyr motifs,...
8895719 Markers for pre-cancer and cancer cells and the method to interfere with cell proliferation therein  
A novel family of human mitochondrial RNAs, referred to as chimeric RNAs, which are differentially expressed in normal, pre-cancer and cancer cells, are described. Oligonucleotides targeted to the...
8895611 Cytotoxic compounds for treating cancer  
The cytotoxic compounds are gold(III) complexes of the type [(diaminocyclohexane)AuCl2]Cl, derived from sodium tetrachloroaurate(III) dihydrate NaAuCl4.2H2O. Specifically, the cytotoxic compounds...
8895605 Pyrrolidine-substituted flavones as radio-sensitizers for use in the treatment of cancer  
The present invention relates to a combination for the treatment of cancer wherein the combination exhibits a synergistic effect. The combination comprises radiation and at least one cyclin...