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9877978 Compositions comprising NDGA derivatives and sorafenib and their use in treatment of cancer  
The present invention provides pharmaceutical compositions comprising derivatives of NDGA, including M4N (tetra-O-methyl nordihydroguaiaretic acid) and sorafenib and their use in the inhibition...
9877962 Piperazinyl derivatives for the treatment of cancer  
Piperazinyl derivatives of formula (I) and their use as a drug, particularly for the treatment of cancer, are disclosed. Also disclosed are pharmaceutical compositions comprising the piperazinyl...
9877958 Apoptosis-induced agents for the treatment of cancer and immune and autoimmune diseases  
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed...
9877944 Use of a composition comprising fish oil and juice for the treatment and/or post treatment of cancer  
Disclosed is a composition including a fish oil and a juice in an oil-in-water emulsion for use in treatment and post-treatment of cancer.
9873916 Method for predicting response to trastuzumab therapy in breast cancer patients  
This invention relates to a composition and a method for prediction of a response to Trastuzumab therapy in a breast cancer patient, and more specifically, a composition, a kit, a DNA chip, and a...
9873915 Grading, staging and prognosing cancer using osteopontin-C  
The present disclosure provides methods and kits that can be used to determine the grade or stage of a breast or other cancer, such as a ductal carcinoma in situ (DCIS). By determining the grade,...
9873878 Compositions and methods for use in treating silicosis and lung cancer  
A method for treating an inflammatory disease is provided. The method comprises administering an effective amount of a BLT1 inhibitor to a subject in need thereof. The BLT1 inhibitor is selected...
9873876 Cancer treatment  
In certain embodiments, methods, compounds, and compositions for treating B-cell lymphoma or hepatocellular carcinoma by inhibiting expression of ST AT3 mRNA or protein in an animal are provided...
9873747 Fusion proteins that facilitate cancer cell destruction  
Provided is a fusion protein comprising a polypeptide component that blocks binding of CD47 to SIRP alpha and a polypeptide that binds to and triggers a TRAIL receptor or Fas. Also provided is a...
9873740 Methods of treating cancer using PD-1 axis binding antagonists and TIGIT inhibitors  
The present invention describes combination treatment comprising a PD-1 axis binding antagonist and an agent that decreases or inhibits TIGIT expression and/or activity and methods for use...
9873718 Structure-based peptide inhibitors of P53 aggregation as a new approach to cancer therapeutics  
This invention relates, e.g., to an inhibitory peptide or CPP inhibitor which specifically binds to p53 having an aberrant conformation (e.g., is aggregated or misfolded) and inhibits p53...
9873711 Multimeric dual-modality breast cancer diagnostic agents  
The present invention describes dual-modality probes. In particular, the present invention discloses hydroxyapatite specific multimeric bisphosphonate dual-modality MRI and optical probes.
9873699 Anti-cancer agents  
An anti-cancer agent having the formula: wherein Ph is a phenyl group and Ar is an aromatic group independently selected from the group consisting of phenyl, 2-bromophenyl, 4-bromophenyl,...
9873670 Arylquinoline and analog compounds and use thereof to treat cancer  
The subject technology relates to arylquinoline compounds and their use for treating cancer or cancer metastasis. The compounds of the subject technology promote cells to secrete a pro-apoptotic...
9872928 Diagnostic agent for therapeutic effect on cancer  
The present invention provides a diagnostic agent for a therapeutic effect on cancer, containing a compound represented by formula (1-0). (In formula (1-0), R represents —O(CH2)n—, —O(CH2)nOC2H4—,...
9872925 Vitamin B6-coupled poly(ester amine) as gene carrier and application in cancer gene therapy  
The present invention relates to a vitamin B6-coupled poly(ester amine) (VBPEA) as a gene carrier and a method for preparing the gene carrier. Moreover, the present invention relates to a gene...
9872921 DE-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy  
The present invention generally provides compositions methods and composition relating to the diagnosis and/or treatment of cancers having a cell surface de-N-acetylated sialic acid antigen, e.g.,...
9872912 Method for treating pancreatic cancer  
A method for treating pancreatic cancer is provided. The method comprises administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical formulation, wherein the...
9872909 Method for enhancing specific immunotherapies in cancer treatment  
Methods and compositions of the invention relate to the enhancement of specific immunotherapies in cancer treatment. In particular, aspects of the invention relate to novel approaches to boost...
9872903 Targeting thymidine kinase photosensitizer and pharmaceutical composition and use for cancer treatment thereof  
A targeting thymidine kinase photosensitizer and pharmaceutical composition and use for cancer treatment thereof is provided, which improves the selectivity of photosensitizers to tumor cells, has...
9872891 Peptides for the treatment of cancer  
The present invention relates to an isolated peptide for use in the treatment of cancer consisting of 12 to 50 amino acid residues comprising: at least two beta-strands, or at least two...
9872868 Mitochondrially-targeted electrophilic compounds and methods of use for the treatment of cancer  
The present invention provides methods, compounds, compositions and kits including mitochondrially-targeted electrophilic (MTE) compounds that are useful for treating cancer.
9869677 Methods of developing a prognosis for pancreatic cancer and predicting responsiveness to cancer therapeutics  
Methods of predicting responsiveness of a cancer in a subject to a cancer therapy including a VEGF targeting agent are provided herein. The methods include detecting the expression level of at...
9868993 Methods of diagnosing or treating prostate cancer using the ERG gene, alone or in combination with other over or under expressed genes in prostate cancer  
The present invention relates to oncogenes or tumor suppressor genes, as well as other genes, involved in prostate cancer and their expression products, as well as derivatives and analogs thereof....
9868992 Tissue and blood-based miRNA biomarkers for the diagnosis, prognosis and metastasis-predictive potential in colorectal cancer  
Methods and compositions for the diagnosis, prognosis and classification of cancer, especially colorectal cancer, are provided. For example, in certain aspects methods for cancer prognosis using...
9868954 Reduction of TGFβ signaling in myeloid cells in the treatment of cancer  
Methods of inhibiting metastasis in cancer patients are provided, wherein the methods comprise reducing TGFβ signaling, for example, by reducing TGFβ receptor II expression in myeloid cells....
9868784 Antibodies against the S100P protein for the treatment and diagnosis of cancer  
The present invention relates to the use of antibodies against the S100P protein for the prevention and/or treatment of cancer; and to methods and kits for diagnosing cancer in vitro by means of...
9868705 Tetra-aryl cyclobutane inhibitors of androgen receptor action for the treatment of hormone refractory cancer  
The present disclosure provides tetra-substituted cyclobutane inhibitors of Androgen Receptor Action, and methods of using such inhibitors, for the treatment of hormone-refractory cancers.
9867865 Mesalamine for the treatment of cancer  
Methods of treating renal cancer, including renal cell carcinoma, using mesalamine are disclosed herein. Mesalamine can be administered as a monotherapy or as part of a comprehensive treatment...
9867807 Compositions and methods for drug-sensitization or inhibition of a cancer cell  
The disclosure provides rifamycin and rifamycin derivative compositions, including rifabutin and rifabutin derivative compositions able to cause drug-sensitization in a cancer cell or inhibition...
9863960 Method, array and use for determining the presence of pancreatic cancer  
The present invention relates to a method for determining the presence of pancreatic cancer in an individual comprising or consisting of the steps of: (a) providing a sample to be tested from the...
9863953 Method for determining prognosis of cancer  
The present invention relates to a method for determining prognosis of cancer in a subject, which comprises the step of detecting phosphorylation of a tyrosine residue at position 2681 of TRIO in...
9863949 Method for predicting and evaluating responsiveness to cancer treatment with DNA-damaging chemotherapeutic agents  
Provided herein are methods directed to the prediction and early assessment of the efficacy of cancer treatment regimens, in particular in patients undergoing therapy with a DNA-damaging...
9863005 Endometrial phase or endometrial cancer biomarkers  
Methods for detecting endometrial diseases or an endometrium phase in a subject are described comprising measuring endometrial markers or polynucleotides encoding the markers in a sample from the...
9863002 Genetic determinants of prostate cancer risk  
Described are methods of determining if a subject has a genetic predisposition to developing prostate cancer (PCa), e.g., an American or Caribbean subject of African descent and of reducing their...
9862944 Antisense oligonucleotides for treatment of cancer stem cells  
The invention provides oligonucleotides complementary to a non-coding chimeric mitochondrial RNA as well as compositions and kits comprising the same, and their use in treating and preventing...
9862774 Pharmaceutical composition for treatment and/or prevention of cancer  
It is intended to provide a CAPRIN-1-targeting antibody superior in antitumor activity to conventional antibodies, and use thereof as a therapeutic and/or preventive agent for a cancer. The...
9862714 Methods and compositions useful in treating cancer and reducing Wnt mediated effects in a cell  
Provided herein are novel compounds, pharmaceutical compositions for use, inter alia, in methods of reducing Wnt-mediated effects and treating cancer.
9862693 Compounds and methods of treating cancer  
Presented herein inter alia are novel compounds and methods of using the same for the treatment of cancers.
9862692 Highly selective anti-cancer agents targeting non-small cell lung cancer and other forms of cancer  
Described herein are analogs of 2-methyl-3-(2-ethynylthiazol-4-yl)cyclopent-2-enol and the corresponding ketone 3-(2-ethynylthiazol-4-yl)-2-methylcyclopent-2-enone, the analogs having terminal...
9861679 Method of treating cancer  
The present invention provides a method of treating cancer in a subject wherein the method comprising administering to the subject an IAP antagonist and a p38 and/or a MK2 inhibitor.
9861653 Synergistic anti-cancer composition and a process for the preparation thereof  
The present invention provides an anti-cancer lipid-based composition that kills very aggressive pancreatic cancer cells and breast cancer stem cell (CSC)-like cells. This composition is a...
9861625 Methods and compositions for treating cancer through inhibition of PI3K  
Provided herein are methods for treating cancer relating to inhibition of PI3K, as pharmaceutical compositions comprising a PI3K inhibitor and a PAK1 inhibitor.
9861624 Method of treating cancer  
This invention is directed to the treatment of cancer, particularly castration-resistant prostate cancer and osteolytic bone metastases, with a dual inhibitor of MET and VEGF.
9861342 Adjunctive ultrasound processing and display for breast cancer screening  
An adjunctive ultrasound mammography system and associated methods use an adjunctive ultrasound display configured for quick, intuitive, interactive viewing of volumetric ultrasound scans,...
9858665 Medical imaging device rendering predictive prostate cancer visualizations using quantitative multiparametric MRI models  
A user-independent, quantitative, multiparametric MRI model is developed and validated on co-registered correlative histopathology, yielding improved performance for cancer detection over single...
9858389 Method and system for determining the risk of occurrence of prostate cancer  
Clinical information, molecular information and/or computer-generated morphometric information is used in a predictive model for predicting the occurrence of a medical condition. In an embodiment,...
9857375 Cancer marker and utilization thereof  
The present invention provides a novel cancer marker that is useful in the diagnosis of urothelial cancer. The present invention uses ubiquilin 2 as a cancer marker for urothelial cancer (renal...
9857374 Biomarkers for the early detection of breast cancer  
The present invention provides reagents and methods for breast cancer detection.
9857360 Cancer analysis system  
The invention provides for detecting target subpopulations of cells that have high proliferative and renewal properties in animals, including circulating tumor cells, cancer stem cells,...