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10487362 Methods for diagnosing cancer based on small nucleolar RNA HBII-52  
Provided are compositions and methods for detecting in a sample the presence or absence, and/or the amount, of a small nucleolar RNA (snoRNA) HBII-52, also known as SNORD115. The compositions and...
10487329 Methods and compositions for the treatment of head and neck cancer  
Disclosed are methods of treating a head and/or neck squamous cell carcinoma in an individual. The method may include the step of administering to an individual a composition comprising an...
10487132 Peptides and combination of peptides for use in immunotherapy against esophageal cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10487126 Peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10487119 Peptides for diagnosis and treatment of cancer  
A method of peptide histochemical diagnosis to detect the peptide binding protein in the cancer tissue is described. This peptide binding specifically to tumor cells is linked to the dextran...
10487116 Immunotherapy against several tumors, such as lung cancer, including NSCLC  
A method of treating a patient who has glioblastoma and/or gastric cancer includes administering to said patient a composition containing a population of activated T cells that selectively...
10487108 Certain steroids and methods for using the same in the treatment of cancer  
Chemical entities that are novel compounds, pharmaceutical compositions and methods of treatment of cancer are described.
10487107 Nanoparticles, process for preparation and use thereof as carrier for amphipatic and hydrophobic molecules in fields of medicine including cancer treatment and food related compounds  
The present invention regards nanoparticles comprising a sterol and a component derived from Quillaja saponaria Molina selected from quillaja acid and quillaja saponin, which nanoparticles do not...
10485859 Peptides and combination of peptides for use in immunotherapy against breast cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10485858 Cancer stem cell targeted cancer vaccines  
Provided herein are cancer stem cell targeted cancer vaccines and methods for treating and vaccinating against cancer. Also contained herein are regimens by which cancer stem cell targeted cancer...
10485804 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Therapeutic targeting of casein kinase 1δ in breast cancer
 
The invention provides a method of inhibiting casein kinase 1δ (CK1δ), comprising contacting the CK1δ with a compound of formula (I), as defined herein; such as compound SR-3029. We demonstrate...
10485775 Receptor subtype and function selective retinoid and rexinoid compounds in combination with immune modulators for cancer immunotherapy  
Disclosed herein are methods for culturing CAR-modified immune cells with at least one Retinoic Acid Receptor and/or Retinoid X Receptor active agent.
10485773 Benzenesulfonamide derivatives and method for treating cancer  
Provided are benzenesulfonamide derivatives or pharmaceutically acceptable salts thereof. Also provided is a method for treating cancer by using a pharmaceutical composition including the...
10485772 Compositions for modulating cancer stem cells and uses therefor  
Disclosed are compositions and methods for modulating cancer stem cells. More particularly, the present invention discloses the use of lysine demethylase (LSD) inhibitors and protein kinase C...
10485769 Cholesteryl ester transfer protein (CETP) inhibition in the treatment of cancer  
In one embodiment, the invention provides methods of treatment which use therapeutically effective amounts of Cholesteryl Ester Transfer Protein (CETP) inhibitors to treat a variety of cancers. In...
RE47731 Kinase inhibitors and method of treating cancer with same  
The invention is directed to a compound represented by the following structural formula and pharmaceutically acceptable salts thereof: Compounds represented by this structural formula are kinase...
10482993 Analyzing copy number variation in the detection of cancer  
The invention provides a method for determining copy number variations (CNV) of a sequence of interest in a test sample that comprises a mixture of nucleic acids that are known or are suspected to...
10481159 IL-6 signaling and breast cancer  
The disclosure provides, inter alia, methods of detecting IL-6 signaling activity in T cells in breast cancer patients, such as breast cancer patients in remission.
10480034 Cancer biomarker and diagnostic  
The application discloses new biomarkers and methods useful in the diagnosis, prognosis and/or monitoring of, or as a therapeutic or research target for, solid tumour cancers, such as colorectal...
10480033 MiRNA-based predictive models for diagnosis and prognosis of prostate cancer  
The lack of clear predictors of prostate cancer progression leads to subjective decision-making regarding courses of treatment. The identification of new biomarkers that are predictive of...
10479997 Compositions and methods for diagnosis and treatment of prostate cancer  
The invention provides novel personalized therapies, kits, transmittable forms of information and methods for use in treating subjects having TMPRSS2:ERG positive prostate cancer, which we show is...
10479979 Method for making and using cold atmospheric plasma stimulated media for cancer treatment  
A method for preparing cold atmospheric plasma stimulated cell culture media with a cold atmospheric plasma system having a delivery port out of which an inert gas flows. The inert gas may be...
10479839 Internalizing human monoclonal antibodies targeting prostate cancer cells in situ  
This invention provides a method that allows selection of antibodies against cells (e.g., tumor cells) in situ using laser capture microdissection. By restricting antibody selection to binders of...
10479837 Methods for treating subjects having a CXC chemokine receptor 5 (CXCR5)-responsive cancer by administering fully human anti-CXCR5 antibodies  
There is disclosed compositions and methods relating to or derived from anti-CXCR5 antibodies. More specifically, there is disclosed fully human antibodies that bind CXCR5, CXCR5-binding fragments...
10479818 Immunotherapy against several tumors, such as lung cancer, including NSCLC  
A method of treating a patient who has glioblastoma and/or gastric cancer includes administering to said patient a composition containing a population of activated T cells that selectively...
10478509 Anti-DLL3 antibody drug conjugates for treating cancer  
Provided are novel antibody drug conjugates (ADCs), and methods of using such ADCs to treat proliferative disorders.
10478497 Combinations of inecalcitol with an anti-CD38 agent and their uses for treating cancer  
The present invention concerns combinations of inecalcitol with an anti-CD38 agent such as daratumumab, MOR 202 or isatuximab for the treatment of cancer, such as hematological malignancies by...
10478495 Methods for treating cancer using nanoparticle complexes of paclitaxel, cetuximab, and albumin  
The invention relates to methods for treating cancer (e.g., EGFR-expressing cancer) in a subject in need thereof, the method comprising administering to the subject a therapeutically effective...
10478494 FGFR/PD-1 combination therapy for the treatment of cancer  
Provided herein are combination therapies for the treatment of cancer. In particular, the disclosed methods are directed to treatment of cancer in a patient comprising administering an antibody...
10478480 Peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10478471 Immunotherapy against several tumors including gastrointestinal and gastric cancer  
A pharmaceutical composition contains an antibody or a fragment thereof specific for COL6A3 for the treatment of a cancer. A method of treating a cancer includes administering to a subject in need...
10478468 Method for enhancing effect of immunotherapy for cancer  
Disclosed is a method for enhancing the effect of an immunotherapy for cancer in a subject, comprising administering to the subject an effective amount of a polysaccharide extract of Astragalus...
10478465 Herbal composition for the treatment and management of cancer and method of preparation thereof  
Herbal composition for the treatment and management of cancer and method of preparation are disclosed herein. The disclosed composition includes a combination of herb and mineral components that...
10478428 Combination therapy for cancer treatment  
Combination therapies for treating cancer comprising administration of a topoisomerase-1 inhibitor and a PARP inhibitor are provided. The topoisomerase-1 inhibitor can be delivered as a liposomal...
10473662 Diagnostic and prognostic markers for cancer  
Compositions and methods useful for diagnosis and prognosis of cancer are provided. More particularly, methods for detecting breast or prostate cancer protein or nucleic acid biomarkers consisting...
10473660 Materials and methods for detecting cancer based on urinary levels of RHAMM  
The invention pertains to diagnosis and treatment of ovarian cancer (OC), cervical cancer (CC), or colorectal cancer (CRC). One embodiment of the invention provides a method of identifying OC, CC,...
10473640 Drug selection for gastric cancer therapy using antibody-based arrays  
The present invention provides methods for selecting a suitable anticancer therapy, and for identifying and predicting response for the treatment of a gastric cancer.
10472418 Composition for preventing or treating lung cancer comprising antibody against CD66C and chemotherapeutic agent  
A use of prevention or treatment of lung cancer including an antibody specifically recognizing CD66c in lung cancer or its antigen-binding fragment and a chemotherapeutic agent is provided.
10472407 Peptides, combination of peptides as targets and for use in immunotherapy against gallbladder cancer and cholangiocarcinoma and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10472402 Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC, SCLC and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10472401 Peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10472355 Cancer treatment utilizing SP-141 to bind with MDM2 and act as an inhibitor of MDM2 expression  
An SP-141 compound is a novel small molecule that can serve as a molecular-targeted chemotherapeutic agent. In one embodiment, the labeled compound can comprise SP-141, which comprises...
10471160 Labeled inhibitors of prostate specific membrane antigen (PSMA), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer  
The present invention generally relates to the field of radiopharmaceuticals and their use in nuclear medicine as tracers, imaging agents and for the treatment of various disease states of...
10471146 Cancer-cell-specific anti-transmembrane protein 180 antibody, anticancer drug, and cancer testing method  
An object of the present invention is to provide an anticancer drug capable of treating cancer by finding a target molecule specifically expressed in cancer cells and by specifically acting on the...
10471145 Methods for treating cancer using nanoparticle complexes of paclitaxel, rituximab, and albumin  
Described are stable nanoparticle complexes comprising paclitaxel, albumin and ofatumumab. The nanoparticle complexes are suitable for the treatment of cancer.
10471144 Combination of local rose bengal and systemic immunomodulative therapies for enhanced treatment of cancer  
A method for the treatment of cancer comprising administration of a therapeutically effective amount of an intralesional chemoablative pharmaceutical composition, or variant of said composition,...
10471073 Methods of reducing mammographic breast density and/or breast cancer risk  
The present disclosure is directed to generally methods and/or compositions for treating mammographic breast density and/or breast stiffness in a patient in need thereof, such as a pre-menopausal,...
10471055 Methods of treating cancer patients with farnesyltransferase inhibitors  
The present invention relates to the field of molecular biology and cancer biology. Specifically, the present invention relates to methods of treating a subject with a farnesyltransferase...
10471051 Heterocyclic inhibitors of ERK1 and ERK2 and their use in the treatment of cancer  
The present application provides novel heterocyclic compounds and pharmaceutically acceptable salts thereof. Also provided are methods for preparing these compounds. These compounds are useful for...
10471039 Method for treating skin cancer  
A method for treating skin cancer including the steps of applying an isothiocyanate functional surfactant to an area affected by skin cancer, wherein the isothiocyanate functional surfactant...