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8653039 Peptide based inhibition of caPCNA interaction in cancer  
Peptides derived from cancer specific isoform of proliferating cell nuclear antigen (caPCNA, also known as csPCNA) or from nmPCNA-interacting proteins interfere with intracellular protein-protein...
8653035 Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of glioblastoma (GBM) and other cancers  
The present invention relates to immunotherapeutic peptides and their use in immunotherapy, in particular the immunotherapy of cancer. The present invention discloses tumor-associated T-helper cell...
8653021 Targeting PAX2 for the treatment of breast cancer  
The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of...
8653006 Metabolite biomarkers for the detection of esophageal cancer using NMR  
Methods for the detection and screening of esophageal adenocarcinoma (EAC) patients and for the monitoring of EAC treatment using a panel or panels of small molecule metabolite biomarkers are...
8652839 HM1.24—utilizing cancer vaccines  
A cancer vaccine containing as an active ingredient an antigen-specific dendritic cell pulsed by an HM1.24 protein, HM1.24 peptide or transduced with an HM1.24-encoding gene, or HM1.24...
8652777 Method for the analysis of ovarian cancer disorders  
The invention relates to a method for the analysis of ovarian cancer disorders, comprising determining the genomic methylation status of one or more CpG dinucleotides in a sequence selected from...
8652478 Method for treating cancer by administering antibody to ephrin type-A receptor 7  
The present invention provides methods and compositions for treatment, screening, diagnosis and prognosis of bladder cancer, breast cancer, colorectal cancer, gastric cancer, head and neck cancer,...
8652472 Compositions and methods for diagnosing and treating cancer  
An isolated antibody that specifically binds to an extracellular domain of human DDR2 and has a therapeutic effect on a solid tumor is described. Also described is a method of treating cancer, the...
8649849 Optical methods to intraoperatively detect positive prostate and kidney cancer margins  
The present invention includes using optical spectroscopy as an innovative technique for ex-vivo demonstration of renal and prostate tumors. The apparatus and methods disclosed herein demonstrate...
8648117 Methods and compositions for treating cancer metastasis  
The present invention provides methods and compositions for treating cancer metastasis by cyclohexenone compounds.
8648108 Medical compositions for intravesical treatment of bladder cancer  
Anti-cancer coating compositions comprising 3-hydroxymethyl-5-aziridinyl-1-1-methyl-2-[1H-indole-4,7-dio ne]propenol (E09) are disclosed. More specifically, the coating compositions comprise EO9...
8648063 Potentiation of cancer chemotherapy by 7-(2, 5-dihydro-4-imidazo [1, 2-a] pyridine-3-yl-2,5-dioxo-1H-pyrrol-3-yl)-9-fluoro-1,2,3,4 tetrahydro -2-(1-piperidinyl-carbonyl)-pyrrolo [3,2,1-jk] [1,4] benzodiazepine  
An improved method for treating gastric cancer, ovarian cancer, non-small cell lung cancer, or colorectal cancer in a patient is described, as well as pharmaceutical compositions useful for the...
8648046 Compositions and methods for visualizing and eliminating cancer stem cells  
The present invention relates generally to the field of cancer diagnosis and treatment, and more particularly to compositions and methods that may be useful for eliminating cancer cells with...
8647826 Nucleic acid and corresponding protein entitled 125P5C8 useful in treatment and detection of cancer  
A novel gene (designated 125P5C8) and its encoded protein, and variants thereof, are described wherein 125P5C8 exhibits tissue specific expression in normal adult tissue, and is aberrantly...
8647627 Composition for a cancer vaccine  
Pharmaceutical compositions useful as vaccines are described containing a purified surface or excreted protein qualitatively or quantitatively associated with a type of cancer, at least one...
8647618 Method of cancer treatment  
A method and composition for treating cancer comprising administering to a patient an effective amount of attenuated Salmonella typhimurium containing a plasmid carrying the coding sequence...
8647603 Devices and methods for the treatment of cancer  
The invention relates to the treatment of cancer. In particular the invention relates to an internal therapeutic product comprising: (i) an anti-cancer component selected from one or both of: a...
8642978 Charged particle cancer therapy dose distribution method and apparatus  
The invention relates generally to treatment of solid cancers. More particularly, a method and apparatus for efficient radiation dose delivery to a tumor is described. Preferably, radiation is...
8642724 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Colon cancer related gene TOM34
 
Objective methods for detecting and diagnosing colon cancer are described herein. In one embodiment, the diagnostic method involves determining the expression level of TOM34 that discriminates...
8642655 Systems and methods for preventing cancer and treating skin lesions  
Systems and methods of using a composition containing at least one or more amino acids for topical application to skin to prevent cancer and treat skin lesions.
8642610 Dual small molecule inhibitors of cancer and angiogenesis  
The present invention provides analogs and derivatives of thalidomide which inhibit cancer and angiogenesis. The present invention further provides compounds which disrupt microtubule...
8642604 Substituted pyrazolo[3,2-d]pyrimidines as anti-cancer agents  
The present invention provides novel compounds that are antagonists of PI3 kinase, PI3 kinase and tyrosine kinase, PI3 kinase and mTOR, or PI33 kinase, mTOR and tyrosine kinase.
8642562 Polysialic acid derivatives, methods of production, and uses in enhancing cancer antigen production and targeting  
The present invention relates to compositions and methods of their production and use, including use in increasing de-N-acetyl sialic acid antigen of a mammalian cell and methods that exploit the...
8642554 Smac mimetic dimers and trimers useful as anti-cancer agents  
The invention provides small molecule mimics of the Smac peptide that are dimer-like or trimer-like compounds having two or three amide-containing domains connected by a linker. These compounds are...
8642515 Genetic determinants of prostate cancer risk  
Described are methods of determining if a subject has a genetic predisposition to developing prostate cancer (PCa).
8642347 Urinary CA125 peptides as biomarkers of ovarian cancer  
The present invention is directed to diagnostic methods based upon the detection of peptides derived from the degradation of CA125. In particular, it is concerned with assays of urine samples...
8642280 Teneurin and cancer  
The present invention relates to a method for treating cancer, for instance brain tumors, in a subject by inhibiting a teneurin by administering to said subject a therapeutically effective amount...
8642271 Aberrant methylation of C6Orf150 DNA sequences in human colorectal cancer  
This application describes methods and compositions for detecting and treating C6Orf150-associated neoplasia. Differential methylation of the C6Orf150 nucleotide sequences has been observed in...
8642270 Prognostic biomarkers to predict overall survival and metastatic disease in patients with triple negative breast cancer  
The present invention relates to a method for prognosing cancer in a subject with triple negative (TN) breast cancer, whose tumors lack expression of the estrogen receptor (ER), the progesterone...
8642267 Biomarker for diagnosis of canine cancer  
The present invention is related to a biomarker for diagnosis of canine cancer, wherein the biomarker is KMO (kynureinie 3-monooxygenase) gene, and the canine cancers including CTVT (canine...
8642032 Method for screening of patient to be administered with pharmaceutical agent comprising anti-cancer antibody as active ingredient  
The present invention provides a method for screening a patient to be administered with a pharmaceutical composition which comprises an anti-cancer antibody as an active ingredient, said method...
8642009 Diagnostic system for the detection of skin cancer  
Methods and compositions are provided for the analysis of skin surfaces to determine the presence of neoplastic tissue. In the methods of the invention, a composition comprising a florescent probe...
8642007 Method and compound for treatment of cancer using phosphorous-32 labeled DNA  
This invention provides a combination of a gene and isotope therapy that is applied to a cancerous tissue to selectively kill that associated cancer cells with minimal negative effects on...
8641592 Method and device for image guided dynamic radiation treatment of prostate cancer and other pelvic lesions  
A method and device for image guided dynamic radiation treatment of prostate cancer and other pelvic lesions including: 1) a unique fan geometry of radiation sources; 2) a special collimation...
8637818 Magnetic field control method and apparatus used in conjunction with a charged particle cancer therapy system  
The invention comprises a charged particle beam acceleration, extraction, and/or targeting method and apparatus used in conjunction with charged particle beam radiation therapy of cancerous tumors....
8637683 Macrocyclic lactone derivatives for the treatment of cancer  
The present invention provides compounds represented by formula (1): wherein, R1, R2, R3 and R4 are as defined in the specification, in all their stereoisomeric and tautomeric forms and mixtures...
8637679 Process for the isolation of organic compounds useful for the treatment of cancer  
The present invention relates to two main components, mahanine and mahanimbine (dehydroxy-mahanine) from Murraya koenigii for the treatment of glioblastoma and cervical carcinoma. Mahanimbine...
8637672 Cyclopropyl dicarboxamides and analogs exhibiting anti-cancer and anti-proliferative activities  
The disclosed compounds are useful in the treatment of mammalian cancers and especially human cancers. Compounds, pharmaceutical compositions, and methods of Formula I are disclosed: or a...
8637563 Non-peptide thrombopoietin receptor agonist in the treatment of cancer and pre-cancerous syndromes  
Invented is a method of treating cancer or a pre-cancerous syndrome in a mammal, including a human, in need thereof which comprises the administration of an effective amount of a non-peptide...
8637554 Methods for treating thyroid cancer  
The invention provides methods for enhancing iodine absorption in a thyroid in a subject and treating thyroid cancer by administering to the subject a composition which includes a multi-kinase...
8637490 Anti-cancer agents  
Described herein are compounds that may be selectively activated to produce active anti-cancer agents in tumor cells. Also disclosed are pharmaceutical compositions comprising the compounds, and...
8637481 Sensitizing agents for cancer therapy, methods of use and methods for the identification thereof  
There is provided herein methods, compounds and methods for identifying compounds, for sensitizing a subject with cancer to a cancer therapy by inhibiting or down-regulating UROD.
8637467 Pharmaceutical being used for treating cancer and fibrosis disease and the composition and uses thereof  
Provided is the composition of a peptide and its mutagenic version, or other derivatives with the same 3-D structure with activity to bind the extracellular domain of PDGFR-α, or -β, but does not d...
8637265 Cathepsin E as a marker of colon cancer  
Elevated levels of cathepsin E (catE) are demonstrated to be diagnostic of intestinal forms of cancer, such as colorectal cancer. Elevated levels of cathepsin E (catE, monomeric forms) are...
8637240 Use of gene expression signatures to determine cancer grade  
Signatures indicative of cancer grades are based on over- and under-expression of 214 genes that characterize expression patterns in CD133+ cells.
8634610 System and method for assessing cancer risk  
Methods and systems for determining a probabilistic assessment of a person developing cancer are disclosed. The probabilistic assessment may include receiving a digital breast image of a person,...
8633224 Hemiasterlin derivatives and uses thereof in the treatment of cancer  
The present invention provides compounds having formula (I): and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of cancer, wherein R1-R7,...
8633174 Compounds for use in the treatment of cancer  
Pharmaceutical compositions comprise a first compound of Formula I or a physiologically acceptable salt thereof, and a cyto-protective amount of a manganese chelate of N,N′-dipyridoxyl e...
8633154 Cyclodepsipeptides with antineoplastic activity and methods of using to inhibit cancer and microbial growth  
The present invention is directed to cyclodepsipeptide compounds having antineoplastic and/or antimicrobial activity, preferably Kitastatin 1. The present invention is further directed to methods...
8633149 Targeting PAX2 for the treatment of breast cancer  
The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of...