Sign up


Match Document Document Title
8846633 Method for inhibiting cancer stem cell like properties and chemoradioresistant properties of cancer or tumor cells with microRNA145  
The present invention provides a method for inhibiting cancer stem cell like properties and chemoradioresistant properties of cancer or tumor cells comprising delivering miR145 to the cancer or...
8846630 Pharmaceutical composition for treating cancer  
The present invention provides a pharmaceutical composition for treating cancer, comprising at least one selected from deoxyribonucleic acids (DNA) for encoding small interfering RNA (siRNA) which...
8846629 Id-1 and Id-2 genes and products as therapeutic targets for treatment of breast cancer and other types of carcinoma  
A method for treatment and amelioration of breast, cervical, ovarian, endometrial, squamous cells, prostate cancer and melanoma in a patient comprising targeting Id-1 or Id-2 gene expression with...
8846623 Cancer-targeting peptides and uses thereof in cancer treatment and diagnosis  
Cancer-targeting peptides having a PX1LX2 motif, in which X1 is His or an amino acid residue with a hydrophobic side chain and X2 is Pro, Phe, or Trp. Also disclosed herein are conjugates...
8846325 Methods of cancer diagnosis and therapy targeted against a cancer stem line  
Improved methods for treatment of cancer which involve the targeting of slow-growing, relatively mutationally-spared cancer stem line are provided. These methods are an improvement over previous...
8846316 Biomarker for human liver cancer  
The disclosure relates to a method for determining incidence of liver cancer in a subject, including detecting methylation level or expression level of one microRNA miR-129-2 in a bio-sample from...
8846311 Map kinase kinase kinase kinase 3 (MAP4K3) as a biomarker and therapeutic target for autoimmune disease, cancer, inflammation and IL-17-associated disease  
Methods for identifying a therapeutic agent for treating a Germinal Center Kinase (GCK)-Like Kinase (GLK)-mediated disease are disclosed. Methods for detecting a modulation of GLK signaling by a...
8846059 Extracellular matrix adjuvant and methods for prevention and/or inhibition of ovarian tumors and ovarian cancer  
Compositions suitable for use as ovarian cancer and/or tumor adjuvants in the preparation of ovarian cancer vaccines, particularly those vaccines useful in the treatment of human ovarian cancer,...
8846043 Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer  
A novel gene 0161P2F10B (also designated 161P2F10B) and its encoded protein, and variants thereof, are described wherein 161P2F10B exhibits tissue specific expression in normal adult tissue, and...
8846005 APCDD1 inhibitors for treating, diagnosing or detecting cancer  
The invention provides, inter alia, methods for methods for treating cancer, compositions for treating cancer, and methods and compositions for diagnosing and/or detecting cancer. In particular,...
8843320 Use of gene expression profiling to predict survival in cancer patient  
Gene expression profiling in multiple myeloma patients identifies genes that distinguish between patients with subsequent early death or long survival after treatment. Poor survival is linked to...
8841866 Charged particle beam extraction method and apparatus used in conjunction with a charged particle cancer therapy system  
The invention comprises a charged particle beam extraction method and apparatus used in conjunction with charged particle beam radiation therapy of cancerous tumors. The system uses a...
8841281 Transition metal complexes of amino acids and related ligands and their use as catalysts, anti-microbials, and anti-cancer agents  
The present invention relates to the fields of chemistry and pharmaceuticals. Embodiments of the present invention provide transition metal complexes of amino acids. Transition metal complexes of...
8841277 Methods for treating non-small cell lung cancer using 5-azacytidine  
The present disclosure provides methods for treating subjects having non-small cell lung cancer, wherein the methods comprise administering to the subject a cytidine analog, such as 5-azacytidine....
8841274 Protein arginine N-methyltransferase-5 method of cancer treatment  
A method for the treatment of a proliferative disease comprising providing a E2F-1 protein which is arginine-methylation defective or administering a substance which reduces the expression and/or...
8841268 Method and kit for detection of cancer, and therapeutic agent for cancer  
The object aims to comprehensively analyze miRNA that undergoes epigenetic silencing in cancer to identify miRNA associated with cancer, elucidate the role of the identified miRNA in cancer, and...
8841125 Cancer tissue-derived cell mass and a process for preparing same  
Disclosed is a novel cell mass derived from a cancer tissue, which can reflect the in vivo behavior of a cancer cell correctly. Also disclosed is a process for preparing the cell mass....
8841081 Method of treating metastatic stage prostate cancer  
The invention provides methods and dosing regimens for treating metastatic stage prostate cancer in a subject using degarelix, as well as related methods of using degarelix in a subject identified...
8840886 Method of treating cancer with DLL4 antagonist and chemotherapeutic agent  
The invention provides methods for treating various types of cancer/tumor by administering the combination of Dll4 antagonists, in particular, Dll4 antibodies and fragments thereof that...
8840881 Methods and compositions for treating prostate cancer or inducing a humoral immune response against prostate cancer  
The present invention relates to prostate cancer markers, compositions comprising such markers, and methods of using such markers to induce or increase an immune response against prostate cancer....
8840678 Drug-eluting bioabsorbable renal artery stent for renal cancer and inflammatory disorders  
Methods of treating renal cancers and other kidney-related inflammatory disorders with a bioabsorbable polymer scaffold (such as a stent) are described. The treatments are provided as alternative...
8835629 Anti-cancer agents  
The present invention provides a compound of Formula (I), or a pharmaceutical acceptable derivative, salt or prodrug thereof. Further provided is a method of treatment of cancer in a subject...
8835606 Anti-cancer antibodies with reduced complement fixation  
The invention provides modified antibodies directed against GD2 that have diminished complement fixation relative to antibody-dependent, cell-mediated cytotoxicity, which is maintained. The...
8835605 Uses of cancer-targeting peptides in cancer diagnosis  
Cancer-targeting peptides and uses thereof in cancer diagnosis.
8835506 Methods and related compositions for the treatment of cancer  
A method of treatment and/or prevention of cancer comprises administering agents which cause increased intracellular granularity in cancer cells, at least in an amount sufficient to inhibit...
8835478 Treatment for cancer  
The present invention provides methods for the treatment of tumors, comprising administration of an effective amount of at least one taxoid and an effective amount of at least one benzimidazol...
8835473 Methods and compositions for treating cancer  
The present invention provides methods of treating cancer using 2-amino-6-trifluoromethoxybenzothiazole (riluzole). In one aspect, the present invention provides methods of reducing cancer cell...
8835450 Combination of inhibitor of B-Raf and an inhibitor of Akt in the treatment of cancer  
The present invention relates to a method of treating cancer in a human and to pharmaceutical combinations useful in such treatment. In particular, the method relates to a cancer treatment method...
8835433 Optically pure diastereomers of 10-Propargyl-10-deazaaminopterin and methods of using same for the treatment of cancer  
The present invention relates to diastereomers of 10-propargyl-10-deazaaminopterin, compositions comprising optically pure diastereomers of 10-propargyl-10-deazaaminopterin, in particular the two...
8835401 Treatment of cancer by inhibition of IGFBPs and clusterin  
Agents that reduce the amount of IGFBP-2 and/or IGFBP-5 and that are known to be useful in the treatment of cancer result in increased expression of the protein clusterin. Since clusterin can...
8835164 Cell line stably expressing mutated oncoprotein E6 and method of screening anticancer compound of uterine cervical cancer using the same  
Disclosed are a cell line that expresses protein of Seq. No. 1, and a method for screening an anticancer compound of uterine cervical cancer by using the same. The stable cell line that expresses...
8835124 Method for treating cancer with agents that bind phosphorylated CDC27  
The presence of phosphorylated Cdc27 in cancer cells is utilized to identify patients likely to benefit from treatment with a chemotherapeutic agent that binds to, or binds to and crosslinks,...
8835110 DNA integrity assay (DIA) for cancer diagnostics, using confocal fluorescence spectroscopy  
The present invention relates, e.g., to a method for determining the size distribution of DNA molecules in a sample comprising cell-free nucleic acid, comprising labeling the DNA with a...
8834938 Use of arsenic for cancer therapy protection  
A method of inhibiting, preventing, or reducing damage to non-cancerous cells in a human subject during chemotherapeutic treatment or radiation treatment of cancer cells in the human subject...
8834878 Antigen-antibody cancer recognition system  
A method for the treatment of cancer is provided wherein a cancer recognition (CARE) antigen or CARE antibody is administered to a patient. Administration of the CARE antigen or antibody will...
8834873 Method for detecting and controlling cancer  
Methods are provided for treating cancer metastasis by administering a therapeutic composition targeting a kinase substrate cascade.
8834838 Non-invasive diagnostic agents of cancer and methods of diagnosing cancer, especially leukemia and lymphoma  
The present invention is directed to novel non-invasive diagnostic tools to image cancers, especially, leukemia and non-Hodgkin's lymphomas (NHL) with minimal toxicity in vivo. The present...
8829162 In vitro method for diagnosing prostate cancer  
The invention relates to an in vitro method for diagnosing prostate cancer and to antibodies and fragments thereof directed against CK2-α and their use for the diagnosis and prognosis of prostate...
8829025 Anti-cancer compounds  
The present invention relates to anti-cancer compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides analogs of the known anti-cancer...
8828984 Gold(III) complexes containing N-heterocyclic carbene ligand, synthesis, and their applications in cancer treatment and thiol detection  
Provided herein is a method of synthesis of Au(III)-NHC complexes, a pharmaceutical composition comprises thereof. Also provided herein are the methods for the treatment and prevention of...
8828964 Cancer cell identification marker and cancer cell proliferation inhibitor  
Disclosed is an identification marker which can be utilized for detection of various human cancer cells and whose expression closely relates to malignant alteration of cells, and compositions for...
8828944 Compounds and uses thereof to induce an immunogenic cancer cell death in a subject  
The present invention relates to the fields of genetics, immunology and medicine. The present invention more specifically relates to in vitro or ex vivo methods for determining the susceptibility...
8828657 Susceptibility variants for lung cancer  
The present invention discloses certain genetic variants as susceptibility variants for lung cancer. The invention relates to methods of risk assessment using such variants. The invention further...
8828451 Akt sensitization of cancer cells  
Most human tumors find ways to resist anticancer drug monotherapy. Akt is considered a likely peptide providing such monotherapy drug resistance. Data indicates that Akt chemoresistance is induced...
8828398 Pharmaceutical composition for treating and/or preventing cancer  
According to the present invention, a cancer antigen protein to be specifically expressed on the surfaces of cancer cells is identified and thus the use of an antibody targeting the cancer antigen...
8828392 Histone deacetylase (HDAC) inhibitors (PXD101) for the treatment of cancer alone or in combination with chemotherapeutic agent  
The present invention relates generally to methods for treating cancer. In one respect, the present invention relates to a method of treating a hematological cancer (e.g., multiple myeloma,...
8828391 Method for EGFR directed combination treatment of non-small cell lung cancer  
The present invention relates to a method of treating patients suffering from cancers driven by deregulated Human Epidermal Growth Factor Receptor (HER/Human EGFR), wherein an irreversible...
8828387 Antibody having anti-cancer activity  
By utilizing an SST-REX method, a cDNA encoding a protein expressed on a cell surface or secreted from the cell was selected from a cDNA library derived from a cancer cell line. Monoclonal...
8828381 Co-administration of CG250 and IL-2 or IFN-alpha for treating cancer such as renal cell carcinomas  
A method for enhancing the therapeutic effect of cytokine treatment is disclosed. More specifically the present invention relates to a method for administering to a tumor patient a therapeutic...
8828378 Targeted vectors for cancer immunotherapy  
This invention provides compositions and methods for treating cancer. More specifically this invention is directed to a targeted retroviral vector comprising a cytokine gene that can be...