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9134313 Method of detecting colorectal cancer of stages 0 to I  
A tumor marker comprising diacetylspermine, and a method of evaluating the state of a tumor, comprising reacting an antibody to diacetylspermine with a biological sample to thereby detect...
9134298 Compositions and methods to prevent cancer with cupredoxins  
The present invention relates to compositions comprising peptides that may be variants, derivatives and structural equivalents of cupredoxins that inhibit the development of premalignant lesions...
9134297 Method and compositions for treating cancer and related methods  
The present invention relates to anti-cancer therapeutics. In certain aspects, cancers are treated with a combination of an anti-EGFR agent and an agent that increases the activity of the KLF6...
9134293 Cancer marker and therapeutic target  
Chemokine receptor CCR4 and its ligands CCL1 7 and CCL22 are used as markers for the identification and/or staging of cancer. The level of CCR4, CCL17 and CCL22 are found to increase during...
9133523 Compositions and methods for detecting cancer metastasis  
The present invention encompasses compositions and methods for detecting cancer metastasis.
9133242 Peptide for use as a medicament, in particular for the treatment of cancer  
The invention relates to a peptide having the sequence SEQ.1: INWLKIAKKVAGML-NH2 and one or more of the variants thereof selected from among the sequences SEQ.2 to SEQ.25, or one of the mixtures...
9133183 Imidazolidinones and analogs exhibiting anti-cancer and anti-proliferative activities  
Described are compounds of Formula I which find utility in the treatment of cancer, autoimmune diseases and metabolic bone disorders through inhibition of c-FMS (CSF-1R), c-KIT, and/or PDGFR...
9133136 Dual small molecule inhibitors of cancer and angiogenesis  
The present invention provides analogs and derivatives of thalidomide which inhibit cancer and angiogenesis. The present invention further provides compounds which disrupt microtubule...
9133097 Use of unsaturated sphingosine compounds as chemotherapeutic agents for the treatment of cancer  
The present invention is directed to unsaturated sphingosine compounds which are useful as therapeutic agents for the treatment of cancer and for the treatment of other diseases including diabetes...
9132280 Use of fusarochromanone and its derivatives in the diagnosis and treatment of cancer and other diseases  
A method of photodynamic therapy to treat diseased cells in an animal is generally provided. According to the method,...
9132178 Cytotoxic T lymphocyte inducing immunogens for prevention treatment and diagnosis of cancer  
The present invention relates to compositions and methods for the prevention, treatment, and diagnosis of cancer, especially carcinomas, such as lung carcinoma. The invention discloses peptides,...
9132177 Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of gastric cancer and other cancers  
The present invention relates to immunotherapeutic peptides and their use in immunotherapy, in particular the immunotherapy of cancer. The present invention discloses tumor-associated T-helper...
9132158 Anti-cancer extract and compounds  
The present invention relates to a new approach for treating a cancer or fibrosis, such as hepatocellular carcinoma, or liver fibrosis using an extract from a plant of Graptopetalum sp., Rhodiola...
9132146 Furin-knockdown and GM-CSF-augmented (FANG) cancer vaccine  
Compositions and methods for cancer treatment are discloses herein. More specifically the present invention describes an autologous cancer vaccine genetically modified for Furin knockdown and...
9132118 Taxane analogs for the treatment of brain cancer  
Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or...
9132102 Stilbene analogs and methods of treating cancer  
Stilbene analogs and pharmaceutical compositions that are useful for the treatment of various cancers, including without limitation, colorectal cancer (CRC) and breast cancer are disclosed. The...
9131668 Tumor model system useful to study multistage cancer  
The present invention relates to a method of developing a Tumor Model System. The invention deals with a tumor model system with adhesion deprived cells. This observation provides a new method for...
9128096 Methods for determining cancer resistance to histone deacetylase inhibitors  
Described herein are methods and compositions for determining whether a particular cancer is resistant to or susceptible to a histone deacetylase inhibitor or to histone deacetylase inhibitors....
9128095 Diagnosis or prognosis of lung cancer and colorectal cancer based on expression level of glutaredoxin 3  
The present invention relates to a biomarker for diagnosing lung cancer and colorectal cancer containing glutaredoxin 3 as an active ingredient, and a kit for diagnosing lung cancer and colorectal...
9127284 Modified bacteria and their uses thereof for the treatment of cancer or tumor  
Described herein is a method of treatment of cancer or tumor using a modified bacteria or composition comprising the modified bacteria. In certain embodiments, the method is in combination with...
9127273 UNC-45A splice variants based cancer diagnostics and therapeutics  
Methods and compositions to diagnose and treat cancers using UNC-45A splice variants are disclosed. Expression of a human UNC-45A929 splice variant that is shorter than UNC-45A944 splice variant...
9127011 Pharmaceutical compositions for the treatment of cancer and other diseases or disorders  
This invention provides novel pharmaceutical compositions of the compound of formula (I): or a pharmaceutically acceptable salt thereof, that are suitable for the bulk production of an oral...
9126981 Alpha helix mimetic compositions for treating cancer and other CBP/catenin-mediated diseases and conditions  
Alpha-helix mimetic structures and compounds represented by the formula (I) wherein the general formula and the definition of each symbol are as defined in the specification, a compound relating...
9126911 Anti-cancer compositions and methods  
Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the...
9126910 Anti-cancer compositions and methods  
Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the...
9125913 Bcl-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases  
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 or Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which are expressed...
9125897 Cancer treatment with endothelin receptor antagonists  
The present invention relates to therapeutic protocols and pharmaceutical compositions designed to treat and prevent cancer. More specifically the present invention relates to a novel method of...
9125835 Synergistic combinations to reduce particle dose for targeted treatment of cancer and its metastases  
Non-Small Cell Lung Carcinomas (NSCLCs) are treated with Gel Micro-Particles (GMPs) that passively accumulate in the lungs and contain Nano-Particles (NPs) combining one or more therapeutic agents...
9125583 Detection of cancer with electrical impedance tomography  
The use of nanoparticles for imaging a tumor in a mammal using electrical impedance tomography. The nanoparticles comprise a core of metal and/or semiconductor atoms to which are linked ligands...
9121854 Method for treating cancer or cancer metastasis  
Use of a polynucleotide encoding or a polypeptide comprising at least the extra-cellular IPT-3 and IPT-4 domains of hepatocyte growth factor receptor for the screening and/or development of...
9121069 Diagnosing cancer using genomic sequencing  
Methods, systems, and apparatus determine whether a first chromosomal region exhibits a deletion or an amplification associated with cancer in a sample from a subject (e.g., where the sample...
9121049 Pharmaceutical composition for elevating radio-sensitivity of cancer cells, pharmaceutical composition for detecting cancer cells with radio-sensitivity, and detection method thereof  
The present invention relates to a pharmaceutical composition for elevating radiation-sensitivity of cancer cells, which comprises: a nanoparticle containing with a first element, which is iron,...
9120860 Protein involved in ovarian cancer  
The present invention relates to new uses of CDCP1 in the diagnosis, screening, treatment and prophylaxis of ovarian cancer. The invention also provides compositions comprising CDCP1, including...
9120852 Antibody for the diagnosis and/or prognosis of cancer  
The present invention relates to the field of prognosis and/or diagnosis of a proliferative disease in a patient. More particularly, the invention relates to novel antibodies capable of binding...
9120760 Fluoro-homoneplanocin A and nucleoside derivatives, method for the synthesis thereof, and the pharmaceutical compositions comprising the same as an active component for treatment of cancer  
The present invention relates to a fluoro-homoneplanocin A, its nucleoside derivative, and synthetic methods. The novel fluoro-homoneplanocin A and its nucleoside derivative in the present...
9119862 Compositions, methods and kits for treating cancer  
Compositions, kits and methods for treating leukemia in a subject (e.g., human) include a first anti-cancer drug consisting of: Δ12-prostaglandin J3 or a derivative thereof, or a prostaglandin D...
9119856 Method for treating cancer using a dihydropyrimidine derivative  
A method of treating cancer using a dihydropyrimidine derivative includes administering to a patient a therapeutically effective amount of a dihydropyrimidine derivative having the following...
9119855 Compositions and methods for treatment of the side-effects associated with administration of cancer chemotherapeutic agents  
A composition and method for the treatment of the side-effects associated with the administration of cancer chemotherapeutic agents involves the oral ingestion of a slow release capsule containing...
9119854 Methods for treating cancer using combination therapy  
Provided herein are methods for treating or preventing a cancer, comprising administering an effective amount of a substituted quinazolinone compound and an effective amount of...
9119839 Cancer treatment  
The present invention relates to methods of treating cancer, such as melanoma, by administering a CTLA4 antagonist to a subject with a serum C-Reactive Protein (CRP) concentration that is less...
9119801 Cancer vaccine composition  
A cancer vaccine composition for human leukocyte antigen (HLA)-A*0206-positive persons, comprising a protein product of the tumor suppressor gene WT1 or a partial peptide thereof.
9116216 MR compatible compression based nuclear imaging system for breast cancer  
An apparatus combines magnetic resonance (MR) and nuclear imaging of human breast for cancer diagnosis. An MRI system including an MR breast RF coil is combined with a nuclear imaging system...
9115406 Synthetic lethality in cancer  
There is described herein compounds, compositions and methods for inducing synthetic lethality in a cancer cell(s).
9115371 Reduction of TGF beta signaling in myeloid cells in the treatment of cancer  
Methods of inhibiting metastasis in cancer patients are provided, wherein the methods comprise reducing TGFβ signaling, for example, by reducing TGFβ receptor II expression in myeloid cells....
9115337 Chimeric adenoviruses for use in cancer treatment  
The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of...
9115200 Pharmaceutical composition for treating cancer using a monoclonal antibody having immunological reactivity with CAPRIN-1  
According to the present invention, a cancer antigen protein to be specifically expressed on the surfaces of cancer cells is identified and thus the use of an antibody targeting the cancer antigen...
9115162 Effective treatment of tumors and cancer with triciribine and related compounds  
The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat tumors and cancer by one or a combination of (i) administering triciribine...
9114163 Medication against breast cancer and related diseases  
The present invention relates to novel uses of a steroid compound, which specifically binds to the androgen receptor (AR) but which is not metabolized by aromatase to a process for their...
9114118 Compounds and compositions for the treatment of cancer  
New uses for phenylketone carboxylate compounds and substituted aromatic compounds of Formula I, Formula I.1, Formula I.2, Formula IA, Formula IB, Formula IC and Formula II and their...
9114117 Compounds effective against cancer  
The present invention describes a Composition, comprising one or more compounds selected from the group consisting of a) compound (I) which is ethacrynic acid bezafibrate, fenofibrate, and/or...