Match Document Document Title
9125835 Synergistic combinations to reduce particle dose for targeted treatment of cancer and its metastases  
Non-Small Cell Lung Carcinomas (NSCLCs) are treated with Gel Micro-Particles (GMPs) that passively accumulate in the lungs and contain Nano-Particles (NPs) combining one or more therapeutic agents...
9125583 Detection of cancer with electrical impedance tomography  
The use of nanoparticles for imaging a tumor in a mammal using electrical impedance tomography. The nanoparticles comprise a core of metal and/or semiconductor atoms to which are linked ligands...
9121854 Method for treating cancer or cancer metastasis  
Use of a polynucleotide encoding or a polypeptide comprising at least the extra-cellular IPT-3 and IPT-4 domains of hepatocyte growth factor receptor for the screening and/or development of...
9121069 Diagnosing cancer using genomic sequencing  
Methods, systems, and apparatus determine whether a first chromosomal region exhibits a deletion or an amplification associated with cancer in a sample from a subject (e.g., where the sample...
9121049 Pharmaceutical composition for elevating radio-sensitivity of cancer cells, pharmaceutical composition for detecting cancer cells with radio-sensitivity, and detection method thereof  
The present invention relates to a pharmaceutical composition for elevating radiation-sensitivity of cancer cells, which comprises: a nanoparticle containing with a first element, which is iron,...
9120860 Protein involved in ovarian cancer  
The present invention relates to new uses of CDCP1 in the diagnosis, screening, treatment and prophylaxis of ovarian cancer. The invention also provides compositions comprising CDCP1, including...
9120852 Antibody for the diagnosis and/or prognosis of cancer  
The present invention relates to the field of prognosis and/or diagnosis of a proliferative disease in a patient. More particularly, the invention relates to novel antibodies capable of binding...
9120760 Fluoro-homoneplanocin A and nucleoside derivatives, method for the synthesis thereof, and the pharmaceutical compositions comprising the same as an active component for treatment of cancer  
The present invention relates to a fluoro-homoneplanocin A, its nucleoside derivative, and synthetic methods. The novel fluoro-homoneplanocin A and its nucleoside derivative in the present...
9119862 Compositions, methods and kits for treating cancer  
Compositions, kits and methods for treating leukemia in a subject (e.g., human) include a first anti-cancer drug consisting of: Δ12-prostaglandin J3 or a derivative thereof, or a prostaglandin D...
9119856 Method for treating cancer using a dihydropyrimidine derivative  
A method of treating cancer using a dihydropyrimidine derivative includes administering to a patient a therapeutically effective amount of a dihydropyrimidine derivative having the following...
9119855 Compositions and methods for treatment of the side-effects associated with administration of cancer chemotherapeutic agents  
A composition and method for the treatment of the side-effects associated with the administration of cancer chemotherapeutic agents involves the oral ingestion of a slow release capsule containing...
9119854 Methods for treating cancer using combination therapy  
Provided herein are methods for treating or preventing a cancer, comprising administering an effective amount of a substituted quinazolinone compound and an effective amount of...
9119839 Cancer treatment  
The present invention relates to methods of treating cancer, such as melanoma, by administering a CTLA4 antagonist to a subject with a serum C-Reactive Protein (CRP) concentration that is less...
9119801 Cancer vaccine composition  
A cancer vaccine composition for human leukocyte antigen (HLA)-A*0206-positive persons, comprising a protein product of the tumor suppressor gene WT1 or a partial peptide thereof.
9116216 MR compatible compression based nuclear imaging system for breast cancer  
An apparatus combines magnetic resonance (MR) and nuclear imaging of human breast for cancer diagnosis. An MRI system including an MR breast RF coil is combined with a nuclear imaging system...
9115406 Synthetic lethality in cancer  
There is described herein compounds, compositions and methods for inducing synthetic lethality in a cancer cell(s).
9115371 Reduction of TGF beta signaling in myeloid cells in the treatment of cancer  
Methods of inhibiting metastasis in cancer patients are provided, wherein the methods comprise reducing TGFβ signaling, for example, by reducing TGFβ receptor II expression in myeloid cells....
9115337 Chimeric adenoviruses for use in cancer treatment  
The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of...
9115200 Pharmaceutical composition for treating cancer using a monoclonal antibody having immunological reactivity with CAPRIN-1  
According to the present invention, a cancer antigen protein to be specifically expressed on the surfaces of cancer cells is identified and thus the use of an antibody targeting the cancer antigen...
9115162 Effective treatment of tumors and cancer with triciribine and related compounds  
The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat tumors and cancer by one or a combination of (i) administering triciribine...
9114163 Medication against breast cancer and related diseases  
The present invention relates to novel uses of a steroid compound, which specifically binds to the androgen receptor (AR) but which is not metabolized by aromatase to a process for their...
9114118 Compounds and compositions for the treatment of cancer  
New uses for phenylketone carboxylate compounds and substituted aromatic compounds of Formula I, Formula I.1, Formula I.2, Formula IA, Formula IB, Formula IC and Formula II and their...
9114117 Compounds effective against cancer  
The present invention describes a Composition, comprising one or more compounds selected from the group consisting of a) compound (I) which is ethacrynic acid bezafibrate, fenofibrate, and/or...
9114099 Vaccine for the prevention of breast cancer recurrence  
Provided are methods to induce and maintain a protective cytotoxic T-lymphocyte response to a peptide of the HER/neu oncogene, GP2, with the effect of inducing and maintaining protective or...
9113623 Methods and reagents for maintaining the viability of cancer cells in surgically removed tissue  
A composition and method for generating reagents and the composition of these reagents for the stabilization and preservation of viability of cancer tissue which has been surgically excised and...
9110083 Biomarkers for early detection of ovarian cancer  
Biomarker proteins that can be used in the diagnosis of early-stage ovarian cancer (OC) are described. The biomarker panels not only permit the distinction of patients with ovarian neoplasia...
9110065 Methods and compositions for the diagnosis and treatment of thyroid cancer  
Methods for detecting, diagnosing and monitoring thyroid cancer in a subject are described comprising measuring in a sample from the subject markers including Ep-ICD and EpEX. The invention also...
9110064 Methods for diagnosis and treatment of endometrial cancer  
The present invention discloses methods of using epithelial membrane protein 2 (EMP2) as a biomarker for stratification of endometrial premalignancy, diagnosing, staging and imaging of endometrial...
9110063 Assay methods for the determination of FKBPL expression level in the context of breast cancer  
Disclosed are methods that employ FKBPL as a marker for a subject's sensitivity to endocrine therapies in the treatment of cancers, and as a predictive marker of cancer progression and disease...
9109034 Precision medicine by targeting PD-L1 variants for treatment of cancer  
The invention relates to human targets of interest (TOI), anti-TOI ligands, kits compositions and method.
9108980 Pyrimidinyl and 1,3,5-triazinyl benzimidazole sulfonamides and their use in cancer therapy  
Provided herein are pyrimidinyl and 1,3,5-triazinyl benzimidazole sulfonamides, e.g., compounds of Formulae IA, IB, and IC, and their pharmaceutical compositions, preparation, and use as agents or...
9108941 Griseofulvin analogues for the treatment of cancer by inhibition of centrosomal clustering  
The invention relates to compounds of the formula (I), where the symbols have the meaning given in the specification, for use in a method for treating cancer, to use of these compounds for the...
9108923 Compounds, compositions, and methods for cancer therapy  
Compounds including various oligomers of piperlongumine and/or piperlongumine analogues as well as certain piperlongumine analogues that exhibit improved toxicity to cancer cells are disclosed....
9108919 Compounds useful for treating cancer  
A method of preventing, inhibiting, or treating cancer that includes contacting a cell with at least one compound of formula (Ia) or a pharmaceutically acceptable salt thereof: where: R...
9107962 Anthracycline-antibody conjugates for cancer therapy  
The invention relates to therapeutic conjugates with the ability to target various antigens. The conjugates contain a targeting antibody or antigen binding fragment thereof and an anthracycline...
9107961 Anti-DLL3 antibody drug conjugates for treating cancer  
Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
9107947 Anti-cancer compositions and methods  
Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present invention. Methods of treating a subject...
9107944 Immunologically modified carbon nanotubes for cancer treatment  
A method for constructing a compound of immunologically modified nanotubes and method for using the compound to deliver immunoadjuvants to tumor cells and to produce targeted, synergistic...
9107934 MicroRNA as a cancer progression predictor and its use for treating cancer  
The present invention is based on the findings that a novel function for miR142-3p in the regulation of Sox2, adenylyl cyclase 9 (AC9), and CD133 expressions, and consequently the overall stemness...
9107926 Mutant selectivity and combinations of a phosphoinositide 3-kinase inhibitor compound and chemotherapeutic agents for the treatment of cancer  
Methods and compositions are provided for treating hyperproliferative disorders in patients with a PI3K inhibitor, GDC-0032 as a single agent or in combination with chemotherapeutic agents.
9107895 Methods and compositions for imaging cancer cells  
Disclosed are compositions comprising nanoparticles and uses thereof. Such nanoparticles include gold nanoparticles conjugated to glucose or a glucose derivative, which are useful as contrast...
9107887 Combination of local and systemic immunomodulative therapies for enhanced treatment of cancer  
A method for the treatment of cancer comprising administration of a therapeutically effective amount of an intralesional chemoablative pharmaceutical composition, or variant of said composition,...
9107878 Methods of treating cancer  
The present invention relates to compositions and methods for treating an animal with a tumor or other metabolic disorder. In particular, the presently disclosed subject matter relates to methods...
9107863 Reagents and methods for cancer treatment and prevention  
The invention generally relates to the prevention and/or treatment of cancer, and, more specifically, to the treatment of tumors, including solid tumors and their metastases, without radiation or...
9107824 Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally  
One aspect of the invention relates to methods of treating cancer in a patient comprising administering intraperitoneally to a patient in need thereof a cancer treating effective amount of a...
9103833 Use of the GTPase Rab27B to diagnose and treat poor prognosis estrogen-receptor-positive breast cancer  
The present invention relates to evaluating the prognosis of patients with estrogen receptor-positive breast cancer on the basis of Rab27B expression. The invention further relates to a kit...
9102984 Systems and methods for individualized functional genomic profiling related to cancer cell growth  
The present invention provides systems and methods for identification of genes related to cancer cell growth. In particular, the present invention provides functional genomic profiling of primary...
9102761 Compositions for treatment of cancer  
The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the...
9102760 Compositions for treatment of cancer  
The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the...
9102706 Newly identified colon cancer marker and diagnostic kit using the same  
Provided are a newly identified colon cancer marker and a diagnostic kit using the same. More particularly, the present invention relates to an identified colon cancer specific marker, a...