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8686178 Derivative of 18β-glycyrrhetinic acid apt to suppress cancer cells  
The present invention is correlated with a derivative of 18β-glycyrrhetinic acid apt to suppressing cancer cells, which is selected from a group comprising of structure I and structure II: wherein ...
8686112 Methods and compositions for the detection of cancer  
A molecular probe for use in detection of cancer cells expressing an Ig superfamily cell adhesion molecule that binds in a homophilic fashion in a subject includes a targeting agent that...
8686052 Targeting agent for cancer cell or cancer-associated fibroblast  
Disclosed are a novel therapeutic agent and a novel treatment method for cancer. Specifically disclosed are: a targeting agent for a cell selected from the group consisting of a cancer cell and a...
8686030 Anti-cancer extract and compounds  
The preset invention relates to a new approach for treating a cancer or fibrosis, such as Hepatocellular carcinoma, or liver fibrosis using an extract from a plant of Graptopetalum sp., Rhodiola...
8685983 Method of treating cancer with substituted amide derivatives  
Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically...
8685954 Methods and compositions for treating cancer using proteasome inhibitors  
The present invention relates to therapeutic compositions for treating cancer or preventing the growth of cancer cells, e.g., tumor growth, in a subject. The present invention also relates to...
8685941 Drug composition cytotoxic for pancreatic cancer cells  
Disclosed herein are compositions comprising a drug combination that comprises ZD and S3I-201, Das and S3I-201, ZD and AG490, or Das and AG490. The disclosed drug combinations target two or more...
8685929 Detecting CYP24 expression level as a marker for predisposition to cancer  
This invention pertains to the discovery that an amplification of the CYP24 gene or an increase in CYP24 activity is a marker for the presence of, progression of, or predisposition to, a cancer...
8685923 Fibrillar albumin for use in inhibiting cancer growth  
A method for inhibiting survival of cancer cells in a subject is disclosed. The method comprises administering to a subject in need thereof a therapeutically effective amount of fibrillar albumin....
8685641 Method of screening compounds for treating bladder cancer  
Objective methods for detecting and diagnosing bladder cancer (BLC) are described herein. In one embodiment, the diagnostic method involves determining the expression level of a BLC-associated gene...
8685416 Compositions and methods for the treatment of cancer  
Methods for inducing an immune response to a tumor in a subject are disclosed herein. These methods include selecting a subject with a tumor and administering a therapeutically effective amount of...
8685398 Chemokine binding polypeptides capable of inhibiting the course of autoimmunity, inflammation and cancer  
Novel polypeptides comprising a chemokine-binding peptide and an Fc fragment are disclosed. The polypeptides are capable of binding to certain chemokines so as to modulate their activity. These...
8685384 Recombinant cancer cell secreting modified heat shock protein-antigenic peptide complex  
The present invention relates to methods for purifying immunogenic, prophylactically and therapeutically effective complexes of modified heat shock proteins noncovalently associated with antigenic...
8684901 Electromagnetic radiation treatment for cancer and pathological genetic regulations  
An electromagnetic radiation treatment regime includes identifying a target area of a patient that comprises at least some cancer cells, or other cells amenable to pathological genetic regulations....
8682693 Patient data mining for lung cancer screening  
A system and method for lung cancer screening is provided. The system includes a database including structured patient information for a patient population and a domain knowledge base including...
8682591 Biomarkers for ovarian cancer  
The present invention relates to a method of qualifying ovarian cancer status in a subject comprising: (a) measuring at least one biomarker in a sample from the subject and (b) correlating the...
8680282 Cyclic inhibitors of carnitine palmitoyltransferase and treating cancer  
A CPT1 inhibitor compound is represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof: or a pharmaceutically acceptable salt thereof. A pharmaceutical composition...
8680243 Diagnosis and treatment of cancer using anti-GPR49 antibody  
Antibodies that bind to a GPR49 protein and have cell proliferation inhibitory activity against cells expressing the GPR49 protein are disclosed. Cell proliferation inhibitory activities are...
8680152 Cathepsin inhibitors for the treatment of bone cancer and bone cancer pain  
The present invention is directed to methods of using compounds that are inhibitors of cysteine proteases, in particular, of both cathepsins S and K and optionally further cathepsins B and/or L in...
8680142 Ascorbate, vitamin K3 and hydroxytolans in the treatment of cancer  
The combination of compounds of the hydroxytolan family with ascorbate plus naphthoquinone (Vitamin K3; VK3), or a quinone or semiquinone analogue of VK3, kill tumor cells, inhibit tumor growth and...
8680129 Compounds, composition, methods, targets for cancer therapy  
This invention describes methods and pharmaceutical compositions for combinational cancer treatments that are capable of inducing JNK phosphorylation and induce programmed cell death. It also...
8680126 Fluorinated thiazoles for use in treating cancer  
Compounds of formula (I) or their pharmaceutically acceptable salts, or their stereoisomers or mixtures of stereoisomers, where: R1 is selected from the group consisting of: phenyl, and phenyl...
8680067 Targeting microRNAs for the treatment of liver cancer  
Provided herein are methods for the treatment of liver cancer. These methods encompass the administration of a compound comprising a modified oligonucleotide, wherein the modified oligonucleotide...
8680055 Methods for decreasing steroidogenesis in prostate cancer cells  
The present invention discloses compositions and methods for treating diseases such as cancer by targeting luteinizing hormone (LH) or its receptor (LHR) involved in androgen synthesis or...
8680045 Compositions of a peptide targeting system for treating cancer  
This invention describes a protein nanoparticle system for targeting siRNA or other drugs into tumors. The basis of the protein system is elastin-like peptides that self-assemble once exposed to...
8679760 Biomarker and method for evaluating risk of proliferation, invasion, or metastasis of cancer  
The present invention relates to a biomarker associated with a cancer and a method using the biomarker to evaluate a risk of proliferation, invasion, or metastasis of a cancer. The method of the...
8679759 Esophageal cancer markers  
The present invention is directed to methods for diagnosing cancer in a subject. Morphologically normal epithelial cells of the esophagus are assayed for marker expression. Characteristic...
8674172 Prostate cancer cell lines and their use in screening method  
The present invention relates to a prostate cancer cell line CNCM deposit number I-4126, the use thereof for preparing resistant prostate cancer cell lines, the resistant prostate cancer cell...
8674081 Methods and compositions to elicit multivalent immune responses against dominant and subdominant epitopes, expressed on cancer cells and tumor stroma  
The present invention provides a method of treating cancer by providing to a subject in need thereof an immunogenic composition comprising a nucleic acid construct encoding a polypeptide comprising...
8674079 Cancer cell migration and cancer cell invasion inhibitor  
Provided are an antibody which binds specifically PAR1 (protease activated receptor 1) or a fragment of the antibody which retains similar characteristics thereto; a composition containing the same...
8674070 Cancer-targeting peptides and uses thereof in cancer therapy  
Cancer-targeting peptides and uses thereof in cancer therapy.
8674060 Peptide ligand to impair cancer cell migration  
Loss of Wnt-5a protein expression in breast carcinoma patients is associated with a shorter recurrence-free survival as well as increased motility in mammary cell lines. Based on sequence analysis...
8674059 Colon cancer related gene TOM34  
Objective methods for detecting and diagnosing colon cancer are described herein. In one embodiment, the diagnostic method involves determining the expression level of TOM34 that discriminates...
8673980 Closthioamides, compositions, and methods for treating bacterial or fungal infections or cancer  
This invention relates to the field of biologically active compounds and specifically to closthioamides, pharmaceutical compositions comprising these compounds, and their use as antibiotic,...
8673972 Human papilloma virus as predictor of cancer prognosis  
Methods of treating a head and neck cancer are disclosed.
8673933 JAK2 inhibitors and their use for the treatment of myeloproliferative diseases and cancer  
The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of JAK2, thereby making them useful as...
8673910 Proteasome inhibitors for selectively inducing apoptosis in cancer cells  
The subject invention concerns compounds having activity as inhibitors of proteasomes and methods of using the subject compounds. In one embodiment, a compound of the invention has the chemical...
8673888 Depsipeptide for therapy of kidney cancer  
The present invention provides a therapeutic agent of kidney cancer, which comprises FK228 of the formula (I) or a salt thereof. FK228 or a salt thereof, which is an active ingredient in the...
8673874 Methods for treating pancreatic cancer  
The present invention provides a method of treating pancreatic cancer by inhibiting the activity cyclin D1 activity in tumor cells. The invention is based on the finding that cyclin D1 shRNA...
8673870 Combined DNA vaccine and biological modifiers for cancer therapy  
The present invention relates to the combination of a DNA vaccination strategy that makes use of a nucleic acid encoding an immunogenic polypeptide, with a non-immunosuppressive inducer of tumor...
8673573 Use of eIF3m for the diagnosis and treatment of cancer  
Disclosed are a cancer marker-detecting composition comprising an agent for measuring an mRNA or protein expression level of eIF3m, a cancer diagnosis kit comprising the same, a method for...
8673358 Nano-carrier, complex of anticancer drug and nano-carrier, pharmaceutical composition thereof, method for manufacturing the complex, and method for treating cancer by using the pharmaceutical composition  
The present invention relates to a nano-carrier for an anticancer drug, which comprises: a metal nanoparticle; and a polynucleotide for connecting with an anticancer drug having a pyrimidine group...
8673343 Preparation and administration of jojoba product for reducing weight, fat and blood lipid levels and for the prevention and treatment of cancer  
A method of orally administering jojoba for fat reduction, blood lipid reduction, and cancer prevention and treatment in humans is disclosed. The method incorporates a sufficient quantity of...
8673302 Anti-cMet antibody and its use for the detection and the diagnosis of cancer  
The present invention relates to the field of prognosis and/or diagnosis of a proliferative disease in a patient. More particularly, the invention relates to antibodies capable of binding to the...
8673003 Method for improving the early detection of breast cancer and device therefor  
A device for improving the early detection of a malignant breast cancer tumor in the breast of a human being includes a foreign body implant which is shaped and dimensioned to imitate a breast...
8669243 Steroid-derived cyclopamine analogs and methods for using the same in the prevention or treatment of cancer  
The present invention relates to steroid-derived cyclopamine analogs and methods for using the same for inhibiting sonic hedgehog signaling and preventing or treating cancer. A method for...
8669067 Cancer biomarker and the use thereof  
Gastric cancer is one of the leading causes of cancer-related death worldwide. To date no specific marker is available for gastric cancer screening. The expression profile of 37 proteins was...
8669063 Methods of using biomarkers for predicting the outcome of an immunotherapy against cancer  
The present invention relates to methods for predicting the effect of an immunotherapy against cancer in a patient based on new biomarkers. The present invention furthermore relates to a prognosis...
8669058 Method of profiling gene expression in a subject having colorectal cancer  
The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and...
8669054 Marker for gastric cancer and method for detecting gastric cancer  
In embodiments the expression or methylation of the PAX5 gene is used as a marker for the diagnosis and prognosis of gastric cancer. In further embodiments methods for detecting gastric cancer are...