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8604169 Nucleic acids and corresponding proteins entitled 251P5G2 useful in treatment and detection of cancer  
A novel gene 251P5G2 and its encoded protein, and variants thereof, are described wherein 251P5G2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the...
8604067 ITE for cancer intervention and eradication  
A method of cancer intervention or eradication by administering an effective amount of an endogenous ligand for the aryl hydrocarbon (Ah) receptor (AhR) named ITE or one of its analogs (the active...
8604023 1,4-benzodiazepinone compounds and their use in treating cancer  
The invention provides a family of 1,4-benzodiazepinone compounds and methods for their use as therapeutic agents in treating cancer. Pharmaceutical compositions and methods of making the...
8603991 Individualized cancer therapy  
Methods for treating cancer that include (a) obtaining a specimen of cancer issue from a patient; (b) obtaining a specimen of normal tissue in the proximity of the cancer tissue; (c) extracting...
8603985 Treatment or prevention of cancer and precancerous disorders  
The NSAID, sulindac and/or its metabolites and derivatives, in combination with hydrogen peroxide or another oxidizing agent, such as arsenic trioxide that generates reactive oxygen species (ROS),...
8603764 EphA kinase cancer diagnostic  
A method of detecting malignant progression of neoplastic cells in an animal includes obtaining a sample of neoplastic cells from the animal, determining a level of S897-EphA2 phosphorylation in...
8603763 Functional immunohistochemical cell cycle analysis as a prognostic indicator for cancer  
The present invention relates to a method of determining the presence of a retinoblastoma protein (Rb)-mediated cancerous or pre-cancerous condition in a sample of fixed cells that involves...
8603747 Method and system for automated image analysis in cancer cells  
A method of screening for the presence and/or extent of a pathology in a subject, the pathology characterized by an abnormal chromosomal component in a cell of the subject, comprising the steps of:...
8603744 Methods for diagnosing breast cancer using MicroRNAs  
The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis.
8603734 Biomarkers for prostate cancer  
The instant invention provides methods and compositions for the detection of prostate cancer is a subject. In one embodiment, a method of detecting prostate cancer in a subject comprises the steps...
8603501 Cancer cell targeting using nanoparticles  
The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of...
8603500 Cancer cell targeting using nanoparticles  
The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of...
8603499 Cancer cell targeting using nanoparticles  
The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of...
8603482 Compositions and methods for cancer immunotherapy  
The invention relates to immunotherapeutic compounds and to methods for stimulating an immune response in a subject individual at risk for developing cancer, diagnosed with a cancer, in treatment...
8603474 Membrane transporter NaPi2b (SCL34A1) epitope for antibody therapy, antibodies directed thereto, and target for cancer therapy  
The present disclosure relates generally to the membrane transporter NaPi2b (SLC34A2) as a target for therapy, including immunotherapy, and particularly cancer therapy. The SLC34A2 epitope peptide...
8603469 Methods of treating cancer with human monoclonal antibodies against interleukin 8  
Isolated human monoclonal antibodies which bind to IL-8 (e.g., human IL-8) are disclosed. The human antibodies can be produced in a hybridoma, transfectoma or in a non-human transgenic animal,...
8600003 Compact microbeam radiation therapy systems and methods for cancer treatment and research  
The present subject matter relates to compact, non-synchrotron microbeam radiation therapy (MRT) systems and methods for cancer research and treatment based on a carbon nanotube distributed x-ray...
8598543 Multi-axis/multi-field charged particle cancer therapy method and apparatus  
The invention relates to a method and apparatus for treatment of solid cancer. More particularly, the invention comprises a multi-axis and/or multi-field raster beam charged particle cancer therapy...
8598408 Method of producing an antibody using a cancer cell  
The present invention aims to provide a method for antibody preparation. The present invention is directed to a method for preparing an antibody-producing cell, which comprises the following steps:...
8598333 SiRNA silencing of genes expressed in cancer  
The present invention provides nucleic acid-lipid particles comprising siRNA molecules that silence genes expressed in cancer (e.g., Eg5, EGFR or XIAP) and methods of using such nucleic acid-lipid...
8598188 Method for predicting therapeutic efficacy of chemotherapy on non-small-cell lung cancer  
This invention relates to an antitumor agent comprising carboplatin and a combination drug of tegafur/gimeracil/oteracil potassium to be administered to a cancer patient selected according to an...
8598145 Mitochondrially delivered anti-cancer compounds  
This invention relates to anti-cancer compounds and to methods for treating or preventing cancer. In one aspect the invention concerns mitochondrially delivered pro-oxidant anti-cancer compounds...
8598135 Insulin-like growth factor binding protein 7 for treatment of cancer  
Methods of treating a tumor in a subject include identifying a subject having, at risk for, or suspected of having a tumor, and administering to the subject an effective amount of an IGFBP7 agent...
8597953 Volatile organic compounds as diagnostic markers in the breath for lung cancer  
A set of volatile organic compounds is provided, comprising at least butylated hydroxy toluene or 4,6-di (1,1-dimethylethyl)-2-methyl-phenol for breath analysis. Methods of use thereof in...
8597946 Enhanced dendritic cells for cancer immunotherapy  
Described herein are methods of cancer immunotherapy, particularly methods of preparing a population of enhanced dendritic cells and methods of treating cancer using the enhanced dendritic cells.
8597900 Compositions and methods for the treatment of cancer  
Disclosed herein are methods and compositions for the treatment of cancer. In particular, the present invention discloses inhibitors of the Fanconi anemia pathway and methods using same. Such...
8597889 Method for detecting cancer cell caused by HPV, method for determining whether or not tissue is at stage of high-grade dysplasia or more severe stage, and primer set and kit used therefor  
Provided are a primer set, a method and a kit therefor, which can easily perform with high accuracy the detection of a cancer cell caused by HPV and the determination of whether or not a tissue is...
8597883 Biomarkers for cancer-related fatigue and use thereof  
Described herein is the identification of genes that are significantly up- or down-regulated in patients suffering from cancer-related fatigue (CRF), providing a means for the diagnosis and...
8597645 Cancer treatment with endothelin receptor antagonists  
The present invention relates to therapeutic protocols and pharmaceutical compositions designed to treat and prevent cancer. More specifically, the present invention relates to a novel method of...
8597637 Breast cancer therapy using an engineered respiratory syncytial virus  
The invention discloses an engineered oncolytic respiratory syncytial virus (RSV), NS1 gene deficient RSV, and its usage to treat breast cancer by killing cancer cells with in vitro and in vivo...
8592589 Methods of treating cancer with a thieno[3,2-C]pyridine  
N-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3 ,2-c]pyridin-3-yl}phenyl)-N′-(3-fluorophenyl)urea free base and crystallines form thereof are suitable pharmaceutical ingredients for p...
8592465 Compounds for treatment of cancer  
Compounds according to formula (I) are disclosed where Q is S, N, or O; X is optional, and can be O═, S═, ═N—NH2, ═N—OH, or —OH; Y is optional and can be —N(H)—, O, or C1 to C20 hydrocarbon; and ...
8592173 Cancer diagnosis by measuring polyisoprenylated methylated protein methyl esterase activity  
Methods for cancer diagnosis, making decisions on appropriate cancer treatment, awareness of a predisposition to cancer and potential cancer prevention, and monitoring of cancer therapy by...
8592168 Methods for diagnosing and treating neuroendocrine cancer  
The present invention relates to a method for diagnosing neuroendocrine cancers via detecting the presence of N-methyl D-asparate-associated (NMDA) glutamate receptors type 1 and/or type 2. Methods...
8592152 Gene detection assay for improving the likelihood of an effective response to an EGFR antagonist cancer therapy  
The invention provides a method for more effective treatment of patients susceptible to or diagnosed with tumors overexpressing EGFR, as determined by a gene amplification assay, with an EGFR...
8592147 High-content screening for drugs against cancer and age-related diseases  
The invention relates to methods for high-throughput screening for compounds that modulate cell growth or promoter activity. The invention provides the use of cell lines with properly regulated...
8592145 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Cancer marker, method for evaluation of cancer by using the cancer marker, and evaluation reagent
 
The present invention provides a novel cancer marker for evaluating the onset, the preclinical stage, the clinical stage, or the prognosis of a cancer in a subject, and an evaluation method using...
8591921 Induction of tumor hypoxia for cancer therapy  
Methods and compositions for enhancing the ability of hypoxia-activated bioreductive agents to kill tumor cells within solid tumors are provided. Local regions of hypoxia are created within a...
8591892 FTY720 increases CD74 expression and sensitizes cancer cells to anti-CD74 antibody-mediated cell death  
Disclosed herein are methods and compositions comprising fingolimod and anti-CD74 antibodies or fragments thereof. In preferred embodiments, the fingolimod increases the expression of CD74 in...
8591887 EPHA2 as a therapeutic target for cancer  
The present invention is directed to compounds and methods for the treatment of metastatic disease. The compounds of this invention have specificity for EphA2, an epithelial cell tyrosine kinase...
8591863 Compositions against cancer antigen LIV-1 and uses thereof  
Described herein are methods and compositions that can be used for diagnosis and treatment of cancer.
8586754 BCL-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases  
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 or Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which are expressed...
8586749 Compounds that suppress cancer cells and exhibit antitumor activity  
The present invention provides compounds S3I-201.1066 (Formula 1) and S3I-201.2096 (Formula 2) as selective Stat3 binding agents that block Stat3 association with cognate receptor pTyr motifs,...
8586557 Therapy of p53 mutant colon adenocarcinoma, breast cancer and lung cancer  
The present invention provides a method for treating a hyperproliferative disorder characterized by expression of a mutant form of p53 in a subject, the method comprising administering to the...
8586553 Therapies for cancer using RLIP76  
The present invention is a composition identified as a region of ralA binding protein 1, wherein the region neighbors a membrane-associated portion of the ralA binding protein 1, reduces transport...
8586544 Cell-permeable endostatin recombinant protein, a polynucleotide encoding the same, and an anti-cancer preparation containing the same as an active component  
The present invention relates to a cell-permeable endostatin recombinant protein in which a macromolecule transduction domain (MTD) is fused to an angiogenesis inhibitor (angiogenesis inhibitor)...
8586543 IL-8 biomarker for monitoring cancer treatment with certain ERK inhibitors  
The present application includes methods for using IL-8 as a biomarker for, e.g., tumor size, for example, during course of treatment with an anti-cancer agent such as an ERK inhibitor.
8586380 Monitoring treatment of head and neck cancer patients with drugs targeting EGFR pathway using mass spectrometry of patient samples  
Methods using mass spectral data analysis and a classification algorithm provide an ability to determine whether a non-small-cell lung cancer patient, head and neck squamous cell carcinoma or...
8586379 Monitoring treatment of colorectal cancer patients with drugs targeting EGFR pathway using mass spectrometry of patient samples  
Methods using mass spectral data analysis and a classification algorithm provide an ability to determine whether a non-small-cell lung cancer patient, head and neck squamous cell carcinoma or...
8586313 DNA methylation markers based on epigenetic stem cell signatures in cancer  
In particular aspects, stem-cell polycomb group (PcG) targets are more likely to have cancer-specific promoter DNA methylation than non-targets, indicating a stem-cell origin of cancer, where...