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US20120130922 |
Method and Apparatus for Processing Financial Information at Hardware Speeds Using FPGA Devices
A method and apparatus use hardware logic deployed on a reconfigurable logic device to process a stream of financial information at hardware speeds. The hardware logic can be configured to perform...
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US20120128590 |
NANOPARTICLE DELIVERY SYSTEMS FOR MEMBRANE-INTEGRATING PEPTIDES
Compositions which comprise emulsions of nanoparticles for delivery of membrane-integrating peptides are described. The nanoparticles comprise a liquid hydrophobic core coated with a...
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US20120116998 |
Method and Apparatus for Processing Financial Information at Hardware Speeds Using FPGA Devices
A method and apparatus use a reconfigurable logic device to process a stream of financial information at hardware speeds. The reconfigurable logic device can be configured to perform data...
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US20120115747 |
Methods Of Renal Cancer Detection
Disclosed are methods for detecting, diagnosing or monitoring a renal cancer in a subject. The methods include detecting quantity of one or more polypeptides or fragments thereof comprised by body...
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8175702 |
Method for low-voltage termination of cardiac arrhythmias by effectively unpinning anatomical reentries
A method for extinguishing a cardiac arrhythmia utilizes destructive interference of the passing of the reentry wave tip of an anatomical reentry through a depolarized region created by a...
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US20120110316 |
Intelligent Data Storage and Processing Using FPGA Devices
A re-configurable logic device such as a field programmable gate array (FPGA) can be used to deploy a data processing pipeline, the pipeline comprising a plurality of pipelined data processing...
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US20120109849 |
Intelligent Data Storage and Processing Using FPGA Devices
A re-configurable logic device such as a field programmable gate array (FPGA) can be used to deploy a data processing pipeline, the pipeline comprising a plurality of pipelined data processing...
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8168650 |
Therapeutic uses of bicyclic ligands of sigma 2 receptor
A series of N-substituted 9-azabicyclo[3.3.1]nonan-3α-yl phenylcarbamate analogs are disclosed, as well as methods of their preparation. Their affinities for sigma (σ1 and σ2) receptors are de...
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US20120100186 |
NANOPARTICULATE-BASED CONTRACEPTIVE/ANTI-HIV COMPOSITION AND METHODS
Nanoparticulate compositions which employ membrane-integrating peptides to effect contraception and/or protection against infection by sexually transmitted virus are described.
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US20120100073 |
PET RADIOTRACERS FOR IMAGING FATTY ACID METABOLISM AND STORAGE
Fatty acid analogue (FAA) molecules comprising positron-emitting radionuclides, salts thereof, and FAA-triglycerides are disclosed. Also disclosed are methods of synthesis, and methods of imaging...
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8153156 |
Hydrogel nanocompsites for ophthalmic applications
The present invention relates to reversible hydrogel systems. Particularly, the hydrogel of the present invention is made up of copolymers that can be a hydrogel when in an oxidize state and can be...
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8148097 |
Screening method for identification of compounds with calcium-independent phospholipase A2β (iPLA2β) modulating activity
An in vitro screening method for identifying a compound with iPLA2β modulating activity.
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US20120077682 |
COMPOSITIONS AND METHODS FOR DETECTING CANCER METASTASIS
The present invention encompasses compositions and methods for detecting cancer metastasis.
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US20120076758 |
ANTIBODIES AGAINST WEST NILE VIRUS AND THERAPEUTIC AND PROPHYLACTIC USES THEREOF
The present invention relates to compositions comprising antibodies or fragments thereof that immunospecifically bind to one or more antigens of a flavivirus, particularly of West Nile Virus (WNV),...
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8143222 |
Modular platform for targeted therapeutic delivery
Pharmaceutical compounds, pharmaceutical compositions and methods of treatment are disclosed, wherein a compound comprises a targeting moiety which, in free form, binds a cell receptor with a...
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US20120068084 |
RADIATION DOSIMETERS FOR QUANTIFYING THE DOSE OF RADIATION APPLIED DURING RADIATION THERAPY
Radiation dosimeters containing thin KCl:Eu2+ storage phosphors for quantifying and/or verifying the dose of radiation applied during radiation therapy. Methods for measuring the amount of...
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8133685 |
AMPK modulation as a method of regulating stem cell and cancer stem cell proliferation, self-renewal and differentiation
Methods are disclosed for decreasing stem cell proliferation, including cancer stem cell proliferation. These methods comprise administering to stem cells inhibitors of AMP activated protein kinase...
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8133493 |
Regulated attenuation of live vaccines to enhance cross-protective immunogenicity
A live attenuated derivative of a pathogenic bacterium intended for use as a vaccine.
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US20120059308 |
PERIPHERAL NERVE BLOCK CATHETER
An anesthetic nerve block catheter and methods of using the anesthetic nerve block catheter to perform a nerve block or continuous nerve block procedure are disclosed.
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8131697 |
Method and apparatus for approximate matching where programmable logic is used to process data being written to a mass storage medium and process data being read from a mass storage medium
A method and device are disclosed for an associative and approximate, analog or digital scanning of databases that allows for the asynchronous accessing of data from a mass storage medium. The...
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US20120041303 |
PHAGE ANTIBODIES TO RADIATION-INDUCIBLE NEOANTIGENS
A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. The method includes the steps of: (a) exposing a tumor to ionizing radiation; (b)...
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US20120040360 |
COMPOSITIONS, METHODS AND KITS TO DETECT DICER GENE MUTATIONS
In one aspect, the disclosure provides isolated nucleic acids, polypeptides, primers, and probes for the detection of mutations in a nucleic acid sequence for a DICER1 polypeptide.
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US20120040357 |
COMPOSITIONS, METHODS AND KITS TO DETECT DICER GENE MUTATIONS
In one aspect, the disclosure provides isolated nucleic acids, primers, and probes for the detection of mutations in a nucleic acid sequence for a DICER1 polypeptide.
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US20120035359 |
PHENOXAZINE DERIVATIVES AND METHODS OF USE THEREOF
The present invention encompasses phenoxazine derivatives and methods of use thereof.
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US20120034550 |
Palladium-Platinum Nanostructures And Methods For Their Preparation
Palladium-seeded, dendritic platinum nanostructures that are useful as electrocatalysts and methods for preparing such nanostructures. The palladium-platinum nanostructures may be incorporated into...
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US20120028793 |
DUAL-OXIDE SINTER RESISTANT CATALYST
A catalyst material for use at elevated temperatures is provided. The material can include a plurality of fibers and a plurality of particles supported on the fibers. In addition, a porous layer...
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US20120022392 |
Correlating Frequency Signatures To Cognitive Processes
Determining an intended action based on one more brain signal frequencies includes establishing communication with one or more electrodes for sensing brain signals of a subject, and acquiring the...
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US20120022391 |
Multimodal Brain Computer Interface
Determining an intended action based on one more cortico-physiologies within brain signals includes establishing communication with one or more electrodes for sensing the brain signals of a...
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US20120021534 |
MARKERS FOR BRAIN DAMAGE
Methods to identify markers for brain damage using fresh brain tissue and methods and compositions for detecting these markers are disclosed.
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8101606 |
Neurofibromin pathway modulators
The present invention encompasses methods for treating neurofibromatosis.
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US20120015990 |
TASPASE1 INHIBITORS AND THEIR USES
Provided herein are small molecule inhibitors of Taspase1 and methods of using the small molecule inhibitors of Taspase1 to treat neoplasm in subjects in need thereof.
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8095508 |
Intelligent data storage and processing using FPGA devices
A data storage and retrieval device and method is disclosed. The device includes at least one magnetic storage medium configured to store target data and at least one re-configurable logic device...
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8084374 |
Tuning of photo-absorption materials through use of magnetic fields
The disclosure relates to using magnetic fields for the purposes of modifying the absorption characteristics of materials, such as semiconductor materials, to both tune the materials to specific...
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US20110312919 |
INHIBITORS OF TYROSINE KINASE RECEPTOR DIMERIZATION
The teachings relate to methods of identifying inhibitors of dimerization of tyrosine receptor kinases such as EGFR. The methods comprise providing, on a digital computer, a molecular model...
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US20110311519 |
METHODS OF TREATMENT OF BONE DEGENERATIVE DISEASES
Methods of reducing bone loss and treating degenerative bone diseases such as osteoporosis are disclosed. The methods comprise administration of an agent that inhibits signaling through the IL-17...
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US20110311447 |
Compounds comprising 4-benzoylpiperidine as a Sigma-1-selective ligand
Bipiperidinyl compounds and salts thereof are disclosed. The compounds include high affinity ligands for σ1 receptors. Some compounds are also highly selective for σ1 receptor compared to σ2 re...
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8080371 |
Markers for addiction
Correlations between polymorphisms and addiction are provided. Methods of diagnosing, prognosing, and treating addiction are provided. Systems and kits for diagnosis, prognosis and treatment of...
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US20110300629 |
TRAIL trimers, methods and uses therefor
Disclosed are TNF-related apoptosis-inducing ligand (TRAIL) trimers (TR3) and nucleic acids encoding covalently linked TRAIL trimers. A TRAIL trimer can have greater stability compared to native...
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US20110300071 |
TARGETING NPR-C IN ANGIOGENESIS AND ATHEROSCLEROSIS WITH A C-TYPE ATRIAL NATRIURETIC FACTOR (CANF)-COMB NANOCOMPLEX
Tracers are disclosed comprising an amphiphilic comb-like nanostructure conjugated with an oligopeptide such as a fragment of a natriuretic peptide, and a signaling moiety such as a...
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8071838 |
Targeted and regional cellular ablation in zebrafish
A system including: (i) a methodology for targeted cellular ablation in zebrafish; (ii) a methodology for regional cellular ablation in zebrafish. These methodologies are used to identify genetic...
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8071381 |
Systems and methods for screening pharmaceutical chemicals
A method for obtaining a response of a tissue model system to an activator includes contacting a bio-artificial tissue model system with an activator and measuring cellular mechanical response...
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US20110295143 |
BRAIN FUNCTION MAPPING
A method for identifying a functional area of a brain. The functional area is associated with a neurological function. The method includes applying a plurality of electrodes to a surface of the...
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US20110294138 |
METHODS FOR SIMULTANEOUSLY MEASURING THE IN VIVO METABOLISM OF TWO OR MORE ISOFORMS OF A BIOMOLECULE
The present invention encompasses methods for the simultaneous measurement of the in vivo metabolism of two or more isoforms of a biomolecule. The biomolecule is typically produced in the central...
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8069102 |
Method and apparatus for processing financial information at hardware speeds using FPGA devices
A method and apparatus use decision logic deployed on a reconfigurable logic device to process a stream of financial information at hardware speeds. The decision logic can be configured to perform...
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8063268 |
Transposable elements in rice and methods of use
Disclosed are isolated transposable elements, or isolated DNA sequences which encode a transposase protein or a portion of a transposase protein. The isolated transposable elements or the isolated...
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US20110282432 |
Vascular Graft With Lateral Opening
A vascular graft includes a flexible conduit including a sidewall defining a cavity extending between a first end and a second end. The first end includes an opening that is oriented substantially...
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US20110282183 |
Diagnosis Of Central Nervous System White Matter Pathology Using Diffusion MRI
Determining diffusivity of multiple diffusion components within a tissue using diffusion magnetic resonance data representing a volume of the tissue. A plurality of candidate fibers having a...
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US20110275890 |
MINIATURIZED PHOTOACOUSTIC IMAGING APPARATUS INCLUDING A ROTATABLE REFLECTOR
A reflection-mode photoacoustic endoscope includes a light source configured to emit a light pulse, a signal detection or transmission unit configured to detect or emit an ultrasonic pulse, and a...
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8053415 |
Compounds having RD targeting motifs
The present invention provides compounds that have motifs that target the compounds to cells that express integrins. In particular, the compounds have peptides with one or more RD motifs conjugated...
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8046044 |
Method and apparatus for acquiring overlapped medical image slices
The disclosure describes a technique for medical imaging, referred to herein as the Rapid Interleave Overlap Technique (RIOT), wherein image data is acquired as a plurality of series sequences in a...
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