Patents and Patent Applications from Wake Forest University


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8178303 Increasing the speed of cryoglobulin precipitation  
The present invention provides a method for the precipitation of cryoglobulins. In general, the method comprises the steps of: (a) providing a cryoglobulin sample; (b) providing a reagent such as a...
8145292 Method and system for producing interactive, three-dimensional renderings of selected body organs having hollow lumens to enable simulated movement through the lumen  
A method and system are provided for effecting interactive, three-dimensional renderings of selected body organs for purposes of medical observation and diagnosis. A series of CT images of the...
8138200 Compositions and methods for double-targeting virus infections and targeting cancer cells  
The invention includes compositions and methods useful for treatment of a virus infection in a mammal by double-targeting the virus (i.e. targeting the virus at more than one stage of the virus...
8128406 Predictive assessment of reading  
Methods and systems for predicting future and concurrent reading ability are provided. A first variable comprising a measurement of picture vocabulary, a second variable comprising a measurement of...
8109035 Apparatus and method of mosquito control  
A mosquito control trap taking advantage of the normal stages of development for a mosquito. The trap including stagnant water trapped within a container by a weeping platform floating on top of...
8106032 Lipid analogs for combating tumors  
The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an...
8103073 Cardiac visualization systems for displaying 3-D images of cardiac voxel intensity distributions with optional physician interactive boundary tracing tools  
Physician interactive workstations with global cardiac voxel distribution visualization may also include one or more of a 3-D color scale image of a population of voxel in the heart and/or an...
US20110287975 Methods and Compositions for Correlating Genetic Markers with Conversion of Medium Chain Polyunsaturated Fatty Acids to Long Chain Polyunsaturated Fatty Acids  
The present invention provides methods of identifying a subject having an increased or decreased ability to convert medium chain-polyunsaturated fatty acids (MC-PUFAs) to long chain polyunsaturated...
8042167 Methods, systems, and computer program products for network firewall policy optimization  
Methods, systems, and computer program products for firewall policy optimization are disclosed. According to one method, a firewall policy including an ordered list of firewall rules is defined....
8037517 Method, systems, and computer program products for implementing function-parallel network firewall  
Methods, systems, and computer program products for providing function-parallel firewalls are disclosed. According to one aspect, a function-parallel firewall includes a first firewall node for...
8034781 Angiotensin-(1-7) and angiotensin-(1-7) agonists for inhibition of cancer cell growth  
The present invention describes the use of angiotensin-(1-7) peptide as an anti-cancer therapeutic. Thus, in one embodiment, the present invention comprises a composition to inhibit the growth of...
8021830 Method for increasing plasma volume by administering a plasma expander comprising basic alpha keratose  
A liquid plasma expander or resuscitation fluid composition for use in a subject in need thereof, comprising, consisting of; or consisting essentially of: (a) a keratin derivative (preferably alpha...
7995823 Image reporting method and system  
A method and system are provided to report the findings of an expert's analysis of image data. The method and system are based on a reporting system that forms the basis of an image management...
7993843 Genetic polymorphisms in the prostate-specific antigen gene promoter  
The present invention includes methods of identifying a subject at risk for increased cellular PSA production and/or prostate cancer by detecting the presence or absence of a genetic polymorphism...
7989652 C-nitroso-derived nitroxyl donors  
Active compounds of Formula I are described: wherein: R1 and R2 are each independently C1-C4 alkyl; or R1 and R2 together form a C2-C7 alkylene chain; and Z is a non-steroidal anti-inflammatory...
US20110097379 DIRECTED STEM CELL RECRUITMENT  
The invention is directed to methods of inducing cell recruitment and tissue regeneration at a target site in a subject. It is also based, in part, on the discovery that a subject's own biologic...
7927864 Methods, kits, and compositions for detecting enzyme activity  
The inventive subject matter relates to methods, kits, and compositions for detecting enzyme activity in a biological sample. In particular, the inventive subject matter relates to methods, kits,...
7907759 Cardiac visualization systems for displaying 3-D images of cardiac voxel intensity distributions with optional physician interactive boundary tracing tools  
Physician interactive workstations with global cardiac voxel distribution visualization may also include one or more of a 3-D color scale image of a population of voxel in the heart and/or an...
7892573 Nerve regeneration employing keratin biomaterials  
A keratin hydrogel matrix serves as an effective acellular scaffold for axonal regeneration and facilitates functional nerve recovery.
7883847 Transcriptional profiling of stem cells and their multilineage differentiation  
The present invention concerns methods of screening cells for differentiation or de-differentiation, and/or for status as a pluripotent or multipotent (e.g., “stem”) cell, by detecting the dif...
US20100323029 FIVE-COORDINATE NEUROGLOBIN AND USE THEREOF AS A BLOOD SUBSTITUTE  
Described herein is the finding that a mutant form of human neuroglobin (H64L) with a stable five-coordinate geometry reduces nitrite to nitric oxide approximately 2000-times faster than the wild...
7853310 Automatic analysis in virtual endoscopy  
A computer system and a computer-implemented method are provided for interactively displaying a three-dimensional rendering of a structure having a lumen and for indicating regions of abnormal wall...
7835560 Image reporting method and system  
A method and system are provided to report the findings of an expert's analysis of image data. The method and system are based on a reporting system that forms the basis of an image management...
US20100285489 METHOD FOR DIAGNOSING RENAL DISEASES OR PREDISPOSITIONS  
The invention provides a method of diagnosing a disease or a predisposition to contract a disease by assaying for mutations of uromodulin (UMOD) within a test subject or patient. The presence of a...
US20100285048 USE OF FLAGELLIN IN THE IMMUNOTHERAPY OF YERSINIA PESTIS  
The invention provides a fusion protein comprising a flagellin adjuvant and a Yersinia pestis antigen. Also provided are compositions comprising a flagellin adjuvant and a Yersinia pestis antigen....
7829108 Structurally modified acellular tissue engineering scaffolds and methods of production  
Methods are provided for producing a bioscaffold from natural tissues by oxidizing a decellularized tissue to produce a bioscaffold having pores therein. The pore size and porosity is increased to...
7818043 Cardiac diagnostics using wall motion and perfusion cardiac MRI imaging and systems for cardiac diagnostics  
Cardiac information of a patient is displayed by obtaining a plurality of MRI cine loops of the heart of the patient at a plurality of heart rates, the plurality of cine loops including both wall...
US20100247682 USE OF NITRITE SALTS FOR THE TREATMENT OF CARDIOVASCULAR CONDITIONS  
It has been surprisingly discovered that administration of nitrite to subjects causes a reduction in blood pressure and an increase in blood flow to tissues. The effect is particularly beneficial,...
7803630 Method for detecting target compounds containing sulfenic acids using new reagents  
The present invention provides compounds of Formula I: wherein: R1 is a label (e.g., a detectable groups; an anti-tumor agent)s; L is present or absent and when present is a linking group; and x...
7801587 Method and system for creating three-dimensional images using tomosynthetic computed tomography  
A system for constructing image slices through a selected object, the system comprising an identifiable fiducial reference in a fixed position relative to the selected object, wherein the fiducial...
7794731 Use of flagellin in the immunotherapy of Yersinia pestis  
The invention provides a fusion protein comprising a flagellin adjuvant and a Yersinia pestis antigen. Also provided are compositions comprising a flagellin adjuvant and a Yersinia pestis antigen....
7792565 Method and system for producing interactive, three-dimensional renderings of selected body organs having hollow lumens to enable simulated movement through the lumen  
A method and system are provided for effecting interactive, three-dimensional renderings of selected body organs for purposes of medical observation and diagnosis. A series of CT images of the...
US20100216142 MICRORNA BIOMARKERS IN LUPUS  
The present invention provides methods of screening a subject for systemic lupus erythematosus (SLE), comprising detecting an increase in an amount of one or more markers associated with SLE in a...
7781164 Method for diagnosing renal diseases or predispositions  
The invention provides a method of diagnosing a disease or a predisposition to contract a disease by assaying for mutations of uromodulin (UMOD) within a test subject or patient. The presence of a...
US20100204322 METHOD OF TREATING AUTOIMMUNE DISEASES  
A method of treating an autoimmune disease (for example, Systemic Lupus Erythematosus) comprises administering to the subject a treatment effective amount of a histone hyperacetylating agent, or a...
US20100185121 Small-Scale Pressure Sensors  
The present invention provides a method of sensing pressure in a region of interest by providing a plurality of metallic particles operatively associated with one another in the region of interest...
US20100173006 METHODS OF RESTORATION OF ERECTILE FUNCTION  
A method for ameliorating erectile dysfunction (ED) in a subject, by injecting a population of cells capable of increasing nitric oxide production in corporal tissue, and maintaining the cells in...
7749752 Compositions and methods for identifying antigens which elicit an immune response  
This invention relates to an expression vector wherein said expression vector comprises a polynucleotide promoter sequence, a polynucleotide encoding a signal sequence, a polynucleotide encoding an...
7747308 Non-invasive systems and methods for the determination of cardiac injury using a characterizing portion of a voxel histogram  
Methods, systems and circuits predict cardiotoxicity induced cardiac injury prior to an irreversible state by electronically generating at least one histogram of mean intensities of voxels/pixels...
7747055 Virtual endoscopy with improved image segmentation and lesion detection  
A system, and computer implemented method are provided for interactively displaying three-dimensional structures. Three-dimensional volume data (34) is formed from a series of two-dimensional...
US20100158977 PROGENITOR CELLS FROM URINE AND METHODS FOR USING THE SAME  
Provided herein are urine progenitor cells and methods for producing a culture of urine progenitor cells from a urine sample. The cells may be selected based upon the use of a selective cell...
US20100129450 Electrospun Cell Matrices  
The invention is directed to compositions and methods for preparing electrospun matrices comprising at least one natural biological material component and at least one synthetic polymer material....
7718372 Genetic polymorphisms in the prostate-specific antigen gene promoter  
The present invention includes methods of identifying a subject at risk for increased cellular PSA production and/or prostate cancer by detecting the presence or absence of a genetic polymorphism...
7696373 C-nitroso-derived nitroxyl donors  
Active compounds of Formula (I) are described: wherein: R1 and R2 are each independently C1-C4 alkyl; or R1 and R2 together form a C2-C7 alkylene chain; and Z is a non-steroidal anti-inflammatory...
7694455 Apparatus and method of mosquito control  
A mosquito control trap taking advantage of the normal stages of development for a mosquito. The trap including stagnant water trapped within a container by a weeping platform floating on top of...
7693317 Image reporting method and system  
A method and system are provided to report the findings of an expert's analysis of image data. The method and system are based on a reporting system that forms the basis of an image management...
US20100010088 Compositions and Methods for Prevention and Treatment of Mammalian Diseases  
The present invention discloses processes of making a polyunsaturated fatty acid compositions, and compositions thereof. Thus, one method of making a polyunsaturated fatty acid compositions...
7638528 Compositions and methods for targeting cancer cells  
The invention includes compositions and methods useful for treatment of a virus infection in a mammal by double-targeting the virus (i.e. targeting the virus at more than one stage of the virus...
D603967 Surgical head support adapter  
US20090265005 BIOREACTOR SYSTEM AND METHOD OF ENHANCING FUNCTIONALITY OF MUSCLE CULTURED IN VITRO  
A method of producing organized skeletal muscle tissue from precursor muscle cells in vitro comprises: (a) providing precursor muscle cells on a support in a tissue media; then (b) cyclically...
Matches 1 - 50 out of 230 1 2 3 4 5 >