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US20120129194 |
Visible Detection of Microorganisms
Methods of detecting very low levels of targets, such as cells, are provided. In some embodiments, for example, the methods can detect bacteria present in a sample at concentrations less than 25...
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US20120127035 |
ELECTRICALLY SMALL, SOURCE DIRECTION RESOLVING ANTENNAS
An electrically small receiver system is provided. The receiver system includes a plurality of antennas and a signal processing circuit. The plurality of antennas includes a first antenna...
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8183038 |
Composition comprising recombinant nucleic acid encoding Sox2, Oct-4, Nanog and Lin28
The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The...
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8179843 |
Distributed scheduling method for multi-antenna wireless system
A channel allocation system for a beam-forming wireless network selects receivers to enroll in communication from a pool of candidate receivers, by off-loading a determination of the effects of...
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8178517 |
6-methylvitamin D3 analogs and their uses
This invention discloses 6-methylvitamin D3 analogs, and specifically 1α,25-dihydroxy-6-methylvitamin D3, and pharmaceutical uses therefor. This compound exhibits vitamin D receptor binding ...
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8178331 |
Recombinant yeast with improved ethanol tolerance and related methods of use
The present invention provides isolated Elo1 and Mig3 nucleic acid sequences capable of conferring increased ethanol tolerance on recombinant yeast and methods of using same in biofuel production,...
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US20120116007 |
PATTERNABLE POLYMER BLOCK BRUSH LAYERS
Provided are novel polymer brushes that may be used in underlying buffer or imaging layers for block copolymer lithography. The novel polymer brushes include X-A-b-B and X-A-b-C block copolymer...
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8175359 |
Iterative highly constrained image reconstruction method
An image reconstruction method includes reconstructing an initial composite image of a subject using a conventional reconstruction method. The initial composite image employs the best information...
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8173968 |
System and method for improved radiation dosimetry
A radiation dosimetry quality assurance system is disclosed that includes a three-dimensional (3D) phantom extending along a longitudinal axis to form an exterior surface and an interior volume and...
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8173167 |
Micelle composition of polymer and passenger drug
Hydrophobic drugs become more practical for treatments by being encapsulated in micelle compositions for increasing solubility. Micelle compositions may include an excipient tocopherol and/or...
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US20120106377 |
METHOD AND APPARATUS FOR PROVIDING A MEASUREMENT OF PERFORMANCE FOR A NETWORK
Performance for a network is measured by sending multi-objective probes on a path, receiving at least one of the multi-objective probes for the path, and determining performance measurements for at...
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8170315 |
Localized and highly constrained image reconstruction method
An image reconstruction method includes reconstructing a composite image of a subject using a conventional reconstruction method. The composite image employs the best information available...
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8168284 |
Fabrication of complex three-dimensional structures based on directed assembly of self-assembling materials on activated two-dimensional templates
Methods of fabricating complex three-dimensional structures on patterned substrates and related compositions are provided. The methods involve depositing on the substrate a block copolymer material...
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8168133 |
Device for performing a high throughput assay
A device and method is provided for performing a high throughput assay. The device includes a plate structure having a plate and a plurality of microfluidic structures positioned thereon. Each...
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8164082 |
Spin-bus for information transfer in quantum computing
A spin bus quantum computing architecture includes a spin bus formed of multiple strongly coupled and always on qubits that define a string of spin qubits. A plurality of information bearing qubits...
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8163900 |
Seven-membered heterocyclic carbenes and their metal complexes
Disclosed are carbenes of the general formula: and including salts thereof, and metal complexes thereof. The carbenes are useful in any reaction where carbenes and carbene-metal complexes are used....
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8163325 |
Cheese having reintroduced fine particles of cheese
Methods of making acid and rennet-based cheeses include processing a previous lot of milk to produce curds and whey from the previous lot of milk, and removing the whey from the curd. For cottage...
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US20120094946 |
GLYCOSYLATED CHLORAMBUCIL ANALOGS AND USES THEREOF
A library of glycosylated chlorambucil analogs which are useful as anti-tumor and/or anti-metastatic agents is disclosed. The glycosylated chlorambucil analogs have the general formula wherein...
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8158614 |
Therapeutic treatment of cancer and dysplasia of the cervix or vagina using estrogen antagonists
A method for treatment of cervical or vaginal cancer and their associated dysplasia, including the steps of identifying a human cervical or vaginal cancer and/or dysplasia patient, administering an...
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8158424 |
Primate pluripotent stem cells cultured in medium containing gamma-aminobutyric acid, pipecolic acid and lithium
Previous methods for culturing primate pluripotent stem cells have required either fibroblast feeder cells or a medium which was exposed to fibroblast feeder cells to maintain the stem cells in an...
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8158422 |
Erythroid cells producing adult-type β-hemoglobin generated from human embryonic stem cells
Methods and compositions of erythroid cells that produce adult β-hemoglobin, generated by culturing CD31+, CD31+/CD34+ or CD34+ cells from embryonic stem cells under serum-free culture conditions.
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8158371 |
Assay for antibodies to Mycobacterium paratuberculosis
A method of detecting an immune response to a paratuberculosis-specific antigen, comprising incubating a sample from a subject with the paratuberculosis-specific antigen and detecting the presence...
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8158117 |
Methods and compositions for phosphate binding
The present invention provides improved methods and compositions for therapeutically controlling and/or reducing serum phosphate levels in animals and mammalian patients. The methods comprise...
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US20120088276 |
METHOD FOR USING REF PROTEIN AS A TARGETED RECA-DEPENDENT NUCLEASE
Kits and a method for cleaving double-stranded DNA using Ref and RecA protein and variants thereof at a site having a DNA sequence homologous to the sequence on a single-stranded DNA targeting...
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8154001 |
Ion radiation therapy system with variable beam resolution
An ion radiation therapy machine provides a steerable beam for treating a tumor within the patient where the exposure spot of the beam is controlled in width and/or length to effect a flexible...
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8153698 |
Method for producing bio-fuel that integrates heat from carbon-carbon bond-forming reactions to drive biomass gasification reactions
A low-temperature catalytic process for converting biomass (preferably glycerol recovered from the fabrication of bio-diesel) to synthesis gas (i.e., H2/CO gas mixture) in an endothermic...
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8153424 |
Method of in vitro differentiation of neural stem cells, motor neurons and dopamine neurons from primate embryonic stem cells
A method of differentiating embryonic stem cells into ventral spinal progenitor cells is disclosed. In one embodiment, the invention comprises culturing a population of cells comprising a majority...
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8153383 |
Mycobacterial culture screening test for Mycobacterium avium complex bacteria
A method of antigen-capture assays that uses the detection of antigens secreted into liquid culture is provided. Also provided are antibodies to Mycobacterium avium complex-specific antigens, and...
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8152999 |
Membrane cascade-based separation
The present invention provides counter flow cascade separation systems useful to separate solute/solute pairs present in a solvent. The separation systems include a series of interconnected stages...
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8152784 |
Method for treating or preventing steroid-induced glaucoma
An integrin antagonist reduces the occurrence of cross-linked actin network (CLAN) structures in cells of the trabecular meshwork. CLAN structures are associated with steroid-induced glaucoma....
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US20120083614 |
(20R,25S)-2-Methylene-19,26-Dinor-1alpha,25-Dihydroxyvitamin D3 in Crystalline Form
A method of purifying (20R,25S)-2-methylene-19,26-dinor-1α,25-dihydroxyvitamin D3 to obtain (20R,25S)-2-methylene-19,26-dinor-1α,25-dihydroxyvitamin D3 in crystalline form. The method includes t...
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8150795 |
Methods and devices for analysis of clustered data, in particular action potentials (i.e. neuron firing signals in the brain)
Methods for clustering of multi-dimensional data allow unsupervised grouping of multi-dimensional data points into clusters having like characteristics. The methods may be usefully applied to...
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8149415 |
Background-free absorption spectroscopy using spectral differentiator
An absorption spectrometer provides improved rejection of background radiation signal by employing a frequency-swept laser signal without frequency dithering and performing an effective...
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8148984 |
Method for magnitude constrained phase contrast magnetic resonance imaging
A method for magnitude constrained phase contrast magnetic resonance imaging (MRI) is provided. The method utilizes an assumption that the image magnitude is shared across a series of images...
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8148553 |
Catalytic conversion of cellulose to liquid hydrocarbon fuels by progressive removal of oxygen to facilitate separation processes and achieve high selectivities
Described is a method to make liquid chemicals, such as functional intermediates, solvents, and liquid fuels from biomass-derived cellulose. The method is cascading; the product stream from an...
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US20120077738 |
COMPOSITIONS AND METHODS FOR PREDICTING HCV SUSCEPTIBILITY TO ANTIVIRAL AGENTS
Methods for determining the susceptibility of a hepatitis C virus (HCV) in a patient to anti-viral agents, particularly cyclophilin inhibitors such as cyclosporine A, are disclosed. The methods...
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US20120076498 |
HYBRID ANALOG-DIGITAL PHASED MIMO TRANSCEIVER SYSTEM
A transmitter supporting multiple-input, multiple-output communications is provided. The transmitter includes a signal processor, a plurality of feed elements, and an aperture. The signal processor...
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8144966 |
Use of endogenous fluorescence to identify invading metastatic breast tumor cells
The present invention broadly provides methods and systems for detecting, identifying, and characterizing conditions, including diseases and other disorders in human or other animal subjects, by...
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8143238 |
Methods of increasing epidermal skin thickness by topical administration of a 19-nor containing vitamin D compound
Methods of increasing the thickness of the epidermal layer in the skin of a human comprising topically administering a therapeutically effective dose of an active pharmaceutical ingredient...
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8142708 |
Micro fluidic system for single molecule imaging
Laminar flow of a carrier liquid and polymeric molecules through micro-channels is used to straighten the polymeric molecules and attach the straightened molecules to a wall of the micro-channel...
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US20120071562 |
2alpha-Methyl-19-Nor-(20S)-1alpha-Hydroxy-Bishomopregnacalciferol and Its Uses
This invention discloses 2α-methyl-19-nor-(20S)-vitamin D analogs, and specifically 2α-methyl-19-nor-(20S)-1α-hydroxy-bishomopregnacalciferol and pharmaceutical uses therefor. This compound ex...
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8140292 |
Method and system for controlling a voltage waveform
A method of automating a process for controlling a voltage waveform applied to an object is provided. A first waveform for applying to the object is received. A first FFT of the first waveform is...
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8137924 |
Method and compositions for detecting botulinum neurotoxin
A molecular construct capable of fluorescent resonance energy transfer (FRET), comprising a linker peptide, a donor fluorophore moiety and an acceptor fluorophore moiety, wherein the linker peptide...
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US20120065150 |
Neuroprotective effects of 2DG in Traumatic Brain Injury
This invention provides methods for reducing the extent and progression of traumatic brain injury and its deleterious sequellae specifically cognitive decline, post-traumatic epilepsy,...
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US20120064591 |
RECOMBINANT YEAST WITH IMPROVED ETHANOL TOLERANCE AND RELATED METHODS OF USE
The present invention provides isolated Elo1 and Mig3 nucleic acid sequences capable of conferring increased ethanol tolerance on recombinant yeast and methods of using same in biofuel production,...
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US20120064088 |
METHODS OF TREATING ANEURYSM
The present invention is directed to a method for treating aneurysms in vascular tissue. The method includes administering a bisphosphonate compound to a subject in an amount which is effective...
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8133732 |
Method of forming myeloid precursor cells from human embryonic stem cells
This invention relates to the culture of dendritic cells from human embryonic stem (ES) cells. Human ES cells are first cultured into hematopoietic cells by co-culture with stromal cells. The cells...
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8133731 |
Production of primate neural stem cells through expression of pax6
A transcription factor both necessary and sufficient for human neuroectoderm specification, Pax6, as well as applications thereof, is disclosed.
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8133680 |
Using liquid crystals to detect affinity microcontact printed biomolecules
The present invention provides methods, devices and kits for detecting a ligand. The methods involve capturing a ligand from a sample with an affinity substrate that includes a receptor for a...
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8133534 |
Methods and compositions for forming patterns with isolated or discrete features using block copolymer materials
Methods of directing the self assembly of block copolymers on chemically patterned surfaces to pattern discrete or isolated features needed for applications including patterning integrated circuit...
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