Patents and Patent Applications from WARF University of Wisconsin Madison


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US20170301432 STRETCHABLE TRANSMISSION LINES AND CIRCUITS FOR MICROWAVE AND MILLIMETER WAVE FREQUENCY WEARABLE ELECTRONICS  
Stretchable high frequency transmission lines and high-frequency filters comprising the transmission lines are provided. The transmission lines provide low power loss, even at microwave and...
US20170298534 THERMAL DIFFUSION DOPING OF DIAMOND  
Boron-doped diamond and methods for making it are provided. The doped diamond is made using an ultra-thin film of heavily boron-doped silicon as a dopant carrying material in a low temperature...
US20170298458 METHOD TO PRODUCE WATER-SOLUBLE SUGARS FROM BIOMASS USING SOLVENTS CONTAINING LACTONES  
A process to produce an aqueous solution of carbohydrates that contains C6-sugar-containing oligomers, C6 sugar monomers, C5-sugar-containing oligomers, C5 sugar monomers, or any combination...
US20170296558 USE OF 2AMD AND 2MD TO TREAT FIBROSIS  
The invention relates to using 2-methylene-19-nor-(20S)-1α,25-(OH)2D3 (2MD) or 2α-methyl-19-nor-(20S)-1α,25-(OH)2D3 (2AMD) to prevent nephrotoxicity and/or fibrosis in a patient, preferably...
US20170296490 USE OF LIGNIN-DERIVED ALDEHYDES AS ANTIFUNGAL AGENTS  
Described herein is a method and corresponding composition of matter for inhibiting the growth of fungi and oomycetes. The method includes contacting fungi or oomycetes with a growth inhibitory...
9790553 Biomarkers for human papilloma virus-associated cancers  
Cervical cancer cells and HPV+ head and neck cancer cells express three testis-specific genes not normally expressed in somatic cells: testicular cell adhesion molecule 1 (TCAM1), synaptonemal...
9790483 Reagents and methods for esterification  
Methods and reagents for esterification of biological molecules including proteins, polypeptides and peptides. Diazo compounds of formula I: where R is hydrogen, an alkyl, an alkenyl or an...
US20170290901 GLOBAL GENE REGULATORS (GGR) AS VACCINE CANDIDATES AGAINST PARATUBERCULOSIS  
Described herein is a mycobacterium mutant, comprising at least one mutation in at least one gene sequence encoding global gene regulators (GGRs) selected from the group consisting of sigH, sigL,...
US20170290852 MICELLE FORMULATIONS OF AMPHOTERICIN B  
The present technology relates generally to micelle formulations of amphotericin B that optionally include 5-fluorocytosine and methods of preparing such formulations. Methods of treating fungal...
9786853 Floating evaporative assembly of aligned carbon nanotubes  
High density films of semiconducting single-walled carbon nanotubes having a high degree of nanotube alignment are provided. Also provided are methods of making the films and field effect...
9783512 Bicyclic methylene aziridines and reactions thereof  
The oxidative functionalization of olefins is a common method for the formation of vicinal carbon-heteroatom bonds. However, oxidative methods to transform allenes into synthetic motifs containing...
9782118 Diagnosis of swallowing disorders using high resolution manometry  
Parameters extracted from high definition manometric measurements of the pharynx and upper esophagus at preidentified locations and times are applied to a supervised learning machine trained using...
US20170288586 VARIABLE MAGNETIZATION MACHINE CONTROLLER  
A variable magnetization machine control system comprising a controller configured to adjust a d-axis current waveform and a q-axis current waveform in accordance with an operating condition of a...
US20170285042 Gas-Phase Purification for Accurate Isobaric Tag-Based Quantification  
Described herein are mass spectrometry systems and methods which improve the accuracy of isobaric tag-based quantification by alleviating the pervasive problem of precursor interference and...
US20170283812 METHOD OF CREATING INDUSTRIAL STREPTOMYCES WITH CAPABILITY TO GROW ON CELLULOSIC POLYSACCHARIDE SUBSTRATES  
A heterologous gene cassette useful for creating Streptomyces species with enhanced capability of growing on a cellulosic polysaccharide substrate, wherein the cassette comprises at least two...
US20170283774 METHODS FOR EFFICIENT DERIVATION OF HUMAN MOTOR NEURONS FROM DIVERSE SPINAL REGIONS  
Described herein are chemically defined, adherent culture protocols for generating functional motor neurons characteristic of diverse hindbrain and spinal cord regions, with high efficiency.
US20170283772 METHODS FOR DIFFERENTIATION OF HUMAN PLURIPOTENT STEM CELLS TO BRAIN MICROVASCULAR ENDOTHELIAL CELLS  
Methods for generating functional brain microvascular endothelial cells (BMECs) under chemically defined, serum-free conditions are provided. In particular, efficient and cost-effective methods...
US20170283437 Inhibitors of UDP-Galactopyranose Mutase  
Compounds and salts thereof which inhibit microbial growth or attenuate the virulence of pathogenic microorganisms and which inhibit UDP-galactopyranose mutase (UGM). Compounds of the invention...
US20170281741 PEPTIDE AND METHOD FOR REDUCING THE PHOSPHATE REQUIREMENT AND EXCRETIION FROM FARM ANIMALS  
Disclosed are methods of altering metabolism of phosphate in a livestock via an antibody. The methods involve the development of an antibody against FGF-23 for the purpose of reducing phosphate...
US20170281737 UNIVERSAL PLATFORM FOR TARGETING THERAPIES TO TREAT NEUROLOGICAL DISEASES  
The present invention provides a universal delivery platform of functional, heterologous compounds to specific cells using toxins modified to include a heterologous compound. In one embodiment,...
US20170281643 COMPOUNDS AND METHODS FOR MODULATING FRATAXIN EXPRESSION  
The present technology relates to compositions and methods for modulating expression of genes, which include a target oligonucleotide sequence, such as repeats of a particular oligonucleotide...
9779785 Computer architecture using compute/storage tiles  
A computer architecture employs multiple intercommunicating tiles each holding an array of memory elements. Programmable decoding circuitry allows these memory elements to be used as local...
9777998 Device for camouflaging an object from infrared and low light cameras  
A device is provided for camouflaging an object from an infrared detection apparatus. The device includes a cloak positionable between the object and the infrared detection apparatus. The cloak...
9777331 Single nucleotide polymorphisms associated with bull fertility  
Single nucleotide polymorphic sites of the bovine MAP1B, PPP1R11, and DDX4 genes are associated with improved bull fertility as measured by e.g. sire conception rates. Nucleic acid molecules,...
9777185 Azlactone based thermally crosslinkable polymer coating for controlling cell behavior  
Random copolymers, crosslinked thin films of the random copolymers and cell culture substrates comprising the crosslinked thin films are provided. Also provided are methods of making and using the...
US20170279392 VARIABLE MAGNETIZATION MACHINE CONTROLLER  
A variable magnetization machine control system comprising a controller configured to generate a reversely rotating d-axis/q-axis current vector trajectory during a change in a magnetization state...
US20170279322 PERMANENT MAGNET SYNCHRONOUS MOTOR  
A permanent magnet synchronous motor includes a stator with a stator winding, a rotor with a rotor core rotatable relative to the stator, and a magnetic structure with at least one permanent...
US20170279148 Charge Transfer Mediator Based Systems for Electrocatalytic Oxygen Reduction  
Disclosed are systems for the electrocatalytic reduction of oxygen, having redox mediator/redox catalyst pairs and an electrolyte solution in contact with an electrode. The redox mediator is...
US20170275643 EXTENDING JUVENILITY IN GRASSES  
The present invention relates to compositions and methods for modulating the juvenile to adult developmental growth transition in plants, such as grasses (e.g. maize). In particular, the invention...
9771587 Compositions and methods to promote erythropoiesis  
Described herein are compositions and methods for enhancing erythropoiesis in an individual in need thereof. Specifically agents that decrease the expression of Exosc8, Exosc9, Dis3, Dis3L or...
9771561 Method of making primate cells expressing apelin receptor that have mesangioblast potential  
Methods for obtaining multipotent Apelin receptor-positive lateral plate mesoderm cells, mesenchymal stem cells, and mesangioblasts under serum-free conditions are disclosed.
9771556 Vitronectin-derived cell culture substrate for maintaining human pluripotent stem cells in a substantially undifferentiated state  
Vitronectin-derived cell culture substrates and methods of using the same for culturing pluripotent stem cells are presented. Also provided herein are defined culture systems for maintaining human...
9771412 Engineered intein for improved production of protein-intein fusions  
The invention discloses engineered non-self-cleaving inteins derived from Mxe GyrA inteins and methods of using such inteins to chemically modify proteins.
9770223 System and method for accelerated, time-resolved imaging  
A system and method for reconstructing a series of images of a subject includes acquiring medical image data from the subject with a medical imaging system and reconstructing a series of images of...
US20170270424 Method of Estimating Program Speed-Up in Highly Parallel Architectures Using Static Analysis  
The amount of speed-up that can be obtained by optimizing the program to run on a different architecture is determined by static measurements of the program. Multiple such static measurements are...
US20170269179 SYSTEM AND METHOD FOR CONTROLLING UNDESIRED MAGNETIC FIELD EFFECTS IN MAGNETIC RESONANCE IMAGING  
A system and method are provided for determining a spatial distribution of susceptibility in a subject using a magnetic resonance imaging (MRI) system. The method includes directing the MRI system...
US20170269089 Methods for Detection and Treatment of Colorectal Cancer  
This invention provides methods, reagents, and diagnostic and prognostic markers useful for minimally invasive identification, diagnosis, and therapeutic intervention in individuals with...
US20170266318 HYDROGEL MICROSPHERES CONTAINING PEPTIDE LIGANDS FOR GROWTH FACTOR REGULATION IN BLOOD PRODUCTS  
Vascular endothelial growth factor VEGF-sequestering hydrogel microspheres that have been prepared to selectively bind VEGF from blood products are disclosed herein. In one particular embodiment,...
9766166 Device and method incorporating a slideable lid for extracting a targeted fraction from a sample  
A device and a method for isolating a target from a biological sample are provided. The target is bound to solid phase substrate to form target bound solid phase substrate. The device includes a...
9765327 Induction of hemogenic endothelium from pluripotent stem cells  
Described herein are methods and related compositions for inducing differentiation of human pluripotent stem cells (hPSCs) into hemogenic endothelium with pan-myeloid potential or restricted...
9765299 Chemically defined albumin-free conditions for cardiomyocyte differentiation of human pluripotent stem cells  
Methods for generating high-yield, high-purity cardiomyocyte progenitors or cardiomyocytes from pluripotent cells are described. Wnt/β-catenin signaling is first activated in pluripotent cells,...
9763597 Local MRI breast coil and method of use  
A local breast coil is designed to be tightly coupled to the natural shape of the pendant breast to provide high SNR for diagnostic MR imaging applications, while still providing access for...
US20170260506 METHODS OF T CELL EXPANSION AND ACTIVATION  
The present disclosure relates to methods, cells, and compositions for preparing T cell populations and compositions for adoptive cell therapy. In particular, provided herein are methods for...
US20170258898 VERSIKINE FOR INDUCING AND POTENTIATING AN IMMUNE RESPONSE  
Disclosed are methods, kits, polypeptides, and pharmaceutical compositions for inducing an immune response in a subject, which may include a T-cell mediated immune response. The methods comprise...
US20170258888 INFLUENZA B VIRUS REPLICATION FOR VACCINE DEVELOPMENT  
The invention provides a composition useful to prepare high titer influenza B viruses, e.g., in the absence of helper virus, which includes internal genes from an influenza B virus vaccine strain...
US20170258805 INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE  
Compounds and salts thereof which are acyl-sulfonamides or certain carboxylic acids and which inhibit microbial growth or attenuate the virulence of pathogenic microorganisms and which inhibit...
9763216 Radiator localization  
A method of locating a radiator is provided. A channel measurement vector is defined that includes a signal value measured at each of a plurality of antennas in response to a signal transmitted...
9761669 Seed-mediated growth of patterned graphene nanoribbon arrays  
Graphene nanoribbon arrays, methods of growing graphene nanoribbon arrays, and electronic and photonic devices incorporating the graphene nanoribbon arrays are provided. The graphene nanoribbons...
9758569 Collagen mimics  
Novel collagen mimics are disclosed with a tripeptide unit having the formula (Xaa-Yaa-Gly)n, where one of the positions Xaa or Yaa is a bulky, non-electron withdrawing proline derivative. By...
9758472 Non-lactone carbocyclic and heterocyclic antagonists and agonists of bacterial quorum sensing  
Non-lactone carbocyclic and heterocyclic antagonists and agonists of bacterial quorum sensing. Pharmaceutical composition containing antagonists. Methods employing antagonists and agonists for...