Patents and Patent Applications from Virginia Commonwealth University


Matches 1 - 50 out of 190 1 2 3 4 >
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8172769 Method and apparatus for monitoring intra ocular and intra cranial pressure  
A method and apparatus for measuring acoustic energy applied to the head to detect increases in intracranial pressure. Acoustic eye patches are applied to a patient's eye or eyelid, and an...
US20120052517 METHODS FOR TESTING AN IMMUNE RESPONSE USING CULTURES OF T CELLS, B CELLS AND DENDRITIC CELLS  
The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic...
8114976 Cryptosporidium hominis genes and gene products for chemotherapeutic, immunoprophylactic and diagnostic applications  
Cryptosporidium hominis genes and gene products are provided. The genes and gene products are useful for chemotherapeutic, immunotherapeutic, immunoprophylactic and diagnostic applications.
8111860 Recreational bone conduction audio device, system  
A waterproof recreational audio device and method that transmits sound via transcutaneous bone conduction provides high fidelity musical signals to a user. The device can be worn on the head of a...
US20110313028 SUPPRESSOR OF AP-1  
Methods, compositions, and therapeutic products for use in the field of oncology and specifically, for the treatment of cancer and other diseases in which SARI is ameliorative or therapeutic and/or...
8071373 Co-culture lymphoid tissue equivalent (LTE) for an artificial immune system (AIS)  
The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic...
8067150 In-situ preservation (ISP) bridge method and solution for non-heart beating donors  
A method for rapid, in-situ flushing of organs of a non-heart beating donor, and solutions for carrying out the flushing, are provided. The method initiates organ preservation, and the solutions...
US20110280841 Electroprocessing in Drug Delivery and Cell Encapsulation  
The invention is directed to novel compositions comprising an electroprocessed material and a substance, their formation and use. The electroprocessed material can, for example, be one or more...
8042544 Prevention of ventilator associated pneumonia (VAP)  
Ventilator associated pneumonia (VAP) may be prevented in a patient, or its occurrence reduced in a population of patients, by disposing in a patient airway an anti-VAP device or an anti-VAP...
US20110183425 Protein Complexes and Screening Methods  
The application concerns an isolated protein complex comprising polypeptide components: (i) UTP20 HUMAN or a fragment, variant or homologue thereof; (ii) PWP2 HUMAN or a fragment, variant or...
7947262 Use of fullerenes for the treatment of mast cell and basophil-mediated disease  
Mast cell (MC) and peripheral blood basophil (PBB)-associated diseases are treated or prevented, or their symptoms are alleviated by the administration of water soluble fullerenes (buckeyballs) to...
7935298 Method of producing fibers by electrospinning at high pressures  
A process of making fibers by electrostatic spinning includes the use of a mixing vessel (10), a piston (15) for pressurizing the polymer, carbon dioxide sources (20) for lowering the viscosity of...
US20110093211 Method for Processing Protein Data  
A method of generating data indicating whether a set of proteins is a protein complex. The method comprises receiving as input experimental data indicating experimentally observed relationships,...
US20110060578 COMPREHENSIVE MODELING OF THE HIGHLY NETWORKED COAGULATION-FIBRINOLYSIS-INFLAMMATORY-IMMUNE SYSTEM  
An agent-based modeling system (ABMS) is employed to quantitatively analyze individual components of each system of the coagulation-immune/inflammatory-fibrinolysis system at every point of...
7888341 Combination of glivec (STI571) with a cyclin-dependent kinase inhibitor, especially flavopiridol, in the treatment of cancer  
The present invention pertains to a combination for simultaneous, separate or sequential use which comprises (a) a cyclin-dependent kinase inhibitor and (b)...
US20110009291 METHODS AND COMPOSITIONS FOR INCREASING MEMBRANE PERMEABILITY  
Methods and compositions for increasing membrane permeability are provided. One aspect provides protein resulting from a fusion between a membrane-active peptide and second peptide. Nucleic acids...
7847120 Compositions of allosteric hemoglobin modifiers and methods of making the same  
The present invention provides novel compositions of allosteric hemoglobin modifiers which are substantially free of impurities, specifically polymeric impurities. In one embodiment, the novel...
7842388 Functional polymers via surface modifying agents  
Polymers, and particularly conventional commodity bulk polymers, are modified to have a surface activity of interest using a surface modifying polymer that includes a moiety that favors migration...
US20100291058 Sealants for Skin and Other Tissues  
The present invention relates to sealants for skin and other tissues. The sealants include an electroprocessed material. The sealants may contain more than one electroprocessed materials and may...
7807366 Genetic markers for assessing risk of premature birth resulting from preterm premature rupture of membranes  
A method to identify women who are at risk for preterm delivery due to premature rupture of membranes (PPROM) is provided. The method entails detecting the presence of SERPINH1 gene variants that...
7794727 Polyvalent chimeric OspC vaccinogen and diagnostic antigen  
A chimeric polyvalent recombinant protein for use as a vaccine and diagnostic for Lyme disease is provided. The chimeric protein comprises epitopes of the loop 5 region and/or the alpha helix 5...
7781580 Stilbene derivatives as new cancer therapeutic agents  
Stilbene derivatives exhibit killing and suppression of growth activity against a variety of cancer cells, and are effective at suppressing tumor growth in vivo. The stilbene derivatives may be...
7771825 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Functional polymers via surface modifying agents
 
Polymers, and particularly conventional commodity bulk polymers, are modified to have a surface activity of interest using a surface modifying polymer that includes a moiety that favors migration...
7771793 Functional polymers via surface modifying agents, and methods for polymeric surface modification  
Polymers, and particularly conventional commodity bulk polymers, are modified to have a surface activity of interest using a surface modifying polymer that includes a moiety that favors migration...
7759082 Electroprocessed fibrin-based matrices and tissues  
The invention is directed to formation and use of electroprocessed fibrin as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can...
7727558 Polymeric delivery agents and delivery agent compounds  
Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are...
7709257 Models for vaccine assessment  
The present invention is directed to methods for constructing and using in vivo and in vitro models of aspects of human immunity and, in particular, construction of a human immune system model for...
7616771 Acoustic coupler for skin contact hearing enhancement devices  
There is provided hearing device improvements using modulation techniques adapted to the characteristics of auditory and vestibular hearing. One embodiment provides for extending hearing to the...
7615373 Electroprocessed collagen and tissue engineering  
The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered...
7610153 Multi-drug titration and evaluation  
Titration of a combination of drugs or treatment modalities within individual subjects is carried out using an evolutionary operation (EVOP) direct-search procedure such as the Nelder-Mead simplex....
7579373 Targeted bisplatinum polyamines as pro-drugs: selective release of platinum  
Pro-drug forms of linear polyamine-bridged platinum compounds and methods for their production and use are provided. The polyamine-bridge portion of the compounds is based on spermine or...
US20090155342 Mineral technologies (MT) for acute hemostasis and for the treatment of acute wounds and chronic ulcers  
Compositions comprising clay minerals and methods for their use in promoting hemostasis are provided. The compositions comprise clay minerals such as bentonite, and facilitate blood clotting when...
US20090149748 Portable Pulmonary Injury diagnostic Devices And Methods  
Lung injury such as pneumothorax now can be diagnosed reliably, portably and quickly. Vibro-acoustic waves are sent through the chest and the resulting wave is measured. By analyzing attenuation...
US20090104221 RAPID GENERATION OF T CELL-INDEPENDENT ANTIBODY RESPONSES TO T CELL-DEPENDENT ANTIGENS  
The present invention comprises the use of follicular dendritic cells (FDCs) or FDC-like cells to generate FDC-dependent, but T cell-independent, B cell responses to T cell-dependent antigens, with...
US20090069623 METHODS AND COMPOSITIONS FOR TREATMENT OR PREVENTION OF RADIATION-INDUCED FIBROSIS  
The present invention comprises methods and compositions for the treatment or prevention of radiation-induced fibrosis. Methods and compositions for the inhibition of CTGF are disclosed herein....
7468067 One hand tourniquet with locking mechanism  
Provided is a tourniquet having two opposing and pivotally movable plates. The plates comprise a clamp that pinches an elastomeric cord. The plates are pivotally biased together by a spring. The...
US20080280781 Methods and Compositions for Increasing Membrane Permeability  
Methods and compositions for increasing membrane permeability are provided. One aspect provides protein resulting from a fusion between a membrane-active peptide and second peptide. Nucleic acids,...
7442754 Molecular imprinting of small particles, and production of small particles from solid state reactants  
Small particles of polymeric material are produced by expansion of a mixture of monomers and a propellant. The size and shape of the particles can be precisely tailored by materials selection and...
7402594 Sulfated bis-cyclic agents  
Sulfated bis-cyclic compounds that are potent anticoagulants and methods for their manufacture are provided. The sulfated compounds are bis-cyclic moieties comprised of an isoquinoline ring joined...
7396590 Soft block with repeat units that favor migration to a surface and repeat units with an activity of interest, and polymeric articles or coatings using same  
Polymers, and particularly conventional commodity bulk polymers, are modified to have a surface activity of interest using a surface modifying polymer that includes a moiety that favors migration...
US20080159985 Electroprocessing in drug delivery and cell encapsulation  
The invention is directed to novel compositions comprising an electroprocessed material and a substance, their formation and use. The electroprocessed material can, for example, be one or more...
US20080139457 Therapeutic compositions comprising chorionic gonadotropins and HMG CoA reductase inhibitors  
The invention provides improved methods and compositions for the treatment of cancer in a subject comprising administering to said subject a therapeutically effective amount of a composition...
7374774 Electroprocessed material made by simultaneously electroprocessing a natural protein polymer and two synthetic polymers  
The invention is directed to novel compositions comprising an electroprocessed material and a substance, their formation and use. The electroprocessed material can, for example, be one or more...
US20080038352 Electroprocessed Collagen and Tissue Engineering  
The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered...
7310427 Recreational bone conduction audio device, system  
A waterproof recreational audio device and method that transmits sound via transcutaneous bone conduction provides high fidelity musical signals to a user. The device can be worn on the head of a...
7285687 Cannabinoids  
Compounds of the formula: wherein R, R1 and R4 are defined in the specification, and pharmaceutically acceptable salts, esters and tautomers thereof, having activity at peripheral cannabinoid...
7279555 Advanced antigen presentation platform  
The present invention provides particles for the presentation of haptens for the purpose of eliciting an immune response. The amino acid sequences of the monomers which make up the particles are...
7279500 Sulfonamide cannabinoid agonists and antagonists  
Cannabinoid agonists and antagonists are provided for use in the treatment of disorders such as acute and chronic pain, inflammation, loss of appetite, convulsions, multiple sclerosis, nausea and...
7262030 Multiple sequencible and ligatible structures for genomic analysis  
High throughput methods and kits for single nucleotide polymorphism (SNP) genotyping are provided. The methods involve utilizing nested PCR amplification reactions which produce sequencible and...
US20070141022 POLYMERIC DELIVERY AGENTS AND DELIVERY AGENT COMPOUNDS  
Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are...
Matches 1 - 50 out of 190 1 2 3 4 >