Patents and Patent Applications from University of Washington


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9840539 High affinity digoxigenin binding proteins  
Isolated polypeptides with steroid binding activity and methods for their use as therapeutics and detection agents are disclosed herein.
US20170347951 SYSTEMS AND METHODS OF IDENTIFYING MOTION OF A SUBJECT  
Systems and methods of identifying medical disorders in one or more subjects are disclosed herein. In one embodiment, sound is transmitted toward a subject and at least a portion of the sound...
9834823 Primers, assays and methods for detecting an E. coli subtype  
Disclosed are primers, probes, and single nucleotide polymorphisms (SNP) specific to a distinct subclones of the E. coli sequence type 131 (ST131). Also disclosed are methods and assay kits useful...
9833148 Methods and systems for integrated imaging using optical coherence tomography and photoacoustic imaging  
Systems and methods for photoacoustic imaging are provided. Photoacoustic signals are excited from a body and the excited photoacoustic signals are detected with a low coherence interferometer...
US20170342316 NANOPARTICLES FOR PHOTOVOLTAIC AND LED DEVICES AND METHODS OF MAKING THE SAME  
The present disclosure relates to a composition that includes a particle and a surface species, where the particle has a characteristic length between greater than zero nm and 100 nm inclusively,...
US20170342126 HLA-DR BINDING PEPTIDES AND THEIR USES  
The present invention provides HLA-DR (MHC class II) binding peptides derived from the ovarian/breast cancer associated antigens, Human Epidermal Growth Factor Receptor 2 (HER-2/neu),...
US20170340390 Computer-Assisted Osteocutaneous Free Flap Reconstruction  
Example methods and systems to facilitate osteocutaneous free flap reconstructions are provided. One example method involves causing a surgical navigation system to display a representation of a...
9827573 Electrostatic precipitator  
An electrostatic precipitator may have different collecting and repelling electrodes surfaces. For example, a collecting electrode may have an internal conductive portion. A non-conductive or less...
9824596 Unmanned vehicle searches  
A method of planning a flight path for a search can include receiving, by a control system, an indication of a search area boundary; receiving, by the control system, an indication of a selected...
US20170331509 AMBIENT BACKSCATTER TRANCEIVERS, APPARATUSES, SYSTEMS, AND METHODS FOR COMMUNICATING USING BACKSCATTER OF AMBIENT RF SIGNALS  
Apparatuses, systems, ambient backscatter transceivers, and methods for modulating a backscatter of an ambient RF signal are described. An example system may include an ambient backscatter...
US20170328834 Systems, Devices, and Methods for Separating, Concentrating, and/or Differentiating Between Cells From a Cell Sample  
Embodiments are generally related to differentiating and/or separating portions of a sample that are of interest from the remainder of the sample. Embodiments may be directed towards separating...
US20170327813 3D Printable Hydrogel Materials  
Hydrogel compositions including a polymer uniformly embedded with a loading agent are provided. Also provided are methods for extrusion printing hydrogel compositions to provide extruded hydrogel...
US20170326790 Additive Manufacturing Using Stimuli-Responsive High-Performance Polymers  
The present invention provides high performance polymer (HPP) compositions, methods, processes, and systems for the manufacture of three-dimensional articles made of polymers using molding or 3D...
9816246 Pile with sound abatement for vibratory installations  
A noise-attenuating pile comprising a pile driving shoe, an outer tube that engages the pile driving shoe, and an inner member that extends through the outer tube and engages the pile driving...
9815885 Inducible mutagenesis of target genes  
The present invention relates generally to mutagenesis of target genes that takes advantage of the natural mutagenic capabilities of B cells, and enhances those capabilities by bringing the...
US20170323441 FILTER-FREE DEVICES AND SYSTEMS FOR MEASURING FLUORESCENCE OF A MICROFLUIDIC ASSAY AND ASSOCIATED METHODS OF USE  
The present technology relates generally to devices, systems, and methods for detecting an analyte from a microfluidic assay. In some embodiments, a method for detecting the analyte includes...
US20170322229 HIGH AFFINITY VITAMIN D3 BINDING PROTEINS  
The present disclosure provides isolated polypeptides with vitamin D3 binding activity and methods for their use as detection agents. In another aspect, the invention provides recombinant...
9811613 Fenestration template for endovascular repair of aortic aneurysms  
To provide simple yet accurate stent graft fenestration, a patient-specific fenestration template is used as a guide for graft fenestration. To generate the fenestration template, a patient's...
9811583 Systems and methods for selection-based contextual help retrieval  
Described herein are systems and methods for selection-based contextual help retrieval. One example method involves (a) receiving first-query data including contextual data, the contextual data...
9810758 Method and system for concentrating magnetization of nuclear spins  
Apparatuses and methods are provided for concentrating the magnetization of nuclear spins within a body, in one apparatus, a body having an electron spin moments and nuclear spin moments may...
9810693 Chromophoric polymer dots  
The present invention provides, among other aspects, stabilized chromophoric nanoparticles. In certain embodiments, the chromophoric nanoparticles provided herein are rationally functionalized...
9809904 Methods for retrieval of sequence-verified DNA constructs  
In some embodiments, methods of recovering a sequence-verified target nucleic acid are provided. In some embodiments, such methods may include tagging each member of a nucleic acid library with a...
9809633 Reagents and methods for treating dental disease  
Peptide-based reagents, compositions and oral care products containing the peptide-based reagents, and methods for using the peptide-based reagents, compositions, or oral care products to treat...
9809632 Universal protein tag for double stranded nucleic acid delivery  
Disclosed herein are chimeric proteins that include one or more double stranded nucleic acid binding domains (dsNABD) and one or more polyHis domains, and compositions that further include a...
9809594 Non-fullerene electron acceptors for organic photovoltaic devices  
Non-fullerene electron acceptors for highly efficient organic photovoltaic devices are described. The non-fullerene electron acceptors have an extended, rigid, π-conjugated electron-deficient...
9808993 Method for solid freeform fabrication  
The present invention provides methods, processes, and systems for the manufacture of three-dimensional articles made of polymers using 3D printing. A layer of prepolymer is deposited on a build...
9808808 Electrostatic precipitator  
An electrostatic precipitator is constructed with collecting and repelling electrodes. The collecting electrode is partially shielded from gas shear forces by a shielding structure. The shielding...
9808472 Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies  
Described herein are methods and compositions for the treatment of prostate cancer in a subject in need thereof. The prostate cancer may be a castration resistant and an androgen receptor...
US20170317529 DISTRIBUTED CONTROL ADAPTIVE WIRELESS POWER TRANSFER SYSTEM  
A wireless power transfer system (100) includes a transmitter (110) configured to transmit power to a receiver (120), for example, through coupled resonators (111,121). The transmitter receives...
US20170315148 SCANNING THERMO-IONIC MICROSCOPY  
A method of scanning probe microscopy includes supplying heat to a scanning probe. The method also includes receiving a scanning probe deflection signal, where the scanning probe deflection signal...
US20170313656 Branched Discrete PEG Constructs  
Disclosed are general and “substantially pure” branched discrete polyethylene glycol constructs useful in attaching to a variety of biologically active groups, for example, preferential locators,...
US20170312171 METHODS AND DEFIBRILLATORS UTILIZING HIDDEN MARKOV MODELS TO ANALYZE ECG AND/OR IMPEDANCE SIGNALS  
Examples described herein include defibrillators or other medical equipment that may employ hidden Markov models to classify cardiac rhythms in ECG signals. Hidden Markov models may additionally...
9803017 Soluble MIC neutralizing monoclonal antibody for treating cancer  
Disclosed are compositions and methods relating to antibodies that bind soluble Major Histocompatibility Complex class I chain-related (sMIC). Specifically, disclosed are antibodies designed or...
US20170310889 EXTENDED DEPTH OF FOCUS FOR HIGH-RESOLUTION OPTICAL IMAGE SCANNING  
Methods and systems for acquiring and/or projecting images from and/or to a target area are provided. Such a method or system can includes an optical fiber assembly which may be driven to scan the...
US20170307313 BAFFLED-TUBE RAM ACCELERATOR  
A baffled ram accelerator system includes a ram accelerator tube with an inner surface and an outer surface and a plurality of baffles disposed on the inner surface. The plurality of baffles forms...
US20170306029 WNT SIGNALING AGONIST MOLECULES  
Wnt signaling agonist compositions and methods for their use are provided. Wnt signaling agonists of the invention comprise a frizzled binding moiety, which is fused or conjugated to an LRP5 or...
9800808 Remapping methods to reduce distortions in images  
The present invention provides software, methods, and systems for characterizing an actual scan pattern of a scanning beam device. The characterization of the actual scan pattern may be used in an...
9797840 Highly fluorescent polymer nanoparticle  
Fluorescent nanoparticles are provided. The nanoparticles are formed from poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-(1-cyanovinylene-1,4- phenylene)]. Also provided are methods for imaging a target...
US20170299494 PARTICLE POSITIONING DEVICE WITH PERIODIC DIELECTRIC STRUCTURE  
Devices and techniques for a particle positioning device are generally described. In some examples, a fluid may be introduced to a channel formed on a first surface of a substrate. In various...
US20170296633 Compositions and Methods for Treating Celiac Sprue Disease  
The invention provides compositions and methods for treating celiac sprue.
9790536 Methods for assaying alpha-L-iduronidase enzymatic activity  
Methods for assaying α-L-iduronidase enzymatic activity and methods for screening newborns for Mucopolysaccharidosis Type-I.
9790479 Therapeutic nuclease compositions and methods  
Hybrid nuclease molecules and methods for treating an immune-related disease or disorder in a mammal, and a pharmaceutical composition for treating an immune-related disease in a mammal.
US20170294015 SYSTEMS AND METHODS FOR QUANTITATIVE ASSESSMENT OF MICROVASCULATURE USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY  
A five-index quantitative analysis of OCT angiograms is disclosed. One method of analyzing an anatomical region of interest of a subject includes acquiring vascular image data from the region of...
US20170292160 Methods for Diagnosing and Treating Eye-Length Related Disorders  
The invention provides to methods for diagnosing eye-length related disorders, including myopia. The invention also provides methods for treating and limiting eye-length related disorders,...
US20170290992 Systems and Methods for Inhibiting Heterotopic Ossification  
Systems and methods for mitigating the formation of heterotopic ossification lesions by delivering a neuromuscular inhibitor employ a delivery device to distribute injection of the neuromuscular...
US20170290986 Ampule Autoinjector Systems And Methods  
An autoinjector is described that includes an outer body, a first trigger, an output needle, and a first compartment. The first compartment is positioned within the outer body and includes (i) a...
US20170290644 Medical Implant With Discontinuous Osseointigrative Surface  
A medical implant includes a base portion configured for implantation into a bone of a patient. The base portion is formed from an electrically insulating and biocompatible base material with...
9786469 Thin-ice grid assembly for cryo-electron microscopy  
A grid assembly for cryo-electron microscopy may be fabricated using standard nanofabrication processes. The grid assembly may comprise two support members, each support member comprising a...
9784730 Nanoparticle for targeting brain tumors and delivery of O6-benzylguanine  
Nanoparticle having a crosslinked chitosan-polyethylene oxide oligomer copolymer coating to which O6-benzylguanine is covalently coupled, compositions that include the nanoparticle, and methods...
US20170283475 CANCER VACCINE COMPOSITIONS AND METHODS OF USE THEREOF  
The present application describes compositions that include an epitope of a peptide that elicits an immune response in a subject following administration. The compositions described herein include...