Patents and Patent Applications from University of Washington


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US20180046704 Systems and Methods for Selection-Based Contextual Help Retrieval  
Described herein are systems and methods for selection-based contextual help retrieval. One example method involves (a) receiving first-query data including contextual data, the contextual data...
US20180043778 ELECTROCHEMICAL CELL DIAGNOSTIC SYSTEMS AND METHODS USING SECOND ORDER AND HIGHER HARMONIC COMPONENTS  
Electrochemical cell diagnostic systems and methods are described. Examples include systems having a signal generator configured to apply a stimulus having a stimulus frequency to at least one...
US20180043029 STABILIZED POLYMERIC CARRIERS FOR THERAPEUTIC AGENT DELIVERY  
Polymeric carriers for the delivery of therapeutic agents and methods for making and using the same. The polymeric carriers include copolymers, diblock copolymers, polymeric architectures that...
US20180042473 METHODS AND SYSTEMS FOR ENHANCING MICROANGIOGRAPHY IMAGE QUALITY  
Systems and methods for enhancing quality of a flow image of a sample of a subject are provided. The method comprises acquiring a first flow image from a plurality of first OMAG scans of the...
9894329 Scanning laser projection display for small handheld devices  
Image projection devices, high-speed fiber scanned displays and related methods for projecting an image onto a surface and interfacing with the projected image are provided. A method for...
US20180038792 REMOVABLE CHROMATIC WITNESS ASSEMBLY, SYSTEM, AND METHOD TO MONITOR THERMAL EVENTS AND IMPACT EVENTS ON A COMPOSITE STRUCTURE  
There is provided a removable chromatic witness assembly, system, and method to monitor thermal events and impact events on a surface of a composite structure. The removable chromatic witness...
US20180037961 PRIMERS, PROBES AND METHODS FOR SENSITIVE, SPECIFIC DETECTION AND MONITORING OF HIV-1 AND HCV  
Primers and probes for detecting an RNA virus, including HIV, HIV-1 subtypes of the M and O groups, and HCV, in a sample. The primers and probes can be used for monitoring the efficacy of...
9888215 Indoor scene capture system  
An indoor scene capture system is provided that, with a handheld device with a camera, collects videos of rooms, spatially indexes the frames of the videos, marks doorways between rooms, and...
US20180030429 Polypeptide Assemblies and Methods for the Production Thereof  
The application discloses multimeric assemblies including multiple oligomeric substructures, where each oligomeric substructure includes multiple proteins that self-interact around at least one...
US20180028794 DRAINAGE SYSTEMS FOR EXCESS BODY FLUIDS AND ASSOCIATED METHODS  
Drainage systems for excess body fluids and associated methods are disclosed herein. A body fluid drainage system in accordance with an embodiment of the present technology, for example, can...
9882428 Energy harvesting and control for sensor node  
An integrated circuit, such as included as a portion of a sensor node, can include a regulator circuit having an input coupleable to an energy harvesting transducer. The integrated circuit can...
US20180025791 Plasma Confinement System and Methods for Use  
A plasma confinement system is provided that includes a confinement chamber that includes one or more enclosures of respective helicity injectors. The one or more enclosures are coupled to ports...
US20180022756 COMPOUNDS AND METHODS FOR PREVENTING OR TREATING SENSORY HAIR CELL DEATH  
Disclosed herein are compounds, and pharmaceutical compositions that include such compounds, for preventing or treating hearing loss. The compounds and pharmaceutical compositions described herein...
US20180022709 Compositions and Methods for Treating Toxoplasmosis, Cryptosporidiosis, and Other Apicomplexan Protozoan Related Diseases  
Compositions and methods for the treatment of toxoplasmosis, caused by the infectious eukaryotic parasite Toxoplasma gondii (T. gondii) and for the treatment of cryptosporidiosis, caused by the...
9872613 Monitoring disposition of tethered capsule endoscope in esophagus  
A system for imaging a body lumen includes a scanning capsule with a scanning device, a flexible tether coupled to the scanning capsule, a reel coupled to the flexible tether, and one or more...
9872606 Adaptive control of a fiber scanner with piezoelectric sensing  
Improved systems, methods, and devices relating to optical fiber scanners are provided. In one aspect, a scanning apparatus includes an optical fiber and a piezoelectric actuator coupled to the...
US20180016339 SOLUBLE MIC NEUTRALIZING MONOCLONAL ANTIBODY FOR TREATING CANCER  
Described herein are compositions and methods relating to antibodies that bind soluble MIC (sMIC), e.g. for the treatment of MIC-positive cancers.
US20180014971 THERMALLY CONDUCTIVE GRAFT  
The present disclosure provides thermally conductive grafts and methods of passively cooling a hyperthermic region and preventing epilepsy, neural inflammation, and other neurological...
9868937 Cell and gene based methods to improve cardiac function  
Compositions and methods for improving cardiac function, myocardial contractility and relaxation in a mammal are provided. Cardiomyocytes transfected with one or more expression vectors comprising...
9867999 Pulse amplifier for driving ultrasound transducers  
Embodiments of the invention include improved radiofrequency (RF) pulse amplifier systems that incorporate an energy array comprising multiple capacitors connected in parallel. The energy array...
US20180011101 MATERIALS AND METHODS FOR DETECTING ANDROGEN RECEPTOR SPLICE VARIANTS AND USES THEREOF  
The present disclosure relates to materials and methods for evaluating prostate cancer using binding entities (such as antibodies) that bind to the N-terminus and the C-Terminus of androgen...
US20180011016 SYSTEM AND METHOD FOR IMMERSION FLOW CYTOMETRY  
An immersion cytometry system (200, 250) having a primary focusing optic immersed in a fluid stream (209) containing suspended particles (212). The system includes a light source (202) configured...
US20180008671 PROLONGED ANTI-DIABETIC EFFECT OF FIBROBLAST GROWTH FACTOR 1 (FGF1)  
Disclosed are compositions and methods for inducing sustained diabetes remission by single administration of FGF1 to the brain. The composition and methods described herein result in basal glucose...
9862792 Diblock copolymers and polynucleotide complexes thereof for delivery into cells  
Described herein are copolymers, and methods of making and utilizing such copolymers. Such copolymers have at least two blocks: a first block that has at least one unit that is hydrophilic at...
US20180001544 Method for Solid Freeform Fabrication  
The present invention provides methods, processes, and systems for the manufacture of three-dimensional articles made of polymers using 3D printing. A layer of prepolymer is deposited on a build...
9855239 Methods for the treatment and prevention of age-related retinal dysfunction  
A method of treating or preventing age-related retinal dysfunction involves administering to a patient a pharmaceutically effective amount of a synthetic retinal derivative repeatedly over a...
US20170370387 ACTIVE CONTROL OF VORTICES FOR SKIN FRICTION REDUCTION  
Systems and method for active control of stationary vortices for aerodynamic structures are disclosed herein. In one embodiment, a method for active control of vortices over a solid surface...
US20170369892 HORMONE DEGRADABLE CRISPR-BASED TRANSCRIPTION FACTORS  
Synthetic signal transduction systems are provided. The synthetic signal transduction system may be a hormone degradable CRISPR-based transcription factor including a nuclease null Cas9 protein, a...
US20170369558 NEUTRALIZING ANTIBODIES TO HIV-1 AND THEIR USE  
Monoclonal neutralizing antibodies are disclosed that specifically bind to the CD4 binding site of HIV-1 gp120. Monoclonal neutralizing antibodies also are disclosed that specifically bind to...
US20170367838 DEVICES AND METHODS FOR METATARSOPHALANGEAL ARTHROPLASTY PROCEDURES  
The present technology relates generally to devices and methods for arthroplasty procedures. In some embodiments, for example, a device is disclosed for use during an arthroplasty procedure of a...
US20170363648 Biosensors Engineered from Conditionally Stable Ligand-Binding Domains  
Disclosed is a biosensor engineered to conditionally respond to the presence of specific small molecules, the biosensors including conditionally stable ligand-binding domains (LBDs) which respond...
US20170362635 MUSCLE-SPECIFIC CRISPR/CAS9 EDITING OF GENES  
Pharmaceutical compositions including a muscle-specific nuclease cassette, one or more guide RNA cassettes, and a delivery system for delivery of the muscle-specific nuclease cassette and the one...
US20170360886 METHODS FOR TREATING AND PREVENTING CARDIOMYOPATHY  
Methods for treating patients having a cardiomyopathy are provided. Additionally, methods for prophylactically treating patients at risk of developing a cardiomyopathy are provided. Methods for...
9840539 High affinity digoxigenin binding proteins  
Isolated polypeptides with steroid binding activity and methods for their use as therapeutics and detection agents are disclosed herein.
US20170347951 SYSTEMS AND METHODS OF IDENTIFYING MOTION OF A SUBJECT  
Systems and methods of identifying medical disorders in one or more subjects are disclosed herein. In one embodiment, sound is transmitted toward a subject and at least a portion of the sound...
9834823 Primers, assays and methods for detecting an E. coli subtype  
Disclosed are primers, probes, and single nucleotide polymorphisms (SNP) specific to a distinct subclones of the E. coli sequence type 131 (ST131). Also disclosed are methods and assay kits useful...
9833148 Methods and systems for integrated imaging using optical coherence tomography and photoacoustic imaging  
Systems and methods for photoacoustic imaging are provided. Photoacoustic signals are excited from a body and the excited photoacoustic signals are detected with a low coherence interferometer...
US20170342316 NANOPARTICLES FOR PHOTOVOLTAIC AND LED DEVICES AND METHODS OF MAKING THE SAME  
The present disclosure relates to a composition that includes a particle and a surface species, where the particle has a characteristic length between greater than zero nm and 100 nm inclusively,...
US20170342126 HLA-DR BINDING PEPTIDES AND THEIR USES  
The present invention provides HLA-DR (MHC class II) binding peptides derived from the ovarian/breast cancer associated antigens, Human Epidermal Growth Factor Receptor 2 (HER-2/neu),...
US20170340390 Computer-Assisted Osteocutaneous Free Flap Reconstruction  
Example methods and systems to facilitate osteocutaneous free flap reconstructions are provided. One example method involves causing a surgical navigation system to display a representation of a...
9827573 Electrostatic precipitator  
An electrostatic precipitator may have different collecting and repelling electrodes surfaces. For example, a collecting electrode may have an internal conductive portion. A non-conductive or less...
9824596 Unmanned vehicle searches  
A method of planning a flight path for a search can include receiving, by a control system, an indication of a search area boundary; receiving, by the control system, an indication of a selected...
US20170331509 AMBIENT BACKSCATTER TRANCEIVERS, APPARATUSES, SYSTEMS, AND METHODS FOR COMMUNICATING USING BACKSCATTER OF AMBIENT RF SIGNALS  
Apparatuses, systems, ambient backscatter transceivers, and methods for modulating a backscatter of an ambient RF signal are described. An example system may include an ambient backscatter...
US20170328834 Systems, Devices, and Methods for Separating, Concentrating, and/or Differentiating Between Cells From a Cell Sample  
Embodiments are generally related to differentiating and/or separating portions of a sample that are of interest from the remainder of the sample. Embodiments may be directed towards separating...
US20170327813 3D Printable Hydrogel Materials  
Hydrogel compositions including a polymer uniformly embedded with a loading agent are provided. Also provided are methods for extrusion printing hydrogel compositions to provide extruded hydrogel...
US20170326790 Additive Manufacturing Using Stimuli-Responsive High-Performance Polymers  
The present invention provides high performance polymer (HPP) compositions, methods, processes, and systems for the manufacture of three-dimensional articles made of polymers using molding or 3D...
9816246 Pile with sound abatement for vibratory installations  
A noise-attenuating pile comprising a pile driving shoe, an outer tube that engages the pile driving shoe, and an inner member that extends through the outer tube and engages the pile driving...
9815885 Inducible mutagenesis of target genes  
The present invention relates generally to mutagenesis of target genes that takes advantage of the natural mutagenic capabilities of B cells, and enhances those capabilities by bringing the...
US20170323441 FILTER-FREE DEVICES AND SYSTEMS FOR MEASURING FLUORESCENCE OF A MICROFLUIDIC ASSAY AND ASSOCIATED METHODS OF USE  
The present technology relates generally to devices, systems, and methods for detecting an analyte from a microfluidic assay. In some embodiments, a method for detecting the analyte includes...
US20170322229 HIGH AFFINITY VITAMIN D3 BINDING PROTEINS  
The present disclosure provides isolated polypeptides with vitamin D3 binding activity and methods for their use as detection agents. In another aspect, the invention provides recombinant...