Patents and Patent Applications from University of Virginia


Match Document Document Title
US20180205306 CRITICAL-MODE-BASED SOFT-SWITCHING TECHNIQUES FOR THREE-PHASE BI-DIRECTIONAL AC/DC CONVERTERS  
Critical-mode soft-switching techniques for a power converter are described. In one example, a power converter includes a converter electrically coupled between an alternating current (AC) power...
US20180200510 NANOSECOND PULSED ELECTRIC FIELDS CAUSE MELANOMAS TO SELF-DESTRUCT  
Methods for a new, drug-free therapy for treating solid skin tumors through the application of nanosecond pulsed electric fields (“nsPEFs”) are provided. In one embodiment of the invention, the...
10024073 Pool cleaner with laser range finder system and method  
A swimming pool cleaner includes a chassis that supports a motor and a camera that is associated with the chassis and configured to identify at least one object. A controller is in communication...
US20180195181 METHODS AND APPARATUSES FOR PRODUCTION OF CARBON, CARBIDE ELECTRODES, AND CARBON COMPOSITIONS  
Method comprising providing at least one solid carbide chemical compound and reducing a metal cation with use of the solid carbide chemical compound. A method comprising producing elemental carbon...
US20180194954 POROUS THERMALLY INSULATING COMPOSITIONS CONTAINING HOLLOW SPHERICAL NANOPARTICLES  
A method of thermally insulating a surface, the method comprising applying a coating of a thermally insulating composition onto said surface, wherein said thermally insulating composition...
10013007 Hybrid interleaving structure with adaptive phase locked loop for variable frequency controlled switching converter  
In a multi-phase power converter using a phase-locked loop (PLL) arrangement for interleaving of pulse frequency modulated (PFM) pulses of the respective phases, improved transient response,...
10011686 Viscoelastic silicone rubber compositions  
The invention provides for new viscoelastic silicone rubbers and compositions and methods for making and using them. The invention provides for viscoelastic silicone rubbers that are stiffer on...
10010692 Systems, devices, and methods for changing therapeutic aerosol size and improving efficiency of ventilation and aerosol drug delivery  
A mixer-heater device provides controllable reduction in aerosol droplet size. Additionally, an intermittent delivery mode for administering an aerosol to a patient may take into account patient...
10010584 Treatment of depressive disorders  
The invention provides for the use of carbonic anhydrase activators; protein kinase C activators and FGF-18 to treat depressive disorders. The invention also relates to improved animal models and...
US20180183269 ENERGY HARVESTING AND CONTROL FOR SENSOR NODE  
An integrated circuit, such as included as a portion of a sensor node, can include a regulator circuit having an input coupleable to an energy harvesting transducer. The integrated circuit can...
US20180171970 WIND TURBINE HAVING RELEASABLE VANES  
A wind turbine is disclosed. The wind turbine includes a shaft rotatable about an axis, a plurality of hubs fixedly attached to the shaft, and a plurality of vanes. The vanes are releasably...
US20180168665 ADJUSTABLE DEVICE FOR IDENTIFYING A TARGET LOCATION FOR A TIBIAL TUNNEL AND RELATED METHOD THEREOF  
An adjustable device for identifying the target location for, and placement of, a bone tunnel wherein the device is capable of measuring a total distance across a region of an anatomic structure....
US20180168131 Walkway Device and Method for Quantitative Analysis of Gait and its Modification in Rodents  
A system and method for quantitatively assessing the changes in control of asymmetric locomotor behavior of an animal comprising analyzing the phase modulation in response to imposed asymmetric...
10001105 Compact electromagnetic plasma ignition device  
A quarter wave coaxial cavity resonator for producing corona discharge plasma from is presented. The quarter wave coaxial cavity resonator has a folded cavity made of opposing concentric cavity...
10000453 Chelation directed C—H activation reactions catalyzed by solid-supported palladium(II) catalysts  
Chelation directed C—H activation reactions that are catalyzed by Pd(11) on Multi-Walled Carbon Nanotubes (MWCNT), Single-Walled Carbon Nanotubes (SWCNT), or graphene are provided. The reactions...
US20180167140 POSITION LOCALIZATION USING VISIBLE LIGHT COMMUNICATION  
Visible-light communication (VLC) is an optical wireless communication technique that uses light emitting diodes (LEDs) or other optical sources to transmit information to a user equipment (UE)...
US20180161086 IMMUNOTHERAPEUTIC METHODS USING IRREVERSIBLE ELECTROPORATION  
Methods for treating tissue with irreversible electroporation and immunotherapy are described. The methods include placing a probe in tissue within a human body, wherein the probe has at least a...
9998124 Low power clock source  
An ultra-low power clock source includes a compensated oscillator and an uncompensated oscillator coupled by a comparator circuit. In an example, the compensated oscillator is more stable than the...
9998111 Power switch drivers with equalizers for paralleled switches  
Capacitors connected between gate terminals of a plurality of parallel-connected power transistors are charged and discharged in each switching cycle to provide a plurality of power transistor...
9997342 Method and device for mass spectrometric analysis of biomolecules using charge transfer dissociation (CTD)  
Provided herein are devices, systems, and methods of CTD mass spectrometry analysis of biomolecules.
9994865 PEG-Prom mediated surface expression of avidin/streptavidin  
The presently disclosed subject matter relates to compositions and methods directed to cancer theranostic nucleic acid constructs that permit simultaneous cancer-specific viral replication,...
9993585 Method suction device and related method thereof  
A system or device for providing medical suction, particularly for intubating patients, wherein the system or device helps prevent clogging from solids dispersed in the liquid to be suctioned....
US20180154377 SYSTEM CONTROL BASED ON ACOUSTIC SIGNALS  
An example system includes at least one acoustic sensor configured to generate at least one time-dependent acoustic data signal indicative of an acoustic signal generated by a thermal spray system...
9989620 Estimating the location of a wireless terminal based on radio-frequency pattern matching and cooperative measurements  
A method for estimating the location of a wireless terminal is disclosed that is based on using: the known location of one or more devices, empirical data that indicates the relative position of...
9989611 Systems and methods for image reconstruction using variable-density spiral trajectory  
In image reconstruction using a variable-density spiral trajectory, a method includes acquiring magnetic resonance (MR) data, which includes determining a multi-level undersampling pattern based...
9989497 Front end circuitry with analog sampling and decoding for ultrasound imaging systems and methods of use  
Pulse-echo imaging systems and methods are provided, including a transmit code sequencer and a pulse generation circuit, The transmit code sequencer is configured to input a transmit code sequence...
9987576 Frequency-based filtering of mechanical actuation using fluidic device  
A mechanical input to a fluidic filter network can be actuated. The fluidic filter network can include respective branches fluidically coupling the mechanical input to respective deformable...
9986910 Intuitive techniques and apparatus for ophthalmic imaging  
Apparatus and techniques can include using one or more of a portable or fixed optical system to obtain images of a desired anatomical target, such as the fundus region of a human eye. The optical...
US20180147275 CHIMERIC INFECTIOUS DNA CLONES, CHIMERIC PORCINE CIRCOVIRUSES AND USES THEREOF  
The present invention relates to infectious DNA clones, infectious chimeric DNA clones of porcine circovirus (PCV), vaccines and means of protecting pigs against viral infection or postweaning...
9981012 Compositions and methods for protecting the kidney from ischemia reperfusion injury  
The effects of hepcidin treatment on mitigating renal ischemiareperfusion injury (IRI) and acute kidney injury (AKI) by decreasing iron availability and ROS-mediated cell death were tested....
9979348 Low voltage crystal oscillator (XTAL) driver with feedback controlled duty cycling for ultra low power  
A low voltage crystal oscillator (XTAL) driver with feedback controlled duty cycling for ultra low power biases an amplifier for an XTAL in the sub-threshold operating regime. A feedback control...
9977652 System, method, and computer-readable medium for high throughput pseudo-random number generation  
Disclosed embodiments include systems, methods, and computer-readable media for generating pseudo-random numbers. Disclosed embodiments may receive, by the at least one processor, range data...
9977489 Compressed sampling and memory  
Aspects of a low power memory buffer are described. In one embodiment, a sampling rate of a signal is adjusted to identify extrema of a signal. An extrema pulse is generated and, in response to...
9977112 Object localization with RFID infrastructure  
Object localization with an radio-frequency identification (RFID) infrastructure is described. A plurality of transmission power levels established by an RFID reader can be searched to determine a...
9974758 Sphingosine kinase type 1 inhibitors and uses thereof  
Provided are inhibitors of sphingosine kinase Type I that are useful in a number of applications, indications and diseases, as well as for monitoring pharmacokinetics and patient management. These...
US20180135130 NOVEL METHYLATION SITE REGULATING EXPRESSION OF MDA-9/SYNTENIN  
Methods of prognosing the outcome of cancer and/or cancer treatment are provided. The methods involve quantitating the level of methylation at a site that regulates expression of the...
US20180132711 Self-Illuminated Handheld Lens for Retinal Examination and Photography and Related Method thereof  
System and method directed towards providing full and even illumination of a patient's retina through lighting integrated into a handheld fundus lens. By integrating the lighting, the method and...
9973086 Low input voltage boost converter with peak inductor current control and offset compensated zero detection  
The low input voltage boost converter with peak inductor current control and offset compensated zero detection provide a boost converter scheme to harvest energy from sources with small output...
9970781 Apparatus for three-axis IMU calibration with a single-axis rate table  
Various methods and apparatuses are provided for calibrating a three-axis IMU sensor package using a single-axis rate table. In one embodiment, a method includes adjusting an x-axis position of a...
9968283 System and method for the inference of activities of daily living and instrumental activities of daily living automatically  
A method and related system to, among other things, automatically infer answers to all of the ADL questions and the first four questions of the IADL in the home. The inference methods detect the...
US20180127457 NOVEL CHOLESTEROL METABOLITE, 5-CHOLESTEN, 3BETA-25-DIOL, DISULFATE (25HCDS) FOR THERAPY OF METABOLIC DISORDERS, HYPERLIPIDEMIA, DIABETES, FATTY LIVERS DISEASES AND ATHEROSCLEROSIS  
5-cholesten, 3β,25-diol, disulfate (25HCDS) has been found to be an authentic PPARγ agonist and LXR antagonist, and is used for the therapy of lipid disorders and inflammatory diseases, including...
US20180125565 IRREVERSIBLE ELECTROPORATION USING TISSUE VASCULATURE TO TREAT ABERRANT CELL MASSES OR CREATE TISSUE SCAFFOLDS  
The present invention relates to the field of medical treatment of diseases and disorders, as well as the field of biomedical engineering. Embodiments of the invention relate to the delivery of...
9966874 Power-cell switching-cycle capacitor voltage control for modular multi-level converters  
In a modular multi-level power converter, additional switching states are interleaved between main switching states that control output voltage or waveform. The additional switching states provide...
9962101 Analysis of cardiac rhythm using RR interval characterization  
A method for analysis of cardiac rhythms, based on calculations of entropy and moments of interbeat intervals. An optimal determination of segments of data is provided that demonstrate statistical...
9962071 Self-illuminated handheld lens for retinal examination and photography and related method thereof  
System and method directed towards providing full and even illumination of a patient's retina through lighting integrated into a handheld fundus lens. By integrating the lighting, the method and...
US20180122746 COOLER WITH EMI-LIMITING INDUCTOR  
A power device package includes a dielectric substrate having an upper conductor layer and a lower conductor layer, a semiconductor die coupled to the upper conductor layer of the dielectric...
9957567 Methods relating to DENND1A Variant 2 and polycystic ovary syndrome  
Provided are compositions and methods for use in polycystic ovary syndrome diagnosis (PCOS). The method involves a sample from a subject for a DENND1A Variant 2 mRNA or DENND1 A Variant 2 protein...
US20180110682 FEEDING NIPPLE SYSTEMS FOR CLEFT PALATE OR LIP  
An apparatus including artificial nipple for feeding a baby who has a cleft in its palate region. The artificial nipple includes a palate region to define a region facing the baby's palate during...
9953439 Systems and methods for three-dimensional spiral perfusion imaging  
Some aspects of the present disclosure relate to systems and methods for three-dimensional spiral perfusion imaging. In one embodiment, a method for perfusion imaging of a subject includes...
9951114 Recombinant cancer therapeutic cytokine  
Recombinant therapeutic cytokines (“therakines”) for the treatment of cancer are provided. The recombinant therakines include a truncated region of MDA-7/TL-24 (“M4”) not normally found in nature...