Patents and Patent Applications from University of Vermont


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US20180169178 AUGMENTING THE IMMUNE RESPONSE BY PROMOTING CELL DEATH OF IMMUNE CELLS  
Methods and products for producing an antigen specific immune response are provided. The methods involve administration of a caspase inhibitor to a subject.
US20180140671 COMPOSITIONS AND METHODS FOR CARDIAC TISSUE REPAIR  
The invention features compositions featuring (a) one or more of connective tissue growth factor (CTGF) and human C-terminal CTGF peptide; and (b) one or more of insulin and IGF-1; and methods of...
US20180125930 METHODS AND COMPOSITONS FOR METABOLIC REGULATION  
The invention relates, in part, to methods and compositions that are useful to modulate metabolic function of cells in vivo or in vitro. In some aspects the invention includes methods and/or...
US20180111348 Self-Stressing Engineered Composite Materials, Methods of Self-Stressing Engineered Composite Materials, and Self-Stressing Reinforcement for Same  
Self-stressing engineered composites that include a matrix containing self-stressing reinforcement that is activated by an activator that causes, in situ, the self-stressing reinforcement to...
US20180105887 MOLECULAR PATHOGENESIS OF MICROCARCINOMA OF THE THYROID  
The invention relates, in part, to compounds, compositions, and methods to assess molecular characteristics papillary microcarcinoma (PMC) of the thyroid and indicators of indolent compared to...
9939449 Diagnostic and therapeutic methods and products related to anxiety disorders  
The present disclosure provides methods for diagnosing and treating anxiety disorders in female subjects. Diagnosis and treatment of such anxiety disorders are based, in part, on an analysis of...
9925230 Augmenting the immune response by promoting cell death of immune cells  
Methods and products for producing an antigen specific immune response are provided. The methods involve administration of a caspase inhibitor to a subject.
US20180082385 SYSTEMS AND METHODS FOR RANDOMIZED, PACKET-BASED POWER MANAGEMENT OF CONDITIONALLY-CONTROLLED LOADS AND BI-DIRECTIONAL DISTRIBUTED ENERGY STORAGE SYSTEMS  
The present disclosure provides a distributed and anonymous approach to demand response of an electricity system. The approach conceptualizes energy consumption and production of...
9913864 Compositions and methods for cardiac tissue repair  
The invention features compositions comprising agents having cardiac protective activity isolated from epicardial progenitor cells and derivatives thereof, and methods for the use of such...
US20180064711 METHODS FOR TREATING CRYPTOSPORIDIOSIS USING TRIAZOLOPYRIDAZINES  
Methods for treating or prophylaxis of a Cryptosporidium infection using compositions comprising a structure disclosed herein. Also provided are pharmaceutical compositions and kits for...
9907828 Treatments of oxidative stress conditions  
The present invention generally relates to systems and methods for treating certain oxidative stress conditions. In one aspect, compositions and methods of the invention can be used to treat a...
US20180028599 MCJ AGONISTS AND USES THEREFOR  
The invention relates, in part, to compounds, compositions, and methods useful to treat cancer in cells and subjects. In some aspects the invention includes compounds and methods that increase...
US20180022771 CYMANQUINE COMPOUNDS AND DERIVATIVES THEREOF AND USES THEREOF  
Organometallic compounds comprising a chloroquinoline moiety and uses the compounds. The compounds are, for example, manganese or rhenium complexes of a ligand comprising a chloroquinoline moiety....
US20170367603 CATHETER SYSTEMS AND RELATED METHODS FOR MAPPING, MINIMIZING, AND TREATING CARDIAC FIBRILLATION  
Catheters, systems, and related methods for optimized for mapping, minimizing, and treating cardiac fibrillation in a patient, including an array of at least one stacked electrode pair, each...
US20170343561 DIAGNOSTIC AND THERAPEUTIC METHODS AND PRODUCTS RELATED TO ANXIETY DISORDERS  
The present disclosure provides methods for diagnosing and treating anxiety disorders in female subjects. Diagnosis and treatment of such anxiety disorders are based, in part, on an analysis of...
9804377 Low numerical aperture exclusion imaging  
In accordance with one embodiment of the present invention an apparatus for a low numerical aperture exclusion imaging apparatus is provided. The apparatus may include an electromagnetic...
9783584 Methods and compositions for expressing functional class XIV myosin  
The invention, in part, includes methods and compounds useful to prepare and functional class XIV myosin. Functional class XIV myosin prepared using methods of the invention may be useful to...
9737720 Cardiac pacemaker and uses thereof  
The invention relates to improved cardiac pacemakers and methods of use thereof. In particular the cardiac pacemakers are useful for normalizing heart rates over resting heart rates in order to...
9707271 Methods for enhancing cardiac function with the combination of CTGF and insulin or IGF-1  
The invention features compositions featuring (a) one or more of connective tissue growth factor (CTGF) and human C-terminal CTGF peptide; and (b) one or more of insulin and IGF-1; and methods of...
9706935 Catheter systems and related methods for mapping, minimizing, and treating cardiac fibrillation  
Catheters, systems, and related methods for optimized for mapping, minimizing, and treating cardiac fibrillation in a patient, including an array of at least one stacked electrode pair, each...
9693699 Methods and systems for mapping cardiac fibrillation  
Methods and systems for mapping cardiac fibrillation in a patient include deploying a catheter in the patient's heart, wherein the catheter includes an array of at least one stacked electrode pair...
9689819 Electronic psychrometer and/or humidistat with low temperature and high humidity capability  
The present invention has to do with a method and system for a high precision electronic psychrometer operable at low temperatures and high humidity environments. The electronic psychrometer...
US20170151312 METHODS AND PRODUCTS RELATING TO GSK3ß REGULATION  
The invention relates to methods and compositions for regulation of GSK3β activity. The invention provides phosphorylated GSK3β polypeptides and antibodies that recognize such polypeptides The...
US20170138309 Microfluidic Homogeneous Catalyzation Systems and Methods, and Apparatuses Incorporating Same  
Systems, apparatuses, and methods for generating hot gases based on catalyzation involving flowing catalyst. Catalysis occurs in a flow-type mixing catalyzation channel in which a liquid catalyst...
US20170128517 COVALENT INHIBITORS OF DUAL OXIDASE 1 (DUOX 1)  
The present invention generally relates to inhibitors of DUOX1. In some aspects, an inhibitor may be applied to a subject having or being at risk for asthma or other conditions. The inhibitor may...
US20170121407 OXIDIZED LDL AS A BIOMARKER FOR NEUROLOGICAL COMPLICATIONS OF PREGNANCY  
Methods for diagnosing and treating conditions associated with life-threatening neurological complications are provided. The methods involve in some aspects the identification of oxLDL and LOX-1...
9634732 Apparatus and method for inductive power transfer on an electrified roadway using a rotating secondary inductor  
The invention described herein provides an energy transfer system via a tire based inductor system. By using the tire, the area inside the tire, the tire rim, or the wheel as the inductive pick-up...
9634632 System and method for processing signals to enhance audibility in an MRI environment  
A system for processing signals to enhance patient audibility of a plurality of signals in an MRI environment is provided. The system includes an acoustic measuring device for measuring sound...
US20170079542 CATHETERS, SYSTEMS, AND RELATED METHODS FOR MAPPING, MINIMIZING, AND TREATING CARDIAC FIBRILLATION  
Catheters, systems, and related methods for optimized for mapping, minimizing, and treating cardiac fibrillation in a patient, including an array of at least one stacked electrode pair, each...
9568487 Oxidized LDL as a biomarker for neurological complications of pregnancy  
Methods for diagnosing and treating conditions associated with life-threatening neurological complications are provided. The methods involve in some aspects the identification of oxLDL and LOX-1...
US20160360996 VARIABLE VENTILATION AS A DIAGNOSTIC TOOL FOR ASSESSING LUNG MECHANICAL FUNCTION  
Systems and methods for determining lung recruitment/derecruitment dynamics of an individual are disclosed. The disclosed embodiments advantageously use variable ventilation of the individual to...
US20160325103 CARDIAC PACEMAKER AND USES THEREOF  
The invention relates to improved cardiac pacemakers and methods of use thereof. In particular the cardiac pacemakers are useful for normalizing heart rates over resting heart rates in order to...
US20160324929 METHODS OF TREATING DISEASES ASSOCIATED WITH PPARy  
The invention relates to methods for modulating PPAR-γ activity using relaxin or agonists thereof. The result is wide range of new therapeutic regimens for treating, inhibiting the development of,...
9480375 Aeroacoustic duster  
The invention disclosed herein provides for high particle removal rate and/or heat transfer from surfaces. The device removes particulate matter from a surface using a bounded vortex generated...
US20160311868 METHODS AND COMPOSITIONS FOR EXPRESSING FUNCTIONAL CLASS XIV MYOSIN  
The invention, in part, includes methods and compounds useful to prepare and functional class XIV myosin. Functional class XIV myosin prepared using methods of the invention may be useful to...
9460634 Systems for and methods of digital recording and reproduction of tactile drawings  
Systems and methods of digitally recording and reproducing tactile drawings are disclosed. The method includes moving a stylus over a path on the first tactile drawing medium to form a tactile...
9444049 Methods for forming one or more crystalline layers on a substrate  
A method for forming a crystalline film of a material is provided, including depositing a solution, having a base critical speed separating deposition regimes, on a substrate such that a...
9439577 Non-invasive methods for determining cardiac output  
Cardiac output is measured using a non-invasive method comprised of administering hyperbaric or hypobaric gas to the subject then after a time measuring the resultant changes in central or...
US20160256723 Apparatus and Method for Physical Exercise  
A device and method for exercise are presented. The device includes a first vertical member and a second vertical member, each with adjustable lengths. A first horizontal member is disposed...
US20160242671 METHODS OF PREDICTING AND MONITORING LABOR  
The invention includes, in part, methods and apparatus for determining the status of labor in a pregnant subject. In some embodiments of the invention, organ-level uterine function is determined...
9410878 Portable ultrafine particle sizer (PUPS) apparatus  
The Portable Ultrafine Particle Sizer (PUPS) invention is provided. The PUPS is an instrument which can measure particle number concentration for particle sizes under 200 nanometers in-situ. The...
9409962 Methods and compositions for expressing functional class XIV myosin  
The invention, in part, includes methods and compounds useful to prepare and functional class XIV myosin. Functional class XIV myosin prepared using methods of the invention may be useful to...
US20160221941 SELENOCYSTINE DERIVATIVES, ALPHA-METHYLSELENOCYSTEINE, ALPHA-METHYLSELENOCYSTEINE DERIVATIVES, AND METHODS OF MAKING AND USING SAME  
Provided are selenocysteine derivatives (e.g., deuterium and tritium analogs), α-methylselenocysteine, and α-methylselenocysteine derivatives. These compounds can be incorporated in more complex...
9403401 Thermal eraser for tactile drawings  
A thermal eraser for erasing tactile drawing features from a tactile drawing medium, along with methods of erasing tactile drawing features formed on a tactile drawing medium, are disclosed. The...
9403016 Cardiac pacemaker and uses thereof  
The invention relates to improved cardiac pacemakers and methods of use thereof. In particular the cardiac pacemakers are useful for normalizing heart rates over resting heart rates in order to...
9393288 Methods of treating diseases associated with PPARγ  
The invention relates to methods for modulating PPAR-γ activity using relaxin or agonists thereof. The result is wide range of new therapeutic regimens for treating, inhibiting the development of,...
9335533 Adjustable total internal reflectance microscopy (TIRFM) illuminator apparatus  
A new apparatus and method of delivering light to the hack aperture of a High Numerical Aperture (NA) Microscopy Objective lens for Total Internal Reflectance Microscopy (TIRFM) is provided. The...
9326722 Methods of predicting and monitoring labor  
The invention includes, in part, methods and apparatus for determining the status of labor in a pregnant subject. In some embodiments of the invention, organ-level uterine function is determined...
9282908 Methods and systems for optimizing lesion placement to minimize and treat cardiac fibrillation  
Methods and systems for optimizing lesion placement to treat cardiac fibrillation in a patient include obtaining a map of one or more measurements indicative of a number and distribution of...
US20160067378 DECELLULARIZATION AND RECELLULARIZATION OF WHOLE ORGANS  
The present invention provides systems and methods for the decellularization and recellularization of tissue segments. In certain instances the invention comprises coating or sealing...
Matches 1 - 50 out of 389 1 2 3 4 5 6 7 8 >