Patents and Patent Applications from University of Vermont


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US20190343837 METHODS FOR TREATING CRYPTOSPORIDIOSIS USING TRIAZOLOPYRIDAZINES  
Methods for treating or prophylaxis of a cryptosporidium infection using compositions comprising a structure disclosed herein. Also provided are pharmaceutical compositions and kits for...
10456441 Augmenting the immune response by promoting cell death of immune cells  
Methods and products for producing an antigen specific immune response are provided. The methods involve administration of a caspase inhibitor to a subject.
US20190324415 Packetized Energy Management Control Systems and Methods of Using the Same  
Aspects of the present disclosure include anonymous, asynchronous, and randomized control schemes for distributed energy resources (DERs). Such control schemes may include packetized energy...
US20190314555 Supramolecular Alginate Materials for Biomedical Applications  
The present invention relates to the unexpected discovery of novel hydrogel formulations that allow for the encapsulation and delivery of living cells and/or drugs to a subject in need thereof. In...
US20190302107 HYBRID QUANTUM-CLASSICAL COMPUTING SYSTEM AND METHOD  
Disclosed herein are systems and uses of systems operating between fully quantum coherent and fully classical states. Examples include a hybrid quantum-classical computing system comprising a...
10412906 Sap-collecting devices, systems and methods for sap-producing saplings  
Sap-collecting devices, systems and methods for sap-producing saplings are disclosed. The saplings each have at least one stem, which is cut to form a top end at a reasonable height above ground....
10370395 Cymanquine compounds and derivatives thereof and uses thereof  
Organometallic compounds comprising a chloroquinoline moiety and uses the compounds. The compounds are, for example, manganese or rhenium complexes of a ligand comprising a chloroquinoline moiety....
10363254 Methods for treating cryptosporidiosis using triazolopyridazines  
Methods for treating or prophylaxis of a Cryptosporidium infection using compositions comprising a structure disclosed herein. Also provided are pharmaceutical compositions and kits for...
US20190225661 Compositions and Methods for Vascular Protection Against Reperfusion Injury After Myocardial Ischemia  
As described herein, the present invention features compositions comprising an HGF/IgG complex and methods of using such compositions to reduce ischemic reperfusion injury.
US20190221948 3D TRIPOLAR ANTENNA AND METHOD OF MANUFACTURE  
In various embodiments, a three-dimensional (3D) printed tripolar antenna fabricated through additive manufacturing techniques to match the geometries of various commercial wireless node packages...
10350262 MCJ agonists and uses therefor  
The invention relates, in part, to compounds, compositions, and methods useful to treat cancer in cells and subjects. In some aspects the invention includes contacting a cancer cell with one or...
US20190214820 Systems and Methods For Random-Access Power Management  
Systems and methods for distributing electric energy in discrete power packets of finite duration are presented. Systems may include an aggregator for providing power packets to one or more nodes....
US20190196074 Microscopy Safety Dome  
A laser light containment dome providing increased safety to microscopy users while allowing the microscopy instrument to be used in an effective and efficient manner is provided. The laser light...
US20190127441 METHODS AND COMPOSITIONS FOR REDUCING VIRUS INFECTIVITY  
The invention relates, in part, to compounds, compositions, and methods to reduce infectivity of virus particles and to treat viral infections in subjects.
US20190121109 REFLECTED IMAGE MACROSCOPY SYSTEM  
A multi-plane imaging system for imaging multiple reflection planes of a regular or irregular shaped three-dimensional (3D) specimen having top, side and bottom views simultaneously. The system...
US20190120842 METHODS AND COMPOUNDS FOR DIAGNOSING THREONYL-tRNA SYNTHETASE-ASSOCIATED DISEASES AND CONDITIONS  
The invention includes, in part, methods and compounds for diagnosing diseases and conditions characterized by altered threonyl-tRNA synthetase (TARS) activity, which include, but are not limited...
10256631 Systems and methods for random-access power management using packetization  
Systems and methods for distributing electric energy in discrete power packets of finite duration are presented. Systems may include an aggregator for providing power packets to one or more nodes....
US20190099470 MITOCHONDRIAL ANTIVIRAL-SIGNALING (MAVS) POLYPEPTIDES AND DETECTION AND USE THEREOF  
The invention relates, in part, to compounds, compositions, and methods to assess characteristics of mitochondrial antiviral-signaling (MAVS) polypeptides and also to methods of modulating MAVS...
10239926 Compositions and methods for vascular protection against reperfusion injury after myocardial ischemia  
As described herein, the present invention features compositions comprising an HGF/IgG complex and methods of using such compositions to reduce ischemic reperfusion injury.
US20190083553 MODIFIED ARENAVIRUS  
Provided are modified arenaviruses and populations thereof, wherein the modified arenaviruses include i) an introduced PPXY domain; ii) an increased number of PPXY domains; iii) a substituted...
US20190078086 METHODS AND COMPOSITIONS TO TREAT DRUG-INDUCED DISEASES AND CONDITIONS  
Methods and compounds useful to treat drug-induced diseases and conditions are provided. Methods of administering one or more MCJ-inhibiting compounds to decrease MCJ polypeptide activity in...
10228378 Diagnostic and therapeutic methods and products related to anxiety disorders  
The present disclosure provides methods for diagnosing and treating anxiety disorders in female subjects. Diagnosis and treatment of such anxiety disorders are based, in part, on an analysis of...
US20190062722 METHODS AND COMPOUNDS FOR REDUCING THREONYL-tRNA SYNTHETASE ACTIVITY  
The invention includes, in part, methods and compounds for treating diseases and conditions characterized by elevated threonyl-tRNA synthetase (TARS) activity, which include, but are not limited...
10188302 Methods for dynamic visualization of clinical parameters over time  
Featured is a method for assessing risk of a patient condition. Such a method includes providing criteria that relate predetermined parameters to each other, inputting observations into given...
10175237 Methods and compounds for diagnosing threonyl-tRNA synthetase-associated diseases and conditions  
The invention includes, in part, methods and compounds for diagnosing diseases and conditions characterized by altered threonyl-tRNA synthetase (TARS) activity, which include, but are not limited...
10143718 Covalent inhibitors of dual oxidase 1 (DUOX 1)  
The present invention generally relates to inhibitors of DUOX1. In some aspects, an inhibitor may be applied to a subject having or being at risk for asthma or other conditions. The inhibitor may...
10125358 Methods and compounds for increasing threonyl-tRNA synthetase activity  
The invention includes, in part, methods and compounds for treating diseases and conditions characterized by reduced threonyl-tRNA synthetase (TARS) activity, which include, but are not limited to...
10087435 Methods and compounds for reducing threonyl-tRNA synthetase activity  
The invention includes, in part, methods and compounds for treating diseases and conditions characterized by elevated threonyl-tRNA synthetase (TARS) activity, which include, but are not limited...
US20180238869 USES OF SYSTEMS WITH DEGREES OF FREEDOM POISED BETWEEN FULLY QUANTUM AND FULLY CLASSICAL STATES  
Disclosed herein are systems and uses of systems operating between fully quantum coherent and fully classical states. Such systems operate in what is termed the “Poised realm” and exhibit unique...
US20180237483 Compositions and Methods for Vascular Protection Against Reperfusion Injury After Myocardial Ischemia  
As described herein, the present invention features compositions comprising an HGF/IgG complex and methods of using such compositions to reduce ischemic reperfusion injury.
10052365 Methods and products relating to GSK3β regulation  
The invention relates to methods and compositions for regulation of GSK3β activity. The invention provides phosphorylated GSK3β polypeptides and antibodies that recognize such polypeptides. The...
US20180228847 COMPOSITIONS AND METHODS FOR CARDIAC TISSUE REPAIR  
The invention features compositions comprising agents having cardiac protective activity isolated from epicardial progenitor cells and derivatives thereof, and methods for the use of such...
US20180224452 DETECTION OF GLUTATHIONYLATED PROTEINS  
The present invention, in some aspects, relates to systems and methods for determining oxidized proteins, including glutathionylated proteins such as S-glutathionylated proteins. The systems and...
US20180221436 TREATMENTS OF OXIDATIVE STRESS CONDITIONS  
The present invention generally relates to systems and methods for treating certain oxidative stress conditions. In one aspect, compositions and methods of the invention can be used to treat a...
US20180214457 USE OF CYMANQUINE COMPOUNDS AS ANTIMALARIAL AGENTS  
Organometallic compounds comprising a chloroquinoline moiety for use in the prophylaxis and treatment of malaria. The compounds can be manganese or rhenium complexes of a ligand comprising a...
US20180169178 AUGMENTING THE IMMUNE RESPONSE BY PROMOTING CELL DEATH OF IMMUNE CELLS  
Methods and products for producing an antigen specific immune response are provided. The methods involve administration of a caspase inhibitor to a subject.
US20180140671 COMPOSITIONS AND METHODS FOR CARDIAC TISSUE REPAIR  
The invention features compositions featuring (a) one or more of connective tissue growth factor (CTGF) and human C-terminal CTGF peptide; and (b) one or more of insulin and IGF-1; and methods of...
US20180125930 METHODS AND COMPOSITONS FOR METABOLIC REGULATION  
The invention relates, in part, to methods and compositions that are useful to modulate metabolic function of cells in vivo or in vitro. In some aspects the invention includes methods and/or...
US20180111348 Self-Stressing Engineered Composite Materials, Methods of Self-Stressing Engineered Composite Materials, and Self-Stressing Reinforcement for Same  
Self-stressing engineered composites that include a matrix containing self-stressing reinforcement that is activated by an activator that causes, in situ, the self-stressing reinforcement to...
US20180105887 MOLECULAR PATHOGENESIS OF MICROCARCINOMA OF THE THYROID  
The invention relates, in part, to compounds, compositions, and methods to assess molecular characteristics papillary microcarcinoma (PMC) of the thyroid and indicators of indolent compared to...
9939449 Diagnostic and therapeutic methods and products related to anxiety disorders  
The present disclosure provides methods for diagnosing and treating anxiety disorders in female subjects. Diagnosis and treatment of such anxiety disorders are based, in part, on an analysis of...
9925230 Augmenting the immune response by promoting cell death of immune cells  
Methods and products for producing an antigen specific immune response are provided. The methods involve administration of a caspase inhibitor to a subject.
US20180082385 SYSTEMS AND METHODS FOR RANDOMIZED, PACKET-BASED POWER MANAGEMENT OF CONDITIONALLY-CONTROLLED LOADS AND BI-DIRECTIONAL DISTRIBUTED ENERGY STORAGE SYSTEMS  
The present disclosure provides a distributed and anonymous approach to demand response of an electricity system. The approach conceptualizes energy consumption and production of...
9913864 Compositions and methods for cardiac tissue repair  
The invention features compositions comprising agents having cardiac protective activity isolated from epicardial progenitor cells and derivatives thereof, and methods for the use of such...
US20180064711 METHODS FOR TREATING CRYPTOSPORIDIOSIS USING TRIAZOLOPYRIDAZINES  
Methods for treating or prophylaxis of a Cryptosporidium infection using compositions comprising a structure disclosed herein. Also provided are pharmaceutical compositions and kits for...
9907828 Treatments of oxidative stress conditions  
The present invention generally relates to systems and methods for treating certain oxidative stress conditions. In one aspect, compositions and methods of the invention can be used to treat a...
US20180028599 MCJ AGONISTS AND USES THEREFOR  
The invention relates, in part, to compounds, compositions, and methods useful to treat cancer in cells and subjects. In some aspects the invention includes compounds and methods that increase...
US20180022771 CYMANQUINE COMPOUNDS AND DERIVATIVES THEREOF AND USES THEREOF  
Organometallic compounds comprising a chloroquinoline moiety and uses the compounds. The compounds are, for example, manganese or rhenium complexes of a ligand comprising a chloroquinoline moiety....
US20170367603 CATHETER SYSTEMS AND RELATED METHODS FOR MAPPING, MINIMIZING, AND TREATING CARDIAC FIBRILLATION  
Catheters, systems, and related methods for optimized for mapping, minimizing, and treating cardiac fibrillation in a patient, including an array of at least one stacked electrode pair, each...
US20170343561 DIAGNOSTIC AND THERAPEUTIC METHODS AND PRODUCTS RELATED TO ANXIETY DISORDERS  
The present disclosure provides methods for diagnosing and treating anxiety disorders in female subjects. Diagnosis and treatment of such anxiety disorders are based, in part, on an analysis of...
Matches 1 - 50 out of 424 1 2 3 4 5 6 7 8 9 >