Patents and Patent Applications from University of Tennessee


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US20120128571 CARBONATION OF METAL SILICATES FOR LONG-TERM CO2 SEQUESTRATION  
In a preferred embodiment, the invention relates to a process of sequestering carbon dioxide. The process comprises the steps of: (a) reacting a metal silicate with a caustic alkali-metal hydroxide...
8177950 Thermoresponsive microparticle composite hydrogels for electrophoresis  
Disclosed are thermoresponsive microparticle composite hydrogels comprising poly(N-isopropyl acrylamide) and polyacrylamide, and methods regarding their manufacture and their use. The present...
US20120116195 METHOD AND DEVICE FOR DETECTION OF BIOAVAILABLE DRUG CONCENTRATION IN A FLUID SAMPLE  
The invention relates to a method for the controlled delivery of a drug as a function of bioavailable drug concentration, a sensor device for detecting bioavailable drug concentration, and a...
US20120107393 Pellets for Delivery of Biologically Active Substances  
Pellets are made by combining a direct compression binder and a waxy spheronizing agent. The pellets may further contain additional pharmaceutical ingredients and/or a drug. The pellets may be...
8158654 Pyridine non-classical cannabinoid compounds and related methods of use  
Disclosed are compounds of the formula I: wherein R1, R2, V, W, X, Y and Z can be as defined herein. The compounds can be used in the treatment of disorders mediated by the cannabinoid receptors.
8152895 Production of magnesium metal  
A process of producing magnesium metal includes providing magnesium carbonate, and reacting the magnesium carbonate to produce a magnesium-containing compound and carbon dioxide. The...
US20120084884 STABLY TRANSFORMED FERNS AND RELATED METHODS  
Methods that provide for stable transformation of fern spores and/or protonemata by Agrobacterium- and/or by particle-mediated transformation are disclosed. Also provided are stably transformed,...
8140271 Least-square deconvolution (LSD): a method to resolve DNA mixtures  
Least Square Deconvolution (LSD) uses quantitative allele peak data, for example, allele peak area, allele peak height and optical density, derived/obtained from a sample containing the DNA of more...
US20120059032 1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES EFFECTIVE AS ANTIGLIOMA AGENTS, METHODS OF MAKING, AND THEIR USE  
Disclosed are tetrahydroisoquinoline-derivative compounds effective for killing cancer cells, shrinking tumor size, and treating cancer.
US20120052132 COMPOSITIONS AND METHODS FOR TREATMENT OF BODY WEIGHT CONDITIONS  
A nutritional supplement composition having therapeutically effective amounts of milk minerals including calcium, a protein source including kappa-casein fragment 106-169, and enzyme-inhibiting...
8124771 Pyridine classical cannabinoid compounds and related methods of use  
Disclosed are compounds of the formula I: wherein R1, R2, V, W, X, Y and Z can be as defined herein. The compounds can be used in the treatment of disorders mediated by the cannabinoid receptors.
8114374 Carbonation of metal silicates for long-term CO2 sequestration  
In a preferred embodiment, the invention relates to a process of sequestering carbon dioxide. The process comprises the steps of: (a) reacting a metal silicate with a caustic alkali-metal hydroxide...
8110562 Selective androgen receptor modulators, analogs and derivatives thereof and uses thereof  
This invention provides nuclear hormone receptor binding compounds, compositions comprising the same and methods of uses thereof in treating a variety of diseases or conditions in a subject,...
8110222 Composite material  
A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium...
8092825 Glycan binding proteins as therapeutic targets for retinal disorders and treatment methods based thereon  
Disclosed are novel methods of treatment for retinal diseases and conditions including age-related macular degeneration, genetic-based retinal degenerations and retinal detachment. A novel glycan...
8088828 Treating benign prostate hyperplasia with SARMS  
This invention provides a method of treating, preventing, suppressing, inhibiting or reducing the incidence of benign prostate hyperplasia in a male subject, by administering to the subject a...
8080682 Substituted acylanilides and methods of use thereof  
This invention provides SARM compounds and uses thereof in treating a variety of diseases or conditions in a subject, including, inter alia, a muscle wasting disease and/or disorder or a...
8074585 Systems and methods for fluid dispensing  
Systems and methods are disclosed for dispensing fluids. The systems can include a sensor operable to detect when an object passes a first location as the object moves to a second location. The...
US20110295518 METHODS OF ASSOCIATING AN UNKNOWN BIOLOGICAL SPECIMEN WITH A FAMILY  
The present invention provides at least three methods of predicting whether an unknown biological specimen originates from a member of a particular family. These methods compare DNA profiles from...
8061533 Materials comprising polydienes and hydrophilic polymers and related methods  
Materials prepared from polydienes, such as poly(cyclohexadiene), and hydrophilic polymers, such as poly(alkylene oxide), are described. Methods of making the materials and their use in fuel cell...
US20110278212 SEDIMENT AND DETENTION BASIN DRAINAGE SYSTEM AND METHOD  
A fluid drainage system configured for draining a basin impounding fluid and sediment, solids or the like of varying density and turbidity. The system includes a first conduit and a second conduit...
8060522 Parallel data processing system  
A tree-structured index to multidimensional data is created using naturally occurring patterns and clusters within the data which permit efficient search and retrieval strategies in a database of...
US20110268680 HEAT STABLE PROTEIN INGREDIENTS  
The subject invention pertains to methods of making crosslinked protein-carbohydrate conjugates (CPCCs) and uncrosslinked protein-carbohydrate conjugates (PCCs) that are heat, pH and salt stable....
US20110245372 Rubber-Modified Cementitious Substance and Method of Making the Same  
Rubber-modified cementitious substances and various methods of making such substances or components thereof. One embodiment of the substance includes a mix of cement and composite particles,...
8029657 Parallel plate electrodes for particle concentration or removal  
An AC electro-hydro-dynamic system for aggregating particles immersed in a fluid. The AC electro-hydro-dynamic system utilizes at least one set of parallel plate electrodes each having at least one...
8022078 Pyrimidine classical cannabinoid compounds and related methods of use  
Disclosed are compounds of the formula I: wherein R1, R2, V, W, X, Y and Z can be as defined herein. The compounds can be used in the treatment of disorders mediated by the cannabinoid receptors.
US20110224408 TREATMENT AND PROPHYLAXIS OF AMYLOIDOSIS  
Methods useful for effecting prophylaxis or treatment of amyloidosis, including AA Amyloidosis and AL amyloidosis, by administering peptides comprising neoepitopes, such as AA fragments from a...
US20110218328 TREATMENT AND PROPHYLAXIS OF AMYLOIDOSIS  
Methods useful for effecting prophylaxis or treatment of amyloidosis, including AA Amyloidosis and AL amyloidosis, by administering peptides comprising neoepitopes, such as AA fragments from a...
8013745 Passive microwave assessment of human body core to surface temperature gradients and basal metabolic rate  
A passive microwave thermography apparatus uses passive microwave antennas designed for operation, for example, at WARC protected frequencies of 1.400 to 1.427 GHz and 2.690 to 2.70 GHz (for core...
US20110212554 TRANSPARENT CONDUCTIVE NANO-COMPOSITES  
The present invention, in one embodiment, provides a method of forming an organic electric device that includes providing a plurality of carbon nanostructures; and dispersing the plurality of...
8008348 Treating muscle wasting with selective androgen receptor modulators  
This invention provides: 1) a method of treating a subject suffering from a muscle wasting disorder; 2) a method of preventing a muscle wasting disorder in a subject; 3) a method of treating,...
7994295 Recombinant viruses comprising the membrane-proximal domain of VSV G protein  
Recombinant viruses, isolated nucleic acids and methods of generating same encoding for a Rhabdoviral G stem polypeptide are disclosed. Methods, compounds and compositions for target cell fusion...
7985786 Rubber-modified cementitious substance and method of making the same  
Rubber-modified cementitious substances and various methods of making such substances or components thereof. One embodiment of the substance includes a mix of cement and composite particles,...
7977386 Solid forms of selective androgen receptor modulators  
The present invention relates to solid forms of (S)—N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenox y) -2-hydroxy-2-methylpropanamide and process for producing the same.
7977321 Small interfering RNAs targeting feline herpes virus  
The present application provides polynucleotides, compositions thereof and methods of treating feline herpes virus infections. In certain embodiments, the polynucleotides and compositions thereof...
US20110167523 MATERIALS AND METHODS FOR THE PRODUCTION OF BIODIESEL  
The subject invention provides novel microorganisms comprising polynucleotides and polypeptides encoding a methyltransferase. The subject invention provides novel methods for the production of...
7973213 Antibiotic resistance conferred by a plant ABC transporter gene when expressed in transgenic plants  
The use of selectable marker genes, such as the kanamycin resistance encoding neomycin phosphotransferase (nptII), has been invaluable in transgenic plant production. The subject invention provides...
US20110157550 Adaptive Photoscreening System  
Briefly described, one embodiment of the system, among others, can be implemented as follows. The system includes a computer control system and an environmental light source that is controlled by...
7968721 Large-scale synthesis of selective androgen receptor modulators  
This invention relates to a process for preparing a selective androgen receptor modulator (SARM) compound represented by the structure of formula I: wherein X is O; and T, Z, Y, Q, R and R1 are...
7968603 Solid forms of selective androgen receptor modulators  
The present invention relates to solid forms of (S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy) -2-hydroxy-2-methylpropanamide and process for producing the same.
US20110140296 ROBUST CARBON MONOLITH HAVING HIERARCHICAL POROSITY  
A carbon monolith includes a robust carbon monolith characterized by a skeleton size of at least 100 nm, and a hierarchical pore structure having macropores and mesopores
US20110118272 SPECTINAMIDES AS ANTI-TUBERCULOSIS AGENTS  
Novel 3′-deoxy-3′-acylaminospectinomycin compounds are described. Also described are methods of using the 3′-deoxy-3-acylaminospectinomycin compounds and other spectinomycin analogs in treat...
7945526 Method of organizing and presenting data in a table  
An item is organized and presented by displaying a table, wherein the table displays a plurality of data comprising DNA profile analysis results including an observation characterizing the at least...
7935351 Use of CPG oligodeoxynucleotides to induce angiogenesis  
This disclosure provides a method of inducing production of vascular endothelial growth factor by a cell. The method includes contacting the cell with a CpG oligonucleotide, thereby inducing the...
US20110093208 LEAST-SQUARE DECONVOLUTION (LSD): A METHOD TO RESOLVE DNA MIXTURES  
Least Square Deconvolution (LSD) uses quantitative allele peak data, for example, allele peak area, allele peak height and optical density, derived/obtained from a sample containing the DNA of more...
7928203 Chimeric, humanized, or human antibody 2A4  
Methods useful for effecting prophylaxis or treatment of amyloidosis, including AA Amyloidosis and AL amyloidosis, by administering peptides comprising neoepitopes, such as AA fragments from a...
7919647 Selective androgen receptor modulators and methods of use thereof  
This invention provides a class of androgen receptor targeting agents. The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM).
US20110053773 METHODS OF IMPROVING NUTRITIONAL VALUE OF PLANTS  
The subject application provides methods for the direct or indirect improvement of levels of key phytonutrients and/or stress tolerance in plants. Methods of providing for the improvement in key...
7892516 Robust carbon monolith having hierarchical porosity  
A carbon monolith includes a robust carbon monolith characterized by a skeleton size of at least 100 nm, and a hierarchical pore structure having macropores and mesopores.
US20110038948 Methods of Reducing the Production of Reactive Oxygen Species and Methods of Screening or Identifying Compounds and Compositions that Reduce the Production of Reactive Oxygen Species  
The subject application provides methods of identifying compounds, combinations of compounds, compositions, and/or combinations of compositions that are suitable for reducing the production of...