Patents and Patent Applications from University of Southern California


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US20170301869 ORGANOMETALLIC COMPLEXES AS PHOSPHORESCENT EMITTERS IN ORGANIC LEDS  
Organic light emitting devices are described wherein the emissive layer comprises a host material containing an emissive molecule, which molecule is adapted to luminesce when a voltage is applied...
US20170300599 SYSTEM AND METHOD FOR CALIBRATING MULTI-LEVEL BUILDING ENERGY SIMULATION  
Methods and systems for simulating energy use in a building is described. The method includes generating a building model based on building data associated with the building, the building model...
9791333 Portable polarimetric fiber stress sensor system for visco-elastic and biomimetic material analysis  
An all-optical fiber sensor apparatus includes a light source and an in-line fiber polarizer that polarizes light received from the light source. The in-line fiber polarizer outputs light in a...
9790214 Heteroatom containing deoxyuridine triphosphatase inhibitors  
Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions in a method of treating cancer. The dUTPase inhibitors disclosed...
9789211 Methods and compositions for positron emission tomography myocardial perfusion imaging  
This invention provides compounds and compositions useful as imaging tracers for positron emission tomography myocardial perfusion imaging (PET MPI). Compounds in accordance with embodiments of...
9783526 Control of hypoxia-inducible gene expression with oligooxopiperazine nonpeptidic helix mimetics  
The present invention relates to oligooxopiperazines that mimic helix αB of the C-terminal transactivation domain of HIF-1α. Also disclosed are pharmaceutical compositions containing these...
US20170281756 COMPOSITIONS AND METHODS TO SELECTIVELY BLOCK PAIN INDUCED BY COLD  
Tissue injury prompts the release of a number of proalgesic molecules that induce acute and chronic pain by sensitizing pain-sensing neurons (nociceptors) to heat and mechanical stimuli. In...
9780872 Adaptive optics based simultaneous turbulence compensation of multiple orbital angular momentum beams  
An adaptive optics compensation approach for an OAM multiplexed FSO communication system is described, in which a Gaussian beam is used to probe the turbulence-induced wavefront distortions and...
US20170279739 PREDICTIVE NETWORK SYSTEM AND METHOD  
A proactive networking system and method is disclosed. The network anticipates the user demands in advance and utilizes this predictive ability to reduce the peak to average ratio of the wireless...
US20170273793 ASSEMBLY OF LAYERED MONETITE-CHITOSAN NANOCOMPOSITE AND ITS TRANSITION TO ORGANIZED HYDROXYAPATITE  
A multilayer structure that functions as a bone replacement material includes a plurality of organic matrix layers such that each organic matrix layer includes chitosan and a dicarboxylic acid....
9773986 Copper(I)-carbene complexes and organic electroluminescent devices  
Devices comprising an organic light emitting device are provided. The devices can include an anode; a cathode; and an organic layer, disposed between the anode and the cathode. The organic layer...
9771625 Monoamine oxidase inhibitors and methods for treatment and diagnosis of prostate cancer  
A mechanism of monoamine oxidases (MAOs) driven epithelium-to-mesenchymal transition (EMT) is disclosed. Also disclosed are methods for treating cancer by inhibiting or suppressing MAOs in cancer...
US20170272171 PHASE-SENSITIVE REGENERATION WITHOUT A PHASE-LOCKED LOOP USING BRILLOUIN AMPLIFICATION  
Methods, systems, and apparatus for phase-sensitive regeneration of a signal without a phase-locked loop and using Brillouin amplification. The system for phase-sensitive regeneration includes a...
US20170265755 IGLASS: INFRARED THERMOGRAPHY FOR LEARNING THERMOREGULATION PERFORMANCE  
An infrared thermography based technique is described for monitoring an individual's thermoregulation performance and thermal comfort level through measuring the skin temperature on several points...
9768909 Systems and techniques for orbital angular momentum based reconfigurable switching  
In at least one aspect, a device for Orbital Angular Momentum (OAM) based optical communication includes a first spatial light modulator configured to down-convert a first plurality of...
9768402 Enhanced bulk heterojunction devices prepared by thermal and solvent vapor annealing processes  
A method of preparing a bulk heterojunction organic photovoltaic cell through combinations of thermal and solvent vapor annealing are described. Bulk heterojunction films may prepared by known...
9763825 Implantable oxygen generator and transporter  
An implantable medical device is described. The implantable medical device includes a small molecule generator, a small molecule diffusor, and a cannula that connects the two. The small molecule...
9763570 Optical coherence tomography (OCT) system with phase-sensitive B-scan registration  
This disclosure relates to the field of Optical Coherence Tomography (OCT). This disclosure particularly relates to an OCT system having a configuration that uses a phase sensitive B-scan...
9763569 Optical coherence tomography (OCT) system with improved motion contrast  
This disclosure relates to the field of Optical Coherence Tomography (OCT). This disclosure particularly relates to an OCT system with improved motion contrast. This disclosure particularly...
US20170260592 NEXT GENERATION RNA-SEQUENCING AND LONG NON-CODING RNA IN GLIOBLASTOMA MULTIFORME  
LncRNAs are emerging as important oncogenic drivers in many cancers, but comprehensive, agnostic studies to identify key lncRNAs involved in GBM are lacking. Described herein are new lncRNA...
US20170258810 AGENTS, COMPOSITIONS AND METHODS FOR ENHANCING NEUROLOGICAL FUNCTION  
Neuro-enhancing agents, compositions and methods are disclosed herein. Preferred neuro-enhancing agents of the present invention include progesterone and metabolites of progesterone, such as...
US20170258409 SYNCHRONIZED MULTI-MODULE PULSED ARTERIAL SPIN LABELED MAGNETIC RESONANCE IMAGING  
A magnetic resonance imaging system may include a magnet, gradient coils, an RF pulse transmitter, an RF receiver that receives MR signals from tissue that has been exposed to RF pulses, gradient...
9757420 Gene editing for HIV gene therapy  
The present disclosure is in the field of genome engineering, particularly targeted integration of anti-HIV transgenes into the genome of a cell for the treatment and/or prevention of HIV.
9752247 Multi-layer encapsulated structures  
An electroplating method that includes: a) contacting a first substrate with a first article, which includes a substrate and a conformable mask disposed in a pattern on the substrate; b)...
9750731 Small molecules modulator of epigenetic regulation and their therapeutic applications  
Disclosed are methods and compositions for modulating the function of transcription factors, especially transcription factors that recruit epigenetic regulators (histone modifying enzymes) to...
9746480 Human myeloid derived suppressor cell cancer markers  
Provided herein are methods for determining the presence of cancer (malignant versus benign), monitoring the progression of cancer, monitoring cancer relapse, monitoring the response to cancer...
9746475 Antibody and antibody mimetic for visualization and ablation of endogenous proteins  
Provided are compositions and methods for labeling an endogenous protein, in particular, in a live cell, or for ablating an endogenous or target protein. The compositions relate to a fusion...
9745366 Compositions and methods for the prevention of microbial infections  
This disclosure provides methods and compositions to inhibit or prevent infection of a cell by a bacteria that exports DNABII proteins by administering to a tissue infected with the bacteria an...
9739861 Method for reduced field of view MRI in an inhomogeneous field with rapid outer volume suppression  
An MRI scanner may include one or more gradient waveform generators, gradient amplifiers, gradient coils, an RF waveform generator, an RF amplifier, an RF coil, a superconducting magnet, an RF...
US20170237456 SWALLOW EXERCISER  
A method and system for antenna alignment is provided at a receiving antenna. Geolocation information of the receiving antenna is entered. An auto-programming sequence is initiated to tune to...
US20170232053 DRUG COMBINATIONS AND METHODS TO STIMULATE EMBRYONIC-LIKE REGENERATION TO TREAT DIABETES AND OTHER DISEASES  
Stem cell-based therapies can potentially reverse organ dysfunction and diseases but the removal of impaired tissue and reactivation of the program leading to organ regeneration pose major...
9733402 Reflective color display based on tunable sub-wavelength high contrast gratings  
A sub-pixel unit for a reflective display includes a color filter including a tunable high contrast grating. The tunable high contrast grating reflects light within a first range of wavelengths,...
9732074 Methods, compounds, and compositions for the treatment of angiotensin-related diseases  
Disclosed are small molecule non-peptidic compounds, as well as methods and compositions for the treatment of angiotensin-related diseases and disorders, including cardiovascular diseases,...
US20170217870 Highly Robust Efficient Catalyst For Selective Dehydrogenation Of Neat Glycerol To Lactic Acid  
A catalyst system includes a complex having formula I which advantageously has a sterically protecting N-heterocyclic carbene (NHC) carbene-pyridine ligand to handle harsh reactions conditions...
US20170216364 APOPTOTIC BODIES  
This disclosure relates to apoptotic bodies. The disclosure particularly relates to a composition comprising the apoptotic bodies. The disclosure further relates to preparation of apoptotic bodies...
9721373 Generating instructions for nonverbal movements of a virtual character  
Programs for creating a set of behaviors for lip sync movements and nonverbal communication may include analyzing a character's speaking behavior through the use of acoustic, syntactic, semantic,...
US20170196221 METHOD OF CRYOPRESERVATION OF STEM CELL-DERIVED RETINAL PIGMENT EPITHELIAL CELLS ON POLYMERIC SUBSTRATE  
Disclosed herein are methods and compositions for the cryopreservation of stem cells, such as stem-cell derived retinal pigment epithelial cells, that have been seeded onto and cultured on a...
9700747 Catalytic removal of gas phase contaminants  
Systems and methods for removal of gas phase contaminants may utilize catalytic oxidation. For example, a method may include passing a gas that includes a gas phase contaminant through a catalytic...
US20170189567 Cage-Like Bifunctional Chelators, Copper-64 Radiopharmaceuticals and PET Imaging Using the Same  
Disclosed is a class of versatile Sarcophagine based bifunctional chelators (BFCs) containing a hexa-aza cage for labeling with metals having either imaging, therapeutic or contrast applications...
US20170189530 PHOTOACTIVATED MOLECULES FOR LIGHT INDUCED MODULATION OF THE ACTIVITY OF ELECTRICALLY EXCITABLE CELLS AND METHODS OF USING THE SAME  
Disclosed herein are methods and compositions for the modulation of the activity of electrically excitable cells. In particular, several embodiments relate to the use of photovoltaic compounds...
9693894 MEMS device and method for delivery of therapeutic agents  
Embodiments of an implantable device for delivering a therapeutic agent to a patient include a reservoir configured to contain a liquid comprising the therapeutic agent, and a cannula in fluid...
US20170187060 INEXPENSIVE METAL-FREE ORGANIC REDOX FLOW BATTERY (ORBAT) FOR GRID-SCALE STORAGE  
A flow battery includes a positive electrode, a positive electrode electrolyte, a negative electrode, a negative electrode electrolyte, and a polymer electrolyte membrane interposed between the...
9688724 Methods for limiting development of a skin wound  
The present invention provides methods for limiting development of skin wounds, and also for treatment of one or more of erythemas, blisters, rashes, pruritis, contact dermatitis, psoriasis,...
9687523 Compositions and methods for the treatment of sjörgren's syndrome  
This invention provides a method of inducing a lacrimal acinar cell in a tissue to degrade a secretory vesicle and its content protein or proteins from the trans-Golgi network (TGN) by contacting...
US20170174638 COMPOUNDS AND METHODS FOR INHIBITING VACUOLAR ATPASE  
A compound of Formula II, is provided. R1, R2 and R3 are independently either hydrogen, alkyl, aryl, halogen, alkoxy, nitro, amino or hydroxyl. X is either F, Cl, Br, I or CN. Y is either N or CH....
US20170172967 Benzo Lipoxin Analogues  
Benzolipoxin analogs, methods of their preparation and pharmaceutical compositions containing the compounds are provided. The compounds and compositions are useful in methods for treatment of...
9682105 Methods of promoting wound healing and attenuating contact hypersensitivity with gingiva-derived mesenchymal stem cells  
Disclosed are methods of polarizing macrophages to exhibit M2 phenotype, including introducing an effective amount of gingiva-derived mesenchymal stem cells to an environment comprising a...
9675620 MAO inhibitors and their conjugates as therapeutics for the treatment of brain cancer  
A pharmaceutical composition and method for treating brain cancer are provided. The method includes administering to a patient in need thereof an effective amount of one or more compounds that...
US20170163451 SYSTEMS AND TECHNIQUES FOR COMMUNICATION USING MULTIPLE-INPUT-MULTIPLE-OUTPUT PROCESSING OF ORBITAL ANGULAR MOMENTUM MODES  
A system includes a transmitter having a first transmit device having a first transmit antenna and a first OAM multiplexer designed to receive two input signals and to convert the input signals to...
US20170162876 Coating Particles  
A method includes combining a coating material and an uncoated particulate core material in a solution having a selected ionic strength. The selected ionic strength promotes coating of the...