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US20120129178 |
GENOMIC POLYMORPHISM FOR PREDICTING THERAPEUTIC RESPONSE
The present invention relates to the use of genomic polymorphism to provide individualized therapeutic regimens to treat patients suffering from diseases such as cancer. The invention discloses...
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US20120128701 |
COMPOSITIONS AND METHODS FOR THE REMOVAL OF BIOFILMS
Methods of breaking down a biofilm or inhibiting, preventing or treating a microbial infection that produces a biofilm are disclosed, which involves administration of a polypeptide that has one or...
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US20120128636 |
Gingiva Derived Stem Cell And Its Application In Immunodulation And Reconstruction
The present invention relates to gingiva derived messenchymal stem cells (GMSCs). More specifically, the invention provides compositions and methods of using GMSCs to regulate inflammatory response...
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8183236 |
Compounds with HIV-1 integrase inhibitory activity and use thereof as anti-HIV/AIDS therapeutics
Pharmacophore models to be used in drug design and discovery are provided. An in silico protocol and in vitro assays are presented. Compounds and their pharmaceutically acceptable salts with HIV-1...
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8181540 |
Measurement of sliding friction-induced vibrations for biomimetic tactile sensing
Tactile sensors are disclosed that mimic the human fingertip and its touch receptors. The mechanical components are similar to a fingertip, with a rigid core surrounded by a weakly conductive fluid...
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US20120122946 |
POLYMORPHISMS FOR PREDICTING DISEASE AND TREATMENT OUTCOME
The invention provides compositions and methods for determining the increased risk for recurrence of certain cancers and the likelihood of successful treatment with one or both of chemotherapy and...
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US20120122795 |
ACCELERATED EXTENSION OF AXONS
The present disclosure relates to methods and compositions for promoting the extension of a neural cell by increasing the expression of activity of cofilin in the cell. The increase can be local to...
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US20120121595 |
FRAGMENT OF SECRETED HEAT SHOCK PROTEIN-90ALPHA (Hsp90ALPHA) AS VACCINES OR EPITOPE FOR MONOCLONAL ANTIBODY DRUGS OR TARGET FOR SMALL MOLECULE DRUGS AGAINST A RANGE OF SOLID HUMAN TUMORS
The invention provides methods for treating HIF-1α-overexpressing human tumors, inhibiting HIF-1α-overexpressing tumor invasion and preventing tumor metastasis, and/or promoting tumor p...
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US20120118218 |
Multiplex-Thruster Systems for Delivering Thrusting Flow
Designs and techniques for fluid thrusters and vehicles that are powered by propelling fluids with fluid thrusters. Multiplex-thruster (MT) systems are disclosed that include a single thruster and...
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US20120115965 |
CONVERSION OF CARBON DIOXIDE TO METHANOL USING BI-REFORMING OF METHANE OR NATURAL GAS
The invention provides for a method of forming methanol by combining a mixture of methane, water and carbon dioxide under specific reaction conditions sufficient to form a mixture of hydrogen and...
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US20120114566 |
LIPOXIN ANALOGS AND METHODS FOR THE TREATMENT OF PERIODONTAL DISEASE
This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including...
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US20120109035 |
REVERSIBLE ADHESIVES
This disclosure relates generally to adhesives and particularly to reversible adhesives. This disclosure further relates to generally adhesive articles and particularly to wound dressings...
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US20120108445 |
VEGF AND VEGFR1 GENE EXPRESSION USEFUL FOR CANCER PROGNOSIS
The invention provides compositions and methods for determining the likelihood of tumor recurrence of adjuvant cancer patients following surgical resection.
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US20120108441 |
POLYMORPHISMS IN ANGIOGENESIS PATHWAY GENES ASSOCIATED WITH TUMOR RECURRENCE IN SURGERY TREATED CANCER PATIENTS
This invention provides compositions and methods for determining the likely tumor recurrence of cancer patients after surgical resection. Said methods are based on determining the patient's...
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US20120107309 |
POLYMORPHISM IN K-RAS 3' UNTRANSLATED REGION ASSOCIATED WITH CLINICAL OUTCOMES OF CANCER TREATMENTS INDEPENDENT OF K-RAS MUTATION STATUS
The invention provides compositions and methods for determining the likelihood of response or survival of cancer patients treated with anti-EGFR therapy, topoisomerase inhibitor therapy or...
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US20120107308 |
GENE EXPRESSION LEVELS OF EGFR, VEGFR2, AND ERCC1 ASSOCIATED WITH CLINICAL OUTCOMES OF CHEMOTHERAPY
The invention provides compositions and methods for identifying a cancer patient suitable for anti-VEGF therapy. After determining if a patient is likely to be successfully treated, the invention...
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US20120100997 |
CD133 POLYMORPHISMS AND EXPRESSION PREDICT CLINICAL OUTCOME IN PATIENTS WITH CANCER
The invention provides compositions and methods for aiding in the determination of or determining whether or not a cancer patient is likely to be responsive to a therapy comprising the...
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US20120100135 |
GENETIC POLYMORPHISMS ASSOCIATED WITH CLINICAL OUTCOMES OF TOPOISOMERASE INHIBITOR THERAPY FOR CANCER
The invention provides compositions and methods for determining the likelihood of response or survival of cancer patients treated with topoisomerase inhibitor therapy or anti-EGFR and topoisomerase...
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US20120100134 |
GENETIC VARIANTS IN ANGIOGENESIS PATHWAY ASSOCIATED WITH CLINICAL OUTCOME
The invention provides methods for determining the clinical outcomes for treatment with various treatment regimens available to cancer patients based on genotypes of the patients for genetic...
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US20120098579 |
CHARGE-BASED PHASE LOCKED LOOP CHARGE PUMP
Charge-based charge pumps are described which include a switchable capacitor configured for connection to a voltage source, a ground, and a charge pump output. A first pair of switches include a...
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8164484 |
Detection and classification of running vehicles based on acoustic signatures
A method and apparatus for identifying running vehicles in an area to be monitored using acoustic signature recognition. The apparatus includes an input sensor for capturing an acoustic waveform...
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8163502 |
Method for predicting the risk of disease based on lectin binding
Provided are methods, test devices, and diagnostic kits for predicting, assessing, and diagnosing the risk of a disease using salivary analysis. The methods comprise providing a whole...
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US20120094844 |
GENETIC VARIANTS IN IL-6, P53, MMP-9 AND CXCR PREDICT CLINICAL OUTCOME IN PATIENTS WITH CANCER
The invention provides compositions and methods for determining the likelihood of response or survival of cancer patients treated with anti-VEGF therapy. After determining if a patient is likely to...
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US20120094291 |
FCgamma POLYMORPHISMS FOR PREDICTING DISEASE AND TREATMENT OUTCOME
The invention provides compositions and methods for determining the likelihood of successful treatment with Cetuximab or other equivalent. The methods comprise determining the genomic polymorphism...
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8158972 |
Organic photosensitive optoelectronic devices containing tetra-azaporphyrins
Embodiments of the present invention provide an organic photosensitive optoelectronic device comprising at least one tetra-azaporphyrin compound of formula (I) are disclosed herein.
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US20120089960 |
EXTENSIBLE COLLABORATIVE SOFTWARE MODELING
Multiple architects may concurrently create and modify a model of computer software, each on their own client at a different location. Each change that is made to a model is forwarded to a server...
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US20120082868 |
Floating Microbial Fuel Cells
A microbial fuel cell (MFC) includes a cation exchange membrane defining an anode chamber, an anode positioned in the anode chamber, and a cathode in contact with an exterior of the cation exchange...
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8148509 |
Transgene delivering retrovirus targeting collagen exposed at site of tissue injury
A viral or non-viral vector particle having a modified viral surface protein wherein the viral surface protein is modified to include a targeting polypeptide including a binding region which binds...
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8148124 |
Regulation of gene expression by protein methylation
The invention relates to the cDNA and deduced amino acid sequence of the Coactivator Associated arginine (R) Methyltransferase protein, CARM1. A method is described for the use CARM1 to regulate...
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US20120077685 |
INTRATUMORAL GENE EXPRESSION LEVELS OF TP AND VEGF ARE ASSOCIATED WITH CLINICAL OUTCOMES IN RECTAL CANCER PATIENTS TREATED WITH 5-FLUOROURACIL AND PELVIC RADIATION
The disclosure provides compositions and methods for identifying a cancer patient suitable or not suitable for a therapy that includes administration of a pyrimidine antimetabolite such as...
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US20120076804 |
CANCER TARGETED INNATE IMMUNITY
Provided is a cancer therapeutic agent comprising a cancer targeting molecule linked to a CpG oligodeoxynucleotide. Also provided are methods of reducing the size of a tumor or inhibiting the...
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US20120071397 |
Methods for Hematopoietic Stem Cell Transplantation
The present invention provides methods for treating a subject undergoing hematopoietic stem cell transplantation, methods for increasing a subject's resistance to bacterial or viral infection...
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8139846 |
Verification of integrated circuits against malicious circuit insertions and modifications using non-destructive X-ray microscopy
A method and system for verifying the integrity of integrated circuits (ICs) by detecting the presence of unauthorized circuit insertions or modifications using non-destructive x-ray microscopy is...
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8138380 |
Electrolysis of carbon dioxide in aqueous media to carbon monoxide and hydrogen for production of methanol
An environmentally beneficial method of producing methanol from varied sources of carbon dioxide including flue gases of fossil fuel burning power plants, industrial exhaust gases or the atmosphere...
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US20120063656 |
EFFICIENT MAPPING OF TISSUE PROPERTIES FROM UNREGISTERED DATA WITH LOW SIGNAL-TO-NOISE RATIO
Image processing methods are described that include segmenting boundaries of a region of interest (ROI) and identifying one or more control points, in each of multiple images of the same object,...
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US20120062719 |
Head-Mounted Photometric Facial Performance Capture
A camera may capture a sequence of images of a face while the face changes. A camera support may cause the field of view of the camera to remain substantially fixed with respect to the face,...
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US20120061257 |
CONCENTRIC BIPOLAR ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY TO ASSESS VASCULAR OXIDATIVE STRESS
Concentric bipolar electrode sensors and assemblies provide for and/or facilitate detection and diagnosis of the non-obstructive and pro-inflammatory atherosclerotic lesions in human arteries...
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8134555 |
Acquisition of surface normal maps from spherical gradient illumination
An apparatus for generating a surface normal map of an object may include a plurality of light sources having intensities that are controllable so as to generate one or more gradient illumination...
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8133926 |
Conversion of carbon dioxide to dimethyl ether using bi-reforming of methane or natural gas
The invention provides for a method of forming dimethyl ether by bimolecular dehydration of methanol produced from a mixture of hydrogen and carbon dioxide obtained by reforming of methane, water...
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US20120058470 |
ELECTRICAL WIRING OF POLYNUCLEOTIDES FOR NANOELECTRONIC APPLICATIONS
The present invention relates to incorporation and patterning of polynucleotide molecular wires onto surfaces. In one embodiment, two or more thiol-modified polynucleotide anchors are separately...
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US20120056994 |
SINGLE-SHOT PHOTOMETRIC STEREO BY SPECTRAL MULTIPLEXING
Single-shot photometric stereo techniques are disclosed in which chromaticity is assumed to be a variable. Scene illumination includes three or more spectrally distinct light sources. A scene image...
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US20120056529 |
3-COORDINATE COPPER(I)-CARBENE COMPLEXES
Novel phosphorescent trigonal copper carbene complexes are provided. The complex comprise a carbene ligand coordinated to a three coordinate copper atom. The complex may be used in organic light...
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8131011 |
Human detection and tracking system
A human tracking system for tracking a plurality of humans in motion, in a video of the humans in motion, includes a human detection subsystem, and a combined tracker. The human detection subsystem...
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US20120053337 |
SYNTHESIS OF 2'-Deoxy-2'-[18F]FLUORO-5-METHYL-1-B-D-ARABINOFURANOSYLURACIL (18F-FMAU)
The present invention relates to methods of synthesizing 18F-FMAU. In particular, 18F-FMAU is synthesized using one-pot reaction conditions in the presence of Friedel-Crafts catalysts. The one-pot...
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US20120052554 |
GENE DELIVERY SYSTEM AND METHOD OF USE
A recombinant replication competent retrovirus for gene deliver and gene therapy is provided. The recombinant retrovirus has a heterologous nucleic acid sequence, a sequence encoding a cell- or...
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US20120050606 |
ILLUMINATION SPHERE WITH INTELLIGENT LED LIGHTING UNITS IN SCALABLE DAISY CHAIN WITH INTERCHANGEABLE FILTERS
A controllable lighting system may include a plurality of light source groups, a group controller for each light source group, a master controller, and a network communication system. Each group...
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8126261 |
3D face reconstruction from 2D images
A 3D face reconstruction technique using 2D images, such as photographs of a face, is described. Prior face knowledge or a generic face is used to extract sparse 3D information from the images and...
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8124066 |
Methods of using interleukin-2 mutants with reduced toxicity
Interleukin-2 (IL-2) mutants having reduced toxicity, which include full-length IL-2, truncated forms of IL-2 and forms of IL-2 that are linked to another molecule are disclosed herein. Particular...
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8123706 |
Frequency-based methods, system and apparatus for cavity reconstruction via area-distance profiles
A method, system and apparatus for Resonance-Based Acoustic Reflectometry that uses a hybrid approach. A method of manufacture, system and apparatus for a modified circle system that allows for the...
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US20120045862 |
CO-DEPOSITION METHODS FOR THE FABRICATION OF ORGANIC OPTOELECTRONIC DEVICES
A method for fabricating an OLED by preparing phosphorescent metal complexes in situ is provided. In particular, the method simultaneously synthesizes and deposits copper (I) complexes in an...
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