Patents and Patent Applications from University of Southern California


Match Document Document Title
10022097 Direct patlak estimation from list-mode PET data  
A medical imaging system for reconstructing quantitative dynamic nuclear medicine images of a subject may include a three dimensional positron emission tomography (3D PET) scanner and a data...
US20180199161 RECEIVED SIGNAL STRENGTH TRANSFORMATION METHOD TO ACHIEVE BETTER INDOOR RADIO FREQUENCY LOCALIZATION  
A method for localizing a mobile device in a physical space based on radio signals received from transmitters in the physical space includes a step of transforming a received signal strength...
US20180194740 DEOXYURIDINE TRIPHOSPHATASE INHIBITORS CONTAINING AMINO SULFONYL LINKAGE  
Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
US20180194064 SURFACE PROJECTION TOOL FOR MULTI-AXIS ADDITIVE MANUFACTURING  
Methods, systems, and devices including a light guide tool for multi-axis additive manufacturing. The light guide tool includes a tubular light guide. The tubular light guide may be made from an...
10019516 System and method for fuzzy ontology matching and search across ontologies  
A computer implemented method of matching ontologies is disclosed. The method includes, for each pair of entities of a first ontology and a second ontology, wherein each pair of entities includes...
10015980 Methods and formulations promoting tissue/organ regeneration, longevity and healthspan  
A method includes a step of identifying a subject in need of diet modification; and administering a first diet to the subject for a first time period. The first diet provides 4.5 to 7 kilocalories...
US20180190927 EXCITED STATE MANAGEMENT  
Arrangements and techniques for providing organic emissive layers are provided, in which the emissive layer includes a first dopant having a dissociative energy level. A second dopant in the...
US20180185303 MONOAMINE OXIDASE INHIBITORS AND METHODS FOR TREATMENT AND DIAGNOSIS OF PROSTATE CANCER  
A mechanism of monoamine oxidases (MAOs) driven epithelium-to-mesenchymal transition (EMT) is disclosed. Also disclosed are methods for treating cancer by inhibiting or suppressing MAOs in cancer...
US20180177786 MONOAMINE OXIDASE INHIBITORS AND METHODS FOR TREATMENT AND DIAGNOSIS OF PROSTATE CANCER  
A method of treating prostate cancer in a subject with biochemically recurrent prostate cancer is provided. The method includes administering to a subject in need thereof an effective amount of a...
US20180177729 G PROTEIN-COUPLED RECEPTORS INCORPORATED INTO REHYDRATED POLYMER VESICLES RETAIN FUNCTIONALITY  
A G Protein Coupled Receptor (GPCR) is incorporated in polymeric giant unilamellar protein vesicles (pGUPs). By utilizing an agarose rehydration technique, the GPCR is inserted in the biased,...
10009038 Wideband Nyquist VCO-based analog-to-digital converter  
An analog-to-digital converter may convert an analog signal into digital codes representative of the changing level of the analog signal. An analog high pass filter may receive and continuously...
US20180175297 Screen Printing Systems and Techniques for Creating Thin-Film Transistors Using Separated Carbon Nanotubes  
A method of fabricating a thin film transistor, the method includes applying a first ink containing metallic particles to a first screen mask, and using the first screen mask to deposit the first...
US20180172683 METHODS FOR ANALYZING THE INTERACTION BETWEEN A TARGET PROTEIN AND A LIGAND  
Provided is a method for simultaneously determining both [L]0 and Kd values of a ligand for a target protein. In one embodiment, the present technology involves performing quantitative equilibrium...
US20180171331 METHODS AND DEVICES FOR MICRO-ISOLATION, EXTRACTION, AND/OR ANALYSIS OF MICROSCALE COMPONENTS IN AN ARRAY  
Provided herein are devices and methods for the micro-isolation of biological cellular material. A micro-isolation device described can comprise a photomask that protects regions of interest...
US20180171330 METHODS AND DEVICES FOR MICRO-ISOLATION, EXTRACTION, AND/OR ANALYSIS OF MICROSCALE COMPONENTS IN AN ARRAY  
Provided herein are devices and methods for the micro-isolation of biological cellular material. A micro-isolation device described can comprise a photomask that protects regions of interest...
US20180169409 SMOOTH MUSCLE ELECTRICAL STIMULATION BASED ON ENTRAINMENT OF INTRACELLULAR CALCIUM ION OSCILLATIONS  
Methods, systems, and apparatus for electrically stimulating a smooth muscle. The method includes generating a continuous pulse train signal having pulses and pulse intervals between the pulses,...
US20180168216 COMPOSITIONS AND METHODS FOR MODIFIED NUTRIENT DELIVERY  
This disclosure provides a microencapsulated capsule or microparticle comprising a nutrient-filled core encapsulated in an enteric coating. The microparticles are useful in the treatment of a...
10002214 Host materials and ligands for dopants in organic light emitting diodes  
Compound libraries, systems, methods, and apparatus, including computer program apparatus, are described for implementing techniques for processing data from a combinatorial inquiry to determine...
US20180167703 DATA ENCODING AND CHANNEL HOPPING USING ORBITAL ANGULAR MOMENTUM MODES  
Methods, systems, and devices for data encoding and channel hopping. The system includes a signal source for providing a signal. The system includes an optical switch having an input port and...
US20180161394 Methods and Related Kits for Treating and Regenerating Tooth Pulp and Periapical Tissues in a Mammal  
In one embodiment, a method of regenerating tooth pulp in a mammal is provided. The method comprises removing at least a portion the existing tooth pulp of a mammal and adding amelogenin protein...
US20180161335 METHODS TO TREAT NEUROLOGICAL DISEASES  
Disclosed is a method of treating a subject who has a neurological disease. The neurological disease may be associated with altered C9ORF72 protein activity. In one aspect, the method includes a...
9996798 Traffic prediction using real-world transportation data  
Systems and techniques for enhancing accuracy of traffic prediction include a system of one or more computers operable to receive a request relating to traffic prediction, compare a first...
US20180159171 LITHIUM-ION MIXED CONDUCTOR MEMBRANE IMPROVES THE PERFORMANCE OF LITHIUM-SULFUR BATTERY AND OTHER ENERGY STORAGE DEVICES  
A lithium ion mixed conduction membrane includes an optional polymeric binder and a partially lithiated ion conductive material having lithium ion conductivity and electrical conductivity...
US20180158552 INTERPRETABLE DEEP LEARNING FRAMEWORK FOR MINING AND PREDICTIVE MODELING OF HEALTH CARE DATA  
A method for creating an interpretable model for healthcare predictions includes training, by a deep learning processor, a neural network to predict health information by providing training data,...
9988653 Method and apparatus for CO2 sequestration  
Processes, methods, and apparatus for carbon sequestration utilizing catalysis schemes configured to provide high concentrations of hydrated CO2 in proximity with a sequestration agent are...
9987380 Boron-based dual imaging probes, compositions and methods for rapid aqueous F-18 labeling, and imaging methods using same  
A composition useful as a PET and/or fluorescence imaging probe a compound a compound of Formula I, including salts, hydrates and solvates thereof: wherein R1-R7 may be independently selected from...
9986903 Minimally obstructive compact speculum  
Medical instruments, particularly structurally-adjustable speculums and retractors for obstetrical and gynecological operations, procedures, and examinations, including a minimally obstructive...
US20180148789 METHODS FOR TREATING AND ASSESSING TUMOR INVASION AND METASTASIS  
Provided herein are methods, such as diagnostic methods, for evaluating a tissue sample, such as a biopsy or cytology specimen of a subject to determine a likelihood of metastasis, a risk of tumor...
US20180148508 MASKING CHIMERIC ANTIGEN RECEPTOR T CELLS FOR TUMOR-SPECIFIC ACTIVATION  
The invention is directed to a masked chimeric antigen receptor, comprising: (a) a masking peptide; (b) one or more antigen-specific targeting domains; (c) an extracellular spacer domain; (d) a...
US20180147156 Therapeutic Compositions Comprising Monoterpenes  
This invention provides a compositions for transport of a therapeutic agent. The compositions contain a therapeutic agent and a monoterpene or an analog thereof. In one aspect, the monoterpene is...
US20180146195 METHOD AND DEVICE FOR PROCESSING A VIDEO SIGNAL BY USING AN ADAPTIVE SEPARABLE GRAPH-BASED TRANSFORM  
The present invention provides a method for decoding a video signal using an adaptive separable graph-based transform, comprising the steps of: receiving a transform index for a target block from...
US20180143180 SYSTEM AND METHOD FOR DETERMINING TUMOR INVASIVENESS  
A method of determining invasion potential of a tumor cell includes exposing a tumor cell to an activity sensor; after exposing the tumor cell to the activity sensor, stimulating the tumor cell to...
US20180142213 PANCREATIC STROMAL PROGENITOR CELLS  
This disclosure relates to pancreatic stromal progenitor cells. This disclosure also relates to isolation of pancreatic stromal progenitor cells. This disclosure further relates to a composition...
9974932 Method and sensor for detecting catheter obstruction  
A self-monitoring catheter system may detect an obstruction during use of a catheter. The system may include a catheter with an interior lumen that has one or more ports into the lumen; a first...
US20180136019 FAULT DETECTION SYSTEM UTILIZING DYNAMIC PRINCIPAL COMPONENTS ANALYSIS  
Methods and systems for detecting a fault in a data set from an industrial process are disclosed. One method includes forming a first data matrix at a data processing framework from time-series...
US20180133336 TARGETING MACULA DENSA CELLS AS A NEW THERAPEUTIC APPROACH FOR KIDNEY DISEASE  
There is no specific cure for chronic kidney disease (CKD), which affects one in every ten adults. The unmet medical need has created significant interest in regenerative therapeutic approaches....
9968880 Regenerative absorbents of modified amines on nano-structured supports  
The invention relates to regenerative, solid sorbent for adsorbing carbon dioxide from a gas mixture, with the sorbent including a modified polyamine and a nano-structured solid support. The...
US20180127785 OPTIMIZED GENE EDITING UTILIZING A RECOMBINANT ENDONUCLEASE SYSTEM  
Described herein are methods and compositions for genomic editing. Endonucleases for genomic editing involve inducing breaks in double stranded DNA, for which knock-ins are notoriously inefficient...
9964967 System and method for control performance monitoring  
A method for monitoring a control of a parameter of one or more devices or systems in an oil or gas production site includes receiving process data, the process data being a result of the control...
9962465 Amelogenin-chitosan hydrogel for dentin hypersensitivity  
A method to regrow a protective layer over exposed/demineralized dentin that includes a step of identifying a subject having exposed/demineralized dentin. The demineralized dentin is contacted...
US20180118831 CAR T-CELLS FOR THE TREATMENT OF B7-H4 EXPRESSING SOLID TUMORS  
CAR cells and antibodies targeting human B7-H4 expressed on many human cancers including but not limited to breast ovarian, and renal cancers are described as a new method of cancer treatment. It...
US20180112003 CAR T-CELL THERAPY DIRECTED TO LHR FOR THE TREATMENT OF SOLID TUMORS  
Provided herein are novel anti-LHR chimeric antigen receptor (CAR), cells or compositions comprising the same, vector or plasmid encoding anti-LHR CAR, and methods for producing the same, or using...
US20180104281 HIGH TELMERASE ACTIVITY BONE MARROW MESENCHYMAL STEM CELLS, METHODS OF PRODUCING THE SAME AND PHARMACEUTICALS AND TREATMENT METHODS BASED THEREON  
Disclosed are isolated human bone marrow mesenchymal stem cells having high telomerase activity (tBMMSCs). Also disclosed are isolated human CD34+ bone marrow mesenchymal stem cells. Also...
9944675 Methods for preparing high throughput peptidomimetics, orally bioavailable drugs and compositions containing same  
Provided herein are methods to generate and screen peptides that exhibit drug like stabilities in vitro and in vivo. By selecting for enzyme resistance, Applicants are able to derive peptides that...
9943996 Process planning of meniscus shapes for fabricating smooth surfaces in mask image projection based additive manufacturing  
A system may produce a desired three dimensional object that includes a tank that holds a liquid that solidifies upon exposure to light; a controllable stage that controllably moves within the...
9943509 Methods, compounds, and compositions for the treatment of musculoskeletal diseases  
This invention provides methods, compounds and compositions for the treatment of musculoskeletal disease, muscle dysfunction, muscle-wasting disease or disorder, including hereditary myopathy,...
9941891 Adaptive spur cancellation techniques and multi-phase injection locked TDC for digital phase locked loop circuit  
A digital phase-locked loop includes a digital loop filter, a digitally controllable oscillator (DCO), and an injection-locked calibration-free time-to-digital converter (TDC) having a ring...
9940727 Three-dimensional modeling from wide baseline range scans  
The present disclosure describes systems and techniques relating to generating three dimensional (3D) models from range sensor data. According to an aspect, frames of range scan data captured...
US20180097249 MATERIALS FOR HIGH-PERFORMANCE AQUEOUS ORGANIC REDOX FLOW BATTERIES  
Quinones and related compounds for use in flow batteries are provided. Many of these compounds are found to mitigate the effects of crossover in a flow battery. Other structure for improving...
US20180094012 NICKEL-BASED CATALYSTS FOR C=O REDUCTION AND OXYGEN EVOLUTION  
A compound having formula I that is useful for C═O reduction is provided: wherein: M is a transition metal; X1, X2 are each independently a counterion; and R1, R2, R3 are each independently H,...