Patents and Patent Applications from University of South Florida


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US20120130384 Apparatus for Osteotomy and Graft Preparation  
Surgical tools that increase surgical accuracy for orthopedic procedures involving long bone osteotomy with or without supplementation with allograft or autograft. Two clamps on the operative side...
US20120128551 IONIC LIQUID MEDIATED SOL-GEL SORBENTS  
Ionic liquid (IL)-mediated sol-gel hybrid organic-inorganic materials present enormous potential for effective use in analytical microextraction. One obstacle to materializing this prospect arises...
8184728 Adaptive symbol transition method for OFDM-based cognitive radio systems and method of use  
In accordance with the present invention, a system and method for orthogonal frequency division multiplexing (OFDM) sidelobe suppression is provided. In a particular embodiment an extension is...
8183249 Inhibitors of AKT/PKB with anti-tumor activity  
The subject invention concerns materials and methods for inhibiting the Akt/PKB pathway. In one embodiment, a compound of the invention inhibits kinase activity and/or phosphorylation levels of Akt...
8183082 Fabrication of organic solar array for applications in microelectromechanical systems and others  
A method of fabricating organic solar arrays for application in DC power supplies for electrostatic microelectromechanical systems (MEMS) devices. A solar array with 20 miniature cells (as small as...
US20120122700 MATERIALS AND METHODS FOR DETERMINING SUBTELOMERE DNA SEQUENCE  
The subject invention pertains to methods for rapid and accurate determination of subtelomere DNA sequences. Also provided are kits for determination of subtelomere sequences and uses of...
US20120121531 BIOCOMPOSITE FOR ARTIFICIAL TISSUE DESIGN  
The present invention concerns a biocomposite useful in artificial tissue replacement, methods for its production, and methods of use. The biocomposite can be implanted into humans or animals as an...
8179581 Electrostatically-addressed MEMS array system and method of use  
The present invention provides an improved electrostatic micro actuator array system comprising a plurality of electrostatic micro actuators, each of the micro actuators further comprising at least...
8178507 Method for the modulation of function of transcription factors  
There is provided a method of modulating the function of transcription factor by administering an effective amount of an oligonucleotide containing optimal nucleotide binding sites for the...
8178502 Effective treatment of esophogeal adenocarcinoma using triciribine and related compounds  
The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat esophogeal adenocarcinoma by one or a combination of (i) administering...
US20120115904 COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY  
Compounds of formula I: or formula II: or a pharmaceutically acceptable salt of formula I or formula II, wherein:R1 is H, hydroxyl, alkoxy, acyl, alkyl, cycloalkyl, aryl, or heteroaryl;R2 is methyl...
8175896 Computer systems and methods for selecting subjects for clinical trials  
Computers, computer program products, and methods for identifying a plurality of subjects for a clinical trial are provided. A candidate set of molecular profiles in a stored plurality of molecular...
8169342 Method of providing a destination alert to a transit system rider  
Provided is a detection method used to alert a rider of a transit system that his or her upcoming destination location is approaching. The method detects upcoming transit stops and alerts the...
8165352 Reconstruction of biometric image templates using match scores  
A method of reconstructing biometric face image templates of a face recognition system (FRS) using the match scores or distances provided by the FRS. The match scores represent the distance between...
8163710 Reduction of graft-versus-host disease by modulation of SHIP activity  
Inhibition of dendritic cell function in solid organ grafts or allogeneic bone marrow transplants prior to or during engraftment by blocking SH2-containing inositol phosphatase (SHIP) expression or...
8163418 Method of controlled delivery for use in electrochemical power sources  
A system and method for improving electrochemical power sources through the dispensing, encapsulation and dispersion into galvanic chambers of an electrochemical cell. Features of the method...
US20120093781 HUMAN MAST CELL LINE AND USES THEREOF  
The subject invention pertains to the development of a novel human mast cell line, USF-MC1. USF-MC1 is a mast cell precursor present in human umbilical cord blood (HUCB) that may be sustained in...
8160163 Method for OFDM signal identification and parameter estimation  
Spectrum sensing is one of the most challenging problems in cognitive radio systems. The spectrum of interest needs to be characterized and unused frequencies should be identified for possible...
8158005 Functional composites formed from colloidal polymer particles with photocatalytic metal oxide (MOx) nanoparticles  
Microcomposites comprising titanium dioxide (TiO2) nanoparticles embedded within cross-linked, thermally responsive microgels of poly(N-isopropylacrylamide) are disclosed. Interpenetrating linear...
8153596 Use of SH2 STAT3/STAT1 peptidomimetics as anticancer drugs  
The subject invention concerns compositions and methods for blocking cancer cell growth or proliferation and/or inducing cancer cell death. Compositions of the present invention are peptidomimetics...
8153020 Hydrogen-storing hydride complexes  
A ternary hydrogen storage system having a constant stoichiometric molar ratio of LiNH2:MgH2:LiBH4 of 2:1:1. It was found that the incorporation of MgH2 particles of approximately 10 nm to 20 nm...
8149685 Covert OFDM transmission using cyclic prefix  
Methods for secure OFDM communications include changing the length of OFDM symbols in a pseudo-random fashion by appending a totally random signal to some of the OFDM symbols. An adaptive cyclic...
8148114 Materials and methods for treatment of inflammatory and cell proliferation disorders  
Compositions and methods for treatment of inflammatory and cell proliferation disorders using natriuretic hormone peptide (NP), polynucleotides encoding NP, or agents that reduce the activity of...
US20120077869 METHOD AND COMPOSITION USING A DUAL SPECIFICITY PROTEIN TYROSINE PHOSPHATASE AS AN ANTIMALARIAL DRUG TARGET  
Phosphotyrosine phosphatase (PTP) encoded by PF13_0027 is a desirable drug target for the human malaria parasite Plasmodium falciparum. This PTP is critical for intraerythrocytic parasite...
8145183 On-demand emergency notification system using GPS-equipped devices  
Provided is an emergency locator system adapted for GPS-enabled wireless devices. Global Positioning System (GPS) technology is and Location Based Services (LBS) are used to determine the exact...
8143398 Activity of new N-acylated ciprofloxacin derivatives against faculative intracellular bacteria  
Bartonella species are facultative intracellular pathogens responsible for a range of diseases in animals and in humans. A selection of N-acyl ciprofloxacin analogues, chemically synthesized from...
US20120067529 SHAPE-SHIFTING SURFACES  
Shape-shifting surfaces that retain their effectiveness as physical barriers while undergoing changes in shape. The shape changes include any motion that makes the surface more effective at...
8140256 Dynamic ride matching system  
A ride matching method is disclosed herein. The ride matching method addresses many of the limitations associated with traditional dynamic ride matching applications. The method is unique in its...
8138907 Travel assistant device  
A travel assistant device to help individuals use transit systems. The device is particularly suited to help individuals with special needs (i.e. physical or mental disabilities) successfully...
8137662 Proliferated cell lines and uses thereof  
The subject invention pertains to tumor cell lines useful for increasing the proliferation potential of any human or animal cell in culture, thereby providing immortalized or continuous cell lines...
US20120065456 PREVENTION AND TREATMENT OF ALZHEIMER'S DISEASE THROUGH ELECTROMAGNETIC FIELD EXPOSURE  
The invention includes a method of treating and preventing a neurological disorder, such as Alzheimer's Disease, in a subject in need thereof by positioning an electromagnetic field emitting source...
US20120061029 Variable Screening  
In one embodiment, a variable screen includes a generally flat sheet having a front surface, a back surface, and a plurality of elongated slits that extend through the sheet from the front surface...
8134394 RF microwave circuit and pulse shaping method  
A multi-port circuit and corresponding method for simultaneous shaping of sub-nanosecond pulses (MCS3P). The MCS3P includes a coupled-line coupler, a Schottky detector diode, and circuitry for...
8133736 Methods for detecting or monitoring cancer using LPE as a marker  
A method of detecting a cancer, such as ovarian cancer, in a test subject including (a) determining the amount of a lysophosphatidyl ethanolamine in a sample of a bodily fluid taken from the test...
8133692 Methods of predicting responsiveness to chemotherapeutic agents and selecting treatments  
Methods are provided for predicting responsiveness of cancer cells to chemotherapy by measuring the level of phosphorylated Stat or the level of expression of Survivin in a cancer and comparing the...
8132637 Off-road capable electric wheelchair attachment  
An attachment for an electric wheelchair that enables the electric wheelchair to be used in areas that would not otherwise be possible, e.g., beaches, mud, and tall grass. The attachment is powered...
US20120058109 REELIN RESCUES COGNITIVE FUNCTION  
Disclosed are methods of influencing, and enhancing, cognitive function by increasing, and/or preventing interference with, Reelin levels as well as Reelin signaling. Cognitive function is...
8127967 Volumetric control apparatus for fluid dispensing  
The present invention provides an apparatus for dispensing fluid in preselected volumetric quantities. The apparatus comprises a valve positioned inline with a conduit holding fluid under pressure,...
US20120053911 Gene Signature for the Prediction of Radiation Therapy Response  
Described are mathematical models and method, e.g., computer-implemented methods, for predicting tumor sensitivity to radiation therapy, which can be used, e.g., for selecting a treatment for a...
8127142 Method of authenticating a user on a network  
A method of controlling access to electronic information is provided. The method requires the use of a portable token adapted to read and verify a user's biometric data in order to view encrypted...
US20120039854 Nanoparticle Targeted Drug Delivery to the Lungs Using Extra-Testicular Sertoli Cells  
A method of delivering a compound of interest to the lungs of a subject by the intravenous injection of Sertoli cells loaded with a plurality of chitosan nanoparticles coupled with the compound of...
8115683 Rectenna solar energy harvester  
A rectenna is a combination of an antenna and a rectifier (diode). Because of limitations in nanotechnology fabrication, it has not been possible to develop rectennas that can operate in the...
8114006 Radio guided seed localization of imaged lesions  
A method of removing lesions by implanting a radioactive seed at the location of the lesion, locating the lesion with the radioactive seed, and removing the lesion with the radioactive seed. A kit...
US20120034614 EARLY DETECTION OF PATHOGENS IN BLOOD  
The present invention is a method of extracting infectious pathogens from a volume of blood including the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis...
US20120034186 INDOLINE SCAFFOLD SHP-2 INHIBITORS AND METHOD OF TREATING CANCER  
Protein tyrosine phosphatase (PTP) Shp2 is a non-receptor PTP that involved in cell signaling and regulation of cell proliferation, differentiation, and migration. Shp2 mediates activation of...
8110699 Cobalt-catalyzed asymmetric cyclopropanation of alkenes with α-nitrodiazoacetates  
A process for the cyclopropanation of olefins with a metal porphyrin catalyst and an acceptor/acceptor substituted diazo reagent.
8110678 Antibiotic-bound poly(caprolactone) polymer  
This invention is the design and synthesis of a caprolactone monomer which bears a pendant protected carboxyl group. This monomer has been copolymerized with caprolactone in varying ratios. After...
8110003 Prostheses for spine discs having fusion capability  
The present invention provides both a device and a method. The device is a human made replacement for the soft discs in the spine. A fabric pouch encloses a central hydraulic element made up of...
US20120029067 Polyphenol Proteasome Inhibitors, Synthesis, and Methods of Use  
The present invention relates to synthetic green tea derived polyphenolic compounds, their modes of syntheses, and their use in inhibiting proteasomal activity and in treating cancers. The present...
US20120024790 SEPARATION COLUMN WITH GERMANIA-BASED SOL-GEL STATIONARY PHASE  
The present invention provides sol-gel germania-coated chromatography separation columns with improved stability under extreme pHs and high temperatures. Also provided are methods of preparation...