Patents and Patent Applications from University of South Florida


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10000452 Quinolone-based compounds, formulations, and uses thereof  
Provided herein are quinolone-based compounds that can be used for treatment and/or prevention of malaria and formulations thereof. Also provided herein are methods of treating and/or preventing...
US20180167452 TOOLS AND METHODS FOR DISTRIBUTED SPATIAL CONTROL OF SWARMS VIA MULTIPLEX INFORMATION NETWORKS  
A method and system for distributed spatial control of a formation of vehicles includes receiving at a first formation vehicle via a peer-to-peer communication interface, direction of travel and...
US20180164050 THERMOELECTRIC FLOW CLOAKING VIA METAMATERIALS  
A thermoelectric cloak including an inner region and an external medium. The inner region has a cloaking effect and is simultaneously invisible from both heat and electric charge fluxes; and heat,...
9990333 Systems and methods for synchronizing the kinematics of uncoupled, dissimilar rotational systems  
In one embodiment, a system or method for kinematically synchronizing uncoupled, dissimilar rotational systems pertain to modeling a first rotational system using an equation of motion to obtain a...
US20180152229 LOW COMPLEXITY FLEXIBLE BEAM-WIDTH FOR DIRECTIONAL MODULATION  
Method and system for transmitting a directionally modulated data stream via an antenna array. A first signal processing circuitry receives a data symbol of a first data stream, maps the first...
US20180146973 POWER MORCELLATION IN A PROTECTED ENVIRONMENT  
A power morcellation system, apparatus, and methodology. Structurally, the device includes a sturdy, pliable (e.g., able to be inserted and retracted through a 10-15 mm morcellator port),...
9981126 System and method for controlling the surface charge of a region of tissue  
A system and method for preventing the undesirable dissipation of charge throughout a tissue surface while maintaining the charge density at a desired tissue treatment site. The invention embodies...
9976068 Method of modulated exothermic chemical systems through phase change materials  
The chemical reactions modulation of temperature and dissipate heat through using phase change materials (PCM). Hydration of a mixture composed of encapsulated and/or non-encapsulated oxides such...
9974290 Animal model and method for studying gene-gene interactions  
The invention concerns a non-human animal model useful for sensitively studying gene-gene interactions over a wide genetic background; methods for producing the animal model; and methods for...
US20180139081 CYCLIC PREFIX-ALIGNED GENERALIZED AND N-CONTINUOUS ORTHOGONAL FREQUENCY DIVISION MULTIPLEXING  
A wireless transmit/receive unit (WTRU) may combine an alignment component with an FDM based symbol to produce a signal such that it is aligned to a duration of a CP of the FDM based symbol at a...
US20180132893 LAPAROSCOPIC TOOL WITH OBTURATOR  
A laparoscopic device with obturator. The device facilitates extraction of specimens from a female subject's abdominal cavity through the subject's vagina by also facilitating the suturing of a...
US20180132786 PROSTHESIS AND ORTHOSIS SLIP DETECTION SENSOR AND METHOD OF USE  
A device and method for measuring prosthetic or orthotic slip is presented. An optical sensor device is attached to the prosthesis or orthosis and measures the amount of relative motion between...
9968378 Adaptation sphere saddle  
An improvement of a polyaxial screw head disclosed in the U.S. Pat. No. 8,277,490. A saddle resides within a tulip. The saddle is configured to mate with a rod. An outer set screw engages an inner...
US20180131089 MM-WAVE WIRELESS CHANNEL CONTROL USING SPATIALLY ADAPTIVE ANTENNA ARRAYS  
System and method for determining a position of an antenna array for optimal wireless communication. The system includes a spatially adaptive and beam-steering antenna array configured to control...
US20180127700 Cell Culture Substrate for Rapid Release and Re-Plating  
The invention pertains to devices and methods for rapid release of a patterned tissue module. The invention pertains to a device comprising a substrate and a pattern of shape-memory polymer...
US20180126034 Osteoconductive and Osteoinductive Implant for Augmentation, Stabilization, or Defect Reconstruction  
Aspects of the present invention provide implants for augmentation, stabilization, or defect reconstruction of bone tissue, comprising a scaffold portion structured to provide shape to the...
US20180126013 RADIOTHERAPEUTIC AND COMPANION IMAGING AGENTS TO TARGET MC1R  
The subject matter disclosed herein relates generally to cancer therapy and to anti-cancer compounds and imaging agents. More specifically, the subject matter disclosed herein relates to agents...
9963805 Polypeptide electrospun nanofibrils of defined composition  
Electrospun nanofibrils and methods of preparing the same are provided. The electrospun nanofibrils comprise at least one polypeptide. A polypeptide can be dissolved in a solution, and the...
9962426 Reelin rescues cognitive function  
Disclosed are methods of influencing, and enhancing, cognitive function by increasing, and/or preventing interference with, Reelin levels as well as Reelin signaling. Cognitive function is...
9962379 Inhibitors of the FKBP51 protein from a high-throughput drug screen and methods of use  
The subject invention concerns materials and methods for treating depression, stress disorders, such as PTSD, anxiety disorders, and/or a neurodegenerative disease or condition in a person or...
9956267 Method of treating skeletal dysplasias using vessel dilator  
C-natriuretic peptide (CNP) has been shown to regulate proliferation of mouse and rat osteoblasts. Genetic deletion of CNP results in dwarfism. CNP effects on bone growth involve inhibition of MEK...
US20180115365 INFORMATION BEAMFORMING FOR VISIBLE LIGHT COMMUNICATION  
Examples of information beamforming technology for visible light communication (VLC) systems are provided. A VLC system can include an array of light emitting diode (LED) elements that can emit...
9950307 Metal chelating composites, methods of using composites, and methods of making composites  
Embodiments of the present disclosure provide for composites, methods of making composites, methods of removing a metal from a fluid, and the like.
9949480 N-alkylthio beta-lactams, alkyl-coenzyme A asymmetric disulfides, and aryl-alkyl disulfides as anti-bacterial agents  
The present invention provides N-alkylthio β-lactams and disulfide compounds (e.g., alkyl-coenzyme A asymmetric disulfides or aryl-alkyl disulfides), compositions containing such compounds, and...
US20180104358 MODIFIED UBE3A GENE FOR A GENE THERAPY APPROACH FOR ANGELMAN SYNDROME  
Angelman Syndrome (AS) is a genetic disorder occurring in approximately one in every 15,000 births. It is characterized by severe mental retardation, seizures, difficulty speaking and ataxia. The...
US20180099071 INTRACORPORAL ULTRA HIGH PURITY CALCIUM SULFATE CAST MIXED WITH ANTIMICROBIALS FOR THE TREATMENT OF PENILE IMPLANT INFECTIONS  
The present invention includes a method for treating penile implant infections that uses a synthetic high-purity calcium sulfate mixed with antimicrobials, which is capable of providing prolonged...
US20180098718 ORIENTATION INVARIANT GAIT MATCHING  
Aspects of gait matching are described herein. In one embodiment, a method of gait matching includes identifying a gait cycle timing in a data sequence captured by an inertial sensor, splitting...
9940709 Systems and methods for diagnosing tumors in a subject by performing a quantitative analysis of texture-based features of a tumor object in a radiological image  
An example method for diagnosing tumors in a subject by performing a quantitative analysis of a radiological image can include identifying a region of interest (ROI) in the radiological image,...
9938526 Manganese ion coated nanoparticles for delivery of compositions into the central nervous system by nasal insufflation  
The compositions and methods of the disclosure particularly target the divalent metal transporter expressed on olfactory nerve terminals to transport divalent cation-coated or cation-containing...
9937359 Plasmonic stimulation of electrically excitable biological cells  
A novel method to stimulate electrically active biological cells using visible wavelength light and metallic nanoparticles possessing plasmonic properties is presented herein. Using this...
US20180092916 METHODS OF TREATING DISEASE-INDUCED ATAXIA AND NON-ATAXIC IMBALANCE  
Methods for treatment of disease-induced ataxia and non-ataxic imbalance are disclosed. The methods involve treating a patient with a compound having nicotinic acetylcholine receptor activity.
US20180092896 MATERIALS AND METHODS FOR DIAGNOSIS, PREVENTION AND/OR TREATMENT OF STRESS DISORDERS AND CONDITIONS ASSOCIATED WITH A-BETA PEPTIDE AGGREGATION  
The subject invention concerns materials and methods for treating and/or preventing diseases associated with accumulation of Aβ peptide in neural tissue. The subject invention also concerns...
US20180092751 BONE FUSION SYSTEM  
A method and system for performing bone fusion and/or securing one or more bones, such as adjacent vertebra, are disclosed. The screw includes a threaded distal piece fixedly attached connected to...
9932443 Peptide-based materials  
The subject invention pertains to peptide-based materials comprising cross-linked peptides with random amino acid sequences that are soluble in water or ethanol before crosslinking but insoluble...
US20180085736 METAL CHELATING COMPOSITES, METHODS OF USING COMPOSITES, AND METHODS OF MAKING COMPOSITES  
Embodiments of the present disclosure provide for composites, methods of making composites, methods of removing a metal from a fluid, and the like.
US20180085139 MINIMALLY INVASIVE LAPAROSCOPIC TISSUE REMOVAL DEVICE  
A minimally invasive laparoscopic tissue removal device, namely a morcellator. The device includes, from proximal end to distal end, a handle, handle guard, elongate sheath, and mouth, finally...
9926354 Amyloid precursor protein (APP) based Ã#-secretase inhibitor peptides, and methods of use  
The present invention provides fusion peptides, compositions, methods and kits for treating, reducing the risk of, lessening the severity of, preventing, or delaying the onset of amyloid-related...
US20180078615 USE OF CCL2 TO INHIBIT ABNORMAL UTERINE BLEEDING  
The present invention concerns compositions and methods for inhibition of abnormal uterine bleeding (AUB), such as that associated with use of long-acting progestin-only contraceptives (LAPCs). An...
US20180078595 INHIBITION OF FORMATION OF AMYLOID B-PROTEIN FIBRILS USING CACTUS MUCILAGE EXTRACTS  
Alzheimer' s disease (AD) is the common neurodegenerative disorder characterized by the formation of extraneuronal accumulation of amyloid fibrils and intracellular neurofibrillary tangles of...
9923650 Compact dual-channel transceivers  
In one embodiment, a method for monitoring a structure includes associating a passive sensor with the structure, the sensor being configured to measure a physical parameter of the structure that...
9911540 Piezoelectric-based solar cells  
In one embodiment, a solar cell includes a transparent electrode, a photoactive layer, and an electron transport layer positioned between the transparent electrode and the photoactive layer, the...
US20180057511 ORGANIC ANION LITHIUM IONIC COCRYSTAL COMPOUNDS AND COMPOSITIONS  
A cocrystal having the formula LiX.aM, or a solvate or hydrate thereof, wherein X is a conjugate base of an organic acid, M is a neutral organic molecule, and a is from 0.5 to 4, pharmaceutical...
9901374 Laparoscopic tool with obturator  
A laparoscopic device with obturator. The device facilitates extraction of specimens from a female subject's abdominal cavity through the subject's vagina by also facilitating the suturing of a...
US20180051055 TOLL-LIKE RECEPTOR 2 LIGANDS AND METHODS OF MAKING AND USING THEREOF  
Disclosed are monoacylated Toll-like receptor 2 ligands which can be used in both the development of targeted agents for the imaging and treatment of pancreatic cancer as well as other cancers,...
9896668 Substrate-mimetic AKT inhibitor  
Disclosed herein is a species of peptide and non-peptide inhibitors of Akt, an oncogenic protein. Beginning with a residue of Akt target substrate GSK-3, the functional domains of the GSK-3...
US20180045681 SYSTEM AND METHOD OF MEASURING CELL VIABILITY AND GROWTH  
A novel SH-SAW biosensor capable of non-invasive and touch-free detection of cancer cell viability and growth or proliferation in two-dimensional (2D) and three-dimensional (3D) cell cultures as...
US20180042968 HUMAN CORD BLOOD AS A SOURCE OF NEURAL TISSUE REPAIR OF THE BRAIN AND SPINAL CORD  
The present invention relates to the use of umbilical cord blood cells from a donor or patient to provide neural cells which may be used in transplantation. The isolated cells according to the...
9893529 Coupling dynamics for power systems with iterative discrete decision making architectures  
Various examples are provided that are related to coupling dynamics for, e.g., power systems with iterative discrete decision making architectures. In one example, a method includes determining an...
9889221 Enhancement of photocatalytic effect with surface roughness in photocatalytic reactors  
Photocatalysis is a promising technique for remediation of indoor air pollution. The present invention focuses on the enhancement of the effectiveness of the photocatalytic process by the...
US20180037768 CUTIN-LIKE MATERIALS WITH ADVANCED FUNCTIONALITIES AND METHODS OF MANUFACTURE  
Cutin-based devices, coatings and methods of producing such devices and coatings are presented herein. Cutin-like materials (CLMs) are presented which mimic and adapt coatings found in nature for...