Patents and Patent Applications from University of South Florida


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US20180265442 Myricanol Derivatives and Uses Thereof for Treatment of Neurodegenerative Diseases  
The subject invention pertains to myricanol derivatives, therapeutic compositions, and methods for treatment of neurodegenerative diseases, in particular, neurodegenerative dieses associated with...
D828875 Six-sided die  
10079700 Edge windowing of OFDM based systems  
Various methods and systems are provided for edge windowing of orthogonal frequency division multiplexing (OFDM) systems. In one example, among others, a method includes obtaining an edge...
10076534 Effective treatment of ovarian cancer using triciribine and related compounds  
The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat ovarian cancer by one or a combination of (i) administering triciribine only...
10076229 Endoscopic overtube  
An over-tube was developed for receiving and guiding endoscopic instruments into a patient's anus, through the colon, and into the peritoneum. The over-tube has a flexible sheath adapted for...
10076228 Minimally invasive networked surgical system and method  
A system for performing non-invasive networked medical procedures including a number of in vivo medical devices, a communication path between at least two of the devices, an ex vivo control unit...
US20180262505 SYSTEMS AND METHODS FOR CHALLENGELESS COAUTHENTICATION  
A system and method of authentication that avoids authentication challenges is described. In operation, an authenticator receives a first request to access a resource generated by a requestor and...
US20180262155 THERMAL RECTIFYING ANTENNA COMPLEX (TRAC)  
A method and device to collect and convert thermal energy from the surrounding environments to produce usable electric power. The device includes a rectenna that is preferably a narrow bandwidth...
US20180256697 NON-TOXIGENIC CLOSTRIDIUM DIFFICILE SPORES FOR USE IN ORAL VACCINATION  
Described are non-toxigenic Clostridium difficile strains and spores. Also described are vaccines comprising the Clostridium difficile spores. Further described are methods of preventing or...
US20180256579 METHODS AND COMPOSITIONS FOR TREATING DRUG RESISTANCE IN CANCER  
Disclosed herein are compositions and methods for treating cancer. Further provided herein are compositions and methods for reducing, inhibiting, or preventing resistance of cancer to tyrosine...
10074530 Carbon nanotube anchor for mass spectrometer  
This invention enables a sensitivity enhancement in the detection of molecular compounds. A mass spectrometry analyte support with nanotube anchors are used to concentrate MALDI samples prepared...
US20180253843 SYSTEMS AND METHODS FOR DIAGNOSING TUMORS IN A SUBJECT BY PERFORMING A QUANTITATIVE ANALYSIS OF TEXTURE-BASED FEATURES OF A TUMOR OBJECT IN A RADIOLOGICAL IMAGE  
An example method for diagnosing tumors in a subject by performing a quantitative analysis of a radiological image can include identifying a region of interest (ROI) in the radiological image,...
US20180250341 METHOD OF REPAIRING DAMAGED BLOOD-SPINAL CORD BARRIER (BSCB)  
The disclosure provides methods of administering a composition comprising human bone marrow CD34+ (hBM34+) cells to a mammal in need thereof, whereby vascular damage in the blood-central nervous...
US20180250244 EXO-S-MECAMYLAMINE FORMULATION AND USE IN TREATMENT  
A pharmaceutical composition includes a therapeutically effective amount of exo-S-mecamylamine or a pharmaceutically acceptable salt thereof, substantially free of exo-R-mecamylamine in...
US20180250241 COMPOSITIONS AND METHODS FOR THE TREATMENT OF TAUOPATHIES  
Disclosed herein are compositions and methods for treating tauopathies such as Alzheimer's disease (AD). Also provided herein are methods of reducing or disrupting tau aggregation in a subject,...
US20180250051 BONE FUSION SYSTEN  
A method and system for performing bone fusion and/or securing one or more bones, such as adjacent vertebra, are disclosed. The screws include a threaded tip connected to a main shaft and a...
US20180250050 BONE FUSION SYSTEM  
A method and system for performing bone fusion and/or securing one or more bones, such as adjacent vertebra, are disclosed. The screws include a threaded tip connected to a main shaft and a...
10069459 Solar cells having internal energy storage capacity  
In one embodiment, a solar cell having internal storage capacity includes a working electrode, a counter electrode, an electrolyte provided between the electrodes, and a composite layer of...
10067136 Photoactivatable probes and uses thereof  
Provided herein are pyridyl- and pyrimidyl-containing diazirines that can be photoactivateable probes and formulations thereof. Also provided herein are photoaffinity labels that can include the...
US20180245086 TRANSFECTION VECTOR FOR PATHOGENIC AMOEBAE AND USES THEREOF  
Disclosed herein are expression vectors suitable for transfection in amoebas. The vectors may include a promoter from a protein-encoding gene from an amoeba, a selection marker, and a...
10060891 Continuous acid-free measurements of total alkalinity  
A system and method for the substantially continuous measurement of the total alkalinity of a sample solution, which includes, equilibrating a sample solution and a gas at a chosen CO2 fugacity...
10059740 Integrin interaction inhibitors for the treatment of cancer  
Integrin interaction inhibitors using a beta-turn promoter are described herein. These peptides are useful in treating cancer, such as multiple myeloma, by administering a therapeutically...
10058517 Methods of treating acanthamoeba infection using apocynin  
Described herein are methods of treating an Acanthamoeba infection in a subject in need thereof by administering an amount of apocynin.
US20180238890 METHODS AND MATERIALS FOR DETECTION, DIAGNOSIS AND MANAGEMENT OF OVARIAN CANCER  
The subject invention concerns methods using a panel of proteins to detect, diagnose, and monitor therapy during treatment of ovarian cancer in a female patient. The proteins were identified using...
US20180236028 REELIN RESCUES COGNITIVE FUNCTION  
Disclosed are methods of influencing, and enhancing, cognitive function and memory by increasing, and/or preventing interference with, Reelin levels as well as Reelin signaling. Cognitive function...
10053374 Systems and methods for water desalination and power generation  
In one embodiment, a water desalination and power generation system includes a power generation subsystem, a water desalination subsystem, and an ejector that links the power generation subsystem...
10052309 Bis-cyclic guanidine compound compositions, methods of use and treatment thereof  
The present disclosure provides compositions including a bis-cyclic guanidine compound, pharmaceutical compositions including a bis-cyclic guanidine compound, methods of treatment of a condition...
10052248 Wireless adjustable wheelchair headrest  
An adjustable wheelchair headrest system to provide wheelchair users with the ability to control their headrest without assistance form another individual. Some wheelchair users are unable to...
US20180229822 GAS-INFLATABLE PERSONAL FLOTATION DEVICES  
In one embodiment, a personal flotation device that can be worn by a user includes an inflation system including an inflatable bladder and a gas-generating component, the gas-generating component...
10046165 Magnetic resonant imaging safe stylus  
An implantable magnetic resonant imaging (MRI) safe stylus for biomedical devices is described. In one example, the stylus includes a set of stylus modules. One or more of the stylus modules...
US20180226582 COAXIAL SEMICONDUCTIVE ORGANIC NANOFIBERS AND ELECTROSPINNING FABRICATION THEREOF  
A coaxial nanocomposite including a core, which includes fibers of a first organic polymer, and a shell, which includes fibers of a second organic polymer, the first polymer and the second polymer...
US20180223443 ELECTRODEPOSITION OF Al-Ni ALLOYS AND Al/Ni MULTILAYER STRUCTURES  
A method for electrodepositing aluminum and nickel using a single electrolyte solution includes forming a mixture comprising nickel chloride and an organic halide, adding aluminum chloride to the...
10039785 HUCBC treatment of amyloid-associated disease  
Administration of human umbilical cord blood cells (HUCBC) or HUCBC-derived plasma is used to treat amyloid-based diseases, such as Alzheimer's disease, Huntington's disease, cerebral amyloid...
10038248 Three-dimensionals RFID tags  
In one embodiment, a radio-frequency identification (RFID) tag includes multiple orthogonal substrates, a passive RFID integrated circuit chip mounted to one of the substrates, and a...
10036773 Aging-sensitive recycling sensors for chip authentication  
Various devices, methods and systems are provided for aging-sensitive chip authentication. In one example, among others, a chip includes a reference Schmitt trigger ring oscillator (STRO)...
10034783 Adjustable prosthetic ankles  
In one embodiment, an adjustable prosthetic ankle separate from a prosthetic foot includes an upper coupling member, a lower coupling member that couples with the upper coupling member, and a...
US20180211033 DETECTING THREATS IN BIG DATA PLATFORMS BASED ON CALL TRACE AND MEMORY ACCESS PATTERNS  
A runtime attack can be detected on a big data system while processes are executed on various computing devices. A behavior profile can be maintained for tasks or processes running on different...
10031140 Orthogonal SAW transducers on substrate for simultaneous biofouling removal and biosensing  
Devices and methods for use in removing non-specific binding in a bioassay are disclosed. A substrate can be used with input and output transducers to output surface acoustic waves. The surface...
10030263 Multiplexed RNA qPCR assay  
Described herein are multiplexed RNA, including miRNA, PCR-based assays.
US20180200250 PROTEIN ACYL TRANSFERASE INHIBITORS AND METHODS OF TREATMENT  
Embodiments of the present disclosure include compositions and pharmaceutical compositions that include protein acyl transferases (PAT) inhibitors, methods of treating a condition or disease,...
10027179 Continuous wireless powering of moving biological sensors  
A system and method for continuous wireless monitoring and powering of at least one sensor is presented. The system is generally comprised of at least one sensor, at least one RF transmitter, an...
10022420 Methods of synthesizing γ-AApeptides, γ-AApeptide building blocks, γ-AApeptide libraries, and γ-AApeptide inhibitors of Aβ40 aggregates  
Embodiments of the present disclosure provide for γ-AApeptides, γ-AApeptide building blocks, methods of making γ-AApeptides and libraries of γ-AApeptides, methods of screening the γ-AApeptide...
US20180195037 Three-Dimensional Fibrous Scaffolds for Cell Culture  
Provided herein is a three-dimensional scaffold composition comprising randomly oriented fibers, wherein the fibers comprise a polyethylene glycol-polylactic acid block copolymer (PEG-PLA) and a...
10020410 Solar tiles and arrays  
In one embodiment, a solar tile includes a hollow body including a first half and a second half, the first half including a dark-colored side that is adapted to absorb solar energy and the second...
US20180185439 METHODS AND COMPOSITIONS RELATED TO KRAS INHIBITORS  
Stapled peptides and methods of using them to inhibit the Kras/Raf interaction are disclosed herein.
10014864 Wide operating level shifters  
Aspects of wide operating range level shifter designs are described. One embodiment includes a level shifter configured to receive an input signal in a first voltage domain and generate an output...
10013797 Analysis-suitable geometry from discrete point sets using a mesh-free method  
The present invention includes a method of creating analysis suitable models from discrete point sets. The proposed methodology is completely automated, requiring no human intervention, as...
10011635 Cyclic peptide conjugates and methods of use  
The present invention concerns cyclic compounds, compositions comprising the cyclic compounds, linkers, a method of preparing a carrying agent:cyclic compound adduct, a method for treating...
10010545 Antibiotic compositions and methods of use  
Embodiments of the present disclosure provide for compositions including an antibiotic containing a N-thiolated beta-lactam moiety, pharmaceutical compositions including the antibiotic, methods of...
US20180177763 SMALL MOLECULES THAT MIMIC OR ANTAGONIZE ACTIONS OF GRANULOCYTE COLONY-STIMULATING-FACTOR (G-CSF)  
Described herein are compound for the modulation of the G-CSF receptor. The compounds may act as agonists, antagonists, and/or mixed or partial agonists/antagonists of G-CSF. Further provided...