Patents and Patent Applications from University of South Florida


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D793944 Wiper blade ornament  
9729994 System and method for listener controlled beamforming  
A system and method for providing assistive listening for a plurality of listeners in an environment including a plurality of acoustic sources. A microphone array in combination with an acoustic...
9728241 Non-volatile flip-flop with enhanced-scan capability to sustain sudden power failure  
Non-volatile flip-flops (NVFFs) based circuitries and schemes that incorporate magnetic tunnel junctions (MTJs) are provided to ensure fast data storage and restoration from an intentional or...
US20170219564 THREE-DIMENSIONAL FIBROUS SCAFFOLDS FOR CELL CULTURE  
Provided herein is a three-dimensional scaffold composition comprising randomly oriented fibers, wherein the fibers comprise a polyethylene glycol-polylactic acid block copolymer (PEG-PLA) and a...
US20170216337 COMPOSITIONS INCLUDING TRICIRIBINE AND EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITOR COMPOUNDS OR SALTS THEREOF AND METHODS OF USE THEREOF  
This application relates to combination therapies including triciribine compounds and epidermal growth factor receptor inhibitor compounds, particularly erlotinib-like compounds and compositions...
9722841 Channel-based coding for wireless communications  
Disclosed are techniques for channel-based coding for wireless communications. A transmitter includes circuitry and multiple antennas. The circuitry selects a subset of the antennas, determines a...
9722180 Mask-stack-shift method to fabricate organic solar array by spray  
An all-spray fabrication method for large scale inverted organic solar array is provided. Zinc oxide sol gel solutions and revised layers shorten the fabrication process from 2 days to 5 hours and...
9720599 Magnetic coprocessor and method of use  
A magnetic system for solving a quadratic optimization problem by associating each of a plurality of variables of a quadratic optimization problem with a nanomagnet of a nanomagnet array, driving...
US20170214532 MAGNETIC MEMORY PHYSICALLY UNCLONABLE FUNCTIONS  
A magnetic random access memory (MRAM) physically unclonable function (PUF) device that uses the geometric variations in magnetic memory cells to generate a random PUF response is described...
9716313 Microfluidic beam scanning focal plane arrays  
In some embodiments, a microfluidic beam scanning focal plane array for a beam scanning antenna includes an elongated microfluidic channel that contains an electrically conductive antenna element...
9715760 Analysis-suitable geometry from discrete point sets using a mesh-free method  
The present invention includes a method of creating analysis suitable models from discrete point sets. The proposed methodology is completely automated, requiring no human intervention, as...
9714943 Methods and materials for capture antibody targeted fluorescent in-situ hybridization (CAT-FISH)  
The subject invention concerns materials and methods for detecting a target cell in a population. Methods of the invention comprise internally labeling cells via fluorescence in situ hybridization...
US20170202902 CONJUGATES FOR IMMUNOTHERAPY  
The current invention pertains to a molecular conjugate comprising an antagonist of a cell surface receptor specific to a target cell and an immune effector, such as a T cell modulator, conjugated...
US20170202848 AFOBAZOLE NANOPARTICLES FORMULATION FOR ENHANCED THERAPEUTICS  
A novel nanoparticle drug composition and method of use thereof is presented herein. The nanoparticle drug composition is comprised of at least one nanoparticle carrier, formed from the...
US20170202795 SMALL MOLECULE INHIBITORS OF STAT3 WITH ANTI-TUMOR ACTIVITY  
The present invention concerns compounds, compositions containing these compounds, and methods of using these compounds and compositions as inhibitors of Stat3 signaling, Stat3 dimerization,...
US20170202659 Reversible Anchoring Devices  
In one embodiment, a reversible anchoring device includes a base having a threaded shaft and an internal passage that extends through the base along a longitudinal direction of the base and a cap...
US20170196948 Methods, Antibodies, and Vaccines Utilizing Epitopes of Alpha Synuclein for Treatment of Parkinsons Disease  
The present invention pertains to a dendritic cell-based vaccine against rh-α-Syn, α-synuclein specific peptide antibodies and related vaccines, and methods of treating, preventing, and/or...
9700597 Methods of treating cognitive impairment  
The subject invention concerns materials and methods for treating a person or animal having cognitive impairment. In one embodiment, the method comprises administering an effective amount of one...
9700259 Rapid custom intra-articular ligament reconstruction guide  
The present invention is a method of creating custom surgical guides based on the patient's unique anatomy that can be quickly and accurately applied intra-operatively without navigation are...
US20170189490 METHODS OF TREATING COGNITIVE IMPAIRMENT  
The subject invention concerns materials and methods for treating a person or animal having cognitive impairment. In one embodiment, the method comprises administering an effective amount of one...
US20170188554 ANIMAL MODEL FOR STUDYING COMPLEX HUMAN DISEASES  
The invention concerns a non-human animal model useful for modeling complex human diseases; compositions comprising cell populations from the animal model having different genotypes for the same...
9695262 Molecularly imprinted polymers having affinity for natriuretic peptides  
The present invention concerns molecularly imprinted polymers (MIPs) having an affinity for natriuretic peptides, such as atrial natriuretic peptide (ANP). In some embodiments, the MIP is a...
US20170185697 SYSTEMS AND METHODS FOR DESIGNING KINETIC SHAPES  
In one embodiment, a kinetic shape is designed by determining an applied force to be applied to an object that is to incorporate the kinetic shape, determining a reactive force that is desired to...
US20170181983 EXO-S-MECAMYLAMINE FORMULATION AND USE IN TREATMENT  
A pharmaceutical composition includes a therapeutically effective amount of exo-S-mecamylamine or a pharmaceutically acceptable salt thereof, substantially free of exo-R-mecamylamine in...
9691912 Devices having nanoscale structures and methods for making same  
In one embodiment, a device includes a substrate having a top surface and cavity that defines generally vertical walls, a thin film of material that has been deposited on the walls of the cavity,...
9691554 Microstructured crystalline device in confined space, a dye-sensitized solar cell, and method of preparation thereof  
A method of forming an ordered nanorods array in a confined space is used to form a high surface area device where an ensemble of parallel trenches has micrometer dimensions for the width and...
9687847 Microfluidic platforms for optical biosensing  
In one embodiment, a microfluidic platform for optical biosensing, the platform including an optical substrate, a layer provided on the substrate, and a channel formed within the layer through...
US20170174726 STABILIZED PEPTOID-PEPTIDE HYBRIDS AND USES THEREOF  
The current invention pertains to stabilized peptoids or peptoid-peptide hybrids. The peptoids or peptoid-peptide hybrids are stabilized by side chain-side to side chain linkages and/or backbone...
US20170173307 NOVEL NON-INVASIVE METHOD FOR DIRECT DELIVERY OF THERAPEUTICS TO THE SPINAL CORD IN THE TREATMENT OF SPINAL CORD PATHOLOGY  
Most spinal cord therapies are administered systemically, with only a small portion of the therapeutic reaching the spinal cord. A novel method for delivering therapeutics directly to the spinal...
US20170173216 COLLAGEN SCAFFOLDS, MEDICAL IMPLANTS WITH SAME AND METHODS OF USE  
The subject invention concerns non-degradable three dimensional porous collagen scaffolds and coatings. These scaffolds can be prepared around sensors for implantation into a body. A specific...
US20170173049 WITHACNISTIN COMPOUNDS FOR TREATMENT OF CANCER  
The subject invention pertains to the treatment of tumors and cancerous tissues and the prevention of tumorigenesis and malignant transformation through the modulation of STAT3 intracellular...
US20170172969 METHODS OF SUSTAINING DIETARY KETOSIS AND ITS EFFECTS ON LIPID PROFILE  
The ketogenic diet (KD) has therapeutic implications in many disease states. It was hypothesized ketone precursor supplementation would elevate blood ketone levels to therapeutic ranges (2-7 mM)...
US20170172418 STANDARDIZED ORAL HEALTH ASSESSMENT AND SCORING USING DIGITAL IMAGING  
System and methodology objectively capture clinical data on oral health and provide standardized scoring for quantifying oral health. The process of capturing clinical data is based on use of an...
9684218 Low-cost chromatic devices  
In one embodiment, a chromatic device includes an active layer and an electrolyte layer in contact with the active layer, wherein the active layer has an opaque color that blocks light but changes...
9682124 Methods of treating cognitive impairment  
The subject invention concerns materials and methods for treating a person or animal having cognitive impairment. In one embodiment, the method comprises administering an effective amount of one...
9676807 Metal-organic materials (MOMs) for adsorption of polarizable gases and methods of using MOMs  
Embodiments of the present disclosure provide for multi-component metal-organic materials (MOMs), systems including the MOM, systems for separating components in a gas, methods of separating...
9675714 Graphene based theranostics for tumor targeted drug/gene delivery and imaging  
Disclosed herein are theranostic nanoparticles configured for simultaneous delivery of a diagnostic moiety, drug moiety, and a gene therapy moiety. In one embodiment, the theranostic nanoparticles...
9675577 Compositions and methods for producing elevated and sustained ketosis  
Beta-hydroxybutyrate mineral salts in combination with medium chain fatty acids or an ester thereof such as medium chain triglycerides were used to induce ketosis, achieving blood ketone levels of...
US20170157571 ELECTROSPUN CACTUS MUCILAGE NANOFIBERS  
Novel electrospun nanofibers and nanofibrous membranes, methods of manufacturing the same, and methods of using the same are provided. The nanofibers include a cactus mucilage, such as mucilage...
9673821 Wide operating level shifters  
Aspects of wide operating range level shifter designs are described. One embodiment includes a level shifter configured to receive an input signal in a first voltage domain and generate an output...
9670179 Antibiotic compositions and methods of use  
Embodiments of the present disclosure provide for compositions including an antibiotic containing a N-thiolated beta-lactam moiety, pharmaceutical compositions including the antibiotic, methods of...
9666342 Magneto-dielectric polymer nanocomposites  
In accordance with the present invention, novel superparamagnetic magneto-dielectric polymer nanocomposites are synthesized using a novel process. The tunability of the dielectric/magnetic...
9662351 Plasma and brain pharmacokinetics of previously unexplored lithium salts  
Despite its narrow therapeutic window, lithium is regarded as the gold standard comparator and benchmark treatment for mania. Attempts to find new drugs with similar therapeutic activities have...
US20170145681 SHAPE-MORPHING SPACE FRAME APPARATUS USING UNIT CELL BISTABLE ELEMENTS  
Unit cell bistable elements, and particular arrangements thereof, that can transform or morph a structure from one shape to another. In certain embodiments, the current invention includes unit...
US20170144099 METAL-ORGANIC MATERIALS (MOMS) FOR CO2 ADSORPTION AND METHODS OF USING MOMS  
Embodiments of the present disclosure provide for metal-organic materials (MOMs), systems that exhibit permanent porosity and using hydrophobic MOMs to separate components in a gas, methods of...
US20170143769 HUMAN UMBILICAL CORD BLOOD-DERIVED MONOCYTES FOR TREATMENT OF NEURODEGENERATIVE DISEASES AND DISORDERS  
Human umbilical cord blood-derived monocytes that markedly promote Aβ clearance through heterodimerization of sAPPα with Aβ and resultant sAPPα production for prevention or treatment of...
9659160 System and methods for authentication using multiple devices  
A system and method of authentication using an authenticator computing device and at least two registered user devices is described. In operation, the authenticator computing device receives a...
9656953 Inhibition of cell proliferation  
The disclosed modulators of Rb:Raf-1 interactions are potent, selective disruptors of Rb:Raf-1 binding, with IC50 values ranging from 80 nM to 500 nM. Further, these compounds are surprisingly...
9655914 Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof  
This application relates to combination therapies including triciribine compounds and epidermal growth factor receptor inhibitor compounds, particularly erlotinib-like compounds and compositions...
9655901 Methods of treating Nfa-1 organism infection using allopurinol  
Described herein is allopurinol and pharmaceutical formulations thereof that can be administered to a subject infected with or suspected of being infected with an organism having an Nfa-1 protein...