Patents and Patent Applications from University of South Florida


Match Document Document Title
US20160329202 SYSTEMS AND METHODS FOR BUBBLE BASED ION SOURCES  
The present disclosure describes embodiments directed to a bubble based ion source system comprising an ion source configured to generate a plurality of ions, a heat source positioned above the...
9486626 Passive electric field focus system for in vivo and in vitro applications  
The present invention provides a system and method of directing, focusing, or concentrating electrical charges within a defined electric field so that these charges can be used to exert forces on...
9486522 Compositions including triciribine and trastuzumab and methods of use thereof  
This application relates to combination therapies including triciribine and related compounds and trastuzumab or a salt thereof and compositions with reduced toxicity for the treatment and...
9486492 Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof  
This application relates to combination therapies including triciribine and related compounds and bortezomib and derivatives thereof analogs and compositions with reduced toxicity for the...
9486470 Compositions including triciribine and one or more platinum compounds and methods of use thereof  
This application encompasses combination therapies including triciribine and related compounds and one or more platinum compounds and compositions with reduced toxicity for the treatment and...
US20160322566 METHOD OF MANUFACTURE FOR A PARTIALLY-SPRAYED LAYER ORGANIC SOLAR PHOTOVOLTAIC CELL  
The fabrication and characterization of large scale inverted organic solar array fabricated using all-spray process is disclosed. Solar illumination has been demonstrated to improve transparent...
US20160322093 Non-Volatile Flip-Flop with Enhanced-Scan Capability to Sustain Sudden Power Failure  
Non-volatile flip-flops (NVFFs) based circuitries and schemes that incorporate magnetic tunnel junctions (MTJs) are provided to ensure fast data storage and restoration from an intentional or...
US20160317487 METHODS OF SUSTAINING DIETARY KETOSIS AND ITS EFFECTS ON LIPID PROFILE  
The ketogenic diet (KD) has therapeutic implications in many disease states. It was hypothesized ketone precursor supplementation would elevate blood ketone levels to therapeutic ranges (2-7 mM)...
US20160317271 METHOD OF TREATING PELVIC PROLAPSE USING A SACROCOLPOPEXY/SACROCERVICOPEXY VAGINAL POSITIONING AND MESH RETENTION SYSTEM  
A method of treating pelvic prolapse is presented herein. Vaginal support device contains flat superior and inferior surfaces to facilitate affixing of mesh to vagina. Vaginal support device may...
9485037 Compact dual-channel transceivers  
In one embodiment, a dual-channel transceiver includes two harmonic repeaters each having a receive antenna, a transmit antenna, and a frequency multiplier connected to the antennas that is...
9481972 Systems and methods for splicing pile segments  
In one embodiment, a pile splicing system and method uses a pile segment adapted to form part of a spliced pile, the pile segment including an elongated concrete body having first and second ends,...
9481864 Conversion of non-neuronal cells into neurons  
The subject invention concerns materials and methods for conversion of non-neuronal cells into neurons. The subject invention also concerns methods for screening drugs and other compounds for...
9481821 Method of modulated exothermic chemical systems through phase change materials  
The chemical reactions modulation of temperature and dissipate heat through using phase change materials (PCM). Hydration of a mixture composed of encapsulated and/or non-encapsulated oxides such...
US20160312222 MANGANESE ION COATED NANOPARTICLES FOR DELIVERY OF COMPOSITIONS INTO THE CENTRAL NERVOUS SYSTEM BY NASAL INSUFFLATION  
The compositions and methods of the disclosure particularly target the divalent metal transporter expressed on olfactory nerve terminals to transport divalent cation-coated or cation-containing...
US20160310160 INCISION-LESS LAPAROSCOPIC INSTRUMENT  
A laparoscopic instrument is placed into the abdomen without the creation of a skin incision. The laparoscopic instrument includes a shaft that does not exceed 1.6 mm in diameter. The shaft has a...
9479375 Joint physical layer security and PAPR mitigation in OFDM systems  
Systems and methods for securing orthogonal frequency division multiplexing (OFDM) transmission of data are discussed herein. Transceivers can sense the signal strength of frequencies on an OFDM...
9476025 Ferromagnetic cell and tissue culture microcarriers  
A porous, collagen coated, ferromagnetic cell culture microcarrier, which is suitable for in vitro cell and tissue culture and which facilitates 3D multicellular construct generation. Also...
US20160303165 HUCBC TREATMENT OF AMYLOID-ASSOCIATED DISEASE  
Administration of human umbilical cord blood cells (HUCBC) or HUCBC-derived plasma is used to treat amyloid-based diseases, such as Alzheimer's disease, Huntington's disease, cerebral amyloid...
US20160302398 ANIMAL MODEL AND METHOD FOR STUDYING GENE-GENE INTERACTIONS  
The invention concerns a non-human animal model useful for sensitively studying gene-gene interactions over a wide genetic background; methods for producing the animal model; and methods for...
US20160297790 CYTOTOXIN COMPOUNDS AND METHODS OF ISOLATION  
The present invention concerns groups of compounds derived from tunicates of the Synoicum species, as well as to pharmaceutical compositions comprising these compounds, and uses thereof. Extracts...
9463190 Methods of treating disease-induced ataxia and non-ataxic imbalance  
Methods for treatment of disease-induced ataxia and non-ataxic imbalance are disclosed. The methods involve treating a patient with a compound having nicotinic acetylcholine receptor activity.
US20160287554 Small Molecule Metal-Activated Protein Inhibition  
A cancer treatment comprises the administration of a pro-drug compound identified by an in silico candidate identification screening. The pro-drug candidates are selected from a data base and...
9458086 Compositions and methods for adipocyte modulation  
Modified stilbenoids and formulations thereof are provided. The modified stilbenoids can include one or more amino or amino-alkyl substituents. The formulation can be for the treatment or...
9457040 Effective treatment of esophageal adenocarcinoma using triciribine and related compounds  
The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat esophogeal adenocarcinoma by one or a combination of (i) administering...
US20160280714 POLYHEDRAL CAGE-CONTAINING METALLOPORPHYRIN FRAMEWORKS, METHODS OF MAKING, AND METHODS OF USING  
Embodiments of the present disclosure provide compositions including metal-organic polyhedrons, metalloporphyrin framework structures, methods of making these, methods of using these, and the like.
9453049 Substrate-mimetic Akt inhibitor  
Disclosed herein is a species of peptide and non-peptide inhibitors of Akt, an oncogenic protein. Beginning with a residue of Akt target substrate GSK-3, the functional domains of the GSK-3...
9451890 Integrated vectorcardiogram system and method of use  
An integrated vectorcardiogram (VCG) device having 3 pairs of electrodes placed in three orthogonal directions with the capability to continuously measure the electrical activity of the heart. All...
US20160275678 IMAGE-BASED AUTOMATED MEASUREMENT MODEL TO PREDICT PELVIC ORGAN PROLAPSE  
A system and methodology for the automated localization, extraction, and analysis of MRI-based features with clinical information to improve the diagnosis of pelvic organ prolapse (POP). The...
US20160271213 REELIN RESCUES COGNITIVE FUNCTION  
Disclosed are methods of influencing, and enhancing, cognitive function by increasing, and/or preventing interference with, Reelin levels as well as Reelin signaling. Cognitive function is...
US20160268027 MAGNETO-DIELECTRIC POLYMER NANOCOMPOSITES  
In accordance with the present invention, novel superparamagnetic magneto-dielectric polymer nanocomposites are synthesized using a novel process. The tunability of the dielectric/magnetic...
9443662 Microstructured crystalline device in confined space, a dye-sensitized solar cell, and method of preparation thereof  
A method of forming an ordered nanorods array in a confined space is used to form a high surface area device where an ensemble of parallel trenches has micrometer dimensions for the width and...
9442116 Method of predicting chemotherapeutic responsiveness of cancer  
Disclosed is a method of predicting clinical tumor outcome by providing gene expression from a tumor sample. The method utilizes a novel genetic screen to identify genes that contribute to...
9439978 Multilayered magnetic micelle compositions and methods for their use  
Provided herein are compositions comprising a micelle having a hydrophobic superparmagnetic iron oxide nanoparticle (SPION) core, a first coating comprising a cationic polymer, and a second...
US20160260211 SYSTEMS AND METHODS FOR DIAGNOSING TUMORS IN A SUBJECT BY PERFORMING A QUANTITATIVE ANALYSIS OF TEXTURE-BASED FEATURES OF A TUMOR OBJECT IN A RADIOLOGICAL IMAGE  
An example method for diagnosing tumors in a subject by performing a quantitative analysis of a radiological image can include identifying a region of interest (ROI) in the radiological image,...
US20160258960 DETECTION OF CANCER BY ELEVATED LEVELS OF BCL-2  
The present invention relates to a method for the diagnosis, prognosis, and monitoring of cancer, such as early or late stage ovarian cancer, in a subject by detecting Bcl-2 in a biological sample...
US20160257712 INTEGRIN INTERACTION INHIBITORS FOR THE TREATMENT OF CANCER  
Integrin interaction inhibitors using a beta-turn promoter are described herein. These peptides are useful in treating cancer, such as multiple myeloma, by administering a therapeutically...
9437906 Electrode mesh galvanic cells  
The present invention is directed to the fabrication of thin aluminum anode batteries using a highly reproducible process that enables high volume manufacturing of the galvanic cells. A thin...
9434926 Graphene hydrogel and methods of using the same  
Provided herein are hydrogel compositions containing graphene, chitosan, a polyethylene (glycol) diacrylate (PEGDA). The hydrogel can optionally contain an N-isopropylacrylamide (NIPAM) (TPCG...
9433682 Graphene hydrogel and method for using the same  
Provided herein is a hydrogel composition comprising a graphene, a chitosan, and a polyethylene (glycol) diacrylate (PEGDA) (PCG hydrogel). In some embodiments, the hydrogel further comprises a...
9433635 Effective treatment of ovarian cancer using triciribine and related compounds  
The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat ovarian cancer by one or a combination of (i) administering triciribine only...
9433581 Poly(vinyl benzoate) nanoparticles for molecular delivery  
The present invention comprises poly(vinyl benzoate) nanoparticle suspensions as molecular carriers. These nanoparticles can be formed by nanoprecipitation of poly(vinyl benzoate) in water using...
9428849 Polypeptide electrospun nanofibrils of defined composition  
Electrospun nanofibrils and methods of preparing the same are provided. The electrospun nanofibrils comprise at least one polypeptide. A polypeptide can be dissolved in a solution, and the...
9426010 Adaptive symbol transition method for OFDM-based cognitive radio systems  
Modulated orthogonal frequency division multiplexing (OFDM) subcarriers generate high sidelobes, resulting in adjacent channel interference (ACI). Current sidelobe suppression techniques, such as...
9425397 Method of manufacturing inverted organic solar microarray for applications in microelectromechanical systems  
The fabrication and characterization of large scale inverted organic solar array fabricated using all-spray process is disclosed. Solar illumination has been demonstrated to improve transparent...
9417610 Incoherent digital holographic adaptive optics  
An aberration-compensated image of an object field is created by generating a full-field complex hologram of the object field, generating a guide star complex hologram of a guide star selected...
9416456 Nano-hybrid structured regioregular polyhexylthiophene (RRPHTh) blend films for production of photoelectrochemical energy  
The novel photoelectrochemical nano-hybrid film fabricated by blending regioregular polyhexylthiophene (RRPHTh) with titanium oxide (TiO2), Zinc oxide (ZnO) and nanodiamond (ND) nanoparticles on...
9415298 Modern dice  
The present invention includes a novel and modern numbering system design modernizing the design of gaming pieces, such as dice and dominos, while maintaining the qualities of utility for which...
9414904 Sacrocolpopexy/sacrocervicopexy vaginal positioning and mesh retention system  
A vaginal support device, vaginal positioning system and associated method of treating pelvic prolapse is presented herein. Vaginal support device contains flat superior and inferior surfaces to...
US20160229892 CYCLIC PEPTIDE CONJUGATES AND METHODS OF USE  
The present invention concerns cyclic compounds, compositions comprising the cyclic compounds, linkers, a method of preparing a carrying agent:cyclic compound adduct, a method for treating...
9410956 Micro-RNA profiling in ovarian cancer  
MicroRNAs (miRNAs) represent a novel class of genes that function as negative regulators of gene expression and have recently been implicated in several cancers. However, aberrant miRNA expression...