Patents and Patent Applications from University of South Florida


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9604195 Metal-organic materials (MOMs) for CO2 adsorption and methods of using MOMs  
Embodiments of the present disclosure provide for metal-organic materials (MOMs), systems that exhibit permanent porosity and using hydrophobic MOMs to separate components in a gas, methods of...
9603869 Lithium co-crystals and an additional neuropsychiatric agent for treatment of neuropsychiatric disorders  
The invention concerns methods and compositions for treating a neuropsychiatric disorder, wherein the method comprises administering an effective amount of a co-crystal of lithium to a subject in...
US20170082602 Systems and Methods for Analyzing Liquids  
In one embodiment, an optical spectroscopy probe includes an optical fiber having a distal tip and a microfluidic filtering chamber attached to the distal tip of the optical fiber, the chamber...
US20170081635 TUMOR-INFILTRATING LYMPHOCYTES FOR ADOPTIVE CELL THERAPY  
Disclosed are compositions and methods for ex vivo expansion of tumorinfiltrating lymphocytes for use in adoptive cell therapy (ACT). Also disclosed are compositions and method for identifying an...
US20170081225 Portable Wastewater Treatment Systems  
In one embodiment, a portable wastewater treatment system includes an anaerobic reactor in which organic material within the wastewater can be broken down, a membrane filter that receives...
US20170080007 EFFECTIVE TREATMENT OF ESOPHAGEAL ADENOCARCINOMA USING TRICIRIBINE AND RELATED COMPOUNDS  
The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat esophogeal adenocarcinoma by one or a combination of (i) administering...
9598338 Myricanol derivatives and uses thereof for treatment of neurodegenerative diseases  
The subject invention pertains to myricanol derivatives, therapeutic compositions, and methods for treatment of neurodegenerative diseases, in particular, neurodegenerative diseases associated...
US20170071566 ELECTRONIC CATHETER STETHOSCOPE  
An electronic catheter stethoscope measures and analyzes acoustic fields and dynamic pressure variations in the gaseous or liquid fluid inside a conventional medical catheter that is positioned in...
US20170071496 RADIOLOGICALLY IDENTIFIED TUMOR HABITATS  
Virtually every cancer patient is imaged with CT, PET or MRI. Importantly, such imaging reveals that tumors are complex and heterogeneous, often containing multiple habitats within them. Disclosed...
9593070 Exo-S-mecamylamine formulation and use in treatment  
A pharmaceutical composition includes a therapeutically effective amount of exo-S-mecamylamine or a pharmaceutically acceptable salt thereof, substantially free of exo-R-mecamylamine in...
US20170067005 CONCENTRICALLY BAFFLED REACTORS AND SYSTEMS THAT INCORPORATE THEM  
In one embodiment, a concentrically baffled reactor includes an outer housing that defines an interior space, an inlet through which material can be delivered into the interior space, an outlet...
US20170065643 METHOD OF STEM CELL DELIVERY INTO THE BRAIN DURING CHRONIC DISEASE USING BLOOD BRAIN BARRIER PERMEABILIZERS  
Blood brain barrier (BBB) permeabilizers, such as mannitol, can facilitate the entry of stem cells from the periphery to the stroke brain. It is unknown whether BBB permeation in the chronic stage...
US20170065564 BIS-CYCLIC GUANIDINE COMPOUND COMPOSITIONS, METHODS OF USE AND TREATMENT THEREOF  
The present disclosure provides compositions including a bis-cyclic guanidine compound, pharmaceutical compositions including a bis-cyclic guanidine compound, methods of treatment of a condition...
US20170062072 Physically unclonable function based on domain wall memory and method of use  
A system and method for providing a physically unclonable function (PFU) is described. In operation, the method includes applying a domain wall shift pulse challenge to a plurality of nanowires of...
US20170060417 MAGNETIC COPROCESSOR AND METHOD OF USE  
A magnetic system for solving a quadratic optimization problem by associating each of a plurality of variables of a quadratic optimization problem with a nanomagnet of a nanomagnet array, driving...
US20170058432 Polypeptide Electrospun Nanofibrils of Defined Composition  
Electrospun nanofibrils and methods of preparing the same are provided. The electrospun nanofibrils comprise at least one polypeptide. A polypeptide can be dissolved in a solution, and the...
US20170058264 FORMATION OF MULTICELLULAR TUMOROIDS AND USES THEREOF  
Described herein are compositions and methods of forming multi-cellular tumoroids. Also described herein are methods of using the multi-cellular tumoroids.
US20170058002 GAMMA-AAPEPTIDES WITH POTENT AND BROAD-SPECTRUM ANTIMICROBIAL ACTIVITY  
The present invention is directed to a novel class of antimicrobial agents called γ-AApeptides. The current invention provides various categories of γ-AApeptides, for example, linear γ-AApeptides,...
US20170056337 ANTIBACTERIAL S-HETEROSUBSTITUTED DISULFIDES  
Synthetically-derived S,S-heterodisubstituted disulfides that exhibit potent in vitro antibacterial activity against a variety of bacteria, including Staphylococcus aureus, methicillin-resistant...
9579422 Collagen scaffolds, medical implants with same and methods of use  
The subject invention concerns non-degradable three dimensional porous collagen scaffolds and coatings. These scaffolds can be prepared around sensors for implantation into a body. A specific...
9579180 Method of treating pelvic prolapse using a sacrocolpopexy/sacrocervicopexy vaginal positioning and mesh retention system  
A method of treating pelvic prolapse is presented herein. Vaginal support device contains flat superior and inferior surfaces to facilitate affixing of mesh to vagina. Vaginal support device may...
US20170050946 ANTIMICROBIALS FROM AN EPIGENETICS BASED FUNGAL METABOLITE SCREENING PROGRAM  
Novel antimicrobial compounds and associated methods of development are presented herein.
US20170050029 Magnetic Resonant Imaging Safe Stylus  
An implantable magnetic resonant imaging (MRI) safe stylus for biomedical devices is described. In one example, the stylus includes a set of stylus modules. One or more of the stylus modules...
US20170044690 Polypeptide Electrospun Nanofibrils of Defined Composition  
Electrospun nanofibrils and methods of preparing the same are provided. The electrospun nanofibrils comprise at least one polypeptide. A polypeptide can be dissolved in a solution, and the...
US20170044225 AMYLOID Precursor Protein (APP) Based β-Secretase Inhibitor Peptides, and Methods of Use  
The present invention provides fusion peptides, compositions, methods and kits for treating, reducing the risk of, lessening the severity of, preventing, or delaying the onset of amyloid-related...
US20170042927 EFFECTIVE TREATMENT OF OVARIAN CANCER USING TRICIRIBINE AND RELATED COMPOUNDS  
The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat ovarian cancer by one or a combination of (i) administering triciribine only...
9566011 Systems and methods for diagnosing cardiovascular conditions  
In one embodiment, a cardiovascular condition is diagnosed by recording a vectorcardiogram for a subject under evaluation, comparing the vectorcardiogram with vectorcardiograms of other subjects,...
US20170039892 SYNTHETIC VAGINAL CUFF MODEL AND METHOD OF SIMULATING VAGINAL CUFF CLOSURE  
A vaginal cuff surgical model and methods of manufacture and use thereof. The model includes a body (resembling a vaginal cuff) and appendages (resembling uterosacral ligaments) extending from the...
9556236 Compositions and methods for treating respiratory syncytial virus infection  
Briefly described, embodiments of the present disclosure relate to isolated polypeptides useful for treatment of respiratory syncytial virus, and to methods and compositions for treating...
9556131 Compositions, methods of use, and methods of treatment  
Embodiments of the present disclosure, in one aspect, relate to a beta-lactamase inhibitor, pharmaceutical compositions including a beta-lactamase inhibitor, methods of treatment of a condition...
9555394 Method of making ionic liquid mediated sol-gel sorbents  
Ionic liquid (IL)-mediated sol-gel hybrid organic-inorganic materials present enormous potential for effective use in analytical microextraction. One obstacle to materializing this prospect arises...
9555392 Electrospun cactus mucilage nanofibers  
Novel electrospun nanofibers and nanofibrous membranes, methods of manufacturing the same, and methods of using the same are provided. The nanofibers include a cactus mucilage, such as mucilage...
US20170022540 BIOINK FOR THREE-DIMENSIONAL BIOMATERIAL PRINTING  
A method of creating “bioink” has been proposed, which increases the shelf-life and transportability of biological materials for use in bioprinting applications. The current invention also...
US20170020826 STABILIZATION OF ALCOHOL INTOXICATION-INDUCED CARDIOVASCULAR INSTABILITY  
The present invention concerns use of an agent that increases sphingosine-1-phosphate (S1P) receptor activity, such as S1P, or an S1P receptor agonist, for treatment of alcohol-intoxicated...
9550992 Compositions and methods for modulating myeloid derived suppressor cells  
Provided are methods and compositions for modulating the differentiation of a myeloid derived suppressor cell (MDSC). In particular, described herein are miR-142 polynucleotides and miR-223...
US20170019284 JOINT PHYSICAL LAYER SECURITY AND PAPR MITIGATION IN OFDM SYTEMS  
Systems and methods for securing orthogonal frequency division multiplexing (OFDM) transmission of data are discussed herein. Transceivers can sense the signal strength of frequencies on an OFDM...
US20170018308 MTJ-BASED CONTENT ADDRESSABLE MEMORY  
Embodiments of the subject invention provide a three transistor, two domain-wall-based magnetic tunnel junction CAM cell (3T-2DW-MTJ CAM). A four transistor, two magnetic tunnel junction ternary...
9547940 Systems and methods for providing augmented reality in minimally invasive surgery  
In one embodiment, a method for providing augmented reality in minimally invasive surgery includes capturing pre-operative image data of internal organs of a patient, capturing intra-operative...
9547899 Mobile hemolysis detection in whole blood samples  
A system for hemolysis detection, where the system generally includes—individually or in combination—a containment apparatus for holding the blood sample and a software application for analyzing...
9543013 Magnetic tunnel junction ternary content addressable memory  
A Magnetic Tunnel Junction (MJT) Ternary Content Addressable Memory (TCAM) employing six transistors and exhibiting reduced standby leakage and improved area-efficiency. In the proposed TCAM, data...
9541112 Invisible picture hanging dot  
The present invention is an art hanging system that uses a drywall anchor combined with monofilament to create a nearly invisible ceiling hangar. The monofilament is fed through the low profile...
US20170004868 Robust Slope Detection Technique for STTRAM and MRAM Sensing  
Slope detection systems and methods are provided that monitor magnetic tunnel junction (MTJ) resistance switching. A low-overhead, sample-and-hold circuit can be used. Slope detection techniques...
US20170002317 CONVERSION OF NON-NEURONAL CELLS INTO NEURONS  
The subject invention concerns materials and methods for conversion of non-neuronal cells into neurons. The subject invention also concerns methods for screening drugs and other compounds for...
US20170000785 INHIBITORS OF THE FKBP51 PROTEIN FROM A HIGH-THROUGHPUT DRUG SCREEN AND METHODS OF USE  
The subject invention concerns materials and methods for treating depression, stress disorders, such as PTSD, anxiety disorders, and/or a neurodegenerative disease or condition in a person or...
US20170000754 KETONE SUPPLEMENTS FOR TREATMENT OF ANGELMAN SYNDROME  
The invention concerns a method of treating Angelman Syndrome (AS) in a subject, comprising inducing ketosis in the subject by administering a therapeutically effective amount of a ketone ester,...
US20170000630 Universal Multi-Branch Endograft  
The present invention provides endovascular stent graft conversion devices, systems and related methods that are particularly useful in aortic aneurysm repair, such as, but not limited to,...
US20170000612 OSTEOCONDUCTIVE AND OSTEOINDUCTIVE IMPLANT FOR AUGMENTATION, STABILIZATION, OR DEFECT RECONSTRUCTION  
Aspects of the present invention provide implants for augmentation, stabilization, or defect reconstruction of bone tissue, comprising a scaffold portion structured to provide shape to the...
9533051 Menthol-based nanoparticles for drug delivery  
The subject invention pertains to formulations comprising poly(menthyl acrylate) nanoparticles comprising at least one active ingredient contained in a plurality of hydrophobic carriers and...
US20160375038 HORMONE TREATMENT FOR AGE-RELATED HEARING LOSS-PRESBYCUSIS  
Permanent hearing loss or deafness affects about 15% of people worldwide, about 40 million in the US alone. There are currently no FDA-approved drugs on the market in the US, or anywhere in the...
9531384 Adiabatic dynamic differential logic for differential power analysis resistant secure integrated circuits  
An adiabatic dynamic differential logic circuit is provided for mitigating a differential power analysis (DPA) attack on a secure integrated chip including a plurality of transistors configured to...