Patents and Patent Applications from University of South Florida


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US20160136228 COMPOSITIONS INCLUDING TRICIRIBINE AND BORTEZOMIB AND DERIVATIVES THEREOF AND METHODS OF USE THEREOF  
This application relates to combination therapies including triciribine and related compounds and bortezomib and derivatives thereof analogs and compositions with reduced toxicity for the...
9339574 Compositions and methods for reducing or preventing medical device-related infections  
Provided herein is a method of reducing a microbial infection of a heparinized surface wherein heparin precipitation is reduced as compared to a control. In some embodiments a composition...
9328035 Systems and methods for producing liquid hydrocarbon fuels  
In one embodiment, liquid hydrocarbon fuels are produced in a single reactor using a hybrid catalyst system including a reforming catalyst, a Fischer-Tropsch synthesis (FTS) catalyst, and a porous...
US20160116482 Target Binding Molecules Identified by Kinetic Target-Guided Synthesis  
Methods of identifying target binding molecules by target guided synthesis are provided. The methods include providing two or more fragments capable of reacting to form the target binding molecule...
9325047 Dynamically reconfigurable bandpass filters  
In one embodiment, a dynamically reconfigurable bandpass filter includes a resonator loop and a microfluidic channel proximate to the resonator loop, the channel containing a conductor, wherein...
9324565 Systems and methods for forming contact definitions  
In one embodiment, a method for fabricating thin film tunnel devices includes forming multiple bottom electrodes on a substrate, depositing an insulating layer of material on top of each bottom...
9322508 Systems and methods for applying reinforcement material to existing structures  
In one embodiment, a system for applying reinforcement material to an existing structure includes a work rail adapted to be temporarily secured to a bottom surface of the structure, adhesive...
9321176 Systems and methods for planning a robot grasp based upon a demonstrated grasp  
In one embodiment, planning a robot grasp of an object includes determining a grasp type that would be used by a human being to grasp the object, determining a position and orientation of the...
US20160109776 Metal Sensitized Color Changing Material  
The subject invention pertains to color changeable, film materials comprising a metal substrate layer; a conducting polymer or conducting polymer composite layer; and an electrolyte layer. The...
US20160108108 INFLAMMATORY DISEASE DIAGNOSIS AND METHODS OF TREATMENT USING LIPOPOLYSACCHARIDES-RESPONSIVE BEIGE-LIKE ANCHOR  
Anti-cytokine therapy has revolutionized immunological disease treatment, but is not always effective and subject to treatment resistance as the cytokine cascade is highly redundant and multiple...
US20160106997 PREVENTION AND TREATMENT OF BRAIN DISEASES AND DISORDERS RELATED TO ABNORMAL PROTEIN AGGREGATION THROUGH ELECTROMAGNETIC FIELD TREATMENT  
A method of treating and preventing a neurological disorder, such as Alzheimer's disease, in a subject in need thereof by positioning an electromagnetic field emitting source proximal to the...
US20160106767 USE OF PKC-IOTA INHIBITORS FOR THE TREATMENT OF BREAST CANCER  
The subject invention pertains to uses of PKC-iota inhibitors for treatment of breast cancer. In one embodiment, the subject invention provides novel uses of 1H-imidazole-4-carboxamide,...
9319253 Edge windowing of OFDM based systems  
Various methods and systems are provided for edge windowing of orthogonal frequency division multiplexing (OFDM) systems. In one example, among others, a method includes obtaining an edge...
9318632 Bare quantum dots superlattice photonic devices  
Manipulation of the passivation ligands of colloidal quantum dots and use in QD electronics. A multi-step electrostatic process is described which creates bare QDs, followed by the formation of QD...
9314375 Method for auto-regulation of intraocular pressure  
A method for controlling intraocular eye pressure via fluid exchange in the body is presented. The method may comprise providing a system to sense and regulate pressure, then implanting the system...
9314103 Sling-back chair  
The Sling-Back Chair is a new hammock hybrid chair. The chair is a cross between a lounge style chair and a hammock. The chair can be optioned for interior or exterior, with personalization...
9308210 Method for modulating canonical Wnt pathway using folate and inositol  
The canonical Wnt signaling pathway is implicated in wound healing. Administration of a composition having myo-inositol and folic acid upregulates fibronectin and provides the greatest protection...
US20160100414 SUPERPOSED SIGNALING FOR BANDWIDTH EFFICIENCY  
Systems, methods and instrumentalities are disclosed for superposed signaling for bandwidth efficiency in wireless communications. Homogeneous and heterogeneous signals may be superposed on the...
9301965 Method of treating ovarian cancer using a PKC inhibitor  
A method of treating ovarian cancer by administering a PKC inhibitor is presented herein. It was found that administering a PKC inhibitor, such as ACPD or ICA-1, to ovarian cancer cells inhibited...
US20160089344 NANOPARTICLE TARGETED DRUG DELIVERY TO THE LUNGS USING EXTRA-TESTICULAR SERTOLI CELLS  
A method of delivering a compound of interest to the lungs of a subject by the intravenous injection of Sertoli cells loaded with a plurality of chitosan nanoparticles coupled with the compound of...
9297995 Automatic stereological analysis of biological tissue including section thickness determination  
Systems and methods are provided for automatic determination of slice thickness of an image stack in a computerized stereology system, as well as automatic quantification of biological objects of...
9297816 Devices and methods for measuring blood coagulation  
In one embodiment, a device for measuring blood coagulation includes a substrate having a surface, an optical waveguide provided on the surface of the substrate, the waveguide having a tip, and...
9295302 Gait-altering shoes  
In one embodiment, a gait-altering shoe includes a frame adapted to support a user's foot and at least one wheel that supports the frame above a walking surface, the wheel having a radius that...
9291507 Differential capacitive readout system and method for infrared imaging  
An IR imaging system comprising microelectromechanical systems (MEMS) differential capacitive infrared sensors within a sensor array formed on a monolithic integrated circuit substrate, or flip...
9289421 Methods and compositions for reducing serum levels of immunoglobulin E (IgE)  
The present disclosure provides methods and pharmaceutical compositions for reducing the serum level of immunoglobulin IgE in an animal or human subject. It has been found that reducing or...
9286687 System and method for estimating the magnetization states of a nanomagnet array  
A system and method for image-processing that will facilitate automatically analyzing and estimating atomic force microscopy (AFM) images and magnetic force microscopy (MFM) images of fabricated...
US20160068503 (-)-EPIGALLOCATECHIN GALLATE DERIVATIVES FOR INHIBITING PROTEASOME  
A method of reducing tumor cell growth, the method including administering an effective amount of a compound having the formula:
US20160067207 COMPOSITIONS AND METHODS FOR PRODUCING ELEVATED AND SUSTAINED KETOSIS  
Beta-hydroxybutyrate mineral salts in combination with medium chain fatty acids or an ester thereof such as medium chain triglycerides were used to induce ketosis, achieving blood ketone levels of...
9277912 Systems and methods for ankle syndesmosis fixation  
In one embodiment, a fixation system includes an anchor adapted to be implanted within a first bone, a washer adapted to be associated with a second bone that is to be secured to the first bone,...
9276556 Micromechanical devices based on piezoelectric resonators  
In some embodiments, a micromechanical filter includes multiple subfilters, each subfilter comprising multiple piezoelectric resonators mechanically coupled in series, wherein the subfilters are...
9273762 Four-linkage backpack relocator  
A device to help an individual with a disability carry his or her bag or storage unit on their wheelchair or other mobility device, without requiring a large space to deploy the storage and...
US20160053319 MICRO-RNAS MODULATING IMMUNITY AND INFLAMMATION  
MicroRNAs are shown to be up- and/or down-regulated in inflammation and immune cells using a mouse model of asthma and regulatory T cells as source of RNA, respectively. Modulating the expression...
US20160052941 ORGANIC ANION LITHIUM IONIC COCRYSTAL COMPOUNDS AND COMPOSITIONS  
A cocrystal having the formula LiX.aM, or a solvate or hydrate thereof, wherein X is a conjugate base of an organic acid, M is a neutral organic molecule, and a is from 0.5 to 4, pharmaceutical...
9267822 Systems and methods for evaluating coupled components  
In some embodiments, a system for evaluating coupled components includes a first diffraction grating provided on a first component, a second diffraction grating provided on a second component, a...
9265783 Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof  
This application relates to combination therapies including triciribine compounds and epidermal growth factor receptor inhibitor compounds, particularly erlotinib-like compounds and compositions...
9265685 Compliant bimanual rehabilitation device and method of use thereof  
A compliant bimanual rehabilitation system. The device allows for the user or operator's hands to be coupled with a variety of coupling stiffnesses and in a variety of symmetry modes, leading to...
9263803 Mechanically reconfigurable antennas  
In some embodiments, a mechanically reconfigurable antenna includes a patch antenna, one or more parasitic patches, and a radially foldable linkage associated with the patch antenna that can be...
9260271 Knot tying devices  
In some embodiments, a knot tying device includes a body that defines a wheel slot and inner passages that lead to the wheel slot and a wheel that fits and can be rotated within the wheel slot,...
US20160043314 METHOD OF MANUFACTURING INVERTED ORGANIC SOLAR MICROARRAY FOR APPLICATIONS IN MICROELECTROMECHANICAL SYSTEMS  
The fabrication and characterization of large scale inverted organic solar array fabricated using all-spray process is disclosed. Solar illumination has been demonstrated to improve transparent...
US20160030483 MATERIALS AND METHODS FOR TREATING ALLERGIC AND INFLAMMATORY CONDITIONS  
The subject invention provides for the utilization of bone-marrow derived stem cells in the treatment of allergic and inflammatory diseases. In one embodiment, the invention provides for treatment...
US20160030388 DITERPENOID MEMBRANOLIDE COMPOUNDS HAVING ANTI-LEISHMANIA ACTIVITY AND USES THEREOF  
In a screening program, the Antarctic sponge Dendrilla membranosa was found to produce diterpenoid secondary metabolites with activity against the leishmaniasis-causing parasite Leishmania...
9248035 Flared vaginal stent  
A flared vaginal stent having a body portion and an outwardly flared head portion as well as a method of use thereof is presented. The head portion is comprised of an outwardly flared tip,...
US20160022304 SMALL DIAMETER LAPAROSCOPIC TOOL HAVING RELEASABLE TIP  
A laparoscopy tool includes a sheath and a control wire slideably disposed within a lumen of the sheath. The sheath has a diameter of less than 1.6 mm and is introduced through an abdominal...
9241975 Reelin rescues congnitive function  
Disclosed are methods of influencing, and enhancing, cognitive function by increasing, and/or preventing interference with, Reelin levels as well as Reelin signaling. Cognitive function is...
9241851 Hands-free user interface devices  
In one embodiment, a hands-free user interface device includes a first plate, a second plate spaced from the first plate, a sensor associated with the plates adapted to detect when the first plate...
US20160015286 INTEGRATED VECTORCARDIOGRAM SYSTEM AND METHOD OF USE  
An integrated vectorcardiogram (VCG) device having 3 pairs of electrodes placed in three orthogonal directions with the capability to continuously measure the electrical activity of the heart. All...
9238149 Prevention and treatment of alzheimer'S disease through electromagnetic field exposure  
The invention includes a method of treating and preventing a neurological disorder, such as Alzheimer's Disease, in a subject in need thereof by positioning an electromagnetic field emitting...
US20160013410 MASK-STACK-SHIFT METHOD TO FABRICATE ORGANIC SOLAR ARRAY BY SPRAY  
An all-spray fabrication method for large scale inverted organic solar array is provided. Zinc oxide sol gel solutions and revised layers shorten the fabrication process from 2 days to 5 hours and...
9234007 RGD mimetic γ-AApeptides and methods of use  
Embodiments of the present disclosure provide for RGD mimetic γ-AApeptide compounds, γ-AApeptide compounds capable of binding an RGD binding site on integrin αvβ3, linear γ-AApeptide compounds,...
US20160003825 USE OF PKC-ZETA AS A BREAST CANCER TUMORIGENIC BIOMARKER AS WELL AS A TARGET FOR TREATMENT OF BREAST CANCER  
The present invention provides use of protein kinase C-zeta (PKC-ζ) as a diagnostic biomarker for breast cancer tumorigenesis. Also provided are uses of PKC-zeta inhibitors for inhibiting breast...