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Patents and Patent Applications from University of South Florida


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8908796 Orthogonal frequency division multiplexing (OFDM) transmitter and receiver windowing for adjacent channel interference (ACI) suppression and rejection  
An optimum time domain windowing scheme for orthogonal frequency-division multiplexing (OFDM)-based waveforms in the sense of spectral concentration is proposed. Instead of evenly suppressing the...
8908089 Implantable imaging device  
An imaging device for in vivo medical applications that enables minimally invasive surgical procedures. The imaging device includes an elongated frame having a base, a module housing, and an...
8906918 Compositions, methods of use, and methods of treatment  
Embodiments of the present disclosure, in one aspect, relate to a 2,4-diaminoquinazoline compound, pharmaceutical compositions including a 2,4-diaminoquinazoline compound, methods of treatment of a...
8906869 Effective treatment of ovarian cancer using triciribine and related compounds  
The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat ovarian cancer by one or a combination of (i) administering triciribine only to...
8906414 Methods and compositions for improving bioavailability of epigallocatechin gallate (EGCG)  
Compositions and methods of increasing the bioavailability of catechins are presented. Compositions for increasing the bioavailability of catechins include compositions where the catechin is added...
8906052 Method and device for the treatment of hypertrophic cardiomyopathy  
A method and device for the treatment of hypertrophic cardiomyopathy. The device includes a cutting device for resection of a thickened myocardium. The operator positions the cutting device...
US20140356955 FERROMAGNETIC CELL AND TISSUE CULTURE MICROCARRIERS  
A porous, collagen coated, ferromagnetic cell culture microcarrier, which is suitable for in vitro cell and tissue culture and which facilitates 3D multicellular construct generation. Also provided...
8901086 Compositions including triciribine and methods of use thereof  
This invention encompasses combination therapies including TCN, TCN-P, TCN-PM and/or related compounds and one or more additional anti-cancer agents, for example, taxanes a molecule that modulates...
US20140350105 COMPOSITIONS AND METHODS FOR PRODUCING ELEVATED AND SUSTAINED KETOSIS  
Beta-hydroxybutyrate mineral salts in combination with medium chain fatty acids or an ester thereof such as medium chain triglycerides were used to induce ketosis, achieving blood ketone levels of...
US20140350052 Methods and Compositions for Reducing Serum Levels of Immunoglobulin E (IGE)  
The present disclosure provides methods and pharmaceutical compositions for reducing the serum level of immunoglobulin IgE in an animal or human subject. It has been found that reducing or...
8895248 Method for detecting Salmonella species by assaying outer membrane Porin F (ompF)  
The invention relates to a method of detecting the presence of Salmonella in a sample using novel oligonucleotide sequences. Also presented is a kit for putting the method into practice and novel...
US20140343120 METHODS AND COMPOSITIONS FOR REDUCING ACTIVITY OF THE ATRIAL NATRIURETIC PEPTIDE RECEPTOR AND FOR TREATMENT OF DISEASES  
Methods, compositions and devices are provided by the present invention for reducing activity of a natriuretic peptide receptor and other signals. Therapeutic treatments are provided by use of...
8891430 Edge windowing of OFDM based systems  
Various methods and systems are provided for edge windowing of orthogonal frequency division multiplexing (OFDM) systems. In one example, among others, a method includes obtaining an edge windowing...
US20140336945 GENE SIGNATURE FOR THE PREDICTION OF RADIATION THERAPY RESPONSE  
Described are mathematical models and method, e.g., computer-implemented methods, for predicting tumor sensitivity to radiation therapy, which can be used, e.g., for selecting a treatment for a...
US20140336239 COMPOSITIONS AND METHODS FOR MODULATING MYELOID DERIVED SUPPRESSOR CELLS  
Provided are methods and compositions for modulating the differentiation of a myeloid derived suppressor cell (MDSC). In particular, described herein are miR-142 polynucleotides and miR-223...
8883744 Method and composition for modulating canonical Wnt pathway using folate and inositol  
The canonical Wnt signaling pathway is implicated in many disorders including neural tube defects, limb malformations, and heart defects, developmental disorders associated with alcohol exposure...
8881639 Hybrid body armor  
In one embodiment, hybrid body armor includes a ballistic fabric and a plurality of small ballistic plates arranged in a tightly packed array over the ballistic fabric.
US20140330123 IMPLANTABLE SONIC WINDOWS  
A sonic window includes a body sized and configured to close an opening formed through the cranium, wherein at least a part of the body is made of a sonically transparent material through which...
US20140329900 SMALL MOLECULE INHIBITORS OF STAT3 WITH ANTI-TUMOR ACTIVITY  
The present invention concerns compounds, compositions containing these compounds, and methods of using these compounds and compositions as inhibitors of Stat3 signaling, Stat3 dimerization,...
US20140329791 COMPOUNDS AND RELATED METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASES  
Aspects of the invention pertain to chemical compounds, therapeutic compositions, and methods for treating neurodegenerative diseases, in particular, neurodegenerative diseases associated with...
8877752 4(1H)-quinolones having antimalarial activity with reduced chemical resistance  
Provided are 4(1H)-quinolone derivatives effective in inhibiting or eliminating the viability of at least one of the stages in the life-cycle of the malarial parasite, and to show a reduced...
US20140322227 PEPTIDES FOR TREATMENT OF BONE DEFICIENCY AND AUTOIMMUNE DISORDERS  
The present invention concerns the use of HYD1 peptides to reduce activated T-cell numbers and/or to promote bone preservation in vivo. The present invention concerns methods of treating a bone...
8872725 Electronically-tunable flexible low profile microwave antenna  
A low profile antenna that provides high isolation to back-side radiation, is flexible to allow conformal mounting to a surface, and can be tuned over a wide frequency range is conceived. The...
US20140316570 SYSTEMS AND METHODS FOR COMMUNICATING ROBOT INTENTIONS TO HUMAN BEINGS  
In one embodiment, communicating robot intentions to human beings involves determining movements that a robot will make to complete a task, visually communicating a long-term intention of the robot...
8865666 Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof  
This application relates to combination therapies including triciribine and related compounds and bortezomib and derivatives thereof analogs and compositions with reduced toxicity for the treatment...
8864852 Method for the fabrication of electrolyte cavities using surface micromachining  
The present invention is directed to the fabrication of thin aluminum anode batteries using a highly reproducible process that enables high volume manufacturing of the galvanic cells. A method of...
8863737 Sustained modulation of temperature of self heating chemical system  
Exothermic reactions are used in self heating products, such as food, beverages, and clothing. Temperature peaks are important as heat can cause user injuries or increase pressures within the...
US20140309477 CT ATLAS OF THE BRISBANE 2000 SYSTEM OF LIVER ANATOMY FOR RADIATION ONCOLOGISTS  
The method includes the steps of obtaining atlas data in an atlas coordinate set from a computer-readable atlas of hepatic anatomical information including three orders of division and obtaining...
US20140309476 CT ATLAS OF MUSCULOSKELETAL ANATOMY TO GUIDE TREATMENT OF SARCOMA  
The method includes the steps of obtaining atlas data in an atlas coordinate set from a computer-readable atlas of musculoskeletal structure. The atlas contains a data set representing a 3D model...
8858772 Bidirectional electrowetting actuation with voltage polarity dependence  
A novel electrowetting system for the smooth continuous movement of a droplet across a single circuit using a continuous applied voltage regardless of polarity. The actuation of the droplet is...
US20140303111 COMPOSITIONS INCLUDING TRICIRIBINE AND TAXANES AND METHODS OF USE THEREOF  
This application relates to combination therapies including triciribine and related compounds and taxanes and compositions with reduced toxicity thr the treatment and prevention of tumors, cancer,...
US20140303110 EFFECTIVE TREATMENT OF TUMORS AND CANCER WITH TRICIRIBINE AND RELATED COMPOUNDS  
The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat tumors and cancer by one or a combination of (i) administering triciribine only...
US20140302406 Electrode Mesh Galvanic Cells  
The present invention is directed to the fabrication of thin aluminum anode batteries using a highly reproducible process that enables high volume manufacturing of the galvanic cells. A thin...
US20140302011 COMPOSITIONS INCLUDING TRICIRIBINE AND TRASTUZUMAB AND METHODS OF USE THEREOF  
This application relates to combination therapies including triciribine and related compounds and trastuzumab or a salt thereof and compositions with reduced toxicity for the treatment and...
8854621 Systems and methods for determining nanoparticle dimensions  
In one embodiment, the dimensions of nanoparticles are determined by focusing light on a sample of nanoparticles suspended in a solution, collecting light scattered by the nanoparticles, measuring...
8854366 Automated geometric representation of discrete point sets  
A system and method of creating a smooth analytical representation of a geometry using a discrete set of points. A meshfree representation of the geometry is generated. The representation includes...
8853149 Integrin interaction inhibitors for the treatment of cancer  
Integrin interaction inhibitors using a beta-turn promoter are described herein. These peptides are useful in treating cancer, such as multiple myeloma, by administering a therapeutically effective...
US20140296128 MATERIALS AND METHODS FOR TREATMENT OF CANCER AND IDENTIFICATION OF ANTI-CANCER COMPOUNDS  
The subject invention pertains to the treatment of tumors and cancerous tissues and the prevention of tumorigenesis and malignant transformation through the modulation of JAK/STAT3 intracellular...
8846801 Self-healing polycarbonate containing polyurethane nanotube composite  
Thermoplastic elastomers containing carbon nanotubes that is an autonomous, intrinsic, and reversible self healing polymer that requires no intervention to induce self healing, that requires no...
8846653 Delta-tocotrienol treatment and prevention of pancreatic cancer  
Methods are disclosed for treating neoplastic disorders, such as pancreatic cancer, using tocotrienols; namely, gamma-tocotrienol and delta tocotrienol. The antitumorogenic effects of these...
US20140288486 TRANSVAGINAL SPECIMEN EXTRACTION DEVICE  
In laparoscopic surgery, small (5-12 mm diameter) incisions are made in the abdominal wall through which instruments dissect and remove specimens that may be several centimeters in diameter....
8843315 System and method for spatial point-of-interest generation and automated trip segmentation using location data  
This present invention is a spatial data processing system and method that allows the automatic, rapid, scalable analysis and transformation of large amounts of travel behavior data (e.g., tracking...
US20140277139 BONE FUSION SYSTEM  
A method and system for performing bone fusion and/or securing one or more bones, such as adjacent vertebra, are disclosed. The screws include a threaded tip connected to a main shaft and a...
US20140274883 NOVEL ANTIVIRAL COMPOUNDS FROM MARINE EXTRACTS  
The subject invention pertains to novel biologically active extracts from marine algae and to biologically active fractions and components of these extracts. These extracts have been shown to...
US20140258356 COLUMN AND CONSTRAINT GENERATION METHOD FOR OPTIMAL STRATEGIES  
Optimization processes, which are parameter driven for solving interdiction problems, for example, power grid interdiction problems, are provided. An algorithm of the subject invention can include...
US20140255337 METHODS OF TREATING COGNITIVE IMPAIRMENT  
The subject invention concerns materials and methods for treating a person or animal having cognitive impairment. In one embodiment, the method comprises administering an effective amount of one or...
8828451 Akt sensitization of cancer cells  
Most human tumors find ways to resist anticancer drug monotherapy. Akt is considered a likely peptide providing such monotherapy drug resistance. Data indicates that Akt chemoresistance is induced...
US20140248364 DIVALENT-METAL COATED NANOPARTICLES FOR DELIVERY OF COMPOSITIONS INTO THE CENTRAL NERVOUS SYSTEM BY NASAL INSUFFLATION  
The compositions and methods of the disclosure particularly target the divalent metal transporter expressed on olfactory nerve terminals to transport divalent cation-coated or cation-containing...
8822524 Substrate-mimetic Akt inhibitor  
Disclosed herein is a species of peptide and non-peptide inhibitors of Akt, an oncogenic protein. Beginning with a residue of Akt target substrate GSK-3, the functional domains of the GSK-3 residue...
US20140242193 LITHIUM COMPOSITIONS  
2:1 cocrystals of amino acids and Li+ salts crystallize from hot water to afford water stable cationic networks based upon tetrahedral lithium cations: bilayered square grids, a lithium zeolitic...