Patents and Patent Applications from University of South Florida


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9372490 System and method for distributed voltage regulator-gating  
A system and method for adaptive activity management of on-chip voltage regulators based upon the workload information is provided to force each on-chip regulator to operate in its most...
9364647 Shunt catheter system  
A shunt catheter system and method of use thereof. The system generally includes an open-ended ventricular catheter with drainage apertures and safety flap valves, a reservoir with inline filter,...
9364456 Ketone esters for treatment of angelman syndrome  
The invention concerns a method of treating Angelman Syndrome (AS) in a subject, comprising inducing ketosis in the subject by administering a therapeutically effective amount of a ketone ester,...
US20160160274 MATERIALS AND METHODS FOR PROFILING MICRORNAS  
The present invention provides materials and methods for detecting, quantifying, and/or high-throughput-profiling microRNAs. Advantageously, the present invention is more sensitive and specific...
US20160159981 Peptide-Based Materials  
The subject invention pertains to peptide-based materials comprising cross-linked peptides with random amino acid sequences that are soluble in water or ethanol before crosslinking but insoluble...
US20160158364 Menthol-based Nanoparticles for Drug Delivery  
The subject invention pertains to formulations comprising poly(menthyl acrylate) nanoparticles comprising at least one active ingredient contained in a plurality of hydrophobic carriers and...
9363127 Orthogonal frequency division multiplexing (OFDM) transmitter and receiver windowing for adjacent channel interference (ACI) suppression and rejection  
An optimum time domain windowing scheme for orthogonal frequency-division multiplexing (OFDM)-based waveforms in the sense of spectral concentration is proposed. Instead of evenly suppressing the...
9360299 Incoherent digital holographic adaptive optics  
In one embodiment, generating an aberration-compensated image of an object field includes generating a full-field complex hologram of the object field, generating a guide star complex hologram of...
9359347 Inhibitors of Akt/PKB with anti-tumor activity  
The subject invention concerns materials and methods for inhibiting the Akt/PKB pathway. In one embodiment, a compound of the invention inhibits kinase activity and/or phosphorylation levels of...
US20160151493 Heating Elements Having Plasmonic Nanoparticles for Localized Heating  
In one embodiment, a heating element includes a central particle and a plurality of plasmonic nanoparticles attached to the central particle, wherein the nanoparticles undergo plasmonic heating...
US20160151460 Method of treating skeletal dysplasias using vessel dilator  
C-natriuretic peptide (CNP) has been shown to regulate proliferation of mouse and rat osteoblasts. Genetic deletion of CNP results in dwarfism. CNP effects on bone growth involve inhibition of MEK...
US20160151311 N,N'-DI-1 NAPHTHYLGUANIDINE HCL (NAGH) AND N,N'-DI-P-NITROPHENYLGUANIDINE HCL (NAD) TREATMENT FOR STROKE AT DELAYED TIMEPOINTS  
A method of treating stroke by administration of a novel sigma agonist is presented. Twenty-four hours after MCAO, systemic administration of several novel sigma agonists including: Bromo-DTG;...
9353417 Method of diagnosing large granular lymphocyte leukemia using alternative splice variants of serine proteases  
Methods of diagnosing large granular lymphocytic leukemia are provided herein. Novel splice variants of Granzyme B and Granzyme H as well as methods for screening for compositions regulating the...
9351981 Use of PKC-iota inhibitors for the treatment of breast cancer  
The subject invention pertains to uses of PKC-iota inhibitors for treatment of breast cancer. In one embodiment, the subject invention provides novel uses of 1H-imidazole-4-carboxamide,...
9345682 Inhibition of STAT3 signal transduction for human cancer therapy  
Signal Transducer and Activator of Transcription (STAT) proteins have a fundamental role cell signaling, and are activated by a large number of cytokines and growth factors. One member of the STAT...
9345249 Method of supplementing cytokine, chemokine and growth factors in donor human milk  
Donor milk has become a standard of care for feeding preterm infants, particularly those with gestational ages of 34 weeks or less, whose mothers are not lactating or not producing sufficient milk...
US20160139561 FULL-COLOR INCOHERENT DIGITAL HOLOGRAPHY  
In one embodiment, a color holographic image is created by generating a separate complex hologram for each of multiple different colors of an object field illuminated with incoherent light,...
US20160136273 COMPOSITIONS INCLUDING TRICIRIBINE AND TRASTUZUMAB AND METHODS OF USE THEREOF  
This application relates to combination therapies including triciribine and related compounds and trastuzumab or a salt thereof and compositions with reduced toxicity for the treatment and...
US20160136228 COMPOSITIONS INCLUDING TRICIRIBINE AND BORTEZOMIB AND DERIVATIVES THEREOF AND METHODS OF USE THEREOF  
This application relates to combination therapies including triciribine and related compounds and bortezomib and derivatives thereof analogs and compositions with reduced toxicity for the...
9339574 Compositions and methods for reducing or preventing medical device-related infections  
Provided herein is a method of reducing a microbial infection of a heparinized surface wherein heparin precipitation is reduced as compared to a control. In some embodiments a composition...
9328035 Systems and methods for producing liquid hydrocarbon fuels  
In one embodiment, liquid hydrocarbon fuels are produced in a single reactor using a hybrid catalyst system including a reforming catalyst, a Fischer-Tropsch synthesis (FTS) catalyst, and a porous...
US20160116482 Target Binding Molecules Identified by Kinetic Target-Guided Synthesis  
Methods of identifying target binding molecules by target guided synthesis are provided. The methods include providing two or more fragments capable of reacting to form the target binding molecule...
9325047 Dynamically reconfigurable bandpass filters  
In one embodiment, a dynamically reconfigurable bandpass filter includes a resonator loop and a microfluidic channel proximate to the resonator loop, the channel containing a conductor, wherein...
9324565 Systems and methods for forming contact definitions  
In one embodiment, a method for fabricating thin film tunnel devices includes forming multiple bottom electrodes on a substrate, depositing an insulating layer of material on top of each bottom...
9322508 Systems and methods for applying reinforcement material to existing structures  
In one embodiment, a system for applying reinforcement material to an existing structure includes a work rail adapted to be temporarily secured to a bottom surface of the structure, adhesive...
9321176 Systems and methods for planning a robot grasp based upon a demonstrated grasp  
In one embodiment, planning a robot grasp of an object includes determining a grasp type that would be used by a human being to grasp the object, determining a position and orientation of the...
US20160109776 Metal Sensitized Color Changing Material  
The subject invention pertains to color changeable, film materials comprising a metal substrate layer; a conducting polymer or conducting polymer composite layer; and an electrolyte layer. The...
US20160108108 INFLAMMATORY DISEASE DIAGNOSIS AND METHODS OF TREATMENT USING LIPOPOLYSACCHARIDES-RESPONSIVE BEIGE-LIKE ANCHOR  
Anti-cytokine therapy has revolutionized immunological disease treatment, but is not always effective and subject to treatment resistance as the cytokine cascade is highly redundant and multiple...
US20160106997 PREVENTION AND TREATMENT OF BRAIN DISEASES AND DISORDERS RELATED TO ABNORMAL PROTEIN AGGREGATION THROUGH ELECTROMAGNETIC FIELD TREATMENT  
A method of treating and preventing a neurological disorder, such as Alzheimer's disease, in a subject in need thereof by positioning an electromagnetic field emitting source proximal to the...
US20160106767 USE OF PKC-IOTA INHIBITORS FOR THE TREATMENT OF BREAST CANCER  
The subject invention pertains to uses of PKC-iota inhibitors for treatment of breast cancer. In one embodiment, the subject invention provides novel uses of 1H-imidazole-4-carboxamide,...
9319253 Edge windowing of OFDM based systems  
Various methods and systems are provided for edge windowing of orthogonal frequency division multiplexing (OFDM) systems. In one example, among others, a method includes obtaining an edge...
9318632 Bare quantum dots superlattice photonic devices  
Manipulation of the passivation ligands of colloidal quantum dots and use in QD electronics. A multi-step electrostatic process is described which creates bare QDs, followed by the formation of QD...
9314375 Method for auto-regulation of intraocular pressure  
A method for controlling intraocular eye pressure via fluid exchange in the body is presented. The method may comprise providing a system to sense and regulate pressure, then implanting the system...
9314103 Sling-back chair  
The Sling-Back Chair is a new hammock hybrid chair. The chair is a cross between a lounge style chair and a hammock. The chair can be optioned for interior or exterior, with personalization...
9308210 Method for modulating canonical Wnt pathway using folate and inositol  
The canonical Wnt signaling pathway is implicated in wound healing. Administration of a composition having myo-inositol and folic acid upregulates fibronectin and provides the greatest protection...
US20160100414 SUPERPOSED SIGNALING FOR BANDWIDTH EFFICIENCY  
Systems, methods and instrumentalities are disclosed for superposed signaling for bandwidth efficiency in wireless communications. Homogeneous and heterogeneous signals may be superposed on the...
9301965 Method of treating ovarian cancer using a PKC inhibitor  
A method of treating ovarian cancer by administering a PKC inhibitor is presented herein. It was found that administering a PKC inhibitor, such as ACPD or ICA-1, to ovarian cancer cells inhibited...
US20160089344 NANOPARTICLE TARGETED DRUG DELIVERY TO THE LUNGS USING EXTRA-TESTICULAR SERTOLI CELLS  
A method of delivering a compound of interest to the lungs of a subject by the intravenous injection of Sertoli cells loaded with a plurality of chitosan nanoparticles coupled with the compound of...
9297995 Automatic stereological analysis of biological tissue including section thickness determination  
Systems and methods are provided for automatic determination of slice thickness of an image stack in a computerized stereology system, as well as automatic quantification of biological objects of...
9297816 Devices and methods for measuring blood coagulation  
In one embodiment, a device for measuring blood coagulation includes a substrate having a surface, an optical waveguide provided on the surface of the substrate, the waveguide having a tip, and...
9295302 Gait-altering shoes  
In one embodiment, a gait-altering shoe includes a frame adapted to support a user's foot and at least one wheel that supports the frame above a walking surface, the wheel having a radius that...
9291507 Differential capacitive readout system and method for infrared imaging  
An IR imaging system comprising microelectromechanical systems (MEMS) differential capacitive infrared sensors within a sensor array formed on a monolithic integrated circuit substrate, or flip...
9289421 Methods and compositions for reducing serum levels of immunoglobulin E (IgE)  
The present disclosure provides methods and pharmaceutical compositions for reducing the serum level of immunoglobulin IgE in an animal or human subject. It has been found that reducing or...
9286687 System and method for estimating the magnetization states of a nanomagnet array  
A system and method for image-processing that will facilitate automatically analyzing and estimating atomic force microscopy (AFM) images and magnetic force microscopy (MFM) images of fabricated...
US20160068503 (-)-EPIGALLOCATECHIN GALLATE DERIVATIVES FOR INHIBITING PROTEASOME  
A method of reducing tumor cell growth, the method including administering an effective amount of a compound having the formula:
US20160067207 COMPOSITIONS AND METHODS FOR PRODUCING ELEVATED AND SUSTAINED KETOSIS  
Beta-hydroxybutyrate mineral salts in combination with medium chain fatty acids or an ester thereof such as medium chain triglycerides were used to induce ketosis, achieving blood ketone levels of...
9277912 Systems and methods for ankle syndesmosis fixation  
In one embodiment, a fixation system includes an anchor adapted to be implanted within a first bone, a washer adapted to be associated with a second bone that is to be secured to the first bone,...
9276556 Micromechanical devices based on piezoelectric resonators  
In some embodiments, a micromechanical filter includes multiple subfilters, each subfilter comprising multiple piezoelectric resonators mechanically coupled in series, wherein the subfilters are...
9273762 Four-linkage backpack relocator  
A device to help an individual with a disability carry his or her bag or storage unit on their wheelchair or other mobility device, without requiring a large space to deploy the storage and...
US20160053319 MICRO-RNAS MODULATING IMMUNITY AND INFLAMMATION  
MicroRNAs are shown to be up- and/or down-regulated in inflammation and immune cells using a mouse model of asthma and regulatory T cells as source of RNA, respectively. Modulating the expression...