Patents and Patent Applications from University of South Florida


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9442116 Method of predicting chemotherapeutic responsiveness of cancer  
Disclosed is a method of predicting clinical tumor outcome by providing gene expression from a tumor sample. The method utilizes a novel genetic screen to identify genes that contribute to...
9439978 Multilayered magnetic micelle compositions and methods for their use  
Provided herein are compositions comprising a micelle having a hydrophobic superparmagnetic iron oxide nanoparticle (SPION) core, a first coating comprising a cationic polymer, and a second...
US20160260211 SYSTEMS AND METHODS FOR DIAGNOSING TUMORS IN A SUBJECT BY PERFORMING A QUANTITATIVE ANALYSIS OF TEXTURE-BASED FEATURES OF A TUMOR OBJECT IN A RADIOLOGICAL IMAGE  
An example method for diagnosing tumors in a subject by performing a quantitative analysis of a radiological image can include identifying a region of interest (ROI) in the radiological image,...
US20160258960 DETECTION OF CANCER BY ELEVATED LEVELS OF BCL-2  
The present invention relates to a method for the diagnosis, prognosis, and monitoring of cancer, such as early or late stage ovarian cancer, in a subject by detecting Bcl-2 in a biological sample...
US20160257712 INTEGRIN INTERACTION INHIBITORS FOR THE TREATMENT OF CANCER  
Integrin interaction inhibitors using a beta-turn promoter are described herein. These peptides are useful in treating cancer, such as multiple myeloma, by administering a therapeutically...
9437906 Electrode mesh galvanic cells  
The present invention is directed to the fabrication of thin aluminum anode batteries using a highly reproducible process that enables high volume manufacturing of the galvanic cells. A thin...
9434926 Graphene hydrogel and methods of using the same  
Provided herein are hydrogel compositions containing graphene, chitosan, a polyethylene (glycol) diacrylate (PEGDA). The hydrogel can optionally contain an N-isopropylacrylamide (NIPAM) (TPCG...
9433682 Graphene hydrogel and method for using the same  
Provided herein is a hydrogel composition comprising a graphene, a chitosan, and a polyethylene (glycol) diacrylate (PEGDA) (PCG hydrogel). In some embodiments, the hydrogel further comprises a...
9433635 Effective treatment of ovarian cancer using triciribine and related compounds  
The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat ovarian cancer by one or a combination of (i) administering triciribine only...
9433581 Poly(vinyl benzoate) nanoparticles for molecular delivery  
The present invention comprises poly(vinyl benzoate) nanoparticle suspensions as molecular carriers. These nanoparticles can be formed by nanoprecipitation of poly(vinyl benzoate) in water using...
9428849 Polypeptide electrospun nanofibrils of defined composition  
Electrospun nanofibrils and methods of preparing the same are provided. The electrospun nanofibrils comprise at least one polypeptide. A polypeptide can be dissolved in a solution, and the...
9426010 Adaptive symbol transition method for OFDM-based cognitive radio systems  
Modulated orthogonal frequency division multiplexing (OFDM) subcarriers generate high sidelobes, resulting in adjacent channel interference (ACI). Current sidelobe suppression techniques, such as...
9425397 Method of manufacturing inverted organic solar microarray for applications in microelectromechanical systems  
The fabrication and characterization of large scale inverted organic solar array fabricated using all-spray process is disclosed. Solar illumination has been demonstrated to improve transparent...
9417610 Incoherent digital holographic adaptive optics  
An aberration-compensated image of an object field is created by generating a full-field complex hologram of the object field, generating a guide star complex hologram of a guide star selected...
9416456 Nano-hybrid structured regioregular polyhexylthiophene (RRPHTh) blend films for production of photoelectrochemical energy  
The novel photoelectrochemical nano-hybrid film fabricated by blending regioregular polyhexylthiophene (RRPHTh) with titanium oxide (TiO2), Zinc oxide (ZnO) and nanodiamond (ND) nanoparticles on...
9415298 Modern dice  
The present invention includes a novel and modern numbering system design modernizing the design of gaming pieces, such as dice and dominos, while maintaining the qualities of utility for which...
9414904 Sacrocolpopexy/sacrocervicopexy vaginal positioning and mesh retention system  
A vaginal support device, vaginal positioning system and associated method of treating pelvic prolapse is presented herein. Vaginal support device contains flat superior and inferior surfaces to...
US20160229892 CYCLIC PEPTIDE CONJUGATES AND METHODS OF USE  
The present invention concerns cyclic compounds, compositions comprising the cyclic compounds, linkers, a method of preparing a carrying agent:cyclic compound adduct, a method for treating...
9410956 Micro-RNA profiling in ovarian cancer  
MicroRNAs (miRNAs) represent a novel class of genes that function as negative regulators of gene expression and have recently been implicated in several cancers. However, aberrant miRNA expression...
9410212 Kit for detecting Salmonella species by assaying outer membrane porin F (ompF)  
The invention relates to a method of detecting the presence of Salmonella in a sample using novel oligonucleotide sequences. Also presented is a kit for putting the method into practice and novel...
9409927 Super lewis acidic borate esters as 18F-labeled PET probes  
Compounds having a 1-bora-1-fluoro-2,6,7-trioxabicyclo[2.2.2]octane moiety wherein the fluorine is 18F are described. Also described are reagents for radiolabeling a molecule having Formula I....
9404105 Polyhedral cage-containing mesoporous metal-organic frameworks as platform for biocatalysis, methods of making these frameworks, and methods of using these frameworks  
Embodiments of the present disclosure provide compositions including polyhedral mesoporous metal-organic framework including a biomolecule (e.g., enzyme), methods of making these compositions,...
9402870 HUCBC treatment of amyloid associated disease  
Administration of human umbilical cord blood cells (HUCBC) or HUCBC-derived plasma is used to treat amyloid-based diseases, such as Alzheimer's disease, Huntington's disease, cerebral amyloid...
9402530 Minimally invasive networked surgical system and method  
A system for performing non-invasive networked medical procedures including a number of in vivo medical devices, a communication path between at least two of the devices, an ex vivo control unit...
9401437 Partially-sprayed layer organic solar photovoltaic cell using a self-assembled monolayer and method of manufacture  
The fabrication and characterization of large scale inverted organic solar array fabricated using all-spray process is disclosed. Solar illumination has been demonstrated to improve transparent...
9399631 Polyphenol proteasome inhibitors, synthesis, and methods of use  
The present invention relates to synthetic green tea derived polyphenolic compounds, their modes of syntheses, and their use in inhibiting proteasomal activity and in treating cancers. The present...
9399039 Inhibitors of the FKBP51 protein from a high-throughput drug screen and methods of use  
The subject invention concerns materials and methods for treating depression, stress disorders, such as PTSD, anxiety disorders, and/or a neurodegenerative disease or condition in a person or...
US20160209422 METHODS OF SYNTHESIZING y-AAPEPTIDES, y-AAPEPTIDE BUILDING BLOCKS, y-AAPEPTIDE LIBRARIES, AND y-AAPEPTIDE INHIBITORS OF Ab40 AGGREGATES  
Embodiments of the present disclosure provide for γ-AApeptides, γ-AApeptide building blocks, methods of making γ-AApeptides and libraries of γ-AApeptides, methods of screening the γ-AApeptide...
US20160206644 Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof  
This application relates to combination therapies including triciribine compounds and epidermal growth factor receptor inhibitor compounds, particularly erlotinib-like compounds and compositions...
9394270 Cytotoxin compounds and methods of isolation  
The present invention concerns groups of compounds derived from tunicates of the Synoicum species, as well as to pharmaceutical compositions comprising these compounds, and uses thereof. Extracts...
9389685 Vision based brain-computer interface systems for performing activities of daily living  
In one embodiment, assisting a user in performing an action in relation to an object of interest includes capturing an image of an environment, identifying boundaries of objects within the image,...
US20160197213 BARE QUANTUM DOTS SUPERLATTICE PHOTONIC DEVICES  
Manipulation of the passivation ligands of colloidal quantum dots and use in QD electronics. A multi-step electrostatic process is described which creates bare QDs, followed by the formation of QD...
9384877 Magneto dielectric polymer nanocomposites and method of making  
In accordance with the present invention, novel superparamagnetic magneto-dielectric polymer nanocomposites are synthesized using a novel process. The tunability of the dielectric/magnetic...
9384416 Quantitative image analysis applied to the grading of vitreous haze  
The present invention includes an automated method for grading the blurring of ocular fundus images to permit automated grading of severity of vitritis. Standard fundoscopic images are converted...
9381029 Incision-less laparoscopic instrument  
A laparoscopic instrument is placed into the abdomen without the creation of a skin incision. The laparoscopic instrument includes a shaft that does not exceed 1.6 mm in diameter. The shaft has a...
9380058 Systems and methods for anonymous authentication using multiple devices  
A system and method of anonymous authentication is described. In operation, the authenticator receives a request to access a resource from one of the user devices of an associated set of user...
9377758 Incoherent digital holographic adaptive optics  
In one embodiment, generating an aberration-compensated image of an object field includes generating a full-field complex hologram of the object field, generating a guide star complex hologram of...
9376937 Method and system for generating power from low- and mid- temperature heat sources using supercritical rankine cycles with zeotropic mixtures  
A method and system for generating power from low- and mid-temperature heat sources using a zeotropic mixture as a working fluid. The zeotropic mixture working fluid is compressed to pressures...
9375400 Manganese ion coated nanoparticles for delivery of compositions into the central nervous system by nasal insufflation  
The compositions and methods of the disclosure particularly target the divalent metal transporter expressed on olfactory nerve terminals to transport divalent cation-coated or cation-containing...
9375228 Laparoscopic tool for grasping tissue  
A laparoscopic tool includes a base having a bore that receives the proximal end of an elongate outer tube having a lumen in axial alignment with the bore. An elongate inner rod is slideably...
US20160182500 SYSTEMS AND METHODS FOR ANONYMOUS AUTHENTICATION USING MULTIPLE DEVICES  
A system and method of anonymous authentication is described. In operation, the authenticator receives a request to access a resource from one of the user devices of an associated set of user...
US20160180072 SYSTEM AND METHODS FOR AUTHENTICATION USING MULTIPLE DEVICES  
A system and method of authentication using an authenticator computing device and at least two registered user devices is described. In operation, the authenticator computing device receives a...
US20160175274 TREATING AN ATYPICAL PROTEIN KINASE C ENZYME ABNORMALITY  
Provided herein are compounds, compositions, pharmaceutical formulations, methods of treating and methods of using aPKC inhibitors for treating and/or preventing of aPKC abnormalities.
9372490 System and method for distributed voltage regulator-gating  
A system and method for adaptive activity management of on-chip voltage regulators based upon the workload information is provided to force each on-chip regulator to operate in its most...
9364647 Shunt catheter system  
A shunt catheter system and method of use thereof. The system generally includes an open-ended ventricular catheter with drainage apertures and safety flap valves, a reservoir with inline filter,...
9364456 Ketone esters for treatment of angelman syndrome  
The invention concerns a method of treating Angelman Syndrome (AS) in a subject, comprising inducing ketosis in the subject by administering a therapeutically effective amount of a ketone ester,...
US20160160274 MATERIALS AND METHODS FOR PROFILING MICRORNAS  
The present invention provides materials and methods for detecting, quantifying, and/or high-throughput-profiling microRNAs. Advantageously, the present invention is more sensitive and specific...
US20160159981 Peptide-Based Materials  
The subject invention pertains to peptide-based materials comprising cross-linked peptides with random amino acid sequences that are soluble in water or ethanol before crosslinking but insoluble...
US20160158364 Menthol-based Nanoparticles for Drug Delivery  
The subject invention pertains to formulations comprising poly(menthyl acrylate) nanoparticles comprising at least one active ingredient contained in a plurality of hydrophobic carriers and...
9363127 Orthogonal frequency division multiplexing (OFDM) transmitter and receiver windowing for adjacent channel interference (ACI) suppression and rejection  
An optimum time domain windowing scheme for orthogonal frequency-division multiplexing (OFDM)-based waveforms in the sense of spectral concentration is proposed. Instead of evenly suppressing the...