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Patents and Patent Applications from University of South Florida


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8872725 Electronically-tunable flexible low profile microwave antenna  
A low profile antenna that provides high isolation to back-side radiation, is flexible to allow conformal mounting to a surface, and can be tuned over a wide frequency range is conceived. The...
US20140316570 SYSTEMS AND METHODS FOR COMMUNICATING ROBOT INTENTIONS TO HUMAN BEINGS  
In one embodiment, communicating robot intentions to human beings involves determining movements that a robot will make to complete a task, visually communicating a long-term intention of the robot...
8865666 Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof  
This application relates to combination therapies including triciribine and related compounds and bortezomib and derivatives thereof analogs and compositions with reduced toxicity for the treatment...
8864852 Method for the fabrication of electrolyte cavities using surface micromachining  
The present invention is directed to the fabrication of thin aluminum anode batteries using a highly reproducible process that enables high volume manufacturing of the galvanic cells. A method of...
8863737 Sustained modulation of temperature of self heating chemical system  
Exothermic reactions are used in self heating products, such as food, beverages, and clothing. Temperature peaks are important as heat can cause user injuries or increase pressures within the...
US20140309477 CT ATLAS OF THE BRISBANE 2000 SYSTEM OF LIVER ANATOMY FOR RADIATION ONCOLOGISTS  
The method includes the steps of obtaining atlas data in an atlas coordinate set from a computer-readable atlas of hepatic anatomical information including three orders of division and obtaining...
US20140309476 CT ATLAS OF MUSCULOSKELETAL ANATOMY TO GUIDE TREATMENT OF SARCOMA  
The method includes the steps of obtaining atlas data in an atlas coordinate set from a computer-readable atlas of musculoskeletal structure. The atlas contains a data set representing a 3D model...
8858772 Bidirectional electrowetting actuation with voltage polarity dependence  
A novel electrowetting system for the smooth continuous movement of a droplet across a single circuit using a continuous applied voltage regardless of polarity. The actuation of the droplet is...
US20140303111 COMPOSITIONS INCLUDING TRICIRIBINE AND TAXANES AND METHODS OF USE THEREOF  
This application relates to combination therapies including triciribine and related compounds and taxanes and compositions with reduced toxicity thr the treatment and prevention of tumors, cancer,...
US20140303110 EFFECTIVE TREATMENT OF TUMORS AND CANCER WITH TRICIRIBINE AND RELATED COMPOUNDS  
The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat tumors and cancer by one or a combination of (i) administering triciribine only...
US20140302406 Electrode Mesh Galvanic Cells  
The present invention is directed to the fabrication of thin aluminum anode batteries using a highly reproducible process that enables high volume manufacturing of the galvanic cells. A thin...
US20140302011 COMPOSITIONS INCLUDING TRICIRIBINE AND TRASTUZUMAB AND METHODS OF USE THEREOF  
This application relates to combination therapies including triciribine and related compounds and trastuzumab or a salt thereof and compositions with reduced toxicity for the treatment and...
8854621 Systems and methods for determining nanoparticle dimensions  
In one embodiment, the dimensions of nanoparticles are determined by focusing light on a sample of nanoparticles suspended in a solution, collecting light scattered by the nanoparticles, measuring...
8854366 Automated geometric representation of discrete point sets  
A system and method of creating a smooth analytical representation of a geometry using a discrete set of points. A meshfree representation of the geometry is generated. The representation includes...
8853149 Integrin interaction inhibitors for the treatment of cancer  
Integrin interaction inhibitors using a beta-turn promoter are described herein. These peptides are useful in treating cancer, such as multiple myeloma, by administering a therapeutically effective...
US20140296128 MATERIALS AND METHODS FOR TREATMENT OF CANCER AND IDENTIFICATION OF ANTI-CANCER COMPOUNDS  
The subject invention pertains to the treatment of tumors and cancerous tissues and the prevention of tumorigenesis and malignant transformation through the modulation of JAK/STAT3 intracellular...
8846801 Self-healing polycarbonate containing polyurethane nanotube composite  
Thermoplastic elastomers containing carbon nanotubes that is an autonomous, intrinsic, and reversible self healing polymer that requires no intervention to induce self healing, that requires no...
8846653 Delta-tocotrienol treatment and prevention of pancreatic cancer  
Methods are disclosed for treating neoplastic disorders, such as pancreatic cancer, using tocotrienols; namely, gamma-tocotrienol and delta tocotrienol. The antitumorogenic effects of these...
US20140288486 TRANSVAGINAL SPECIMEN EXTRACTION DEVICE  
In laparoscopic surgery, small (5-12 mm diameter) incisions are made in the abdominal wall through which instruments dissect and remove specimens that may be several centimeters in diameter....
8843315 System and method for spatial point-of-interest generation and automated trip segmentation using location data  
This present invention is a spatial data processing system and method that allows the automatic, rapid, scalable analysis and transformation of large amounts of travel behavior data (e.g., tracking...
US20140277139 BONE FUSION SYSTEM  
A method and system for performing bone fusion and/or securing one or more bones, such as adjacent vertebra, are disclosed. The screws include a threaded tip connected to a main shaft and a...
US20140274883 NOVEL ANTIVIRAL COMPOUNDS FROM MARINE EXTRACTS  
The subject invention pertains to novel biologically active extracts from marine algae and to biologically active fractions and components of these extracts. These extracts have been shown to...
US20140258356 COLUMN AND CONSTRAINT GENERATION METHOD FOR OPTIMAL STRATEGIES  
Optimization processes, which are parameter driven for solving interdiction problems, for example, power grid interdiction problems, are provided. An algorithm of the subject invention can include...
US20140255337 METHODS OF TREATING COGNITIVE IMPAIRMENT  
The subject invention concerns materials and methods for treating a person or animal having cognitive impairment. In one embodiment, the method comprises administering an effective amount of one or...
8828451 Akt sensitization of cancer cells  
Most human tumors find ways to resist anticancer drug monotherapy. Akt is considered a likely peptide providing such monotherapy drug resistance. Data indicates that Akt chemoresistance is induced...
US20140248364 DIVALENT-METAL COATED NANOPARTICLES FOR DELIVERY OF COMPOSITIONS INTO THE CENTRAL NERVOUS SYSTEM BY NASAL INSUFFLATION  
The compositions and methods of the disclosure particularly target the divalent metal transporter expressed on olfactory nerve terminals to transport divalent cation-coated or cation-containing...
8822524 Substrate-mimetic Akt inhibitor  
Disclosed herein is a species of peptide and non-peptide inhibitors of Akt, an oncogenic protein. Beginning with a residue of Akt target substrate GSK-3, the functional domains of the GSK-3 residue...
US20140242193 LITHIUM COMPOSITIONS  
2:1 cocrystals of amino acids and Li+ salts crystallize from hot water to afford water stable cationic networks based upon tetrahedral lithium cations: bilayered square grids, a lithium zeolitic...
8816784 Silicon-based atomic clocks  
In one embodiment, a silicon-based atomic clock for use in an electronic device includes a single-isotope silicon crystal and energy level transitions within the silicon are used as a frequency...
8815502 Post protein hydrolysis removal of a potent ribonuclease inhibitor and the enzymatic capture of DNA  
The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate...
8815260 Treatment of restenosis and stenosis with dasatinib  
A method for treating or inhibiting artery obstructive disease, such as restenosis after angioplasty and stenting procedures and stenosis after coronary artery bypass surgery, in a subject by...
8815144 Carbon nanotube/polymer composites resistant to ionizing radiation  
Polymer composites directed to single wall carbon nanotubes (SWNT) dispersed within poly(methyl methacrylate) (PMMA) and their methods of synthesis. Composites of the present invention are also...
US20140235659 DELTA-TOCOTRIENOL TREATMENT AND PREVENTION OF PANCREATIC CANCER  
Methods are disclosed for treating neoplastic disorders, such as pancreatic cancer, using tocotrienols; namely, gamma-tocotrienol and delta tocotrienol. The antitumorogenic effects of these...
US20140235565 N-ALKYLTHIO BETA-LACTAMS, ALKYL-COENZYME A ASYMMETRIC DISULFIDES, AND ARYL-ALKYL DISULFIDES AS ANTI-BACTERIAL AGENTS  
The present invention provides N-alkylthio β-lactams and disulfide compounds (e.g., alkyl-coenzyme A asymmetric disulfides or aryl-alkyl disulfides), compositions containing such compounds, and ...
US20140234401 METHOD OF TREATING INFLAMMATION USING HUMAN IMMUNOSUPPRESSIVE PROTEIN  
A method of treating inflammation by administering a therapeutically effective amount of a human immunosuppressant protein (HISP) to a subject is presented. The inventors have discovered a novel...
8808301 Rapid custom intra-articular ligament reconstruction guide  
Custom surgical guides based on the patient's unique anatomy that can be quickly and accurately applied intra-operatively without navigation are disclosed. The device is created using preoperative...
8803533 Noncontact determination of interface trap density for semiconductor-dielectric interface structures  
Embodiments of the subject method and apparatus relate to a sequence of noncontact Corona-Kelvin Metrology that allows the determination and monitoring of interface properties in dielectric/wide...
8802647 Materials and methods for prevention and treatment of RNA viral diseases  
The subject invention concerns a method of inhibiting an RNA virus infection within a patient by increasing the amount of 2-5 oligoadenylate synthetase (2-5 AS) activity within the patient....
8802643 Method for the treatment of malignancies  
A method of treating cancerous tumors is presented herein. The method includes injecting an effective dose of a plasmid encoded for IL-12, B7-1 or IL-15 into a cancerous tumor and subsequently...
8802638 Flavonoid treatment of glycogen synthase kinase-based disease  
The flavonoid luteolin reduces amyloid-β peptide (Aβ) generation. Luteolin is also a selective GSK-3 inhibitor that 1) decreases amyloidogenic γ-secretase APP processing, and 2) promotes pr...
US20140221658 INHIBITION OF CELL PROLIFERATION  
The disclosed modulators of Rb:Raf-1 interactions are potent, selective disruptors of Rb:Raf-1 binding, with IC50 values ranging from 80 nM to 500 nM. Further, these compounds are surprisingly...
US20140221473 Compositions, Methods of Use, and Methods of Treatment  
Embodiments of the present disclosure provide compositions including ketamine analogues, salts, and disalts, pharmaceutical compositions including ketamine analogues, salts, or disalts, methods of...
8796235 Methods for attenuating dengue virus infection  
The present invention pertains to vectors for regulating gene expression having at least one gene expressing cassette and at least one gene suppressing cassette, wherein the gene expression...
8795498 Microbial cell and particle selection system and method of use  
The invention comprises two key components: dielectrophoresis (DEP) and reversible binding surfaces. DEP has become an important tool for trapping dielectric particles. Moreover, DEP can manipulate...
8793849 Method of manufacturing high frequency thickness shear mode gas and organic vapor sensors  
A method of fabricating a thickness shear mode (TSM) gas and organic vapor sensor having a visco-elastic polymer coating and a fundamental frequency greater than 20 MHz. The method begins by...
US20140213802 (-)-Epigallocatechin Gallate Derivatives for Inhibiting Proteasome  
A method of reducing tumor cell growth, the method including administering an effective amount of a compound having the formula:
US20140213604 PROTEIN KINASE C AS A TARGET FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS  
The subject invention concerns a method of inhibiting respiratory syncytial virus (RSV) infection in a patient by decreasing the endogenous protein kinase C (PKC) activity within the patient....
US20140209564 Method for the Fabrication of Electrolyte Cavities Using Surface Micromachining  
The present invention is directed to the fabrication of thin aluminum anode batteries using a highly reproducible process that enables high volume manufacturing of the galvanic cells. A method of...
US20140205570 RECOMBINANT ADENO-ASSOCIATED VIRUS-MEDIATED EXPRESSION OF FRACTALKINE FOR TREATMENT OF NEUROINFLAMMATORY AND NEURODEGENERATIVE DISEASES  
The subject invention pertains to the use of fractalkine (FKN, CX3CL1) and its receptor CX3CR1 for treatment of neuroinflammation and/or neurodegeneration. In one embodiment, the present invention...
8788015 Method of rapidly visualizing essential neural pathways  
A method of optimizing pre-operative procedures in the field of neurosurgery. The method facilitates the identification of essential fiber tract pathways that must be avoided when planning and...