Patents and Patent Applications from University of South Florida


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US20160338962 POLY(VINYL BENZOATE) NANOPARTICLES FOR MOLECULAR DELIVERY  
The present invention comprises poly(vinyl benzoate) nanoparticle suspensions as molecular carriers. These nanoparticles can be formed by nanoprecipitation of poly(vinyl benzoate) in water using...
US20160338682 PNEUMATIC SYSTEM AND METHOD FOR INTERMITTENTLY RIGIDIFYING AN ENDOSCOPIC SPECIMEN RETAINING CARRIER  
An insufflation/desufflation apparatus/system, and method of use thereof. An airtight tube is secured circumferentially to the opening of an endoscopic containment bag. The tube is attached to a...
9501946 Systems and methods for stable haptic feedback over packet-switched networks  
Providing haptic feedback to a user over a packet-switched network includes sensing movement of a haptic device by a user, the haptic device being configured to control a first virtual object...
9499587 Gamma-AApeptides with potent and broad-spectrum antimicrobial activity  
The present invention is directed to a novel class of antimicrobial agents called γ-AApeptides. The current invention provides various categories of γ-AApeptides, for example, linear γ-AApeptides,...
9498492 Compositions including triciribine and taxanes and methods of use thereof  
This application relates to combination therapies including triciribine and related compounds and taxanes and compositions with reduced toxicity for the treatment and prevention of tumors, cancer,...
US20160335223 METHODS AND SYSTEMS FOR COMPUTATION OF BILEVEL MIXED INTEGER PROGRAMMING PROBLEMS  
Techniques and systems are disclosed for improving the computation and solution of bilevel MIP problems. Various single-level reformulation techniques can be used to transform a bilevel MIP...
US20160331746 Sortilin-Binding Small Molecules for Increasing Glucose Uptake  
Various scaffolds of small molecules capable of binding to the active site of sortilin are identified by in silico methods. These scaffolds include norbornene anhydride amino acid adducts,...
US20160331314 MATERIALS AND METHODS FOR DETECTING AND MONITORING EDEMA AND RELATED CONDITIONS  
The subject invention provides a Coupled Domain Sensor (CDS) that can be used to, for example, evaluate hydration and occlusion of blood in patients with edema using electrical and optical...
9493825 Materials and methods for profiling microRNAs  
The present invention provides materials and methods for detecting, quantifying, and/or high-throughput-profiling microRNAs. Advantageously, the present invention is more sensitive and specific...
9493695 Method of encapsulating a phase change material with a metal oxide  
Storage systems based on latent heat storage have high-energy storage density, which reduces the footprint of the system and the cost. However, phase change materials (PCMs), such as NaNO3, NaCl,...
9492778 Metal-organic materials (MOMS) for CO2 adsorption and methods of using MOMS  
Embodiments of the present disclosure provide for hydrophobic multi-component metal-organic materials (MOMs) (also referred to as “hydrophobic MOM”), systems that exhibit permanent porosity and...
9492455 Methods of treating NFA-1 organism infection using apocynin  
Described herein are compounds and pharmaceutical formulations thereof that can be administered to a subject infected with or suspected of being infected with an organism having an Nfa-1 protein....
US20160329202 SYSTEMS AND METHODS FOR BUBBLE BASED ION SOURCES  
The present disclosure describes embodiments directed to a bubble based ion source system comprising an ion source configured to generate a plurality of ions, a heat source positioned above the...
9486626 Passive electric field focus system for in vivo and in vitro applications  
The present invention provides a system and method of directing, focusing, or concentrating electrical charges within a defined electric field so that these charges can be used to exert forces on...
9486522 Compositions including triciribine and trastuzumab and methods of use thereof  
This application relates to combination therapies including triciribine and related compounds and trastuzumab or a salt thereof and compositions with reduced toxicity for the treatment and...
9486492 Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof  
This application relates to combination therapies including triciribine and related compounds and bortezomib and derivatives thereof analogs and compositions with reduced toxicity for the...
9486470 Compositions including triciribine and one or more platinum compounds and methods of use thereof  
This application encompasses combination therapies including triciribine and related compounds and one or more platinum compounds and compositions with reduced toxicity for the treatment and...
US20160322566 METHOD OF MANUFACTURE FOR A PARTIALLY-SPRAYED LAYER ORGANIC SOLAR PHOTOVOLTAIC CELL  
The fabrication and characterization of large scale inverted organic solar array fabricated using all-spray process is disclosed. Solar illumination has been demonstrated to improve transparent...
US20160322093 Non-Volatile Flip-Flop with Enhanced-Scan Capability to Sustain Sudden Power Failure  
Non-volatile flip-flops (NVFFs) based circuitries and schemes that incorporate magnetic tunnel junctions (MTJs) are provided to ensure fast data storage and restoration from an intentional or...
US20160317487 METHODS OF SUSTAINING DIETARY KETOSIS AND ITS EFFECTS ON LIPID PROFILE  
The ketogenic diet (KD) has therapeutic implications in many disease states. It was hypothesized ketone precursor supplementation would elevate blood ketone levels to therapeutic ranges (2-7 mM)...
US20160317271 METHOD OF TREATING PELVIC PROLAPSE USING A SACROCOLPOPEXY/SACROCERVICOPEXY VAGINAL POSITIONING AND MESH RETENTION SYSTEM  
A method of treating pelvic prolapse is presented herein. Vaginal support device contains flat superior and inferior surfaces to facilitate affixing of mesh to vagina. Vaginal support device may...
9485037 Compact dual-channel transceivers  
In one embodiment, a dual-channel transceiver includes two harmonic repeaters each having a receive antenna, a transmit antenna, and a frequency multiplier connected to the antennas that is...
9481972 Systems and methods for splicing pile segments  
In one embodiment, a pile splicing system and method uses a pile segment adapted to form part of a spliced pile, the pile segment including an elongated concrete body having first and second ends,...
9481864 Conversion of non-neuronal cells into neurons  
The subject invention concerns materials and methods for conversion of non-neuronal cells into neurons. The subject invention also concerns methods for screening drugs and other compounds for...
9481821 Method of modulated exothermic chemical systems through phase change materials  
The chemical reactions modulation of temperature and dissipate heat through using phase change materials (PCM). Hydration of a mixture composed of encapsulated and/or non-encapsulated oxides such...
US20160312222 MANGANESE ION COATED NANOPARTICLES FOR DELIVERY OF COMPOSITIONS INTO THE CENTRAL NERVOUS SYSTEM BY NASAL INSUFFLATION  
The compositions and methods of the disclosure particularly target the divalent metal transporter expressed on olfactory nerve terminals to transport divalent cation-coated or cation-containing...
US20160310160 INCISION-LESS LAPAROSCOPIC INSTRUMENT  
A laparoscopic instrument is placed into the abdomen without the creation of a skin incision. The laparoscopic instrument includes a shaft that does not exceed 1.6 mm in diameter. The shaft has a...
9479375 Joint physical layer security and PAPR mitigation in OFDM systems  
Systems and methods for securing orthogonal frequency division multiplexing (OFDM) transmission of data are discussed herein. Transceivers can sense the signal strength of frequencies on an OFDM...
9476025 Ferromagnetic cell and tissue culture microcarriers  
A porous, collagen coated, ferromagnetic cell culture microcarrier, which is suitable for in vitro cell and tissue culture and which facilitates 3D multicellular construct generation. Also...
US20160303165 HUCBC TREATMENT OF AMYLOID-ASSOCIATED DISEASE  
Administration of human umbilical cord blood cells (HUCBC) or HUCBC-derived plasma is used to treat amyloid-based diseases, such as Alzheimer's disease, Huntington's disease, cerebral amyloid...
US20160302398 ANIMAL MODEL AND METHOD FOR STUDYING GENE-GENE INTERACTIONS  
The invention concerns a non-human animal model useful for sensitively studying gene-gene interactions over a wide genetic background; methods for producing the animal model; and methods for...
US20160297790 CYTOTOXIN COMPOUNDS AND METHODS OF ISOLATION  
The present invention concerns groups of compounds derived from tunicates of the Synoicum species, as well as to pharmaceutical compositions comprising these compounds, and uses thereof. Extracts...
9463190 Methods of treating disease-induced ataxia and non-ataxic imbalance  
Methods for treatment of disease-induced ataxia and non-ataxic imbalance are disclosed. The methods involve treating a patient with a compound having nicotinic acetylcholine receptor activity.
US20160287554 Small Molecule Metal-Activated Protein Inhibition  
A cancer treatment comprises the administration of a pro-drug compound identified by an in silico candidate identification screening. The pro-drug candidates are selected from a data base and...
9458086 Compositions and methods for adipocyte modulation  
Modified stilbenoids and formulations thereof are provided. The modified stilbenoids can include one or more amino or amino-alkyl substituents. The formulation can be for the treatment or...
9457040 Effective treatment of esophageal adenocarcinoma using triciribine and related compounds  
The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat esophogeal adenocarcinoma by one or a combination of (i) administering...
US20160280714 POLYHEDRAL CAGE-CONTAINING METALLOPORPHYRIN FRAMEWORKS, METHODS OF MAKING, AND METHODS OF USING  
Embodiments of the present disclosure provide compositions including metal-organic polyhedrons, metalloporphyrin framework structures, methods of making these, methods of using these, and the like.
9453049 Substrate-mimetic Akt inhibitor  
Disclosed herein is a species of peptide and non-peptide inhibitors of Akt, an oncogenic protein. Beginning with a residue of Akt target substrate GSK-3, the functional domains of the GSK-3...
9451890 Integrated vectorcardiogram system and method of use  
An integrated vectorcardiogram (VCG) device having 3 pairs of electrodes placed in three orthogonal directions with the capability to continuously measure the electrical activity of the heart. All...
US20160275678 IMAGE-BASED AUTOMATED MEASUREMENT MODEL TO PREDICT PELVIC ORGAN PROLAPSE  
A system and methodology for the automated localization, extraction, and analysis of MRI-based features with clinical information to improve the diagnosis of pelvic organ prolapse (POP). The...
US20160271213 REELIN RESCUES COGNITIVE FUNCTION  
Disclosed are methods of influencing, and enhancing, cognitive function by increasing, and/or preventing interference with, Reelin levels as well as Reelin signaling. Cognitive function is...
US20160268027 MAGNETO-DIELECTRIC POLYMER NANOCOMPOSITES  
In accordance with the present invention, novel superparamagnetic magneto-dielectric polymer nanocomposites are synthesized using a novel process. The tunability of the dielectric/magnetic...
9443662 Microstructured crystalline device in confined space, a dye-sensitized solar cell, and method of preparation thereof  
A method of forming an ordered nanorods array in a confined space is used to form a high surface area device where an ensemble of parallel trenches has micrometer dimensions for the width and...
9442116 Method of predicting chemotherapeutic responsiveness of cancer  
Disclosed is a method of predicting clinical tumor outcome by providing gene expression from a tumor sample. The method utilizes a novel genetic screen to identify genes that contribute to...
9439978 Multilayered magnetic micelle compositions and methods for their use  
Provided herein are compositions comprising a micelle having a hydrophobic superparmagnetic iron oxide nanoparticle (SPION) core, a first coating comprising a cationic polymer, and a second...
US20160260211 SYSTEMS AND METHODS FOR DIAGNOSING TUMORS IN A SUBJECT BY PERFORMING A QUANTITATIVE ANALYSIS OF TEXTURE-BASED FEATURES OF A TUMOR OBJECT IN A RADIOLOGICAL IMAGE  
An example method for diagnosing tumors in a subject by performing a quantitative analysis of a radiological image can include identifying a region of interest (ROI) in the radiological image,...
US20160258960 DETECTION OF CANCER BY ELEVATED LEVELS OF BCL-2  
The present invention relates to a method for the diagnosis, prognosis, and monitoring of cancer, such as early or late stage ovarian cancer, in a subject by detecting Bcl-2 in a biological sample...
US20160257712 INTEGRIN INTERACTION INHIBITORS FOR THE TREATMENT OF CANCER  
Integrin interaction inhibitors using a beta-turn promoter are described herein. These peptides are useful in treating cancer, such as multiple myeloma, by administering a therapeutically...
9437906 Electrode mesh galvanic cells  
The present invention is directed to the fabrication of thin aluminum anode batteries using a highly reproducible process that enables high volume manufacturing of the galvanic cells. A thin...
9434926 Graphene hydrogel and methods of using the same  
Provided herein are hydrogel compositions containing graphene, chitosan, a polyethylene (glycol) diacrylate (PEGDA). The hydrogel can optionally contain an N-isopropylacrylamide (NIPAM) (TPCG...