Patents and Patent Applications from University of South Alabama


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9840718 Minimal piggyBac vectors for genome integration  
Disclosed are genetic delivery systems that utilize genetic elements of the piggyBac family transposon system, and methods of introducing nucleic acid into target cells using the genetic delivery...
US20170341054 Modification Of Fibers With Nanostructures Using Reactive Dye Chemistry  
A fiber is provided as a substrate for a functional nanostructure (coated fiber), composed of (a) a fiber substrate; (b) a reactive dye conjugating moiety covalently bound to the fiber substrate;...
9827328 Combination therapy for treatment of cancer  
The present invention relates to methods and compositions for the treatment of cancer. Some embodiments include methods of treating cancer comprising administering a chemotherapeutic agent...
9827224 Methods and compositions for ameliorating pancreatic cancer  
Embodiments of the present invention include methods and compositions for ameliorating cancer. Some embodiments include methods and compositions for ameliorating pancreatic cancer targeting the...
9751044 Aqueous solutions of amine functionalized ionic compounds for carbon capture processes  
An aqueous ionic absorbent solution is disclosed containing (a) about 15 wt. % to about 80 wt. % of one or more diluents, based on the total weight of the aqueous ionic absorbent solution; and (b)...
US20170240715 Porous Nanocomposite and Related Method  
A nanocomposite including an array of extended length fibers with nanofibers oriented in transverse relation to the extended length fibers. The nanofibers are mechanically interlocked with the...
US20170204395 ESTABLISHMENT OF CELL LINES WITH ALTERED MITOCHONDRIAL DNA COPY NUMBER  
Reduced mitochondrial DNA copy number has been reported in numerous adverse clinical conditions, yet suitable tools for modulating mitochondrial DNA copy number have not been reported. The present...
US20170182718 APPARATUS AND METHOD FOR DIRECTIONAL ALIGNMENT OF NANOFIBERS IN A POROUS MEDIUM  
A method and apparatus for uniformly and directionally aligning and stretching nanofibers inside a porous medium is described. The nanofibers may include nanotubes, nanowires, long-chain polymer...
US20170145419 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER  
Some embodiments of the present invention relate to methods and compositions for treating cancer. More embodiments include methods and compositions for modulating the activity of the Hedgehog pathway.
US20170044548 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER  
Some embodiments of the present invention relate to agents and compositions for treating cancer. More embodiments include agents and compositions for modulating the activity of the Hedgehog pathway.
9540647 Methods and compositions for the treatment of cancer  
Some embodiments of the present invention relate to methods and compositions for treating cancer. More embodiments include methods and compositions for modulating the activity of the Hedgehog pathway.
US20160362694 METHODS AND COMPOSITIONS FOR THE DIAGNOSIS, CLASSIFICATION, AND TREATMENT OF CANCER  
Some embodiments of the present technology relate to methods and compositions for the diagnosis and treatment of cancer. Some embodiments include methods and compositions for the diagnosis and...
9464291 Methods and compositions for the treatment of cancer  
Some embodiments of the present invention relate to agents and compositions for treating cancer. More embodiments include agents and compositions for modulating the activity of the Hedgehog pathway.
9458456 Methods and compositions for the diagnosis, classification, and treatment of cancer  
Some embodiments of the present technology relate to methods and compositions for the diagnosis and treatment of cancer. Some embodiments include methods and compositions for the diagnosis and...
US20160250343 COMBINATION THERAPY FOR TREATMENT OF CANCER  
The present invention relates to methods and compositions for the treatment of cancer. Some embodiments include methods of treating cancer comprising administering a chemotherapeutic agent...
US20160235635 FORMULATIONS INCLUDING SILVER NANOPARTICLES AND METHODS OF USING THE SAME  
A method for reducing or inhibiting damage to skin is disclosed herein. In some embodiments, the damage is ultraviolet (UV) radiation-induced damage. In some embodiments, the method comprises...
US20160229918 TUMOR SELECTIVE ANTIBODIES SPECIFIC TO ONCOFETAL ANTIGEN/IMMATURE LAMININ RECEPTOR PROTEIN  
Disclosed are high affinity antibodies or antigen binding fragments thereof, which bind an epitope that lies within the C terminal region of oncofetal antigen (OFA)/immature laminin receptor...
US20160220532 METHODS AND COMPOSITIONS FOR AMELIORATING PANCREATIC CANCER  
Embodiments of the present invention include methods and compositions for ameliorating cancer. Some embodiments include methods and compositions for ameliorating pancreatic cancer targeting the...
9404102 Treatment of disease conditions via administration of DNA repair enzyme  
The present invention is directed to compositions and methods of preserving viability of islets of Langerhans for transplantation, and treating various disease and other abnormal or pathological...
US20160168342 Method For Manufacturing Nano-Structurally Aligned Multi-Scale Composites  
A method whereby nanostructures aligned within a matrix material to define an aligned admixture are transferred into a receiving porous medium while substantially maintaining the nanostructure...
US20160160235 MINIMAL PIGGYBAC VECTORS FOR GENOME INTEGRATION  
Disclosed are genetic delivery systems that utilize genetic elements of the piggyBac family transposon system, and methods of introducing nucleic acid into target cells using the genetic delivery...
US20160143912 TREATMENT AND DIAGNOSIS OF CANCER AND PRECANCEROUS CONDITIONS USING PDE10A INHIBITORS AND METHODS TO MEASURE PDE10A EXPRESSION  
Disclosed are methods for treating cancer and precancerous conditions with PDE10A specific inhibitors and diagnosis of neoplastic diseases based on elevated levels of PDE10A.
US20160115480 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER  
Some embodiments of the present invention relate to methods and compositions for treating cancer. More embodiments include methods and compositions for modulating the activity of the Hedgehog pathway.
9308276 Combination therapy for treatment of cancer  
The present invention relates to methods and compositions for the treatment of cancer. Some embodiments include methods of treating cancer comprising administering a chemotherapeutic agent...
9267934 Methods and compositions for ameliorating pancreatic cancer  
Embodiments of the present invention include methods and compositions for ameliorating cancer. Some embodiments include methods and compositions for ameliorating pancreatic cancer targeting the...
US20160016112 AQUEOUS SOLUTIONS OF AMINE FUNCTIONALIZED IONIC COMPOUNDS FOR CARBON CAPTURE PROCESSES  
An aqueous ionic absorbent solution is disclosed containing (a) about 15 wt. % to about 80 wt. % of one or more diluents, based on the total weight of the aqueous ionic absorbent solution; and (b)...
9205371 Method for improving total energy demand in a post-combustion carbon capture process with ionic absorbent  
Disclosed herein is a method for improving the total energy demand required to separate carbon dioxide (CO2) from an aqueous ionic absorbent solution in a post-combustion carbon capture process....
9186370 Methods and compositions for the treatment of cancer  
Some embodiments of the present invention relate to methods and compositions for treating cancer. More embodiments include methods and compositions for modulating the activity of the Hedgehog pathway.
9180403 Aqueous solutions of amine functionalized ionic compounds for carbon capture processes  
An aqueous ionic absorbent solution is disclosed containing (a) about 15 wt. % to about 80 wt. % of one or more diluents, based on the total weight of the aqueous ionic absorbent solution; and (b)...
US20150252436 METHODS AND COMPOSITIONS FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF CANCER  
The present invention relates to methods and compositions for diagnosing and treating cancer, such as breast cancer and skin cancer.
US20150241453 METHODS AND COMPOSITIONS FOR DETECTING ENDOMETRIAL OR OVARIAN CANCER  
Some embodiments of the present invention relate to methods and compositions for assessing the absence, presence, progression, or stage of cancer. In particular, methods and compositions for...
US20150218287 TUMOR SELECTIVE ANTIBODIES SPECIFIC TO ONCOFETAL ANTIGEN/IMMATURE LAMININ RECEPTOR PROTEIN  
Disclosed are high affinity antibodies or antigen-binding fragments thereof, which bind an epitope that lies within the C-terminal region of oncofetal antigen (OFA)/immature laminin receptor...
US20150185421 SPECTRAL ILLUMINATION DEVICE AND METHOD  
An illumination device and method including multiple illumination sources such as LEDs, lasing diodes or the like operatively connected to a multi-branch light guide adapted to collect and...
US20150118217 TREATMENT OF DISEASE CONDITIONS VIA ADMINISTRATION OF DNA REPAIR ENZYME  
The present invention is directed to compositions and methods of preserving viability of islets of Langerhans for transplantation, and treating various disease and other abnormal or pathological...
US20150068398 PROCESS FOR THE SEPARATION OF CARBON DIOXIDE FROM FLUE GAS  
A process and system for separating CO2 from a flue gas stream is disclosed. The process involves (a) contacting a flue gas stream containing water vapor and CO2 with an ionic absorbent under...
US20150044703 METHODS AND COMPOSITIONS FOR DETECTING ENDOMETRIAL OR OVARIAN CANCER  
Some embodiments of the present invention relate to methods and compositions for detecting the presence of cancer. In particular, methods and compositions for detecting endometrial cancer or...
8952193 Carbon dioxide scrubbing using ionic materials  
One aspect of the present invention relates to amine-functionalized task-specific ionic liquids (TSILs). In certain embodiments, the ionic liquids of the invention comprise beta-hydroxy amines,...
8911539 Process for the separation of carbon dioxide from flue gas  
A process and system for separating CO2 from a flue gas stream is disclosed. The process involves (a) contacting a flue gas stream containing water vapor and CO2 with an ionic absorbent under...
US20140364485 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER  
Some embodiments of the present invention relate to agents and compositions for treating cancer. More embodiments include agents and compositions for modulating the activity of the Hedgehog pathway.
US20140315853 METHODS, FORMULATIONS, AND KITS FOR RAPIDLY REPLETING FOLATE LEVELS IN WOMEN  
Disclosed are methods for rapidly repleting folate levels of a woman for whom there is reason to believe that she may be pregnant or of a woman who believes that she may soon become pregnant. One...
8865160 Treatment of disease conditions via administration of DNA repair enzyme  
The present invention is directed to compositions and methods of preserving viability of islets of Langerhans for transplantation, and treating various diseases and other abnormal or pathological...
US20140309184 METHODS AND COMPOSITIONS FOR THE TREATMENT OF OVARIAN CANCER  
Embodiments of the present disclosure relate to methods and compositions for treating a subject with ovarian cancer. Some embodiments include treating a subject with a particular combination of...
US20140170054 Carbon Dioxide Scrubbing Using Ionic Materials  
One aspect of the present invention relates to amine-functionalized task-specific ionic liquids (TSILs). In certain embodiments, the ionic liquids of the invention comprise beta-hydroxy amines,...
8709405 Cancer vaccines containing epitopes of oncofetal antigen  
Disclosed are fragments of oncofetal antigen, otherwise known as immature laminin receptor protein that specifically stimulate one T cell subclass. The fragments may be formulated into...
US20140080760 COMBINATION THERAPY FOR TREATMENT OF CANCER  
The present invention relates to methods and compositions for the treatment of cancer. Some embodiments include methods of treating cancer comprising administering a chemotherapeutic agent...
8674135 Functionalized ionic liquids, and methods of use thereof  
One aspect of the present invention relates to ionic liquids comprising a pendant Bronsted-acidic group, e.g., a sulfonic acid group. Another aspect of the present invention relates to the use of...
US20140051635 COMBINATION THERAPY FOR TREATMENT OF CANCER  
The present invention relates to methods and compositions for treating cancer. Some embodiments include methods comprising increasing expression of a nucleic acid encoding secreted protein acidic...
US20140045920 METHODS AND COMPOSITIONS FOR THE DIAGNOSIS, CLASSIFICATION, AND TREATMENT OF CANCER  
Some embodiments of the present technology relate to methods and compositions for the diagnosis and treatment of cancer. Some embodiments include methods and compositions for the diagnosis and...
8598134 RNAi modulation of RSV, PIV and other respiratory viruses and uses thereof  
The present invention is based on the in vivo demonstration that RSV and PIV can be inhibited through intranasal administration of RNAi agents as well as by parenteral administration of such...
US20130281423 METHODS AND COMPOSITIONS FOR AMELIORATING PANCREATIC CANCER  
Embodiments of the present invention include methods and compositions for ameliorating cancer. Some embodiments include methods and compositions for ameliorating pancreatic cancer targeting the...
Matches 1 - 50 out of 157 1 2 3 4 >