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US20120053079 |
METHODS AND COMPOSITIONS FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF CANCER
The present invention relates to methods and compositions for diagnosing and treating cancer, such as breast cancer and skin cancer.
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US20120028358 |
METHOD FOR INCREASING RETROVIRAL INFECTIVITY
The present invention is directed to methods for enhanced retroviral delivery of a nucleic acid to a target cell in vitro, ex vivo or in vivo, which involves increasing infectivity of a retrovirus...
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US20110110908 |
TREATMENT OF DISEASE CONDITIONS VIA ADMINISTRATION OF DNA REPAIR ENZYME
The present invention is directed to compositions and methods of preserving viability of islets of Langerhans for transplantation, and treating various diseases and other abnormal or pathological...
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US20110021606 |
RNAi Modulation of RSV, PIV and Other Respiratory Viruses and Uses Thereof
The present invention is based on the in vivo demonstration that RSV and PIV can be inhibited through intranasal administration of RNAi agents as well as by parenteral administration of such...
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US20100228035 |
Functionalized Ionic Liquids, and Methods of Use Thereof
One aspect of the present invention relates to ionic liquids comprising a pendant Bronsted-acidic group, e.g., a sulfonic acid group. Another aspect of the present invention relates to the use of...
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US20100183643 |
Cancer vaccines containing epitopes of oncofetal antigen
Disclosed are fragments of oncofetal antigen, otherwise known as immature laminin receptor protein that specifically stimulate one T cell subclass. The fragments may be formulated into compositions...
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US20100183542 |
Synergism Between Activated Immune Cells and Conventional Cancer Therapies
The present invention relates to a composition, method and kit for treating cancer. The treatment comprises administering a pre-sensitizing agent to a tumor or subject, and administering a cancer...
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7750166 |
Ionic liquids containing a sulfonate anion
The present invention relates to novel ionic liquids comprising a docusate, docusate variant, or other sulfonate anion. The ionic liquids may be conveniently made via, for example, metathesis. The...
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7744838 |
Functionalized ionic liquids, and methods of use thereof
One aspect of the present invention relates to ionic liquids comprising a pendant Bronsted-acidic group, e.g., a sulfonic acid group. Another aspect of the present invention relates to the use of...
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7741113 |
Cell-specific molecule and method for importing DNA into osteoblast nuclei
A plasmid, viral or linear DNA molecule containing a nucleic acid sequence derived from the promoter region of the hCol1α2 gene, which is selectively transported into the nuclei of cells in the ...
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US20100152465 |
Functionalized Ionic Liquids, and Methods of Use Thereof
One aspect of the present invention relates to ionic liquids comprising a pendant Bronsted-acidic group, e.g., a sulfonic acid group. Another aspect of the present invention relates to the use of...
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US20100150804 |
Carbon Dioxide Scrubbing Using Ionic Materials
One aspect of the present invention relates to amine-functionalized task-specific ionic liquids (TSILs). In certain embodiments, the ionic liquids of the invention comprise beta-hydroxy amines,...
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7718762 |
Cancer vaccines containing epitopes of oncofetal antigen
Disclosed are fragments of oncofetal antigen, otherwise known as immature laminin receptor protein that specifically stimulate one T cell subclass. The fragments may be formulated into compositions...
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7709635 |
Boronium-ion-based ionic liquids and methods of use thereof
One aspect of the present invention relates to “boronium” ions that are stable, hydrophobic, room-temperature ionic liquids. In certain embodiments, ionic liquids of the instant invention are rep...
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7674490 |
Food and vitamin preparations containing the natural isomer of reduced folates
A composition for human or animal consumption for supplying folate which includes a natural isomer of reduced folate, such as (6S)-tetrahydrofolic acid. 5-methyl-(6S)-tetrahydrofolic acid,...
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US20090200513 |
Ionic Liquids Containing a Sulfonate Anion
The present invention relates to novel ionic liquids comprising a docusate, docusate variant, or other sulfonate anion. The ionic liquids may be conveniently made via, for example, metathesis. The...
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US20080112866 |
Functionalized ionic liquids, and methods of use thereof
One aspect of the present invention relates to ionic liquids comprising a pendant Bronsted-acidic group, e.g., a sulfonic acid group. Another aspect of the present invention relates to the use of...
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7332335 |
Decreasing cell proliferation by decreasing levels of PP5
The invention provides a method of increasing expression of p21WAF1/Cip 1 in cells to decrease proliferation of the cells, the method comprising decreasing levels of PP5 protein in the cells. The...
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7208605 |
Functionalized ionic liquids, and methods of use thereof
One aspect of the present invention relates to ionic liquids comprising a pendant Bronsted-acidic group, e.g., a sulfonic acid group. Another aspect of the present invention relates to the use of...
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7172778 |
Food and vitamin preparations containing the natural isomer of reduced folates
A composition for human or animal consumption for supplying folate which includes a natural isomer of reduced folate, such as (6S)-tetrahydrofolic acid, 5-methyl-(6S)-tetrahydrofolic acid,...
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US20060287521 |
Boronium-ion-based ionic liquids and methods of use thereof
One aspect of the present invention relates to “boronium” ions that are stable, hydrophobic, room-temperature ionic liquids. In certain embodiments, ionic liquids of the instant invention are rep...
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7026344 |
Treating sickle cell disease
Sickle cell disease is treated by administering a 5-lipoxygenase inhibitor.
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US20050194561 |
Anionic-sweetener-based ionic liquids and methods of use thereof
One aspect of the present invention relates to ionic liquids comprising an anionic sweetener. Another aspect of the present invention relates to the use of an ionic liquid of the present invention...
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6808725 |
Preparations containing folic acid and a natural isomer of a reduced folate
Disclosed is a composition which includes one or more natural isomers of reduced folate selected from the group consisting of (6S)-tetrahydrofolic acid, 5-methyl-(6S)-tetrahydrofolic acid,...
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6673381 |
Uses for food and vitamin preparations containing the natural isomer of reduced folates
A composition for human or animal consumption for supplying folate which includes a natural isomer of reduced folate, such as (6S)-tetrahydrofolic acid. 5-methyl-(6S)-tetrahydrofolic acid,...
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6599742 |
Antisense oligonucleotide inhibition of human serine/threonine protein phosphatase gene expression
Oligonucleotides are provided which are targeted to nucleic acids encoding human serine/threonine protein phosphatases and which are capable of inhibiting protein phosphatase expression. Methods of...
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US20030124125 |
Oncofetal antigen specific T-lymphocyte mediated immune response: manipulation and uses of oncofetal antigen specific CD4, CD8 cytotoxic and suppressor T cells and interleukin-10
Disclosed are methods for detecting cancer or determining the success of cancer therapy in an individual. These methods are based on analyzing the presence or frequency of cloned oncofetal antigen...
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6562564 |
Decreasing cell proliferation by decreasing levels of PP5
The invention provides a method of increasing expression of p21WAF1/Cip 1 in cells to decrease proliferation of the cells, the method comprising decreasing levels of PP5 protein in the cells. The...
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6534060 |
Oncofetal antigen specific T-lymphocyte mediated immune response: manipulation and uses of oncofetal antigen specific CD4, CD8 cytotoxic and suppressor T cells and interleukin-10
The present invention provides a method of determining the success of a cancer therapy in an individual, comprising the step of measuring the frequency of occurence of an oncofetal antigen-specific...
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6512799 |
Digital communication system and method for increased bit rates
A digital communication system and method is provided for increasing bit-rates while maintaining the reliability of transmitted digital information and avoiding increased power demands. The...
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6495658 |
Comonomer compositions for production of imide-containing polyamino acids
Described are monomer compositions containing aspartic acid and other comonomers, such as monosodium aspartate, and methods for their production. The monomer compositions can be polymerized,...
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6451360 |
Method for treating a subject afflicted with intestinal malabsorption
A composition for human or animal consumption for supplying folate which includes a natural isomer of reduced folate, such as (6S)-tetrahydrofolic acid, 5-methyl-(6S)-tetrahydrofolic acid,...
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6429266 |
Thermal grafts of polyamides with pendant carboxylic acid groups, methods for producing the same, compositions containing the same, and methods of using the same
Heating an intimate mixture of: (a) a polyamide which contains pendant carboxylic acid groups; and (b) a compound which contains an amino group efficiently affords graft polymers with a high graft...
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6410743 |
Tetrahydronaphtalene derivatives and their use
Tetrahydronaphatalene derivatives, and compositions comprising the compounds. The tetrahydronaphatalene derivates are useful in inhibiting a rise in intracellular calcium mediated by an influx...
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6395768 |
Uses for indole-3-propionic acids and salts and esters thereof
The cytotoxic effects of amyloid beta protein on cells are prevented by contacting the cells with an effective amount of an indole-3-propionic acid or a salt or ester thereof. Furthermore, a...
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6335174 |
Oncofetal antigen specific t-lymphocyte mediated immune response: manipulation and uses of oncofetal antigen specific CD4, CD8 cytotoxic and suppressor T cells and interleukin-10
The present invention provides a method of determining the success of a cancer therapy in an individual, comprising the step of measuring the frequency of occurence of an oncofetal antigen-specific...
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6274615 |
Method for delaying the onset of alheimer's disease and for treatment or delaying the onset of other amyloidosis-related diseases/disorders
The present invention relates to a method of using melatonin to reduce, inhibit or reverse the formation of amyloid fibrils and amyloid or amyloid-like deposits. The present invention also relates...
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6254904 |
Food and vitamin preparation containing the natural isomer of reduced folates
A composition for human or animal consumption for supplying folate which includes a natural isomer of reduced folate, such as (6S)-tetrahydrofolic acid, 5-methyl-(6S)-tetrahydrofolic acid,...
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6235891 |
Glucocorticoid receptor agonist and decreased PP5
A composition comprises a glucocorticoid receptor agonist and a compound which decreases levels of active human serine/threonine protein phosphatase 5 protein in cells. The glucocorticoid receptor...
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6130207 |
Cell-specific molecule and method for importing DNA into a nucleus
The invention provides a cell-specific nuclear targeting molecule having a nucleic acid sequence which includes a binding site for a nuclear DNA binding protein expressed only in a specific cell...
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6087398 |
Sickle cell anemia treatment
The present invention provides a method of treating sickle cell anemia comprising the step of administering to an individual in need of said treatment a therapeutically acceptable dose of reducing...
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6020120 |
Use of N-acetylcysteine to store red blood cells and a method of aging red cells with nitrogen
The invention provides a method of preserving red blood cells. The method comprises treating the red blood cells with about 2 mM to about 35 mM of N-acetylcysteine. The invention further provides a...
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5997915 |
Compositions for human and animal consumption containing reduced folates and methods for making and using same
A composition for human or animal consumption for supplying folate which includes a natural isomer of reduced folate, such as (6S)-tetrahydrofolic acid, 5-methyl-(6S)-tetrahydrofolic acid,...
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5981691 |
Imide-free and mixed amide/imide thermal synthesis of polyaspartate
Thermal polymerization of a salt of aspartic acid affords polyaspartate directly without hydrolyzing polysuccinimide. Copolymerization of a salt of aspartic acid with aspartic acid itself affords a...
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5958964 |
Use of melatonin to prevent cytotoxic effects of amyloid beta protein
The present invention is directed to a method of preventing cytotoxic effects of amyloid beta protein on cells. The method comprises exposing the cells to an effective amount of melatonin. The...
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5948902 |
Antisense oligonucleotides to human serine/threonine protein phosphatase genes
Oligonucleotides are provided which are targeted to nucleic acids encoding human serine/threonine protein phosphatases and which are capable of inhibiting protein phosphatase expression. Methods of...
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5914242 |
Method for diminishing myocardial infarction using protein phosphatase inhibitors
Fostriecin and a compounds structurally related to fostriecin diminish myocardial infarction and delay the onset of cell injury in an ischemic heart. There is a strong correlation between...
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5908885 |
Polysuccinimide and polyaspartate as additives to cementitious materials
Polysuccinimide and/or polyaspartate, copolymers of succinimide and aspartate and the polymers cross-linked with a diamine are demonstrated to be enhancement agents for the preparation of...
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5831069 |
Antisense oligonucleotides against nonstructural proteins NS1 and NS2 of respiratory syncytial virus and uses thereof
The present invention provides an oligonucleotide having the nucleotide sequence complementary to the respiratory synctial virus nucleotide sequencenumber 98-116 of the respiratory synctial virus...
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5827705 |
Molecule and method for importing DNA into a nucleus
The invention provides a nuclear targeting molecule having a nucleic acid sequence which consists of SEQ ID NO:1 or a nuclear targeting portion of SEQ ID NO:1. The invention further provides a...
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