Patents and Patent Applications from University of Rochester


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US20180269644 METHOD AND APPARATUS FOR SPECTRAL NARROWING AND WAVELENGTH STABILIZATION OF BROAD-AREA LASERS  
Methods and apparatus for spectral narrowing and wavelength stabilization of broad-area lasers, such as an apparatus including a broad-area laser source configured to emit light along an emission...
US20180267326 METHODS AND SYSTEMS FOR CONTROLLING ANGULAR INTENSITY PATTERNS IN A REAL SPACE 3D IMAGE  
A system for displaying one or more images in three dimensions. The system has a three dimensional illumination volume containing a gas that emits one or more types of visible light when at...
US20180264083 Erythropoietin for Gastrointestinal Dysfunction  
This invention relates to treating gastrointestinal dysfunction with erythropoietin (EPO) or its analog.
US20180256703 Single-Cycle Virus for the Development of Canine Influenza Vaccines  
The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon...
US20180256503 COMPOSITION AND METHODS FOR THE TREATMENT OF PERIPHERAL NERVE INJURY  
Provided herein are methods of treating a peripheral nerve injury in a subject. The methods include administering to the subject at or near the site of the peripheral nerve injury an effective...
10073176 Superresolution imaging of scatterers in pulse-echo imaging with symmetric stabilized pulses  
Systems and methods of pulse-echo imaging using stabilized symmetric pulses are described. The systems and methods are based on the development of a class of symmetric, i.e., two sided, functions...
US20180246339 GREEN LASER FOR DISPLAY APPLICATIONS  
Methods and apparatus for producing high power lasers with reduced speckle are provided. Fiber and solid-state lasers comprising terbium-doped lasing material are provided. Embodiments are...
US20180245165 SURVIVAL PREDICTOR FOR DIFFUSE LARGE B CELL LYMPHOMA  
The invention provides methods and materials related to a gene expression-based survival predictor for DLBCL patients.
US20180243401 Live-Attenuated Vaccine Having Mutations in Viral Polymerase for the Treatment and Prevention of Canine Influenza Virus  
The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon...
US20180243082 VISION CORRECTION WITH LASER REFRACTIVE INDEX CHANGES  
Methods and systems wherein laser induced refractive index changes by focused femtosecond laser pulses in optical polymeric materials or optical tissues is performed to address various types of...
US20180236034 Compositions and Methods of Using Anti-Mullerian Hormone for Treatment of Infertility  
The present invention provides compositions and methods for the treatment of subjects with impaired fertility or at risk for impaired fertility. In certain aspects, the invention relates to...
US20180236000 PREVENTION AND TREATMENT FOR MICROBIAL INFECTIONS  
The present invention features a composition comprising zinc pyrithione and silver sulfiadizine, a formulation thereof and a method of treating microbial infection using the composition.
US20180231696 METHOD FOR MODIFYING THE REFRACTIVE INDEX OF AN OPTICAL MATERIAL AND RESULTING OPTICAL VISION COMPONENT  
A method for modifying the refractive index of an optical polymeric material. The method comprises continuously irradiating predetermined regions of an optical, polymeric material with femtosecond...
US20180228760 Antimicrobial Compositions Comprising Mupirocin and Neomycin  
The present invention features a composition comprising mupirocin and neomycin, a formulation thereof and a method of treating microbial infection using the composition.
US20180228467 Device, System and Method for Hemispheric Array Breast Imaging  
A device, system, and method for volumetric ultrasound imaging is described. The device and system include an array of transducer elements grouped in triangular planar facets and substantially...
10047443 Methods for producing hydrogen using nanoparticle-catalyst mixtures  
Methods for producing hydrogen using nanoparticles, a catalyst, and a source of electrons, such as bacteria and their nutrient source in a biological system, are carried out in an aqueous medium....
US20180223261 ATTENUATED INFLUENZA VACCINES AND USES THEREOF  
Provided herein are attenuated influenza viruses and methods of making attenuated influenza viruses.
US20180223256 MODIFIED T CELLS AND THEIR USES IN TREATING CANCER  
Provided herein are compositions and methods for treating cancer. The compositions include a modified T cell comprising a nucleic acid encoding a calcium translocating channelrhodopsin (CatCh)...
US20180220892 ASSESSMENT OF MICROVASCULAR DYSFUNCTION WITH SPECTRAL IMAGING  
A method for quantifying microvascular function in a patient includes stabilizing a test portion of the patent to analyze. A microvascular blood flow parameter is measured using a first spectral...
US20180219110 Low Dark Current, Resonant Cavity-Enhanced Infrared Photodetectors  
A resonant cavity-enhanced infrared photodetector has an absorber layer disposed between a first transparent layer and a second transparent layer within an optical cavity. The first transparent...
US20180214339 Methods, Devices and Systems for Orthoptics  
Provided herein is an orthoptic method of improving depth-perception in an individual. Devices, systems and kits for performing the present method are also provided.
US20180206979 Optical Material and Method for Modifying the Refractive Index  
A method for modifying the refractive index of an optical, polymeric material. The method comprises irradiating select regions of the optical, polymeric material with a focused, visible or near-IR...
10028931 Synergistic compositions for treating microbial infections  
Synergistic pharmaceutical compositions including an RNase P inhibitor and a tRNA synthetase inhibitor are provided, as well as methods for their use in treating infections. Also provided herein...
US20180188257 SEPTIN PROTEINS AS NOVEL BIOMARKERS FOR DETECTION AND TREATMENT OF MÜLLERIAN CANCERS  
Provided herein, inter alia, are septin family proteins as novel biomarkers for the detection of Müllerian cancers such as ovarian, fallopian tube, primary peritoneal, endometrial and uterine...
10013348 Parallel memory allocator employing liveness metrics  
A liveness-based memory allocation module operating so that a program thread invoking the memory allocation module is provided with an allocation of memory including a reserve of free heap slots...
10005883 Shape memory polymers and methods of making and use thereof  
Described are shape memory polymers and methods of making shape memory polymers and actuators from the shape memory polymers.
10004701 Methods and compositions for treating infection  
Provided herein are compositions and methods for treating or preventing infection.
10004438 Implantable real-time oximeter to determine potential strokes and post-traumatic brain-injury complications  
A first embodiment of the implantable real-time oximeter of the present invention is attached around a blood vessel near the site of a likely stroke to monitor large and medium size cerebral...
US20180173009 OPTICAL DEVICE FOR OFF-AXIS VIEWING  
An optical device for off-axis viewing includes a contact lens adapted for human eye wear. The contact lens includes a diffraction grating written into or on the contact lens. A peripheral light...
US20180171288 METHODS OF TREATING CANCER  
Compositions and methods of treating a subject with cancer are described. The methods include administering to the subject a therapeutically effective amount of a pharmaceutical composition...
US20180166593 Multiple Layer Optics for Light Collecting and Emitting Apparatus  
A light guide includes a light guide layer having a transversely oriented side-end surface that forms a primary output aperture (exit) for light traveling in a forward propagation direction out of...
US20180163209 MODULATION OF DYSTROPHIA MYOTONICA-PROTEIN KINASE (DMPK) EXPRESSION  
Provided herein are methods, compounds, and compositions for reducing expression of a DMPK mRNA and protein in an animal. Also provided herein are methods, compounds, and compositions for...
9993429 Composition and methods for the treatment of peripheral nerve injury  
Provided herein are methods of treating a peripheral nerve injury in a subject. The methods include administering to the subject at or near the site of the peripheral nerve injury an effective...
9993168 Implantable pressure monitor  
There is provided an implantable pressure monitor having a fluid sack in contact with a body part of a patient where the fluid sack is retained to the body part by a pressure monitor housing that...
US20180155492 SHAPE-MEMORY POLYMERS AND METHODS OF MAKING AND USE THEREOF  
Described are shape-memory polymers that have a composite prepolymer crosslinked with a stoichiometric amount of a multifunctional crosslinker, the composite prepolymer having a branched or...
US20180153990 PCA1 PROTEIN AND METHODS OF TREATING PNEUMOCYSTIS PNEUMONIA INFECTION  
The present invention relates to a method of treating Pneumocystis pneumonia infection in a subject. This method involves administering to a subject having a Pneumocystis pneumonia infection one...
9988448 DC-STAMP antibodies  
Provided herein are antibodies that specifically bind an epitope of DC-STAMP. Specifically, provided herein are monoclonal antibodies that bind an epitope of DC-STAMP, wherein the epitope...
US20180149665 Metabolic Biomarkers for Memory Loss  
The present invention relates to methods of determining if a subject has an increased risk of suffering from memory impairment. The methods comprise analyzing at least one plasma sample from the...
US20180147256 MEANS AND METHODS FOR TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY (FSHD).  
The invention is related to facioscapulohumeral muscular dystrophy (FSHD) and in particular therapeutic means and methods for the treatment of the disease. In one aspect the invention provides a...
US20180143194 COMPOSITIONS AND METHODS FOR DETECTING STAPHYLOCOCCOUS INFECTIONS  
Provided herein are compositions and methods for detecting and/or diagnosing a Staphylococcus aureus (S. aureus) infection in a subject. It is a surprising finding of the present invention that an...
US20180136039 IMAGING SPECTROMETER WITH FREEFORM SURFACES  
Expanded performance opportunities for imaging spectrometers are described using φ-polynomial freeform surfaces in reflective and diffractive optics. The imaging spectrometers are generally of a...
9970059 Survival predictor for diffuse large B cell lymphoma  
The invention provides methods and materials related to a gene expression-based survival predictor for DLBCL patients.
US20180127468 ANTI-HIV PEPTIDES  
The present disclosure provides simple β-hairpin peptides in linear and cyclic form that specifically bind to HIV-1 Trans-Activation Response element (HIV-1 TAR), as well as compositions and use...
9964444 Imaging spectrometer design tool for evaluating freeform optics  
A full-field display for spectrally dispersive imaging optics, particularly as a design tool for evaluating optical designs including designs with freeform optical surfaces, includes a ray tracing...
US20180113310 FREEFORM NANOSTRUCTURED SURFACE FOR VIRTUAL AND AUGMENTED REALITY NEAR EYE DISPLAY  
A near eye display includes at least one of a combiner, a secondary mirror, and a waveguide having a freeform nanostructured surface. The freeform nanostructured surface encompasses a freeform...
9949950 Compositions and methods for controlled localized delivery of bone forming therapeutic agents  
The present invention provides compositions and methods for providing controllable local delivery of a therapeutic agent to promote bone formation. In certain embodiments, the invention is used as...
9943585 Methods and compositions related to reorganization of arenavirus genome for development of novel arenavirus live-attenuated vaccines (LAV)  
Disclosed are compositions and methods related to recombinant arenaviruses and their use in vaccines for the treatment or prevention of an arenavirus infection.
9939558 Method for modifying the refractive index of an optical material and resulting optical vision component  
A method for modifying the refractive index of an optical polymeric material. The method comprises continuously irradiating predetermined regions of an optical, polymeric material with femtosecond...
US20180086878 SHAPE-MEMORY POLYMERS AND METHODS OF MAKING AND USE THEREOF  
Described are shape-memory polymers that have a branched or telechelic prepolymer having a low polydispersity crosslinked with a stoichiometric amount of a multifunctional crosslinker. Also...
9925038 System and method for designing wavefront-guided ophthalmic lenses  
The design of a corrective lens combines the measured aberration with decentration and rotation of the lens to design customized optical surface profiles to reliably achieve vision correction.