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US20110104694 |
COMPOSITIONS AND METHODS FOR DETECTING CANCER
The present invention provides methods and compositions involving detecting the presence of and/or assessing the risk of cancer in a subject. These methods include methods of detecting and...
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US20110104213 |
Porous Biomolecule-Containing Metal-Organic Frameworks
The present invention relates to compositions including porous biomolecule-containing metal-organic frameworks and methods for their preparation. The porous biomolecule-containing metal-organic...
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US20110103312 |
Methods and Apparatus for Switching A Transponder To an Active State, and Asset Management Systems Employing Same
A transponder that may be used as an RFID tag includes a passive circuit to eliminate the need for an “always on” active RF receiving element to anticipate a wake-up signal for the balance of the...
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US20110101788 |
Wireless Energy Transfer System
A wireless energy transfer system includes a first energy transfer unit having at least one resonant frequency, a second energy transfer unit having the at least one resonant frequency, and a load....
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US20110098651 |
DISSOLVABLE MICRONEEDLE ARRAYS FOR TRANSDERMAL DELIVERY TO HUMAN SKIN
A method of forming a microneedle array can include forming a sheet of material having a plurality of layers and micromilling the sheet of material to form a microneedle array. At least one of the...
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7933861 |
Process data warehouse
Systems and/or methods are presented that can efficiently analyze and summarize large collections of data. A summarization component can employ mapping rules to map received data into specified...
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US20110091908 |
EARLY PROSTATE CANCER ANTIGEN-2: A NOVEL SERUM SPECIFIC MARKER FOR PROSTATE CANCER DETECTION
Early Prostate Cancer Antigen-2 (EPCA-2) is a prostate cancer biomarker, newly identified via proteomics-based examination of alterations in nuclear structure. EPCA-2 shows a higher overall...
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US20110086909 |
SYNTHESIS OF FR901464 AND ANALOGS WITH ANTITUMOR ACTIVITY
The present invention provides novel analogs of FR901464, as well as an improved methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer activity and are...
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US20110086894 |
BIOMARKERS FOR THE DIAGNOSIS OF ALS
Methods for determining the onset of ALS in a subject are provided. One method includes analyzing a sample obtained from the subject for the presence or amount of one or more biomarkers indicative...
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7920736 |
Methods and systems for imaging cells
The invention generally provides methods and systems for determining characteristics of cellular structures. The methods include non-invasive, non-perturbing, automatable, and quantitative methods...
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7907769 |
Image-based methods for measuring global nuclear patterns as epigenetic markers of cell differentiation
The invention provides methods for determining the differentiation state of cells. The methods include non-invasive, non-perturbing, automatable, and quantitative methods of analysis of cell...
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7906110 |
Rapid preparation of stem cell matrices for use in tissue and organ treatment and repair
The invention is directed to preparation of stem cell and physiologically acceptable matrix compositions. Compared with previous tissue engineering materials, the stem cell-matrix compositions of...
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US20110060461 |
Cortical Control of a Prosthetic Device
A methodology for using cortical signals to control a multi jointed prosthetic device for direct real-time interaction with the physical environment, including improved methods for calibration and...
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7902272 |
Highly diffracting, color shifting, polymerized crystalline colloidal arrays of highly charged polymer spheres, paints and coatings and processes for making the same
One aspect of the present disclosure is directed towards a new film forming paint that Bragg diffracts light in the visible and NIR spectral regions. The paint may be comprised of highly charged...
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7897569 |
Use of HMGB fragments as anti-inflammatory agents
Compositions and methods are disclosed for inhibiting the release of a proinflammatory cytokine from a vertebrate cell, and for inhibiting an inflammatory cytokine cascade in a patient. The...
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7897326 |
Peroxisome-proliferator activated receptor-alpha agonists for organ preservation
Methods and compositions for reducing, preventing or reversing organ damage and/or enhancing organ preservation by administration of a peroxisome-proliferator activated receptor-alpha (PPARα) ...
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US20110045507 |
FSTL-1 AS A BIOMAKER OF INFLAMMATION
The invention provides methods and kits for diagnosing severity of particular types of inflammatory diseases, such as rheumatic diseases, by assessing protein levels of follistatin-like protein 1...
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7887792 |
Muscle-derived cells (MDCs) for treating muscle- or bone-related injury or dysfunction
The present invention provides muscle-derived cells, preferably myoblasts and muscle-derived stem cells, genetically engineered to contain and express one or more heterologous genes or functional...
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7884085 |
Delivery of AS-oligonucleotide microspheres to induce dendritic cell tolerance for the treatment of autoimmune type 1 diabetes
AS-oligonucleotides are delivered in microsphere form in order to induce dendritic cell tolerance, particularly in the non-obese-diabetic (NOD) mouse model. The microspheres incorporate antisense...
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7882909 |
Personal vehicle
A personal vehicle comprises a frame with a seat, two large, non-drive wheels connected by an axle at one end of the frame, an elongated swing arm attached to the axle, a pair of caster wheels...
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7878978 |
Use of relaxin to increase arterial compliance
The present invention provides methods for increasing arterial compliance. The methods generally involve administering to an individual in need thereof an effective amount of relaxin. The present...
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7876225 |
Methods and apparatus for switching a transponder to an active state, and asset management systems employing same
A transponder that may be used as an RFID tag includes a passive circuit to eliminate the need for an “always on” active RF receiving element to anticipate a wake-up signal for the balance of the...
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US20110012728 |
Sensor and System to Detect Bridge Scour
A system for detecting scour associated with a structure having a part thereof extending into a bed of material located under a body of water is provided. The system comprises a sensor unit buried...
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7872027 |
Low molecular weight Myc-max inhibitors
Compounds and compositions for interfering with the association of Myc and Max are described herein. These compounds and compositions are useful in methods inhibiting growth or proliferation of a...
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7867752 |
Method and apparatus for holding cells
The present invention pertains to an apparatus for holding cells. The apparatus comprises a mechanism for incubating cells having a dynamically controlled environment in which the cells are grown,...
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7858657 |
Wortmannin analogs and methods of using same in combination with chemotherapeutic agents
Novel wortmannin analogs and their use in inhibiting PI-3-kinase activity in mammals and the treatment or prevention of cancer and tumor formation in a subject are described herein. Preferably, the...
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7858071 |
Biomarkers for amyotrophic lateral sclerosis
The invention provides a method for diagnosing amyotrophic lateral sclerosis (ALS) in a subject, a method for assessing the effectiveness of a drug in treating ALS, and a method for determining the...
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US20100323029 |
FIVE-COORDINATE NEUROGLOBIN AND USE THEREOF AS A BLOOD SUBSTITUTE
Described herein is the finding that a mutant form of human neuroglobin (H64L) with a stable five-coordinate geometry reduces nitrite to nitric oxide approximately 2000-times faster than the wild...
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US20100322909 |
TH1-ASSOCIATED MICRORNAS AND THEIR USE FOR TUMOR IMMUNOTHERAPY
Described herein is the identification of miRNAs (miRs) that are up-regulated in Th1 cells compared to Th2 cells (referred to herein as Th1-associated miRs). In particular, the miR-17-92 gene...
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7854920 |
Thioflavin derivatives for use in antemortem diagnosis of alzheimer's disease and in vivo imaging and prevention of amyloid deposition
This invention relates to novel thioflavin derivatives, methods of using the derivatives in, for example, in vivo imaging of patients having neuritic plaques, pharmaceutical compositions comprising...
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7851144 |
Compositions and methods for detecting cancer
The present invention provides methods and compositions involving detecting the presence of and/or assessing the risk of cancer in a subject. These methods include methods of detecting and...
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US20100298352 |
SMALL MOLECULE INHIBITORS OF CANCER STEM CELLS
A method of inhibiting a carcinoma in a subject, comprising administering to the subject at least one therapeutic agent that selectively targets carcinoma stem cells. Illustrative carcinoma stem...
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US20100297158 |
ANTICANCER VACCINE AND DIAGNOSTIC METHODS AND REAGENTS
The invention provides a method for vaccinating a patient against a malignancy comprising introducing a protein or peptide comprising of all or an immunogenic fragment of a cyclin protein into the...
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7838251 |
Nuclear matrix protein alterations associated with colon cancer and colon metastasis to the liver, and uses thereof
Proteins useful in the diagnosis of proliferative disorders of the colon are present in nuclear matrix protein preparations and can be characterized by molecular weight, isoelectric point, and...
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US20100285489 |
METHOD FOR DIAGNOSING RENAL DISEASES OR PREDISPOSITIONS
The invention provides a method of diagnosing a disease or a predisposition to contract a disease by assaying for mutations of uromodulin (UMOD) within a test subject or patient. The presence of a...
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7829536 |
Method of treating lymphedema comprising administering VEGF-D
The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects.
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7829097 |
Use of HMGB1 for protection against ischemia reperfusion injury
Methods and compositions are disclosed for protecting an organ or tissue from inflammation and organ injury following ischemia, reperfusion, and trauma through the administration of an HMGB1...
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US20100279969 |
AZIDO PURINE NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS
The present invention is directed to compounds, compositions and methods for treating or preventing viral infections, in particular, HIV, HBV, and HCV, in human patients or other animal hosts. The...
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7825807 |
Transponder networks and transponder systems employing a touch probe reader device
Transponder networks and transponder systems are provided which help to overcome the issues presented to transponders systems by FCC power limitations. One embodiment provides a transponder network...
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7825267 |
Synthesis of FR901464 and analogs with antitumor activity
The present invention provides novel analogs of FR901464, as well as an improved methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer activity and are...
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US20100260855 |
DELIVERY OF AS-OLIGONUCLEOTIDE MICROSPHERES TO INDUCE DENDRITIC CELL TOLERANCE FOR THE TREATMENT OF AUTOIMMUNE TYPE 1 DIABETES
AS-oligonucleotides are delivered in microsphere form in order to induce dendritic cell tolerance, particularly in the non-obese-diabetic (NOD) mouse model. The microspheres incorporate antisense...
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US20100256943 |
CONFIGURATION OF INITIAL CONTROL PARAMETERS IN PHOTODETECTORS FOR MULTI-COLOR FLOW CYTOMETRY
System(s) and method(s) for initial configuration of photodectors in a multi-color flow cytometer to mitigate spectral compensation. Configuration is iterative and automated, and optimizes...
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7806589 |
Bi-plane X-ray imaging system
A high-speed biplane radiography system for in-vivo assessment of joint function is provided. The system can acquire stereo-pair radiographic images at rates from 30-4000 frames per second of...
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US20100233752 |
METHOD FOR DIAGNOSIS AND MONITORING OF DISEASE ACTIVITY AND RESPONSE TO TREATMENT IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) AND OTHER AUTOIMMUNE DISEASES
The present invention provides methods of diagnosing and monitoring systemic lupus erythematosus and drug-induced lupus erythematosus by measuring cell-based complement activation products in a...
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US20100233138 |
Vocal Cord Augmentation Utilizing Muscle-Derived Progenitor Compositions, and Treatments Thereof
The present invention provides muscle-derived progenitor cells that show long-term survival following transplantation into body tissues and which can augment vocal cord tissue following...
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US20100231218 |
Method for Producing A Magnetic Resonance Image of an Object Having a Short T2 Relaxation Time
A method for producing a magnetic resonance image using an ultra-short echo time. The method includes applying a pulse sequence to an object, detecting a spirally encoded and phase encoded magnetic...
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7792392 |
Fiber optic gas sensor
A gas sensor includes an in-fiber resonant wavelength device provided in a fiber core at a first location. The fiber propagates a sensing light and a power light. A layer of a material is attached...
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7791557 |
Multiple antenna energy harvesting
Energy harvesting circuits and associated methods are provided that employ multiple antennas to optimize the amount of energy that is harvested while at the same time making efficient use of tag...
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7790037 |
Separation of compounds using tagging moieties including varying numbers of repeat units
A method of separating compounds, includes: a. tagging at least a first organic compound with a first tagging moiety to result in a first tagged compound; b. tagging at least a second organic...
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7781164 |
Method for diagnosing renal diseases or predispositions
The invention provides a method of diagnosing a disease or a predisposition to contract a disease by assaying for mutations of uromodulin (UMOD) within a test subject or patient. The presence of a...
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