Patents and Patent Applications from University of Oklahoma


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US20120070859 BACTERIAL CELLS, OPTIMIZED NUCLEOTIDE SEQUENCES AND METHODS FOR IMPROVED EXPRESSION OF RECOMBINANT CLOSTRIDIUM DIFFICILE TOXIN B  
In some embodiments, the present invention provides isolated nucleotide sequences that encode Clostridium difficile toxin B, wherein the isolated nucleotide sequences have been optimized for...
US20120055528 THERMOELECTRIC MATERIALS  
A thermoelectric material having a high ZT value is provided. In general, the thermoelectric material is a thin film thermoelectric material that includes a heterostructure formed of IV-VI...
8128939 Mutants of cholesterol-dependent cytolysins and uses thereof  
Mutants of cholesterol-dependent cytolysins comprising at least one amino acid substitution in at least one of Loop 1, Loop 2, or Loop 3 of Domain 4, nucleic acids encoding such polypeptide...
8119618 Compositions and methods for the treatment of inflammatory diseases  
Inflammatory bowel diseases are represented by two idiopathic disorders, which include ulcerative colitis and Crohn's disease. Ulcerative colitis is restricted to the colon and involves uncertain...
8101159 In vivo methods of identifying compounds which target suppressed cancer cells  
In vitro and in vivo methods for identifying compounds capable of targeting suppressed cancer cells such as micrometastatic cells. The in vitro method includes the steps of comparing the response...
8100840 Remote cervical dilation monitoring system and method  
A method of monitoring the cervical dilation of a pregnant female, comprising the steps of receiving cervical dilation data generated by a cervical dilation monitor having a sensor including a coil...
8088604 Production of defined monodisperse heparosan polymers and unnatural polymers with polysaccharide synthases  
The present invention relates to methodology for polymer grafting by a polysaccharide synthase and, more particularly, polymer grafting using the hyaluronate or chondroitin or heparin/heparosan...
8075786 Acoustic/pressure wave-driven separation device  
An acoustic/pressure wave-driven device for separating a first component from a mixture of the first component and a second fluid component. The device comprises a rich reservoir, a lean reservoir,...
8075139 3D light surface display  
A light surface display for providing a three-dimensional image including a plurality of particles suspended within a volumetric display. A first projection system projects sequential slices of...
US20110293369 Method and apparatus for compaction of roadway materials  
A method of compacting a roadway section includes entering initial input parameters into a compaction analyzer. A plurality of passes is made with a roller over a portion of the roadway section and...
US20110241153 METHOD FOR THIN FILM THERMOELECTRIC MODULE FABRICATION  
Methods of fabrication of a thermoelectric module from thin film thermoelectric material are disclosed. In general, a thin film thermoelectric module is fabricated by first forming an N-type thin...
8021874 Very long chain polyunsaturated fatty acids, methods of production, and uses  
The present invention relates to processes for production of Very Long Chain Polyunsaturated Fatty Acids (VLC-PUFAs). The present invention also relates to compositions (e.g., nutritional...
8020508 Methods and apparatus for depositing nanoparticles on a substrate  
The present invention is a process for uniformly depositing nanomaterials having particles smaller than 1 μm (i.e., nanoparticles) onto a surface of a base material (substrate or surface). The ...
7998490 Genes of an otitis media isolate of nontypeable Haemophilus influenzae  
The invention relates to the polynucleotide sequence of a nontypeable stain of Haemophilus influenzae (NTHi) and polypeptides encoded by the polynucleotides and uses thereof. The invention also...
7998141 Irrigated catheter and method, in particular for ablation and like techniques  
The invention relates to a variety of catheters provided with an elongate body with an electrically conductive first end. Wherein through said elongate body at least one conductive wire extends...
7995277 Apparatus for controlling energy through a skylight  
An apparatus for controlling energy from a skylight of a structure including a plurality of vanes positioned beneath the skylight and angularly adjustable to control solar radiation entering the...
7984638 Gas chromatograph oven  
A gas chromatograph oven including a housing, a capillary tube and a thermal control assembly. The housing defining a capillary tube receiving space and having at least one outlet port to permit...
US20110176723 Motion Correction in Cone-Beam CT by Tracking Internal and External Markers Using Cone-Beam Projection From a kV On-Board Imager: Four-Dimensional Cone-Beam CT and Tumor Tracking Implications  
An apparatus comprising a processor configured to receive a sequence of Cone-Beam Computed Topology (CBCT) projections of a three dimensional (3D) object over a scanning period, wherein the 3D...
US20110171646 MICRORNA EXPRESSION PROFILE ASSOCIATED WITH PANCREATIC CANCER  
Methods are provided for diagnosing whether a subject has, or is at risk of developing, pancreatic cancer. The methods include measuring the level of at least one miR gene product in a biological...
7975556 Sensor-enabled geosynthetic material and method of making and using the same  
The present invention is directed to a sensor-enabled geosynthetic material for use in geosynthetic structures, a method of making the sensor-enabled geosynthetic material, and a method of...
7960548 Keratinocyte growth factor receptor—tyrosine specific inhibitors for the prevention of cancer metastatis  
Compounds and methods for treating, inhibiting, or delaying the onset of cancer in a subject by administering a therapeutically effective amount of a keratinocyte growth factor receptor tyrosine...
7956044 Compositions comprising inhibitors of RNA binding proteins and methods of producing and using same  
Compositions for inhibiting RNA binding proteins, as well as methods of producing and using same, are disclosed herein.
7939606 Polyalkenoate cement compositions and methods of use in cementing applications  
Methods and compositions for cementing applications. In one embodiment, the present invention provides a method of cementing comprising the steps of: providing a cement composition that comprises:...
7923098 Low-defect-density crystalline structure and method for making same  
A low-defect-density crystalline structure comprising a first crystalline material, a layer of second crystalline material epitaxially grown on the first crystalline material, and a layer of third...
7919417 Hydrophobic and oleophobic material  
The present invention relates in general to a method and variations thereof for making an article, such as cloth, water repellent and/or water resistant (i.e., hydrophobic) as well as oil repellent...
US20110071117 COMBINATIONS OF ANTIOXIDANTS AND ANTI-INFLAMMATORY DRUGS IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE  
Disclosed herein are compositions comprising 5-aminosalicylic acid (5-ASA), or a pharmaceutically acceptable salt thereof and an antioxidant, or a pharmaceutically acceptable salt thereof. Also...
7906177 Method for making an article hydrophobic and oleophobic as well as articles made therefrom and their use  
The present invention relates in general to a method and variations thereof for making an article, such as cloth, water repellent and/or water resistant (i.e. hydrophobic) as well as oil repellent...
7903977 Method for polarization-based intrusion monitoring in fiberoptic links  
A fiber optic communication system including a fiber optic link, a transmitter system and a receiver system. The transmitter system includes a laser source producing a light beam, and a...
7902166 Compositions comprising inhibitors of RNA binding proteins and methods of producing and using same  
Compositions for inhibiting RNA binding proteins, as well as methods of producing and using the same, are disclosed herein.
7893934 Three-dimensional finite element modeling of human ear for sound transmission  
A finite element model of an ear stored on a computer readable medium having logic representing a three-dimensional geometric model of the ear; logic for meshing individual anatomical structures of...
7893027 Treatment of ocular wounds and ulcers  
A method for treating ocular conditions such as bacterial keratitis, bacterial conjunctivitis, corneal ulcers and wounds, endophthalmitis, and blebitis in mammals, by using a native, synthetic, or...
7879403 Method for making an article water resistant and articles made therefrom  
The present invention relates in general to a method and variations thereof for making an article such as cloth water repellent and/or water resistant. In particular, the method involves the...
7875276 Urinary tract tissue graft compositions and methods for producing same  
A method for providing a urinary tract tissue graft composition includes providing a segment of small intestinal submucosa and isolating and culturing at least one multipotent cell type from a...
7860563 Cardiac neuromodulation and methods of using same  
The present invention relates in general to methodologies for the treatment quenching preconditioning and communication between the intrinsic cardiac nervous system and an electrical stimulus. In...
7858913 Light surface display for rendering a three-dimensional image  
A light surface display for providing a three-dimensional image including a plurality of particles suspended within a volumetric display. A first projection system projects sequential slices of...
US20100310569 Genes of an Otitis Media Isolate of Nontypeable Haemophilus Influenzae  
The invention relates to the polynucleotide sequence of a nontypeable stain of Haemophilus influenzae (NTHi) and polypeptides encoded by the polynucleotides and uses thereof. The invention also...
7842387 Methods for growing and harvesting carbon nanotubes  
A method for directly growing carbon nanotubes, and in particular single-walled carbon nanotubes on a flat substrate, such as a silicon wafer, and subsequently transferring the nanotubes onto the...
7838249 Assays for rab5 activity  
Methods of determining intracellular levels of Rab5 activity are disclosed, as well as fusion proteins utilized in such methods and recombinant constructs encoding such fusion proteins. The fusion...
7830257 Long-range cattle identification system  
A long-range cattle identification system used to monitor a plurality of animals. The system uses a plurality of electronic information tags that are attachable to animals. The electronic...
7829622 Methods of making polymer composites containing single-walled carbon nanotubes  
Methods of forming carbon nanotube-polymer composites comprising single-walled carbon nanotubes. The carbon nanotube-polymer composites comprise highly dispersed carbon nanotubes having high melt...
7819825 Remote cervical dilation monitoring system and method  
A cervical dilation monitor for measuring the dilation of a cervix and for providing cervical data to an external wireless unit. The cervical dilation monitor comprises a housing, a sensor, a...
7819795 Method and apparatus for improving hearing  
A system and method for affecting the function of a mammalian ear. The system and method uses an oscillating magnetic field to move nanospheres comprised of single-domain nanoparticles. In a...
7816709 Single-walled carbon nanotube-ceramic composites and methods of use  
Composites of single-walled carbon nanotubes (SWNTs) and a ceramic support (e.g., silica) comprising a small amount of catalytic metal, e.g., cobalt and molybdenum, are described. The particle...
7816086 Genes of an otitis media isolate of nontypeable Haemophilus influenzae  
The invention relates to the polynucleotide sequence of a nontypeable stain of Haemophilus influenzae (NTHi) and polypeptides encoded by the polynucleotides and uses thereof. The invention also...
7815635 Catheter and method, in particular for ablation and like technique  
The invention relates to a catheter, provided with an elongated body with an electrically conductive first end, wherein through said body at least one live wire extends which is connected to said...
7813899 Method and circuit for statistical estimation  
A method for determining a quality indication, such as a bit error rate or a signal to noise ratio, of a photonic signal is described. The photonic signal is sampled, and then an estimated quality...
7807644 Chimeric proteins with phosphatidylserine binding domains  
Chimeric proteins comprising soluble Tissue Factor (sTF) and another subunit (e.g., annexin V) are described. The proteins promote blood clotting and/or inhibit cancer by targeting sTF to specific...
7794726 Mutants of lysine decarboxylase, vaccines for periodontitis, and methods of use  
The present invention is directed to mutants of lysine decarboxylase, nucleic acids encoding the mutants, and vaccines comprising the mutants for inhibiting and reducing the development of...
7775965 Decellularized grafts from umbilical cord vessels and process for preparing and using same  
A tissue graft is disclosed that includes a decellularized umbilical vessel having a luminal surface and an ablumenal surface, wherein the decellularized umbilical vessel is prepared by an...
US20100203606 ISOLATION AND CHARACTERIZATION OF NOVEL CLOSTRIDIAL SPECIES  
A novel clostridia bacterial species (Clostridium ragsdalei, ATCC BAA-622/PTA-7826, “P11”) is provided. P11 is capable of synthesizing, from waste gases, products which are useful as biofuel. In ...
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