Patents and Patent Applications from University of Oklahoma


Match Document Document Title
US20170354476 SURGICAL CLEANING TOOL, SYSTEM, AND METHOD  
A surgical cleaning tool and method of cleaning a surgical tool. The surgical cleaning tool includes a shaft, a handle and an end portion. The shaft has a distal end and a proximal end. The handle...
9839690 Singlet oxygen-labile linkers and methods of production and use thereof  
Activatable compositions that include at least one functional moiety and at least one cleavable linker directly or indirectly linked to the at least one functional moiety are disclosed. The at...
US20170348264 Glutamate Treatment of Cardiovascular Disorders  
Compositions and methods for treating various cardiovascular disorders include targeted delivery of glutamate for impairing a targeted portion of the autonomic nervous system (ANS). Targeted...
9804171 Diagnostic method for pediatric acute-onset neuropsychiatric syndrome (PANS) and pediatric autoimmune neuropsychiatric disorder associated with streptococci infection (PANDAS)  
The present invention provides a panel of at least five clinical analyses or tests (using serum samples) to determine the risk of pediatric acute-onset neuropsychiatric syndrome (PANS) and/or...
9778357 Cylindrical polarimetric phased array radar  
A method of collecting data using a polarimetric phased array antenna is described. The method includes directing electromagnetic signals to selected panels of an array of panels so as to transmit...
9777052 R-spondin variants, compositions, and methods of use  
R-spondin variants comprising a ZNRF3 binding region of a first R-spondin and an LGR4 binding region of a second R-spondin are disclosed. Cell culture media and compositions containing the...
US20170260231 Substrates and Inhibitors of Prolyl Oligopeptidase and Methods of Use Thereof  
Inhibitors of fibroblast activation protein alpha (FAP) and Prolyl Oligopeptidase (POP) are disclosed, along with their use in various therapies related to conditions, diseases, and disorders...
US20170252454 Heparosan Polymers and Methods of Making and Using Same for the Enhancement of Therapeutics  
Compositions, methods, and systems are disclosed for the development and use of heparosan as a therapeutic modifying agent or vehicle which can modulate drug cargo pharmacokinetics and behavior...
US20170247732 Methods of Producing Testosteronan Polymers Using Testosteronan Synthase  
Testosteronan, a heparosan analog having the structure [-4-D-GlcUA-α1,4-D-GlcNAc-α1-]n, is produced by testosteronan synthase, a single protein that is a dual-action catalyst that utilizes...
9744235 Treatment of cardiovascular disorders with targeted nanoparticles  
Methods for treating various cardiovascular disorders include targeted delivery of calcium ions for permanently impairing a portion of the autonomic nervous system (ANS). Targeted delivery may be...
US20170236447 PRONUNCIATION AID  
The present disclosure provides methods, tools, kits and electronic systems for transcribing non-Chinese language sounds into sound-associated Chinese language characters. The methods, tools, kits...
9735955 Optical cryptography systems and methods  
Systems and methods for sharing data between a first node and second node are disclosed. The methods may include sharing a first initialization vector between a first node and a second node using...
US20170226490 HIGH ISOMEROHYDROLASE ACTIVITY MUTANTS OF MAMMALIAN RPE65  
Mutant mammalian RPE65 proteins and portions thereof, and nucleic acids encoding the mutants, for use in treating a condition related to retinal degeneration in a subject, the mutant mammalian...
US20170216581 Cardiac Neuromodulation and Methods of Using Same  
A method of treating heart failure in a patient is disclosed that includes implanting a stimulation device into the identified patient to electrically stimulate the spinal cord, and activating the...
US20170214214 HYBRID SEMICONDUCTOR LASER ABSENT A TOP SEMICONDUCTOR CLADDING LAYER  
In at least one embodiment, a semiconductor laser is constructed to have a waveguide core including an active region, a top cladding, and a bottom cladding. The top cladding is positioned above...
US20170208040 OPTICAL CRYPTOGRAPHY SYSTEMS AND METHODS  
Systems and methods for sharing data between a first node and second node are disclosed. The methods may include sharing a first initialization vector between a first node and a second node using...
US20170198325 HIGH MOLECULAR WEIGHT HEPAROSAN POLYMERS AND METHODS OF PRODUCTION OF USE THEREOF  
High molecular weight heparosan polymers are described, as are methods of producing and using the high molecular weight heparosan polymers.
US20170190803 Heparosan-Based Biomaterials and Coatings and Methods of Production and Use Thereof  
Biomaterial compositions that include an isolated heparosan polymer are disclosed, as well as kits containing such biomaterial compositions and methods of producing and using such biomaterial...
9695427 Methods of producing testosteronan polymers using testosteronan synthase  
Testosteronan, a heparosan analog having the structure [-4-D-GlcUA-α1,4-D-GlcNAc-α1-]n, is produced by testosteronan synthase, a single protein that is a dual-action catalyst that utilizes...
9688722 Substrates and inhibitors of prolyl oligopeptidase and methods of use  
Inhibitors of fibroblast activation protein alpha (FAP) and Prolyl Oligopeptidase (POP) are disclosed, along with their use in various therapies related to conditions, diseases, and disorders...
9687559 Heparosan polymers and methods of making and using same for the enhancement of therapeutics  
The present invention includes compositions, methods, and systems for the development and use of heparosan, a natural polymer related to heparin, as a new therapeutic modifying agent or vehicle...
9683933 Method and apparatus for detecting an analyte  
Disclosed herein are methods and mid-IR detection apparatus to measure analytes in gas or liquid phase. Solid state cooling of a crystalline lattice is effectively achieved with the controlled...
9675662 Compositions for inhibition of RNA polymerase I and methods of production and use thereof  
Compositions for inhibition of RNA Polymerase I include peptides of Rpa43. Methods of production and use thereof are also disclosed.
9663585 Anti-DCLK1 monoclonal antibodies and methods of production and use thereof  
Monoclonal antibodies against DCLK1 and conjugates containing these monoclonal antibodies are disclosed. Methods of producing and using these monoclonal antibodies are also disclosed.
US20170140645 Traffic monitoring system  
An automated computerized system comprises a computer system executing traffic monitoring software. The traffic monitoring software reads data corresponding to a magnetic field of a first vehicle...
US20170125979 Interband Cascade Light Emitting Devices  
An interband cascade (IC) light emitting device comprising a plurality of interband cascade stages, wherein at least one of the IC stages is constructed to have an electron injector made of one or...
9629914 Heparosan-based biomaterials and coatings and methods of production and use thereof  
Biomaterial compositions that include an isolated heparosan polymer are disclosed, as well as kits containing such biomaterial compositions and methods of producing and using such biomaterial...
9624283 Peptide compounds and methods of production and use thereof  
Peptide compounds based on the CAP37 protein are disclosed, along with methods for treating various infections, wounds, and conditions, and methods of promoting healing and acceptance of grafts,...
9611281 BODIPY derivatives and methods of synthesis and use thereof  
Derivatives of BODIPY (boron dipyrromethene difluoride) and their synthesis and use are disclosed.
9603945 Heparosan polymers and methods of making and using same for the enhancement of therapeutics  
Compositions, methods, and systems are disclosed for the development and use of heparosan, a natural polymer related to heparin, as a new therapeutic modifying agent or vehicle which can modulate...
9603896 Peptide compounds and methods of production and use thereof  
Peptide compounds based on the CAP37 protein are disclosed, along with methods for treating various infections, wounds, and conditions, and methods of promoting healing and acceptance of grafts,...
9601327 High-power electronic device packages and methods  
A high power electronic device package constructed to include a high power electronic device having an epitaxial surface attached to a thermally conductive submount by a thermally conductive...
US20170073385 Peptide Compounds and Methods of Production and Use Thereof  
Peptide compounds based on the CAP37 protein are disclosed, along with methods for treating various infections, wounds, and conditions, and methods of promoting healing and acceptance of grafts,...
9595428 Cellular probe device, system and analysis method  
A sampling probe, system and analysis method is disclosed. The sampling probe includes a tube having at least a first bore, a second bore, a first end, and a tapered second end; a first capillary...
US20170066800 Substrates and Inhibitors of Antiplasmin Cleaving Enzyme and Fibroblast Activation Protein and Methods of Use  
The presently disclosed inventive concept(s) include inhibitors of antiplasmin cleaving enzyme (APCE) and fibroblast activation protein alpha (FAP) which can be used in various therapies related...
9550144 Treatment of natural gas to remove contaminants  
A method of treating natural gas to remove contaminants is described. An input natural gas is mixed with water causing formation of CO2 hydrates and CH4 hydrates. A natural gas having a reduced...
US20170014510 Singlet Oxygen-Labile Linkers and Methods of Production and Use Thereof  
Activatable compositions that include at least one functional moiety and at least one cleavable linker directly or indirectly linked to the at least one functional moiety are disclosed. The at...
US20170014365 Compositions Containing Very Long Chain Saturated Fatty Acids and Methods of Use  
A fatty acid composition comprising at least one purified very long chain saturated fatty acid (VLC-SFA) having a chain length in a range of from about 28 carbons to about 40 carbons which is...
US20170014181 ESTIMATION OF LESION SIZE  
A method, consisting of ablating tissue for a time period, measuring a contact force applied during the time period, and measuring a power used during the time period. The method further includes...
US20170007589 Compositions For Treating Retinal Degeneration And Methods of Production and Use Thereof  
Compositions for use in methods of treating and/or inhibiting a pathologic ocular condition, as well as methods of producing and using same, are disclosed.
9540337 Gamma-glutamyl transpeptidase inhibitors and methods of use  
Compositions that are effective in inhibiting gamma-glutamyl transpeptidase are disclosed. Methods of producing and using these compositions are also disclosed.
9527884 Substrates and inhibitors of antiplasmin cleaving enzyme and fibroblast activation protein and methods of use  
The presently disclosed and claimed inventive concepts include inhibitors of antiplasmin cleaving enzyme (APCE) and fibroblast activation protein alpha (FAP) which can be used in various therapies...
9504745 Compositions and methods for cancer treatment using targeted carbon nanotubes  
Compositions for detecting and/or destroying cancer tumors and/or cancer cells via photodynamic therapy are disclosed, as well as methods of use thereof. The compositions comprise a linking...
US20160340302 ETHOXYLATED SURFACTANTS  
The present invention provides sulfur- or selenium-containing compounds comprising hydrophobic moieties and ethoxylated ester or ethoxylated amide moieties such that the compounds have surfactant...
US20160332194 KINETICALLY CONTROLLED SOL-GEL DOPING METHOD  
A new kinetically-controlled sol-gel doping method in which a dopant is applied to a sol-gel material during the transition (gelation) phase, rather than before or after the transition phase to an...
US20160317617 Peptide Compounds and Methods of Production and Use Thereof  
Peptide compounds based on the CAP37 protein are disclosed, along with methods for treating various infections, wounds, and conditions, and methods of promoting healing and acceptance of grafts,...
US20160315578 Thermophotovoltaic Materials, Methods of Deposition, and Devices  
Novel materials, material deposition methods, and devices used to generate electrical power from thermal radiators based on thermophotovoltatic (TPV) operating principles using group IV-VI alloys...
US20160289278 GENES OF AN OTITIS MEDIA ISOLATE OF NONTYPEABLE HEAMOPHILUS INFLUENZAE  
The invention relates to the polynucleotide sequence of a nontypeable strain of Haemophilus influenza (NTHi) and polypeptides encoded by the polynucleotides and uses thereof. The invention also...
US20160280743 BACTERIAL MUTANTS AND METHODS OF USE  
Mutants of Gram-negative bacteria having outer membranes comprising modified FhuA nanopores absent an N-terminal plug domain are disclosed. The modified FhuA nanopores confer the outer membrane...
9453940 System and method for tornado prediction and detection  
The presently disclosed inventive concepts are directed, in at least one non-limiting embodiment, to a computer system and method for issuing a tornado-indicative notification, such as a warning....