Patents and Patent Applications from University of North Texas Health Science Center


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US20170283629 METAL-BASED INK FOR ADDITIVE MANUFACTURING PROCESS  
The present invention includes an ink and method of applying the ink on a surface, wherein the ink comprises metal particles, an organic stabilizer, and a solvent, and methods of making electronic...
9761660 Manufacturable spin and spin-polaron interconnects  
Manufacturable spin and spin-polaron interconnects are disclosed that do not exhibit the same increase in resistivity shown by Cu interconnects associated with decreasing linewidth. These...
US20170240926 METHODS FOR PRENYLATION OF PEPTIDES AND THEIR USE IN OVER-PRODUCTION OF FARNESENE AND GERANYLGERANYL TERPENES  
Methods for concentrating biofuel precursors, including terpenes such as farnesyl and geranylgeranyl derivatives, are based on the prenylation of peptides in living organisms, such as plant or...
US20170232155 THERMO-MECHANICAL PROCESSING OF HIGH ENTROPY ALLOYS FOR BIOMEDICAL APPLICATIONS  
The present invention includes an apparatus and method of making the apparatus that biomedical apparatus comprises a device adapted for use in a biomedical application that comprises a high...
US20170209853 ALUMINUM BASED METALLIC GLASS POWDER FOR EFFICIENT DEGRADATION OF AZO DYE AND OTHER TOXIC ORGANIC CHEMICALS  
The present invention provides amorphous bi-functional catalytic aluminum metallic glass particles having an aluminum metallic glass core and 2 or more transition metals disposed on the surface of...
US20170165200 COMPOSITION OF LIPID-BASED NANOPARTICLES FOR SMALL MOLECULES AND MACROMOLECULES  
Described herein are nanoparticles comprising a mixture of a steroid, a phospholipid composition, an α-tocopheryl compound, and a therapeutic agent wherein the α-tocopheryl compound is presented...
US20170151350 PHOSPHORESCENT NANOPARTICLES AND THEIR USES IN BIOSENSING AND BIOIMAGING  
Size-tunable phosphorescent particles may be formed through self-assembly of biocompatible linear polymers, such as chitosan and other linear polymers, that bear positive surface charges, through...
US20170112775 SITU SELF-ASSEMBLING PRO-NANOPARTICLE COMPOSITIONS AND METHODS OF PREPARATION AND USE THEREOF  
Pharmaceutical composition comprising a pharmaceutically acceptable oil phase, a surfactant, and a therapeutic agent are provided herein, wherein the composition is in the form of a...
9624600 Direct graphene growth on metal oxides by molecular epitaxy  
Direct growth of graphene on Co3O4(111) at 1000 K was achieved by molecular beam epitaxy from a graphite source. Auger spectroscopy shows a characteristic sp2 carbon lineshape, at average carbon...
9612245 Multiple-pulse pumping for enhanced fluorescence detection and molecular imaging in cells and tissue  
The present invention includes a method and system for enhancing the signal-to-noise ratio in emission detection comprising: selecting a probe capable of at least one of fluorescence,...
US20170065721 SYNTHESIS AND USE OF THERAPEUTIC METAL ION CONTAINING POLYMERIC PARTICLES  
Therapeutic particles contain metal ions and are characterized by the use of unique ligand sets capable of making the metal ion complex soluble in biological media to induce selective toxicity in...
9574263 Controlled deposition of metal and metal cluster ions by surface field patterning in soft-landing devices  
A soft-landing (SL) instrument for depositing ions onto substrates using a laser ablation source is described herein. The instrument of the instant invention is designed with a custom drift tube...
9564579 Graphene magnetic tunnel junction spin filters and methods of making  
A Tunnel Magnetic Junction of high magnetoresistance is prepared at temperatures and pressure consistent with Si CMOS fabrication and operation. A first metal layer of cobalt or nickel is grown on...
9555011 Formulation of active agent loaded activated PLGA nanoparticles for targeted cancer nano-therapeutics  
The present invention includes compositions and methods of making an activated polymeric nanoparticle for targeted drug delivery that includes a biocompatible polymer and an amphiphilic...
US20170000748 METHOD FOR ENHANCING AMIDOHYDROLASE ACTIVITY OF FATTY ACID AMIDE HYDROLASE  
A method for enhancing amidohydrolase activity of Fatty Acid Amide Hydrolase (FAAH) is disclosed. The method comprising administering a phenoxyacyl-ethanolamide that causes the enhanced activity....
9533281 Porositization process of carbon or carbonaceous materials  
Porositized/activated carbon processed from carbon or carbonaceous raw materials. The porositization process comprises: (1) loading porositizing agents; (2) thermal treatment; and (3) porous...
9523925 Single reflective optical element for interference lithography  
A single reflective optical element is constructed for use in interference lithography. The single reflective optical element is generally made up of at least two, and preferably four, polished...
9506078 Engineering lipids in vegetative tissues of plants  
The present invention discloses gene targets and methods for the genetic control of lipid accumulation in vegetative (non-seed) portions of plants. Enhanced lipid, e.g. triacylglycerol (TAG),...
9485345 911 services and vital sign measurement utilizing mobile phone sensors and applications  
Improved methods for utilizing 911 services, for implementing 911 dispatch protocols, and for measuring vital signs of a human, all by accessing mobile phone sensors and applications, are...
9474271 Method for enhancing amidohydrolase activity of fatty acid amide hydrolase  
A method for enhancing amidohydrolase activity of Fatty Acid Amide Hydrolase (FAAH) is disclosed. The method comprising administering a phenoxyacylethanolamide that causes the enhanced activity....
US20160291036 PERSONALIZED MEDICINE APPROACH FOR TREATING COGNITIVE LOSS  
The present invention includes methods for selecting a therapy for improved cognition as well as prevention of cognitive loss/dysfunction using one or more endophenotypes comprising: obtaining a...
US20160278924 LASER-ASSISTED MACHINING (LAM) OF HARD TISSUES AND BONES  
An apparatus and method for laser-assisted machining (LAM) of bone without raising the temperature of the surrounding bone is discussed. The method of LAM of bone involves determining a target...
9453223 Piggy back delivery of nucleic acids into organisms  
The present invention includes nucleic acid hybrid molecules capable of entering cells comprising at least one vivo-morpholino oligonucleotide (vivo-MO) comprising a guanidine-rich head conjugated...
D766598 Plaid fabric  
9396135 Method and apparatus for improving computer cache performance and for protecting memory systems against some side channel attacks  
A physical cache memory that is divided into one or more virtual segments using multiple circuits to decode addresses is provided. An address mapping and an address decoder is selected for each...
9388450 FRET based multiplex probes  
The present invention includes compositions and methods for fluorescence-based multiplex probe to simultaneously detect one or more enzymatic activities comprising: a first enzymatic target having...
9387041 Laser-assisted machining (LAM) of hard tissues and bones  
An apparatus and method for laser-assisted machining (LAM) of bone without raising the temperature of the surrounding bone is discussed. The method of LAM of bone involves determining a target...
9379232 Magneto-electric voltage controlled spin transistors  
The invention relates to a magneto-electric spin-FET including a gate film of chromia and a thin film of a conductive channel material which may be graphene, InP, GaAs, GaSb, PbS, MoS2, WS2,...
9376315 Polarized fluorescent nanospheres  
The present invention provides partially fluorescent nanoparticles and methods of making and using the partially fluorescent nanoparticle having a nanoparticle with a matrix and a fluorescent dye...
9366601 Wafer fabrication monitoring/control system and method  
A wafer fabrication monitoring/control system and method is disclosed. The invention utilizes Multiple Internal Reflection Infrared Detection (MIR-IR) to provide a highly sensitive (sub-10 nm,...
US20160154010 BLOOD-BASED SCREEN FOR DETECTING NEUROLOGICAL DISEASES IN PRIMARY CARE SETTINGS  
The present invention includes methods and kits for the diagnosing a neurological disease within primary care settings comprising: obtaining a blood test sample from a subject, measuring IL-7 and...
9331198 Controlled epitaxial boron nitride growth for graphene based transistors  
We have demonstrated controlled growth of epitaxial h-BN on a metal substrate using atomic layer deposition. This permits the fabrication of devices such as vertical graphene transistors, where...
9314532 Drug delivery vehicle  
The present disclosure provides targeted drug delivery vehicle compositions comprising a drug composition and targeted poly-amino-acid subunits, methods of manufacture, and methods of treatment...
US20160093491 LARGE SCALE AND THICKNESS-MODULATED MoS2 NANOSHEETS  
The invention is for fabricating large-area, thickness-modulated MoS2, varying from single to few layer MoS2 films on various substrates using a combination of magnetron sputtering followed by...
9297021 MtNIP regulated plants with significantly increased size and biomass  
A composition and method for producing plants with increased biomass and growth characteristics, and plants which flower early relative to wild-type plants. The MtNIP gene is over-expressed in...
9228145 Anti-fretting wear coating for substrates  
A method and chemical composition and material structure for improving fretting wear in substrates, particularly carbon-carbon composite (CCC). The invention relates to trilayer coatings,...
9218947 Nanomanipulation coupled nanospray mass spectrometry (NMS)  
A coupled nanomanipulation and nanospray mass spectrometry (NMS) system for single cell, single organelle, and ultra-trace molecular analysis is disclosed herein. The system primarily comprises a...
US20150359218 METHOD FOR ENHANCING AMIDOHYDROLASE ACTIVITY OF FATTY ACID AMIDE HYDROLASE  
A method for enhancing amidohydrolase activity of Fatty Acid Amide Hydrolase (FAAH) is disclosed. The method comprising administering a phenoxyacylethanolamide that causes the enhanced activity....
US20150354100 CARBON FIBERS DERIVED FROM POLY-(CAFFEYL ALCOHOL) (PCFA)  
Poly-(caffeyl alcohol) (PCFA), also known as C-lignin, is a promising new source of both carbon fibers and pure carbon. PCFA can be used to produce carbon fibers by direct electrospinning, without...
US20150351647 EFFECTIVE CPR PROCEDURE WITH REAL TIME EVALUATION AND FEEDBACK USING SMARTPHONES  
A method for performing CPR, comprising activating an application on one or more mobile phones having one or more sensors, placing one or more mobile phones on the finger of a subject to collect...
US20150343085 Direct Utilization of Plasma Proteins for the In Vivo Assembly of Protein-Drug/Imaging Agent Conjugates, Nanocarriers and Coatings for Biomaterials  
The present invention includes compositions and methods for making and using a drug conjugated to a peptide or protein that binds specifically to a ligand in vivo, wherein the conjugate binds to...
US20150343069 DRUG DELIVERY VEHICLE  
The invention provide herein provides for a targeted drug delivery vehicle compositions, methods of manufacture, and methods of treatment for therapeutic applications.
9192598 Prevention of bacterial growth and biofilm formation by ligands that act on cannabinoidergic systems  
A group of antimicrobial compounds shows effectiveness for preventing bacterial growth and bio film formation. In particular, the compounds are effective for preventing the growth of gram-positive...
US20150329870 Methods for Elevating Fat/Oil Content in Plants  
In some embodiments, the present invention provides a method of elevating lipid content in vegetative (non-seed) plant or algal cells, plant tissues, or whole plants by genetically modifying the...
US20150299238 SYNTHESIS AND USE OF PRODRUG COMPLEXES OF COBALT IN POLYMER THERAPEUTICS  
Degradable compounds that can be controlled to degrade and can be used for delivery of a cargo component. Cobalt (III) complexes have been exploited as vehicles for molecular complexes. This...
9138411 Curcumin-ER, a liposomal-PLGA sustained release nanocurcumin for minimizing QT prolongation for cancer therapy  
The present invention includes compositions and methods of making a nanoparticle composition comprising a polymeric core comprising one or more polymers and one or more active agents, and at least...
US20150258026 CURCUMIN-ER, A LIPOSOMAL-PLGA SUSTAINED RELEASE NANOCURCUMIN FOR MINIMIZING QT PROLONGATION FOR CANCER THERAPY  
The present invention includes compositions and methods of making a nanoparticle composition comprising a polymeric core comprising one or more polymers and one or more active agents, and at least...
9125949 Direct utilization of plasma proteins for the in vivo assembly of protein-drug/imaging agent conjugates, nanocarriers and coatings for biomaterials  
The present invention includes compositions and methods for making and using a drug conjugated to a peptide or protein that binds specifically to a ligand in vivo, wherein the conjugate binds to...
US20150247146 Piggy Back Delivery of Nucleic Acids Into Organisms  
The present invention includes nucleic acid hybrid molecules capable of entering cells comprising at least one vivo-morpholino oligonucleotide (vivo-MO) comprising a guanidine-rich head conjugated...
US20150246083 GENETICALLY MODIFIED PROBIOTIC FOR THE TREATMENT OF PHENYLKETONURIA (PKU) DISEASE  
A GMP adapted to provide the PAL gene for the treatment of PKU when administered orally. The GMP of the present invention may include a probiotic, a PAL gene to be expressed using the probiotic,...
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