Patents and Patent Applications from University of North Carolina


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9843189 Grid tied system controller including logic coupled to a photovoltaic station and an energy storage system  
A battery energy storage system control system, including: logic coupled to a photovoltaic station and an energy storage system and executing a photovoltaic station capacity firming algorithm...
9841367 Methods and devices for optical sorting of microspheres based on their resonant optical properties  
Microspheres are sorted by resonant light pressure effects. An evanescent optical field is generated when light is confined within the interior of an optical element such as a surface waveguide, a...
US20170345398 MINIMAL-LATENCY TRACKING AND DISPLAY FOR MATCHING REAL AND VIRTUAL WORLDS IN HEAD-WORN DISPLAYS  
Methods, systems, and computer readable media for minimal-latency tracking and display for matching real and virtual worlds in head-worn displays are disclosed. According to one aspect, a method...
9832705 Methods, systems, and computer readable media for topology management and geographic routing in mobile ad-hoc networks  
Methods, systems, and computer readable media for topology management and geographic routing in mobile ad-hoc networks are disclosed. One method for geographic routing in mobile ad-hoc networks...
9828588 Methods and compositions for producing active vitamin K-dependent proteins  
The present invention provides a stable cell line overexpressing a recombinant vitamin K-dependent (VKD) protein and both a recombinant vitamin K epoxide reductase (VKOR) and a recombinant vitamin...
US20170338659 SYSTEMS AND METHODS FOR DISPATCHING MAXIMUM AVAILABLE CAPACITY FOR PHOTOVOLTAIC POWER PLANTS  
Systems, apparatuses, and methods for dispatching maximum available capacity for photovoltaic (PV) power plants are described. For an embodiment, a PV panel assembly comprises a first PV panel...
US20170333548 METHODS AND COMPOSITIONS FOR RECOMBINANT DENGUE VIRUSES FOR VACCINE AND DIAGNOSTIC DEVELOPMENT  
The present invention provides compositions and methods of use comprising a chimeric dengue virus E glycoprotein comprising a dengue virus E glycoprotein backbone, which comprises amino acid...
US20170333347 METAL BISPHOSPHONATE NANOPARTICLES FOR ANTI-CANCER THERAPY AND IMAGING AND FOR TREATING BONE DISORDERS  
Metal-bisphosphonate nanoparticles are disclosed. Also disclosed are pharmaceutical compositions including the metal-bisphosphonate nanoparticles, methods of preparing the metal-bisphosphonate...
US20170332622 COMPOSITIONS AND METHODS FOR PRESERVATION AND STORAGE OF BIOLOGICAL MATERIALS  
In one aspect, solvent systems are described herein. In some embodiments, such a solvent system comprises a disaccharide component, choline halide or choline acetate, and water. The water is...
9824166 Methods, systems, and computer readable media for utilizing parallel adaptive rectangular decomposition (ARD) to perform acoustic simulations  
Methods, systems, and computer readable media for utilizing parallel adaptive rectangular decomposition (ARD) to perform acoustic simulations are disclosed herein. According to one method, the...
9821050 Chimeric dengue virus E glycoproteins comprising mutant domain I and domain II hinge regions  
The present invention provides compositions and methods of use comprising a chimeric dengue virus E glycoprotein comprising a dengue virus E glycoprotein backbone, which comprises amino acid...
US20170331251 Light-Effect Transistor (LET)  
Example photoconductive devices and example methods for using photoconductive devices are described. An example method may include providing a photoconductive device having a...
US20170329037 MOBILE AND FREE-FORM X-RAY IMAGING SYSTEMS AND METHODS  
A three-dimensional (3D) x-ray tomographic imaging system includes an x-ray source fixedly attached to a first unmanned vehicle, which can be aerial or otherwise configured for locomotion, and an...
US20170327538 Peptide Inhibitors of Sodium Channels  
The present invention relates to the ability of specialized non-naturally occurring peptides to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates...
9818594 Integrated sample processing for electrospray ionization devices  
Methods, systems and devices that generate differential axial transport in a fluidic device having at least one fluidic sample separation flow channel and at least one ESI emitter in communication...
US20170324757 MULTIPLE DETECTOR METHODS AND SYSTEMS FOR DEFEATING LOW AND SLOW APPLICATION DDOS ATTACKS  
Methods and systems for detecting and defeating a low and slow application DDoS attack, comprising: computing the Entropy of a plurality of detectors, at least in part selected from a group Geo...
US20170322180 PRESSURE DRIVEN MICROFLUIDIC INJECTION FOR CHEMICAL SEPARATIONS  
Methods that allow independently applied pressures to a BGE reservoir and a sample reservoir for pressure-driven injection that can inject a discrete sample plug into a separation channel that...
9812527 Growth of semiconductors on hetero-substrates using graphene as an interfacial layer  
Graphene is used as an interfacial layer to grow Si and other semiconductors or crystalline materials including two-dimensional Si and other structures on any foreign substrate that can withstand...
9810825 Curved volume phase holographic (VPH) diffraction grating with tilted fringes and spectrographs using same  
The subject matter described herein includes a curved VPH grating with tilted fringes and spectrographs, both retroreflective and transmissive, that use such gratings. A VPH grating according to...
9808461 Protection of renal tissues from ischemia through inhibition of the proliferative kinases CDK4 and CDK6  
The presently disclosed subject matter relates to methods and compositions for protecting cells and or tissues from damage due to ischemia. In particular, the presently disclosed subject matter...
9802967 Polymer coated particles and methods thereof  
Embodiments of the presently-disclosed subject matter include a composition that comprises a particle, a plurality of surface functional groups on a surface of the particle, and a plurality of...
US20170309840 HIGH EFFICIENCY DYE SENSITIZED PHOTOELECTROSYNTHESIS CELLS  
Electrodes useful in dye sensitized photoelectrosynthesis cells provide a coreshell nanoparticle having a chromophore and a catalyst, or a chromophore-catalyst assembly, linked to the shell...
US20170309204 MODULAR STAGED REALITY SIMULATOR  
This invention is directed to a modular staged simulator and a process of simulating medical trauma and maladies for the purpose of training or certifying individuals including medical...
US20170307782 GRADIENT-OPTICAL-INDEX POROUS (GRIP) COATINGS BY LAYER CO-DEPOSITION AND SACRIFICIAL MATERIAL REMOVAL  
The present invention provides a specific gradient-optical-index porous (GRIP) layer coating on inorganic optical substrate surfaces, and the fabrication method used to create the GRIP layer...
9797136 High performance architectural precast concrete wall system  
A construction panel comprising a rigid insulation layer having an interior surface and an exterior surface, an outer concrete wythe secured to the exterior surface of the insulation layer, an...
9796987 Polypurine tract modified retroviral vectors  
An integration-defective retroviral vector transfer cassette lacking a functional polypurine tract (PPT) is provided. Also provided are isolated nucleic acids that include a heterologous...
9796985 Compositions and method for modulating the sensitivity of plants to cytokinin  
The present invention includes an expression cassette containing a polynucleotide encoding a polypeptide; and a host cell, transgenic plant (e.g., a dicot or monocot), transformed seed, and...
9796768 Peptide inhibitors of sodium channels  
The present invention relates to the ability of specialized non-naturally occurring peptides to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates...
9795606 Pyrrolopyrimidine compounds for the treatment of cancer  
Compounds of Formula I: wherein: one of X and X′ is N and the other of X and X′ is C, are described, along with compositions containing the same and methods of use thereof in the treatment of cancer.
US20170301527 SOLID PHASE EXTRACTION WITH CAPILLARY ELECTROPHORESIS  
Methods, systems and devices that provide fluid devices with at least one SPE bed adjacent (upstream of) a separation channel which may be in communication with an inlet of a Mass Spectrometer....
US20170298414 MOLECULAR DIAGNOSIS AND TYPING OF LUNG CANCER VARIANTS  
Compositions and methods useful in determining the major morphological types of lung cancer are provided. The methods include detecting expression of at least one gene or biomarker in a sample....
9792715 Methods, systems, and computer readable media for utilizing synthetic animatronics  
Methods, systems, and computer readable media for utilizing synthetic animatronics are disclosed. According to one aspect, a method for synthetic animatronics includes providing a display surface...
9791618 Waveguides incorporating novel metamaterials and associated methods of manufacture  
A hollow-core waveguide structure for guiding an electromagnetic signal, comprising: a core material comprising a predetermined refractive index; and a cladding structure disposed about the core...
9791265 Methods of determining the shape of a sessile drop  
In one aspect, methods of determining the shape of a sessile drop are described herein. In some embodiments, a method described herein comprises measuring a first shape parameter of a sessile drop...
9782769 Light beam guided liquid delivery device  
A light beam guided liquid delivery device, including: a liquid delivery device; a light beam generator; and a bracket coupling the light beam generator to the liquid delivery device such that a...
9782136 Intraoral tomosynthesis systems, methods, and computer readable media for dental imaging  
Intraoral tomosynthesis systems, methods, and computer readable media for dental imaging can include an x-ray source containing multiple focal spots spatially distributed on one or multiple anodes...
US20170287353 ALCOHOL AND DRUG INTERVENTION SYSTEM AND METHOD  
An alcohol and drug intervention system and method, comprising: a server component; and a mobile application component wirelessly coupled to the server component; wherein the server component and...
US20170274024 AAV Vectors Targeted to Oligodendrocytes  
The invention relates to chimeric AAV capsids targeted to oligodendrocytes, virus vectors comprising the same, and methods of using the vectors to target oligodendrocytes.
9771330 Pyrimidine compounds for the treatment of cancer  
Compounds of Formula I or II: are described, along with pharmaceutical compositions containing the same and methods of using such compounds for the treatment of cancer.
US20170271912 DISPATCHABLE PHOTOVOLTAIC PANEL WITH FULLY INTEGRATED ENERGY STORAGE AND GRID INTERACTIVE POWER CONVERSION  
A dispatchable photovoltaic (PV) panel product that includes multiple types of voltage sources is described. The product can include a PV panel that includes PV cells, a battery, and a panel level...
US20170271139 MASS SPECTROMETRY SYSTEMS WITH CONVECTIVE FLOW OF BUFFER GAS FOR ENHANCED SIGNALS AND RELATED METHODS  
Mass spectrometry systems include an ionizer, mass analyzer and the detector, with a high pressure chamber holding the mass analyzer and a separate chamber holding the detector to allow for...
US20170266317 Synthetically Functionalized Living Cells for Targeted Drug Delivery  
Uniform, functional polymer patches can be attached to a fraction of the surface area of living individual cells. These surface-modified cells can cross the blood-brain barrier while remaining...
US20170266188 Methods For the Treatment of Cancer  
The invention provides combinations comprising a MERTK inhibitor, or a pharmaceutically acceptable salt thereof, and an EGFR inhibitor and methods of use thereof, including methods of treating...
9765291 Array of micromolded structures for sorting adherent cells  
An apparatus for collecting or culturing cells or cell colonies includes: a common substrate formed from a flexible resilient polymeric material and having a plurality of wells formed therein; and...
US20170263432 MINIATURE CHARGED PARTICLE TRAP WITH ELONGATED TRAPPING REGION FOR MASS SPECTROMETRY  
A miniature electrode apparatus is disclosed for trapping charged particles, the apparatus including, along a longitudinal direction: a first end cap electrode; a central electrode having an...
9757431 Methods and compositions for the induction of hypothermia  
Provided herein are methods for the induction of hypothermia and the treatment of clinical insults in a subject through the administration of a regulated hypothermic multidrug combination. The...
9755273 Ion conducting fluoropolymer carbonates for alkali metal ion batteries  
Liquid or solid electrolyte compositions are described that comprise a homogeneous solvent system and an alkali metal salt dissolved in said solvent system. The solvent system may comprise a...
9752983 Optical density monitor and comparator systems and methods  
The present disclosure relates generally to systems and methods for determining the absorption coefficient and the optical density of a fluid as they relate to the wavelength of incident...
9750836 Systems and methods for performing the bacterial disinfection of a fluid using point radiation source  
A system for disinfecting a fluid, including: a flow cell including one or more inlet ports and one or more outlet ports, wherein the flow cell is configured to communicate a fluid containing a...
9750770 Method of treating pancreatic and liver conditions by endoscopic-mediated (or laparoscopic-mediated) transplantation of stem cells into/onto bile duct walls of particular regions of the biliary tree  
A method of repairing diseased or dysfunctional pancreas or liver is provided. The method involves preparation of a suspension of stem cells and/or progenitor cells such as biliary tree stem...