Patents and Patent Applications from University of Nebraska


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US20190330147 PYRROLOMYCINS AND METHODS OF USING THE SAME  
Provided herein are pyrrolomycin derivatives, which can be used to modulate Mcl-1, inhibit proliferation of bacteria and pathogens, as well as to treat infectious diseases and cancers.
US20190328693 CREATINE ORAL SUPPLEMENTATION USING CREATINE HYDROCHLORIDE SALT  
The present invention is directed to an oral supplement including creatine hydrochloride, which has an aqueous solubility that is at least 15 times greater than creatine monohydrate, where the...
10456063 System and Method for Monitoring Pleural Fluid  
The disclosure is directed to intrapleural air leak detection and monitoring. According to various embodiments of the disclosure, an air leak may be detected utilizing at least one sensor to...
US20190326065 MOLECULAR DOPING ENABLED SCALABLE BLADING OF EFFICIENT HOLE TRANSPORT LAYER-FREE PEROVSKITE SOLAR CELLS  
A method of forming a photoactive device includes steps of: forming a photoactive layer, the photoactive layer comprising a perovskite material and a dopant; wherein the photoactive device...
US20190322680 Dimers of Covalent NFKB Inhibitors  
Provided herein are compounds and methods for modulating the NFKB pathway. More particularly, provided are inhibitors of the NFKB pathway and the uses of such inhibitors in regulating diseases and...
US20190315629 Ozone-Mediated Synthesis of Nanostructures  
A method of producing ceria nanocrystals is provided. The method includes providing a gas that includes ozone to a solution that includes a cerium salt, and obtaining ceria nanocrystals from the...
US20190314340 ANTIMICROBIAL COMPOSITIONS CONTAINING A SYNERGISTIC COMBINATION OF ACTIVATED CREATININE AND AN IMIDAZOLE ANTIFUNGAL AGENT  
An antimicrobial composition containing a synergistic combination of an imidazole antifungal agent and activated creatinine is provided, wherein the imidazole antifungal agent represents in the...
10433847 Platform device and method of use to assist in anastomosis formation  
There is described a platform device for use in forming an anastomosis and maintaining a desired curvature of a lumen in a desired shape during an anastomosis assistance period. The platform is...
US20190290297 ON-BOARD TOOL TRACKING SYSTEM AND METHODS OF COMPUTER ASSISTED SURGERY  
A number of improvements are provided relating to computer aided surgery utilizing an on tool tracking system. The various improvements relate generally to both the methods used during computer...
US20190282687 DEVELOPMENT OF A PREVENTIVE INFLUENZA D VIRUS VACCINE  
The present disclosure provides a DNA vaccine or immunogenic composition expressing consensus hemagglutinin-esterase-fusion (HEF) protein (FluD-Vax) and a protein-based vaccine utilizing the HEF...
10414725 Pyrrolomycins and methods of using the same  
Provided herein are pyrrolomycin derivatives, which can be used to modulate Mcl-1, inhibit proliferation of bacteria and pathogens, as well as to treat infectious diseases and cancers.
10398811 Medical irrigation system  
Medical wound irrigation systems are described that may be used in environments such as hospitals and first aid stations, and for military applications, e.g., for medics and along transport routes...
US20190261866 DEVICES AND METHODS FOR DETECTING AND MEASURING SYMPATHETIC VASOMOTION  
Sympathetic vasomotor identification and quantification systems that provide ways to assess therapies, diseases, and conditions which affect sympathetic innervation and function are described....
US20190247354 CREATINE ESTER ANTI-INFLAMMATORY COMPOUNDS AND FORMULATIONS  
The present invention provides a creatine ester anti-inflammatory compound which may be received by animals and then metabolized into a biologically active form of creatine. The biologically...
10376323 Multifunctional operational component for robotic devices  
The various embodiments disclosed herein relate to modular medical devices, including various devices with detachable modular components and various devices with pivotally attached modular...
10376322 Robotic device with compact joint design and related systems and methods  
The embodiments disclosed herein relate to various robotic and/or in vivo medical devices having compact joint configurations. Other embodiments relate to various medical device components,...
US20190240541 USER-PACED EXERCISE EQUIPMENT  
Disclosed herein are examples of user-paced exercise equipment, as well as related circuitry, methods, and computer-readable media. For example, disclosed herein is a user-paced treadmill,...
10363282 Analogs of C5a and methods of using same  
Materials and methods for treating an infection or disease, activating an immune cell at a site of infection or disease, and for directly killing microorganisms, using response-selective...
10361292 Magneto-electric logic devices using semiconductor channel with large spin-orbit coupling  
Antiferromagnetic magneto-electric spin-orbit read (AFSOR) logic devices are presented. The devices include a voltage-controlled magnetoelectric (ME) layer that switches polarization in response...
10357601 Method and apparatus for fibrin sheath disruption  
A hemodialysis catheter is disclosed for deploying in an artery or vein, comprising various means for disrupting, mechanically and/or chemo-mechanically, a fibrous sheath forming naturally outside...
US20190216552 Single-Manipulator Robotic Device With Compact Joint Design and Related Systems and Methods  
Disclosed herein are various robotic surgical devices and systems that include first and second elongate bodies, first and second driveshafts disposed through the second elongate body, and an...
10350000 Methods, systems, and devices relating to surgical end effectors  
The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices, and more specifically...
US20190209732 Nanofiber Structures and Methods of Use Thereof  
Coated and expanded, nanofiber structures are provided and methods of use thereof.
10344340 Plants with useful traits and related methods  
The present invention provides methods for obtaining plants that exhibit useful traits by transient suppression of the MSH1 gene of the plants. Methods for identifying genetic loci that provide...
10342771 Creatine oral supplementation using creatine hydrochloride salt  
The present invention is directed to an oral supplement including creatine hydrochloride, which has an aqueous solubility that is at least 15 times greater than creatine monohydrate, where the...
10342561 Quick-release end effectors and related systems and methods  
The various embodiments disclosed herein relate to arms or forearms of medical devices that are configured to couple with quick-release end effectors, quick-release end effectors for use with such...
US20190201133 Single Site Robotic Device and Related Systems and Methods  
Disclosed herein are various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices. Also disclosed are various medical devices for in...
10335024 Medical inflation, attachment and delivery devices and related methods  
The various embodiments disclosed herein relate to procedural space maintenance devices, medical device positioning devices, and devices that provide both procedural space maintenance and device...
US20190192741 Ring and Tubular Structures and Methods of Synthesis and Use Thereof  
Nanofiber structures are provided along with methods of production and methods of use.
US20190192013 Apparatus for Assessing User Frailty  
An apparatus for assessing user frailty is disclosed. In embodiments, the apparatus includes a housing that defines (or is defined by) a body and a handle coupled to the body. The apparatus...
10333439 Methods of estimating a position of a rotor in a motor under transient and systems thereof  
At least one example embodiment discloses a method of estimating a position of a rotor in a motor. The method includes obtaining a current regulation quality index based on a current command and a...
10332661 Rare earth-free permanent magnetic material  
The invention provides rare earth-free permanent magnetic materials and methods of making them. The materials can be used to produce magnetic structures for use in a wide variety of commercial...
10307199 Robotic surgical devices and related methods  
The present invention relates to robotic surgical devices. More specifically, the present invention relates to robotic surgical devices that can be inserted into a patient's body and can be...
US20190164699 PEROVSKITE SURFACE DEFECT PASSIVATION USING ZWITTERIONIC AMINO ACIDS  
Semiconductor devices including a cathode layer, an anode layer, an active layer disposed between the cathode layer and the anode layer, wherein the active layer includes a perovskite layer, and a...
US20190162865 MONOLITHIC INTEGRATION OF HYBRID PEROVSKITE SINGLE CRYSTALS WITH SILICON FOR HIGHLY SENSITIVE X-RAY DETECTORS  
Perovskite single crystal X-ray radiation detector devices including an X-ray wavelength-responsive active layer including an organolead trihalide perovskite single crystal, a substrate layer...
US20190153539 EVALUATION OF MANTLE CELL LYMPHOMA AND METHODS RELATED THERETO  
The present invention provides methods of determining a survival predictor score of a subject having mantle cell lymphoma (MCL). The present invention also provides methods of predicting the...
US20190140181 SENSITIVE X-RAY AND GAMMA-RAY DETECTORS INCLUDING PEROVSKITE SINGLE CRYSTALS  
Perovskite single crystal X-ray and gamma-ray radiation detector devices include an X-ray and gamma-ray wavelength responsive active layer including a perovskite single crystal. The perovskite...
US20190117735 BIOMARKERS FOR MONITORING IMMUNE TRANSFORMATION  
The present invention provides novel biomarkers for regulatory T cells (Treg) function and Parkinson's disease.
US20190098880 BIOMARKERS FOR RESISTANCE TO PORCINE CIRCOVIRUS 2 ASSOCIATED DISEASE  
The present disclosure provides compositions and methods for increasing resistance to PCV2 infection in pigs. The increased resistance may be the result of siRNA or genetic modification through...
US20190097144 INSULATING TUNNELING CONTACT FOR EFFICIENT AND STABLE PEROVSKITE SOLAR CELLS  
Perovskite-based photoactive devices, such as solar cells, include an insulating tunneling layer inserted between the perovskite photoactive material and the electron collection layer to reduce...
US20190090959 ON-BOARD TOOL TRACKING SYSTEM AND METHODS OF COMPUTER ASSISTED SURGERY  
A number of improvements are provided relating to computer aided surgery utilizing an on tool tracking system. The various improvements relate generally to both the methods used during computer...
US20190083408 CONTROLLED-RELEASE PEPTIDE COMPOSITIONS AND USES THEREOF  
Controlled-release formulations of carboxy-terminal C5a analogs (such as sustained-release formulations of the analogs), and their use in methods for treating and preventing an infection or a...
10233544 Growth of nitride films  
A gallium nitride thin film can be formed on a substrate at a low temperature (e.g., not higher than 600° C.) by applying a laser to resonantly excite molecules of a first precursor that contains...
US20190070370 SYSTEMS AND METHODS FOR VENTILATION THROUGH A BODY CAVITY  
A system and methods for the delivery of oxygen through a body cavity of a subject using oxygen microbubbles. Through circulation of oxygen microbubbles through the body cavity, oxygen and carbon...
10220002 Controlled-release peptide compositions and uses thereof  
Controlled-release formulations of carboxy-terminal C5a analogs (such as sustained-release formulations of the analogs), and their use in methods for treating and preventing an infection or a...
10219870 Single site robotic device and related systems and methods  
Disclosed herein are various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices. Also disclosed are various medical devices for in...
10219811 On-board tool tracking system and methods of computer assisted surgery  
A number of improvements are provided relating to computer aided surgery utilizing an on tool tracking system. The various improvements relate generally to both the methods used during computer...
10206897 Creatine ester anti-inflammatory compounds and formulations  
The present invention provides a creatine ester anti-inflammatory compound which may be received by animals and then metabolized into a biologically active form of creatine. The biologically...
US20190048052 ANTI-MICROBIAL PEPTIDES AND COATINGS  
Antimicrobial peptides and methods of use are provided.
US20190046234 Methods, Systems, and Devices for Surgical Access and Insertion  
The various embodiments herein relate to systems, devices, and/or methods relating to surgical procedures, and more specifically for accessing an insufflated cavity of a patient and/or positioning...