Patents and Patent Applications from University of Minnesota


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US20170353807 SYSTEMS AND METHODS FOR TREATING TINNITUS AND ENHANCING HEARING  
Systems and methods for treating hearing loss and/or tinnitus or enhancing hearing to sounds or sound features such as in a noisy environment are disclosed. An apparatus includes a hearing aid and...
US20170350248 CONTROL SIGNALS FOR FREE-PISTON ENGINES  
The subject matter of this specification can be embodied in, among other things, a method for operating a hydraulic free piston engine includes receiving, at an engine controller for a hydraulic...
US20170349267 FAULT-TOLERANT AIRCRAFT FLIGHT CONTROL USING A SUBSET OF AERODYNAMIC CONTROL SURFACES  
A method for controlling an unmanned aerial vehicle (UAV) is described. In one example, the method includes: detecting, by one or more processors of a controller within a UAV, whether flight...
US20170348659 Engine Fuel-Reforming Reactors, Systems, and Methods  
An engine system for internal combustion and reformation of a fuel includes an engine, and a reforming reactor. The engine comprising an intake manifold for receiving a first fuel and an exhaust...
9834823 Primers, assays and methods for detecting an E. coli subtype  
Disclosed are primers, probes, and single nucleotide polymorphisms (SNP) specific to a distinct subclones of the E. coli sequence type 131 (ST131). Also disclosed are methods and assay kits useful...
US20170345326 PROCESS FOR USING TEST ITEM RESPONSE TIMES TO IMPROVE MEASUREMENT OF COGNITIVE ABILITY  
A method includes providing user interfaces from a server to present questions to a plurality of test takers. For each question and each test taker, an elapsed time is recorded and the elapsed...
US20170343549 METHODS FOR DETECTING AND MONITORING COLORECTAL CANCER  
A method for detecting and/or measuring circulating TXA2 in a subject having or at risk of having colorectal cancer. Generally, the method includes obtaining a biological sample from the subject,...
US20170343356 RESOURCE-AWARE LARGE-SCALE COOPERATIVE 3D MAPPING USING MULTIPLE MOBILE DEVICES  
A method includes: receiving, with a computing platform, respective trajectory data and map data independently generated by each of a plurality of vision-aided inertial navigation devices (VINS...
US20170342107 MELANOCORTIN LIGANDS AND METHODS OF USE THEREOF  
Certain embodiments of the invention provide a compound of formula (I): R1—C(═O)—W—X—Y—Z—N(R2)2 (I) or a salt thereof, wherein R1, R2, W, X, Y and Z are as defined herein, as well as methods of...
9827295 Methods to treat mucopolysaccharide type I or deficiency in alpha-L-iduronidase using a recombinant adeno-associated virus encoding alpha-L-iduronidase  
A method to prevent, inhibit or treat one or more symptoms associated with a disease of the central nervous system by intrathecally, intracerebroventricularly or endovascularly administering a...
9827228 Opioid receptor modulators and use thereof  
Disclosed is an in vitro screening method for identifying an antagonist-to-agonist allosteric modifier of a mu-opioid receptor and an in vivo method for confirming that a test compound is such a...
US20170337983 FAST MAGNETOELECTRIC DEVICE BASED ON CURRENT-DRIVEN DOMAIN WALL PROPAGATION  
In some examples, an electronic device comprising an input ferroelectric (FE) capacitor, an output FE capacitor, and a channel positioned beneath the input FE capacitor and positioned beneath the...
US20170334950 SUBSTRATES FOR FLT3 KINASE AND USES THEREOF  
The invention provides kinase substrates and methods comprising their use.
US20170333547 PERTUSSIS VACCINES AND METHODS OF MAKING AND USING  
Bordetella pertussis iron receptor proteins or portions thereof (e.g., one or more extracellular domains), alone or spliced into B. pertussis scaffold proteins (e.g., fimbrial or flagellin), are...
US20170333417 SALTS AND COMPOSITIONS USEFUL FOR TREATING DISEASE  
The invention provides a combination or salt of lipoic acid and a compound of formula (I): The combinations and salts are useful for treating diabetes.
9823316 Magnetic biomedical sensors and sensing system for high-throughput biomolecule testing  
A magnetic biosensor can include a magnetic stack comprising a free layer, a fixed layer, and a nonmagnetic layer between the free layer and the fixed layer. At least one of the free layer or the...
US20170330660 IRON NITRIDE PERMANENT MAGNET AND TECHNIQUE FOR FORMING IRON NITRIDE PERMANENT MAGNET  
A bulk permanent magnetic material may include between about 5 volume percent and about 40 volume percent Fe16N2 phase domains, a plurality of nonmagnetic atoms or molecules forming domain wall...
US20170329954 ROBUST DEVICE AUTHENTICATION  
An apparatus includes a finite state machine and a physical structure capable of providing a response to a challenge, the physical structure such that before the physical structure is ever...
US20170328912 GLYCOPOLYMER CAPTURE MATRIX FOR USE WITH SURFACE-ENHANCED RAMAN SPECTROSCOPY DETECTION AND RELATED SYSTEMS AND METHODS  
A method of making a sensor includes subjecting a metal substrate to a solution having glycopolymer chains and attaching the glycopolymer chains to the metal substrate to form a...
US20170326181 Compositions and Methods for Transplantation of Colon Microbiota  
The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a...
9818231 Computer visualization of anatomical items  
A computer-implemented medical visualization method includes identifying a three-dimensional model of an anatomical item of a particular mammal; automatically identifying an open path in...
9815808 Recovery of monomer from polyurethane materials by depolymerization  
Methods for recovering monomers from polymers, such as polyurethanes (including thermoset polyurethanes) include heating the polymer to depolymerize the polymer and release the monomer. The...
US20170319627 Compositions and Methods for Transplantation of Colon Microbiota  
The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a...
US20170319326 ACTIVE MONITORING PRESSURE SENSITIVE VASCULAR GRAFT  
A vascular graft includes deformable sleeves that include an electrical component. The electrical component can be variable-resistance or piezoelectric, in embodiments, such that deformation of...
9812457 Ultra high density integrated composite capacitor  
Capacitors that can be formed fully on an integrated circuit (IC) chip are described in this disclosure. An IC chip includes a metal-oxide-silicone (MOS) capacitor formed from a MOS transistor...
US20170318397 ULTRASONIC HEARING SYSTEM AND RELATED METHODS  
A hearing system to activate an auditory system using cerebrospinal fluids includes at least one processor configured to receive an audio signal captured using a sound sensor (e.g., a microphone),...
US20170316135 VIRTUAL OSCILLATOR CONTROL  
Virtual oscillator control systems, devices, and techniques are provided. One example device includes a processor configured to implement a virtual oscillator circuit and output an oscillating...
US20170314044 ADENOVIRUS CONSTRUCTS AND METHODS  
This disclosure describes oncolytic adenovirus constructs and methods on using the constructs. Generally, the oncolytic constructs includes at least a partial deletion of E3, a heterologous...
US20170311875 3D SHOULDER MOTION MEASUREMENT DEVICE AND SCAPULAR ANGLE LOCATOR  
Examples of systems, devices, and methods as described in this disclosure include a shoulder motion measurement system comprising a mounting device comprising a receptacle configured to hold an...
9805624 Simulated, representative high-fidelity organosilicate tissue models  
A method of making a tissue model comprises determining one or more material properties of a tissue, wherein the one or more material properties include at least one of mechanical properties,...
US20170307710 LOCAL TEMPERATURE RISE CONSTRAINED RADIO FREQUENCY PULSE DESIGN IN PARALLEL TRANSMISSION  
Systems and methods for designing RF pulses using a technique that directly controls temperature rise via a compression model that is based on virtual observation points (“VOPs”) are provided....
US20170307708 SYSTEMS AND METHODS FOR DESIGNING MULTIDIMENSIONAL SELECTIVE ADIABATIC PULSES  
Described here are systems and methods for designing and implementing spatially selective, multidimensional adiabatic radio frequency (“RF”) pulses for use in magnetic resonance imaging (“MRI”)....
9797819 Sensor for tension measurement  
A device includes a first sensor and a second sensor. The first sensor is configured to generate a first signal corresponding to a detected first force. The second sensor is configured to generate...
9796993 Lignin-degrading methods  
A method involving degrading materials that include lignin generally includes contacting a lignin sample with a flavin-dependent monooxygenase and contacting the lignin sample with an auxiliary...
9796957 Genetically modified diazotrophs and methods of using same  
This disclosure describes a genetically-modified diazotrophic microbe and methods that involve the genetically-modified diazotrophic microbe. Generally, the diazotrophic microbe is modified to...
9796671 Aurora kinase inhibitors  
The invention provides compounds of the formula: and salts thereof that are useful as intermediates for preparing corresponding compounds of formula I: that are useful for treating conditions...
US20170301675 ULTRA HIGH DENSITY INTEGRATED COMPOSITE CAPACITOR  
Capacitors that can be formed fully on an integrated circuit (IC) chip are described in this disclosure. An IC chip includes a metal-oxide-silicone (MOS) capacitor formed from a MOS transistor...
US20170299904 SPIN MAGNETO-OPTICAL MODULATOR  
Techniques are described for a device that includes an optical channel configured to transport an optical signal. The device further includes a magnetic material with low optical absorption...
US20170299585 COMPOSITIONS, KITS, AND METHODS FOR CELL SEPARATION  
A cell-capturing substrate, methods of using the cell-capturing substrate that allow for label-free cell separation, and kits that incorporate the cell-capturing substrate.
US20170298391 CONDITIONAL RESCUE SYSTEM, CELLS, AND METHODS  
A conditional rescue system generally includes a gene transfer system, a polynucleotide including a nuclease-resistant target coding region, and a coding region encoding a conditionally-lethal...
US20170298168 GLUCOSE-BASED BLOCK COPOLYMERS  
An example block copolymer may include at least one poly(glucose-6-acrylate) (G6A) block. An example technique may include treating glucose-6-acrylate-1,2,3,4-tetraacetate (GATA) monomer and...
US20170297983 METHODS OF FORMING DIOL COMPOUNDS  
Methods of forming a C4 to C7 diol compound, the methods including a first step of reacting a C4 to C7 dicarboxylic acid with hydrogen (H2) gas on a first heterogeneous catalyst at a first...
US20170296825 BIOELECTRICAL MODULATION USING ROTATING OR SPATIALLY-SELECTIVE ELECTROMAGNETIC FIELDS  
Described here are bioelectric modulation systems and methods for generating rotating or spatially-selective electromagnetic fields. A modulation system includes a multichannel electrode with...
US20170296140 VASCULAR CHARACTERIZATION USING ULTRASOUND IMAGING  
Ultrasound methods and/or systems provide for the motion tracking of both vessel wall motion and blood flow (e.g., with use of high frame rate ultrasound pulse echo data and speckle tracking both...
9790484 Silica encapsulated biomaterials  
The present invention relates to compositions for encapsulation of biomaterials in a silica-matrix. The present invention includes a composition for formation of a silica-matrix encapsulated...
9789176 Compositions and methods for inducing immune responses against bacteria in the genus staphylococcus  
This disclosure features compositions that include two or more staphylococcal toxoids and are useful for inducing protective immune responses against staphylococcal diseases.
9789136 Multipotent adult stem cells and methods for isolation  
The invention provides isolated stem cells of non-embryonic origin that can be maintained in culture in the undifferentiated state or differentiated to form cells of multiple tissue types. Also...
9788792 System for screening skin condition for tissue damage  
The present invention relates to a novel approach means of screening various skin surfaces, including hard to reach areas of the human body, as well as more commonly seen areas such as the foot....
US20170294699 NANOPILLAR-BASED ARTICLES AND METHODS OF MANUFACTURE  
Nanopillar-based THz metamaterials, such as split ring resonator (SRR) MMs, utilizing displacement current in the dielectric medium between nanopillars that significantly increases energy storage...
US20170294698 MICROSCALE THREE-DIMENSIONAL ELECTRIC DEVICES AND METHODS OF MAKING THE SAME  
Functionalized microscale 3D devices and methods of making the same. The 3D microdevice can be realized with the combination of top-down (lithographic) and bottom-up (origami-inspired...