Patents and Patent Applications from University of Minnesota


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US20180172526 STITCHED STRETCH SENSOR  
A stitched sensor including a plurality of threads stitched to a textile in a stitch geometry is described. The plurality of threads includes a conductive thread, and the stitch geometry is...
US20180171029 ANTI-APOBEC3 ANTIBODIES AND METHODS OF MAKING AND USING  
Hybridoma cell lines produce monoclonal antibodies that specifically bind to an APOBEC3 protein. The antibodies can be used in various methods. In some aspects, an anti-APOBEC3 antibody may be...
US20180170984 SITE-SPECIFIC DNA BASE EDITING USING MODIFIED APOBEC ENZYMES  
Materials and methods for using modified Cas9-APOBEC fusion polypeptides for targeted modification of specific DNA sequences are provided herein.
US20180168917 DEVICE AND METHOD FOR GAIT SYNCHRONIZED SENSORY STIMULATION OF THE LOWER EXTREMITIES  
A device can comprise: a trigger chamber, having a trigger elastic wall and a trigger base wall, the trigger chamber configured for relative motion between the trigger elastic wall and the trigger...
9999369 Laser-scribed ferrogel sensor with magnetic particles  
A method of making a sensor includes depositing a layer of hydrogel over a substrate, the hydrogel configured to change thickness or volume in response to a selected condition and including a...
10002694 Inductor including alpha″-Fe16Z2 or alpha″-Fe16(NxZ1-x)2, where Z includes at least one of C, B, or O  
An inductor may include a magnetic material that may include α″-Fe16(NxZ1-x)2 or α′-Fe8(NxZ1-x), or a mixture of at least one of α″-Fe16N2 or α′-Fe8N and at least one of α″-Fe16Z2 or α′-Fe8Z,...
US20180166500 TWO-TERMINAL SPINTRONIC DEVICES  
This disclosure describes an example device that includes a first contact line, a second contact line, a spin-orbital coupling channel, and a magnet. The spin-orbital coupling channel is coupled...
US20180166197 SPIN ORBIT TORQUE GENERATING MATERIALS  
A material may include at least one of BixSe(1-x), BixTe(1-x), or SbxTe(1-x), where x is greater than 0 and less than 1. In some examples, the material exhibits a Spin Hall Angle of greater than...
US20180162998 A POLYOLEFIN REACTIVE TELECHELIC PRE-POLYMER  
A dicarbamate telechelic unsaturated polyolefin pre-polymer comprising a reaction product of reacting alkyl-cis-cyclooctene and optionally cis-cyclooctene, in the presence of a multifunctional...
9996941 Constrained key frame localization and mapping for vision-aided inertial navigation  
Estimation techniques for vision-aided inertial navigation are described. In one example, a vision-aided inertial navigation system (VINS) comprises an image source to produce image data for a...
9995803 Auto-tune- and-match coils for human whole-body imaging and method  
A progressive series of five new coils is described. The first coil solves problems of transmit-field inefficiency and inhomogeneity for heart and body imaging, with a close-fitting, 16-channel...
9994949 Applied magnetic field synthesis and processing of iron nitride magnetic materials  
A method may include annealing a material including iron and nitrogen in the presence of an applied magnetic field to form at least one Fe16N2 phase domain. The applied magnetic field may have a...
US20180156883 SYSTEMS AND METHODS FOR AUTOMATIC VOXEL POSITIONING IN MAGNETIC RESONANCE SPECTROSCOPY  
Systems and methods for automated voxel positioning in magnetic resonance spectroscopy (“MRS”) are provided. In some aspects, a method includes receiving magnetic resonance (“MR”) imaging data...
US20180156672 SPINTRONIC TEMPERATURE SENSOR  
This disclosure describes various examples of spintronic temperature sensors. The example temperature sensors may be discrete or used to adaptively control operation of a component such as an...
US20180153944 METHODS FOR DETECTING RISK OF HAVING A BLOODSTREAM INFECTION AND COMPOSITIONS FOR REDUCING THE RISK  
Provided herein is a method for determining the relative abundance of total bacterial in a sample. Optionally, the method also includes determining whether the subject has a risk of bloodstream...
9989610 Multiband slice accelerated imaging with balanced slice-selective gradients  
A computer-implemented method for performing multi-band slice accelerated imaging includes performing a low-resolution fast multi-dimensional reference scan to obtain a coil sensitivity map. A...
9988393 Isosorbide-based polymethacrylates  
A monomer comprises the structure wherein R1 comprises H or a substituted hydrocarbyl or unsubstituted hydrocarbyl, and wherein R2 comprises H, a halide, or a substituted or unsubstituted (C1-C4)...
9988307 Emulsion polymer two-component compositions for fast curing cementitious waterproofing membranes  
The present invention provides two-component compositions comprising a component A) one or more acrylic aqueous emulsion copolymer having a measured glass transition temperature (Tg) of from −20...
9987211 Sunless tanning compounds and compositions  
The invention provides sunless tanning compositions comprising a compounds of formula (I): or a salt thereof as described herein as well as methods for tanning mammalian skin by contacting the...
9987153 Vascular elastance  
A device includes a balloon and an interface. The balloon has an outer surface and a central lumen aligned on a longitudinal axis. The balloon is configured to receive a compressible fluid. The...
9986945 Devices, systems, and methods for obtaining and analyzing urine flow rate data using acoustics and software  
Flow rate measurement devices and systems for accurate urine analysis to determine benign prostatic hyperplasia (BPH) or urethral stricture disease (USD) generally comprise a recording unit, an...
9981067 Biomimetic hybrid gel compositions and methods of use  
Disclosed herein are dry blends of polyanionic and polycationic macromolecules, solvating fluids serving as cell suspension fluids, hybrid gel compositions, and methods for treatment of patients...
9981043 Analgesic conjugates  
The invention provides analgesic conjugates having a mu opioid receptor agonist linked to a mGluR5 antagonist, and to methods for producing analgesia using such compounds.
9980503 Chewing gums and gum bases comprising multi-block copolymers  
Chewing gums and chewing gum bases which are cud-forming and chewable at mouth temperature contains a multi-block copolymer having at least two repeating sequences of at least two different...
US20180142262 METHOD FOR CORRECTING A GENETIC SEQUENCE  
Methods of gene correction, methods of generating induced pluripotent stem cells (iPSCs), and methods of deriving multi-lineage cell types with therapeutic value. In some embodiments, the gene...
US20180141836 ELECTROCHEMICAL REMOVAL OF SULFIDE SPECIES AND PHOSPHORUS SPECIES  
According to various embodiments a system includes a housing. A chamber is disposed within the housing and receives a working fluid. The working fluid includes at least one of one or more sulfide...
9977101 Active transmit elements for MRI coils and other antenna devices, and method  
Apparatus and method that includes amplifiers for transceiver antenna elements, and more specifically to power amplifying an RF (radio frequency) signal using a distributed power amplifier having...
9974962 Alternans prevention and termination  
In a method of preventing the formation of alternans in the heart of a patient, the heart is paced to control the TR interval of each heartbeat. The method may be performed using a heart...
US20180137690 MATERIAL ANALYSIS OF ANATOMICAL ITEMS  
A computer-implemented method for medical device modeling includes accessing an electronic definition for a model of a three-dimensional item and an electronic definition of a three-dimensional...
US20180134840 PROCESS TO PRODUCE A POLYOLEFIN REACTIVE TELECHELIC PRE-POLYMER  
A process to produce a polyolefin reactive telechelic pre-polymer comprising reacting alkyl-c/5-cyclooctene and optionally czs-cyclooctene, in the presence of a multifunctional chain transfer...
9968638 Compositions and methods for transplantation of colon microbiota  
The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a...
US20180130193 SIMULTANEOUS ESTIMATION OF LOCATION ELEVATIONS AND WATER LEVELS  
A method improves automated water body extent determinations using satellite sensor values and includes a processor receiving a time-sequence of land cover labels for a plurality of geographic...
US20180128827 LATERAL FLOW ASSAYS WITH THERMAL CONTRAST READERS  
Assays used in conjunction with a thermal contrast reader are disclosed. In the assay, the test strip includes materials that can develop a thermal response if a target analyte is present in a...
US20180127865 Nanoparticle Deposition Systems  
Nanoparticle deposition systems including one or more of: a hollow target of a material; at least one rotating magnet providing a magnetic field that controls movement of ions and crystallization...
US20180127686 BIOACTIVE MATERIALS  
Bioactive coatings that include a base and a protein associated with the base for actively promoting the removal of organic stains are provided. In aspects, bioactive coatings that are stabilized...
US20180127685 BIOACTIVE MATERIALS  
Bioactive coatings that include a base and a protein associated with the base for actively promoting the removal of organic stains are provided. In aspects, bioactive coatings that are stabilized...
9967038 Optical interconnect in spin-based computation and communication systems  
Techniques are described for data transfer in spin-based systems where digital bit values are represented by magnetization states of magnetoresistive devices rather than voltages or currents. For...
US20180121585 GRAPH BASED DYNAMIC TIMING AND ACTIVITY ANALYSIS  
A method for analyzing a digital circuit includes performing a hardware simulation for a workload on a digital circuit design to generate an activity file including a plurality of time stamps and...
US20180119689 ALTERNATING FLOW HYDRAULIC PUMP CIRCUIT  
A hydraulic pump assembly including a first pump, a second pump, a shaft, and fluid lines is disclosed. The first pump includes a first piston assembly. The second pump including a second piston...
US20180119153 ANDROGEN RECEPTOR VARIANT INHIBITORS AND METHODS OF USING  
This document relates to materials and methods for treating cancer (e.g., prostate cancer). For example, methods for using one or more androgen receptor variant (AR-V) inhibitors (e.g.,...
US20180118789 CHIMERIC MELANOCORTIN LIGANDS AND METHODS OF USE THEREOF  
The invention provides compounds having the general formula I: and salts thereof, wherein the variables Pro, DPro, DPhe, Arg, Trp, X1, X2, X3 and X4 have the meaning as described herein, and...
US20180118604 DOPED NANOPOROUS SILICA  
Techniques for precise and accurate doping of nanoporous silica gel or silica glass that include forming a silica gel slurry that includes an activated silica gel and a solvent, adding a metal...
9957324 Anti-FLT-1 antibodies in treating duchenne muscular dystrophy  
The present invention provides, among other things, methods and compositions for treating muscular dystrophy, in particular, Duchenne muscular dystrophy (DMD). In some embodiments, a method...
US20180114293 LARGE SCALE IMAGE MOSAIC CONSTRUCTION FOR AGRICULTURAL APPLICATIONS  
A method for generating improved image mosaics includes using a set of overlapping images of a landscape to determine three-dimensional locations for a plurality of features of the landscape....
US20180111837 DIRECT SYNTHESIS OF HIGH-ASPECT RATIO ZEOLITE NANOSHEETS  
An example material includes a planar layer of MFI zeolite. The planar layer has a thickness in a range between 4 nm and 10 nm for at least 70% of a basal area of the planar layer.
US20180110991 DEEP BRAIN STIMULATION SYSTEM AND METHOD WITH MULTI-MODAL, MULTI-SYMPTOM NEUROMODULATION  
Described here is a deep brain stimulation (“DBS”) approach that targets several relevant nodes within brain circuitry, while monitoring multiple symptoms for efficacy. This approach to...
US20180110973 SYSTEMS AND METHODS FOR OPTIMIZING PROGRAMMING AND USE OF NEUROMODULATION SYSTEMS  
Systems and methods for programming multi-electrode neuromodulation systems, with applications for at least deep brain stimulation (DBS) therapy. One or more configurations can be generated and...
US20180110810 FREEZE DRIED FECAL MICROBIOTA FOR USE IN FECAL MICROBIAL TRANSPLANTATION  
The present invention provides freeze-dried compositions that include an extract of human feces and a cryoprotectant, and methods for making and using such compositions, including methods for...
US20180110806 Multipotent Adult Stem Cells and Methods for Isolation  
The invention provides isolated stem cells of non-embryonic origin that can be maintained in culture in the undifferentiated state or differentiated to form cells of multiple tissue types. Also...
9951019 Therapeutic compounds  
The invention provides compounds of formula (I): wherein, A, C, D, X, and Y have any of the values defined in the specification, and salts thereof. The compounds are SIRT2 inhibitors and are...