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US20120128719 |
STREPTOCOCCUS VACCINE COMPOSITIONS AND METHODS OF USING THE SAME
The present invention provides methods and compositions for the stimulation of immune responses. In particular, the present invention provides immunogenic nanoemulsion compositions and methods of...
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US20120126449 |
SHAPING NANOSTRUCTURE ARRAYS
Nanostructured assemblies are manufactured by condensing an evaporated wetting agent onto a nanostructure array formed from a plurality of generally aligned carbon nanotubes or other...
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8185812 |
Single event upset error detection within an integrated circuit
An integrated circuit 2 includes logic circuitry 10 and sequential storage elements 8. Both the logic circuit 10 and sequential storage elements 8 can be subject to particle strikes giving rise to...
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8185786 |
Error recovery within processing stages of an integrated circuit
An integrated circuit includes a plurality of processing stages each including processing logic, a non-delayed signal-capture element, a delayed signal-capture element and a comparator. The...
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8185186 |
Systems and methods for tissue imaging
The present invention provides systems and methods for monitoring tissue regions. In particular, the present invention provides systems and methods for detecting changes in tissue regions over a...
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8183344 |
Inactivation resistant factor VIII
The present invention provides novel purified and isolated nucleic acid sequences encoding procoagulant-active FVIII proteins. The nucleic acid sequences of the present invention encode amino acid...
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US20120122947 |
SPIRO-OXINDOLE MDM2 ANTAGONISTS
Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists...
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US20120121571 |
Lysosomal Phospholipase A2 (LPLA2) Activity as a Diagnostic and Therapeutic Target for Identifying and treating Systemic Lupus Erythematosis
The present invention is directed to methods for diagnosis and treatment of systemic lupus erythematosus and drug-induced systemic lupus erythematosus. More specifically, the specification...
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8179661 |
Organic branched and hyperbranched systems for high dielectric and capacitance applications
An organic dielectric material comprises a branched and/or hyperbranched macromolecule having delocalized electrons. Such macro-molecular organic material systems have desirable delocalized charge...
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US20120114623 |
ANTIGEN-SPECIFIC LONG-TERM MEMORY T-CELLS
The present invention provides compositions, methods, and systems for generating antigen-specific long-term memory T-cells using mTOR pathway inhibitors. The present invention provides...
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US20120107349 |
MULTIVALENT NANOEMULSION VACCINES
The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides methods of inducing an immune response against one or a...
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8168626 |
Benzodiazepine compositions for treating epidermal hyperplasia and related disorders
The present invention provides, for example, pharmaceutical compositions comprising a benzodiazepine compound and an agent selected from the group consisting of a topical steroid, a keratolytic...
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8168423 |
Device for detecting nitrosothiol content in solution
A device for detecting nitrosothiol content in a solution includes at least two electrodes disposed in a housing, wherein one of the at least two electrodes is a working electrode having a...
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8167804 |
Measurement of tissue elastic modulus
An optimized elastic modulus reconstruction procedure can estimate the nonlinear elastic properties of vascular wall from intramural strain and pulse wave velocity (PWV) measurements. A noninvasive...
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8167092 |
Metalworking lubricant formulations based on supercritical carbon dioxide
A method for lubricating a metal workpiece during a metalworking process includes delivering supercritical carbon dioxide to the workpiece during the metalworking process. The supercritical carbon...
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US20120101092 |
SMALL MOLECULE INHIBITORS OF MDM2 AND THE USES THEREOF
The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth,...
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US20120100107 |
IN VIVO TRANSFER METHODS FOR WOUND HEALING
The present invention relates to an in vivo method for specific targeting and transfer of DNA into mammalian repair cells. The transferred DNA may include any DNA encoding a therapeutic protein of...
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8164022 |
Optical sensor for quality monitoring of a welding process
Disclosed is the design and working principle of a welding monitoring system that can monitor the spectra of zinc and iron in the plasma generated during a welding process involving zinc-coated...
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8163805 |
Small molecule antagonists of Bcl-2 family proteins
The present invention relates to naturally occurring and chemically synthesized small molecule antagonists of Bcl-2 family proteins. In particular, the present invention provides gossypol compounds...
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8163281 |
Treatment of drug-related side effect and tissue damage by targeting the CD24-HMGB1-Siglec10 axis
The present technology provides methods and compositions for the treatment of tissue-damage related immune dysregulation by administering a composition comprising one or more of CD24; CD24...
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US20120094982 |
1,4-BENZODIAZEPINONE COMPOUNDS AND THEIR USE IN TREATING CANCER
The invention provides a family of 1,4-benzodiazepinone compounds and methods for their use as therapeutic agents in treating cancer. Pharmaceutical compositions and methods of making the...
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US20120091436 |
ORDERED ORGANIC-ORGANIC MULTILAYER GROWTH
An ordered multilayer crystalline organic thin film structure is formed by depositing at least two layers of thin film crystalline organic materials successively wherein the at least two thin film...
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8159235 |
Electrical impedance tomography of nanoengineered thin films
The present teachings relate to the application of electrical impedance tomography (EIT) to demonstrate the multifunctionality of carbon nanocomposite thin films under various types of...
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8158972 |
Organic photosensitive optoelectronic devices containing tetra-azaporphyrins
Embodiments of the present invention provide an organic photosensitive optoelectronic device comprising at least one tetra-azaporphyrin compound of formula (I) are disclosed herein.
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8158596 |
Materials and methods for FOXP3 tumor suppression
Provided herein are methods of treating a cancer in a subject comprising administering a FOXP3 protein, a nucleic acid encoding a FOXP3 protein, or an inducing compound which induces FOXP3 protein...
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US20120088757 |
NOVEL 1,4-BENZODIAZEPINE-2,5-DIONES WITH THERAPEUTIC PROPERTIES
The present invention relates to novel chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides novel 1,4-benzodiazepine-2,5-dione...
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US20120087061 |
Transition Metal Carbide or Nitride or Boride Based Supercapacitors with Metal Foam Electrode Substrate
In accordance with an embodiment of the disclosure, a method of making a supercapacitor includes impregnating a foam electrode substrate with an active material precursor, wherein the foam...
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8155497 |
Fiber-based electric device
A method of manufacturing a fiber-based electric apparatus includes providing an elongate, flexible fiber core and layering an electric device on the fiber core.
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8148147 |
Compositions and methods for treating and diagnosing pancreatic cancer
The present invention relates to the field of oncology and provides novel compositions and methods for diagnosing and treating pancreatic cancer. In particular, the present invention provides...
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8147828 |
Methods and compositions for modulation of blood-neural barrier
Methods and compositions for modulating blood-neural barrier (BNB) for the treatment of CNS conditions such as edema, and for increased drug delivery efficacy across the BNB. The present invention...
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US20120077806 |
Deubiquitinase Inhibitors and Methods for Use of the Same
Disclosed herein are methods of inhibiting a deubiquitinase (DUB), methods of treating pathogenic infections (e.g., viral, bacterial, and/or parasitic), methods of inhibiting cell proliferation,...
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US20120077805 |
UNSOLVATED BENZODIAZEPINE COMPOSITIONS AND METHODS
The present invention relates to systems and methods for generating new forms of benzodiazepine and benzodiazepine related compounds as well as new compounds and formulations generated by such...
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US20120077231 |
Thermal Microvalves
The movement and mixing of microdroplets through microchannels is described employing silicon-based microscale devices, comprising microdroplet transport channels, reaction regions, electrophoresis...
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8145960 |
Storage of data in data stores having some faulty storage locations
Data storage control circuitry for controlling storage and retrieval of data in a data store in which data is stored in data blocks. A group data store stores data by grouping together blocks that...
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8143613 |
Organic light emitting device having multiple separate emissive layers
An organic light emitting device having multiple separate emissive layers is provided. Each emissive layer may define an exciton formation region, allowing exciton formation to occur across the...
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8143232 |
Gene fusion targeted therapy
The present invention relates to compositions and methods for cancer therapy, including but not limited to, targeted inhibition of cancer markers. In particular, the present invention relates to...
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US20120070389 |
METHODS FOR IDENTIFYING TREATMENTS THAT TREAT AND/OR PREVENT UV IRRADIATION INDUCING PHOTOAGING
Methods are provided for ascertaining and measuring RPTP-κ activity in response to insults such as UV irradiation and with respect to administration of a treatment and/or composition. Attenuation ...
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8141156 |
Method and apparatus for mitigating routing misbehavior in a network
Method and apparatus for mitigating routing misbehavior in a network is described. In one example, routing protocol traffic is received from a remote router destined for a local router. The routing...
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US20120061658 |
STRUCTURAL TEMPLATING FOR ORGANIC ELECTRONIC DEVICES HAVING AN ORGANIC FILM WITH LONG RANGE ORDER
An organic photosensitive device having an organic film with a desired crystalline order includes a first electrode layer and at least one structural templating layer disposed on the first...
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8133496 |
Compositions and methods for diagnosing and treating urinary tract infections
The present invention relates to methods and compositions for treating urinary tract infections. In particular, the present invention relates to vaccines and immune modulators for treating urinary...
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US20120059779 |
Personalized Health Risk Assessment For Critical Care
A method for assessing whether a patient is at risk of developing a clinical condition includes receiving training data representing a set of patient-related variables for each of a plurality of...
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8130986 |
Trapped fluid microsystems for acoustic sensing
Silicon and glass micromachined (MEMS) acoustic sensors incorporating trapped-liquid architectures are disclosed. The trapped liquid serves as an acoustic transmission medium allowing the input...
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US20120052052 |
CONTROL OF BIOFILM FORMATION
The invention relates to control of biofilm development. Specifically, some embodiments of the present invention relate to control of bacterial biofilm formation through addition or breakdown of...
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US20120050107 |
Phased Antenna Arrays Using a Single Phase Shifter
Techniques for the design of low cost, low complexity phased arrays are described. The techniques allow control of the phase progression in the entire phased array by using only one phase shifter...
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US20120049149 |
SILICON BASED NANOSTRUCTURE CROSSBAR MEMORY
The present application describes a crossbar memory array. The memory array includes a first array of parallel nanowires of a first material and a second array of parallel nanowires of a second...
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8126690 |
Algorithms to predict clinical response, adherence, and shunting with thiopurines
A method of using a variable set from complete blood counts and blood chemistry panels to generate a machine learned algorithm for determining the effectiveness of thiopurine treatment on...
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8124375 |
Geraniol synthase, methods of production and uses thereof
The present invention relates to novel type of monoterpene synthase, a key enzyme in the production of the monoterpene aroma compound geraniol. More specifically, the present invention relates to...
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US20120047310 |
Crossbar circuitry for applying a pre-selection prior to arbitration between transmission requests and method of operation of such crossbar circuitry
Crossbar circuitry has data input and output paths, and at each intersection between a data input and output path, a crossbar cell is provided. A transmission circuit is responsive to a stored...
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US20120046196 |
ADRB2 Cancer Markers
The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to...
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US20120045487 |
MULTIPHASIC MICROFIBERS FOR SPATIALLY GUIDED CELL GROWTH
A multiphasic microfiber for a three-dimensional tissue scaffold and/or cellular support is provided in one aspect that includes at least one biocompatible material. The multiphasic microfiber...
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