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Patents and Patent Applications from University of Miami


Matches 151 - 200 out of 446 < 1 2 3 4 5 6 7 8 9 >
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US20110123441 NOVEL GREB1A MONOCLONAL ANTIBODY  
The generation and validation of a novel monoclonal GREB1 antibody (GREB1ab). Methods for the prognosis, diagnosis, assessment of disease progression, severity and outcome utilize GREB1 molecules...
US20110108602 ANASTOMOSIS SYSTEM AND METHOD  
A system for performing anastomosis includes a plurality of staples, an annular staple support having structure for holding the staples, and a staple closing device for closing the staples to...
US20110095243 Photochromic compounds based on ring opening and closing of an [1,3]oxazine compound  
We have designed a molecular switch based on the photoinduced opening and thermal closing of a [1,3]oxazine ring. A substituted [1,3]oxazine compound described as having a general (i.e.,...
7924429 Enhanced optical coherence tomography for anatomical mapping  
A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of...
7910359 Hybrid device for cell therapies  
A device for receiving implanted biological material includes a porous outer wall defining an inner space, a fluid manifold assembly for selectively infusing at least one of immunosuppressive and...
US20110066230 Fluorinated GHRH Antagonists  
Novel fluorinated synthetic analogs of hGH-RH(1-30)NH2 that inhibit the release of growth hormone from the pituitary in mammals as well as inhibit the proliferation of human cancers through a...
US20110065675 AZO DYE RELATED SMALL MOLECULE MODULATORS OF PROTEIN-PROTEIN INTERACTIONS  
Azo dyes and suramin-related small molecules are effective in inhibiting the CD40/CD154 protein-protein interaction, an important co-stimulatory interaction involved in the activation of immune...
US20110052705 CARTILAGE COMPOSITION AND PROCESS FOR PRODUCING THE CARTILAGE COMPOSITION  
Disclosed is a method for regenerating articular cartilage in an animal comprising administering a therapeutically effective amount of a non-demineralized particulate articular cartilage having a...
US20110039805 METHOD FOR TREATING MEIBOMIAN GLAND DISEASE  
A method for treating a patient having meibomian gland disease, ocular irritation associated with delayed tear clearance, or recurrent corneal epithelial erosion, is disclosed. Preferably, the...
US20110039788 COMPOSITIONS, METHODS AND KITS FOR DETECTING AND TREATING CANCER  
Compositions, kits and methods for inhibiting cancer cell (e.g., breast cancer cell) growth and treating a subject with cancer (e.g., breast cancer) include a therapeutically effective amount of an...
US20110038865 ANTIBODY- ENDOSTATIN FUSION PROTEIN AND ITS VARIANTS  
Chimeric molecules comprising endostatin and all or a portion of a tumor antigen specific binding molecule for use in treating tumors. The chimeric molecule, includes endostatin, endostatin mutants...
US20110036320 WASTE RECOVERY COGENERATOR  
A waste-to-energy cogeneration system is described in various embodiments. The system can convert certain fuel-laden waste to thermal energy and electrical power. In certain embodiments, fuel-laden...
US20110034931 METHOD FOR PREPARING RECIPIENT SITE AND IMPLANTING ALLOGENIC BONE GRAFT  
A method of fixating allogeneic bone to an area of deficient bone in the jaws comprising: exposing the area of deficient bone by incising and retracting soft tissue; selecting a drill bit having a...
US20110027313 VIRAL RECOMBINEERING AND USES THEREOF  
The invention uses recombinant technology to create infectious molecular clones that capture the sequence diversity of viral genes found in natural populations of mixed genotype viruses, such as...
US20110021584 Methods and Assays for Detecting and Treating Hypoglycemia  
Methods for regulating glucagon release and of treating hypoglycemia, and for screening drug candidates for treating hypoglycemia. The methods are useful for treating diabetes mellitus and...
US20110020856 PERIFUSION DEVICE  
A perifusion device includes at least one sample container for cells, the sample container having an inlet and an outlet. The container receives test liquid through the inlet and discharges the...
US20110008884 PATHOLOGY GROSSING TOOL, CASSETTE, AND BOARD  
A pathology grossing tool and board are provided for the preparation from a gross tissue of a uniformly thin tissue specimen, which is suitable for processing for histology, histochemistry,...
US20100316622 DIAGNOSIS AND TREATMENT OF CARDIAC DISORDERS  
Nitric oxide synthase deficiency causes diminished ryanodine receptor S-nitrosylation leading to increased diastolic calcium (Ca2+) and reduced intra sarcoplasmic reticulum calcium (Ca2+) content....
US20100310532 GENE TARGETS IN ANTI-AGING THERAPY AND TISSUE REPAIR  
Novel gene and protein targets are described for treatment of cardiac disorders, anti-aging therapies and tissue repair. Identified biomarkers are prognostic of long term survival of patients...
US20100298438 GENE EXPRESSION PROFILING OF PARKINSON'S DISEASE  
The present invention identifies the changes in gene expression associated with Parkinson's Disease by examining multiregional gene expression from normal brain and brain of Parkinson's Disease....
7838040 Method for regenerating cartilage  
Disclosed is a method for regenerating articular cartilage in an animal comprising administering a therapeutically effective amount of a non-demineralized particulate articular cartilage having a...
US20100285132 IMMUNOTHERAPY COMPOSITIONS, METHOD OF MAKING AND METHOD OF USE THEREOF  
The present invention directs to compositions and methods for modulating immune system. One aspect of the present invention relates to a composition comprising FADD-dependent signaling pathway...
US20100272709 CATHEPSIN L MEDIATED DISEASES AND ASSOCIATED METHODS AND PRODUCTS  
This invention relates generally to the treatment of cathepsin or dynamin mediated diseases, such as proteinuria, cancer, and cognitive disease and related products. Diagnostic and other assays are...
US20100260727 METHOD TO AMPLIFY CARDIAC STEM CELLS IN VITRO AND IN VIVO  
Compositions comprising stem cells delivered into infarcted myocardium by endocardial injection, engraft and differentiate into myocytes, endothelial cells, and vascular smooth muscle, and do so...
7807458 Multilineage-inducible cells and uses thereof  
Described herein are post natal, multilineage inducible cells (MIAMI cells). In some examples, the cells are isolated from non fractionated, adult (males and females 3 to 72 years old) human bone...
US20100249403 USE OF OXAZINE COMPOUNDS FOR MAKING CHROMOGENIC MATERIALS  
Heterocyclic compounds incorporating a [1,3]oxazine ring may be used to make chromogenic materials. These molecules switch from a colorless state to a colored form upon addition of either acid or...
US20100247302 WIND ENERGY SYSTEM  
A method and system for harvesting wind energy. The system may include a wind turbine disposed subjacent to a roof assembly of building. A plurality of conduits are adjacent to and extending below...
US20100240732 APTAMER-TARGETED SIRNA TO PREVENT ATTENUATION OR SUPPRESSION OF A T CELL FUNCTION  
Compositions for countering immune attenuating/suppressive pathways comprise targeting agents or aptamer targeted RNAi-mediated gene silencing (siRNA/shRNA). These compositions have broad...
7790437 Organ transportation device  
An organ transportation device includes a fluid-tight organ container and structure within the organ container for engaging an organ within the organ container. A base assembly is provided, and...
7790068 Photochromic compounds based on ring opening and closing of a {1,3}oxazine compound  
We have designed a molecular switch based on the photoinduced opening and thermal closing of a [1,3]oxazine ring. A substituted [1,3]oxazine compound described as having a general (i.e.,...
US20100208201 ENHANCED OPTICAL COHERENCE TOMOGRAPHY FOR ANATOMICAL MAPPING  
A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of...
US20100190838 Connective Tissue Growth Factor Fragments and Methods and Uses Thereof  
The present invention is directed to CTGF fragments comprising at least exon 2 or exon 3 of CTGF and having the ability to induce extracellular matrix synthesis, in particular, collagen synthesis...
US20100190650 TRANSCRIPTOMIC BIOMARKER OF MYOCARDITIS  
Molecular signatures that function as very sensitive diagnostic biomarker for myocarditis, heart disease and disorders thereof, are identified.
US20100183584 CONFORMATION AND ACTIVITY OF GBETA5 COMPLEXES  
The invention provides novel recombinant Gβ5 complex proteins, novel methods of identifying compounds that modulate the conformation of Gβ5 complex, novel methods of treating disorders, including n...
7758641 Extraocular muscle prosthesis  
A prosthetic device and method to restore extraocular muscle function. The device includes a housing; a biasing component disposed in the housing; a proximal connector operatively connected to a...
US20100160230 UBIQUITIN AND UBIQUITIN RELATED MOLECULES FOR TREATMENT AND PREVENTION OF HARMFUL ACTIVATION OF THE IMMUNE SYSTEM  
Compositions and methods for suppressing the immune system of a mammal using ubiquitin and derivatives and analogs thereof.
US20100152114 Antioxidant activity of GH-RH Antagonists  
There are provided means for suppressing the Reactive Oxidant Species (ROS) of certain cells by the administration of GHRH antagonists. The therapeutic applications of the anti-oxidative action of...
US20100143464 CROSS-LINKED ALGINATE-POLYALKYLENE GLYCOL POLYMER COATINGS FOR ENCAPSULATION AND METHODS OF MAKING THE SAME  
A biocompatible capsule comprising a biological material encapsulated by a covalently stabilized coating and a method of making the same are disclosed. The biological material can be a material...
D616805 Co-flow jet aircraft  
US20100130434 Hexose Compounds to Treat Cancer  
Methods of treating glioblastoma and pancreatic cancer are provided by the administration of a therapeutically effective amount of a hexose compound to a subject in need thereof The subject...
US20100127129 High performance airfoil with co-flow jet flow control  
An aerodynamic system providing an airfoil having a chord length, a leading edge, and a trailing edge. The airfoil further includes a first airfoil surface extending from the leading edge to the...
7718177 Antibodies directed to fragments of connective tissue growth factor (CTGF) polypeptide and methods and uses thereof  
The present invention is directed to CTGF fragments comprising at least exon 2 or exon 3 of CTGF and having the ability to induce extracellular matrix synthesis, in particular, collagen synthesis...
US20100119537 TUMOR VACCINE  
The invention relates to the fields of medicine, immunology, and oncology. More specifically, the invention relates to methods and compositions for inducing an immune response against a tumor in an...
7716398 Bifurcate buffer  
A buffer includes a plurality of serial inputs, a plurality of de-serializers, each coupled to a respective input, a plurality n of buffers and a media access controller having inputs coupled to...
7713686 Organ preservation container and method  
An organ preservation container includes a gas impermeable housing for containing an organ. At least two liquids having different densities and forming a liquid-liquid interface are also contained...
US20100113567 Recombinant VSV For The Treatment of Tumor Cells  
The present invention relates to compositions and methods for the treatment of tumor and/or malignant and/or cancerous cells. The present invention provides VSV vectors comprising nucleic acid...
US20100112587 TRANSCRIPTOMIC BIOMARKERS FOR INDIVIDUAL RISK ASSESSMENT IN NEW ONSET HEART FAILURE  
A novel transcriptomic biomarker for prognosis in heart failure has a direct clinical application in prediction of prognosis in new onset heart failure, heart disease, heart disorders and...
US20100112560 MECHANISM TO SIGNAL RECEPTOR-LIGAND INTERACTIONS WITH LUMINESCENT QUANTUM DOTS  
Semiconductor quantum dots are becoming valuable analytical tools for use in biomedical applications. Indeed, their unique properties offer the opportunity to design luminescent probes for imaging...
US20100112406 ULTRASONICALLY ENHANCED FUEL CELL SYSTEMS AND METHODS OF USE  
A fuel cell system comprises at least one fuel source (e.g., methanol or methanol solution) In a storage tank, tubes and/or flow channels that provide the fuel to the fuel cells via tubes and/or...
US20100092539 Fluorinated GHRH Antagonists  
Novel fluorinated synthetic analogs of hGH-RH(1-30)NH2 that inhibit the release of growth hormone from the pituitary in mammals as well as inhibit the proliferation of human cancers through a...
Matches 151 - 200 out of 446 < 1 2 3 4 5 6 7 8 9 >