Patents and Patent Applications from University of Maryland


Match Document Document Title
9868217 All-elastomer 3-axis contact resistive tactile sensor arrays and micromilled manufacturing methods thereof  
At least one tactile sensor includes an insulating layer and a conductive layer formed on the surface of the insulating layer. The conductive layer defines at least one group of flexible...
US20180011249 FIBER-TO-WAVEGUIDE COUPLERS WITH ULTRA HIGH COUPLING EFFICIENCY AND INTEGRATED CHIP WAVEGUIDES INCLUDING THE SAME  
An easy-to-fabricate and highly efficient single-mode optical fiber-to-single-mode optical waveguide coupler having relatively large horizontal and vertical alignment tolerances between the fiber...
US20180011244 GENERATION OF ARBITRARY OPTICAL FILTERING FUNCTION USING COMPLEX BRAGG GRATINGS  
A waveguide Bragg grating includes a silicon substrate defining a length, a width and a depth and a silicon dioxide (SiO2) cladding over the silicon substrate and encasing a silicon nitride...
US20180010299 SUPER CLEAR CELLULOSE PAPER  
Wood fibers possess natural unique hierarchical and mesoporous structures that enable a variety of new applications beyond their traditional use. For the first time we dramatically modulate the...
9863886 Color changing polymer films for detecting chemical and biological targets  
A sensor system, and a method of detecting a target analyte, comprises a chemically functionalized block copolymer, and a target analyte. The block copolymer exhibits a color change in the visible...
US20180005647 MULTIPLE PITCH EXTRACTION BY STRENGTH CALCULATION FROM EXTREMA  
An apparatus includes a function module, a strength module, and a filter module. The function module compares an input signal, which has a component, to a first delayed version of the input signal...
9858531 Fault tolerant scalable modular quantum computer architecture with an enhanced control of multi-mode couplings between trapped ion qubits  
A modular quantum computer architecture is developed with a hierarchy of interactions that can scale to very large numbers of qubits. Local entangling quantum gates between qubit memories within a...
9855555 Generation and trapping of aqueous droplets in a microfluidic chip with an air continuous phase  
The invention relates to a method and system for generating droplets of an aqueous solution on a microfluidic chip with an air continuous phase. Specifically, the droplet generator according to...
9850473 Transglycosylation activity of glycosynthase mutants of an endo-beta-N-acetylglucosaminidase (endo-D) from Streptococcus pneumoniae  
The present invention provides for recombinant Endo-D and selected mutants that exhibit reduced hydrolysis activity and increased transglycosylation activity for the synthesis of glycoproteins...
US20170363632 Biomarker Kit for Metastatic Breast Cancer Prognosis and Uses Thereof  
Provided herein are kits for detecting and quantifying the level of a metastatic cancer biomarker(s) in a patient. The kits may contain a detection and quantifying means, such as, biomarker...
9845360 Chemoenzymatic glycoengineering of antibodies and Fc fragments thereof  
The present invention provides for recombinant Endo-S mutants that exhibit reduced hydrolysis activity and increased transglycosylation activity for the synthesis of glycoproteins wherein a...
US20170352061 OPTIMAL SOCIAL NETWORK AD ALLOCATION USING HYPERBOLIC EMBEDDING  
Various computational systems may benefit from improvement in determining optimal allocation. For example certain social network advertisement systems may benefit from the use of hyperbolic...
9833468 Methods for treating progeroid laminopathies using oligonucleotide analogues targeting human LMNA  
Provided are methods of treatment in subjects having progeroid diseases and related conditions which rely upon LMNA-targeted antisense oligonucleotides for reducing expression of one or more...
US20170342458 BIOMASS CONTAINMENT DEVICE  
A biomass containment device (BCD) and methods of measuring microbial growth or enzyme activity in the presence of insoluble substrates using the BCD is described. The BCD is compatible with...
US20170338522 INTERFACIAL LAYERS FOR SOLID-STATE BATTERIES AND METHODS OF MAKING SAME  
One or more interfacial layers in contact with a solid-state electrolyte and hybrid electrolyte materials. Interfacial layers comprise inorganic (e.g., metal oxides and soft inorganic materials)...
US20170336509 PROJECTILE POSITION MEASUREMENT USING NON-LINEAR CURVE FITTING  
An electronic home plate provides assistance to an umpire in determining whether a pitch results in a “strike” or a “ball.” The home plate is implemented with LEDs producing discrete pulses of...
US20170333522 EXPRESSION AND FUNCTION OF GPR64/ADGRG2 IN ENDOCRINE SYSTEMS AND METHODS TO TARGET IT THERAPEUTICALLY  
Provided herein are methods of treating hypercalcemia in a subject, comprising administering to the subject a therapeutically effective amount of a composition that decreases the expression level...
US20170333454 INHIBITORS OF NCCA-ATP CHANNELS FOR THERAPY  
Methods and compositions are provided that are utilized for treatment and/or prevention of intraventricular hemorrhage or progressive hemorrhagic necrosis (PHN), particularly following spinal cord...
US20170332468 LASER-DRIVEN HIGH REPETITION RATE SOURCE OF ULTRASHORT RELATIVISTIC ELECTRON BUNCHES  
A laser-plasma-based acceleration system includes a focusing element and a laser pulse emission directing a laser beam to the focusing element to such that laser pulses transform into a focused...
US20170327427 PHOSPHORUS EXTRACTION AND RECOVERY SYSTEM (PEARS)  
Separation methods and systems for converting high concentrations of animal wastes into nutrients and other useful products such as struvite and potassium struvite. Advantageously, the system and...
US20170326345 ADVANCED FUNCTIONAL BIOCOMPATIBLE FOAM USED AS A HEMOSTATIC AGENT FOR COMPRESSIBLE AND NON-COMPRESSIBLE ACUTE WOUNDS  
A sprayable polymeric foam hemostat for both compressible and non-compressible (intracavitary) acute wounds is disclosed. The foam comprises hydrophobically-modified polymers, such as hm-chitosan,...
US20170326171 ADVANCED FUNCTIONAL BIOCOMPATIBLE POLYMER PUTTY USED AS A HEMOSTATIC AGENT FOR TREATING DAMAGED TISSUE AND CELLS  
A hemostatic putty for treatment of a variety of wounds topographies, including but not limited to highly three dimensional wounds, for example gunshot wounds and impalements, is disclosed. The...
US20170326169 Advanced functional biocompatible polymeric matrix containing nano-compartments  
The present invention provides a novel biomaterial which is a hybrid, self-assembling biopolymeric networked film that is functionalized through hydrophobic interactions with vesicles loaded with...
9816990 Ultra-fast pathogen toxin detection assay based on microwave-accelerated metal-enhanced fluorescence  
The present invention provides for a system and method to detect low levels of the anthrax protective antigen (PA) exotoxin in biological fluids, wherein the system uses a metal-enhanced...
US20170322081 Tunable Near-Infrared Emitters and Methods  
The present invention relates to near-infrared quantum emitters, and in particular carbon nanostructures with chemically incorporated fluorescent defects, and methods of synthesizing near-infrared...
US20170321256 METHODS FOR DISTINGUISHING INFLAMMATORY BOWEL DISEASES USING MICROBIAL COMMUNITY SIGNATURES  
The inventive subject matter relates broadly to novel techniques for identification and comparative analysis of sequence features in metagenomic whole-genome shotgun (WGS) sequence data associated...
US20170319655 MUC1 DECOY PEPTIDES FOR TREATMENT AND PREVENTION OF BACTERIAL INFECTIONS  
Pseudomonas aeruginosa flagellin protein recruits the mammalian host sialidase enzyme neuraminidase-1 (NEU1) to remove sialic acid residues from the extracellular domain of the mammalian...
PP28595 Apple tree named ‘CP 101’  
A new and distinctive variety of Malus domestica apple tree, named ‘CP 101’ that is distinguished by its attractive fruit color and flavor, early harvest season that is different than its seed...
9810637 Plasmonic electricity  
The present invention relates to detection systems and methods that detect fluorescence, luminescence, chemiluminescence or phosphorescence signatures in the form of an electrical signal conducted...
9808472 Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies  
Described herein are methods and compositions for the treatment of prostate cancer in a subject in need thereof. The prostate cancer may be a castration resistant and an androgen receptor...
US20170317382 BATTERY MADE FROM A SINGLE MATERIAL  
A solid-state lithium-ion battery may include an anode, a solid electrolyte layer of material, and a cathode. Each consist of the solid electrolyte material and are interspersed with a current...
9804068 Particle separation and concentration using spiral inertial filtration  
A spiral inertial filtration device is capable of high-throughput (1 mL/min), high-purity particle separation while concentrating recovered target particles by more than an order of magnitude....
9803216 Genetically-engineered newcastle disease virus as an oncolytic agent, and methods of using same  
Recombinant strains of avian paramyxovirus (APMV), such as Newcastle disease virus (NDV), are provided. Also provided are compositions comprising them, and methods of using them to lyse tumor...
9802988 Engineered type IV pilin of Clostridium difficile  
The present invention relates to engineered Clostridium difficile type IV pilin (tfp) genes, type IV pilin proteins which can serve as a diagnostic marker for identification of patients infected...
9801955 Methods and compositions for detecting drusen and predicting age-related macular degeneration  
Labels and methods are provided for detecting deposits, including drusen, sub-retinal deposits, basal laminar and linear deposits, and the like. The labels can detect the presence, progression, or...
US20170307593 METHODS FOR TREATING NEURAL CELL SWELLING  
A composition comprising a novel Ca2+-activated, [ATP]i-sensitive nonspecific cation (NCCa-ATP) channel is described. The channel is found in mammalian neural cells and exhibits a different...
US20170304410 TREATMENT OF CANCER AND INHIBITION OF METASTASIS USING HEMOGLOBIN BETA SUBUNIT  
The beta 2 subunit of mouse hemoglobin (HBB2) has been identified as soluble factor from mouse lungs that exhibits cytostatic/cytotoxic activity against neuroblastoma lung micrometastases. The...
US20170303958 SELF-SEALING CANNULA  
The present invention discloses a self-sealing cannula and methods of its use. The self-sealing cannula can be minimally invasively placed into the heart for drawing and/or returning blood with a...
9795471 Polymer-tissue hybrid biomaterials and methods of making and using same  
Provided are hybrid biomaterials comprising one or more layers of cross-linked poly(propylene fumarate) and/or cross-linked copolymer comprising a plurality of cross-linked propylene fumarate...
US20170299513 TUNING OF METAL ENHANCED EMISSIONS OF LONG-LIVED LUMINESCENT COMPOUNDS  
The present invention provides for the surface plasmon-enhancement of long lived luminescent compounds, thereby providing for methods and systems having enhanced and controllable rates of the...
US20170299477 Aerosol Collection System and Method  
The present invention relates to systems and methods for collecting and analyzing bioaerosols, including exhaled breath aerosol from a subject. The collection system comprises an inlet portion...
US20170298108 COMPOSITIONS COMPRISING GRIM-19 THERAPEUTICS AND METHODS OF USE  
The present invention provides nucleic acids encoding a fusion protein comprising a nucleotide sequence encoding GRIM-19 or a biologically active fragment or derivative thereof and a nucleotide...
US20170297029 INTEGRATED THERMOPLASTIC CHIP FOR RAPID PCR AND HRMA  
The present invention relates to a microfluidic system including a temperature controller and a thermoplastic microfluidic chip that enables rapid PCR in a PCR chamber of the microfluidic chip....
US20170296555 TARGETING NCCA-ATP CHANNEL FOR ORGAN PROTECTION FOLLOWING ISCHEMIC EPISODE  
The present invention concerns protection of an organ or tissue outside of the central nervous system following an ischemic episode. In particular aspects, the invention concerns organ...
US20170295014 METHOD AND APPARATUS FOR AUTHENTICATING DEVICE AND FOR SENDING/RECEIVING ENCRYPTED INFORMATION  
Methods and apparatuses for authenticating communication devices and securely transmitting and/or receiving encrypted voice and data information. A biometric scanner, for example a fingerprint...
US20170291930 Histatin-5 Based Synthetic Peptides and Uses Thereof  
Provided herein are synthetic peptides or synthetic fragments thereof based on a Histatin-5 peptide, for example with a sequence DSHAKRHHGYKRKFHEKHHSHRGY (SEQ ID NO: 1). The synthetic peptides or...
9784682 Fluorescence microscope in microwave cavity  
The present invention relates to an optical imaging system communicatively connected to a microwave energy producing source wherein the combination provides for increases in chemical reaction...
US20170283486 STABLE IMMUNOGEN BASED ON INNER DOMAIN OF HIV-1 GP120 FOR INDUCING IMMUNITY AGAINST HIV  
Stable immunogens comprising portions of the inner domain (ID) of the Human Immunodeficiency Virus (HIV-1) gp120 protein are provided. These ID immunogens selectively present the gp120 C1/C2...
9775929 Solution blow spun polymer fibers, polymer blends therefor and methods and use thereof  
Compositions comprising biomedical polymers, and in particular unique blends of poly(lactic-co-glycolic acid) (PLGA) and poly(ethylene glycol) (PEG) are provided. Methods of forming polymer fibers...
US20170278431 Central Pressurized Cadaver Model  
Provided are methods for creating a pressurized cadaver model used for surgical procedure training. In the method the internal jugular veins, common carotid arteries, brachial arteries,...