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US20120122723 |
METHODS OF DETECTING AUTOANTIBODIES FOR DIAGNOSING AND CHARACTERIZING DISORDERS
Methods for detecting and/or quantitating levels of autoantibodies in subjects are provided. Methods for diagnosing and/or characterizing a disorder associated with autoantibody production are...
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8178045 |
Interchangeable preconcentrator connector assembly
An interchangeable preconcentrator assembly comprises an outer housing and an inner housing defining a chamber. A biased urging member is held at least partially within the outer housing and...
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8168438 |
Chemical sensors for detecting hydrogen and methods of use
The presently-disclosed subject matter provides sensors and methods for detecting hydrogen by determining the conductivity of a chemiresistant film upon exposure to hydrogen, including for example...
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US20120101747 |
DETECTION AND IMAGING OF TURBULENCE IN A FLUID
A system and method detect turbulence in a fluid by processing image data to isolate and detect fluctuations in a frequency range indicative of turbulence. By making use of a Fourier or other...
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8161916 |
Decubitus ulcer prevention garment for dogs
Decubitus ulcer prevention garments for a dog are provided that include a fluid-filled bladder. The garments can include an inner layer that contacts and interacts with the body of the dog; an...
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US20120083440 |
METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH
Bone targeted compounds and methods are provided. Compounds can include a Bone Targeting Portion (RT), having an affinity for bone; a Bone Active Portion (RA) for interacting with and affecting...
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8142806 |
Methods and compositions for controlled delivery of phytochemical agents
The presently-disclosed subject matter provides compositions and methods for treating a cancer by providing a composition comprising a biocompatible polymeric matrix incorporating an effective...
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8142764 |
Synthetic biofilm-inhibiting peptides
The present invention provides streptococcal SspB Adherence Region (BAR) peptides consisting of Formula I: R18-R1- R2-Val-R3-R4-Leu-Leu-R5-R6-R7-Ile-R8-R9-Lys-R10-R19 , wherein R2, is 1-3 Lys...
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8132611 |
Metallic nanostructures self-assembly, and testing methods
The invention provides method for metallic nanonstructures self-assembly methods and materials testing. Preferred embodiment methods permit for the formation of individual nanostructures and arrays...
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US20120059599 |
HYBRID FRAGMENT-LIGAND MODELING FOR CLASSIFYING CHEMICAL COMPOUNDS
A system and method generate a structure activity relationship model to determine whether unknown chemical compounds are of a desired classification where the structure activity relationship model...
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US20120059395 |
ENDOSCOPIC CLOSURE DEVICE
An endoscopic closure device comprises: a coupling member; a helical needle mounted to the coupling member and carrying a suture; and a plurality of grasping needles, each of said plurality of...
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US20120058933 |
SYNTHETIC PEPTIDES AND PEPTIDE MIMETICS
The present invention provides Parotid Secretory Protein peptides, nucleic acids encoding the peptides, and methods of using the peptides, and methods of screening GL13 mimetics.
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US20120053692 |
COMPOSITIONS AND METHODS FOR TREATING BONE DEFECTS
A bone graft composition includes a biologically-resorbable cement and a plurality of processed bone particles, where each of the bone particles have a shape configured to interconnect with...
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US20120028272 |
DEVICE AND METHODS FOR ISOLATING CELLS
The invention provides a device and methods for separating and isolating cells.
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US20120028124 |
ANODE MATERIALS FOR LITHIUM-ION BATTERIES
An anode material for lithium-ion batteries is provided that comprises an elongated core structure capable of forming an alloy with lithium; and a plurality of nanostructures placed on a surface of...
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US20120027955 |
REACTOR AND METHOD FOR PRODUCTION OF NANOSTRUCTURES
A reactor and method for production of nanostructures produces, for example, metal oxide nanowires or nanoparticles. The reactor includes a metal powder delivery system wherein the metal powder...
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US20120009606 |
PEPTIDE BIOMARKERS PREDICTIVE OF RENAL FUNCTION DECLINE AND KIDNEY DISEASE
The presently-disclosed subject matter provides methods for diagnosing a kidney disease, or the risk thereof, in a subject. The methods comprise determining an amount of at least one peptide...
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8088385 |
PFKB3 inhibitor for the treatment of a proliferative cancer
A methods and compounds for inhibiting 6-phosphofructo-2-kinase /fructose-2,6-bisphosphatase 3 (PFKFB3) are described. Also described are methods of inhibiting cell proliferation, treating cancer,...
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8088341 |
Analyte collection devices and methods
An aspect of the invention is directed to an analyte collection device of the type that includes at least one plate for storing the analyte and a heating element for heating the at least one plate....
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US20110319351 |
TREATING CANCER WITH CARDIAC GLYCOSIDES
The invention provides methods to treat cancer with cardiac glycosides.
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US20110318761 |
METHODS AND KITS FOR PREDICTING A RESPONSE TO AN ERYTHROPOIETIC AGENT
Methods for predicting a response to an erythropoietic agent in a subject include providing a biological sample from the subject, and determining an amount in the sample of at least one peptide...
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US20110311442 |
DIRECT CELLULAR ENERGY DELIVERY SYSTEM
A lipid vesicle comprising a phospholipid which is a stable vesicle former and at least one unstable vesicle forming member, wherein the unstable vesicle forming member is selected from the group...
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8076096 |
Alteration of cell membrane with FasL
Methods and compositions are provided for the persistent modification of cell membranes with exogenous proteins so as to alter the function of the cell to achieve effects similar to those of gene...
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US20110301860 |
USING DIFFERENTIAL SCANNING CALORIMETRY (DSC) FOR DETECTION OF INFLAMMATORY DISEASE
Disclosed herein in various embodiments are systems and methods for categorizing biological fluids obtained from subjects into one or more disease or treatment categories. Embodiments of the...
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8073226 |
Automatic detection and monitoring of nodules and shaped targets in image data
A method for detecting a nodule in image data including the steps of segmenting scanning information from an image slice to isolate lung tissue from other structures, resulting in segmented image...
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8071575 |
Methods and compounds for the targeted delivery of agents to bone for interaction therewith
Bone targeted compounds and methods are provided. Compounds can include a Bone Targeting Portion (RT), having an affinity for bone; a Bone Active Portion (RA) for interacting with and affecting...
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US20110295027 |
Catalytic Isomerisation of Fatty Acid Esters
Catalytic isomerisation of fatty acid esters to form branched fatty acid esters comprises the steps of contacting a feedstock having at least one fatty acid ester with a catalyst and isolating from...
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8067160 |
Genetic markers of schizophrenia
The invention includes method of determining if a subject has a genetic predisposition to clinically diagnosed schizophrenia (SZ), schizotypal personality disorder (SPD), and/or schizoaffective...
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US20110283957 |
DECUBITUS ULCER PREVENTION GARMENT FOR DOGS
Decubitus ulcer prevention garments for a dog are provided that include a fluid-filled bladder. The garments can include an inner layer that contacts and interacts with the body of the dog; an...
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US20110257211 |
Small-Molecule Choline Kinase Inhibitors as Anti-Cancer Therapeutics
Small molecule choline kinase inhibitors having the following formula: are provided herein. Also provided herein are pharmaceutical compositions containing Formula I compounds, together with...
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8041141 |
Method and software for shape representation with curve skeletons
Embodiments of the invention utilize a variational framework for computing curve skeletons (CS) of objects whose cross section is not necessary tubular. Embodiments utilize an energy function,...
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8039227 |
Peptide biomarkers predictive of renal function decline and kidney disease
Methods for diagnosing a kidney disease, or the risk thereof, in a subject are provided. The methods comprise determining an amount of at least one peptide biomarker disclosed herein in a...
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US20110243898 |
SOMATIC CELL-DERIVED PLURIPOTENT CELLS AND METHODS OF USE THEREFOR
Provided are methods for producing a reprogrammed fibroblast. The methods can include growing a plurality of fibroblasts in monolayer culture to confluency; and disrupting the monolayer culture to...
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8029784 |
Method for the diagnosis and prognosis of malignant diseases
Methods for the treatment of tumors and cancer by exploiting the surface expression of the usually nuclear-localized protein, nucleolin.
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US20110224091 |
METHOD AND DEVICE FOR DETECTING CELLULAR TARGETS IN BODILY SOURCES USING CARBON NANOTUBE THIN FILM
A device and method detect cellular targets in a bodily source by utilizing a biofunctional pad comprised of a thin film of carbon nanotubes (CNT's). When antibodies are absorbed by the CNT's,...
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8017582 |
Immunostimulatory compositions and methods
The invention provides conjugates comprising an immune co-stimulatory polypeptide and an antigen or infectious agent. The conjugates are useful for generating or enhancing an immune response...
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US20110217719 |
METHODS AND KITS FOR DIAGNOSING OBSTRUCTIVE SLEEP APNEA
The presently-disclosed subject matter provides methods and kits for diagnosing obstructive sleep apnea (OSA) in a subject, such as a human child, wherein a biological sample is provided from the...
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US20110214482 |
LARGE VOLUME ANALYTE PRECONCENTRATOR
A large volume preconcentrator device for concentrating analytes. A housing accepts an analyte vapor flow, and a plurality of collection surfaces are disposed within the housing. A selectively...
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8014561 |
Virtual fly over of complex tubular anatomical structures
An embodiment of the invention is method, which can be implemented in software, firmware, hardware, etc., for virtual fly over inspection of complex anatomical tubular structures. In a preferred...
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US20110213019 |
Compositions and Methods for Treating Cancer, Inhibiting Proliferation, and Inducing Cell Death
Quadruplex-forming guanine-rich nucleic acid sequences are useful in compositions and methods for inhibiting cellular growth and proliferation and inducing cell death. Compositions for treating a...
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US20110209604 |
COMPOSITE ARMOR PANEL
A composite armor panels is comprised of a first layer, composed of a matrix of an elastomeric material and a crushed aggregate material, and a second backing layer. One or more geogrids can be...
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7988839 |
Capillary electrophoresis systems and methods
An embodiment of the invention is directed to a capillary electrophoresis apparatus comprising a plurality of separation micro-channels. A sample loading channel communicates with each of the...
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US20110178020 |
METHODS AND COMPOSITIONS FOR INHIBITION OF NEUTROPHIL EXOCYTOSIS
Isolated fusion polypeptides are provided that are comprised of a cell-penetrating polypeptide and a SNARE polypeptide aptamer. Further provided are methods for inhibiting neutrophil granule...
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US20110166114 |
METHOD FOR TREATING SNORING AND SLEEP APNEA WITH LEUKOTRIENE ANTAGONISTS
A method of treating snoring and/or sleep apnea comprising administering to a patient in need of such treatment a therapeutically effective amount of a leukotriene receptor antagonist.
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US20110159016 |
HEMOGLOBIN-BASED METHODS FOR PROPHYLAXIS, DIAGNOSIS AND/OR TREATMENT OF RETINAL DISORDERS
The presently disclosed subject matter provides methods of diagnosing retinal disorders in subjects by measuring hemoglobin and modified hemoglobin in the subjects. The presently disclosed subject...
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US20110155575 |
CAPILLARY ELECTROPHORESIS SYSTEMS AND METHODS
An embodiment of the invention is directed to a capillary electrophoresis apparatus comprising a plurality of separation micro-channels. A sample loading channel communicates with each of the...
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7964557 |
Inhibition of wet type age related macular degeneration (AMD) by adiponectin or acrp 30
The present invention provides new methods of treating wet type of age related macular degeneration by administering adiponectin (APN) or a functional fragment derived therefrom. One of the...
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US20110143341 |
Microsatellite Markers of Schizophrenia
The invention includes methods of determining if a subject is at risk for developing schizophrenia (SZ).
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US20110130457 |
Wax-Based Emulsion for the Treatment of Dry Eye Conditions
Disclosed herein is a wax-based emulsion for the treatment of dry eye conditions by reducing the evaporation rate of saline and increasing the viscosity of the tear film. The composition of the...
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7948421 |
Frequency counter based analog-to-digital converter
An analog-to-digital converter (ADC) is provided. The ADC includes a variable oscillator, a frequency divider, a clock circuit, and a counter. The variable oscillator is coupled to a sensor and...
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