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Patents and Patent Applications from University of Kansas


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8785411 HIV DNA vaccine methods of use  
The present invention is directed to a DNA vaccine for immunization against HIV. The invention comprises a DNA molecule that has a sequence encoding a plurality of viral proteins capable of...
US20140200678 BIOMATERIALS WITH MICROSPHERE GRADIENTS AND CORE AND SHELL MICROSPHERES  
Methods can prepare tissue engineering scaffolds that include a plurality of biocompatible core/shell microspheres linked together to form a three-dimensional matrix. The matrix can include a...
US20140196894 FLUORESCENT TAGS FOR DETECTION OF SWELLABLE POLYMERS  
The invention is directed to stable crosslinked swellable fluorescently tagged polymeric microparticles, methods for making same, and their various uses. A particularly important use is as an...
8777157 Tethered hovering platform  
The design and refinement of a tethered hovering platform into a feasible working system is presented. To determine a starting point for the design, a detailed historical search was conducted to...
8765803 Rab7 GTPase inhibitors and related methods of treatment  
This invention relates to compounds and their use as inhibitors or activators of Rab7 GTPase to treat or prevent the onset of Rab 7 GTPase-associated disorders such as neuropathies, cancer,...
8765140 DNA vaccine compositions with HIV/SIV gene modifications  
The present invention is directed to a DNA vaccine for immunization against HIV. The invention comprises a DNA molecule that has a sequence encoding a plurality of viral proteins capable of...
US20140163528 MANEUVERABLE NASOENTERIC FEEDING TUBE  
A maneuverable feeding tube system can include: a feeding tube having an internal lumen and distal opening; a maneuverable tube having a flexible distal end being located within the internal lumen...
US20140162912 SWELLABLE POLYMER WITH CATIONIC SITES  
The invention is directed to long lasting crosslinked water-soluble swellable polymers, methods for making same, and their uses. More particularly, the invention relates to a composition comprising...
8747563 Method and apparatus for anti-fouling an anemometer  
An apparatus and method for adaptive materials arranged in a variety of orientations and with a wide range of attachment configurations to induce structural vibrations at extremely high...
US20140148915 GENERATING CK19-POSITIVE CELLS WITH HAIR-LIKE STRUCTURES FROM WHARTONS JELLY  
A method of differentiating cells into CK19-positive cells capable of producing hair follicle-like and hair structure-like can include: providing a tissue scaffold; seeding cells into the scaffold,...
US20140144628 CROSSLINKING OF SWELLABLE POLYMER WITH PEI  
The invention is directed to stable and labile crosslinked water swellable polymeric microparticles that can be further gelled, methods for making same, and their various uses in the hygiene and...
8735391 Synthesis of functionalized octahydro-isoquinolin-1-one-8-carboxamides, octahydro-isoquinolin-1-one-8-carboxylic esters and analogs, and therapeutic methods  
A functionalized polycyclic compound can have a structure of Formula 1 or salt, prodrug, analog, or derivative thereof, which compound can be prepared by providing a diene; reacting the diene with...
8735154 Templated islet cells and small islet cell clusters for diabetes treatment  
A scaffold having islet cells or small islet cell clusters attached thereto in a multilayer, and a micro-mold having divots for culturing islets, wherein islet formation is influenced by the shape...
8734367 Method and apparatus for measuring non-nutritive suck pattern stability  
Method and apparatus are provided for generating an index associated with non-nutritive suck pattern stability. An example apparatus can include an STI generator configured to generate a plurality...
8728486 Toll-like receptor-7 and -8 modulatory 1H imidazoquinoline derived compounds  
The present disclosure provides novel imidazoquinoline derived compounds, derivatives thereof, analogues thereof, and pharmaceutically acceptable salts thereof, and methods of making and using such...
US20140135484 Metal Abstraction Peptide (MAP) Tag and Associated Methods  
Compositions comprising a tripeptide having the sequence XC1C2; wherein X is any amino acid such that XC1C2 is capable of binding a metal in a square planar orientation or square pyramidal...
US20140131043 SWELLABLE POLYMER WITH ANIONIC SITES  
The invention is directed to stable crosslinked water-soluble swellable polymers and methods for making same. More particularly, the invention relates to a composition comprising expandable...
8715983 Hudrogel network comprising thermally gelling polysaccharide or protein gel encapsulating living cells  
The present invention is directed to a hydrogel network comprised of a physically cross-linked polymer and a chemically cross-linked polymer or physically entangled copolymer containing living...
8709997 Prevention and treatment of osteoarthritis  
Subjects lacking Nfat1 display osteoarthritis in weight-bearing joints. Osteoarthritic changes associated with Nfat1 deficiency are characterized by articular cartilage degradation, articular...
8691736 Swellable polymer with cationic sites  
The invention is directed to long lasting crosslinked water-soluble swellable polymers, methods for making same, and their uses. More particularly, the invention relates to a composition comprising...
8685966 GRP94 inhibitors  
The present disclosure provides a series of compounds which exhibit isoform selective inhibition of GRP94, a homologue of Hsp90 that is localized to the endoplasmic recticulum. Through GRP94...
US20140088144 INHIBITING MICROBIAL INFECTIONS  
A method of inhibiting a microbial infection can include: providing a compound of the invention or prodrugs or pharmaceutically acceptable salts thereof; and administering the compound to a subject...
US20140081050 SINGLE SOLVENT GAS EXPANDED HYDROFORMYLATION PROCESS  
Allyl alcohol, particularly from biobased sources such as glycerol, is hydroformylated to products including 4-hydroxybutyraldehyde and 4-hydroxy-2-methylpropionaldehyde by forming a homogeneous...
8673584 Inhibitor scaffold for the inhibition of the enzyme phosphoenolpyruvate carboxykinase  
A PEPCK inhibitor can include identifying a molecule that has a size capable of fitting into and interacting with the PEPCK binding site and at least one of the following: (a) a first terminal...
8669214 Swellable polymer with anionic sites  
The invention is directed to stable crosslinked water-soluble swellable polymers and methods for making same. More particularly, the invention relates to a composition comprising expandable...
8669107 Method of preparing a tissue engineering scaffold comprising a plurality of microspheres linked together  
Methods can prepare tissue engineering scaffolds that include a plurality of biocompatible microspheres linked together to form a three-dimensional matrix. The matrix can include a plurality of...
US20140058593 LOW-ALTITUDE ALTIMETER AND METHOD  
A low-altitude altimeter (10) and a method of determining low altitudes for unmanned aerial vehicles (24). The altimeter includes at least two illuminators (12, 14), at least one sensor (16), and a...
8653975 Radio-frequency identification device with foam substrate  
The present invention encompasses an antenna (12) for use with a radio-frequency identification transponder (10) that performs optimally in free space and near optimally when near a conductive...
US20140046231 MEDICAL DEVICE FOR THERAPEUTIC STIMULATION OF THE VESTIBULAR SYSTEM  
A method for providing vestibular stimulation includes: providing an infant in a vestibular stimulation device; associating sensors to the infant; moving the vestibular stimulation device to...
US20140045851 MORPHOLINES AS SELECTIVE INHIBITORS OF CYTOCHROME P450 2A13  
A method of inhibiting formation of cancerous metabolites, of inhibiting cytochrome P450 2A13 from forming carcinogen metabolites, and/or inhibiting formation of cancerous lung cells in a subject...
US20140037626 Metal Abstraction Peptide With Release of Metal  
Compositions comprising peptides that are capable of binding a metal in a square planar orientation, a square pyramidal orientation, or both, are disclosed. Such compositions can be used for...
8639116 Digital subcarrier optical network utilizing digital subcarrier cross-connects with increased energy efficiency  
The present invention provides reduced power dissipation and other benefits at the optical transport network layer by utilizing a digital subcarrier optical network comprising multiple digital...
8637468 Synthetic cholesterylamine-linker derivatives for agent delivery into cells  
Synthetic cholesterylamine-linkers can include derivatives of cholesterol, cholesteryl, or sitosteryl coupled through the linker to an agent for delivery into cells. The cholesterylamines are...
US20140008447 MICROSTRIP ANTENNA FOR RFID DEVICE HAVING BOTH FAR-FIELD AND NEAR-FIELD FUNCTIONALITY  
Microstrip patch antenna (46), feed structure (48), and matching circuit (50) designs for an RFID tag (10). A balanced feed design using balanced feeds coupled by a shorting stub (56) to create a...
US20140005132 CONTRACEPTIVE AGENTS  
The invention provides compounds of formula I, II, III, or IV: wherein R1 to R11, X, and Y have any of the values defined in the specification. The compounds inhibit Na, K-ATPase α4 and are useful ...
US20130341281 Surface Modified Ceramic Filter  
A porous ceramic filter having one or more coatings of elemental or compounds of iron, manganese, aluminum, titanium, or mixtures thereof deposited on the surface of the pores.
8609637 Prodrugs of 6-cyclohexyl-1-hydroxy-4-methylpyridin-2-(1H)-one and derivatives thereof  
A prodrug can have a structure of Formula 10 or derivative thereof or stereoisomer thereof or pharmaceutically acceptable salt thereof. The prodrug can be included in a pharmaceutical composition...
8608479 Systems and methods for facilitating gait training  
In one embodiment a gait training system includes a patient interface adapted to attach to a patient's thigh, the patient interface defining a channel, a cord that passes through the channel of the...
US20130331018 Laboratory Fume Hood System Having Recessed Heat Exchanger System  
A laboratory fume hood system for cooling at least one laboratory device located in an interior work area comprises a heat exchanger system having a heat exchanger in thermal communication with a...
US20130330314 Metal Abstraction Peptide With Superoxide Dismutase Activity  
Compositions comprising peptides that are capable of binding a metal are disclosed. Such compositions can be used for binding metal in a variety of contexts and environments. In various...
US20130319410 INHALATION DEVICE, SYSTEMS, AND METHODS FOR ADMINISTERING POWDERED MEDICAMENTS TO MECHANICALLY VENTILATED SUBJECTS  
Inhalation devices, systems, and methods for the administration of powdered medicaments to mechanically ventilated subjects are provided. In one embodiment, an inhalation device adaptively...
8598339 Withanolide isolated from Physalis longifolia and analogs and methods of use thereof  
The present invention features novel withanolides, as well as analogs and salts thereof, for use in the treatment of proliferative disease, cardiovascular disease, neurodegenerative disease and...
8598165 Morpholines as selective inhibitors of cytochrome P450 2A13  
A method of inhibiting formation of cancerous metabolites, of inhibiting cytochrome P450 2A13 from forming carcinogen metabolites, and/or inhibiting formation of cancerous lung cells in a subject...
US20130316392 IN VITRO TUMOR IN DISH KIT AND METHOD  
This invention is a method and kit for preparing a Tumor in Dish model for use in screening anti-cancer agents and analyzing cancer growth and development.
8583296 Low-altitude altimeter and method  
A low-altitude altimeter (10) and a method of determining low altitudes for unmanned aerial vehicles (24). The altimeter includes at least two illuminators (12,14), at least one sensor (16), and a...
US20130296190 PREDICTION OF SPONTANEOUS PRETERM BIRTH BY MEASURING CELL FREE NUCLEIC ACIDS IN MATERNAL BLOOD  
A nucleic acid normalization kit can include a nucleic acid having a normalization sequence including or complementary to one or more of SEQ ID NOs: 1-4 and 301-303 or unique segment thereof, the...
8568747 Enalapril compositions  
Provided herein are stable enalapril powder compositions for oral liquid formulation. Also provided herein are methods of using enalapril oral liquid formulations for the treatment of certain...
US20130280720 TISSUE BIOMARKERS FOR INDICATION OF PROGRESSION FROM BARRETT'S ESOPHAGUS TO ESOPHAGEAL ADENOCARCINOMA  
A method of diagnosing progression from Barrett's esophagus toward esophageal dysplasia can include: obtaining miRNA from a test subject having Barrett's esophagus; assaying for miRNA biomarker...
8564439 Microstrip antenna for RFID device  
Microstrip patch antenna (46), feed structure (48), and matching circuit (50) designs for an RFID tag (10). A balanced feed design using balanced feeds coupled by a shorting stub (56) to create a...
US20130264542 Multiwall Carbon Nanotube Opto-Electronic Devices  
A high-sensitivity detector for opto-electronic detection using multiwall carbon nanotubes (MWCNTs) is provided. More specifically, multiwall carbon nanotube films demonstrate an infrared...
Matches 1 - 50 out of 440 1 2 3 4 5 6 7 8 9 >