Patents and Patent Applications from University of Florida


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US20170356009 GENOME-MODIFIED RECOMBINANT ADENO-ASSOCIATED VIRUS VECTORS  
Provided herein are recombinant adeno-associated virus (rAAV) nucleic acid vectors that comprise one or more modifications within at least one inverted terminal repeat (ITR) region. Exemplary...
US20170352444 ROTATING RADIATION SHUTTER COLLIMATOR  
A shutter for controlling radiation exposure includes a rotatable member. The rotatable member is rotatable between an open position and a closed position. The rotatable member includes a...
US20170348387 AAV-MEDIATED GENE THERAPY FOR NPHP5 LCA-CILIOPATHY  
Described herein are methods of preventing, arresting progression of or ameliorating vision loss and other conditions associated with Leber congenital amaurosis (LCA) in a subject. The methods...
US20170347602 OAT VARIETY FL0720  
The invention provides oat seed and plants of the oat variety FL0720 that have resistance to crown rust. The invention further provides seed and plants of the oat variety FL0720 and progeny...
9836849 Method for the autonomous image segmentation of flow systems  
Disclosed herein is a method that comprises obtaining an image of a network section through which flow occurs; where the flow is selected from a group consisting of fluid, electrons, protons,...
9836667 System and method for analyzing random patterns  
Disclosed herein is a system and a method for analyzing apparent random pathways, patterns, networks, or a series of events and characterizing these apparent random pathways, patterns, networks,...
9833612 Apparatuses and methods for securing deep brain stimulation leads  
Various examples are provided for securing deep brain stimulation (DBS) leads. In one example, among others, a DBS cap for securing a DBS lead includes a base ring adapted to be mounted within a...
9833200 Low IF architectures for noncontact vital sign detection  
Various examples of methods and systems are provided for vibrational frequency detection (e.g., noncontact vital sign detection) using digitally assisted low intermediate frequency (IF)...
US20170343488 THREE-DIMENSIONAL IMAGE RECONSTRUCTION USING TRANSMISSION AND SCATTER RADIOGRAPHY METHODS  
A method for image reconstruction includes irradiating an object with a beam of radiation from a radiation source, measuring an attenuated portion of the beam, estimating a density of the object,...
9829484 Use of anoctamin as a biomarker for radiation biodosimetry  
In one embodiment, the present invention pertains to the use of anoctamin as a biomarker for determining radiation dosimetery. In certain embodiments, the present invention relates to the use of...
9829452 Corrosion detection in structural tendons  
Various examples are provided for corrosion detection in structural tendons. In one example, among others, a method includes injecting current through a portion of a tendon assembly including a...
US20170333628 Devices and Methods for Minimizing Infusion of Air into an Intravenous Fluid Line from an Intravenous Fluid Bag by a Pressure Infusion Cuff  
The problem of infusing air into IV tubing and into a patient from a IV fluid bag inside a pressure infusion cuff is solved by collar embodiments that inhibit the air from being forced into the IV...
9821013 Compositions and methods for induction and modulation of angiogenesis and methods and assays for identifying angiogenesis modulators  
The present disclosure provides methods and compositions, including a placental extract, for inducing and/or modulating angiogenesis; methods of identifying modulators of angiogenesis, and assays...
US20170330657 NANOCOMPOSITE MAGNETIC MATERIALS FOR MAGNETIC DEVICES AND SYSTEMS  
Nanocomposite magnetic materials, methods of manufacturing nanocomposite magnetic materials, and magnetic devices and systems using these nanocomposite magnetic materials are described. A...
US20170327875 Sensitive and Rapid Method for Candidatus Liberibacter Species Detection  
DNA amplification methods using novel primers obtained from the novel genes hyvI and hyvII from the Candidatus Liberibacter asiaticus genome are useful for detecting Ca. L. species in plants and...
US20170326257 SATIATION PEPTIDES FOR WEIGHT LOSS AND ALTERED TASTE SENSITIVITY  
The present application provides methods and compositions for AAV-mediated delivery of PYY and Glucagon-like Peptide 1 or an analog thereof (e.g., Exendin-4) to a subject (e.g., the saliva of a...
9820369 Method and apparatus for providing high control authority atmospheric plasma  
Embodiments of the invention relate to a method and apparatus for providing high thrust density plasma, and/or high control authority plasma. In specific embodiments, such high thrust density,...
9818514 Nanocomposite magnetic materials for magnetic devices and systems  
Nanocomposite magnetic materials, methods of manufacturing nanocomposite magnetic materials, and magnetic devices and systems using these nanocomposite magnetic materials are described. A...
9816108 rAAV-guanylate cyclase compositions and methods for treating lebers congenital amaurosis-1 (LCA1)  
Disclosed are viral vector compositions comprising polynucleotide sequences that express one or more biologically-active mammalian guanylate cyclase proteins. Also disclosed are methods for their...
9815852 Macrocyclic compounds and methods of treatment  
The instant invention describes macrocyclic compounds having therapeutic activity, and methods of treating disorders such as cancer, tumors and cell proliferation related disorders.
9815051 Preparation of trihalide anion exchange resins  
A method of preparing a trihalide resin, where a trihalide ion solution is contacted with a styrene divinylbenzene polymer resin having polymer bonded -ER3+ X− groups where E is N, P, or As, R is...
US20170321306 RADIATION SHIELDING AND MITIGATING ALLOYS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME  
Embodiments of the present disclosure include compositions that include magnesium and gadolinium or magnesium and one or more metals.
US20170320018 CONTINUOUS ELECTROKINETIC DEWATERING OF PHOSPHATIC CLAY SUSPENSIONS  
Various methods and systems are provided for electrokinetic dewatering of suspensions such as, e.g., phosphatic clay. In one example, among others, a system for continuous dewatering includes a...
9810698 Neural proteins as biomarkers for nervous system injury and other neural disorders  
The present invention identifies biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree...
US20170317678 OVERLAY ARCHITECTURE FOR PROGRAMMING FPGAS  
An overlay architecture and an associated method that uses datapath merging to provide minimal-overhead support for multiple source netlists, and optionally provides an adjustable amount of...
9801829 Methods and systems of making nanostructures  
In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in one aspect, relate to methods of making...
9801731 Spinal implant and methods of manufacture thereof  
Disclosed herein is an intervertebral disc prosthesis comprising a first cantilever arm; the first cantilever arm comprising a shaft that is affixed to a disc; a second cantilever arm that...
US20170306368 METHODS FOR THAXTOMIN PRODUCTION AND MODIFIED STREPTOMYCES WITH INCREASED THAXTOMIN PRODUCTION  
In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in some aspects, relate to genetically modified...
US20170304797 SOLAR THERMOCHEMICAL REACTOR, METHODS OF MANUFACTURE AND USE THEREOF AND THERMOGRAVIMETER  
Disclosed herein is a solar thermochemical reactor comprising an outer member, an inner member disposed within an outer member, wherein the outer member surrounds the inner member and wherein the...
US20170304794 SOLAR THERMOCHEMICAL REACTOR AND METHODS OF MANUFACTURE AND USE THEREOF  
Disclosed herein is a solar reactor comprising a reactor member; an aperture for receiving solar radiation, the aperture being disposed in a plane on a wall of the reactor member, where the plane...
9800052 Method and apparatus for power management using distributed generation  
Embodiments relate to a method and system for power demand shaping (PDS) so as to manage power generation and use. Specific embodiments relate to data center power demand shaping to achieve...
9795427 Articles comprising reversibly attached screws comprising a biodegradable composition, methods of manufacture thereof and uses thereof  
Disclosed herein is an article comprising a first screw and a second screw, the first screw being reversibly attached to the second screw such that a longitudinal axis of the first screw coincides...
US20170298370 Viral Based Transient-Expression Vector System That Allows Multiple Applications  
Disclosed herein are viral vectors suitable for transfection into woody trees for purposes of delivering and expressing beneficial genes. Specifically exemplified herein are vectors for...
US20170297058 METHODS AND STRUCTURES FOR LIGHT REGULATING COATINGS  
The present disclosure describes various embodiments of a structure for a composite light regulating film, methods of using the composite light regulating film, and for methods of making a...
9794711 Capacitive microphone with integrated cavity  
A capacitive microphone and method of fabricating the same are provided. One or more holes can be formed in a first printed circuit board (PCB). A diaphragm can be surface micromachined onto an...
9790326 Method for preparing dioxyheterocycle-based electrochromic polymers  
A method for preparing a conjugated polymer involves a DHAP polymerization of a 3,4-dioxythiophene, 3,4-dioxyfuran, or 3,4-dioxypyrrole and, optionally, at least one second conjugated monomer in...
US20170294528 HIGH ELECTRON MOBILITY TRANSISTORS WITH IMPROVED HEAT DISSIPATION  
III-nitride based high electron mobility transistors (HEMTs), such as AlGaN/GaN HEMTs on Silicon substrates, with improved heat dissipation are described herein. A semiconductor device having...
9783637 Drug delivery using electrochemically-triggered biodegradable electroactive materials  
A biodegradable electroactive material can be doped with a drug and the drug can be delivered to a living subject by stimulating the material with an electrical potential. The material (in this...
9782328 Devices and methods for securing an anti-leak feeding tube for gastric and/or intestinal use  
Medical device designs for enteral nutrition that inhibit the relative motion of one device member to another device member are herein disclosed. The gastric and/or intestinal feeding tube shaft...
US20170284429 ELECTRO-FLUID TRANSDUCERS  
The present disclosure is directed towards electro-fluid transducers that may influence the flow of a fluid in and around a channel. In one such embodiment, a system comprises a first electrode at...
US20170283854 MULTIPLEXED PCR ASSAY FOR HIGH THROUGHPUT GENOTYPING  
The present invention relates to identification and characterization of polymorphisms in a nucleic acid sample. Methods and compositions for the unbiased amplification of multiple target sequences...
9776154 Material comprising two different non-metallic parrticles having different particle sizes for use in solar reactor  
Disclosed herein is a composite particle comprising a first non-metallic particle in which is dispersed a second non-metallic particle, where the first non-metallic particle and the second...
9775918 Capsid-modified rAAV vectors and methods of use  
Disclosed are tyrosine-modified rAAV vectors, as well as infectious virions, compositions, and pharmaceutical formulations that comprise them. Also disclosed are methods of preparing and methods...
9775335 Durable coating-embedded pesticides with peel and stick mosquito treatment of containers  
Water-holding vessels and containers, such as flower pots, water holding dishes used under plant pots, vases, bird baths, and fountains and storm water inlets, can be coated with novel larvicide...
US20170275337 HIGH-TRANSDUCTION-EFFICIENCY RAAV VECTORS, COMPOSITIONS, AND METHODS OF USE  
The present invention provides AAV capsid proteins comprising modification of one or a combination of the surface-exposed lysine, serine, threonine and/or tyrosine residues in the VP3 region. Also...
US20170275178 ROOM TEMPERATURE MULTIFERROIC THIN FILMS  
Various examples are provided for multiferroic thin films. In one example, a multiferroic thin film device includes a thin film of multiferroic material and an electrode disposed on a side of the...
9775241 Nanotube dispersants and dispersant free nanotube films therefrom  
A degradable polymeric nanotube (NT) dispersant comprises a multiplicity of NT associative groups that are connected to a polymer backbone by a linking group where there are cleavable groups...
9774239 Method and apparatus for providing power  
Embodiments of the subject invention are drawn to power supply units and systems for supplying power to loads. Specific embodiments relate to systems incorporating the loads. The power supply...
9772794 Method and apparatus for big data cloud storage resource management  
A system and method for storage resource management using copy-on-write/read snapshots to redirect the I/O requests without moving the virtual disk is disclosed herein. The system includes storage...
9770491 AAV-mediated gene therapy for RPGR X-linked retinal degeneration  
Described herein are methods of preventing, arresting progression of or ameliorating vision loss and other conditions associated with retinitis pigmentosa and x-linked retinitis pigmentosa in a...