Patents and Patent Applications from University of Florida


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10023920 Sensitive and rapid method for Candidatus liberibacter species detection  
DNA amplification methods using novel primers obtained from the novel genes hyvI and hyvII from the Candidatus Liberibacter asiaticus genome are useful for detecting Ca. L. species in plants and...
10022440 Materials and methods for modulating immune responses  
The present invention provides materials and methods for modulating an immune response. In one embodiment, the present invention provides an initial artificial lymph-node homing environment, and a...
US20180197828 VANISHING VIA FOR HARDWARE IP PROTECTION FROM REVERSE ENGINEERING  
A semiconductor device can include a first metal trace, a first via disposed on the first metal trace, a second metal trace disposed on the first via, and an insulator interposed between the first...
US20180196902 SYSTEM AND METHOD FOR AUTOMATED MODEL CALIBRATION, SENSITIVITY ANALYSIS, AND OPTIMIZATION  
A computer-implemented interface apparatus for automated calibration can include an architecture for automatically managing interchangeable input parameters, interchangeable output objective...
US20180194716 THERAPEUTIC COMPOUNDS AND METHODS OF USE  
The invention relates to protein biding interacting/binding compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for...
US20180193489 RECOMBINANT ADENO-ASSOCIATED VIRUS VECTORS TO TARGET MEDULLARY THYROID CARCINOMA  
Provided herein are nucleic acids, recombinant adeno-associated virus (rAAV) particles, and compositions, as well as methods of use thereof for transducing medullary thyroid carcinoma cells and in...
US20180193437 COMPOSITIONS AND METHODS FOR REDUCING ORGAN REJECTION BY REDUCING HEPARAN SULFATE IN DONOR TRANSPLANTS  
Disclosed here are polypeptides, derived from the Myxomavirus-derived secreted glycoprotein, M-T7, comprising point mutations that interfere with chemokine-glycosaminoglycan binding. Compositions...
10017747 Citrus tristeza virus based vectors for foreign gene/s expression  
Disclosed herein are viral vectors based on modifications of the Citrus Tristeza virus useful for transfecting citrus trees for beneficial purposes. Included in the disclosure are viral vectors...
10017458 Therapeutic tetrahydronaphthalene compounds  
The invention relates to protein binding interacting/binding compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for...
10016371 Antigen-specific, tolerance-inducing microparticles and uses thereof  
The present invention provides antigen-specific, tolerance-inducing microparticles for the targeted delivery of therapeutic agents to immune cells. In addition, the present invention allows for...
US20180189899 USING LOADS WITH DISCRETE FINITE STATES OF POWER TO PROVIDE ANCILLARY SERVICES FOR A POWER GRID  
A system, method and apparatus for providing ancillary services to a power grid using a power consumption component at a customer premises. The apparatus may control a load with discrete, finite...
US20180186061 CATHETER FOR ANTIMICROBIAL CONTROL AND METHOD OF MANUFACTURING THEREOF  
Disclosed herein is a method comprising transporting a conduit and a template through a guide tube; the template being disposed on an outer surface of the conduit between the conduit and the guide...
10013569 Privacy-preserving data collection, publication, and analysis  
A data collection procedure is described, which can be performed automatically for each subject of a study as the participant produces the data being collected. In one case, the procedure...
10011640 Capsid-modified rAAV vector compositions and methods therefor  
Disclosed are capsid-modified rAAV expression vectors, as well as infectious virions, compositions, and pharmaceutical formulations containing them. Also provided are methods of preparing and...
10010569 Seaweed extracts, unsaturated fatty acids, and methods of treatment  
The instant invention relates to seaweed extract compositions, processes for isolation, isolated active agents, and methods of treating disease, disorders and conditions in a subject, including,...
10010535 Desferrithiocin analogs and uses thereof  
Iron overload is associated with pathological conditions such as oxidative stress, transfusional iron overload, thalassemia, primary hemochromatosis, secondary hemochromatosis, diabetes, liver...
10010288 Screening for neurological disease using speech articulation characteristics  
Detection of neurological diseases such as Parkinson's disease can be accomplished through analyzing a subject's speech for acoustic measures based on human factor cepstral coefficients (HFCC)....
US20180182501 NUCLEAR REACTOR HAVING EFFICIENT AND HIGHLY STABLE CARBON-BASED THERMAL TRANSFER FLUID  
A pressurized water nuclear reactor (PWNR) includes a core having a containment shield surrounding a reactor vessel having fuel assemblies that contain fuel rods filled with fuel pellets, and...
US20180179620 NICKEL TITANIUM ALLOYS, METHODS OF MANUFACTURE THEREOF AND ARTICLE COMPRISING THE SAME  
Disclosed herein is a shape memory alloy comprising 45 to 50 atomic percent nickel; and 1 to 30 atomic percent of at least one metalloid selected from the group consisting of germanium, antimony,...
US20180177776 COMPOSITIONS FOR THE TREATMENT OF CANCER AND USES THEREOF  
The invention pertains to compositions comprising inhibitors of PI3K, AKT and/or mTOR, one or more 4-quinolinemethanols and a pharmaceutically acceptable excipient. These compositions can contain...
10006049 Hairpin mRNA elements and methods for the regulation of protein translation  
The present invention provides novel mRNA elements capable of forming hairpin, double-stranded RNA structures independent of other non-coding RNAs. These mRNAs are stably expressed, lack...
10005569 Triple flywheel assembly with attitude jitter minimization  
Various embodiments of the present invention include assemblies and methods for minimizing the amplitude of attitude jitter. In one embodiment, a flywheel assembly for reducing the amplitude of...
US20180171157 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL  
An article has a surface topography for resisting bioadhesion of organisms and includes a base article having a surface. A composition of the surface includes a polymer. The surface has a...
US20180171083 FIBER REINFORCED ELASTOMERIC SHEETS WITH TUNABLE STRAIN RELATIONSHIPS  
A soft structure fiber reinforcement technology is provided. In an example embodiment, the fiber reinforced elastomeric sheet comprises a sheet of elastomeric matrix; and a fiber array comprising...
US20180169217 MATERIALS AND METHODS FOR RESPIRATORY DISEASE CONTROL IN CANINES  
The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and...
US20180168139 Furniture Protector Against Bed Bugs and Other Crawling Insects  
Pitfall traps, coasters, devices, apparatus, systems and methods for capturing crawling insects, such as bed bugs, and/or for preventing the insects from climbing up furniture legs to furniture...
9999500 Anti thrombogenic heart valve and medical implements  
Disclosed herein are heart valves made from a polymeric material, such as silicone. Specifically exemplified are heart valve embodiments made from a one or two-pieces of material, or which have...
US20180166399 LAYOUT-DRIVEN METHOD TO ASSESS VULNERABILITY OF ICS TO MICROPROBING ATTACKS  
A method of assessing vulnerability of Integrated Circuit (IC) can include: preparing a list of logic nets of the IC; obtaining rectangular segments from the logic nets; finding a milling...
US20180165526 GATOREYE SYSTEM FOR SMART TRANSPORTATION  
Various examples are provided for smart transportation and sensing systems. In one example, an apparatus for smart transportation sensing includes a reflector integrated in a contoured roadway...
US20180165478 UNIQUIFIED FPGA VIRTUALIZATION APPROACH TO HARDWARE SECURITY  
Novel methods of virtualization with unique virtual architectures on field-programmable gate arrays (FPGAs) are provided. A hardware security method can include providing one or more...
US20180161295 TREATMENT OF CLOSED HEAD INJURY AND HEMORRHAGIC STROKE WITH HBED  
The present invention provides methods for treating closed head injuries or hemorrhagic strokes using a compound of Formula (I), or a pharmaceutically acceptable salt thereof. Compounds of Formula...
9997571 Method and apparatus for providing a charge blocking layer on an infrared up-conversion device  
Embodiments of the invention are directed to an improved device for sensing infrared (IR) radiation with up-conversion to provide an output of electromagnetic radiation having a shorter wavelength...
9995882 Photonic synthesis of large aperture telescopes from multi-telescope arrays  
The present invention provides a telescope array and related components and methods. In various embodiments, the telescope array may include a plurality of telescopes, each telescope associated...
9995757 Point of care sickle cell test  
The disclosure provides methods, kits, and devices for determining an amount of hemoglobin S and/or an amount of total hemoglobin, and optionally, expressing the amount of hemoglobin S as a...
9995643 Detection of static tip resistance of a pile  
Systems and methods are provided for dynamically determining a static tip resistance of a dynamically-loaded component having a tip. One example method comprises receiving gauge data from one or...
9994599 Biaryl ligands  
Embodiments of the present disclosure provide for biaryl ligands (also referred to herein as “biaryl compound”), biaryl complexes, methods of making biaryl compounds, methods of making single...
9994535 Desferrithiocin polyether analogues  
Compounds represented by structural formulas described herein, such as Structural Formula (I): or a pharmaceutically acceptable salt thereof are useful in treating conditions such as metal...
9992989 Dual action lethal containers, systems, methods and compositions for killing adult mosquitos and larvae  
Dual action lethal containers, systems, methods, compositions and formulas used to kill mosquitoes and their larvae. The containers can have separate interior larvicidal and adulticidal coatings...
US20180159368 WIRELESS POWER TRANSFER USING ONE OR MORE ROTATING MAGNETS IN A RECEIVER  
The present disclosure is directed towards wireless power transfer using one or more rotating magnets in a receiver. An exemplary embodiment provides for a system comprising a transmitter that...
US20180154492 HYBRID TOOL WITH BOTH FIXED-ABRASIVE AND LOOSE-ABRASIVE PHASES  
Various examples are provided for hybrid tools including fixed-abrasive and loose- abrasive phases. In one example, a hybrid tool for finishing an internal surface of a workpiece includes a...
US20180153826 MATERIALS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS  
In preferred embodiments, the invention pertains to the treatment of Cystic Fibrosis (CF) using an agonistic of CaSR. In a specific embodiment, the subject invention provides a method of treating...
US20180153528 COAXIAL BIOPSY NEEDLES  
Various examples of methods, devices, apparatus and systems are provided for coaxial biopsy needles. In one example, a coaxial biopsy needle includes an external needle including cutting edges at...
US20180153469 WIRELESS BATTERY-FREE DIAGNOSTIC MOUTH GUARD  
Various examples of methods, systems, and apparatus are provided for monitoring using an improved mouth guard apparatus. In one example, a battery-free diagnostic mouth guard includes a biting...
9987313 Lactobacillus supplement for alleviating type 1 diabetes  
Isolated Lactobacillus strains are useful in preventing or delaying the development of Type 1 Diabetes (T1D). A probiotic composition comprising the Lactobacillus strains and use of the...
9987306 Materials and methods for prevention and treatment of diarrhea and inflammation in the gastrointestinal tract  
The present invention pertains to the use of the calcium-sensing receptor (CaSR)-activating nutrients (designated as “CaSR-based nutrients”) for the prevention and/or treatment of diarrheal...
US20180152824 AD-HOC SOCIAL NETWORK (AHSN) SYSTEM, AHSN-ENABLED DEVICE, AND METHODS OF USE  
Embodiments include a system comprising: a publisher communication device configured to publish a social message for the publisher device for delivery using a short-range wireless communication...
9985153 Air stable infrared photodetectors from solution-processed inorganic semiconductors  
A photodetector has a photoactive layer of semiconducting inorganic nanoparticles positioned between a hole transport electron blocking layer of a first metal oxide and an electron transport hole...
9985101 Encapsulated nanostructures and method for fabricating  
Various nanostructures, including silicon nanowires and encapsulated silicon nanoislands, and methods of making the nanostructures are provided. The methods can include providing a fin structure...
9982330 Nickel titanium alloys, methods of manufacture thereof and article comprising the same  
Disclosed herein is a shape memory alloy comprising 48 to 50 atomic percent nickel, 15 to 30 atomic percent hathium, 1 to 5 atomic percent aluminum; with the remainder being titanium. Disclosed...
9982209 Low-wear fluoropolymer composites  
A low-wear fluoropolymer composite body comprises at least one fluoropolymer and additive particles dispersed therein. Also provided is a process for the fabrication of such a fluoropolymer...