Patents and Patent Applications from University of Connecticut


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9790158 Substituted tropolone derivatives and methods of use  
The compositions and methods described herein relate generally to substituted tropolone derivatives, which, among other features, are useful as histone deacetylase (HDAC) inhibitors.
US20170290864 MESENCHYMAL-LIKE STEM CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS, METHODS AND USES THEREOF  
The disclosure provided herein relates generally to mesenchymal-like stem cells “hES-T-MiSC” or “T-MSC” and the method of producing the stem cells. The method comprises culturing embryonic stem...
9785789 Method and system for verification and authentication using optically encoded QR codes  
An optical security method for object authentication using photon-counting encryption implemented with phase encoded QR codes. By combining the full phase double-random-phase encryption with...
9783616 Regulating transplant rejection of donor and embryonic stem cell-derived tissues and organs  
The invention provides methods and cells for improved transplantation of donor transplants to subjects in need thereof.
9782791 High frequency uniform droplet maker and method  
Systems, methods, and devices are disclosed for producing substantially uniform droplets. The system includes a fluid reservoir vessel defining a fluid reservoir, a separation membrane at one end...
US20170284999 Metal Oxide Based Sensors for Sensing Low Concentration of Specific Gases Prepared by A Flame Based Process  
Improved sensor assemblies are provided. More particularly, the present disclosure provides improved and highly advantageous metal oxide based sensor assemblies configured to sense low...
PP28409 Buddleia plant named ‘UCONNBD599’  
A new and distinct cultivar of Buddleia plant named ‘UCONNBD599’, characterized by its relatively compact, upright and outwardly spreading plant habit; freely branching habit and thick stems with...
PP28408 Buddleia plant named ‘UCONNBD603’  
A new and distinct cultivar of Buddleia plant named ‘UCONNBD603’, characterized by its relatively compact, upright and outwardly spreading plant habit; freely branching habit and thick stems with...
PP28372 Buddleia plant named ‘UCONNBD604’  
A new and distinct cultivar of Buddleia plant named ‘UCONNBD604’, characterized by its relatively compact, upright and outwardly spreading plant habit; freely branching habit and thick stems with...
9755060 Fabrication methodology for optoelectronic integrated circuits  
A method of forming an integrated circuit employs a plurality of layers formed on a substrate including i) bottom n-type ohmic contact layer, ii) p-type modulation doped quantum well structure...
US20170249988 Reconfigurable Phase Change Device  
A reconfigurable phase change device with methods for operating and forming the same are disclosed. An example device can comprise a reconfigurable layer comprising a phase change material, and a...
9745751 Reinforced structural column system  
Improved structural column assemblies and related fabrication methods are provided. More particularly, the present disclosure provides improved systems/methods for the design and fabrication of...
US20170240680 BIO-REDUCIBLE SELF-ASSEMBLED LIQUID CRYSTALLINE BLOCK COPOLYMER FOR DRUG DELIVERY  
The disclosure provides biodegradable amphiphilic liquid crystalline copolymers that can readily self-assemble to nanoparticles in aqueous solutions and also allow for encapsulation of hydrophobic...
US20170239395 Gradient Porous Scaffolds  
The present invention provides gradient porous scaffolds for bone regeneration and osteochondral defect repair, methods for making such gradient porous scaffolds, and methods for using the...
US20170231135 Aronia Plant Named 'UCONNAM165'  
A new and distinct Aronia cultivar named ‘UCONNAM165’ is disclosed, characterized by a compact, dense plants maturing to approximately 2 feet tall and 3 to 4 feet wide. Foliage is uniquely small...
US20170231133 Aronia plant named 'UCONNAM166'  
A new and distinct Aronia cultivar named ‘UCONNAM166’ is disclosed, characterized by a distinctly upright plant form, reaching a mature height between 4 to 5 feet. Vigorous but controlled plant...
US20170225746 ARTICLE WITH CONTROLLABLE WETTABILITY  
An article with controllable wettability includes a substrate and a layer of a composite material supported on the substrate. The layer has an exposed surface and the composite material includes...
US20170224799 IDENTIFICATION OF IMMUNOLOGICALLY PROTECTIVE NEO-EPITOPES FOR THE TREATMENT OF CANCERS  
Described herein are methods of identifying immunologically protective neo-epitopes from the cancer tissue DNA of cancer patients using biophysical principles as well as bioinformatics techniques....
9725698 Trophoblast-derived mesenchymal stem cells (T-MSCs) produced from human embryonic stem cells, methods and uses thereof  
The disclosure provided herein relates generally to mesenchymal-like stem cells “hES-T-MiSC” or “T-MSC” and the method of producing the stem cells. The method comprises culturing embryonic stem...
US20170222400 OPTOELECTRONIC INTEGRATED CIRCUIT  
A semiconductor device includes an n-type ohmic contact layer, cathode and anode electrodes, p-type and n-type modulation doped quantum well (QW) structures, and first and second ion implant...
US20170221995 SPLIT-ELECTRODE VERTICAL CAVITY OPTICAL DEVICE  
A split electrode vertical cavity optical device includes an n-type ohmic contact layer, first through fifth ion implant regions, cathode and anode electrodes, first and second injector terminals,...
US20170209436 ITRACONAZOLE ANALOGUES AND METHODS OF USE THEREOF  
Disclosed herein are analogues of itraconazole that are both angiogenesis and hedgehog signaling pathway inhibitors. The compounds are expected to be useful in the treatment of cancer,...
9707322 Gradient porous scaffolds  
The present invention provides gradient porous scaffolds for bone regeneration and osteochondral defect repair, methods for making such gradient porous scaffolds, and methods for using the...
9701911 Process for converting fats, oils and greases into fuels  
A method for producing a light oil fraction from plant-based and/or animal-based fats, oils or greases is disclosed. The method comprises introducing a feedstock including free fatty acids into a...
9698700 Predictive current control in bidirectional power converter  
A power converter can be controlled to generate a target output power. The control process may include obtaining a target current reference for the power converter, sensing an output current of...
9698457 Optoelectronic integrated circuitry for transmitting and/or receiving wavelength-division multiplexed optical signals  
A WDM transmitter and/or receiver optoelectronic integrated circuit includes a plurality of microresonators and corresponding waveguides and couplers that are integrally formed on a substrate. For...
US20170184788 OPTOELECTRONIC INTEGRATED CIRCUITRY FOR TRANSMITTING AND/OR RECEIVING WAVELENGTH-DIVISION MULTIPLEXED OPTICAL SIGNALS  
A WDM transmitter and/or receiver optoelectronic integrated circuit includes a plurality of microresonators and corresponding waveguides and couplers that are integrally formed on a substrate. For...
US20170179684 DUAL WAVELENGTH HYBRID DEVICE  
A Dual-wavelength hybrid (DWH) device includes an n-type ohmic contact layer, cathode and anode terminal electrodes, first and second injector terminal electrodes, p-type and n-type modulation...
US20170178762 Graphene/Graphite Polymer Composite Foam Derived from Emulsions Stabilized by Graphene Kinetic Trapping  
The present disclosure provides advantageous graphene/graphite stabilized composites (e.g., graphene/graphite stabilized emulsion-templated foam composites), and improved methods for fabricating...
9685261 Formation of a transparent conductive film by interfacial graphene assembly  
Advantageous films and coatings (e.g., transparent conductive films), and improved methods for fabricating such films and/or coatings, are provided. The improved methods for fabricating...
9684193 Optical closed loop microresonator and thyristor memory device  
A semiconductor device that includes an optical resonator spaced from a waveguide structure to provide for evanescent-wave optical coupling therebetween. The optical resonator includes a closed...
9684192 Optical closed loop microresonator and thyristor memory device  
A semiconductor device that includes an optical resonator spaced from a waveguide structure to provide for evanescent-wave optical coupling therebetween. The optical resonator includes a closed...
US20170169733 MODULAR SURGICAL SIMULATION TRAINER AND METHODS OF USE  
The invention is directed to a modular surgical simulation trainer that makes use of anatomic surrogates placed within a housing to simulate a wide variety of various medical conditions including...
9680102 Formation of conjugated polymers for solid-state devices  
Disclosed herein is a facile process for the formation of conjugated polymers inside or outside assembled solid-state devices. One process generally involves applying a voltage to a device...
9679987 Fabrication methodology for optoelectronic integrated circuits  
A method of forming an integrated circuit employs a plurality of layers formed on a substrate including i) n-type modulation doped quantum well structure (MDQWS) structure with n-type charge...
US20170156652 SENSORS FOR ANALYTE DETECTION AND METHODS OF MANUFACTURE THEREOF  
Disclosed herein is a sensor comprising a conduit; the conduit comprising an organic polymer; a working electrode; the working electrode being etched and decorated with a nanostructured material;...
9669076 Albumin-free factor VIII formulations  
A Factor VIII composition formulated without albumin, comprising the following formulation excipients in addition to Factor VIII: 4% to 10% of a bulking agent selected from the group consisting of...
9657145 Metal ester polymer compositions, methods of manufacture, and uses thereof  
Disclosed are transition metal or group II metal ester polymers where the metal is an alkaline earth, transition metal or aluminum; methods of manufacture, and uses thereof. The metal ester...
9650365 Itraconazole analogues and methods of use thereof  
Disclosed herein are analogs of itraconazole that are both angiogenesis and hedgehog signaling pathway inhibitors. The compounds are expected to be useful in the treatment of cancer, particularly...
9646735 Graphene/graphite polymer composite foam derived from emulsions stabilized by graphene/graphite kinetic trapping  
The present disclosure provides advantageous graphene/graphite stabilized composites (e.g., graphene/graphite stabilized emulsion-templated foam composites), and improved methods for fabricating...
9644313 Electrically conductive synthetic fiber and fibrous substrate, method of making, and use thereof  
Electrically conductive synthetic fiber and fibrous substrate (e.g. synthetic leather) are disclosed. The electrically conductive polymeric fiber and polymeric fibrous substrate are made...
9636424 Composition, method, system and kit for optical electrophysiology  
The present invention provides a method of optical electrophysiological probing, including: providing a fluorescing chemical probe; contacting a thick portion of tissue with the fluorescing...
US20170112787 METHODS OF TREATMENT OF INFLAMMATION OF THE GUT  
Described herein are methods of improving immune homeostasis in the gut of a subject suffering from an autoimmune disease characterized by inflammation of the gut by administering, e.g., orally...
9625647 Optoelectronic integrated circuit  
A semiconductor device employs an epitaxial layer arrangement including a first ohmic contact layer and first modulation doped quantum well structure disposed above the first ohmic contact layer....
US20170102545 WEARABLE 3D AUGMENTED REALITY DISPLAY WITH VARIABLE FOCUS AND/OR OBJECT RECOGNITION  
A wearable 3D augmented reality display and method, which may include 3D integral imaging optics.
US20170100455 USING HEAT SHOCK PROTEINS TO IMPROVE THE THERAPEUTIC BENEFIT OF A NON-VACCINE TREATMENT MODALITY  
The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or an α-2-macroglobulin (α2M) preparation with a...
9621063 Reference current generation in bidirectional power converter  
A power converter can be controlled to generate a target output power based on a reactive power reference and an active power reference. The control process may include monitoring a time-varying...
9614112 Imaging cell array integrated circuit  
A semiconductor device is provided that includes an array of imaging cells realized from a plurality of layers formed on a substrate, wherein the plurality of layers includes at least one...
US20170087218 FACTOR VIII FORMULATIONS  
A Factor VIII (FVIII) composition formulated such that NaCl is not present in the final formulation or is present in trace amounts, which allows for a concomitant reduction in the lyophilization...
9603368 Microbial carriers for targeted delivery of agricultural payloads  
The present invention provides compositions that include an agriculturally suitable carrier and encysted or sporulated protozoa present on or in the agriculturally suitable carrier, for use in...