Patents and Patent Applications from University of Cincinnati


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US20170308672 METHODS FOR DETERMINING RISK AND TREATING DISEASES AND CONDITIONS THAT CORRELATE TO WEATHER DATA  
Methods and model equations are provided for predicting a risk of a subject who experiences adverse medical events associated with the weather, of experiencing a new-onset event. Methods include...
9796121 Methods of growing carbon nanotubes and forming a carbon nanotube thread  
A method of forming an array of aligned, uniform-length carbon nanotubes on a planar surface of a substrate employing a composite catalyst layer of iron and cobalt. The carbon nanotubes have...
9795618 Methods and compositions for suppressing IgE-mediated anaphylaxis  
Methods for suppressing IgE-mediated anaphylaxis are provided herein, which include administering to a person in need thereof a combination of at least two therapeutic agents selected from the...
US20170295776 RED BLOOD CELL STORAGE SOLUTIONS, SOLUTION ADDITIVES, AND METHODS FOR IMPROVING THE STORAGE OF RED BLOOD CELLS  
Methods, additive kits and storage compositions for decreasing the deleterious effects of storage on pRBCs, for improving the aging process of stored pRBCs, and for preventing or ameliorating...
US20170292835 MEASURING WALL THICKNESS LOSS FOR A STRUCTURE  
Systems, methods and computer storage mediums accurately measure wall thickness in a region of interest included in complex curved structures. Embodiments of the present disclosure relate to...
US20170281377 METHODS FOR MAKING MAGNESIUM BIODEGRADABLE STENTS FOR MEDICAL IMPLANT APPLICATIONS  
Methods for making a magnesium biodegradable stent for medical implant applications, using magnesium foil or pure magnesium or magnesium alloys that are biodegradable and performing a lithographic...
9777279 Methods and compositions for treating autoimmune disorders by targeting Kv1.3 ion channels with functionalized lipid-derived nanovesicles  
Synthesis and pharmaceutical compositions of antibody-functionalized nanovesicles encapsulating ion channel knockout siRNA, and methods of treating autoimmune diseases associated with increased...
US20170274043 Therapeutic Uses of CD137pos Regulatory T Cells in Treating Autoimmune Diseases  
A method for treating or preventing a T-cell-mediated autoimmune disease is provided herein, the method including administering to a mammal in need thereof a therapeutically effective amount of...
US20170274042 Pharmaceutical Compositions Comprising Soluble CD137  
A method for treating or preventing a T-cell-mediated autoimmune disease is provided herein, the method including administering to a mammal in need thereof a therapeutically effective amount of...
9758593 Compositions and methods for treating cocaine-related disorders  
Methods for treating a cocaine-related disorder in an individual include administering to the individual a therapeutic amount of an antibody comprising a human immunoglobulin gamma heavy chain and...
9757432 Materials and methods useful for treating glioblastorna  
The present invention provides compositions and methods useful for treating cancers such as glioblastoma. SapC-DOPS was found to be synergistically effective at inducing cell death when...
9753273 Electrofluidic display and methods for making  
A method for manufacturing a freestanding film having at least one population of through holes cumulatively totaling at least 1% of the film area, wherein the standard deviation of hole diameters...
9751765 Methods to superheat carbon nanotubes  
A method for annealing multi-walled carbon nanotubes includes applying a high-frequency electromagnetic field to the carbon nanotubes and causing the carbon nanotubes to self-heat to a temperature...
US20170248035 ENHANCED DRY-COOLING SYSTEM AND METHOD FOR INCREASING POWER PLANT EFFICIENCY AND OUTPUT  
The presently disclosed subject matter relates to enhanced dry-cooling systems and methods. More specifically, the presently disclosed subject matter relates to enhanced dry-cooling systems for...
US20170245788 SWEAT SENSING WITH ANALYTICAL ASSURANCE  
A sweat sensor device (200) with analytical assurance includes at least one sensor (220) for detecting a first analyte, and at least one calibration medium (270) containing at least the first...
US20170239386 MAGNESIUM SINGLE CRYSTAL FOR BIOMEDICAL APPLICATIONS AND METHODS OF MAKING SAME  
A biomedical implant (16, 18) is formed from magnesium (Mg) single crystal (10). The biomedical implant (16, 18) may be biodegradable. The biomedical implant (16, 18) may be post treated to...
9732235 Corrosion resistant hybrid silanized epoxy ester resins, coatings and surface pre-treatment formulations  
A self-healing coating composition for use on metals includes a polyurea, an epoxy ester unsaturated resin, a combination of amine terminated siloxane and epoxy terminated siloxane and an...
9730980 Method of treating type I diabetes using apolipoprotein A-IV  
Methods for treating type one diabetes mellitus in a subject in need thereof and pharmaceutical compositions for the treatment of type one diabetes mellitus are disclosed, including combination...
US20170199373 DOSING AND SEALING OF FLUID-BASED ELECTRO-OPTICAL DEVICES AND DISPLAYS  
A method for manufacturing an electrofluidic device comprising the steps of providing a first plate with features for holding a first fluid, filling a first fluid into features on a first plate;...
9689671 Measuring wall thickness loss for a structure  
Systems, methods and computer storage mediums accurately measure wall thickness in a region of interest included in complex curved structures. Embodiments of the present disclosure relate to...
US20170172484 COMBINATORIAL SENSING OF SWEAT BIOMARKERS USING POTENTIOMETRIC AND IMPEDANCE MEASUREMENTS  
A wearable sweat sensor device (1) may include a plurality of sensors (150, 160, 170, 180) capable of measuring a plurality of ion-selective biomarker potentials and a mechanism that analyzes a...
9682066 Methods of treating primary brain tumors by administering letrozole  
The present disclosure relates to the field of cancer treatment, and more specifically to the field of treatment of primary malignant brain tumors. Provided herein are methods of treating primary...
9678072 Synthetic ligands for the differentiation of closely related toxins and pathogens  
Synthetic ligand compounds and methods of differentiating between Shiga toxin 1 and Shiga toxin 2 are disclosed herein. Another embodiment includes a kit for differentiating between Shiga toxin 1...
9675820 Ultrasound-mediated inducement, detection, and enhancement of stable cavitation  
Methods and systems for passively detecting stable cavitation and enhancing stable cavitation during sonothrombolysis are provided. The method of passively detecting stable cavitation includes...
US20170162881 MULTI-FUNCTIONAL POROUS CARBON-SUPPORTED MICROPOROUS INORGANIC MEMBRANES FOR REDOX FLOW BATTERIES  
A separator for a redox flow battery includes a support layer having a first side, and a zeolite layer formed on the first side of the support layer. The support layer includes a porous substrate...
9669203 Methods of enhancing delivery of drugs using ultrasonic waves and systems for performing the same  
Methods and systems for inducing and passively detecting stable cavitation and/or inertial cavitation for targeted drug delivery across a biological membrane are disclosed. Such methods include...
9655752 Methods for making magnesium biodegradable stents for medical implant applications  
Methods for making a magnesium biodegradable stent for medical implant applications, using magnesium foil or pure magnesium or magnesium alloys that are biodegradable and performing a lithographic...
US20170135594 Non-Invasive Detection of Spreading Depolarization Using Scalp Electroencephalography  
Non-invasive electroencephalogram (EEG)-based methods for detecting a spreading depolarization secondary to a brain injury in a patient who exhibits high-amplitude delta activity in at least one...
US20170128418 COMPOSITIONS AND METHODS FOR IMPROVING LACTATION  
The present disclosure relates to the use of pharmaceutical agents to manipulate serotonin in animal mammary glands. Use of the serotonin agents results in increased PTHrP levels, resulting in the...
9625705 Dosing and sealing of fluid-based elctro-optical devices and displays  
A method for manufacturing an electrofluidic device comprising the steps of providing a first plate with features for holding a first fluid, filling a first fluid into features on a first plate;...
US20170100102 ADVANCED SWEAT SENSOR ADHESION, SEALING, AND FLUIDIC STRATEGIES  
A sweat sensor device (200) includes one or more sweat sensors (220) and a seal (280) covering the one or more sweat sensors (220). The seal (280) is adapted to protect the sweat sensors (220)...
US20170095233 DEVICES WITH REDUCED SWEAT VOLUMES BETWEEN SENSORS AND SWEAT GLANDS  
A sweat sensor device (400c) for sensing sweat on the skin (12) includes one or more sweat sensors (420) and a volume-reducing component that provides a volume-reduced pathway (480) for sweat...
US20170095184 SWEAT MONITORING AND CONTROL OF DRUG DELIVERY  
The concentration of an administered compound, such as a drug (D), in an organ or a bodily fluid, such as blood, is determined directly through detecting the drug (D) or its metabolites (DM) in...
US20170095183 VERTICAL-FLOW ELECTRONIC BIO-CHEMICAL SENSING DEVICES  
An electronic sweat sensor (300) includes a plurality of porous substrates (310, 312), each porous substrate (310, 312) having an electrically conductive surface (320, 322). The porous substrates...
US20170074893 DEVICES AND METHODS FOR ANALYZING A BLOOD COAGULATION PROPERTY  
A device (10) and method for analyzing blood coagulation in a blood sample. The device (10) includes a housing (12) having an analytical membrane (14) partially enclosed in a housing. The...
US20170071210 SILVER NANOPARTICLE-ENHANCED PHOTOSENSITIZERS  
The present invention relates generally to compositions and methods of killing bacteria using a surface plasmon coupled to a photosensitizer. A nanostructure (10) may include a silver nanoparticle...
9585870 Compositions and methods for improving lactation  
The present disclosure relates to the use of pharmaceutical agents to manipulate serotonin in animal mammary glands. Use of the serotonin agents results in increased PTHrP levels, resulting in the...
9581629 Sensor sleeve for health monitoring of an article  
A sensor sleeve for use in detecting a failure in an article (e.g., a hydraulic hose), the sensor sleeve includes an insulator layer that separates two electrode layers. As such, the electrode...
US20170044680 ADDITIVE MANUFACTURING BY LOCALIZED ELECTROCHEMICAL DEPOSITION  
A method of electrolytic additive manufacturing provides 3-D parts. The method can be used to form parts from particulate material in an electrolytic bath. Metal is electrolytically deposited,...
US20170035425 METHODS FOR PARTIAL DIVERSION OF THE INTESTINAL TRACT  
Devices and methods are used to modify a metabolic pathway of a digestive system by creating a pathway within the intestinal tract through an anastomosis between a proximal location within the...
US20170029523 STIMULATION VIA TLR4/MD-2 TO REVERSE TYPE 1 DIABETES  
Disclosed are methods and compositions for treating Type I diabetes in a subject. Agents selected from a TLR4 agonist, a TLR4/MD-2 agonist, or a combination thereof may be used in the disclosed...
9555109 Method of inhibiting cell proliferation induced by alternatively spliced tissue factor by administering a monoclonal antibody  
Embodiments of the invention are directed to a method of inhibiting proliferation of a cell induced by asTF that includes exposing the proliferating cell to an inhibitor of asTF at a concentration...
US20170016899 Methods of Detecting Influenza Virus  
Provided herein is a method of detecting the presence of influenza virus in a sample while minimizing false positives due to presence of one or more other pathogens in the sample, the method...
US20160376654 Temporal Pediatric Sepsis Biomarker Risk Model  
Methods and compositions disclosed herein generally relate to methods of identifying, validating, and measuring clinically relevant, quantifiable biomarkers of diagnostic and therapeutic responses...
US20160376447 CORROSION RESISTANT HYBRID SILANIZED EPOXY ESTER RESINS, COATINGS AND SURFACE PRE-TREATMENT FORMULATIONS  
A self-healing coating composition for use on metals includes a polyurea, an epoxy ester unsaturated resin, a combination of amine terminated siloxane and epoxy terminated siloxane and an...
9526514 Patient-specific assemblies, jigs, and methods for a personalized total hip arthroplasty system  
A patient-specific total hip arthroplasty system including surgical guide and jig instrumentation modeled by computer aided design using image data derived from a specific patient's relevant...
9506855 Method and system for analyzing a colorimetric assay  
Described herein is a method, system and computer program for analyzing a colorimetric assay that includes obtaining an image of the assay, optionally correcting for ambient lighting conditions in...
9487816 Methods of detecting influenza virus  
Provided herein is a method of detecting the presence of influenza virus in a sample while minimizing false positives due to presence of one or more other pathogens in the sample, the method...
US20160318849 Hydrogen Peroxide-Activated Compounds as Selective Anti-Cancer Therapeutics  
Provided are compounds according to the following Formula I: The Formula I compounds are activated in the presence of hydrogen peroxide and are therefore selective anti-cancer therapeutics for...
9476149 Methods for electrospinning hydrophobic coaxial fibers into superhydrophobic and oleophobic coaxial fiber mats  
Methods for electrospinning a hydrophobic coaxial fiber into a superhydrophobic coaxial fiber mat can include providing an electrospinning coaxial nozzle comprising a core outlet coaxial with a...