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Patents and Patent Applications from University of Cincinnati


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US20150126433 GROWTH FACTORS FOR THE TREATMENT OF MYCOBACTERIAL INFECTION  
Described herein are novel methods and kits for treating mycobacterium infections with KGF. The methods include administering an amount of KGF effective to treat the mycobacterium infection. The...
US20150119437 Methods of Treating Cognitive Dysfunction by Modulating Brain Energy Metabolism  
Methods for treating cognitive dysfunction by modulating brain energy metabolism using cyclocreatine or a pharmaceutically acceptable salt thereof are discussed.
US20150112165 SWEAT SENSING WITH CHRONOLOGICAL ASSURANCE  
Devices that sense sweat and are capable of providing chronological assurance are described. The device uses at least one sensor to measure sweat or its components and to determine a sweat sampling...
US20150112164 DEVICES FOR INTEGRATED, REPEATED, PROLONGED, AND/OR RELIABLE SWEAT STIMULATION AND BIOSENSING  
A sweat sensing device includes a plurality of sweat collection pads communicating with a sensor. Each of the pads is activated by a timing circuit which allows one or more of the pads to be...
US20150105854 Methods for Making Magnesium Biodegradable Stents for Medical Implant Applications  
Methods for making a magnesium biodegradable stent for medical implant applications, using magnesium foil or pure magnesium or magnesium alloys that are biodegradable and performing a lithographic...
US20150080784 METHOD AND DEVICE FOR TREATING A TISSUE WITH A HIGH FREQUENCY ELECTROMAGNETIC FIELD  
Methods and systems for treating a tissue with a high frequency electric field to activate MAPK/ERK pathways, induce angiogenesis, induce angionenic factos such as NO and VEGF, or promote wound...
8980223 Methods of preventing ischemic injury using peripheral nociceptive stimulation  
Methods of inhibiting ischemia-related and ischemia-reperfusion-related injury are provided. Remote administration of a C-fiber activator or TRPV1 agonist or remote electrical stimulation and...
US20150059625 LOW EMISSION FUEL PELLET  
Low emission fuel pellets are formed from fuel sources such as non-recyclable paper and plastic materials by combining sorbent(s) to the interior of the pellet as it is being formed or coating the...
8967143 Acoustic pressure inducers and methods for treatment of obstructive sleep apnea  
Acoustic pressure inducers and methods for treating obstructive sleep apnea are disclosed. In one embodiment, an acoustic pressure inducer includes an actuator housing having an orifice, a tube...
US20150057515 SWEAT SIMULATION, COLLECTING AND SENSING SYSTEMS  
Biological chemicals, potentially found in blood are measured by collecting sweat and determining the concentration or meaning of the selected chemical in sweat. The sweat can be collected using a...
US20150055134 METHOD AND SYSTEM FOR ANALYZING A COLORIMETRIC ASSAY  
Described herein is a method, system and computer program for analyzing a colorimetric assay that includes obtaining an image of the assay, optionally correcting for ambient lighting conditions in...
US20150031741 COMPOSITIONS AND METHODS FOR IMPROVING LACTATION  
The present disclosure relates to the use of pharmaceutical agents to manipulate serotonin in animal mammary glands. Use of the serotonin agents results in increased PTHrP levels, resulting in the...
US20150011469 METHOD OF TREATING DIABETES USING NON-GLYCOSYLATED APOLIPOPROTEIN A-IV  
Methods for treating type two diabetes mellitus in a subject in need thereof and pharmaceutical compositions for the treatment of type two diabetes mellitus are disclosed, wherein the methods and...
8924162 Turbine-to-turbine prognostics technique for wind farms  
Methods and systems for predicting an end of life of a wind turbine component including receiving environmental conditions indicative of natural surroundings of wind turbines within a wind turbine...
US20140378788 COMPUTER SYSTEM AND METHOD FOR ASSESSING DYNAMIC BONE QUALITY  
A computer system for assessing dynamic bone quality is provided, including a memory that stores executable instructions, a central processing unit (CPU) capable of accessing the memory and...
US20140377757 COMPOSITIONS AND METHODS FOR SCREENING FOR CREATINE TRANSPORTER DEFICIENCY  
Amplification primers, sequencing primers, kits for screening, and screening methods for identifying a SLC6A8 creatine transporter gene mutation are disclosed. The screening method includes...
US20140374324 MICROFLUIDIC METHODS FOR PASSIVE SEPARATION OF CELLS AND PARTICLES  
A method of separating a plurality of particles (14) from a portion of fluid, comprising directing the plurality of particles (14) into a microchannel (12). A first portion (16) of particles (14)...
US20140371041 TOTAL BRAIN BALANCE TRAINING EQUIPMENT  
Vestibular-proprioceptive system training devices and methods of using the same. The vestibular-proprioceptive training device comprises a balance board having an upper surface and an under...
US20140370027 INHIBITION OF MACROPHAGE-SYNTHESIZED WNT7B TO INHIBIT TUMOR ANGIOGENESIS AND METASTASIS  
The present invention provides methods of inhibiting angiogenesis in a malignant tumor, inhibiting metastasis of a malignant tumor and of inhibiting transformation of a benign tumor to a malignant...
8912359 Bisbenzamidines for the treatment of pneumonia  
A method of combating infectious agents, such as Pneumocystis pneumonia, and a method of treating a subject in need of such treatment is disclosed. The method comprises administering to the subject...
US20140350676 ELEMENTS FOR VERSATILITY OF A PROSTHETIC ANCHOR  
A prosthetic anchor to be attached to a natural or prosthetic structure of a human or animal. The anchor includes a central layer with first and second surface. A plurality of fiber bundles, each...
US20140342347 Compositions and Methods for the Storage of Red Blood Cells  
The present invention provides an aqueous composition for storage of red blood cells consisting essentially of: adenine; dextrose; at least one nonmetabolizable membrane-protectant sugar; and a...
US20140315012 NANO-GRAPHENE SHEET-FILLED POLYIMIDE COMPOSITES AND METHODS OF MAKING SAME  
A composite material including a dispersion of nano-graphene sheet particles in a polyimide matrix and a method making films of the composite material are provided. The method includes forming a...
US20140308326 ANTIMICROBIAL COMPOSITIONS OF AMINOGLYCOSIDIC ANTIBIOTICS AND ZINC ION CHELATORS SPECIFICALLY FORMULATED FOR ENHANCED INHIBITION OF BACTERIAL COLONIZATION AND ANTIBACTERIAL EFFICACY  
Pharmaceutical compositions comprising an aminoglycosidic antibiotic and at least one zinc-chelating agent in a specified concentration, and methods of inhibiting bacterial colonization, biofilm...
8852128 Computer system and method for assessing dynamic bone quality  
A computer system for assessing dynamic bone quality is provided, including a memory that stores executable instructions, a central processing unit (CPU) capable of accessing the memory and...
US20140287020 SURGICAL DEVICE FOR SKIN THERAPY OR TESTING  
A device, and method of making the device, capable of therapeutic treatment and/or for in vitro testing of human skin. The device may be used on skin wounds for burned, injured, or diseased skin,...
US20140276867 PATIENT-SPECIFIC ASSEMBLIES, JIGS, AND METHODS FOR A PERSONALIZED TOTAL HIP ARTHROPLASTY SYSTEM  
A patient-specific total hip arthroplasty system including surgical guide and jig instrumentation modeled by computer aided design using image data derived from a specific patient's relevant...
US20140274887 Compounds for Control of Appetite  
This invention relates generally to neuropeptide Y (“NPY”) Y4 receptor agonists including pancreatic polypeptide (PP), analogs thereof, and peptide fragments of PP, e.g. PP(32-36), and analogs the...
US20140272942 Methods of Detecting Influenza Virus  
Provided herein is a method of detecting the presence of influenza virus in a sample while minimizing false positives due to presence of one or more other pathogens in the sample, the method...
US20140248289 Methods and Compositions for the Treatment of Respiratory Conditions Via NKG2D Inhibition  
Methods and compositions for the treatment of respiratory conditions are provided. Aspects of the subject methods include administering to the subject a composition comprising an inhibitor of...
US20140243647 APPARATUSES AND METHODS FOR NEUROLOGICAL STATUS EVALUATION USING ELECTROMAGNETIC SIGNALS  
In one embodiment, a neurological status evaluation apparatus includes a signal generator configured to generate an electromagnetic signal at one or more frequencies, a transmitting antenna coupled...
US20140235687 METHODS OF TREATING COGNITIVE DYSFUNCTION BY MODULATING BRAIN ENERGY METABOLISM  
Methods for treating cognitive dysfunction by modulating brain energy metabolism using cyclocreatine or a pharmaceutically acceptable salt thereof are discussed.
8810882 Display pixels, displays, and methods of operating display pixels  
Electrofluidic and electrowetting display pixels, electrofluidic and electrowetting displays, and methods of operating electrofluidic and electrowetting display pixels. The pixel includes a...
US20140220009 Compositions and Methods for Treating Cocaine-Related Disorders  
A method of treating a cocaine-related disorder in an individual is provided, the method including administering to the individual a therapeutic amount of an antibody comprising a human...
US20140208852 MEASURING WALL THICKNESS LOSS FOR A STRUCTURE  
Systems, methods and computer storage mediums accurately measure wall thickness in a region of interest included in complex curved structures. Embodiments of the present disclosure relate to...
8771243 Wound treatment system  
A wound treatment system includes a sponge including a first surface adapted to confront a wound bed of a patient, a drape in contact with a second surface of the sponge, and a vacuum source for...
8765468 Surgical device for skin therapy or testing  
A device, and method of making the device, capable of therapeutic treatment and/or for in vitro testing of human skin. The device may be used on skin wounds for burned, injured, or diseased skin,...
US20140179758 PRNA MUTLIVALENT JUNCTION DOMAIN FOR USE IN STABLE MULTIVALENT RNA NANOPARTICLES  
Trifurcate RNA junction domains derived from phi29 pRNA are described that assemble with high affinity and that are stable in vitro and in vivo. Further expansion of trifurcated RNA domains to...
8753602 Composite catalyst and method for manufacturing carbon nanostructured materials  
A method of forming a carbon nanotube array on a substrate is disclosed. One embodiment of the method comprises depositing a composite catalyst layer on the substrate, oxidizing the composite...
8753392 Elements for versatility of a prosthetic anchor  
A prosthetic anchor to be attached to a natural or prosthetic structure of a human or animal. The anchor includes a central layer with first and second surface. A plurality of fiber bundles, each...
US20140154277 Pharmaceutical Compositions Comprising Soluble CD137  
A method for treating or preventing a T-cell-mediated autoimmune disease is provided herein, the method including administering to a mammal in need thereof a therapeutically effective amount of...
US20140154244 Methods of Treating Primary Brain Tumors by Administering Letrozole  
The present disclosure relates to the field of cancer treatment, and more specifically to the field of treatment of primary malignant brain tumors. Provided herein are methods of treating primary...
US20140148402 Diagnostic Assays and Methods of Treating Pneumonia, Sepsis and Systemic Inflammatory Response Syndrome  
Methods for assessing pneumonia in a patient, methods for managing treatment of a patient suspected of having pneumonia, and methods of managing treatment in a patient suffering from pneumonia. The...
8729227 Compounds for control of appetite  
This invention relates generally to neuropeptide Y (“NPY”) Y4 receptor agonists including pancreatic polypeptide (PP), analogs thereof, and peptide fragments of PP, e.g. PP(32-36), and analogs the...
8709707 Compositions substantially free of sodium chloride and methods for the storage of red blood cells  
The present invention provides an aqueous composition for storage of red blood cells consisting essentially of: adenine; dextrose; at least one nonmetabolizable membrane-protectant sugar; and a...
US20140105956 BIODEGRADABLE POLYMER BASED MICROIMPLANT FOR OCULAR DRUG DELIVERY  
Novel sustained release biodegradable implants and methods of making and of using the same to treat ocular diseases are provided.
8693081 Electrofluidic imaging film, devices, and displays, and methods of making and using the same  
A device and method of making and using the same. The device includes first and second substrates that are spaced to define a fluid space. Polar and non-polar fluids occupy the fluid space. A first...
8685368 Polyamides for nucleic acid delivery  
A new class of non-viral transduction vectors that can be used for both in vivo and in vitro applications, including, a gene transfer vector that has comparable efficiency to a viral vector without...
8673844 Method of inhibiting progression of type 1 diabetes by administering soluble CD137  
A method for treating or preventing a T-cell-mediated autoimmune disease is provided herein, the method including administering to a mammal in need thereof a therapeutically effective amount of...
US20140054067 PRESSURE RECONFIGURED ELECTROMAGNETIC DEVICES  
A reconfigurable electromagnetic device includes a first and second planar layer having facing surfaces. One of the surfaces includes one or more micro-trenches. The area between the two surfaces...