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Patents and Patent Applications from University of California System


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US20140220641 TRANSCRIPTION FACTORS FOR CELLULOSIC ENZYME PRODUCTION  
Provided herein are methods and compositions for increasing the production of one or more cellulases from a fungal host cell. The disclosure is based, on the surprising discovery that...
US20140220587 METHODS FOR GENOME ASSEMBLY AND HAPLOTYPE PHASING  
The disclosure provides methods to assemble genomes of eukaryotic or prokaryotic organisms. The disclosure further provides methods for haplotype phasing and meta-genomics assemblies.
US20140220362 ELECTROCHROMIC NANOCOMPOSITE FILMS  
The present invention provides an electrochromic nanocomposite film. In an exemplary embodiment, the electrochromic nanocomposite film, includes (1) a solid matrix of oxide based material and (2)...
US20140220173 UNIVERSAL HARDWARE PLATFORM AND TOOLSET FOR OPERATING AND FABRICATING MICROFLUIDIC DEVICES  
A microfluidic device platform may include a valve manifold adapted to deliver a programmable pressure to a plurality of ports, a cell chamber having programmable environmental control, and a...
US20140220106 LYMPHATIC ZIP CODES IN TUMORS AND PRE-MALIGNANT LESIONS  
Disclosed herein are compositions and methods for and involving selectively targeting tumor lymphatics.
US20140220005 N-Cadherin: Target for Cancer Diagnosis and Therapy  
The present invention provides methods of diagnosis, providing a prognosis and a therapeutic target for the treatment of cancers that express N-cadherin, including prostrate and bladder cancers.
US20140219971 ALGAL PRODUCED MALARIAL TRANSMISSION BLOCKING VACCINES  
The present invention relates to the production of malaria transmission blocking vaccines in single-celled green algae, particularly algae of the genus Chlamydomonas, e.g., Chlamydomonas...
US20140217785 HEATED AND COOLED CHAIR APPARATUS  
Articles of furniture with a system of heating and cooling that can be integrated into a building environmental control network are provided. The heating/cooling system of the article has surfaces...
8798374 Automated facial action coding system  
An automatic facial action coding system and method can include processing an image to identify a face in the image, to detect and align one or more facial features shown in the image, and to...
8797644 Capillary-based cell and tissue acquisition system (CTAS)  
The present invention relates to a capillary-based cell and tissue acquisition system that integrates the capillary approach with a microscope manipulator to collect and sort cells of interest....
8797233 Systems, methods, and devices for dynamic management of data streams updating displays  
Presented herein are methods, systems, devices, and computer-readable media for systems for dynamic management of data streams updating displays. Some of the embodiments herein generally relate to...
8796912 Interdigitated multiple pixel arrays of light-emitting devices  
The present invention discloses a plurality of interdigitated pixels arranged in an array, having a very low series-resistances with improved current spreading and improved heat-sinking. Each pixel...
8796494 Process for direct conversion of biomass to liquid fuels and chemicals  
A method of catalytically preparing a fluid product from solid carbonaceous material is described. In the method, at least one of the following equilibria is established by one or more catalysts:...
8796233 Methods and systems for modulating hormones and related methods, agents and compositions  
Provided herein are bitter taste receptor ligands, related agents, combinations, compositions, methods and systems for modulating release of a metabolic hormone in vitro or in vivo from cells of...
8796230 Ivermectin antagonizes ethanol inhibition in P2X4 receptors  
A method for reducing alcohol consumption in a subject includes a step of identifying a subject exhibiting at least one symptom of alcoholism and then administering a therapeutically effective...
8796209 Compositions and methods related to anti-FGF agents  
The invention relates to an isolated amino acid that can act as an antagonist to FGF signaling, comprising at least a portion of the FGF protein amino acid sequence, and including a mutation in...
8795781 Methods and devices utilizing soluble conjugated polymers  
Methods, compositions and articles of manufacture involving soluble conjugated polymers are provided. The conjugated polymers have a sufficient density of polar substituents to render them soluble...
8795672 Compositions and methods for cancer immunotherapy  
Provided is a cancer therapeutic agent comprising a cancer targeting molecule linked to a liver-expressed chemokine (LEC). In one embodiment, the cancer targeting molecule is an antibody that...
8795650 Derivation of unlimited quantities of neutrophils or monocyte/dendritic cells  
A method to generate unlimited numbers of macrophage/dendritic cells or neutrophils from mice, using conditional Hox oncoproteins is disclosed. The invention further includes the establishment of a...
8795504 Electrodeposition of platinum/iridium (Pt/Ir) on Pt microelectrodes with improved charge injection properties  
Aspects of the present disclosure are directed to electrochemical approaches for synthesis of platinum-iridium alloys with selected platinum-iridium ratio content and subsequently predetermined...
8795440 Growth of non-polar M-plane III-nitride film using metalorganic chemical vapor deposition (MOCVD)  
A method of growing non-polar m-plane III-nitride film, such as GaN, AlN, AlGaN or InGaN, wherein the non-polar m-plane III-nitride film is grown on a suitable substrate, such as an m-SiC, m-GaN,...
8795430 Method of improving surface morphology of (Ga,Al,In,B)N thin films and devices grown on nonpolar or semipolar (Ga,Al,In,B)N substrates  
A method for improving the growth morphology of (Ga,Al,In,B)N thin films on nonpolar or semipolar (Ga,Al,In,B)N substrates, wherein a (Ga,Al,In,B)N thin film is grown directly on a nonpolar or...
8795193 Devices and methods for suppression of tinnitus  
Methods and devices for treating tinnitus in human or animal subjects wherein the subject is caused to perceive a tinnitus suppressing sound which fully or partially suppresses the subject's...
US20140213922 SYSTEM AND METHOD FOR RECONSTRUCTING CARDIAC SIGNALS ASSOCIATED WITH A COMPLEX RHYTHM DISORDER  
System, assembly and method are provided to facilitate reconstruction of cardiac information representing a complex rhythm disorder associated with a patient's heart to indicate a source of the...
US20140213910 METHOD AND APPARATUS FOR PERFORMING QUALITATIVE AND QUANTITATIVE ANALYSIS OF BURN EXTENT AND SEVERITY USING SPATIALLY STRUCTURED ILLUMINATION  
Frequent monitoring of early-stage burns is necessary for deciding optimal treatment and management. Superficial-partial thickness and deep-partial thickness burns, while visually similar, differ...
US20140213563 METHODS OF DIAGNOSING AND TREATING NEONATAL REVERSION TO FETAL CONSCIOUSNESS  
This invention provides methods of diagnosing and treating syndromes of reversion to fetal consciousness in a neonate.
US20140213527 SMALL HUMANIN-LIKE PEPTIDES  
Novel peptides referred to as small humanin-like peptides (SHLPs) are provided herein along with nucleic acids encoding SHLPs and probes that selectively bind SHLPs. SHLPs have wide-ranging...
US20140212968 SYNTHETIC MATRICES FOR LONG TERM EXPANSION OF PLURIPOTENT HUMAN EMBRYONIC STEM CELLS  
Provided herein is a synthetic polymer-based hydrogel for the self-renewal and expansion of human stem cells such as embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). Also...
US20140212766 BLOCK COPOLYMER BATTERY SEPARATOR  
The invention herein described is the use of a block copolymer/homopolymer blend for creating nanoporous materials for transport applications. Specifically, this is demonstrated by using the block...
US20140211820 TECHNIQUE FOR THE GROWTH AND FABRICATION OF SEMIPOLAR (Ga,Al,In,B)N THIN FILMS, HETEROSTRUCTURES, AND DEVICES  
A method for growth and fabrication of semipolar (Ga,Al,In,B)N thin films, heterostructures, and devices, comprising identifying desired material properties for a particular device application,...
US20140211779 SCALABLE SYNCHRONIZATION FOR DISTRIBUTED MULTIUSER MIMO  
Each wireless access point in a network may transmit pilot bursts; receive pilot bursts; determine the timing, carrier frequency, and/or sampling frequency of each received pilot burst; determine...
US20140210474 LINEAR TRANSFORM FOR DIFFUSION MRI  
Samples of a Fourier transform of a signal may be received that are distributed in a generally spherically-shaped pattern on a surface of at least one sphere. The samples may be assembled to form a...
US20140210469 NONRIGID MOTION CORRECTION IN 3D USING AUTOFOCUSING WITH LOCALIZED LINEAR TRANSLATIONS  
A method for providing an magnetic resonance imaging (MRI) with nonrigid motion correction of an object is provided. An MRI excitation is applied to the object. A magnetic field read out from the...
US20140209683 IDENTIFICATION OF OBJECTS USING PLASMA RESONANT PARTICLES  
A method and apparatus for identifying an object having a pattern of plasmon resonant particles (PREs) distributed in or on the object are disclosed. In the method, a field containing the pattern...
US20140208823 Multi-Axis Chip-Scale MEMS Inertial Measurement Unit (IMU) Based on Frequency Modulation  
A multi-axis microelectromechanical-systems (MEMS) inertial measurement unit (IMU) is fabricated in a vacuum sealed single packaged device. An FM vibratory gyroscope and an FM resonant...
8793618 Launching of multiple dashboard sets that each correspond to different stages of a multi-stage medical process  
A robust window pane display system and method for coordinating window pane displays in the form of dashboards to assist nurses and doctors in the treatment of a medical patient based upon various...
8791258 Pro-fluorescent probes  
The present invention provides a novel class of pro-fluorescent probes for reactive oxygen species (ROS). One exemplary probe is mitochondria peroxy yellow 1 (MitoPY1), a new type of flurophore for...
8791219 Rapidly crosslinkable adhesives for biomedical applications  
The present inventions are directed to novel medical adhesives and their use, for example, in biomedical applications. These compositions and applications allow for improved adhesion with and...
8791166 Producing methanol and its products exclusively from geothermal sources and their energy  
The invention provides a method for producing methanol and its products exclusively from a geothermal source as the sole source material also using the needed energy from the geothermal energy...
8791092 Molecular tweezers for the treatment of amyloid-related diseases  
This invention provides novel compositions to inhibit the aggregation of amyloid proteins. In various embodiments the compositions comprise a molecular tweezers that binds lysine and/or arginine...
8791062 Skin permeating and cell entering (SPACE) peptides and methods of use thereof  
The present disclosure provides peptides and peptide compositions, which facilitate the delivery of an active agent or an active agent carrier wherein the compositions are capable of penetrating...
8791000 Planar nonpolar group-III nitride films grown on miscut substrates  
A nonpolar III-nitride film grown on a miscut angle of a substrate, in order to suppress the surface undulations, is provided. The surface morphology of the film is improved with a miscut angle...
8790943 (Al,Ga,In)N diode laser fabricated at reduced temperature  
A method of fabricating an (Al,Ga,In)N laser diode, comprising depositing one or more III-N layers upon a growth substrate at a first temperature, depositing an indium containing laser core at a...
8790655 Conjugates of synthetic TLR agonists and uses therefor  
The invention provides TLR agonists and conjugates thereof useful in vaccines and to prevent, inhibit or treat a variety of disorders including pathogen infection and asthma.
8790542 Compositions and methods useful for ionic liquid treatment of biomass  
The present invention provides for novel compositions and methods for recycling or recovering ionic liquid used in IL pretreated cellulose and/or lignocellulosic biomass (LBM).
8790281 Method of thermal treatment of myolysis and destruction of benign uterine tumors  
A high-power ultrasound heating applicator for minimally-invasive thermal treatment of uterine fibroids or myomas. High-intensity interstitial ultrasound, applied with minimally-invasive...
US20140207493 SYSTEMS AND METHODS FOR MISSING DATA IMPUTATION  
Congestive heart failure (CHF) is a leading cause of death in the United States. WANDA is a wireless health project that leverages sensor technology and wireless communication to monitor the health...
US20140207170 Venous Modulation Of Collateral Perfusion of Cerebral Ischemia  
A patient in whom blood diversion due to cerebral venous steal is present, and abolishment of the cerebral venous steal is indicated, is treated by increasing the cerebral venous pressure in the...
US20140206763 PHENYLBUTYRATE FOR TREATMENT OF SPORADIC INCLUSION-BODY MYOSITIS AND DISORDERS RELATING TO AUTOPHAGY IMPAIRMENT OR AMYLOID BETA 42 ACCUMULATION  
Disclosed is a method of improving lysosomal activity in a patient in need thereof including administering to the patient an effective amount of phenylbutyrate, preferably 4-phenylbutyrate in the...
US20140206596 Design of pH-Sensitive Oligopeptide Complexes For Drug Release Under Mildly Acidic Conditions  
The present invention discloses a design for a molecular delivery vehicle capable of delivering a molecular payload to a target cell and its intracellular compartments. Also disclosed are highly...