Sign up

Patents and Patent Applications from University of California System


Match Document Document Title
8889414 Semiconductor nanocrystal-based phagokinetic tracking  
Methods for determining metabolic properties of living cells through the uptake of semiconductor nanocrystals by cells. Generally the methods require a layer of neutral or hydrophilic semiconductor...
8889156 Calcium-binding agents induce hair growth and/or nail growth  
This invention provides novel methods for inducing hair growth and/or inhibiting hair loss and/or inducing nail growth in a mammal. In various embodiments the methods involve administering, e.g.,...
8889140 Compositions and methods for tissue repair  
The present invention provides compositions and methods for targeting an extracellular matrix derived (EMD) peptide predominantly to an injured tissue, as opposed to an uninjured tissue in vivo....
US20140336755 TUBULAR SCAFFOLD FOR FABRICATION OF HEART VALVES  
A tubular braided mesh scaffold for fabrication of heart valves is described. The tubular braided scaffold can be formed of a shape memory metal, such as Nitinol, and pinched or pressed to form a...
US20140336367 RECOMBINANT NEL-LIKE (NELL) PROTEIN PRODUCTION  
The present invention provides a method and system for producing a NELL protein. The method and system comprise a CELL encoding a NELL protein or peptide and a non-insect secretory signal peptide.
US20140336110 Modified Mini-Hepcidin Peptides and Methods of Using Thereof  
Disclosed herein are peptides which exhibit hepcidin activity and methods of making and using thereof.
US20140336064 MULTIVOLUME DEVICES, KITS AND RELATED METHODS FOR QUANTIFICATION AND DETECTION OF NUCLEIC ACIDS AND OTHER ANALYTES  
Provided are devices comprising multivolume analysis regions, the devices being capable of supporting amplification, detection, and other processes. Also provided are related methods of detecting...
US20140335145 BIOMATERIALS AND IMPLANTS FOR ENHANCED CARTILAGE FORMATION, AND METHODS FOR MAKING AND USING THEM  
The invention provides products of manufacture, e.g., biomaterials and implants, for cartilage maintenance and/or formation in-vivo, in-vitro, and ex-vivo, using nanotechnology, e.g., using...
US20140335063 DELIVERY METHODS AND COMPOSITIONS FOR NUCLEASE-MEDIATED GENOME ENGINEERING  
Disclosed herein are methods and compositions for delivery of engineered nucleases and donor molecules into the genome of a cell.
US20140335045 bFGF-POLYMER CONJUGATES, METHODS FOR MAKING THE SAME AND APPLICATIONS THEREOF  
A heparin mimicking polymer, its conjugate with bFGF, and method of making and using the same are disclosed. In particular, described herein are conjugates of biologic agents (e.g., bFGF) and...
US20140334007 Optical Element Stacks for the Direction of Light  
Provided herein are devices and associated methods for the direction of light, e.g. sunlight. The devices may comprise various stacked optical elements, including wedge prisms and angled-facet...
US20140333933 Localized Surface Plasmon Resonance Mercury Detection System and Methods  
A mercury detection system that includes a flow cell having a mercury sensor, a light source and a light detector is provided. The mercury sensor includes a transparent substrate and a submonolayer...
US20140333373 SHARP PROGRAMMABLE FILTERS USING PERIODICALLY TIME-VARYING COMPONENTS  
A method and apparatus for selective programmable filtering using analog circuits with time-varying components (e.g., resistances, capacitances) is presented. An analog front end receives an...
US20140332783 Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexes of lr  
The invention provides emissive materials and organic light emitting devices using the emissive materials in an emissive layer disposed between and electrically connected to an anode and a cathode....
US20140332383 FREE-STANDING MICROFLUIDIC GEL ELECTROPHORESIS DEVICES AND METHODS  
Provided are devices that include a support, a free-standing polymeric separation medium associated with the support and configured to separate a sample along a directional axis, and a...
US20140332382 Two-Dimensional Microfluidic Devices and Methods of Using the Same  
Microfluidic devices and methods for using the same are provided. Embodiments include microfluidic devices that have a first separation region configured to separate a sample along a first...
US20140332381 FASTER RESISTIVE-PULSE SENSING TOGETHER WITH PHYSICAL AND MECHANICAL CHARACTERIZATION OF PARTICLES AND CELLS  
A method for multiplex characterization of individual particles by their size, shape, mechanical properties (deformability), and chemical affinity to recognition agents. The analysis can be...
US20140332187 TITANIUM-BASED THERMAL GROUND PLANE  
Titanium-based thermal ground planes are described. A thermal ground plane in accordance with the present invention comprises a titanium substrate comprising a plurality of pillars, wherein the...
8885860 Direct drive micro hearing device  
A device and methods are provided for a hearing device. In one embodiment, a hearing device includes a microphone to receive sound, an interactive tip and actuator. The actuator can include an...
8884617 Magnetic particle imaging devices and methods  
A magnetic particle imaging device is provided. The device includes a magnetic field source configured to produce a magnetic field having a non-saturating magnetic field region, an excitation...
8883502 Expandable cell source of neuronal stem cell populations and methods for obtaining and using them  
The invention provides methods for obtaining neural stem cells from a mammalian embryonic or inducible pluripotent stem cell population comprising culturing mammalian embryonic or inducible...
8883497 Human myeloid derived suppressor cell cancer markers  
Provided herein are methods for determining the presence of cancer (malignant versus benign), monitoring the progression of cancer, monitoring cancer relapse, monitoring the response to cancer...
8883428 Methods to determine atherosclerosis regression, plaque stabilization and cardiovascular risk  
Provided herein are compositions and methods for examining the progression, regression or risk of individuals at risk for developing coronary artery disease (CAD).
8883214 Implantable delivery vehicle for ocular delivery of muscarinic antagonists  
The present invention provides compositions and methods for treating ocular disorders such as myopia.
8883155 Methods for treating hematopoietic malignancies  
The present invention relates to methods for treating neoplasias in a mammalian subject. In particular, the invention provides methods for treating lymphomas, including forms of non-Hodgkin...
8883014 Monolithically formed EWOD device and method of making the same  
A monolithic fabrication method of parallel-plate electrowetting-on-dielectric (EWOD) chips for digital microfluidics of picoliter droplets is disclosed. Instead of assembling a second substrate to...
8882935 Fabrication of nonpolar indium gallium nitride thin films, heterostructures, and devices by metalorganic chemical vapor deposition  
A method for the fabrication of nonpolar indium gallium nitride (InGaN) films as well as nonpolar InGaN-containing device structures using metalorganic chemical vapor deposition (MOVCD). The method...
US20140331359 TRANSGENIC PLANTS COMPRISING A MUTANT PHYTOCHROME AND SHOWING ALTERED PHOTOMORPHOGENESIS  
This invention pertains to the discovery of mutant phytochromes that when introduced into a plant alter the photomorphogenic properties of that plant. In certain embodiments transfection of plants...
US20140330374 IMPLANTING OVERSIZED OBJECTS INTO SURGICAL BEDS  
The present invention relates to a deformable object to be implanted into a surgical site (exemplified by but not limited to a cornea lenticule, e.g., that could be native corneal tissue or a...
US20140329889 CYCLIC DI-NUCLEOTIDE INDUCTION OF TYPE I INTERFERON  
Methods and compositions are provided for increasing the production of a type I interferon (IFN) in a cell. Aspects of the methods include increasing the level of a 2′-5′ phosphodiester linkage com...
US20140329863 NOVEL ANTIPRION COMPOUNDS  
Described herein are novel compositions and methods of treatment addressing diseases such as neurodegenerative diseases, including prion diseases and Alzheimer's disease.
US20140329705 SALIVA COLLECTION, PROCESSING, STABILIZATION, AND STORAGE METHOD  
Provided herein is an all-in-one saliva collection apparatus that collects saliva to allow for the filtration of saliva in order to separate saliva components, such as extracellular proteins and...
US20140329326 SYNTHETIC GENE CLUSTERS  
Methods for making synthetic gene clusters are described.
US20140329288 IN VIVO CONVERSION OF LIGHT ENERGY INTO HYDROGEN GAS  
The present disclosure provides isolated phototrophic cells for producing hydrogen and methods for use thereof. The methods involve inducing endo-hydrogenase expression in the phototrophic cells...
US20140329274 METABOLIC FLUX MEASUREMENT, IMAGING AND MICROSCOPY  
Provided herein are methods for measuring molecular flux rates of molecules of interest in a tissue sample in spatially-organized manner and generating output (e.g., an image, a heat map, a contour...
US20140329221 REPERFUSION PROTECTION SOLUTION AND USES THEREOF  
In various embodiments a reperfusion protection solution (RPS) is provided along with methods of use thereof. Illustrative reperfusion protection solutions include, but are not limited to a buffer;...
US20140329089 TEMPLATED SYNTHESIS OF METAL NANORODS IN SILICA NANOTUBES  
A method of preparing a metal nanorod. The method includes seeding a metal nanoparticle within the lumen of a nanotube, and growing a metal nanorod from the seeded metal nanoparticle to form a...
US20140328863 Induction of Differential Stress Resistance and Uses Thereof  
This invention relates to methods of inducing differential stress resistance in a subject with cancer by starving the subject for a short term, administering a cell growth inhibitor to the subject,...
US20140328862 HUMAN IMMUNODEFICIENCY VIRUS NEUTRALIZING ANTIBODIES AND METHODS OF USE THEREOF  
The invention provides broadly neutralizing antibodies directed to epitopes of Human Immunodeficiency Virus, or HIV. The invention further provides compositions containing HIV antibodies used for...
US20140328851 Cholesterol Ester Transfer Protein (CETP) Inhibitor Polypeptide Antibodies for Prophylactic and Therapeutic Anti-Atherosclerosis Treatments  
Herein are described two antibodies that can inhibit CETP-lipoproteins interaction and CETP activity. Presently described are an antibody or fragment thereof capable of specifically binding to an...
US20140328847 MITIGATION OF DISEASE BY INHIBITION OF GALECTIN-12  
It has now been discovered that mice with an ablated galectin-12 gene exhibit enhanced fat mobilization (lipolysis), have reduced adipose tissue mass, improved insulin sensitivity and glucose...
US20140327748 RENDERING FOR AN INTERACTIVE 360 DEGREE LIGHT FIELD DISPLAY  
An interactive, autostereoscopic system for displaying an object in 3D includes a mirror configured to spin around a vertical axis when actuated by a motor, a high speed video projector, and a...
US20140327691 HIGH DYNAMIC RANGE IMAGE EDITING  
A high dynamic range image editing system for editing an image file having pixels spanning a first range of light intensity levels in an image editing system that only displays differences in the...
US20140326801 SYSTEM AND METHODS FOR MONITORING LEAF TEMPERATURE FOR PREDICTION OF PLANT WATER STATUS  
An apparatus and system for monitoring plant leaves to determine plant water needs and an automated variable-rate irrigation management system which can implement precision irrigation by taking...
US20140326311 METAL-CHALOGENIDE PHOTOVOLTAIC DEVICE WITH METAL-OXIDE NANOPARTICLE WINDOW LAYER  
A metal-chalcogenide photovoltaic device includes a first electrode, a window layer spaced apart from the first electrode, and a photon-absorption layer between the first electrode and the window...
8880385 Method and system for modeling bone structure from collagen bundle orientations  
The present invention relates to the characterization of human bone microstructure that is applicable to methods of characterizing and predicting fracture initiation, propagation, and arrest. These...
8879588 Method and device for fast tuning of optical sources  
A method and device are provided for fast, continuous tuning of an optical source. A first pump signal with a first pump frequency is input into a mixer along with a first seed signal having a...
8879290 Unified control of single and three-phase power converters  
Provided herein are unified control methods and implementations for controlling single and three-phase power converters. In an exemplary embodiment, a unified controller is provided that can be...
8878464 Laser accelerator driven particle brachytherapy devices, systems, and methods  
A laser accelerator driven electronic brachytherapy system, device, and method for particle based treatment of a tumor or other human diseases and conditions.
8878249 Method for heteroepitaxial growth of high channel conductivity and high breakdown voltage nitrogen polar high electron mobility transistors  
A method for growing high mobility, high charge Nitrogen polar (N-polar) or Nitrogen face (In,Al,Ga)N/GaN High Electron Mobility Transistors (HEMTs). The method can provide a successful approach to...