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Patents and Patent Applications from University of California System


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8772020 Fermentation system having strainer assembly  
A fermentation system for production of biogas from solid organic material, the system including at least one fermentation reactor. The fermentation reactor includes a vessel (37) for housing a...
8771940 Array for detecting microbes  
The present embodiments relate to an array system for detecting and identifying biomolecules and organisms. More specifically, the present embodiments relate to an array system comprising a...
8771403 Method and system for capturing carbon dioxide and/or sulfur dioxide from gas stream  
The present invention provides a system for capturing CO2 and/or SO2, comprising: (a) a CO2 and/or SO2 absorber comprising an amine and/or amino acid salt capable of absorbing the CO2 and/or SO2 to...
8771388 Method to produce methane rich fuel gas from carbonaceous feedstocks using a steam hydrogasification reactor and a water gas shift reactor  
A method for producing high levels of methane based on a combination of steam hydrogasification and a shift reactor is provided. Hydrogen produced by the shift reactor can be recycled back into the...
8771347 Accommodating intraocular lens  
Systems, devices, and methods are presented for a prosthetic injectable intraocular lens. One or more silicone elastomeric patches located outside the optical path on the anterior side but away...
8771298 Treatment of sphincter dysfunction  
A dysfunctional sphincter muscle may be treated by shortening the muscle to plicate it and restore its functionality. Plicating the sphincter muscle as described effectively shortens the muscle and...
US20140188200 SYSTEMS, DEVICES AND METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS AND CONDITIONS  
The present disclosure relates to methods, devices, and systems used for the treatment of and/or promoting recovery from various neurological disorders and conditions, including epilepsy and other...
US20140188072 SYSTEM AND METHOD FOR CLOSED-LOOP PATIENT-ADAPTIVE HEMODYNAMIC MANAGEMENT  
A system and method for patient-adaptive hemodynamic management is described. One embodiment includes a system for hemodynamic management including transfusion, volume resuscitation with...
US20140188009 CUSTOMIZABLE ACTIVITY TRAINING AND REHABILITATION SYSTEM  
A system may include a calibration module that measures a range of limb and trunk movements made by a human subject during a calibration phase of the system. A customization module may customize...
US20140187998 DEVICES AND TREATMENT METHODS FOR VASCULAR EYE DISEASES  
A method of treating ROP, the method comprising providing a light source emitting light with a wavelength of about 490 nra, exposing an infant's eye to the light, and monitoring the vascularization...
US20140187607 METHODS OF MODULATING COMPLIANCE OF THE TRABECULAR MESHWORK  
The present invention relates to method, system, and composition for modulating the compliance of the trabecular meshwork, which may provide treatment to glaucoma.
US20140187523 TOPICAL CORTICOSTEROIDS FOR THE TREATMENT OF INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT  
Provided herein are methods for preventing or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract, for example, those...
US20140187441 AMPLIFICATION OF CYP24 AND USES THEREOF  
This invention pertains to the discovery that an amplification of the CYP24 gene or an increase in CYP24 activity is a marker for the presence of, progression of, or predisposition to, a cancer...
US20140187436 NANOPLASMONIC MOLECULAR RULER FOR NUCLEASE ACTIVITY AND DNA FOOTPRINTING  
This invention provides a nanoplasmonic molecular ruler, which can perform label-free and real-time monitoring of nucleic acid (e.g., DNA) length changes and perform nucleic acid footprinting. In...
US20140186838 MOLECULAR FLUX RATES THROUGH CRITICAL PATHWAYS MEASURED BY STABLE ISOTOPE LABELING IN VIVO, AS BIOMARKERS OF DRUG ACTION AND DISEASE ACTIVITY  
The methods described herein enable the evaluation of compounds on subjects to assess their therapeutic efficacy or toxic effects. The target of analysis is the underlying biochemical process or...
US20140186500 DEVICES AND METHODS FOR REDUCING THE MICROBIAL LOAD ON AN OBJECT USING A UV LIGHT SOURCE  
The present disclosure provides devices for reducing the microbial load on objects (e.g., edible plant matter). In certain aspects, the devices include a UV light source and at least a portion of a...
US20140186436 ORAL DELIVERY OF ENZYMES BY NANOCAPSULES FOR TARGETED METABOLISM OF ALCOHOL OR TOXIC METABOLITES  
The invention disclosed herein includes nanocomplexes that are designed include enzymes that have complementary functional attributes and methods for using these nanocomplexes. Illustrative...
US20140186426 CATALYTIC DELIVERY NANOSUBSTRATES (CDNS) FOR HIGHLY EFFICIENT DELIVERY OF BIOMOLECULES  
This invention relates, e.g., to a molecular delivery system comprising A. a substrate having a nanostructured surface region which comprises a plurality of nanostructures and, covalently attached...
US20140186392 Interferon-ß Production Modulating Listeria Strains and Methods for Using Same  
Mutant Listeria bacteria that modulate interferon-B production are provided. The subject bacteria are characterized by having a mutation in a gene chosen from a TetR gene, a LadR gene, a VirR gene,...
US20140186309 COMPOSITIONS AND METHODS FOR TREATING RETINAL DISEASES  
Disclosed herein are compositions and methods for treating, ameliorating or preventing a retinal disease or condition; improving a photopic (day light) vision; for improving correcting visual...
US20140186290 NANOPARTICLE BASED THERAPY FOR DISPERSING MUCIN  
There are provided compositions and methods to disperse mucin and/or actin using nanoparticles wherein the average diameter of the nanoparticles is less than about 1000 nm.
US20140186273 Chitosan -Amelogenin Hydrogel for In Situ Enamel Growth  
A composition for re-constructing enamel-coated substrates such as a tooth which includes an amelogenin, chitosan, and water. The composition may also include compounds providing calcium and...
US20140183579 MISCUT SEMIPOLAR OPTOELECTRONIC DEVICE  
A method for improved growth of a semipolar (Al,In,Ga,B)N semiconductor thin film using an intentionally miscut substrate. Specifically, the method comprises intentionally miscutting a substrate,...
8769511 Dynamic incremental compiler and method  
A virtual machine executive (VME) system operating on a target platform that includes a virtual machine monitor (VMM) and a dynamic compiler, in particular, a trace compiler (TC). System...
8768274 Cellular phone with integrated FM radio and remote low noise amplifier  
A cellular phone comprises a first wireless transceiver that receives radio frequency (RF) signals, which include frequency modulated (FM) signals that have been tuned by a remote device. An FM...
8767908 Exact and approximate rebinning of time-of-flight PET positron emission tomography data  
A technique for processing of data from time-of-flight (TOF) PET scanners. The size of TOF PET data may be reduced without significant loss of information through a process called rebinning. The...
8766754 Concave nanomagnets with widely tunable anisotropy  
A nanomagnet having widely tunable anisotropy is disclosed. The disclosed nanomagnet is a magnetic particle with a convex shape having a first magnetically easy axis. The convex shape is modified...
8766341 Epitaxial growth of single crystalline MgO on germanium  
The embodiments disclosed herein relate to growth of magnesium-oxide on a single crystalline substrate of germanium. The embodiments further describes a method of manufacturing and crystalline...
8766296 Highly efficient gallium nitride based light emitting diodes via surface roughening  
A gallium nitride (GaN) based light emitting diode (LED), wherein light is extracted through a nitrogen face (N-face) of the LED and a surface of the N-face is roughened into one or more hexagonal...
8765484 Optically encoded particles  
The invention concerns a particle having a code embedded in its physical structure by refractive index changes between different regions of the particle. In preferred embodiments, a thin film...
8765459 Apparatus and methods for manipulation and optimization of biological systems  
The invention provides systems and methods for manipulating biological systems, for example to elicit a more desired biological response from a biological sample, such as a tissue, organ, and/or a...
8765455 Chip-based droplet sorting  
A non-contact system for sorting monodisperse water-in-oil emulsion droplets in a microfluidic device based on the droplet's contents and their interaction with an applied electromagnetic field or...
8765410 Methods and compositions for improving sugar transport, mixed sugar fermentation, and production of biofuels  
The present disclosure relates to host cells containing a recombinant polynucleotide encoding a polypeptide where the polypeptide transports cellodextrin into the cell. The present disclosure...
8765403 Use of synthetic scaffolds for the production of biosynthetic pathway products  
The present invention provides methods of producing a product or product precursor of a biosynthetic pathway in a genetically modified host cell. The present invention also provides genetically...
8765373 Sensor and method for detection of a target substance  
A method of detecting a target substance includes providing a number of molecular tethers at a channel surface of a sensor such that at least some of a plurality of beads, as a result of a...
8765171 Methods and compositions for liposomal formulation of antigens and uses thereof  
The present invention relates to liposomal vaccine compositions, methods for the manufacture thereof, and methods for the use thereof to stimulate an immune response in an animal. These...
8765147 Endophytic fungi from Pteromischum sp. plant, compounds and methods of use  
The present disclosure relates to endophytic fungi from higher plants such as a Pteromischum sp. plant, and to extracts and compounds from such fungi that have desirable biological activities, such...
8764708 MEMS device and method for delivery of therapeutic agents  
Embodiments of an implantable device for delivering a therapeutic agent to a patient include a reservoir configured to contain a liquid comprising the therapeutic agent, and a cannula in fluid...
8764666 Ultrasound guided optical coherence tomography, photoacoustic probe for biomedical imaging  
An imaging probe for a biological sample includes an OCT probe and an ultrasound probe combined with the OCT probe in an integral probe package capable of providing by a single scanning operation...
US20140180998 EFFICIENT SEARCHING OF STATIONARY DATASETS  
A saliency function is computed to indicate the saliency of each of a plurality of data points in a dataset. For each local maximum in the saliency function, a segment of the dataset is inserted...
US20140180399 MESH ENCLOSED TISSUE CONSTRUCTS  
Described is a heart valve leaflet manufactured from a mesh material. The mesh material may have an ability to capture circulatory/stationary/migratory cells of the body to become biologically...
US20140180395 BIOACTIVE SPIRAL COIL COATING  
An endovascular spiral coil coating and methods of making and using the same.
US20140180361 NEUROSTIMULATOR  
A neurostimulator device for use with groups (e.g., more than four groups) of electrodes. The neurostimulator may include a stimulation assembly configured to deliver different stimulation to each...
US20140180085 Renal Injury Inhibiting Devices, Systems, and Methods Employing Low-Frequency Ultrasound or Other Cyclical Pressure Energies  
Improved devices, systems, and methods treatment of patients can be used to help mitigate injury to the kidneys by applying cyclical mechanical pressure energy at low intensities. The energy often...
US20140180065 FIDUCIARY MARKERS AND METHODS OF PLACEMENT  
The invention relates to the field of radiation oncology, specifically the use of novel radio-opaque fiduciary markers which resist migration within tissues, which may be implanted in the body and...
US20140180052 NEURAL RECORDING SYSTEM  
A neuron recording system was provided. By using the gain-boosted topology, the amplifier input impedance can be increased while simultaneously reducing the noise. The system can be configured to...
US20140179616 PEPTIDES THAT STIMULATE SUBCUTANEOUS ADIPOGENESIS  
Peptides of 5 to 14 amino acids in length that stimulate subcutaneous adipogenesis and uses thereof are provided.
US20140179598 SOMATOSTATIN ANALOGS WITH INHIBITORY ACTIVITY TO GROWTH HORMONE RELEASE  
Provided are therapeutic and diagnostic somatostatin analogs including radiotherapeutic and radiodiagnostic reagents, and methods of making and use thereof.
US20140179046 SEMICONDUCTOR NANOCRYSTAL PROBES FOR BIOLOGICAL APPLICATIONS AND PROCESS FOR MAKING AND USING SUCH PROBES  
A semiconductor nanocrystal compound and probe are described. The compound is capable of linking to one or more affinity molecules. The compound comprises (1) one or more semiconductor nanocrystals...
US20140178865 RAPID, MASSIVELY PARALLEL SINGLE-CELL DRUG RESPONSE MEASUREMENTS VIA LIVE CELL INTERFEROMETRY  
A central question in cancer therapy is how individual cells within a population of tumor cells respond to drugs designed to arrest their growth. However, the absolute growth of cells, their change...