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Patents and Patent Applications from University of California System


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US20140294140 RADIOGRAPHIC PHANTOM APPARATUSES  
There is provided a radiographic phantom for inter alia mimicking specific anatomical parts in a computerized tomography scan. Methods are provided for a variety of purposes including detecting a...
US20140293683 MAGNETO-RESISTIVE EFFECT ELEMENT  
[PURPOSE] According to the invention there is provided a magneto-resistive effect element having a larger magneto-resistive ratio than in the prior art.[SOLUTION MEANS]The magneto-resistive effect...
US20140293028 MULTI VIEW SYNTHESIS METHOD AND DISPLAY DEVICES WITH SPATIAL AND INTER-VIEW CONSISTENCY  
An embodiment of the invention is a method that provides common data and enforces multiple view consistency. In a preferred embodiment, a coordinate alignment matrix is generated after initial...
US20140292517 SYSTEM AND METHODS FOR GENERATING PREDICTIVE COMBINATIONS OF HOSPITAL MONITOR ALARMS  
Systems and methods are disclosed for monitoring data associated with a plurality of physiological characteristics of a patient, comprising: the methods include generating a set of super-alarm...
US20140292420 HIGH-SPEED CMOS RING VOLTAGE CONTROLLED OSCILLATOR WITH LOW SUPPLY SENSITIVITY  
High-speed CMOS ring voltage controlled oscillators with low supply sensitivity have been disclosed. According to one embodiment, a CML ring oscillator comprises a CML negative impedance...
US20140291694 PLANAR NONPOLAR GROUP-III NITRIDE FILMS GROWN ON MISCUT SUBSTRATES  
A nonpolar III-nitride film grown on a miscut angle of a substrate, in order to suppress the surface undulations, is provided. The surface morphology of the film is improved with a miscut angle...
US20140291609 JUNCTIONLESS SEMICONDUCTOR LIGHT EMITTING DEVICES  
A junctionless light emitting device comprises a field emitter cathode, and a light emitting semi-conductor material sandwiched between an ohmic contact (OC) that faces the injected electrons and a...
US20140291296 NANOMATERIALS FABRICATED USING SPARK EROSION AND OTHER PARTICLE FABRICATION PROCESSES  
Methods, systems, and devices are disclosed for fabricating clean, oxidation-free nanoparticles of electrically conducting metals and alloys using spark erosion techniques. In one aspect, a method...
US20140290987 SOLUTION PROCESSED NANOPARTICLE-NANOWIRE COMPOSITE FILM AS A TRANSPARENT CONDUCTOR FOR OPTO-ELECTRONIC DEVICES  
An electro-optic device includes a substructure, a layer of nanowires deposited on the substructure so as to form a network of nanowires having electrically connected junctions at overlapping...
US20140290737 THIN FILM VLS SEMICONDUCTOR GROWTH PROCESS  
A composition comprising a substrate, a polycrystalline III-V semiconductor layer, and an oxide layer disposed above the polycrystalline III-V semiconductor layer is described. A growth method that...
8849581 Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activity  
The methods described herein enable the evaluation of compounds on subjects to assess their therapeutic efficacy or toxic effects. The target of analysis is the underlying biochemical process or...
8847606 Method and system for assessing insulation deterioration in live underground power cables  
A method for assessing insulation deterioration in a live underground power cable may include, in one embodiment, attaching a coupling device to a live underground power cable and using the...
8847592 Techniques for magnetic particle imaging  
A magnetic particle imaging apparatus includes magnets [106,107] that produce a gradient magnetic field having a field free region (FFR), excitation field electromagnets [102,114] that produce a...
8847476 Electron injection nanostructured semiconductor material anode electroluminescence method and device  
Embodiments of the invention include methods and devices for producing light by injecting electrons from field emission cathode across a gap into nanostructured semiconductor materials, electrons...
8847313 Transparent electronics based on transfer printed carbon nanotubes on rigid and flexible substrates  
Methods and devices for transparent electronics are disclosed. According to an embodiment, transparent electronics are provided based on transfer printed carbon nanotubes that can be disposed on...
8846932 Small molecules modulator of epigenetic regulation and their therapeutic applications  
Disclosed are methods and compositions for modulating the function of transcription factors, especially transcription factors that recruit epigenetic regulators (histone modifying enzymes) to...
8846866 Aldehyde tags, uses thereof in site-specific protein modification  
The invention features compositions and methods for site-specific modification of proteins by incorporation of an aldehyde tag. Enzymatic modification at a sulfatase motif of the aldehyde tag...
8846770 Controlled release aural pressure modulator compositions and methods for the treatment of OTIC disorders  
Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with aural pressure modulating agent compositions and formulations administered locally to an...
8846697 Purine analogs  
The present invention provides purine analog compounds, as well as compositions and methods of using them, for example, to prevent or treat various diseases and disorders in human and non-human...
8846643 Phosphonates with reduced toxicity for treatment of viral infections  
There are provided, inter alia, acyclic nucleoside phosphonate compounds having reduced toxicity and enhanced antiviral activity, and pharmaceutically accepted salts and solvates thereof. There are...
8846629 Id-1 and Id-2 genes and products as therapeutic targets for treatment of breast cancer and other types of carcinoma  
A method for treatment and amelioration of breast, cervical, ovarian, endometrial, squamous cells, prostate cancer and melanoma in a patient comprising targeting Id-1 or Id-2 gene expression with a...
8846572 Use of 9-beta-D-adenosine to increase crop production  
Described are compositions and methods to increase bud break in order to increase aspects of one or both of plant vegetative and reproductive growth, by use of a natural metabolite. In particular,...
8846066 Methods and related compositions for reduction of fat and skin tightening  
Compositions and methods useful in the reduction of localized fat deposits and tightening of loose skin in subjects in need thereof using pharmacologically active detergents are disclosed. The...
8845999 Tracers for monitoring the activity of sodium/glucose cotransporters in health and disease  
Radiolabeled tracers for sodium/glucose cotransporters (SGLTs), their synthesis, and their use are provided. The tracers are methyl or ethyl pyranosides having an equatorial hydroxyl group at...
8845554 Method and apparatus for quantitative assessment of neuromotor disorders  
The present invention relates to methods and apparatus for quantitative assessment of neuromotor disorders using sensors and analyzing the data collected from the sensors to determine if a patient...
8844369 Concentration independent modulation of local micromechanics in a fibrin gel  
An apparatus and method for providing a gradient strain to an extracellular matrix to induce mechanotransduction. The gradient strain can be produced by adhering the extracellular matrix to a post...
US20140288643 DEVICE TO STORE AND INJECT CORNEAL GRAFT  
Devices and methods for storing and injecting a corneal tissue graft are disclosed herein. In one embodiment, an apparatus includes a tissue container and an adaptor configured to be coupled to the...
US20140288544 IMPLANTABLE THERMAL TREATMENT METHOD AND APPARATUS  
A long-term implantable ultrasound therapy system and method is provided that provides directional, focused ultrasound to localized regions of tissue within body joints, such as spinal joints. An...
US20140288515 MICROPATTERNED TEXTILE FOR FLUID TRANSPORT  
This invention includes the implementation of several unconventional droplet manipulations on a superhydrophobic-patterned surface microfluidic platform, which may be applied to automated...
US20140288421 GAS VESICLE ULTRASOUND CONTRAST AGENTS AND METHODS OF USING THE SAME  
Provided are ultrasound imaging methods that include administering to a subject a contrast agent that includes a plurality of collapsible gas vesicles, obtaining ultrasound data of a target site of...
US20140288398 COMPOSITIONS AND DEVICES FOR THE DETECTION OF BIOMARKERS IN THE GASTROINTESTINAL TRACT AND METHODS FOR MAKING AND USING THEM  
In alternative embodiments, the invention provides compositions such as devices, pills, beads, capsules, products of manufacture, particles, microparticles, nanoparticles, gels, liquid gels, liquid...
US20140288397 SEM SCANNER SENSING APPARATUS, SYSTEM AND METHODOLOGY FOR EARLY DETECTION OF ULCERS  
A handheld, conforming capacitive sensing apparatus configured to measure Sub-Epidermal Moisture (SEM) as a mean to detect and monitor the formation of pressure ulcers. The device incorporates an...
US20140288170 META-SUBSTITUTED BIPHENYL PERIPHERALLY RESTRICTED FAAH INHIBITORS  
The present invention provides methods of making and using peripherally restricted inhibitors of fatty acid amide hydrolase (FAAH). The present invention provides compounds and compositions that...
US20140288150 DENDRONIZED POLYMERS FOR NUCLEIC ACID DELIVERY  
The disclosure provides for dendronized polymers, and the use of the polymers as carriers for the intracellular delivery of nucleic acids.
US20140288115 COMPOSITIONS AND METHODS FOR TREATING BRAIN CANCER  
It is discovered that noscapine is effective in treating temozolomide (TMZ)-resistant brain cancer. Provided are compositions and methods of treating brain cancer patients, in particular those that...
US20140288097 USE OF TRANSLATIONAL PROFILING TO IDENTIFY TARGET MOLECULES FOR THERAPEUTIC TREATMENT  
The present invention provides methods of identifying an agent or drug candidate molecule, validating a target, and identifying normalizing therapeutics that modulates translation, such as in an...
US20140288096 P13 KINASE ANTAGONISTS  
The present invention provides novel PI3-Kinase antagonists and methods of use thereof.
US20140288087 NICHE TARGETING OF QUIESCENT CANCER STEM CELLS  
The disclosure provides methods for determining the self-renewal potential of a cancer stem cell (CSC), or for predicting the drugability (susceptibility to a drug) of a CSC, and/or for predicting...
US20140288000 DUAL REACTIVITY POTENT KUNITZ INHIBITOR OF FIBRINOLYSIS  
Compositions and methods are disclosed that relate to novel plasmin-inhibiting polypeptides that are structural variants of a human TFPI-2 Kunitz-type proteinase first inhibitor domain (KD1). The...
US20140287994 PEPTIDES HAVING REDUCED TOXICITY THAT STIMULATE CHOLESTEROL EFFLUX  
The present invention provides a family of non-naturally occurring polypeptides having cholesterol efflux activity that parallels that of full-length apolipoproteins (e.g., Apo AI and Apo E), and...
US20140287961 ARRAY FOR DETECTING MICROBES  
The present embodiments relate to an array system for detecting and identifying biomolecules and organisms. More specifically, the present embodiments relate to an array system comprising a...
US20140287957 ISOTOPIC LABELING FOR THE MEASUREMENT OF GLOBAL PROTEIN LEVELS AND TURNOVER IN VIVO  
An entire complement or plurality of isotopically labeled amino acids are introduced into the diet of a test subject. Sufficient amounts of the isotopically labeled amino acids are provided to the...
US20140287497 Methods of Modulating Cold Sensory Perception  
The present invention relates to regulation of cold sensation and pain. More particularly, the present invention is directed to nucleic acids encoding a member of the transient regulatory protein...
US20140287426 ANTIBODY AND ANTIBODY MIMETIC FOR VISUALIZATION AND ABLATION OF ENDOGENOUS PROTEINS  
Provided are compositions and methods for labeling an endogenous protein, in particular, in a live cell, or for ablating an endogenous or target protein. The compositions relate to a fusion protein...
US20140287389 SYSTEMS AND METHODS FOR REAL-TIME ADAPTIVE THERAPY AND REHABILITATION  
Virtual reality-based adaptive systems and methods are disclosed for improving the delivery of physical therapy and rehabilitation. The invention comprises an interactive software solution for...
US20140286865 SYNTHETIC DIBLOCK COPOLYPEPTIDE HYDROGELS FOR USE IN THE CENTRAL NERVOUS SYSTEM  
This invention relates, e.g., to a composition suitable for administration to the central nervous system (CNS), comprising a block copolypeptide hydrogel, which comprises a biologically active...
US20140286367 NANOPILLAR PHOTONIC CRYSTAL LASERS  
A nanopillar photonic crystal laser includes a plurality of nanopillars and a support structure in contact with at least a portion of each of the nanopillars. Each nanopillar has an axial dimension...
US20140285272 Computer Aided Fabrication Systems  
A technique for implementing an clock tree distribution network having a clock buffer and a plurality of LC tanks that each take into \consideration local capacitance distributions and conductor...
US20140285061 THERMOMECHANICAL CYCLE FOR THERMAL AND/OR MECHANICAL ENERGY CONVERSION USING PIEZOELECTRIC MATERIALS  
A system for generating electrical energy includes a thermal source, an electric field source, a stress source, a piezoelectric component, and a cycle controller coupled to the thermal source, the...
US20140284207 FILTERS FOR BLOCKING MACROPARTICLES IN PLASMA DEPOSITION APPARATUS  
This disclosure provides systems, methods, and apparatus related to blocking macroparticles in deposition processes utilizing plasmas. In one aspect, an apparatus includes a cathode, a substrate...