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Patents and Patent Applications from University of California System


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US20150118604 METHOD FOR FABRICATION OF HIGH ASPECT RATIO TRENCHES AND FORMATION OF NANOSCALE FEATURES THEREFROM  
A process for forming trenches in a target material includes forming a masking layer onto the target material, where the masking layer comprises a material having high selectivity to a plasma etch...
US20150118319 PROTEOLYSIS-RESISTANT CAPSID OF CHIMERIC HEPATITIS E VIRUS AS AN ORAL DELIVERY VECTOR  
This invention provides a peptide/nucleic acid composition for oral/mucosal, dual-modal activation of immune protection systems.
US20150118287 SYSTEMIC DELIVERY AND REGULATED EXPRESSION OF PARACRINE GENES FOR CARDIOVASCULAR DISEASES AND OTHER CONDITIONS  
In alternative embodiments, the invention provides methods for treating, ameliorating or protecting (preventing) an individual or a patient against a disease, an infection or a condition responsive...
US20150118277 OXYSTEROL ANALOGUE OXY133 INDUCES OSTEOGENESIS AND HEDGEHOG SIGNALING AND INHIBITS ADIPOGENESIS  
This invention relates, e.g., to a synthetic compound, Oxy133, having the structure [Formula I] or a bioactive or pharmaceutical composition comprising Oxy133 and a pharmaceutically acceptable...
US20150118148 NOVEL OXIDE MATERIALS AND SYNTHESIS BY FLUORIDE/CHLORIDE ANION PROMOTED EXFOLIATION  
The present invention is directed to the synthesis of novel delaminated layered zeolite precursor materials prepared by fluoride/chloride anion-promoted exfoliation. The method comprises, for...
US20150118147 NOVEL OXIDE MATERIALS AND SYNTHESIS BY FLUORIDE/CHLORIDE ANION PROMOTED EXFOLIATION  
The present invention is directed to the synthesis of novel delaminated layered zeolite precursor materials prepared by fluoride/chloride anion-promoted exfoliation. The method comprises, for...
US20150118126 TRANSMISSION ELECTRON MICROSCOPE CELLS FOR USE WITH LIQUID SAMPLES  
This disclosure provides systems, methods, and devices related to transmission electron microscopy cells for use with liquids. In one aspect a device includes a substrate, a first graphene layer,...
US20150116553 MONOCENTRIC IMAGING  
Methods and systems are provided to enable the capture of large (e.g., Gigapixel) images with high image quality using optical imaging systems that have a small form factor. The disclosed systems...
US20150115220 (Al, In, Ga, B)N DEVICE STRUCTURES ON A PATTERNED SUBSTRATE  
A nitride light emitting diode comprising at least one nitride-based active region formed on or above a patterned substrate, wherein the active region is comprised of at least one quantum well...
US20150114267 CORROSION INHIBITING CEMENTITIOUS COMPOSITIONS  
Provided herein is a cementitious composition comprising a photoactivator, wherein the photoactivator is capable of converting NOx to NO2— or NO3— when exposed to ultraviolet (U.V.) or visible light.
PP25466 Walnut tree named ‘Solano’  
A new and distinct cultivar of walnut tree denominated ‘Solano’ is described. This new cultivar, ‘Solano’, comes into bearing young, with an excellent yield. ‘Solano’ forms jumbo-sized walnuts tha...
9020639 Multimodal dynamic robotic systems  
Robotic systems according to the invention include a frame or body with two or more wheels rotatably mounted on the frame or body and a motor for independently driving each wheel. A system...
9020002 Hybrid silicon laser-quantum well intermixing wafer bonded integration platform for advanced photonic circuits with electroabsorption modulators  
Photonic integrated circuits on silicon are disclosed. By bonding a wafer of compound semiconductor material as an active region to silicon and removing the substrate, the lasers, amplifiers,...
9019078 Surgical object tracking system  
A method and apparatus for identifying and tracking surgical objects is disclosed. More specifically, a method and apparatus for identifying and tracking surgical objects such as needles, scalpels,...
9018649 Method of producing nanopatterned articles, and articles produced thereby  
A nanopatterned surface is prepared by forming a block copolymer film on a miscut crystalline substrate, annealing the block copolymer film, then reconstructing the surface of the annealed block...
9018210 Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation  
Provided are substituted benzaldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions...
9018122 Nanostructures having crystalline and amorphous phases  
The present invention includes a nanostructure, a method of making thereof, and a method of photocatalysis. In one embodiment, the nanostructure includes a crystalline phase and an amorphous phase...
9017826 Visible/near-infrared porphyrin-tape/C60 organic photodetectors  
Porphyrin compounds are provided. The compounds may further comprise a fused polycyclic aromatic hydrocarbon or a fused heterocyclic aromatic. Fused polycyclic aromatic hydrocarbon s and fused...
9017773 Universal solution for growing thin films of electrically conductive nanostructures  
A method is described for depositing nanostructures, such as nanostructures of conducting polymers, carbon nanostructures, or combinations thereof. The process comprises placing the nanostructures...
9017766 Methods and devices comprising soluble conjugated polymers  
Methods, compositions and articles of manufacture involving soluble conjugated polymers are provided. The conjugated polymers have a sufficient density of polar substituents to render them soluble...
9017730 Compositions and uses of materials with high antimicrobial activity and low toxicity  
Improved synthetic copolypeptide antimicrobials contain cationic amino acid residues and may be based on a blocky sequence. These antimicrobials show low mammalian toxicity and may undergo directed...
US20150112884 Identifying Genetic Relatives Without Compromising Privacy  
Aspects of the invention include determining relatedness between genomes without compromising privacy. In one aspect, secure genome sketches of genomes can be made publicly available without...
US20150112652 METHODS FOR IDENTIFYING DRUG TARGETS BASED ON GENOMIC SEQUENCE DATA  
This invention provides a computational approach to identifying potential antibacterial drug targets based on a genome sequence and its annotation. Starting from a fully sequenced genome, open...
US20150112082 DIARYLHYDANTOIN COMPOUNDS  
The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
US20150111903 PHARMACEUTICAL FORMULATIONS COMPRISING NEUROTROPHIN MIMETICS  
Methods and compounds for treating neurodegenerative and other disorders. Included is the administering to a subject in need thereof an effective amount of a compound having binding specificity for...
US20150111892 ACID CERAMIDASE INHIBITORS AND THEIR USE AS MEDICAMENTS  
The present invention concerns, in a first aspect, compounds of Formula I as defined herein, pharmaceutically acceptable salts thereof and pharmaceutical compositions containing such compounds. The...
US20150111787 DIGITAL MICROFLUIDIC CHIPS FOR AUTOMATED HYDROGEN DEUTERIUM EXCHANGE (HDX) MS ANALYSIS  
Described herein is a digital microfluidic droplet generator (DMDG) and a microfluidic platform for processing material introduced into the DMDG. The combination is particularly suited for...
US20150111201 PORTABLE RAPID DIAGNOSTIC TEST READER AND METHODS OF USING THE SAME  
A portable rapid diagnostic test reader system includes a mobile phone having a camera and one or more processors contained within the mobile phone and a modular housing configured to mount to the...
US20150110897 Sperm Protein as a Detection Biomarker of Early Stage Ovarian Cancer  
This disclosure provides a method for determining if a patient is likely to, or not likely to, experience ovarian cancer utilizing SP17 as a biomarker. It also provides methods and therapies to...
US20150110771 ENZYMES AND METHODS FOR CLEAVING N-GLYCANS FROM GLYCOPROTEINS  
Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the...
US20150110761 EXPANSION OF ALLOANTIGEN-REACTIVE REGULATORY T CELLS  
The present disclosure relates generally to the manufacture of regulatory T cells (Tregs) for use in immunotherapy. In particular, the present disclosure relates to robust approaches for the...
US20150110738 METHODS AND COMPOSITIONS FOR GENERATING AND USING ALLOGENEIC SUPPRESSOR CELLS  
The present invention is directed to generating suppressor cells by treating naive T cells with a suppressor-inducing composition such as anti-CD3, anti-CD28, IL-2, TGF-β, or some combination ...
US20150110381 METHODS FOR DELINEATING CELLULAR REGIONS AND CLASSIFYING REGIONS OF HISTOPATHOLOGY AND MICROANATOMY  
Embodiments disclosed herein provide methods and systems for delineating cell nuclei and classifying regions of histopathology or microanatomy while remaining invariant to batch effects. These...
US20150109652 NANOSTRUCTURED TRANSPARENT CONDUCTING OXIDE ELECTROCHROMIC DEVICE  
The embodiments described herein provide an electrochromic device. In an exemplary embodiment, the electrochromic device includes (1) a substrate and (2) a film supported by the substrate, where...
US20150108451 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES  
A compound having a structure according to formula (I) is disclosed. In formula (I), Cu is a monovalent copper atom; *C is a carbene carbon; X1 and X2 are selected from alkyl, cycloalkyl, alkoxy,...
US20150108004 Multi-Layer Structures and Methods for Forming  
An electroplating method that includes: a) contacting a first substrate with a first article, which includes a substrate and a conformable mask disposed in a pattern on the substrate; b)...
US20150107582 SPECTRALLY SELECTIVE COATINGS FOR OPTICAL SURFACES  
Techniques, systems, devices and materials are disclosed for spectrally selective coatings for optical surfaces having high solar absorptivity, low infrared emissivity, and strong durability at...
US20150106993 ANATOMY SHADING FOR GARMENTS  
In one embodiment, a garment includes a garment substrate and a pattern formed on the substrate that emulates the contours of an ideally proportioned body so as to give observers the impression of...
9015853 Concealing access patterns to electronic data storage for privacy  
Methods and systems of concealing access patterns to data storage, such as within servers of a cloud computing environment are presented. Server data storage is securely partitioned into smaller...
9014253 Apparatus and method for detecting communications from multiple sources  
A method, apparatus, and computer program for detecting sequences of digitally modulated symbols transmitted by multiple sources are provided. A real-domain representation that separately treats...
9013860 Asymmetric hybrid supercapacitors based on nanotube nanowire composites  
An asymmetric supercapacitor includes a first structure and a second structure spaced apart from said second structure. One of the structures comprises an anode, and the other of the first and...
9012882 Graphene nanomesh and method of making the same  
A graphene nanomesh includes a sheet of graphene having a plurality of periodically arranged apertures, wherein the plurality of apertures have a substantially uniform periodicity and substantially...
9012455 Pharmaceutical compositions containing an indoyl isoquinoline containing compound and uses thereof  
Chronic myelogenous leukemia (CML), and in particular imatinib resistant CML is treated using compositions and methods in which a Rad51-inhibitor and a kinase inhibitor are administered. Most...
9012450 Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation  
Provided are substituted heteroaryl aldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions...
9012407 Therapies which act on neuropeptide S receptors  
Compositions and methods that act on Neuropeptide S receptors (NPSR) (also known as “TGR23” or “vasopressin receptor-related receptor 1 (VRR1)”) to cause desired effects in the bodies of human o...
9012193 Micro-bubble plate for patterning biological and non-biological materials  
Systems and methods are provided for patterning biological and non-biological material at specific sites on a plate, as well as growing three dimensional structures. Preferred embodiments comprise...
9012177 Methods and compositions for improving sugar transport, mixed sugar fermentation, and production of biofuels  
The present disclosure relates to host cells containing a recombinant polynucleotide encoding a polypeptide where the polypeptide transports cellodextrin into the cell. The present disclosure...
9012134 CD127 expression inversely correlates with FoxP3 and suppressive function of CD4+ Tregs  
The invention provides methods of isolating CD127lo/− immunosuppressive regulatory T cells which can be greatly enriched for FoxP3, methods of expanding the isolated cells, pharmaceutical c...
9011913 Use of functionalized magnetic nanoparticles in cancer detection and treatment  
The present invention provides methods of detecting a cancer cell in an individual, methods of grading a cancer, and methods of treating a cancer. The methods involve use of functionalized magnetic...
9011857 Methods of treating cancer by administering EMP2 antibodies  
The present invention provides methods and compositions useful in the treatment or prevention of Chlamydia infections and cancer. The methods and compositions inhibit the entry of Chlamydia into a...