Patents and Patent Applications from University of California System


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US20160327473 METHOD AND DEVICE FOR DETECTION AND SPATIAL MAPPING OF MERCURY CONCENTRATION IN WATER SAMPLES  
The concentration of mercury in a sample is measured by a reader secured to a camera-containing mobile electronic device. The reader has holders for sample and control solutions. First and second...
US20160326519 METHODS FOR DETECTING MODIFICATION RESISTANT NUCLEIC ACIDS  
Methods are provided for, inter alia, detecting nucleic acid molecules resistant to degradation, such as a plurality of RNA molecules bound to a ribosome, using various technologies including deep...
US20160326482 APPARATUS AND METHODS FOR MANIPULATION AND OPTIMIZATION OF BIOLOGICAL SYSTEMS  
A system includes a processor and a memory storing processor-executable instructions, which when executed by the processor direct the processor to provide control data indicating application of a...
US20160326419 THERMAL INTERFACE MATERIALS WITH ALLIGNED FILLERS  
Thermal interface materials and methods are disclosed. The thermal interface material can include a matrix and fillers. The filler can include magnetically functionalized graphene flakes that are...
US20160326149 HETEROATOM CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS  
Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions in a method of treating cancer. The dUTPase inhibitors disclosed...
US20160326126 AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME  
Provided herein is the design and synthesis of novel molecular rotor fluorophores useful for detection of amyloid or amyloid like proteins. The fluorophores are designed to exhibit enhanced...
US20160325013 BIOMIMETIC SCAFFOLDS  
The invention provides a composition comprising a nanofiber polymer in which the fibers of the nanofiber polymer arc aligned, and a molecule is covalcntly attached, either directly or through a...
US20160324966 POLYMERIC NANOCARRIERS WITH LIGHT-TRIGGERED RELEASE MECHANISM  
Near infrared radiation at a wavelength that induces resonance in water is used to remotely activate thermal plasticization of polymeric particles to trigger the release of encapsulated molecules...
US20160324434 SYSTEM AND METHOD OF IDENTIFYING SOURCES FOR BIOLOGICAL RHYTHMS  
In a system and method of determining regularity associated with a rhythm disorder of a heart, a derivative of a first cardiac signal at a plurality of first time points is processed against a...
US20160324234 ANATOMY SHADING FOR GARMENTS  
Systems and methods for anatomy shading and the garments that result therefrom are provided herein. More specifically, anatomy shading is any deliberate manipulation or addition of shading (a...
US20160324193 FASTING MIMICKING AND ENHANCING DIET FOR TREATING HYPERTENSION AND LIPID DISORDERS  
Methods for lowering hypertension, elevated total cholesterol, elevated glucose and insulin, elevated IGF-1, elevated triglyceride levels, and/or elevated CRP levels, and elevated liver fat...
9491028 Phase synchronization of modulation or demodulation for QAM-based multiband TSV-link  
A chip-to-chip communications circuit which is particularly well-suited for short range wired RF communication from one integrated circuit (chip) to another is presented. The circuits preferably...
9490866 Passive leakage cancellation networks for duplexers and coexisting wireless communication systems  
A passive cancellation network may include a transmit input having a configuration that passively receives a transmit signal from a transmitter that is to be wirelessly transmitted; a transmit...
9490454 Method for producing a high efficiency organic light emitting device having a transparent composite electrode comprising a film of conductive nanowires, carbon nanoparticles, light scattering nanoparticles, and a polymer support  
A method for producing high efficiency organic light emitting devices, that have an organic semiconductor active layer sandwiched between electrodes where at least one of the electrodes is a film...
9488908 Rapid fabrication of hierarchically structured supramolecular nanocomposite thin films in one minute  
Functional nanocomposites containing nanoparticles of different chemical compositions may exhibit new properties to meet demands for advanced technology. It is imperative to simultaneously achieve...
9488655 Biomarkers for detection of early- and late-stage endometrial cancer  
Biomarker proteins that can be used in the diagnosis of early-stage endometrial cancer are described. Methods of screening for endometrial cancer, as well as methods of detecting and monitoring...
9488599 Authentication device for full intact wine bottles  
Methods, devices and systems for identifying or authenticating an intact bottle of wine are provided.
9487745 Micro-patterned plate composed of an array of releasable elements surrounded with solid or gel walls  
A micro-patterned plate composed of an array of releasable elements surrounded by a gel or solid wall and methods of manufacture of the micropatterned plate. The surface properties of walls can be...
9487575 Compositions and methods for treatment of gynecologic cancers  
Molecules and compositions that can be used in the treatment of gynecologic cancers are described. ApoA-1, in particular, is demonstrated to inhibit the proliferation of cancer cells reduce tumor...
9487551 Small molecule compounds that control mammal-pathogenic nematodes  
The present invention relates to methods of modifying nematode behavior using certain isolated modulator compounds. Also disclosed are methods of promoting or inhibiting reproduction in a nematode...
9487534 Modulators of virus assembly as antiviral agents  
In addition to containing and protecting the viral genome, the capsid (protein shell) of hepatitis B virus (HBV) plays critical roles in the viral life cycle including regulation of intracellular...
9487522 SSH-2 (slingshot-2) inhibitors and methods for making and using them  
In alternative embodiments, the invention provides compositions that inhibit the polypeptide SSH-2, or SlingSHot-2, a phosphatase enzyme that regulates actin filaments, and methods for making and...
9486539 Nipah virus envelope pseudotyped lentiviruses and methods of their use  
The present invention relates to lentiviral particles which have been pseudotyped with Nipah virus (NiV) fusion (F) and attachment (G) glycoproteins (NiVpp-F/G). Additionally, the present...
9486474 Interstitial therapy for immediate symptom relief and chronic therapy in interstitial cystitis  
The present invention relates to a disorder of the lower urinary tract, and in particular, reducing the symptoms (including treatment) of interstitial cystitis in vivo. In a preferred embodiment,...
9486461 Methods and compositions for inducing apoptosis by stimulating ER stress  
The present invention provides a method for inducing apoptosis in selected cells by aggravating ER-stress. The aggravation of ER-stress is achieved in a specific manner by inhibiting SERCA...
9486457 Use of cinnabarinic acid as a modulator of immune responses in autoimmune disorders  
The present invention provides compounds and methods for preventing and treating an immune disorder in a subject.
9485994 Synergy-based biocontrol of plant pathogens  
Methods and compositions are provided for control of pathogenic fungal or oomycetous infection.
US20160323000 WIRELESS WEARABLE BIG DATA BRAIN MACHINE INTERFACE  
A wireless wearable high data throughput (big data) brain machine interface apparatus is presented. An implanted recording and transmitting module collects neural data from a plurality of...
US20160322782 MONOLITHIC INTEGRATION OF OPTICALLY PUMPED III-NITRIDE DEVICES  
The monolithic integration of optically-pumped and electrically-injected III-nitride light-emitting devices. This structure does not involve the growth of p-type layers after an active region for...
US20160322653 System and Method for Returning Material from the BR2 Side of an H2/BR2 Flow Battery Back after Crossover  
A flow battery system includes a first tank having a hydrogen reactant, a second tank having a bromine electrolyte, at least one cell including a hydrogen reactant side operably connected to the...
US20160322560 3D PIEZOELECTRIC POLYMER MATERIALS AND DEVICES  
Methods, systems, and devices are disclosed for fabricating 3D piezoelectric materials. In one aspect, a method includes photopolymerizing a selected portion of a two dimensional plane in a sample...
US20160321563 OPTIMIZED ARTIFICIAL INTELLIGENCE MACHINES THAT ALLOCATE PATROL AGENTS TO MINIMIZE OPPORTUNISTIC CRIME BASED ON LEARNED MODEL  
An optimized artificial intelligence machine may: receive information indicative of the times, locations, and types of crimes that were committed over a period of time in a geographic area;...
US20160321523 USING MACHINE LEARNING TO FILTER MONTE CARLO NOISE FROM IMAGES  
A method of producing noise-free images is disclosed. The method includes using machine learning incorporating a filter to output filter parameters using the training images. The machine learning...
US20160320771 Systems and Methods for Compensating for 3D Shape Deviations in Additive Manufacturing  
Methods and systems for predicting deformation error and compensating for shape deviation in Additive Manufacturing (AM) techniques include, in one aspect, a method including: obtaining a...
US20160319262 CAS9 CRYSTALS AND METHODS OF USE THEREOF  
The present disclosure provides atomic structures of Cas9 with and without polynucleotides bound thereto. Also provided is a computer-readable medium comprising atomic coordinates for Cas9...
US20160319238 DNA-CELL CONJUGATES  
The present invention provides conjugates of DNA and cells by linking the DNA to a native functional group on the cell surface. The cells can be without cell walls or can have cell walls. The...
US20160319041 INTRINSICALLY DISORDERED PROTEIN BRUSHES  
The disclosure relates to molecular protein brushes and devices comprising regions of protein brushes.
US20160318918 SMALL MOLECULE MODIFIERS OF THE HEC1-NEK2 INTERACTION IN G2/M  
Certain embodiments of the present invention provide selected compounds having a molecular structure according to Formula 1: In Formula 1, Z is —CO—, —SO—, or —SO2—; Ar is phenyl, heteroaryl, or...
US20160318207 METHOD FOR THE FABRICATION AND TRANSFER OF GRAPHENE  
Provided herein are processes for transferring high quality large-area graphene layers (e.g., single-layer graphene) to a flexible substrate based on preferential adhesion of certain thin metallic...
US20160317997 METHOD AND DEVICE TO SYNTHESIZE BORON NITRIDE NANOTUBES AND RELATED NANOPARTICLES  
Methods and apparatus for producing chemical nanostructures having multiple elements, such as boron and nitride, e.g. boron nitride nanotubes, are disclosed. The method comprises creating a plasma...
US20160317839 EXTERNAL BEAM RADIOTHERAPY AND IMAGING WITH RADIOACTIVE ISOTOPE  
A method of delivering external radiation beams to a target volume in a body portion includes positioning a radioactive isotope source at a plurality of locations spaced apart around the body...
US20160317814 EXTRACRANIAL IMPLANTABLE DEVICES, SYSTEMS AND METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS  
The present disclosure relates to methods, devices and systems used for the treatment of neurological disorders via stimulation of the superficial elements of the trigeminal nerve (“TNS”). More...
US20160317610 COMPOSITIONS AND METHODS FOR TREATING OVARIAN CANCER INCLUDING PREVENTING THE RECURRENCE THEREOF  
A method of treating ovarian cancer (OC) includes administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising vicrostatin and/or a protein...
US20160317468 USES OF CANNABIDIOL FOR TREATMENT OF INFANTILE SPASMS  
In some aspects, the invention relates to a method of treating or preventing infantile spasms in a subject, comprising administering to the subject a composition comprising cannabidiol (“CBD”). In...
US20160317226 SYSTEM AND METHOD OF COMBINED TISSUE IMAGING AND IMAGE-GUIDED LASER THERAPY  
A system and method for combined tissue imaging and image-guided laser therapy is provided. The apparatus has one or more imaging modalities and lasers that are controlled by a controller. The...
US20160317082 Xerostomia Markers  
Certain embodiments of the present invention provide methods of determining an efficacy of a xerostomia treatment in a mammalian subject (e.g., a human) that include the steps of comparing a first...
US20160317026 OPTICAL COHERENCE TOMOGRAPHY SYSTEM FOR HEALTH CHARACTERIZATION OF AN EYE  
This disclosure relates to the field of Optical Coherence Tomography (OCT). This disclosure particularly relates to methods and systems for providing larger field of view OCT images. This...
9484981 CDMA-based crosstalk cancellation for on-chip global high-speed links  
Synchronous CDMA/spread spectrum methods, devices, and systems are used to suppress crosstalk in clock-forwarded on-chip interconnects. Transmitting a spread spectrum signal across on-chip...
9484772 Wireless power mechanisms for lab-on-a-chip devices  
Methods, devices and systems are provided for wirelessly powering and controlling a lab-on-a-chip device. Direct current (DC) and alternating current (AC) signals can be produced at the...
9484176 Advanced penning ion source  
This disclosure provides systems, methods, and apparatus for ion generation. In one aspect, an apparatus includes an anode, a first cathode, a second cathode, and a plurality of cusp magnets. The...