Patents and Patent Applications from University of California System


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US20170059845 PARTIALLY COHERENT PHASE RECOVERY  
A system and method for incorporating partially coherent illumination models into the problem of phase and amplitude retrieval from a stack of intensity images. The recovery of phase could be...
US20170059666 OFFSET SUPPRESSION IN MICROMACHINED LORENTZ FORCE MAGNETIC SENSOR BY CURRENT CHOPPING  
Offsets (short and long term) are significantly reduced in a Lorentz force magnetometer circuit. A modulated bias current supplied to the magnetometer is chopped by periodically switching its...
US20170059595 HIGH THROUGHPUT BIOCHEMICAL FLUOROMETRIC METHOD FOR MEASURING HDL REDOX ACTIVITY  
In various embodiments, a new, robust fluorometric cell-free biochemical assay that measures HDL redox activity (HRA) is provided. In certain embodiments the assay is based on the oxidation of the...
US20170059557 MECHANICAL STRESS RESPONSE ANALYSIS OF CELLS AND TISSUES  
A method and device are disclosed for inducing mechanical stress in a cellular sample to evaluate mechanotransduction in the cellular sample. In one embodiment, the mechanical stress is induced by...
US20170059434 Capacitive Pressure Sensing using Ionic Film Sensors  
Thin-film pressure sensors are disclosed herein. Such sensors include one or more electrodes in contact with a sensing material. As the sensor deforms the capacitance of the sensor varies and is...
US20170058410 DEVICES AND METHODS FOR FORMING DOUBLE EMULSION DROPLET COMPOSITIONS AND POLYMER PARTICLES  
The present invention generally relates to double emulsion droplet compositions, polymer particles that can be formed from such double emulsion droplet compositions, and to methods and apparatuses...
US20170058328 FAST DIAGNOSIS AND PERSONALIZED TREATMENTS FOR ACNE  
Methods of diagnosing and treating patients afflicted with acne, including diagnosing one as having acne if the individual possesses RT4, RT5, RT7, RT8, RT9, or RT10. Methods for treating acne...
US20170058007 SELF-ASSEMBLED BETA SOLENOID PROTEIN SCAFFOLDS  
The present invention provides amyloid fibrils comprising a plurality of modified β solenoid protein (mBSP) monomers. The mBSP monomers are modified to enhance self-assembly and are useful in a...
US20170057908 ORGANIC SYNTHESIS APPLICATIONS OF NON-AQUEOUS FLUORIDE SALT SOLUTIONS  
Processes and reaction mixtures including non-aqueous solvent mixtures are presented. Non-aqueous solvent mixtures including fluoride salt and non-aqueous solvent combinations are provided that...
US20170056660 EXTRACRANIAL IMPLANTABLE DEVICES, SYSTEMS AND METHODS FOR THE TREATMENT OF NEUROPSYCHIATRIC DISORDERS  
The present disclosure relates to methods, devices, and systems used for the treatment of mood, anxiety, cognitive, and behavioral disorders (collectively, neuropsychiatric disorders) via...
US20170056376 SELECTIVE ACTIVATORS OF THE INTERMEDIATE CONDUCTANCE CA2+ACTIVATED K+ CHANNEL KCa3.1 AND THEIR METHODS OF USE  
Benzoxazole and indole type KCa3.1 activators as well as the therapeutic uses of such compounds in human or animal subjects and their use in ex vivo preservation of organs or tissues.
US20170055512 Microfabricated Surfaces for The Physical Capture of Insects  
Novel devices and methods of capturing, controlling and preventing infestation of insects using microfabricated surfaces are provided. In particular, a mechanism of insect capture inspired by the...
US20170055511 SYSTEMS AND METHODS FOR CLASSIFYING FLYING INSECTS  
Systems, apparatuses, and methods of classifying flying insects. The methods utilize recording the wingbeat frequency and amplitude spectrum of flying insects and comparing them to known or...
9583720 Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir  
The invention provides emissive materials and organic light emitting devices using the emissive materials in an emissive layer disposed between and electrically connected to an anode and a...
9582880 Automated image system for scoring changes in quantitative interstitial lung disease  
Automated image analysis systems and methods are disclosed to quantify change in fibrosis and interstitial lung disease. The system generates scoring changes in Quantitative Interstitial Lung...
9581586 Approach to asthma inhaler compliance using breath measurement of tetrafluoroethane  
The invention relates to measuring the effectiveness and an compliance of inhaler medication, such as for asthma treatment. In one embodiment, the invention provides a method of determining the...
9581214 Semi-active isolators based on magnetorheological nanocomposites  
Systems, devices, uses and methods relating to magnetorhological materials including carbon nanotubes, such as single-walled and multi-walled carbon nanotubes, are disclosed. Uses of...
9580726 Tomato plants comprising transgenic event Bs2-X5  
The invention provides seed and plants of tomato comprising transgenic event Bs2-X5 and progeny thereof comprising this transgenic event and uses of such seeds and plants in the production of...
9580678 Microfluidic tumor tissue dissociation device  
A tissue dissociation device includes an inlet coupled to a first stage having a single channel having an upstream end and a downstream end; a plurality of serially arranged intermediate stages,...
9580427 Kinase inhibitors  
Provided herein are compounds such as the compounds having the structure of Formula (XI) and methods of using the same, such as methods of inhibiting kinases.
9579400 Nanocarriers for drug delivery  
The present invention provides a nanocarrier having an interior and an exterior, the nanocarrier comprising at least one conjugate, wherein each conjugate includes a polyethylene glycol (PEG)...
9579346 Treatment of macrophage-related disorders  
The present invention provides a method of treating a macrophage related disease comprising administering to a subject in need thereof an effective amount of an oxidative agent or an...
US20170054096 HIGH MOBILITY POLYMER ORGANIC FIELD-EFFECT TRANSISTORS BY BLADE-COATING SEMICONDUCTOR:INSULATOR BLEND SOLUTIONS  
Conjugated polymer-based organic field-effect transistors have garnered attention since the solution processability of the semiconductor material raises the possibility of lower device fabrication...
US20170053417 AUTOMATED COMPARISON OF 3D IMAGES  
A method and apparatus for automated comparison of 3D images, such as specific shapes in images, for example, for detecting vascular changes and aneurysm growth. The method comprises an adaptive...
US20170053074 AUTOMATED QUALITY CONTROL OF DIAGNOSTIC RADIOLOGY  
A system is disclosed using a data-driven approach to objectively measure the diagnostic accuracy and value of diagnostic imaging reports using data captured routinely as part of the electronic...
US20170053059 METHODS FOR IDENTIFYING DRUG TARGETS BASED ON GENOMIC SEQUENCE DATA  
This invention provides a computational approach to identifying potential antibacterial drug targets based on a genome sequence and its annotation. Starting from a fully sequenced genome, open...
US20170052162 DEVICES AND METHODS FOR DETECTING HALOGENATED ORGANIC COMPOUNDS  
Disclosed herein are devices comprising a solid state gas sensor comprising a catalyst and a detection component capable of sensing halogenated gases through an increase or decrease in electrical...
US20170052107 METHOD AND DEVICE FOR HIGH-THROUGHPUT SOLUTION EXCHANGE FOR CELL AND PARTICLE SUSPENSIONS  
A method of exchanging fluids with suspended particles includes providing a microfluidic device with a first inlet channel operatively coupled to a source of particles and a second inlet channel...
US20170052104 Determining Fluid Reservoir Connectivity Using Nanowire Probes  
Systems and methods of fabricating and functionality patterned nanowire probes that are stable under fluid reservoir conditions and have imageable contrast are provided. Optical imaging and...
US20170051365 MULTIVOLUME DEVICES, KITS AND RELATED METHODS FOR QUANTIFICATION AND DETECTION OF NUCLEIC ACIDS AND OTHER ANALYTES  
Provided are devices comprising multivolume analysis regions, the devices being capable of supporting amplification, detection, and other processes. Also provided are related methods of detecting...
US20170051317 Modified Host Cells Having Tolerance to Alpha-Olefins  
The present invention provides methods for improving microbial tolerance to alpha olefin compounds, host cells having increased tolerance to such compounds, and method of using the host cells to...
US20170051312 METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION  
The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a...
US20170051310 METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION  
The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a...
US20170050888 Production of Ceramic Metal Oxide Membranes by Means of Reactive Electrospinning  
Traditionally, the manufacturing of ceramic metal oxide membranes is often expensive and extremely labor intensive due to the often necessary post-processing steps. The present invention discloses...
US20170050153 Polyaniline-Based Chlorine Resistant Hydrophilic Filtration Membranes  
In one aspect, the invention relates to chlorine-resistant filtration membranes comprising n-alkyl substituted polyaniline derivatives for use in, for example, water purification, and methods for...
US20170049901 BIS-POLYMER LIPID-PEPTIDE CONJUGATES AND NANOPARTICLES THEREOF  
The present invention provides bis-polymer lipid-peptide conjugates containing a hydrophobic block and headgroup containing a helical peptide and two polymer blocks. The conjugates can...
US20170049853 MITOCHONDRIAL-DERIVED PEPTIDE MOTS3 REGULATES METABOLISM AND CELL SURVIVAL  
MOTS3 is a novel polypeptide. Methods of treating diseases such as diabetes, obesity, fatty liver, and cancer using MOTS3 and pharmaceutical compositions thereof are disclosed herein.
US20170049785 ESTROGEN COMBINATION FOR TREATMENT OF MULTIPLE SCLEROSIS  
Provided are methods for treating multiple sclerosis using a continuous regimen of estrogen in combination with periodic administration of a progestogen.
US20170049402 SYSTEM AND METHOD FOR RECONSTRUCTING CARDIAC ACTIVATION INFORMATION  
In a system and method for reconstructing cardiac activation information, an analysis cardiac signal and a reference cardiac signal are accessed and processed to determine a first point of change...
9578440 Method for controlling a speaker array to provide spatialized, localized, and binaural virtual surround sound  
A signal processing method and system are provided for delivering spatialized sound using highly optimized inverse filters to deliver narrow localized beams of sound from the included speaker...
9577847 Non-reciprocal components with balanced distributedly modulated capacitors (DMC)  
A non-reciprocal radio frequency transceiver front end utilizing multiple time-varying transmission lines (TVTLs) implemented using distributed modulated capacitors (DMC) to exploit time-varying...
9577298 High efficiency iron electrode and additives for use in rechargeable iron-based batteries  
An iron electrode and a method of manufacturing an iron electrode for use in an iron-based rechargeable battery are disclosed. In one embodiment, the iron electrode includes carbonyl iron powder...
9576799 Doping of a substrate via a dopant containing polymer film  
Disclosed herein is a method for doping a substrate, comprising disposing a coating of a composition comprising a copolymer, a dopant precursor and a solvent on a substrate; where the copolymer is...
9576108 Method for determining an infusion parameter  
A method for planning an infusion of a medical substance into a target region acquires non-patient-specific anatomical data from an atlas in the form of target region geometry information...
9575042 Ligand-modified metal clusters for gas separation and purification  
Provided is an organic ligand-bound metal surface that selects one gaseous species over another. The species can be closely sized molecular species having less than 1 Angstrom difference in...
9574919 Reducing false alarms with multi-modal sensing for pipeline blockage  
A detection system includes a first sensor coupled to a pipe associated with a pump and generates temperature data associated with a temperature of the pipe. The system includes a second sensor...
9574728 Laser-driven white lighting system for high-brightness applications  
A high-power, high-brightness lighting system for large venue lighting, which includes a laser diode as the excitation source and one or more phosphor materials placed at a remote distance from...
9574244 Molecular method for universal detection of citrus viroids  
The present invention provides methods for universally detecting citrus viroids in plant material such as germplasm. In particular embodiments, the invention enables the determination of citrus...
9573977 Method for preventing neoplastic transformation by inhibition of retinoblastoma protein inactivation  
A method for preventing neoplastic transformation by inhibition of cell cycle progression into S phase by preventing the inactivation of Retinoblastoma protein (Rb).
9573880 Benzo lipoxin analogues  
Benzolipoxin analogs, methods of their preparation and pharmaceutical compositions containing the compounds are provided. The compounds and compositions are useful in methods for treatment of...