Sign up

Patents and Patent Applications from University of California System


Match Document Document Title
US20150088064 UPPER ESOPHAGEAL SPHINCTER DILATOR  
An apparatus for dilating an upper esophageal sphincter. The apparatus includes an elongated expandable member having a cross-section shaped to support a natural shape of an upper esophageal...
US20150087628 COMPOSITIONS AND METHODS FOR TREATING CANCER  
K-Ras is the most frequently mutated oncogene in human cancer. Disclosed herein are compositions and methods for modulating K-Ras and treating cancer.
US20150087050 FUNCTIONALIZED POROUS SILICON NANOPARTICLES AND USE THEREOF IN PHOTODYNAMIC THERAPY  
Disclosed are nanovectors of formula (I) that can be used simultaneously for the targeting, imaging and treatment, by photodynamic therapy, of cancer cells, and to biodegradable silicon...
US20150087042 Genetically Modified Host Cells and Use of Same for Producing Isoprenoid Compounds  
The present invention provides genetically modified eukaryotic host cells that produce isoprenoid precursors or isoprenoid compounds. A subject genetically modified host cell comprises increased...
US20150086884 High Efficiency Nickel-Iron Battery  
A rechargeable battery includes an iron electrode comprising carbonyl iron composition dispersed over a fibrous electrically conductive substrate. The carbonyl iron composition includes carbonyl...
US20150086581 Fast Diagnosis and Personalized Treatment for Acne  
Methods of diagnosing and treating patients afflicted with acne, including diagnosing one as having acne if the individual possesses RT4, RT5, RT7, RT8, RT9, or RT10. Methods for treating acne...
US20150086570 BIOMARKERS FOR USE IN INTEGRIN THERAPY APPLICATIONS  
The present invention relates to biomarkers for use in determining the sensitivity of patients to therapy with αvβ6 integrin inhibition or therapy with TGF-β pathway inhibitors. The biomarker pr...
US20150086542 COMPOSITIONS AND METHODS FOR THE PREVENTION OF MICROBIAL INFECTIONS  
This disclosure provides methods and compositions to inhibit or prevent infection of a cell by a bacteria that exports DNABII proteins by administering to a tissue infected with the bacteria an...
US20150084219 METHOD AND KIT FOR FORMING PLASTIC LENSES FROM MOLDS FORMED ON SURFACE WITH VARIED WETTABILITY  
This disclosure provides a monolithic mold including a plurality of lens forming features that can be used to simultaneously form a plurality of lenses with different sizes and shapes. The mold can...
US20150083579 GEOMETRY ENHANCEMENT OF NANOSCALE ENERGY DEPOSITION BY X-RAYS  
A principle is established to show that nanoscale energy deposition in water by X-rays can be greatly enhanced via the geometry of nanostructures. The calculated results show that enhancement over...
8989232 Nanoscale coaxial lasers  
Methods, structures, devices and systems are disclosed for implementing compact (e.g., nanoscale) coaxial lasers with coaxial cavity geometries which can be used to construct various coaxial cavity...
8988923 Nonvolatile magneto-electric random access memory circuit with burst writing and back-to-back reads  
Voltage controlled magneto-electric tunnel junctions (MEJ) and associated memory devices are described which provide efficient high speed switching of non-volatile magnetic random access memory...
8988599 Illumination sphere with intelligent LED lighting units in scalable daisy chain with interchangeable filters  
A controllable lighting system may include a plurality of light source groups, a group controller for each light source group, a master controller, and a network communication system. Each group...
8988237 System and method for failure prediction for artificial lift systems  
A computer-implemented reservoir prediction system, method, and software are provided for failure prediction for artificial lift systems, such as sucker rod pump systems. The method includes a...
8988236 System and method for failure prediction for rod pump artificial lift systems  
A computer-implemented reservoir prediction system, method, and software are provided for failure prediction for artificial lift well systems, such as sucker rod pump systems. The method includes...
8987649 Methods for optical amplified imaging using a two-dimensional spectral brush  
An apparatus and method for ultrafast real-time optical imaging that can be used for imaging dynamic events such as microfluidics or laser surgery is provided. The apparatus and methods encode...
8987538 Carbon nanohoops and methods of making  
The present invention provides cycloparaphenylene compounds, their macrocyclic precursors, and methods for making the compounds. The cycloparaphenylene compounds can be used to prepare armchair...
8987332 Methods of treating inflammatory conditions  
The present invention provides methods of treating a β-arrestin2 mediated and/or GPR120 mediated response in a subject. The β-arrestin2 mediated and/or GPR120 mediated response can be i...
8987294 Small molecule inhibitors of the α4-paxillin interaction  
The present invention is directed to novel compounds that are able to inhibit the interaction of paxillin or its paralogues, including leupaxin or Hic-5, with alpha.4 integrin or its binding...
8987192 Potent and selective mediators of cholesterol efflux  
The present invention provides a family of non-naturally occurring polypeptides having cholesterol efflux activity that parallels that of full-length apolipoproteins (e.g., Apo AI and Apo E), and...
8986655 Compositions, devices, and methods related to prostate-specific membrane antigen  
PSMA ligands, compositions, and methods therefore are disclosed where the ligand is a peptide having the sequence X1X2CVEVX3QNSCX4X5 where X1-X5 are independently a natural or non-natural amino...
8986469 Amorphous alloy materials  
Design and fabrication processes and compositions for bulk metallic glass materials. Examples of bulk metallic glasses based on the described compositions may contain a high atomic percent of...
8985118 Retention device  
This application presents retention devices that afford the user quick and easy placement. These retention devices may accommodate objects of various shapes and sizes. The device provides sturdy...
US20150082494 Cell Modified in the Expression of a Nucleotide Sugar Transporter  
The present invention provides for a genetically modified eukaryotic host cell comprising (a) a gene encoding a first nucleotide sugar transporter (NST) operably linked to a promoter, wherein the...
US20150081012 MESH ENCLOSED TISSUE CONSTRUCTS  
A scaffold to form tissue membranes, comprising: at least one layer of mesh having a first side and a second side, the layer of mesh being either a woven wire metal mesh or a flat metal sheet that...
US20150080410 Cancer Specific Mitotic Network  
Developed here is a mitotic network comprising a signature of up to 54 genes, and including also sub-sets of genes within the signature, which can identify members by requiring higher correlation...
US20150080344 PHOSPHONATES WITH REDUCED TOXICITY FOR TREATMENT OF VIRAL INFECTIONS  
There are provided, inter alia, acyclic nucleoside phosphonate compounds having reduced toxicity and enhanced antiviral activity, and pharmaceutically accepted salts and solvates thereof. There are...
US20150080319 Inhibition Of Tace Activity With Cyclic Peptides  
A method is provided for inhibiting TACE activity in a human subject, through the administration of a θ-defensin, analog, or derivative. Such a θ-defensin, analog, or derivative can be e...
US20150080294 METHODS FOR PROMOTING LIPOLYSIS AND OXIDATION IN LIVER AND ADIPOSE TISSUE USING CATESTATIN  
The invention provides methods for treating obesity in a subject comprising administering an effective amount of catestatin (CST) or its equivalent to a subject afflicted with obesity so as to...
US20150079299 AEROSOL COATING PROCESS BASED ON VOLATILE, NON-FLAMMABLE SOLVENTS  
A method for coating target surfaces by spraying an atomized liquid formulation of a volatile solvent, a dispersant, and adhesion promoter, a polymer, a plasticizer and particulates of an active...
US20150079116 DIAGNOSTIC TOOLS FOR RESPONSE TO 6-THIOPURINE THERAPY  
NK cell licensing predisposes patients to chronic inflammatory disease. Methods and kits to diagnose and treat chronic inflammatory disease based on genetic haplotype and cytokine profile are...
US20150079089 EMP2 REGULATES ANGIOGENESIS IN CANCER CELLS THROUGH INDUCTION OF VEGF  
Disclosed herein are methods and compositions for modulating neovascularization. The disclosed compositions find particular use in the treatment of uterine cancers, specifically endometrial cancers.
US20150079071 NON-CATALYTIC DOMAIN TARGETS IN MATRIX METALLOPROTEASE PROTEINS FOR CANCER THERAPIES  
The present invention provides compositions and methods for inhibiting MMPs, especially MMP-3, MMP-9 and MMP-14. The invention relates to the field of diagnostic and prognostic methods of human...
US20150079047 OCULAR THERAPEUTICS USING EMBRYONIC STEM CELL MICROVESICLES  
Disclosed is a therapeutic composition comprising human embryonic stem cell-derived micro vesicles, and methods of their use, including treatment of eye pathologies and of obtaining retinal neural...
US20150079039 SINUSITIS DIAGNOSTICS AND TREATMENTS  
Provided herein are compositions for improving sinus microbiota and treating sinusits. Further provided are methods of detecting imbalance in the sinus microbiota that can be indicative of...
US20150079005 POLYMERIC NANOCARRIERS WITH LINEAR DUAL RESPONSE MECHANISM  
Nanocarriers are synthesized with polymers that respond to lower pH and/or ROS by being degraded. The compositions may be utilized to selectively deliver payloads within patients by responding to...
US20150079003 Methods and Compositions for Cancer Diagnosis  
The present invention provides reagents and methods for detecting cancer precancerous lesions in a patient.
US20150076539 SINGLE-PHASE AND FULL-COLOR PHOSPHOR  
A composition of matter including a phosphor having an emission peak in each of a blue, green, and red color region of the Electromagnetic spectrum, wherein the phosphor is excitable by light...
US20150076533 INTERDIGITATED MULTIPLE PIXEL ARRAYS OF LIGHT-EMITTING DEVICES  
The present invention discloses a plurality of interdigitated pixels arranged in an array, having a very low series-resistance with improved current spreading and improved heat-sinking. Each pixel...
US20150076470 Luminescent Cyclometallated Iridium (III) Complexes Having Acetylide Ligands  
The present invention relates to phosphorescent (triplet-emitting) organometallic materials. The phosphorescent materials of the present invention comprise Ir(III)cyclometallated alkynyl complexes...
US20150076412 MANUFACTURED PRODUCT WITH OPTICALLY ENCODED PARTICLE TAG AND ID METHOD  
The invention concerns an article of manufacture that is a manufactured product marked with a microparticle and a method of marking manufactured produces. The microparticle tag includes a...
US20150076407 Novel Doped Halide Scintillators  
The present invention provides for a composition comprising an inorganic scintillator comprising a doped halide, useful for detecting nuclear material.
US20150075622 SYNTHESIS OF WATER SOLUBLE DOPED CONJUGATED POLYELECTROLYTES FOR APPLICATIONS IN ORGANIC ELECTRONICS  
A method of fabricating a composition of matter, including fabricating one or more conjugated polyelectrolytes each comprising a donor-acceptor copolymer backbone and one or more anionic side...
8984661 Probes for multidimensional nanospectroscopic imaging and methods of fabrication thereof  
This disclosure provides systems, methods, and apparatus related to probes for multidimensional nanospectroscopic imaging. In one aspect, a method includes providing a transparent tip comprising a...
8984297 Authenticated adversarial routing  
A routing protocol is used to transmit messages from a sender to a receiver over a network of nodes, where adversaries can control links between the nodes and can also control the behavior of a...
8981056 Variant LovD polypeptide  
The invention disclosed herein relates to methods and materials for producing simvastatin and related compounds such as huvastatin. In particular, the disclosure teaches that variants of the LovD...
8981046 Synthetic cell platforms and methods of use thereof  
The present invention provides synthetic cell platforms. The synthetic cell platforms can be used for culturing cells in vitro. The synthetic cell platforms can also be implanted together with...
8980961 Conversion of carbon dioxide to methanol using bi-reforming of methane or natural gas  
The invention provides for \ a method of forming methanol by combining a mixture of methane, water and carbon dioxide under reaction conditions sufficient to form a mixture of hydrogen and carbon...
8980899 Methods of inhibiting Ire1  
Disclosed herein are, inter alia, methods for inhibiting Ire1 activity.
8980859 Aegyptin and uses thereof  
The present invention relates to the discovery of the Aegyptin gene and Aegyptin protein, a molecule that interacts with collagen and inhibits platelet adhesion, activation and aggregation. Novel...