Patents and Patent Applications from University of California System


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9359623 Methods and compositions for the production of fatty acids in photosynthetic prokaryotic microorganisms  
Provided herein are methods and compositions for the production of renewable fatty acids from photosynthetic prokaryotic microorganisms, such as a blue green algae, any specie of the phylum...
9359591 Glucomannan scaffolding for three-dimensional tissue culture and engineering  
The present invention provides a neutralized glucomannan scaffold capable of promoting cell growth and suitable for three-dimensional tissue culture and engineering. The present invention also...
9359360 TLR agonists  
The present invention provides for TLR agonist conjugates (compounds) and compositions, as well as methods of using them. The compounds of the invention are broad-spectrum, long-lasting, and...
9359309 Synthesis of syrbactin proteasome inhibitors  
The disclosure relates generally to methods for the preparation of a family of natural compounds, the syrbactins and their analogs.
9358283 Diatom-based vaccines  
This invention provides diatom-based vaccines.
9358249 Use of Pateamine A for the treatment of age-related muscle wasting  
In certain embodiments this invention pertains to the discovery that inhibition of the expression and/or activity of eukaryotic initiation factor 4A (eIF4A) inhibits the aging process....
US20160157022 ELECTROSTATIC GRAPHENE SPEAKER  
This disclosure provides systems, methods, and apparatus associated with an electrostatically driven graphene speaker. In one aspect, a device includes a graphene membrane, a first frame on a...
US20160156327 NON-RECIPROCAL, TUNABLE NOTCH AMPLIFYING RF FRONT-ENDS BASED ON DISTRIBUTEDLY MODULATED CAPACITORS (DMC)  
A tunable notch filter/amplifier based on the non-reciprocal operation of distributedly modulated capacitors (DMC) formed for an RF front end. In one embodiment within the DMC is formed into a...
US20160156155 STRUCTURE AND METHOD FOR THE FABRICATION OF A GALLIUM NITRIDE VERTICAL CAVITY SURFACE EMITTING LASER  
A III-Nitride based Vertical Cavity Surface Emitting Laser (VCSEL), wherein a cavity length of the VCSEL is controlled by etching.
US20160156066 POLYMER ELECTROLYTES FOR ELECTROCHEMICAL CELLS  
Thin polymer layers for use as electrolytes in electrochemical cells, and associated electrochemical cells and methods, are generally described. The thin polymer layers may be formed by initiated...
US20160155974 COMPLEX PNICTIDE METAL HALIDES FOR OPTOELECTRONIC APPLICATIONS  
An optoelectronic device comprising an active layer sandwiched between a first electrode and a second electrode. The active layer comprises a material of the formula AaBbMmXx, wherein A represents...
US20160155595 MICROMECHANICAL RESONANT SWITCHES AND CHARGE PUMPS  
A circuit of N micromechanical resonant switches (resoswitches) is presented, which mimics a Dickson charge pump to amplify an input voltage to an output voltage of N plus 1 times the input...
US20160154905 TIMING VIOLATION RESILIENT ASYNCHRONOUS TEMPLATE  
An asynchronous circuit may include a single-rail logic datapath; one or more error-detecting latches; a controller that controls the error-detecting latches; and delay lines. The controller and...
US20160153977 NOVEL GOLD NANOPARTICLE AGGREGATES AND THEIR APPLICATIONS  
The invention is drawn to a method of using nanoparticle aggregates to form sensors and optical filters. Properly sized (60 and 200 nm) nanoparticle aggregates with cores having a sulfur-oxygen...
US20160153969 Neuronal Cells Cultured On Microparticles and Methods of Using Same  
The present invention provides methods for culturing neuronal cells for transplantation into a subject. The methods include culturing neuronal cells with microparticles to provide a microparticle...
US20160152907 METHODS TO PRODUCE FUELS  
The present disclosure generally relates to the catalytic conversion of alcohols into hydrocarbon ketones suitable for use as fuels. More specifically, the present disclosure relates to the...
US20160152719 COMPOSITIONS AND METHODS RELATED TO STRUCTURES THAT CROSS THE BLOOD BRAIN BARRIER  
Provided herein are compositions, kits, methods and systems related to administering a structure that crosses the blood brain barrier (BBB) along with a monosaccharide, either simultaneously or...
US20160152710 MILK FAT GLOBULE EPIDERMAL GROWTH FACTOR 8 REGULATES FATTY ACID UPTAKE  
Methods and compositions for regulating fatty acid uptake and/or decreasing gastric motility in an animal are provided. The method comprises administering an antagonist of integrin αvβ3 or αvβ5 to...
US20160152560 Compounds for the treatment of hypertension and hypertensive end stage renal disease  
This disclosure relates to compounds and compositions useful for the treatment of hypertension and hypertensive renal disease.
US20160151939 MAGNETICALLY CONTROLLED CASTING PROCESS FOR MULTISTRUCTURAL MATERIALS  
The disclosure provides a method to produce solid materials displaying structural ordering which can be controlled through a wide range of sizes and shapes. The process involves casting a medium,...
US20160151784 MICROFLUIDIC DEVICES WITH FLEXIBLE OPTICALLY TRANSPARENT ELECTRODES  
Microfluidic devices in which electrokinetic mechanisms move droplets of a liquid or particles in a liquid are described. The devices include at least one electrode that is optically transparent...
US20160151534 ANTI-MICROBIAL PEPTIDES AND METHODS OF USE THEREOF  
The present disclosure provides antimicrobial peptides, and compositions comprising same. The present disclosure further provides methods of inhibiting microbial growth.
US20160151470 T-CELL IMMUNOGENS DERIVED FROM ANTI-VIRAL PROTEINS AND METHODS OF USING SAME  
Isolated polypeptides related to endogenous anti-viral polypeptides; and compositions, including immunogenic compositions, comprising a subject isolated polypeptide are disclosed herein. A subject...
US20160151380 THERAPIES FOR DISEASES CAUSED BY ARTHROPOD-BORNE PARASITES  
The present disclosure provides methods for treating or preventing diseases caused by arthropod-borne parasites by administration of a protein kinase inhibitor to a mammalian subject infected with...
US20160151379 COMBINATION THERAPIES FOR MALARIA  
The present disclosure provides methods for treating or preventing malaria by administration of a protein kinase inhibitor and optionally one or both of a further protein kinase inhibitor and an...
US20160151350 PHARMACEUTICAL COMPOSITIONS WHICH INHIBIT FKBP52-MEDIATED REGULATION OF ANDROGEN RECEPTOR FUNCTION AND METHODS OF USING SAME  
Pharmaceutical compositions that bind to a predicted FK506 Binding Protein 52 (FKBP52) interaction surface on the androgen receptor hormone binding domain, otherwise known as FKBP52 Targeting...
US20160151310 ENTERICALLY COATED CYSTEAMINE, CYSTAMINE AND DERIVATIVES THEREOF  
The disclosure provides oral cysteamine and cystamine formulations useful for treating cystinosis and neurodegenerative diseases and disorders. The formulations provide controlled release...
9356779 Systems and methods for identity-based encryption and related cryptographic techniques  
A method and system for encrypting a first piece of information M to be sent by a sender [100] to a receiver [110] allows both sender and receiver to compute a secret message key using...
9356582 Low jitter tunable voltage control oscillator with self calibration circuits to reduce chip fabrication process variation  
A voltage controlled oscillator (VCO) which can be configured with a smaller tuning range than is ordinarily required is presented. Ordinarily, the tuning range is selected much broader than the...
9356431 High power blue-violet III-nitride semipolar laser diodes  
A high power blue-violet Ill-nitride semipolar laser diode (LD) with an output power in excess of 1 W, a slope efficiency of more than 1 W/A, and an external quantum efficiency (EQE) in excess of...
9356245 Carbene metal complexes as OLED materials  
An organic light emitting device having an anode, a cathode and an organic layer disposed between the anode and the cathode is provided. In one aspect, the organic layer comprises a compound...
9356241 End-group-directed self-assembly of organic compounds useful for photovoltaic applications  
The present invention provides for an organic compound comprising electron deficient unit covalently linked to two or more electron rich units. The present invention also provides for a device...
9356224 Thin film bismuth iron oxides useful for piezoelectric devices  
The present invention provides for a composition comprising a thin film of BiFeO3 having a thickness ranging from 20 nm to 300 nm, a first electrode in contact with the BiFeO3 thin film, and a...
9355764 Magnetoelectric control of superparamagnetism  
A magnetoelectric composite device having a free (i.e. switchable) layer of ferromagnetic nanocrystals mechanically coupled a ferroelectric single crystal substrate is presented, wherein...
9355699 Voltage-controlled magnetic anisotropy (VCMA) switch and magneto-electric memory (MERAM)  
Voltage controlled magnetic tunnel junctions and memory devices are described which provide efficient high speed switching of non-volatile magnetic devices at high cell densities. Implementations...
9354233 A+ biomarker assays  
Disclosed herein assay methods which comprise detecting the presence, absence or amount of at least one antibody which specifically binds a first biomarker or an epitope thereof and at least one...
9353455 Dielectrophoresis and electrodeposition process for selective particle entrapment  
A method of creating a structure on an electrode includes exposing an electrode to a solution containing a polymerizable monomer and particles and applying an AC voltage to the electrode so as to...
9353352 Embryonic stem cell specific microRNAs promote induced pluripotency  
The methods of the present application describe that introduction of physiologically relevant miRNAs can enhance or modulate somatic cell reprogramming, generating induced pluripotent stem cells...
9353116 Methods and compositions for kinase inhibition  
The present invention sets forth a new chemical genetic approach for engineering kinase enzymes with a cysteine gatekeeper residue as well as for developing electrophilic inhibitors thereto. The...
9353075 Disubstituted beta-lactones as inhibitors of N-acylethanolamine acid amidase (NAAA)  
The present invention provides compounds and pharmaceutical compositions for inhibiting N-acylethanolamine acid amidase (NAAA). Inhibition of NAAA is contemplated as a method to sustain the levels...
9352963 Nanomotor-based patterning of surface microstructures  
Among other things, methods, systems and apparatus are described for implementing nanomotor-based micro- and nanofabrication. In one aspect, a method of fabricating nanoobjects comprises...
9352155 Chaotic desynchronization of neural populations with non-pulsatile inputs  
A method is provided for finding an energy-optimal stimulus which gives a positive Lyapunov exponent, and hence desynchronization, for a neural population. The method is illustrated for three...
9351855 Powered lower extremity orthotic and method of operation  
A powered lower extremity orthotic, including a shank link coupled to an artificial foot, a knee mechanism connected to the shank link and a thigh link, is controlled by based on signals from...
9351490 Selectively targeted antimicrobial peptides and the use thereof  
The present invention relates to targeting peptides capable of specifically binding to microbial organisms (e.g., P. aeruginosa or S. mutans), antimicrobial peptides having antimicrobial...
US20160149746 PHASE SYNCHRONIZATION OF MODULATION OR DEMODULATION FOR QAM-BASED MULTIBAND TSV-LINK  
A chip-to-chip communications circuit which is particularly well-suited for short range wired RF communication from one integrated circuit (chip) to another is presented. The circuits preferably...
US20160149111 MAGNETIC FLUX-TO-VOLTAGE TRANSDUCER BASED ON JOSEPHSON JUNCTION ARRAYS  
A device and method for converting magnetic flux to voltage uses a Fraunhofer pattern of a 1D array of long Josephson junctions. The 1D array of Josephson junctions may include from 1 to 109...
US20160148840 THROUGH SILICON VIAS AND THERMOCOMPRESSION BONDING USING INKJET-PRINTED NANOPARTICLES  
Apparatus and method for filling and optionally bumping through-silicon vias (TSVs) in device circuits utilizing inkjet printheads for ejecting sufficiently small droplets of conductive...
US20160148759 POROUS INTERCONNECTED CORRUGATED CARBON-BASED NETWORK (ICCN) COMPOSITE  
A porous interconnected corrugated carbon-based network (ICCN) composite and methods for making the same are disclosed. The porous ICCN composite is made up of a plurality of carbon layers that...
US20160148103 FAST BEHAVIOR AND ABNORMALITY DETECTION  
A system includes an interface configured to receive time series data representing information from a plurality of sensors, and a processor configured to construct a behavior model based on the...
US20160146895 Accurate Assessment of the State of Charge of Electrochemical Cells  
Provided are methods, systems and devices for thermodynamically evaluating electrochemical systems and components thereof, including electrochemical cells such as batteries. The present systems...