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Patents and Patent Applications from University of California System


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US20140320601 APPARATUS AND METHOD FOR AN INCLINED SINGLE PLANE IMAGING MICROSCOPE BOX (ISPIM BOX)  
An apparatus for inclined single plane Illumination microscopy of a sample includes a laser for launching excitation light beams at a plurality of wavelengths, a laser beam expander, an injection...
US20140320212 RADIO FREQUENCY POWER AMPLIFIERS  
A radio frequency power amplifier amplifies an input signal at an input port, and produces an output signal at an output port. The power amplifier may include one or more amplifier stages. An...
US20140318964 Two-Chamber Dual-Pore Device  
Provided is a device comprising a channel through and defined by a plurality of layers surrounding the channel, the channel connecting a first and a second chambers separated by the plurality of...
US20140318627 HIGHLY EFFICIENT POLYMER SOLAR CELL BY POLYMER SELF-ORGANIZATION  
A method of manufacturing a polymer composite film for an active layer of a photovoltaic cell according to an embodiment of this invention includes providing a quantity of a solution of a polymer...
US20140318592 ENHANCEMENT OF THERMOELECTRIC PROPERTIES THROUGH POLARIZATION ENGINEERING  
A method for enhancement of thermoelectric properties through polarization engineering. Internal electric fields created within a material are used to spatially confine electrons for the purpose of...
8874439 Systems and methods for blind source signal separation  
Signal separation techniques based on frequency dependency are described. In one implementation, a blind signal separation process is provided that avoids the permutation problem of previous signal...
8873837 Image-based crack detection  
Contact-less remote-sensing crack detection and/quantification methodologies are described, which are based on three-dimensional (3D) scene reconstruction, image processing, and pattern...
8873132 Method and apparatus for generation and detection of rogue waves  
Methods and systems are provided for generation and detection of rogue waves, including hydrodynamic rogue waves and optical rogue waves. A method for generating an optical rogue wave comprises the...
8872799 Scalable distributed/cooperative/collaborative paradigm for multi-user interaction with projection-based display walls  
A method of distributed/cooperative/collaborative gesture management may comprise queuing actions of gestures as the gestures move across a display, processing the actions of each of the gestures...
8871734 Transgene delivering retrovirus targeting collagen exposed at site of tissue injury  
A viral or non-viral vector particle having a modified viral surface protein wherein the viral surface protein is modified to include a targeting polypeptide including a binding region which binds...
8871507 Method of inhibiting apolipoprotein-E expression comprising administering a triarylmethyl amine compound  
This invention offers an effective method of inhibiting the expression of apolipoprotein E by mammalian cells. Apolipoprotein E is a protein that plays a significant role in the development of...
8871447 Immunogens and corresponding antibodies specific for high molecular weight aggregation intermediates common to amyloids formed from proteins of differing sequence  
Compositions of matter that comprise one or more conformational epitopes found on amyloid peptide aggregates, antibodies to such epitopes and methods for making and using the compositions,...
8870060 Apparatus and method for dispersive fourier-transform imaging  
A barcode reading apparatus and method in which the spectrum of a probe light is first Fourier-transformed into space, directed upon a barcode, and then Fourier-transformed converting the...
US20140316719 STRESS DETECTION IN RAIL  
Methods and apparatus, including computer program products, are provided for determining rail stress. The method may include generating at least one ultrasonic guided wave to enable the at least...
US20140316503 PARYLENE-BASED MICROELECTRODE ARRAY IMPLANT FOR SPINAL CORD STIMULATION  
An implantable electrode array assembly configured to apply electrical stimulation to the spinal cord. A substantially electrically nonconductive layer of the device has a first portion...
US20140316392 Method, Apparatus, and a System for a Water Jet  
A fluid or laser jet instrument may be used for manually performing eye surgery or any emulsification technique.
US20140316275 HIGH FREQUENCY ULTRASONIC CONVEX ARRAY TRANSDUCERS AND TISSUE IMAGING  
A high frequency ultrasonic transducer may include a plurality of adjacent ultrasonic transducer elements. The adjacent transducer elements may be sized and configured so as to resonate at a...
US20140315861 BETA-LACTAMASE INHIBITORS  
Disclosed herein inter alia are Boron containing compounds and methods for treating infections related to antibiotic resistant microorganisms.
US20140315829 Compositions And Methods For Enhancing Sialic Acid Levels In Tissue  
The invention relates to compositions and methods for increasing sialic acid uptake and/or incorporation into tissue following gastrointestinal ingestion of compositions that contain sialic acid.
US20140315805 LOCALLY RELEASED GROWTH FACTORS TO MEDIATE MOTOR RECOVERY AFTER STROKE  
Methods of improving recovery of a mammal after an ischemic event (e.g., stroke) are provided. In various embodiments the methods involve administering a neural growth factor (e.g., BDNF) into the...
US20140315723 Tunnel Junction Fabrication  
A method for fabricating a tunnel junction includes depositing a first electrode on a substrate, depositing a wetting layer having a thickness of less than 2 nm on the first electrode, using atomic...
US20140315308 GLUCOMANNAN SCAFFOLDING FOR THREE-DIMENSIONAL TISSUE CULTURE AND ENGINEERING  
The present invention provides a neutralized glucomannan scaffold capable of promoting cell growth and suitable for three-dimensional tissue culture and engineering. The present invention also...
US20140315287 SYSTEM AND METHOD FOR DEFORMING AND ANALYZING PARTICLES  
A system for deforming and analyzing a plurality of particles carried in a sample volume includes a substrate defining an inlet, configured to receive the sample volume, and an outlet; and a...
US20140315195 METHOD FOR EXOSOMAL BIOMARKER DETECTION BY ELECTRIC FIELD-INDUCED RELEASE AND MEASUREMENT  
The molecules harbored in exosomes play important roles in biological science. A highly desirable goal for exosome research is the rapid, simple, simultaneous tracking and quantification of exosome...
US20140314698 ALDEHYDE DEHYDROGENASE INHIBITORS AS NOVEL DEPIGMENTING AGENTS  
The present invention provides methods and compositions for reducing pigmentation.
US20140313510 MULTIPLEX FLUORESCENT PARTICLE DETECTION USING SPATIALLY DISTRIBUTED EXCITATION  
A chip-scale optical approach to performing multi-target detection is based on molecular biosensing using fiber-optic based fluorescence or light scattering detection in liquid-core waveguides....
US20140313507 OPTOFLUIDIC DEVICES AND METHODS FOR SENSING SINGLE PARTICLES  
This disclosure provides systems, methods, and apparatus related to optofluidic devices. In one aspect, an optofluidic device includes a substrate, a first nanostructure, a second nanostructure,...
US20140313310 METHODS FOR OPTICAL AMPLIFIED IMAGING USING A TWO-DIMENSIONAL SPECTRAL BRUSH  
An apparatus and method for ultrafast real-time optical imaging that can be used for imaging dynamic events such as microfluidics or laser surgery is provided. The apparatus and methods encode...
US20140312421 Vapor-Trapping Growth of Single-Crystalline Graphene Flowers  
A method for growing a graphene layer on a metal foil includes placing a vessel into a chemical vapor deposition chamber, the vessel having a metal foil positioned therein. The method includes...
US20140311481 Novel compositions and methods useful for ionic liquid treatment of biomass  
The present invention provides for novel compositions and methods for recycling or recovering ionic liquid used in IL pretreated cellulose and/or lignocellulosic biomass (LBM).
US20140311347 POLANILINE BASED MEMBRANES FOR SEPARATION OF CARBON DIOXIDE AND METHANE  
Various embodiments demonstrate that an in-situ polymerization enables deposition of a homogeneous polyaniline layer with a controlled thickness on top of a porous polypropylene support....
8868867 Method for reducing latency of accessing data stored in a file system on a computer storage device by caching file system permission information in the computer storage device  
Systems and methods of storage device access are provided, where the operating system copies permission and mapping information to the storage array and/or to the application program's memory. The...
8868169 Method and system for detection of biological rhythm disorders  
System, assembly and method are provided to facilitate reconstruction of cardiac information representing a complex rhythm disorder associated with a patient's heart to indicate a source of the...
8867831 Image enhancement using modulation strength map and modulation kernel  
An image enhancement system may generate a net signed fractional modulation value at each location in an image using a modulation strength map (MSM) in combination with a modulation kernel F(θ). ...
8867510 Methods and apparatus to utilize network coding in a wireless network  
Methods and apparatus to utilize network coding in a wireless network are disclosed. A disclosed example method includes receiving a first packet flow at a first node from a second node that is...
8866149 Method for the reuse of gallium nitride epitaxial substrates  
A method for the reuse of gallium nitride (GaN) epitaxial substrates uses band-gap-selective photoelectrochemical (PEC) etching to remove one or more epitaxial layers from bulk or free-standing GaN...
8866126 Anisotropic strain control in semipolar nitride quantum wells by partially or fully relaxed aluminum indium gallium nitride layers with misfit dislocations  
An epitaxial structure for a III-Nitride based optical device, comprising an active layer with anisotropic strain on an underlying layer, where a lattice constant and strain in the underlying layer...
8866063 Lens-free wide-field super-resolution imaging device  
A system for imaging objects within a sample includes an image sensor and a sample holder configured to hold the sample, the sample holder disposed adjacent to the image sensor. The system further...
8865914 Fluorescent probes for detection of copper  
The invention provides fluorescent sensors for the selective detection of a metal such as copper. The sensors may be considered to be derivatives of cyanine, fluorescein, rhodamine, rhodol, Tokyo...
8865873 Internalizing human monoclonal antibodies targeting prostate cancer cells in situ  
This invention provides a method that allows selection of antibodies against cells (e.g., tumor cells) in situ using laser capture microdissection. By restricting antibody selection to binders of...
8865719 Substituted heterocycles and their use as allosteric modulators of nicotinic and GABAA receptors  
The present invention is related to heterocycles represented by a compound of Formula I that are novel allosteric modulators of α7 nAChRs and/or GABAA receptors. The invention also discloses the ...
8865708 Methods and compositions for inhibition of the transitional endoplasmic reticulum ATPase  
Compounds of Formulas I-XLIII are identified as direct inhibitors of p97 ATPase or of the degradation of a p97-dependent ubiquitin-proteasome system (UPS) substrate. Methods and compositions are...
8865646 Dietary compositions and methods for protection against chemotherapy, radiotherapy, oxidative stress, and aging  
The present invention relates to dietary compositions comprising reduced level of methionine, tryptophan, all amino acids, or protein, dietary compositions comprising glycerol as a substitute for...
8865469 Methods of transforming a Listeria  
Site-specific Listeria integration vectors and methods for their use are provided. The subject vectors include a bacteriophage integrase gene and a bacteriophage attachment site, where in many...
8863773 Fluid metering device using free-moving piston  
A fluid metering device may meter the flow of fluid. The device may have a main chamber and a piston configured and oriented to reciprocate within the main chamber. The piston may be configured and...
US20140310837 Engineering Single-Gene-Controlled Staygreen Potential Into Plants  
The enzymes of the ACC synthase family are used in producing ethylene. Nucleotide and polypeptide sequences of ACC synthases are provided along with knockout plant cells having inhibition in...
US20140310495 COLLECTIVE MEMORY TRANSFER DEVICES AND METHODS FOR MULTIPLE-CORE PROCESSORS  
This disclosure provides systems, methods, and apparatus for collective memory transfers. A control unit may be configured to coordinate a transfer of data between a memory and processor cores. For...
US20140310467 MULTIPLE-CORE COMPUTER PROCESSOR FOR REVERSE TIME MIGRATION  
A multi-core computer processor including a plurality of processor cores interconnected in a Network-on-Chip (NoC) architecture, a plurality of caches, each of the plurality of caches being...
US20140309974 OPTIMIZATION OF INPUT PARAMETERS OF A COMPLEX SYSTEM BASED ON MULTIPLE CRITERIA  
A method of combinatorial optimization includes: (1) defining an objective function to optimize a combination of N input parameters of a complex system, wherein the objective function includes a...
US20140309579 BALLOON CATHETER METHOD FOR REDUCING RESTENOSIS VIA IRREVERSIBLE ELECTROPORATION  
Restenosis or neointimal formation may occur following angioplasty or other trauma to an artery such as by-pass surgery. This presents a major clinical problem which narrows the artery. The...