Patents and Patent Applications from University of California System


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9719999 Highly sensitive system and method for analysis of troponin  
The invention provides methods, compositions, kits, and systems for the sensitive detection of cardiac troponin. Such methods, compositions, kits, and systems are useful in diagnosis, prognosis,...
9719991 Devices for detecting a particle in a sample and methods for use thereof  
Devices for detecting a particle in a fluid sample are provided. The device includes a segmented microfluidic conduit configured to carry a flow of a fluid sample, where the conduit includes one...
9719930 Device and methods of detection of airborne agents  
Provided are methods, devices and systems that utilize free-surface fluidics and SERS for analyte detection with high sensitivity and specificity. The molecules can be airborne agents, including...
9719127 Dual inducible vectors and cell lines  
The invention pertains to a novel cell line, an HIV tat-rev dependent GFP-Gaussia luciferase Reporter cell line, known henceforth as the GGR cell line, that detects pseudotype and replication...
9719084 Co-transcriptional assembly of modified RNA nanoparticles  
A method is provided for generating RNA nanoparticles having modified nucleotides and/or having increased nuclease resistance where the RNA nanoparticles are formed cotranscriptionally by T7 RNA...
9719028 Method for predicting adsorbent performance  
A method for predicting selective performance of an adsorbent is disclosed. The adsorbent is selected from a list of metals and/or metal cations for use in removing contaminants as thiophene...
9718922 Polymerization enhanced by nanostructures under X-ray irradiation  
The methods disclosed herein are directed to methods of enhancing formation of a polymer from a monomer on a metal-based nanoparticle under X-ray irradiation and compositions produced by such...
9718921 Amphiphilic derivatives of thioether containing block copolypeptides  
Methods for preparation of novel amphiphilic derivatives of thioether containing block copolypeptides with narrow chain length distributions are described. These block copolymers can be chemically...
9718094 Method of forming oriented block copolymer line patterns, block copolymer line patterns formed thereby, and their use to form patterned articles  
A block copolymer film having a line pattern with a high degree of long-range order is formed by a method that includes forming a block copolymer film on a substrate surface with parallel facets,...
9718049 Oxide materials and synthesis by fluoride/chloride anion promoted exfoliation  
The present invention is directed to the synthesis of novel delaminated layered zeolite precursor materials prepared by fluoride/chloride anion-promoted exfoliation. The method comprises, for...
9718048 Oxide materials and synthesis by fluoride/chloride anion promoted exfoliation  
The present invention is directed to the synthesis of novel delaminated layered zeolite precursor materials prepared by fluoride/chloride anion-promoted exfoliation. The method comprises, for...
9717827 Immunomodulatory materials for implantable medical devices  
The present invention relates to biomaterials that interact with and regulate immune functions, as well as implantable materials and devices. In one embodiment, the present invention provides an...
9717742 Oxysterol analogue OXY133 induces osteogenesis and hedgehog signaling and inhibits adipogenesis  
This invention relates, e.g., to a synthetic compound, Oxy133, having the structure [Formula I] or a bioactive or pharmaceutical composition comprising Oxy133 and a pharmaceutically acceptable...
9717436 Method and system for detection of biological rhythm disorders  
System, assembly and method are provided to facilitate reconstruction of cardiac information representing a complex rhythm disorder associated with a patient's heart to indicate a source of the...
US20170215313 Walnut variety named 'DURHAM'  
A new walnut variety (Juglans regia) designated as ‘Durham’ is provided. This variety has a harvest date 10 days earlier than walnut variety ‘Chandler’, and produces a walnut that is jumbo in size...
US20170214502 APPARATUS AND METHOD FOR TRANSMITTING AND RECEIVING SIGNAL IN WIRELESS COMMUNICATION SYSTEM  
The present disclosure relates to a pre-5th-generation (5G) or 5G communication system to be provided for supporting higher data rates beyond 4th-generation (4G) communication system such as a...
US20170213657 HIGH-VOLTAGE DEVICES  
The present disclosure provides supercapacitors that may avoid the shortcomings of current energy storage technology. Provided herein are supercapacitor devices, and methods of fabrication thereof...
US20170213656 GRAPHENE FRAMEWORKS FOR SUPERCAPACITORS  
The present disclosure provides supercapacitors that may avoid shortcomings of current energy storage technology. Provided herein are materials and fabrication processes of such supercapacitors....
US20170213134 SPARSE AND EFFICIENT NEUROMORPHIC POPULATION CODING  
Example embodiments for efficient neuromorphic population coding are described. In one case, individual instances of input stimuli are evaluated using a set of feature encoding units to generate a...
US20170212251 MULTIPLE SPATIAL RESOLUTION SCINTILLATION DETECTORS  
High sensitivity and high spatial resolution detection modules are provided that that can be built into an array or incorporated into PET or other types of gamma ray detectors and imagers. Each...
US20170211515 Recirculating Noble Gas Internal Combustion Power Cycle  
The present technology provides embodiments of recirculating noble gas combustion power cycles and systems including engines utilizing these power cycles. Embodiments of the cycles may include a...
US20170211044 REVERSIBLE STENCILS FOR FABRICATING MICRO-TISSUES  
The invention relates to devices, methods, kits, and compositions for in vitro generation of three-dimensional micro-tissues that are accurate models of heart, skeletal muscle, neuronal, and other...
US20170210834 CO-SUPPORTED CATALYSTS FOR THE TANDEM TRIMERIZATION AND POLYMERIZATION OF ETHYLENE TO PRODUCE LINEAR LOW DENSITY POLYETHYLENE  
Linear low density polyethylene (LLDPE) is produced from an ethylene-only feed over a tandem catalyst system consisting of a phenoxy-imine titanium trimerization catalyst and a silylene-linked...
US20170210793 Novel Treatment for Polycystic Kidney Disease  
The invention comprises the administration of dimeric IgA or pentameric IgM antibodies to animals, including human patients, suffering from a disease state wherein the polymeric immunoglobulin...
US20170210780 Peptide Fragments of Netrin-1 and Compositions and Methods Thereof  
Disclosed herein are peptide fragments derived from netrin-1 and compositions thereof and methods of using thereof. In some embodiments, the present invention provides a peptide that is 8-65 amino...
US20170209983 BINDER COMPOSITIONS OF TUNGSTEN TETRABORIDE AND ABRASIVE METHODS THEREOF  
Disclosed herein, in certain embodiments, are composite materials, methods, tools and abrasive materials comprising a tungsten-based metal composition and an alloy. In some cases, the composite...
US20170209834 SELF-ADAPTIVE CONTROL AND OPTIMIZATION OF MEMBRANE FILTRATION  
An apparatus includes 1) a filtration device including a filtration module to generate a filtrate from an input stream; 2) a desalination device fluidly connected to the filtration device; and 3)...
US20170209698 PATIENT-SPECIFIC MODELING OF VENTRICULAR ACTIVATION PATTERN USING SURFACE ECG-DERIVED VECTORCARDIOGRAM IN BUNDLE BRANCH BLOCK  
In some example embodiments, there may be provided a method. The method may include receiving three-dimensional image data representative of a heart; receiving electrical data representative of an...
US20170209576 DELIVERY COMPOSITIONS AND METHODS  
This disclosure describes composition and methods for delivering a substance to a subject. Generally, the compositions include a liposome that includes a lysolipid and a cargo composition at least...
US20170209544 A PEPTIDE THERAPY TO COUNTERACT INSULIN RESISTANCE AND TYPE 2 DIABETES  
Compositions comprising an antagonist of pancreastatin are provided. The beneficial use of the compositions for treating insulin resistance, diabetes, especially type II diabetes, inflammation,...
US20170209460 COMPOSITIONS AND METHODS FOR TREATING DENGUE VIRUS INFECTION  
The present disclosure provides methods of treating a flavivirus infection, and compositions for use in the methods.
US20170209104 SYSTEM AND METHODS FOR GENERATING PREDICTIVE COMBINATIONS OF HOSPITAL MONITOR ALARMS  
Systems and methods are disclosed for monitoring data associated with a plurality of physiological characteristics of a patient, comprising: the methods include generating a set of super-alarm...
US20170209089 Predicting Weight Loss and Fat Metabolism Using Optical Signal Changes in Fat  
A quantitative, non-invasive optical spectroscopy technique for measuring dynamic changes in adipose tissue structure and metabolism in vivo. The technique requires multiple wavelengths of light...
US20170209083 HAND-HELD OPTICAL SCANNER FOR REAL-TIME IMAGING OF BODY COMPOSITION AND METABOLISM  
A low cost portable high speed quantitative system for diffuse optical spectroscopic imaging of human tissue. The hybrid system (CWFD) can measure absolute optical properties from 660 nm to 980 nm...
US20170209045 SYSTEM AND METHOD FOR INTRAOCULAR PRESSURE SENSING  
IOP sensor and system for measuring intraocular pressure are disclosed herein. Examples embodiments of the IOP sensor can include: a chamber having a first wall and a second wall opposing the...
US20170208793 BIODEGRADABLE BAIT STATION FOR LIQUID ANT BAIT  
A biodegradable bait station is disclosed that can be used with liquid baits targeting pest ants in urban, agricultural, and natural setting, which can overcome several limitations that most of...
9717145 Through silicon vias and thermocompression bonding using inkjet-printed nanoparticles  
Apparatus and method for filling and optionally bumping through-silicon vias (TSVs) in device circuits utilizing inkjet printheads for ejecting sufficiently small droplets of conductive...
9716485 Frequency divider apparatus  
A frequency divider apparatus includes a micro-electro-mechanical system (“MEMS”) divider that is configured to be driven by an input signal. The MEMS divider includes a passive mechanical device...
9716299 Graphene based thermal interface materials and methods of manufacturing the same  
Thermal interface materials and methods of manufacturing the same are disclosed. The thermal interface material can include a matrix and a filler. The filler can include graphene and multilayer...
9715099 Maskless imaging of dense samples using multi-height lensfree microscope  
A method of imaging includes illuminating a sample spaced apart from an image sensor at a multiple distances. Image frames of the sample obtained at each distance are registered to one another and...
9714874 Determining sensible heat flux without calibration  
By correcting temperature measurements above a surface (such as the ground) for the first-order filtering associated with the thermal inertia of a temperature sensor (such as a thermocouple) that...
9714288 Antisense compounds and uses thereof  
The present disclosure provides compounds comprising modified oligonucleotides and anti-CD22 antibodies. Certain such modified oligonucleotides conjugated to anti-CD22 antibodies are useful for...
9713628 Transplantation of neural cells  
Restoration or increase of inhibitory interneuron function in vivo is achieved by transplantation of MGE cells into the brain. Compositions containing MGE cells are provided as are uses to treat...
9713607 Salinosporamides and methods of use thereof  
The present invention is based on the discovery that certain fermentation products of the marine actinomycete strains CNB392 and CNB476 are effective inhibitors of hyperproliferative mammalian...
9713459 Method and system for in vivo hydrogen peroxide detection with ultrasound  
A method and system are provided for detection of localized hydrogen peroxide within tissue by introducing a catalase-containing material into at location of interest, positioning an ultrasound...
9713339 Method for debittering olives  
A method for debittering olives is described. The method includes contacting olive flesh with a granular polymeric resin under conditions sufficient to remove one or more bittering compounds from...
US20170207532 INDENTED ANTENNA ARRAY FOR TRANSMITTER TO RECEIVER ISOLATION  
An apparatus and method for enhancing full-duplex radio communications using an indented transmitter and receiver antenna. A multi-element antenna array is configured with each antenna coupled to...
US20170206316 BAMBAM: PARALLEL COMPARATIVE ANALYSIS OF HIGH-THROUGHPUT SEQUENCING DATA  
A differential sequence object is constructed on the basis of alignment of sub-strings via incremental synchronization of sequence strings using known positions of the sub-strings relative to a...
US20170205402 IN PLANTA LEAF BIOENSOR  
A method for detecting an analyte in a plant is provided. The method includes injecting an analyte-capture agent into a leaf of a plant, and in the leaf, optically detecting complexes formed by...
US20170204500 EVAPORATION-BASED METHOD FOR MANUFACTURING AND RECYCLING OF METAL MATRIX NANOCOMPOSITES  
A manufacturing method includes: 1) forming a melt including one or more metals; 2) introducing nanostructures into the melt at an initial volume fraction of the nanostructures; and 3) at least...