Patents and Patent Applications from University of Arkansas


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7632929 Methamphetamine-like hapten compounds, linkers, carriers and compositions and uses thereof  
The invention generally relates to hapten compounds comprising either (+) methamphetamine or (+) amphetamine conjugated to a linker. Generally speaking, hapten compounds of the invention may be...
7632428 Doped semiconductor nanocrystals and methods of making same  
A method of synthesizing doped semiconductor nanocrystals. In one embodiment, the method includes the steps of combining a metal oxide or metal salt precursor, a ligand, and a solvent to form a...
7608240 Nanotubes for cancer therapy and diagnostics  
The present invention provides a novel approach to cancer therapy and diagnostics that utilizes nanotubes and other similar nanostructures as both an indirect source of radiation therapy (BNCT),...
US20090263839 ACETAMINOPHEN-PROTEIN ADDUCT ASSAY DEVICE AND METHOD  
The present invention describes devices and methods for detecting and measuring the amount of acetaminophen-protein adducts in a sample.
US20090257954 Development of a simple animal model for infection by viruses and other obligate intracellular parasites  
The present invention provides methods for studying pathogenesis of mammalian viruses. In particular, the present invention provides a nonhuman animal model system for studying disease mechanisms...
US20090257945 METHODS OF MAKING HORIZONTALLY ORIENTED LONG CARBON NANOTUBES AND APPLICATIONS OF SAME  
An apparatus and method for synthesizing nanostructures in a reactor having a reaction zone and a conductive susceptor positioned in the reaction zone. In one embodiment, the method has the steps...
7601800 Compositions and methods for monitoring breast cancer treatment  
The present invention provides compositions and processes for preparing the same wherein the compositions are useful for monitoring breast cancer treatment.
US20090239912 CONCENTRATED, NON-FOAMING SOLUTION OF QUATERNARY AMMONIUM COMPOUNDS AND METHODS OF USE  
A concentrated quaternary ammonium compound (QAC) solution comprising a QAC with a concentration from greater than about 10% by weight and at least one solubility enhancing agent, such as an...
7593250 Ferroelectric nanostructure having switchable multi-stable vortex states  
A ferroelectric nanostructure formed as a low dimensional nano-scale ferroelectric material having at least one vortex ring of polarization generating an ordered toroid moment switchable between...
7572355 Electrochemistry using permanent magnets with electrodes embedded therein  
Devices and methods of enhancing mass transport proximate a surface of an electrode immersed in a liquid are disclosed. One aspect of the device comprises an electrode embedded in a sintered or...
US20090180119 MULTI-COLOR CAVITY RINGDOWN BASED DETECTION METHOD AND APPARATUS  
A multi-color cavity ringdown based spectrometer is housed in a light tight enclosure to detect the presence of trace quantities of gas phase molecules emanating from explosives, drugs, or...
7553654 Non-toxic endophytes, plants injected therewith and methods for injecting plants  
Isolated endophytes selected from the group consisting of ATCC Deposit No. PTA-6499, PTA-8827, PTA-8828, and PTA-8829 are disclosed. Seeds of plants stably infected with these endophytes are also...
US20090156932 DEVICE AND METHOD FOR IN VIVO FLOW CYTOMETRY USING THE DETECTION OF PHOTOACOUSTIC WAVES  
A photoacoustic flow cytometry (PAFC) device for the in vivo detection of cells circulating in blood or lymphatic vessels is described. Ultrasound transducers attached to the skin of an organism...
7541045 Concentrated, non-foaming solution of quaternary ammonium compounds and methods of use  
A concentrated quaternary ammonium compound (QAC) solution comprising a QAC with a concentration from greater than about 10% by weight and at least one solubility enhancing agent, such as an...
7537901 Extracellular serine protease  
The present invention provides a DNA encoding a TADG-14 protein selected from the group consisting of: (a) isolated DNA which encodes a TADG-14 protein; (b) isolated DNA which hybridizes to...
US20090124608 CB2 Receptor Modulators In Neurodegenerative Diseases And Applications Of The Same  
Compositions for the treatment of neurodegenerative diseases are disclosed. Methods of treating and monitoring progression of a neurodegenerative disease are disclosed. According to the present...
7531149 Synthetic control of metal oxide nanocrystal sizes and shapes  
A general, reproducible, and simple synthetic method that employs readily available chemicals permits control of the size, shape, and size distribution of metal oxide nanocrystals. The synthesis...
7510760 Nanoparticle compositions, coatings and articles made therefrom, methods of making and using said compositions, coatings and articles  
Compositions comprising nanoparticles, microparticles, and combinations thereof, the particles may be overcoated particles. Composite coatings and coated articles made therefrom, the coatings...
US20090060903 Pharmaceutical Compositions Comprising an Anti-Teratogenic Compound and Applications of the Same  
Pharmaceutical compositions comprising anti-teratogenic agents are disclosed. Additionally, pharmaceutical compositions comprising anti-neoplastic agents and anti-teratogenic agents are disclosed....
7498411 P49/STRAP is a novel protein involved in gene regulation and cell proliferation  
The invention provides isolated p49/STRAP protein, and isolated nucleic acids encoding a p49/STRAP protein. The inventors have discovered a new protein, named p49/STRAP that is expressed in cardiac...
US20090042850 COMPOSITIONS AND METHODS FOR CYTOPROTECTION  
The present invention provides compositions and methods for cytoprotection. In particular, it provides zinc chelate compositions comprising at least one zinc ion and at least one aminothiol ligand.
US20090035819 CA125 gene and its use for diagnostic and therapeutic interventions  
The CA125 gene has been cloned and multiple repeat sequences as well as the carboxy terminus have been identified. The CA125 molecule comprises three major domains: an extracellular amino terminal...
7485708 Nucleic acids encoding ara h 3 polypeptides  
It has been determined that allergens, which are characterized by both humoral (IgE) and cellular (T cell) binding sites, can be modified to be less allergenic by modifying the IgE binding sites....
7479499 Methods of using thalidomide in combination with irinotecan  
This invention relates to compositions comprising thalidomide and irinotecan, which can be used in the treatment or prevention of colorectal cancer. The invention also relates to methods of...
7476551 Diagnosing atherosclerosis risk by measuring carbamylated low density lipoprotein levels  
The present invention provides a method of determining whether an individual is at risk for atherosclerosis, comprising the step of: measuring the level of carbamylated LDL in a sample obtained...
7473873 Apparatus and methods for synthesis of large size batches of carbon nanostructures  
An apparatus and method for synthesizing nanostructures. In one embodiment, the apparatus includes a reactor having a reaction zone and a conductive susceptor positioned in the reaction zone. The...
US20080318044 TITANATE NANOWIRE, TITANATE NANOWIRE SCAFFOLD, AND PROCESSES OF MAKING SAME  
In one aspect, the present invention relates to a synthetic nanostructure. In one embodiment, the synthetic nanostructure has a top region substantially comprising titanate nanowires, a middle...
7467928 Microfluidic device utilizing magnetohydrodynamics and method for fabrication thereof  
Microfluidic channels utilizing magnetohydrodynamics are used to pump very small volumes of solution. The channels have electrodes along the walls and a current carrying species within a solution...
7465855 Non-toxic endophytes, plants injected therewith and methods for injecting plants  
A grass with improved environmental stress tolerance and low animal toxicity is disclosed where the grass is infected with an isolated endophyte selected from the groups consisting of USDA-PI no....
7465537 Compounds and methods for inhibiting hepatitis C virus replication  
The inventors have discovered that an ATPase-deficient dominant-negative mutant NS3 protein of hepatitis C virus inhibits activity of the wild-type NS3 protein and inhibits replication of hepatitis...
US20080296491 METHOD AND APPARATUS TO DETECT CHEMICAL VAPORS  
Means and method of rapid detection of a compound of interest from an air sample is shown. An air sample is collected, and concentration of the compound of interest can be increased. A portable...
7459437 Molecular determinants of myeloma bone disease and uses thereof  
To identify molecular determinants of lytic bone disease in multiple myeloma, the expression profiles of ˜12,000 genes in CD138-enriched plasma cells from newly diagnosed multiple myeloma patients...
7456551 Packaging and integration system for micro sensors in the marine environment  
The integrated unmanned, affordable, microsystem in accordance with the present invention is used to deploy physical or chemical sensors for continuous monitoring of sea space over large time...
7456028 Electrochemical method for detecting water born pathogens  
A novel, surface immobilization electrochemical assay allows for rapid, accurate and highly sensitive detection of microorganisms and biological molecules. Known surface immobilization methods are...
US20080274280 Apparatus and methods for synthesis of large size batches of carbon nanostructures  
An apparatus and method for synthesizing nanostructures. In one embodiment, the apparatus includes a reactor having a reaction zone and a conductive susceptor positioned in the reaction zone. The...
US20080269159 COMPOSITIONS AND METHODS FOR REGULATION OF SMOOTH MUSCLE CELLS AND BLOOD PRESSURE  
The invention encompasses a composition for regulating smooth muscle cells. In particular, the invention encompasses a vector comprising a smooth muscle promoter operably-linked to a nucleic acid...
US20080264330 Production of nanostructure by curie point induction heating  
An apparatus for synthesizing nanostructures. In one embodiment, the apparatus includes a heating device that defines a reaction zone therein and a susceptor made of a ferromagnetic material with a...
7438933 Maternal multi-nutrient against diabetes-related birth defects  
The present invention provides uses of multi-nutrient supplements to rescue aberrant biochemical pathways and reduce birth defect caused by maternal diabetes. Choice of supplements is based on the...
7429697 Rice cultivar ‘Spring’  
A rice cultivar designated ‘Spring’ is disclosed. The invention relates to the seeds of rice cultivar ‘Spring’, to the plants of rice ‘Spring’ and to methods for producing a rice plant...
US20080229436 METHODS FOR IDENTIFYING MODULATORS OF LIFESPAN AND RESISTANCE TO OXIDATIVE STRESS  
The present invention provides methods for identifying agents that increase lifespan and increase resistance to oxidative and/or electrophilic stress. Also provided are methods for identifying...
US20080223851 APPARATUS AND METHODS FOR SYNTHESIS OF LARGE SIZE BATCHES OF CARBON NANOSTRUCTURES  
An apparatus and method for synthesizing nanostructures. In one embodiment, the apparatus includes a reactor having a reaction zone and a conductive susceptor positioned in the reaction zone. The...
US20080221216 Use of modafinil to treat spasticity  
The invention provides a method of reducing spasticity in a mammal involving administering modafinil or related compounds. The spasticity can be secondary to multiple sclerosis, spinal cord injury,...
RE40487 Method for forming a breast prothesis  
A method for forming the outer surface of a breast prosthesis is disclosed. A digital, three-dimensional image is formed of a patient's breast using a computerized scanner. A computer-controlled...
US20080206791 METHOD FOR DETECTING AN UNKNOWN CONTAMINANT CONCENTRATION IN A SUBSTANCE  
A method for determining a concentration of a contaminant in a first sample, the method including producing the first sample, including adding a plurality of immuno-beads to a test substance;...
US20080199885 Overexpression of mammaglobin B in ovarian and endometrial tumors - a new diagnostic and therapeutic marker  
The invention involves the discovery that the mammaglobin B gene is the single most overexpressed gene in primary ovarian serous papillary cancer over normal ovarian epithelium among over 14,000...
US20080199434 COMPOSITIONS AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR CONDITIONS  
The present invention provides methods and compositions for treating a cardiovascular condition. In particular, provided is a method comprising administering to a subject an agent that increases...
US20080193410 Immunotherapy of epithelial tumors using intralesional injection of antigens that induce a delayed type hypersensitivity reaction  
The pharmaceutical composition is useful for treating epithelial tumors in a subject and contains at least two antigens and a pharmaceutically acceptable carrier, where each of the antigens induces...
US20080175816 Maintenance and Propagation of Mesenchymal Stem Cells  
Various embodiments of the present invention include compositions, materials and methods for maintaining and propagating mammalian mesenchymal stem cells in an undifferentiated state in the absence...
US20080171392 IN SITU TEST FOR DETERMINING DRUG HISTORY  
The present invention relates generally to kits, compositions and methods useful in the qualitative analysis of the presence of chemicals used and produced in the manufacture of illegal drugs. The...
US20080160024 INHIBITION OF CANCER METASTASIS  
The present invention provides a method for inhibiting tumor cell metastasis in a subject. In particular, the method comprises administering a glycoprotein lbα inhibitor to the subject. The method...
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